Vascular endothelial growth factor receptor 2
Phosphatidylinositol 3-kinase catalytic subunit type 3
ENTITY_REFERENCE_NOTES=Long Name: c-Fos Transcription Factor Synonym: Oncogene FOS,v-Fos FBJ Murine Osteosarcoma Viral Oncogene Homolog Accession: P00235
ENTITY_REFERENCE_NOTES=Long Name: Hypoxia Inducible Factor-1 Synonym: MOP1,Member of PAS Superfamily 1 Accession: P00214
Neurogenic locus notch homolog protein 2
SOS Ras/Rac guanine nucleotide exchange factor 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
ENTITY_REFERENCE_NOTES=Long Name: Phospholiase A2 Synonym: CPLA2,PLA2 Accession: P00227
Non-specific serine/threonine protein kinase
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit
A-Raf proto-oncogene, serine/threonine kinase
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma
ENTITY_REFERENCE_NOTES=Long Name: c-Jun Transcription Factor Synonym: AP-1,Activator Protein 1,Oncogene Jun,v-Jun Avian Sarcoma Virus 17 Oncogene Homolog Accession: P00220
CRK like proto-oncogene, adaptor protein
CBF1, Suppressor of Hairless, Lag-1 Transcription Factor Family
ENTITY_REFERENCE_NOTES=Long Name: CBF1, Suppressor of Hairless, Lag-1 Transcription Factor Family Synonym: C Promoter-Binding Factor 1,CBF1,IGKJRB,Immunoglobulin Kappa J Region Recombination Signal-Binding Protein,RBPJK,RBPSUH,Recombination Signal-Binding Protein 1 for J-Kappa,Recombination Signal-Binding Protein Suppressor of Hairless Accession: P00233
Phosphatidylinositol 3-kinase regulatory subunit gamma
Recombining binding protein suppressor of hairless
Phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide (Predicted), isoform CRA_a
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
ENTITY_REFERENCE_NOTES=Long Name: Beta-catenin Synonym: Beta,CTNNB,Cadherin-Associated Protein Accession: P00187
Proto-oncogene tyrosine-protein kinase Src
Transforming growth factor beta 1 induced transcript 1
Platelet-derived growth factor alpha polypeptide a
Heat shock protein family B (small) member 2
Recombining binding protein suppressor of hairless-like protein
Raf-1 proto-oncogene, serine/threonine kinase
ENTITY_REFERENCE_NOTES=Long Name: Src Kinase Synonym: Avian Sarcoma Viral Oncogene,Src Oncogene Accession: P00184
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Platelet-derived growth factor receptor beta
ENTITY_REFERENCE_NOTES=Long Name: Crk oncogene Synonym: CRKII Accession: P00207
Signal transducer and activator of transcription
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma
ETS proto-oncogene 1, transcription factor
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
ENTITY_REFERENCE_NOTES=Long Name: Vascular Endothelial Growth Factor Synonym: VEGF-A Accession: P00241
SOS Ras/Rho guanine nucleotide exchange factor 2
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Receptor-type tyrosine-protein phosphatase beta
ENTITY_REFERENCE_NOTES=Long Name: Adenomatous Polyposis of the Colon Synonym: FAP,FPC,Familial Adenomatous Polyposis,Familial Polyposis of the Colon Accession: P00195
Signal transducer and activator of transcription 3
Baculoviral IAP repeat-containing protein 5
ENTITY_REFERENCE_NOTES=Long Name: Focal Adhesion Kinase Synonym: Cytoplasmic Protein-Tyrosine Kinase,FAK1,Focal Adhesion Kinase 1,PTK2 Accession: P00209
B-Raf proto-oncogene, serine/threonine kinase
Signal transducers and activators of transcription 3
ENTITY_REFERENCE_NOTES=Long Name: Signal Transducer and Activator of Transcription 3 Synonym: APRF,Acute-Phase Response Factor Accession: P00217
Fibroblast growth factor receptor substrate 2
RAC-alpha serine/threonine-protein kinase
RAC-beta serine/threonine-protein kinase
ENTITY_REFERENCE_NOTES=Long Name: Extracellular regulated kinase Synonym: JNK-Activated Kinase1,JNKK1,MAP2K4,MAPK/ERK Kinase 4,MAPKK4,MEK4,MKK4,Mitogen-Activated ProteinKinase Kinase 4,PRKMK4,Protein Kinase, Mitogen-Activated, Kinase 4,SAPK/ERK Kinase 1,SEK1,SERK1 Accession: P00203
ENTITY_REFERENCE_NOTES=Long Name: Tissue Factor Synonym: Coagulation Factor III,F3,Tissue Thromboplastin Accession: P00191
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Phosphatidylinositol 3-kinase regulatory subunit alpha
ENTITY_REFERENCE_NOTES=Long Name: Tie-2 Synonym: TEK,TEK Tyrosine Kinase Accession: P00247
V-crk avian sarcoma virus CT10 oncogene homolog
Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
RAS p21 protein activator (GTPase activating protein) 1
Platelet-derived growth factor subunit B
Phosphatidylinositol 3-kinase regulatory subunit beta
Nuclear receptor subfamily 1 group I member 2
Platelet-derived growth factor receptor alpha
Wingless-type MMTV integration site family member
ENTITY_REFERENCE_NOTES=Long Name: Wingless-Type MMTV Integration Site Family Synonym: Wnt Accession: P00206
Phosphatidylinositol 3-kinase VPS34-like
ENTITY_REFERENCE_NOTES=Long Name: Phosphatidylinositol 3-Kinase Synonym: PI(3)K Accession: P00236
Neuronal proto-oncogene tyrosine-protein kinase Src
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
Platelet-derived growth factor subunit A
Vascular Endothelial Protein Tyrosine Phosphatase
ENTITY_REFERENCE_NOTES=Long Name: Vascular Endothelial Protein Tyrosine Phosphatase Synonym: PTPRB,Protein-Tyrosine Phosphatase, Receptor-Type, Beta Accession: P00250
Phosphoinositide-3-kinase regulatory subunit 1
V-fos FBJ murine osteosarcoma viral oncogene homolog
SH2 homology domain containing transforming protein
ENTITY_REFERENCE_NOTES=Long Name: Src Homology Domain Containing Protein Synonym: SHC Transforming Protein Accession: P00183
MODEL_NOTES=Panther Pathway: P00005 This diagram represents several receptors and signaling pathways that have been identified as key mediators of angiogenesis, which is the process of blood vessel generation and maturation. Medline=11282421 Medline=11283723 Medline=11741095 Medline=12213597 Medline=12549854 Medline=12778165 Medline=12807741 Medline=12865906 Medline=13678960 Medline=14988924 PMID: 11282421 PMID: 11283723 PMID: 11741095 PMID: 12213597 PMID: 12549854 PMID: 12778165 PMID: 12807741 PMID: 12865906 PMID: 13678960 PMID: 14988924
ENTITY_REFERENCE_NOTES=Long Name: Frizzled Synonym: Synonym not specified Accession: P00189
ENTITY_REFERENCE_NOTES=Long Name: T-Cell Transcription Factor Synonym: TCF4,Transcription Factor 7-Like 2 Accession: P00242
Segment polarity protein dishevelled homolog DVL-1
Mitogen-activated protein kinase kinase 4A
RAF proto-oncogene serine/threonine-protein kinase
ENTITY_REFERENCE_NOTES=Long Name: p21-Activated Kinase Synonym: PAK Accession: P00249
V-crk avian sarcoma virus CT10 oncogene homolog-like
Segment polarity protein dishevelled homolog DVL-2
Dual specificity mitogen-activated protein kinase kinase 4
Glycogen synthase kinase-3 beta isoform 1
ENTITY_REFERENCE_NOTES=Long Name: Growth Factor Receptor-Bound Protein 2 Synonym: ASH Protein,Abundant SRC Homology,Adaptor Protein 2 Accession: P00234
ENTITY_REFERENCE_NOTES=Long Name: Angiopoietin-1 Synonym: Synonym not specified Accession: P00248
Phosphoinositide-3-kinase regulatory subunit 2
ENTITY_REFERENCE_NOTES=Long Name: Ras Synonym: H-Ras,K-Ras,N-Ras,p21 Accession: P00238
Ras guanine nucleotide exchange factor B
Segment polarity protein dishevelled homolog mig-5
Catenin (Cadherin-associated protein), beta 1, 88kDa
Dual specificity mitogen-activated protein kinase kinase 1
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Transforming growth factor beta-1-induced transcript 1 protein
Recombination signal-binding protein for immunoglobulin kappa J region-like
V-akt murine thymoma viral oncogene homolog 2,-like
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma plc-3
ENTITY_REFERENCE_NOTES=Long Name: c-Jun N-Terminal Kinase 1 Synonym: MAPK8,Mitogen-Activated Protein Kinase 8,PRKM8,Protein Kinase, Mitogen-Activated, 8,SAPK1,Stress-Activated Protein Kinase 1 Accession: P00221
ENTITY_REFERENCE_NOTES=Long Name: Heat-Shock Protein 27 Synonym: HSPB1 Accession: P00231
Endothelial-specific receptor tyrosine kinase
Hypoxia inducible factor 1 subunit alpha
Fos proto-oncogene, AP-1 transcription factor subunit
RAC-gamma serine/threonine-protein kinase
Mitogen-activated protein kinase-activated protein kinase 2
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
Baculoviral IAP repeat-containing protein 5.1
Neurogenic locus notch homolog protein 4
FBJ murine osteosarcoma viral oncogene homolog
Vascular endothelial growth factor receptor kdr-like
Website http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd
ENTITY_REFERENCE_NOTES=Long Name: Paxillin Synonym: PXN Accession: P00194
Platelet-derived growth factor A chain long form
ENTITY_REFERENCE_NOTES=Long Name: Phospholipase D Synonym: Synonym not specified Accession: P00204
ENTITY_REFERENCE_NOTES=Long Name: Fibroblast Growth Factor Synonym: ECGF,Endothelial Cell Growth Factor,HBGF,Heparin-Binding Growth Factor Accession: P00213
Fibroblast growth factor receptor substrate 3
Recombination signal-binding protein for immunoglobulin kappa J region
ENTITY_REFERENCE_NOTES=Long Name: Protein Kinase C Synonym: Synonym not specified Accession: P00219
ENTITY_REFERENCE_NOTES=Long Name: Growth Factor Receptor-Bound Protein 7 Synonym: Adaptor Protein 7 Accession: P00228
SHC (Src homology 2 domain containing) transforming protein 1
ENTITY_REFERENCE_NOTES=Long Name: Rho guanosine triphosphatase Synonym: RAS Homolog Gene Family,Rho,Rho GTPase Accession: P00254
ENTITY_REFERENCE_NOTES=Long Name: Baculoviral IAP Repeat-Containing Protein 5 Synonym: API4,Apoptosis inhibitor 4,BIRC5 Accession: P00198
ENTITY_REFERENCE_NOTES=Long Name: Mitogen Activated Protein Kinase Kinase Synonym: MAP kinase kinase,MAP/ERK Kinase,MAP2K,MAPKK,MKK,PRKMK,Protein Kinase, Mitogen-Activated, Kinase Accession: P00225
Mitogen-activated protein kinase kinase kinase 1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
ENTITY_REFERENCE_NOTES=Long Name: Fibroblast Growth Factor Receptor Substrate 2 Synonym: FRS2-Alpha,FRS2A,SNT,SNT1,SUC1-Associated Neurotrophic Factor Target 1 Accession: P00240
Segment polarity protein dishevelled homolog DVL-3
ENTITY_REFERENCE_NOTES=Long Name: Glycogen Synthase Kinase 3-beta Synonym: GSK3-beta Accession: P00211
ENTITY_REFERENCE_NOTES=Long Name: Sphingosine Kinase Synonym: SPHK Accession: P00229
-Ha-ras Harvey rat sarcoma viral oncogene homolog, like
ENTITY_REFERENCE_NOTES=Long Name: Protease Activated Receptor Synonym: NR1I2,Nuclear Receptor Subfamily 1, Group I, Member 2,PXR,Pregnane X Receptor,SXR,Steroid and Xenobiotic Receptor Accession: P00192
Dual specificity mitogen-activated protein kinase kinase 2
Recombination signal binding protein for immunoglobulin kappa J region
ENTITY_REFERENCE_NOTES=Long Name: Cytosolic Phospholipase A2 Synonym: PLA2 Accession: P00251
ENTITY_REFERENCE_NOTES=Long Name: Nck Adaptor Protein Synonym: Synonym not specified Accession: P00215
ENTITY_REFERENCE_NOTES=Long Name: Delta Synonym: Dll,JAG,JAGL,Jagged,Ser,Serrate Accession: P00226
Vascular Endothelial Growth Factor Receptor-2
ENTITY_REFERENCE_NOTES=Long Name: Vascular Endothelial Growth Factor Receptor-2 Synonym: FLK1,KDR,Kinase Insert Domain Receptor,Tyrosine Kinase Growth Factor Receptor Accession: P00222
ENTITY_REFERENCE_NOTES=Long Name: Ephrin Synonym: EFL,EFN,EPH-Related Receptor Tyrosine Kinase Ligand,EPLG,LERK,Ligand of EPH-Related Kinase Accession: P00239
ENTITY_REFERENCE_NOTES=Long Name: GTPase-Activating Protein Synonym: Guanosine Triphosphatase-Activating Protein,RAS p21 Protein Activator 1,RASA1,RASGAP Accession: P00205
ENTITY_REFERENCE_NOTES=Long Name: Son of Sevenless, Drosophila, Homolog 1 Synonym: SOS1 Guanine Nucleotide Exchange Factor Accession: P00193
ENTITY_REFERENCE_NOTES=Long Name: p38 Mitogen-Activated Protein Kinase Synonym: CSAID-Binding Protein1,CSBP1,Cytokine-Suppressive Anti-inflammatory Drug-Binding Protein 1,MAPK14,MXI2,Mitogen-Activated Protein Kinase 14,RK,SAPK2A,Stress-Activated Protein Kinase 2A,p38,p38 MAP Kinase,p38-Alpha Accession: P00182
ENTITY_REFERENCE_NOTES=Long Name: Docking Protein-R Synonym: Synonym not specified Accession: P00180
ENTITY_REFERENCE_NOTES=Long Name: Fibroblast Growth Factor Receptor-1 Synonym: FGFR-1,FLG,FLT2,FMS-Like Gene,FMS-Like Tyrosine Kinase 2 Accession: P00186
Putative glycogen synthase kinase-3 homolog
ENTITY_REFERENCE_NOTES=Long Name: Platelet-Derived Growth Factor Receptor Synonym: PDGFRA,PDGFRB Accession: P00230
Neurogenic locus notch homolog protein 1
ENTITY_REFERENCE_NOTES=Long Name: Axis inhibitor 1 Synonym: Fused Accession: P00253
ENTITY_REFERENCE_NOTES=Long Name: Platelet-Derived Growth Factor Synonym: PDGFA,PDGFB,PDGFC,PDGFD Accession: P00224
Harvey rat sarcoma viral oncogene homolog
Mitogen-activated protein kinase-activated protein kinase 2 and 3
ENTITY_REFERENCE_NOTES=Long Name: Mitogen-Activated Protein Kinase-Activating Protein Kinase-2 and 3 Synonym: 3PK,MAPKAP Kinase 2/3,MAPKAP2/3 Accession: P00244
ENTITY_REFERENCE_NOTES=Long Name: Phospholipase C-gamma Synonym: PLC1,PLC148,PLCG1,Phospholipase C-148 Accession: P00256
ENTITY_REFERENCE_NOTES=Long Name: endothelial nitric oxide synthase Synonym: NOS3,Nitric Oxide Synthase 3,eNOS Accession: P00210
Raf homolog serine/threonine-protein kinase Raf
Phosphoinositide-3-kinase regulatory subunit 3
v-Ets Avian Erythroblastosis Virus E26 Oncogene Homolog 1
ENTITY_REFERENCE_NOTES=Long Name: v-Ets Avian Erythroblastosis Virus E26 Oncogene Homolog 1 Synonym: Ets1 Oncogene Accession: P00188
ENTITY_REFERENCE_NOTES=Long Name: Protein Kinase B Synonym: Oncogene Akt,PKB,Rac serine/threonine kinase Accession: P00223
Signal transducer and activator of transcription 1-alpha/beta
Ras guanine nucleotide exchange factor R
Signal transducer and activator of transcription 1
Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
Mitogen-activated protein kinase kinase 4
Hypoxia inducible factor 1, alpha subunit (Basic helix-loop-helix transcription factor)
ENTITY_REFERENCE_NOTES=Long Name: Raf Oncogene Synonym: CRAF,Oncogene MIL,Raf,Transforming Replication-Defective Murine Retrovirus 3611-MSV,v-Raf-1 Murine Leukemia Viral Oncogene Homolog Accession: P00243
Ras guanine nucleotide exchange factor A
Mitogen-activated protein kinase (Fragment)
ENTITY_REFERENCE_ID_DESC=Angiogenesis.PROTEIN.GENERIC.Caspase 9
ENTITY_REFERENCE_NOTES=Long Name: Caspase 9 Synonym: APAF3,Apoptotic Protease Activating Factor 3 Accession: P00216
ENTITY_REFERENCE_NOTES=Long Name: Mitogen-Activated Kinase Kinase Kinase 1 Synonym: MAP/ERK Kinase Kinase 1,MAP3K1,MAPKKK1,MEK kinase Accession: P00208
ENTITY_REFERENCE_NOTES=Long Name: Frizzled-Related Protein Synonym: Frzb,SARP,SFRP,Secreted Apoptosis-Related Protein,Secreted Frizzled-Related Protein Accession: P00237
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
ENTITY_REFERENCE_NOTES=Long Name: Ras GTPase-Activating Protein Synonym: GAP,GTPase-Activating Protein,Guanosine Triphosphatase-Activating Protein,RAS p21 Protein Activator 1,RASA1 Accession: P00190
ENTITY_REFERENCE_NOTES=Long Name: Shc-like protein Synonym: Shc Adaptor Homolog Accession: P00202
ENTITY_REFERENCE_NOTES=Long Name: Janus Kinase 1 Synonym: Synonym not specified Accession: P00185
EPH-related receptor tyrosine kinase ligand 2
ENTITY_REFERENCE_NOTES=Long Name: VEGFR-Associated Protein Synonym: SH2 Domain Protein 2A,SH2D2A,T-Cell SH2 Domain Containing Adaptor Protein,TSAD,VRAP Accession: P00196
ENTITY_REFERENCE_NOTES=Long Name: Dishelvelled Synonym: Dvl Accession: P00200
MAP kinase-activated protein kinase mak-2
Raf homolog serine/threonine-protein kinase
ENTITY_REFERENCE_NOTES=Long Name: c-Jun N-terminal Kinase Kinase 1 Synonym: MAP2K4,MAPK/ERK Kinase 4,MAPKK4,MEK4,MKK4,Mitogen-Activated Protein Kinase Kinase 4,PRKMK4,Protein Kinase, Mitogen-Activated, Kinase 4,SAPK/ERK Kinase 1,SEK1,SERK1 Accession: P00199
Ras-related C3 botulinum toxin substrate
ENTITY_REFERENCE_NOTES=Long Name: Rho GTPase Synonym: CDC42,Cell Division Cycle 42 Accession: P00245
Signal transducers and activators of transcription 1
ENTITY_REFERENCE_NOTES=Long Name: Signal Transducer and Activator of Transcription 1 Synonym: Synonym not specified Accession: P00218
ENTITY_REFERENCE_NOTES=Long Name: Angiopoietin-2 Synonym: Synonym not specified Accession: P00246
ENTITY_REFERENCE_NOTES=Long Name: Factor VIIa Synonym: Coagulation Factor VII Accession: P00201
Jun proto-oncogene, AP-1 transcription factor subunit
Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 1
ENTITY_REFERENCE_NOTES=Long Name: Growth Factor Receptor-Bound Protein 14 Synonym: Adaptor Protein 14 Accession: P00197
Ras guanine nucleotide exchange factor Y