P02817
type: UnificationXref
id: P02817
db: PANTHER Pathway Component

P02818
type: UnificationXref
id: P02818
db: PANTHER Pathway Component

Ureidoglycolate dehydrogenase (NAD(+))
type: ProteinReference
xref: uniprot P77555 18
organism: Escherichia coli

ncbitaxon 3702 44
type: UnificationXref
id: 3702
db: ncbitaxon

P02819
type: UnificationXref
id: P02819
db: PANTHER Pathway Component

Putative glycerate kinase
type: ProteinReference
xref: uniprot Q9X804 7
organism: Streptomyces coelicolor

uniprot P18407 23
type: UnificationXref
id: P18407
db: uniprot

uniprot Q9Z5A1 17
type: UnificationXref
id: Q9Z5A1
db: uniprot

Tartronate semi-aldehyde dehydrogenase
type: ProteinReference
xref: P02823
standard name: Tartronate semialdehyde dehydrogenase
comment: ENTITY_REFERENCE_ID_DESC=Allantoin degradation.PROTEIN.GENERIC.Tartronate semi-_br_aldehyde dehydrogenase
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Tartronate semialdehyde dehydrogenase Synonym: Synonym not specified Accession: P02823
member entity reference: 2-hydroxy-3-oxopropionate reductase

uniprot Q94AP0 43
type: UnificationXref
id: Q94AP0
db: uniprot

PARTICIPANT STOICHIOMETRY r7 64
type: Stoichiometry
physical entity: glycerate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r7 63
type: Stoichiometry
physical entity: ATP
stoichiometric coefficient: 1.0

ncbitaxon 208964 16
type: UnificationXref
id: 208964
db: ncbitaxon

Allantoicase
type: ProteinReference
xref: uniprot P18407 23
organism: Neurospora crassa

Anopheles gambiae
type: BioSource
xref: ncbitaxon 7165 42

Allantoinase
type: Protein
entity reference: Allantoinase
comment: SPECIES_TYPE=PROTEIN

uniprot Q9JHX6 35
type: UnificationXref
id: Q9JHX6
db: uniprot

uniprot O13843 9
type: UnificationXref
id: O13843
db: uniprot

PARTICIPANT STOICHIOMETRY r6 70
type: Stoichiometry
physical entity: glycerate
stoichiometric coefficient: 1.0

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__H2O-_Ureidoglycolate-RIGHT__glyoxylate-_NH3-_CO2-_r4
controller: Ureidoglycolate hydrolase

Bacillus subtilis
type: BioSource
xref: ncbitaxon 224308 5

ncbitaxon 83333 3
type: UnificationXref
id: 83333
db: ncbitaxon

Probable allantoicase
type: ProteinReference
xref: uniprot Q09913 26
organism: Schizosaccharomyces pombe

Glyoxylate carboligase
type: ProteinReference
xref: uniprot Q9I3L0 15
organism: Pseudomonas aeruginosa

Ureidoglycolate hydrolase
type: Protein
entity reference: Ureidoglycolate hydrolase
comment: SPECIES_TYPE=PROTEIN

Macaca mulatta
type: BioSource
xref: ncbitaxon 9544 20

PARTICIPANT STOICHIOMETRY r7 65
type: Stoichiometry
physical entity: ADP
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r7 66
type: Stoichiometry
physical entity: 3-phosphoglycerate
stoichiometric coefficient: 1.0

Ureidoglycolate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Mus musculus
type: BioSource
xref: ncbitaxon 10090 36

PARTICIPANT STOICHIOMETRY r6 67
type: Stoichiometry
physical entity: tartronate semialdehyde
stoichiometric coefficient: 1.0

ncbitaxon 9598 22
type: UnificationXref
id: 9598
db: ncbitaxon

Ureidoglycolate lyase
type: ProteinReference
xref: uniprot P32459 11
organism: Saccharomyces cerevisiae

PARTICIPANT STOICHIOMETRY r6 68
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r6 69
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r5 71
type: Stoichiometry
physical entity: glyoxylate
stoichiometric coefficient: 1.0

Saccharomyces cerevisiae
type: BioSource
xref: ncbitaxon 559292 12

Allantoin degradation
type: Pathway
pathway component: STATE_TRANSITION_LEFT__H2O-_Ureidoglycolate-RIGHT__glyoxylate-_NH3-_CO2-_r4
pathway component: STATE_TRANSITION_LEFT__H2O-_allantoate-RIGHT__urea-_Ureidoglycolate-_r2
pathway component: STATE_TRANSITION_LEFT__NADP-_Ureidoglycolate-RIGHT__NADPH-_oxalureate-_r3
pathway component: STATE_TRANSITION_LEFT__glyoxylate-RIGHT__tartronate_semialdehyde-_CO2-_r5
pathway component: STATE_TRANSITION_LEFT__ATP-_glycerate-RIGHT__ADP-_3_phosphoglycerate-_r7
pathway component: STATE_TRANSITION_LEFT__tartronate_semialdehyde-_NADPH-RIGHT__NADP-_glycerate-_r6
pathway component: STATE_TRANSITION_LEFT__allantoin-_H2O-RIGHT__allantoate-_r1
xref: PANTHER Pathway P02725 1
comment: MODEL_NOTES=The degradation of allantoin, a polyamine that can be broken down and utilized as a nitrogen source under anaeorbic conditions. Website=www.biocyc.org/Ecoli/Pathways/ free text=Voet and Voet (textbook) Biochemistry

allantoate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r5 73
type: Stoichiometry
physical entity: CO2
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r5 72
type: Stoichiometry
physical entity: tartronate semialdehyde
stoichiometric coefficient: 1.0

ncbitaxon 7165 42
type: UnificationXref
id: 7165
db: ncbitaxon

STATE_TRANSITION_LEFT__glyoxylate-RIGHT__tartronate_semialdehyde-_CO2-_r5
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 71
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 73
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 72
left: glyoxylate
interaction type: STATE_TRANSITION
right: tartronate semialdehyde
right: CO2

Drosophila melanogaster
type: BioSource
xref: ncbitaxon 7227 49

PANTHER Pathway P02725 1
type: UnificationXref
id: P02725
db: PANTHER Pathway

uniprot Q9X804 7
type: UnificationXref
id: Q9X804
db: uniprot

uniprot P77731 13
type: UnificationXref
id: P77731
db: uniprot

Probable allantoicase
type: ProteinReference
xref: uniprot Q6AYP0 29
organism: Rattus norvegicus

uniprot Q9RKU4 37
type: UnificationXref
id: Q9RKU4
db: uniprot

STATE_TRANSITION_LEFT__tartronate_semialdehyde-_NADPH-RIGHT__NADP-_glycerate-_r6
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 68
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 69
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 70
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 67
left: tartronate semialdehyde
left: NADPH
interaction type: STATE_TRANSITION
right: NADP
right: glycerate

STATE_TRANSITION_LEFT__H2O-_Ureidoglycolate-RIGHT__glyoxylate-_NH3-_CO2-_r4
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 74
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 77
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 76
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 75
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 78
left: Ureidoglycolate
left: H2O
interaction type: STATE_TRANSITION
right: NH3
right: glyoxylate
right: CO2

Glycerate kinase II
type: ProteinReference
xref: P02817
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Glycerate kinase II Synonym: Synonym not specified Accession: P02817
comment: ENTITY_REFERENCE_ID_DESC=Allantoin degradation.PROTEIN.GENERIC.Glycerate kinase II
member entity reference: Glycerate 2-kinase
member entity reference: Putative glycerate kinase
member entity reference: Glycerate kinase
member entity reference: Glycerate 3-kinase

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__NADP-_Ureidoglycolate-RIGHT__NADPH-_oxalureate-_r3
controller: Ureidoglycolate dehydrogenase

ncbitaxon 9544 20
type: UnificationXref
id: 9544
db: ncbitaxon

uniprot Q6AYP0 29
type: UnificationXref
id: Q6AYP0
db: uniprot

uniprot Q9I3L0 15
type: UnificationXref
id: Q9I3L0
db: uniprot

Glyoxylate carboligase
type: ProteinReference
xref: P02819
comment: ENTITY_REFERENCE_ID_DESC=Allantoin degradation.PROTEIN.GENERIC.Glyoxylate carboligase
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Glyoxylate carboligase Synonym: Synonym not specified Accession: P02819
member entity reference: Putative glyoxylate carboligase
member entity reference: Glyoxylate carboligase

Allantoicase
type: ProteinReference
xref: uniprot P25335 25
organism: Saccharomyces cerevisiae

uniprot P42100 4
type: UnificationXref
id: P42100
db: uniprot

Rattus norvegicus
type: BioSource
xref: ncbitaxon 10116 30

tartronate semialdehyde
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r3 55
type: Stoichiometry
physical entity: oxalureate
stoichiometric coefficient: 1.0

uniprot Q7QF02 41
type: UnificationXref
id: Q7QF02
db: uniprot

PARTICIPANT STOICHIOMETRY r3 54
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

ncbitaxon 10116 30
type: UnificationXref
id: 10116
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r3 53
type: Stoichiometry
physical entity: Ureidoglycolate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r3 52
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

Neurospora crassa
type: BioSource
xref: ncbitaxon 367110 24

ncbitaxon 8364 28
type: UnificationXref
id: 8364
db: ncbitaxon

ncbitaxon 224308 5
type: UnificationXref
id: 224308
db: ncbitaxon

P02822
type: UnificationXref
id: P02822
db: PANTHER Pathway Component

P02823
type: UnificationXref
id: P02823
db: PANTHER Pathway Component

Glycerate kinase II
type: Protein
entity reference: Glycerate kinase II
comment: SPECIES_TYPE=PROTEIN

Probable allantoicase
type: ProteinReference
xref: uniprot Q8N6M5 33
organism: Homo sapiens

P02820
type: UnificationXref
id: P02820
db: PANTHER Pathway Component

P02821
type: UnificationXref
id: P02821
db: PANTHER Pathway Component

Allantoate amidohydrolase
type: ProteinReference
xref: P02821
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Allantoin degradation.PROTEIN.GENERIC.Allantoate_br_amidohydrolase
comment: ENTITY_REFERENCE_NOTES=Long Name: Allantoate amidohydrolase Synonym: Synonym not specified Accession: P02821
member entity reference: Probable allantoicase
member entity reference: Allantoicase
member entity reference: ALLC isoform 1
member entity reference: Uncharacterized protein

glycerate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ncbitaxon 367110 24
type: UnificationXref
id: 367110
db: ncbitaxon

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__allantoin-_H2O-RIGHT__allantoate-_r1
controller: Allantoinase

ncbitaxon 10090 36
type: UnificationXref
id: 10090
db: ncbitaxon

Allantoinase
type: ProteinReference
xref: uniprot Q9RV76 46
organism: Deinococcus radiodurans

Allantoinase
type: ProteinReference
xref: uniprot O32137 38
organism: Bacillus subtilis

uniprot P0ABQ2 50
type: UnificationXref
id: P0ABQ2
db: uniprot

uniprot P77555 18
type: UnificationXref
id: P77555
db: uniprot

Glyoxylate carboligase
type: ProteinReference
xref: uniprot P0AEP7 14
organism: Escherichia coli

ADP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__glyoxylate-RIGHT__tartronate_semialdehyde-_CO2-_r5
controller: Glyoxylate carboligase

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__tartronate_semialdehyde-_NADPH-RIGHT__NADP-_glycerate-_r6
controller: Tartronate semi-aldehyde dehydrogenase

Schizosaccharomyces pombe
type: BioSource
xref: ncbitaxon 284812 10

uniprot Q9VWW1 48
type: UnificationXref
id: Q9VWW1
db: uniprot

Streptomyces coelicolor
type: BioSource
xref: ncbitaxon 100226 8

STATE_TRANSITION_LEFT__H2O-_allantoate-RIGHT__urea-_Ureidoglycolate-_r2
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 56
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 59
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 58
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 57
left: allantoate
left: H2O
interaction type: STATE_TRANSITION
right: Ureidoglycolate
right: urea

uniprot P77161 51
type: UnificationXref
id: P77161
db: uniprot

Allantoinase
type: ProteinReference
xref: uniprot Q9RKU5 45
organism: Streptomyces coelicolor

Probable allantoicase
type: ProteinReference
xref: uniprot Q9RKU4 37
organism: Streptomyces coelicolor

AGAP000239-PA
type: ProteinReference
xref: uniprot Q7QF02 41
organism: Anopheles gambiae

Pan troglodytes
type: BioSource
xref: ncbitaxon 9598 22

NH3
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Xenopus tropicalis
type: BioSource
xref: ncbitaxon 8364 28

STATE_TRANSITION
type: RelationshipTypeVocabulary

STATE_TRANSITION
type: InteractionVocabulary

oxalureate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q9RV76 46
type: UnificationXref
id: Q9RV76
db: uniprot

Allantoinase
type: ProteinReference
xref: uniprot Q94AP0 43
organism: Arabidopsis thaliana

H2O
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ncbitaxon 7227 49
type: UnificationXref
id: 7227
db: ncbitaxon

glyoxylate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Glycerate 3-kinase
type: ProteinReference
xref: uniprot P77364 6
organism: Escherichia coli

uniprot Q6DGA6 31
type: UnificationXref
id: Q6DGA6
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F6TE28 19
organism: Macaca mulatta

Allantoate amidohydrolase
type: Protein
entity reference: Allantoate amidohydrolase
comment: SPECIES_TYPE=PROTEIN

uniprot P23524 2
type: UnificationXref
id: P23524
db: uniprot

NADPH
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ALLC isoform 1
type: ProteinReference
xref: uniprot H2QHD7 21
organism: Pan troglodytes

uniprot Q8N6M5 33
type: UnificationXref
id: Q8N6M5
db: uniprot

ncbitaxon 9606 34
type: UnificationXref
id: 9606
db: ncbitaxon

uniprot Q9RKU5 45
type: UnificationXref
id: Q9RKU5
db: uniprot

Deinococcus radiodurans
type: BioSource
xref: ncbitaxon 243230 47

PARTICIPANT STOICHIOMETRY r4 78
type: Stoichiometry
physical entity: CO2
stoichiometric coefficient: 1.0

Uncharacterized protein, isoform A
type: ProteinReference
xref: uniprot Q9VWW1 48
organism: Drosophila melanogaster

uniprot P0AEP7 14
type: UnificationXref
id: P0AEP7
db: uniprot

PARTICIPANT STOICHIOMETRY r4 77
type: Stoichiometry
physical entity: NH3
stoichiometric coefficient: 1.0

uniprot P32375 39
type: UnificationXref
id: P32375
db: uniprot

uniprot H2QHD7 21
type: UnificationXref
id: H2QHD7
db: uniprot

PARTICIPANT STOICHIOMETRY r4 76
type: Stoichiometry
physical entity: glyoxylate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r4 75
type: Stoichiometry
physical entity: Ureidoglycolate
stoichiometric coefficient: 1.0

2-hydroxy-3-oxopropionate reductase
type: ProteinReference
xref: uniprot P77161 51
organism: Escherichia coli

Putative glyoxylate carboligase
type: ProteinReference
xref: uniprot Q9Z5A1 17
organism: Streptomyces coelicolor

Homo sapiens
type: BioSource
xref: ncbitaxon 9606 34

PARTICIPANT STOICHIOMETRY r4 74
type: Stoichiometry
physical entity: H2O
stoichiometric coefficient: 1.0

uniprot P32459 11
type: UnificationXref
id: P32459
db: uniprot

STATE_TRANSITION_LEFT__ATP-_glycerate-RIGHT__ADP-_3_phosphoglycerate-_r7
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r7 66
participant stoichiometry: PARTICIPANT STOICHIOMETRY r7 65
participant stoichiometry: PARTICIPANT STOICHIOMETRY r7 63
participant stoichiometry: PARTICIPANT STOICHIOMETRY r7 64
left: ATP
left: glycerate
interaction type: STATE_TRANSITION
right: ADP
right: 3-phosphoglycerate

Allantoinase
type: ProteinReference
xref: uniprot P32375 39
organism: Saccharomyces cerevisiae

uniprot F6TE28 19
type: UnificationXref
id: F6TE28
db: uniprot

Ureidoglycolate lyase
type: ProteinReference
xref: uniprot P77731 13
organism: Escherichia coli

3-phosphoglycerate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Allantoicase
type: ProteinReference
xref: uniprot Q6DGA6 31
organism: Danio rerio

PARTICIPANT STOICHIOMETRY r1 62
type: Stoichiometry
physical entity: allantoate
stoichiometric coefficient: 1.0

Arabidopsis thaliana
type: BioSource
xref: ncbitaxon 3702 44

PARTICIPANT STOICHIOMETRY r1 61
type: Stoichiometry
physical entity: H2O
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r1 60
type: Stoichiometry
physical entity: allantoin
stoichiometric coefficient: 1.0

ncbitaxon 559292 12
type: UnificationXref
id: 559292
db: ncbitaxon

Ureidoglycolate lyase
type: ProteinReference
xref: uniprot O13843 9
organism: Schizosaccharomyces pombe

STATE_TRANSITION_LEFT__allantoin-_H2O-RIGHT__allantoate-_r1
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 61
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 60
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 62
left: allantoin
left: H2O
interaction type: STATE_TRANSITION
right: allantoate

uniprot P77671 40
type: UnificationXref
id: P77671
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__H2O-_allantoate-RIGHT__urea-_Ureidoglycolate-_r2
controller: Allantoate amidohydrolase

Allantoinase
type: ProteinReference
xref: P02822
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Allantoinase Synonym: Synonym not specified Accession: P02822
comment: ENTITY_REFERENCE_ID_DESC=Allantoin degradation.PROTEIN.GENERIC.Allantoinase
member entity reference: Allantoinase
member entity reference: AGAP000239-PA
member entity reference: Uncharacterized protein, isoform A

Ureidoglycolate dehydrogenase
type: Protein
entity reference: Ureidoglycolate dehydrogenase
comment: SPECIES_TYPE=PROTEIN

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__ATP-_glycerate-RIGHT__ADP-_3_phosphoglycerate-_r7
controller: Glycerate kinase II

Allantoinase
type: ProteinReference
xref: uniprot P77671 40
organism: Escherichia coli

PARTICIPANT STOICHIOMETRY r2 59
type: Stoichiometry
physical entity: Ureidoglycolate
stoichiometric coefficient: 1.0

allantoin
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r2 57
type: Stoichiometry
physical entity: allantoate
stoichiometric coefficient: 1.0

Glyoxylate carboligase
type: Protein
entity reference: Glyoxylate carboligase
comment: SPECIES_TYPE=PROTEIN

Ureidoglycolate hydrolase
type: ProteinReference
xref: P02818
comment: ENTITY_REFERENCE_ID_DESC=Allantoin degradation.PROTEIN.GENERIC.Ureidoglycolate_br_hydrolase
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Ureidoglycolate hydrolase Synonym: Synonym not specified Accession: P02818
member entity reference: Ureidoglycolate lyase

PARTICIPANT STOICHIOMETRY r2 58
type: Stoichiometry
physical entity: urea
stoichiometric coefficient: 1.0

Ureidoglycolate dehydrogenase
type: ProteinReference
xref: P02820
comment: ENTITY_REFERENCE_NOTES=Long Name: Ureidoglycolate dehydrogenase Synonym: Synonym not specified Accession: P02820
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Allantoin degradation.PROTEIN.GENERIC.Ureidoglycolate_br_dehydrogenase
member entity reference: Ureidoglycolate dehydrogenase (NAD(+))

uniprot O32137 38
type: UnificationXref
id: O32137
db: uniprot

uniprot P25335 25
type: UnificationXref
id: P25335
db: uniprot

PARTICIPANT STOICHIOMETRY r2 56
type: Stoichiometry
physical entity: H2O
stoichiometric coefficient: 1.0

2-hydroxy-3-oxopropionate reductase
type: ProteinReference
xref: uniprot P0ABQ2 50
organism: Escherichia coli

Glycerate kinase
type: ProteinReference
xref: uniprot P42100 4
organism: Bacillus subtilis

NADP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Tartronate semi-aldehyde dehydrogenase
type: Protein
entity reference: Tartronate semi-aldehyde dehydrogenase
comment: SPECIES_TYPE=PROTEIN

Escherichia coli
type: BioSource
xref: ncbitaxon 83333 3

Danio rerio
type: BioSource
xref: ncbitaxon 7955 32

CO2
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

urea
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Allantoicase
type: ProteinReference
xref: uniprot Q640T1 27
organism: Xenopus tropicalis

Glycerate 2-kinase
type: ProteinReference
xref: uniprot P23524 2
organism: Escherichia coli

ATP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Pseudomonas aeruginosa
type: BioSource
xref: ncbitaxon 208964 16

STATE_TRANSITION_LEFT__NADP-_Ureidoglycolate-RIGHT__NADPH-_oxalureate-_r3
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 54
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 52
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 53
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 55
left: Ureidoglycolate
left: NADP
interaction type: STATE_TRANSITION
right: NADPH
right: oxalureate

ncbitaxon 100226 8
type: UnificationXref
id: 100226
db: ncbitaxon

uniprot Q640T1 27
type: UnificationXref
id: Q640T1
db: uniprot

ncbitaxon 284812 10
type: UnificationXref
id: 284812
db: ncbitaxon

ncbitaxon 243230 47
type: UnificationXref
id: 243230
db: ncbitaxon

uniprot Q09913 26
type: UnificationXref
id: Q09913
db: uniprot

ncbitaxon 7955 32
type: UnificationXref
id: 7955
db: ncbitaxon

uniprot P77364 6
type: UnificationXref
id: P77364
db: uniprot

Probable allantoicase
type: ProteinReference
xref: uniprot Q9JHX6 35
organism: Mus musculus