uniprot Q9HAV0 267
type: UnificationXref
id: Q9HAV0
db: uniprot

uniprot P54313 209
type: UnificationXref
id: P54313
db: uniprot

uniprot E1C795 124
type: UnificationXref
id: E1C795
db: uniprot

uniprot F6XVE6 151
type: UnificationXref
id: F6XVE6
db: uniprot

uniprot F7FXA9 169
type: UnificationXref
id: F7FXA9
db: uniprot

uniprot H2RCB8 43
type: UnificationXref
id: H2RCB8
db: uniprot

Neuronal synaptobrevin, isoform J
type: ProteinReference
xref: PTHR45701:SF3
xref: uniprot M9PE71 44
organism: Drosophila melanogaster

Vesicle associated membrane protein 8
type: ProteinReference
xref: uniprot A0A2I3SR99 10
xref: PTHR45701:SF7
organism: Pan troglodytes

SNARE COMPLEX
type: Protein
entity reference: SNARE COMPLEX
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

Synaptosomal-associated protein
type: ProteinReference
xref: PTHR19305:SF4
xref: uniprot A0A1D5QYR9 9
organism: Macaca mulatta

uniprot F1LQT1 279
type: UnificationXref
id: F1LQT1
db: uniprot

uniprot R4GKD1 271
type: UnificationXref
id: R4GKD1
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q5ZJ03 242
organism: Gallus gallus

uniprot F6Z5I2 35
type: UnificationXref
id: F6Z5I2
db: uniprot

uniprot P33328 59
type: UnificationXref
id: P33328
db: uniprot

Syntaxin-3
type: ProteinReference
xref: PTHR19957:SF34
xref: uniprot Q64704 89
organism: Mus musculus

Sympathetic Neuron c9
type: CellularLocationVocabulary
comment: Sympathetic Neuron

uniprot G3V8K2 175
type: UnificationXref
id: G3V8K2
db: uniprot

uniprot F6UBJ8 27
type: UnificationXref
id: F6UBJ8
db: uniprot

uniprot Q5BH99 237
type: UnificationXref
id: Q5BH99
db: uniprot

thermogenesis
type: Pathway

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot A4IFL6 112
organism: Bos taurus

uniprot Q2KJD2 80
type: UnificationXref
id: Q2KJD2
db: uniprot

GDP s3 sa3 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: GDP
stoichiometric coefficient: 1.0

uniprot E2R9G5 127
type: UnificationXref
id: E2R9G5
db: uniprot

Adenylate cyclase type 2
type: ProteinReference
xref: uniprot Q08462 288
xref: PTHR45627:SF6
organism: Homo sapiens

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
type: ProteinReference
xref: uniprot F7FXA9 169
organism: Macaca mulatta

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
type: ProteinReference
xref: uniprot P63212 220
organism: Bos taurus

uniprot E2RHY4 129
type: UnificationXref
id: E2RHY4
db: uniprot

uniprot G5EEN8 39
type: UnificationXref
id: G5EEN8
db: uniprot

uniprot P51828 286
type: UnificationXref
id: P51828
db: uniprot

uniprot Q28H40 234
type: UnificationXref
id: Q28H40
db: uniprot

Guanine nucleotide-binding protein subunit beta-4
type: ProteinReference
xref: uniprot P29387 195
organism: Mus musculus

AC
type: Protein
entity reference: AC
feature: ACTIVE 291
cellular location: cytosol
comment: SPECIES_TYPE=PROTEIN

Mus musculus
type: BioSource
xref: ncbitaxon 10090 50

Uncharacterized protein
type: ProteinReference
xref: PTHR45701:SF6
xref: uniprot F6XYX9 33
organism: Monodelphis domestica

uniprot O95721 54
type: UnificationXref
id: O95721
db: uniprot

Synaptosomal-associated protein
type: ProteinReference
xref: PTHR19305:SF14
xref: uniprot F5HMS4 23
organism: Anopheles gambiae

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot H2QZN8 181
organism: Pan troglodytes

Gnb2 protein
type: ProteinReference
xref: uniprot Q5BJ11 238
organism: Danio rerio

Saccharomyces cerevisiae
type: BioSource
xref: ncbitaxon 559292 58

ncbitaxon 9258 32
type: UnificationXref
id: 9258
db: ncbitaxon

Drosophila melanogaster
type: BioSource
xref: ncbitaxon 7227 45

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
type: ProteinReference
xref: uniprot Q61011 243
organism: Mus musculus

Uncharacterized protein
type: ProteinReference
xref: PTHR19957:SF34
xref: uniprot H2Q3R5 40
organism: Pan troglodytes

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
type: ProteinReference
xref: uniprot P62879 215
organism: Homo sapiens

PTHR19305:SF14
type: RelationshipXref
id: PTHR19305:SF14
db: PANTHER Family
relationship type: By Homology

MODULATION
type: Control
xref: MODULATION
controlled: lipolysis
controller: cAMP

uniprot A0A1D5RHE7 278
type: UnificationXref
id: A0A1D5RHE7
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
type: ProteinReference
xref: uniprot P62874 214
organism: Mus musculus

ncbitaxon 367110 141
type: UnificationXref
id: 367110
db: ncbitaxon

uniprot Q15KE4 231
type: UnificationXref
id: Q15KE4
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
type: ProteinReference
xref: uniprot P62872 212
organism: Canis lupus familiaris

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
type: ProteinReference
xref: uniprot P62873 213
organism: Homo sapiens

Guanine nucleotide-binding protein subunit beta-5
type: ProteinReference
xref: uniprot P62881 217
organism: Mus musculus

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
type: ProteinReference
xref: uniprot P62880 216
organism: Mus musculus

PTHR10218:SF212
type: RelationshipXref
id: PTHR10218:SF212
db: PANTHER Family
relationship type: By Homology

GTP s1 sa1 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: GTP
stoichiometric coefficient: 1.0

uniprot Q90Z40 264
type: UnificationXref
id: Q90Z40
db: uniprot

uniprot A0A3Q1NGS8 110
type: UnificationXref
id: A0A3Q1NGS8
db: uniprot

GDP
type: SmallMolecule
feature: COMPLEX PARTICIPANT BINDING FEATURE s6 sa6 307
cellular location: cytosol
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot O14775 187
type: UnificationXref
id: O14775
db: uniprot

uniprot P54311 208
type: UnificationXref
id: P54311
db: uniprot

ncbitaxon 44689 199
type: UnificationXref
id: 44689
db: ncbitaxon

Synaptosomal-associated protein 29
type: ProteinReference
xref: PTHR19305:SF9
xref: uniprot F6UFJ7 29
organism: Macaca mulatta

NE s9 sa9 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: NE
stoichiometric coefficient: 1.0

uniprot Q9CXP8 265
type: UnificationXref
id: Q9CXP8
db: uniprot

AGAP001506-PA
type: ProteinReference
xref: uniprot Q7PXP3 256
organism: Anopheles gambiae

uniprot F6UFJ7 29
type: UnificationXref
id: F6UFJ7
db: uniprot

Complex (GDP/G-Protein/_brBetasub_3/NE)
type: Complex
component stoichiometry: NE s9 sa9 STOICHIOMETRY ID COMPLEX
component stoichiometry: GDP s6 sa6 STOICHIOMETRY ID COMPLEX
component stoichiometry: Beta3 s8 sa8 STOICHIOMETRY ID COMPLEX
component stoichiometry: G Protein s7 sa7 STOICHIOMETRY ID COMPLEX
component: G-Protein
component: NE
component: Beta3
component: GDP
feature: COMPLEX BINDING FEATURE s38 a53 306
feature: COMPLEX BINDING FEATURE s38 a53 310
feature: COMPLEX BINDING FEATURE s38 a53 312
feature: COMPLEX BINDING FEATURE s38 a53 308
cellular location: cytosol

Neurospora crassa
type: BioSource
xref: ncbitaxon 367110 141

uniprot P38405 200
type: UnificationXref
id: P38405
db: uniprot

uniprot P29829 196
type: UnificationXref
id: P29829
db: uniprot

uniprot Q05337 228
type: UnificationXref
id: Q05337
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
type: ProteinReference
xref: uniprot P62871 211
organism: Bos taurus

PTHR10218:SF320
type: RelationshipXref
id: PTHR10218:SF320
db: PANTHER Family
relationship type: By Homology

Adenylate cyclase
type: ProteinReference
xref: uniprot F1LQT1 279
xref: PTHR45627:SF9
organism: Rattus norvegicus

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
type: ProteinReference
xref: uniprot Q61016 244
organism: Mus musculus

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
type: ProteinReference
xref: uniprot Q61017 245
organism: Mus musculus

uniprot F7ASR8 157
type: UnificationXref
id: F7ASR8
db: uniprot

uniprot F6ZDB2 155
type: UnificationXref
id: F6ZDB2
db: uniprot

ncbitaxon 3702 99
type: UnificationXref
id: 3702
db: ncbitaxon

G protein subunit alpha L
type: ProteinReference
xref: uniprot A0A2I3SJ53 107
organism: Pan troglodytes

uniprot F6YZA3 154
type: UnificationXref
id: F6YZA3
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
type: ProteinReference
xref: uniprot F7CTP1 161
organism: Macaca mulatta

Synaptosomal-associated protein 25
type: ProteinReference
xref: PTHR19305:SF5
xref: uniprot P60879 64
organism: Mus musculus

uniprot E2RGI5 128
type: UnificationXref
id: E2RGI5
db: uniprot

Synaptosomal-associated protein 25
type: ProteinReference
xref: uniprot P60878 62
xref: PTHR19305:SF5
organism: Gallus gallus

Synaptosomal-associated protein 29
type: ProteinReference
xref: uniprot Q9Z2P6 106
xref: PTHR19305:SF9
organism: Rattus norvegicus

Vesicle-associated membrane protein 8
type: ProteinReference
xref: uniprot Q9WUF4 105
xref: PTHR45701:SF7
organism: Rattus norvegicus

Synaptosomal-associated protein 25
type: ProteinReference
xref: uniprot Q5R1X1 84
xref: PTHR19305:SF5
organism: Pan troglodytes

Putative synaptobrevin homologue SNC1/2 (Eurofung)
type: ProteinReference
xref: uniprot Q5ASG1 82
organism: Emericella nidulans

Guanine nucleotide binding protein, beta 3
type: ProteinReference
xref: uniprot Q5XGD8 241
organism: Xenopus tropicalis

uniprot P60878 62
type: UnificationXref
id: P60878
db: uniprot

Synaptosomal-associated protein 25
type: ProteinReference
xref: PTHR19305:SF5
xref: uniprot P60877 61
organism: Macaca mulatta

uniprot H2Q995 41
type: UnificationXref
id: H2Q995
db: uniprot

uniprot Q61017 245
type: UnificationXref
id: Q61017
db: uniprot

synaptic vesicle
type: CellularLocationVocabulary
xref: GO GO:0008021 2

uniprot P36975 60
type: UnificationXref
id: P36975
db: uniprot

Synaptosomal-associated protein 25
type: ProteinReference
xref: uniprot P60880 65
xref: PTHR19305:SF5
organism: Homo sapiens

Pan troglodytes
type: BioSource
xref: ncbitaxon 9598 11

uniprot F7CXD0 162
type: UnificationXref
id: F7CXD0
db: uniprot

HETERODIMER_ASSOCIATION_LEFT__NE-_Complex__GDP_G_Protein__brBetasub_3_-RIGHT__Complex__GDP_G_Protein__brBetasub_3_NE_-_re18
type: ComplexAssembly
spontaneous: true
conversion direction: LEFT_TO_RIGHT
xref: HETERODIMER ASSOCIATION
participant stoichiometry: PARTICIPANT STOICHIOMETRY re18 326
participant stoichiometry: PARTICIPANT STOICHIOMETRY re18 325
participant stoichiometry: PARTICIPANT STOICHIOMETRY re18 327
left: Complex (GDP/G-Protein/_brBetasub_3)
left: NE
interaction type: HETERODIMER_ASSOCIATION
right: Complex (GDP/G-Protein/_brBetasub_3/NE)

Xenopus tropicalis
type: BioSource
xref: ncbitaxon 8364 28

uniprot Q9WUF4 105
type: UnificationXref
id: Q9WUF4
db: uniprot

Vesicle-associated membrane protein 3
type: ProteinReference
xref: PTHR45701:SF6
xref: uniprot Q2KJD2 80
organism: Bos taurus

uniprot Q6DGZ5 247
type: UnificationXref
id: Q6DGZ5
db: uniprot

uniprot P60877 61
type: UnificationXref
id: P60877
db: uniprot

uniprot P63217 225
type: UnificationXref
id: P63217
db: uniprot

TRIGGER
type: RelationshipTypeVocabulary

uniprot P63216 224
type: UnificationXref
id: P63216
db: uniprot

uniprot F7CFG8 160
type: UnificationXref
id: F7CFG8
db: uniprot

GTP
type: SmallMolecule
feature: COMPLEX PARTICIPANT BINDING FEATURE s1 sa1 299
cellular location: cytosol
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q61011 243
type: UnificationXref
id: Q61011
db: uniprot

uniprot Q5TZ66 85
type: UnificationXref
id: Q5TZ66
db: uniprot

uniprot Q9W3J1 270
type: UnificationXref
id: Q9W3J1
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
type: ProteinReference
xref: uniprot O14610 186
organism: Homo sapiens

Vesicle-associated membrane protein 2
type: ProteinReference
xref: uniprot P63044 71
xref: PTHR45701:SF5
organism: Mus musculus

Vesicle-associated membrane protein 2
type: ProteinReference
xref: PTHR45701:SF5
xref: uniprot P63045 72
organism: Rattus norvegicus

G-Protein
type: Protein
entity reference: G-Protein
feature: COMPLEX PARTICIPANT BINDING FEATURE s2 sa2 301
cellular location: cytosol
comment: SPECIES_TYPE=PROTEIN

Synaptobrevin-1
type: ProteinReference
xref: PTHR45701:SF3
xref: uniprot O02495 48
organism: Caenorhabditis elegans

Guanine nucleotide-binding protein subunit beta
type: ProteinReference
xref: uniprot P49177 202
organism: Arabidopsis thaliana

uniprot A0A1D5QIS2 8
type: UnificationXref
id: A0A1D5QIS2
db: uniprot

Guanine nucleotide-binding protein subunit beta-5a
type: ProteinReference
xref: uniprot A1L271 111
organism: Danio rerio

Uncharacterized protein
type: ProteinReference
xref: uniprot C3ZSF0 119
organism: Branchiostoma floridae

P04447
type: UnificationXref
id: P04447
db: PANTHER Pathway Component

uniprot P50151 204
type: UnificationXref
id: P50151
db: uniprot

ncbitaxon 665079 116
type: UnificationXref
id: 665079
db: ncbitaxon

uniprot P63219 227
type: UnificationXref
id: P63219
db: uniprot

Vesicle-associated membrane protein 8 (Endobrevin)
type: ProteinReference
xref: uniprot Q7ZUC1 93
xref: PTHR45701:SF7
organism: Danio rerio

P04449
type: UnificationXref
id: P04449
db: PANTHER Pathway Component

P04448
type: UnificationXref
id: P04448
db: PANTHER Pathway Component

uniprot P83351 73
type: UnificationXref
id: P83351
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
type: ProteinReference
xref: uniprot P11017 189
organism: Bos taurus

P04450
type: UnificationXref
id: P04450
db: PANTHER Pathway Component

uniprot O60262 188
type: UnificationXref
id: O60262
db: uniprot

Vesicle-associated membrane protein 2
type: ProteinReference
xref: uniprot P63027 70
xref: PTHR45701:SF5
organism: Homo sapiens

uniprot C3ZSF0 119
type: UnificationXref
id: C3ZSF0
db: uniprot

Vesicle-associated membrane protein 2
type: ProteinReference
xref: uniprot P63026 69
xref: PTHR45701:SF5
organism: Bos taurus

uniprot F6XHP0 150
type: UnificationXref
id: F6XHP0
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F7H6T7 173
organism: Macaca mulatta

Beta3 s5 sa5 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Beta3
stoichiometric coefficient: 1.0

uniprot Q15836 77
type: UnificationXref
id: Q15836
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F7CB49 159
organism: Monodelphis domestica

Vesicle-associated membrane protein 3
type: ProteinReference
xref: PTHR45701:SF6
xref: uniprot P63024 66
organism: Mus musculus

uniprot Q9DAS9 266
type: UnificationXref
id: Q9DAS9
db: uniprot

Vesicle-associated membrane protein 3
type: ProteinReference
xref: PTHR45701:SF6
xref: uniprot P63025 67
organism: Rattus norvegicus

uniprot D3ZLD6 121
type: UnificationXref
id: D3ZLD6
db: uniprot

Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas
type: ProteinReference
xref: PTHR10218:SF320
xref: uniprot Q6R0H7 253
organism: Mus musculus

uniprot P63215 223
type: UnificationXref
id: P63215
db: uniprot

ncbitaxon 9606 47
type: UnificationXref
id: 9606
db: ncbitaxon

G protein subunit beta 1
type: ProteinReference
xref: uniprot F6PGC8 142
organism: Ornithorhynchus anatinus

Vesicle associated membrane protein 8
type: ProteinReference
xref: uniprot E2QUL2 19
xref: PTHR45701:SF7
organism: Canis lupus familiaris

uniprot E1BW98 123
type: UnificationXref
id: E1BW98
db: uniprot

uniprot Q6P025 249
type: UnificationXref
id: Q6P025
db: uniprot

uniprot Q3SZ98 236
type: UnificationXref
id: Q3SZ98
db: uniprot

uniprot H2R3A6 182
type: UnificationXref
id: H2R3A6
db: uniprot

Complex (GTP/G-Protein)
type: Complex
component stoichiometry: GTP s1 sa1 STOICHIOMETRY ID COMPLEX
component stoichiometry: G Protein s2 sa2 STOICHIOMETRY ID COMPLEX
component: GTP
component: G-Protein
feature: COMPLEX BINDING FEATURE s17 a15 298
feature: COMPLEX BINDING FEATURE s17 a15 300
feature: ACTIVE 291
cellular location: cytosol

Guanine nucleotide-binding protein beta subunit
type: ProteinReference
xref: uniprot F5HH30 140
organism: Neurospora crassa

Guanine nucleotide-binding protein G(olf) subunit alpha
type: ProteinReference
xref: uniprot Q8CGK7 263
organism: Mus musculus

uniprot E2RJB3 130
type: UnificationXref
id: E2RJB3
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
type: ProteinReference
xref: uniprot P43425 201
organism: Rattus norvegicus

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot E2R9G5 127
organism: Canis lupus familiaris

Vesicle-associated membrane protein 8
type: ProteinReference
xref: uniprot O70404 53
xref: PTHR45701:SF7
organism: Mus musculus

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot A4IGZ2 113
organism: Xenopus tropicalis

uniprot P26255 276
type: UnificationXref
id: P26255
db: uniprot

uniprot Q9ERB0 97
type: UnificationXref
id: Q9ERB0
db: uniprot

uniprot P50154 206
type: UnificationXref
id: P50154
db: uniprot

Guanine nucleotide-binding protein subunit beta-5
type: ProteinReference
xref: uniprot O14775 187
organism: Homo sapiens

VAMP2 isoform 3
type: ProteinReference
xref: uniprot H2RCB8 43
xref: PTHR45701:SF5
organism: Pan troglodytes

PARTICIPANT STOICHIOMETRY re18 325
type: Stoichiometry
physical entity: NE
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY re18 326
type: Stoichiometry
physical entity: Complex (GDP/G-Protein/_brBetasub_3)
stoichiometric coefficient: 1.0

eco ECO:0000250 6
type: UnificationXref
id: ECO:0000250
db: eco

Vesicle associated membrane protein 8
type: ProteinReference
xref: uniprot F6Z5I2 35
xref: PTHR45701:SF7
organism: Monodelphis domestica

PARTICIPANT STOICHIOMETRY re18 327
type: Stoichiometry
physical entity: Complex (GDP/G-Protein/_brBetasub_3/NE)
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY re19 320
type: Stoichiometry
physical entity: GTP
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY re19 322
type: Stoichiometry
physical entity: GDP
stoichiometric coefficient: 1.0

uniprot K7E376 185
type: UnificationXref
id: K7E376
db: uniprot

PARTICIPANT STOICHIOMETRY re19 321
type: Stoichiometry
physical entity: Complex (GDP/G-Protein/_brBetasub_3/NE)
stoichiometric coefficient: 1.0

ncbitaxon 214684 240
type: UnificationXref
id: 214684
db: ncbitaxon

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
type: ProteinReference
xref: uniprot Q28024 233
organism: Bos taurus

ncbitaxon 7739 120
type: UnificationXref
id: 7739
db: ncbitaxon

AC
type: ProteinReference
xref: P04450
standard name: adenylate cyclase
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: AC Synonym: adenylate cyclase,adenylate cyclase 2,adenylate cyclase 7,adenylyl cyclase Accession: P04450
comment: ENTITY_REFERENCE_ID_DESC=Beta3 adrenergic receptor signaling pathway.PROTEIN.GENERIC.AC
member entity reference: Adenylate cyclase
member entity reference: Adenylate cyclase type 7
member entity reference: Adenylate cyclase type 2

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F6XWE8 152
organism: Monodelphis domestica

uniprot P63045 72
type: UnificationXref
id: P63045
db: uniprot

PARTICIPANT STOICHIOMETRY re19 323
type: Stoichiometry
physical entity: Complex (Beta3/NE)
stoichiometric coefficient: 1.0

NE s11 sa11 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: NE
stoichiometric coefficient: 1.0

G-Protein
type: ProteinReference
xref: P04448
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Beta3 adrenergic receptor signaling pathway.PROTEIN.GENERIC.G-Protein
comment: ENTITY_REFERENCE_NOTES=
member entity reference: Guanine nucleotide-binding protein subunit gamma
member entity reference: Uncharacterized protein
member entity reference: Guanine nucleotide-binding protein subunit beta
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
member entity reference: G protein subunit beta 4
member entity reference: AGAP005913-PA
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
member entity reference: G-protein beta subunit
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
member entity reference: Guanine nucleotide-binding protein (G protein), alpha-activating activity polypeptide, olfactory type
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
member entity reference: Guanine nucleotide-binding protein subunit beta-4
member entity reference: AGAP005911-PA
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
member entity reference: Guanine nucleotide-binding protein subunit beta-5
member entity reference: Guanine nucleotide-binding protein subunit beta-2
member entity reference: Gnb2 protein
member entity reference: Guanine nucleotide-binding protein G(f) subunit alpha
member entity reference: Guanine nucleotide-binding protein subunit beta-1
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
member entity reference: G protein subunit beta 2
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
member entity reference: Guanine nucleotide-binding protein beta subunit
member entity reference: G protein subunit beta 1
member entity reference: G protein, Subunit Alpha
member entity reference: Guanine nucleotide-binding protein subunit beta-5a

G protein subunit beta 4
type: ProteinReference
xref: uniprot E2R2S8 126
organism: Canis lupus familiaris

PARTICIPANT STOICHIOMETRY re19 324
type: Stoichiometry
physical entity: Complex (GTP/G-Protein)
stoichiometric coefficient: 1.0

ncbitaxon 7955 86
type: UnificationXref
id: 7955
db: ncbitaxon

uniprot A0A3Q1M3D6 109
type: UnificationXref
id: A0A3Q1M3D6
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__ATP-RIGHT__cAMP-_re9
controller: AC

uniprot E2QUL2 19
type: UnificationXref
id: E2QUL2
db: uniprot

Synaptobrevin homolog 1
type: ProteinReference
xref: uniprot Q92356 94
organism: Schizosaccharomyces pombe

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot E2R2S3 125
organism: Canis lupus familiaris

eco ECO:0000305 16
type: UnificationXref
id: ECO:0000305
db: eco

uniprot P18489 55
type: UnificationXref
id: P18489
db: uniprot

uniprot Q5XGD8 241
type: UnificationXref
id: Q5XGD8
db: uniprot

uniprot O14610 186
type: UnificationXref
id: O14610
db: uniprot

AGAP005911-PA
type: ProteinReference
xref: uniprot Q7Q6D4 260
organism: Anopheles gambiae

MODULATION
type: RelationshipTypeVocabulary

AGAP005913-PA
type: ProteinReference
xref: uniprot Q7Q6D2 258
organism: Anopheles gambiae

AGAP005912-PA
type: ProteinReference
xref: uniprot Q7Q6D3 259
organism: Anopheles gambiae

uniprot Q9Z2P6 106
type: UnificationXref
id: Q9Z2P6
db: uniprot

uniprot P63218 226
type: UnificationXref
id: P63218
db: uniprot

Bos taurus
type: BioSource
xref: ncbitaxon 9913 13

ncbitaxon 9544 5
type: UnificationXref
id: 9544
db: ncbitaxon

Macaca mulatta
type: BioSource
xref: ncbitaxon 9544 5

uniprot F6PVT7 144
type: UnificationXref
id: F6PVT7
db: uniprot

uniprot Q28HP6 79
type: UnificationXref
id: Q28HP6
db: uniprot

ncbitaxon 6238 18
type: UnificationXref
id: 6238
db: ncbitaxon

Ornithorhynchus anatinus
type: BioSource
xref: ncbitaxon 9258 32

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot H2Q3W7 178
organism: Pan troglodytes

uniprot P60880 65
type: UnificationXref
id: P60880
db: uniprot

uniprot H2Q3W7 178
type: UnificationXref
id: H2Q3W7
db: uniprot

ncbitaxon 284812 95
type: UnificationXref
id: 284812
db: ncbitaxon

uniprot F1PJE5 137
type: UnificationXref
id: F1PJE5
db: uniprot

uniprot P23763 56
type: UnificationXref
id: P23763
db: uniprot

uniprot J9P702 183
type: UnificationXref
id: J9P702
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q28H40 234
organism: Xenopus tropicalis

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
type: ProteinReference
xref: uniprot P30671 197
organism: Bos taurus

Synaptosomal-associated protein 29
type: ProteinReference
xref: PTHR19305:SF9
xref: uniprot O95721 54
organism: Homo sapiens

uniprot Q5ASG1 82
type: UnificationXref
id: Q5ASG1
db: uniprot

uniprot F6V001 281
type: UnificationXref
id: F6V001
db: uniprot

G protein alpha s subunit
type: ProteinReference
xref: PTHR10218:SF212
xref: uniprot P20354 193
organism: Drosophila melanogaster

uniprot Q28024 233
type: UnificationXref
id: Q28024
db: uniprot

uniprot Q64704 89
type: UnificationXref
id: Q64704
db: uniprot

uniprot P63026 69
type: UnificationXref
id: P63026
db: uniprot

uniprot P50153 205
type: UnificationXref
id: P50153
db: uniprot

AGAP006521-PA
type: ProteinReference
xref: uniprot Q7Q5C3 257
organism: Anopheles gambiae

Ixodes scapularis
type: BioSource
xref: ncbitaxon 6945 118

uniprot P63025 67
type: UnificationXref
id: P63025
db: uniprot

uniprot K7ADQ0 284
type: UnificationXref
id: K7ADQ0
db: uniprot

uniprot Q5R1X1 84
type: UnificationXref
id: Q5R1X1
db: uniprot

DISSOCIATION
type: RelationshipTypeVocabulary

uniprot Q7Q5C3 257
type: UnificationXref
id: Q7Q5C3
db: uniprot

ncbitaxon 227321 83
type: UnificationXref
id: 227321
db: ncbitaxon

ncbitaxon 559292 58
type: UnificationXref
id: 559292
db: ncbitaxon

uniprot A7EDU2 115
type: UnificationXref
id: A7EDU2
db: uniprot

AC
type: Protein
entity reference: AC
cellular location: cytosol
comment: SPECIES_TYPE=PROTEIN

Guanine nucleotide-binding protein subunit beta
type: ProteinReference
xref: uniprot F1A421 133
organism: Dictyostelium purpureum

uniprot P17343 191
type: UnificationXref
id: P17343
db: uniprot

uniprot P30671 197
type: UnificationXref
id: P30671
db: uniprot

uniprot A0A2I3SJ53 107
type: UnificationXref
id: A0A2I3SJ53
db: uniprot

uniprot E2R2S8 126
type: UnificationXref
id: E2R2S8
db: uniprot

Adrenoceptor beta 3
type: ProteinReference
xref: PTHR24248:SF3
xref: uniprot H2R1M3 273
organism: Pan troglodytes

Canis lupus familiaris
type: BioSource
xref: ncbitaxon 9615 20

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
type: ProteinReference
xref: uniprot P50150 203
organism: Homo sapiens

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A3Q1NGS8 110
organism: Bos taurus

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
type: ProteinReference
xref: uniprot P50151 204
organism: Homo sapiens

G protein subunit beta 4
type: ProteinReference
xref: uniprot H2QNS5 180
organism: Pan troglodytes

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F7G7I9 171
organism: Ornithorhynchus anatinus

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
type: ProteinReference
xref: uniprot P50154 206
organism: Bos taurus

ncbitaxon 10090 50
type: UnificationXref
id: 10090
db: ncbitaxon

Uncharacterized protein
type: ProteinReference
xref: PTHR19957:SF34
xref: uniprot A0A3Q1LYB4 12
organism: Bos taurus

Adenylate cyclase type 2
type: ProteinReference
xref: PTHR45627:SF6
xref: uniprot Q80TL1 290
organism: Mus musculus

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
type: ProteinReference
xref: uniprot P50153 205
organism: Mus musculus

VAMP3 isoform 1
type: ProteinReference
xref: PTHR45701:SF6
xref: uniprot G2HIJ9 38
organism: Pan troglodytes

PTHR45701:SF10
type: RelationshipXref
id: PTHR45701:SF10
db: PANTHER Family
relationship type: By Homology

Uncharacterized protein
type: ProteinReference
xref: PTHR19957:SF34
xref: uniprot A0A1D5QDW1 4
organism: Macaca mulatta

GTP
type: SmallMolecule
cellular location: cytosol
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A3Q1M3D6 109
organism: Bos taurus

Synaptosomal-associated protein
type: ProteinReference
xref: uniprot E2R907 21
xref: PTHR19305:SF5
organism: Canis lupus familiaris

uniprot O00161 46
type: UnificationXref
id: O00161
db: uniprot

uniprot Q7KPV0 255
type: UnificationXref
id: Q7KPV0
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F7CFG8 160
organism: Monodelphis domestica

Gallus gallus
type: BioSource
xref: ncbitaxon 9031 63

uniprot A4IGZ2 113
type: UnificationXref
id: A4IGZ2
db: uniprot

uniprot F6SSS3 145
type: UnificationXref
id: F6SSS3
db: uniprot

G Protein s7 sa7 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: G-Protein
stoichiometric coefficient: 1.0

Uncharacterized protein
type: ProteinReference
xref: PTHR19957:SF34
xref: uniprot F6SED9 25
organism: Monodelphis domestica

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__AC-RIGHT__AC-_re17
controller: Complex (GTP/G-Protein)

Complex (Beta3/NE)
type: Complex
component stoichiometry: NE s11 sa11 STOICHIOMETRY ID COMPLEX
component stoichiometry: Beta3 s10 sa10 STOICHIOMETRY ID COMPLEX
component: Beta3
component: NE
feature: COMPLEX BINDING FEATURE s39 a54 302
feature: COMPLEX BINDING FEATURE s39 a54 304
cellular location: cytosol

ncbitaxon 7227 45
type: UnificationXref
id: 7227
db: ncbitaxon

uniprot Q3T0Y8 81
type: UnificationXref
id: Q3T0Y8
db: uniprot

Adenylate cyclase type 7
type: ProteinReference
xref: uniprot P51828 286
xref: PTHR45627:SF9
organism: Homo sapiens

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F7GI54 172
organism: Monodelphis domestica

Adenylate cyclase type 7
type: ProteinReference
xref: uniprot P51829 287
xref: PTHR45627:SF9
organism: Mus musculus

uniprot Q9VH76 103
type: UnificationXref
id: Q9VH76
db: uniprot

uniprot P16520 190
type: UnificationXref
id: P16520
db: uniprot

uniprot H2QZN8 181
type: UnificationXref
id: H2QZN8
db: uniprot

SNAP25 homologous protein SNAP33
type: ProteinReference
xref: uniprot Q9S7P9 101
organism: Arabidopsis thaliana

Synaptosomal-associated protein
type: ProteinReference
xref: PTHR19305:SF14
xref: uniprot Q9VH76 103
organism: Drosophila melanogaster

Uncharacterized protein
type: ProteinReference
xref: PTHR45701:SF6
xref: uniprot F6YMH2 34
organism: Macaca mulatta

uniprot Q9LMG8 98
type: UnificationXref
id: Q9LMG8
db: uniprot

STATE_TRANSITION
type: RelationshipTypeVocabulary

Gnb3 protein
type: ProteinReference
xref: uniprot Q6P025 249
organism: Danio rerio

uniprot P25962 275
type: UnificationXref
id: P25962
db: uniprot

Complex (GDP/G-Protein/_brBetasub_3)
type: Complex
component stoichiometry: Beta3 s5 sa5 STOICHIOMETRY ID COMPLEX
component stoichiometry: GDP s3 sa3 STOICHIOMETRY ID COMPLEX
component stoichiometry: G Protein s4 sa4 STOICHIOMETRY ID COMPLEX
component: G-Protein
component: Beta3
component: GDP
feature: COMPLEX BINDING FEATURE s35 a45 294
feature: COMPLEX BINDING FEATURE s35 a45 292
feature: COMPLEX BINDING FEATURE s35 a45 296
cellular location: cytosol

Adenylate cyclase
type: ProteinReference
xref: uniprot K7ADQ0 284
xref: PTHR45627:SF9
organism: Pan troglodytes

uniprot A8X8S6 17
type: UnificationXref
id: A8X8S6
db: uniprot

uniprot A0A3Q1LYB4 12
type: UnificationXref
id: A0A3Q1LYB4
db: uniprot

Vesicle-associated membrane protein 8
type: ProteinReference
xref: PTHR45701:SF7
xref: uniprot Q9BV40 96
organism: Homo sapiens

Uncharacterized protein
type: ProteinReference
xref: uniprot Q5KI86 239
organism: Cryptococcus neoformans

uniprot Q0VFC4 229
type: UnificationXref
id: Q0VFC4
db: uniprot

ncbitaxon 5786 134
type: UnificationXref
id: 5786
db: ncbitaxon

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot G3V6P8 174
organism: Rattus norvegicus

Guanine nucleotide binding protein, beta subunit
type: ProteinReference
xref: uniprot E9FUX0 131
organism: Daphnia pulex

uniprot F7G7I9 171
type: UnificationXref
id: F7G7I9
db: uniprot

uniprot Q5KI86 239
type: UnificationXref
id: Q5KI86
db: uniprot

uniprot F6XYX9 33
type: UnificationXref
id: F6XYX9
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F7A943 36
xref: PTHR45701:SF5
organism: Monodelphis domestica

Beta3 s10 sa10 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Beta3
stoichiometric coefficient: 1.0

Soluble NSF attachment protein 29
type: ProteinReference
xref: PTHR19305:SF9
xref: uniprot P83351 73
organism: Caenorhabditis elegans

G protein, Subunit Alpha
type: ProteinReference
xref: uniprot Q7KPV0 255
organism: Caenorhabditis elegans

uniprot F7H6T7 173
type: UnificationXref
id: F7H6T7
db: uniprot

G protein subunit beta 5
type: ProteinReference
xref: uniprot H2Q9G5 179
organism: Pan troglodytes

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
type: ProteinReference
xref: uniprot Q9UBI6 268
organism: Homo sapiens

Adenylate cyclase type 7
type: ProteinReference
xref: uniprot Q29450 289
xref: PTHR45627:SF9
organism: Bos taurus

PARTICIPANT STOICHIOMETRY re2 317
type: Stoichiometry
physical entity: NE
stoichiometric coefficient: 1.0

uniprot P11017 189
type: UnificationXref
id: P11017
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR10218:SF320
xref: uniprot F6PV18 143
organism: Macaca mulatta

PARTICIPANT STOICHIOMETRY re2 316
type: Stoichiometry
physical entity: NE
stoichiometric coefficient: 1.0

uniprot P63024 66
type: UnificationXref
id: P63024
db: uniprot

uniprot E2R907 21
type: UnificationXref
id: E2R907
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
type: ProteinReference
xref: uniprot P63219 227
organism: Rattus norvegicus

uniprot F6SED9 25
type: UnificationXref
id: F6SED9
db: uniprot

PTHR24248:SF3
type: RelationshipXref
id: PTHR24248:SF3
db: PANTHER Family
relationship type: By Homology

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
type: ProteinReference
xref: uniprot P63218 226
organism: Homo sapiens

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
type: ProteinReference
xref: uniprot P63217 225
organism: Bos taurus

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
type: ProteinReference
xref: uniprot P63216 224
organism: Mus musculus

Uncharacterized protein
type: ProteinReference
xref: uniprot F6PVT7 144
organism: Monodelphis domestica

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
type: ProteinReference
xref: uniprot P63215 223
organism: Homo sapiens

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
type: ProteinReference
xref: uniprot P63214 222
organism: Bos taurus

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
type: ProteinReference
xref: uniprot P63213 221
organism: Mus musculus

Caenorhabditis briggsae
type: BioSource
xref: ncbitaxon 6238 18

Uncharacterized protein
type: ProteinReference
xref: uniprot F6Y3N2 153
organism: Monodelphis domestica

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q15KE4 231
organism: Danio rerio

THO complex subunit, putative
type: ProteinReference
xref: uniprot B7Q3T6 117
organism: Ixodes scapularis

Caenorhabditis elegans
type: BioSource
xref: ncbitaxon 6239 15

ncbitaxon 8364 28
type: UnificationXref
id: 8364
db: ncbitaxon

Beta-3 adrenergic receptor
type: ProteinReference
xref: PTHR24248:SF3
xref: uniprot A0A3Q1MQZ8 272
organism: Bos taurus

uniprot F7G3J2 170
type: UnificationXref
id: F7G3J2
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot E1BS74 122
organism: Gallus gallus

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F6XHP0 150
organism: Macaca mulatta

Guanine nucleotide-binding protein subunit beta-2
type: ProteinReference
xref: uniprot P29829 196
organism: Drosophila melanogaster

ncbitaxon 10116 68
type: UnificationXref
id: 10116
db: ncbitaxon

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
type: ProteinReference
xref: uniprot Q9DAS9 266
organism: Mus musculus

ACTIVE 291
type: EntityFeature
comment: Active state

uniprot F7ERP8 166
type: UnificationXref
id: F7ERP8
db: uniprot

uniprot Q28524 277
type: UnificationXref
id: Q28524
db: uniprot

uniprot F7ES96 167
type: UnificationXref
id: F7ES96
db: uniprot

By Homology
type: RelationshipTypeVocabulary

uniprot P49177 202
type: UnificationXref
id: P49177
db: uniprot

Beta3
type: Protein
entity reference: Beta3
feature: COMPLEX PARTICIPANT BINDING FEATURE s10 sa10 303
cellular location: cytosol
comment: SPECIES_TYPE=PROTEIN

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F7F580 168
organism: Macaca mulatta

uniprot M9PE71 44
type: UnificationXref
id: M9PE71
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F7ASR8 157
organism: Macaca mulatta

uniprot P62873 213
type: UnificationXref
id: P62873
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
type: ProteinReference
xref: uniprot Q9CXP8 265
organism: Mus musculus

Guanine nucleotide-binding protein subunit beta-1
type: ProteinReference
xref: uniprot P26308 194
organism: Drosophila melanogaster

uniprot F6YMH2 34
type: UnificationXref
id: F6YMH2
db: uniprot

uniprot F6PGC8 142
type: UnificationXref
id: F6PGC8
db: uniprot

uniprot F2Z3T8 139
type: UnificationXref
id: F2Z3T8
db: uniprot

uniprot Q6DF43 246
type: UnificationXref
id: Q6DF43
db: uniprot

uniprot Q6PC54 90
type: UnificationXref
id: Q6PC54
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot E2RGI5 128
organism: Canis lupus familiaris

Uncharacterized protein
type: ProteinReference
xref: uniprot F7CXD0 162
organism: Monodelphis domestica

G-protein beta subunit
type: ProteinReference
xref: uniprot Q5BH99 237
organism: Emericella nidulans

uniprot H2Q9G5 179
type: UnificationXref
id: H2Q9G5
db: uniprot

uniprot E9FUX0 131
type: UnificationXref
id: E9FUX0
db: uniprot

Synaptosomal-associated protein
type: ProteinReference
xref: uniprot F6VM87 30
xref: PTHR19305:SF5
organism: Monodelphis domestica

Beta-3 adrenergic receptor
type: ProteinReference
xref: PTHR24248:SF3
xref: uniprot P13945 274
organism: Homo sapiens

Synaptobrevin
type: ProteinReference
xref: PTHR45701:SF10
xref: uniprot P18489 55
organism: Drosophila melanogaster

uniprot Q6DH55 248
type: UnificationXref
id: Q6DH55
db: uniprot

uniprot A0A2I3TUD1 108
type: UnificationXref
id: A0A2I3TUD1
db: uniprot

TRANSPORT
type: RelationshipTypeVocabulary

SNAP25 homologous protein SNAP29
type: ProteinReference
xref: uniprot Q9SD96 102
organism: Arabidopsis thaliana

uniprot H2PZA6 176
type: UnificationXref
id: H2PZA6
db: uniprot

Anopheles gambiae
type: BioSource
xref: ncbitaxon 7165 24

uniprot P29387 195
type: UnificationXref
id: P29387
db: uniprot

uniprot Q6PH57 252
type: UnificationXref
id: Q6PH57
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F1MYW8 135
organism: Bos taurus

Cryptococcus neoformans
type: BioSource
xref: ncbitaxon 214684 240

Sclerotinia sclerotiorum
type: BioSource
xref: ncbitaxon 665079 116

ncbitaxon 9031 63
type: UnificationXref
id: 9031
db: ncbitaxon

ncbitaxon 6945 118
type: UnificationXref
id: 6945
db: ncbitaxon

uniprot F6TFY2 146
type: UnificationXref
id: F6TFY2
db: uniprot

uniprot F7EBE7 164
type: UnificationXref
id: F7EBE7
db: uniprot

Guanine nucleotide-binding protein subunit beta-1
type: ProteinReference
xref: uniprot P17343 191
organism: Caenorhabditis elegans

GO GO:0008021 2
type: UnificationXref
id: GO:0008021
db: GO

DISSOCIATION_LEFT__GTP-_Complex__GDP_G_Protein__brBetasub_3_NE_-RIGHT__GDP-_Complex__Beta3_NE_-_Complex__GTP_G_Protein_-_re19
type: ComplexAssembly
spontaneous: false
conversion direction: LEFT_TO_RIGHT
xref: DISSOCIATION
participant stoichiometry: PARTICIPANT STOICHIOMETRY re19 323
participant stoichiometry: PARTICIPANT STOICHIOMETRY re19 324
participant stoichiometry: PARTICIPANT STOICHIOMETRY re19 321
participant stoichiometry: PARTICIPANT STOICHIOMETRY re19 320
participant stoichiometry: PARTICIPANT STOICHIOMETRY re19 322
left: GTP
left: Complex (GDP/G-Protein/_brBetasub_3/NE)
interaction type: DISSOCIATION
right: Complex (Beta3/NE)
right: Complex (GTP/G-Protein)
right: GDP

Adenylate cyclase type 2
type: ProteinReference
xref: PTHR45627:SF6
xref: uniprot P26769 285
organism: Rattus norvegicus

uniprot Q17QQ3 78
type: UnificationXref
id: Q17QQ3
db: uniprot

Synaptosomal-associated protein 23
type: ProteinReference
xref: PTHR19305:SF4
xref: uniprot O09044 49
organism: Mus musculus

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q3SZ98 236
organism: Bos taurus

Synaptosomal-associated protein 25-A
type: ProteinReference
xref: PTHR19305:SF5
xref: uniprot Q5TZ66 85
organism: Danio rerio

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F7BB02 158
organism: Macaca mulatta

Gnb1l protein
type: ProteinReference
xref: uniprot Q803H5 261
organism: Danio rerio

G protein subunit alpha L
type: ProteinReference
xref: uniprot F6XVE6 151
organism: Xenopus tropicalis

NE
type: SmallMolecule
cellular location: synaptic vesicle
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q9SD96 102
type: UnificationXref
id: Q9SD96
db: uniprot

Synaptosomal-associated protein
type: ProteinReference
xref: PTHR19305:SF14
xref: uniprot A5PEW5 14
organism: Caenorhabditis elegans

Synaptosomal-associated protein
type: ProteinReference
xref: PTHR19305:SF14
xref: uniprot A8X8S6 17
organism: Caenorhabditis briggsae

uniprot F7EPG4 37
type: UnificationXref
id: F7EPG4
db: uniprot

Branchiostoma floridae
type: BioSource
xref: ncbitaxon 7739 120

ncbitaxon 6239 15
type: UnificationXref
id: 6239
db: ncbitaxon

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F6SSS3 145
organism: Monodelphis domestica

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot H2Q1D9 177
organism: Pan troglodytes

Uncharacterized protein
type: ProteinReference
xref: uniprot F6W548 149
organism: Macaca mulatta

Vesicle-associated membrane protein 1
type: ProteinReference
xref: PTHR45701:SF1
xref: uniprot Q63666 88
organism: Rattus norvegicus

uniprot Q6R0H7 253
type: UnificationXref
id: Q6R0H7
db: uniprot

uniprot F1MJV4 280
type: UnificationXref
id: F1MJV4
db: uniprot

ISS
type: EvidenceCodeVocabulary
xref: eco ECO:0000250 6

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
type: ProteinReference
xref: uniprot P52287 207
organism: Rattus norvegicus

uniprot P63044 71
type: UnificationXref
id: P63044
db: uniprot

Vesicle-associated membrane protein 2
type: ProteinReference
xref: uniprot Q7SZZ5 92
organism: Danio rerio

Synaptosomal-associated protein
type: ProteinReference
xref: PTHR19305:SF4
xref: uniprot F6UBJ8 27
organism: Xenopus tropicalis

Synaptobrevin homolog 2
type: ProteinReference
xref: uniprot P33328 59
organism: Saccharomyces cerevisiae

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q3KRE3 235
organism: Rattus norvegicus

TRANSPORT_LEFT__NE-RIGHT__NE-_re2
type: TransportWithBiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: TRANSPORT
participant stoichiometry: PARTICIPANT STOICHIOMETRY re2 316
participant stoichiometry: PARTICIPANT STOICHIOMETRY re2 317
left: NE
interaction type: TRANSPORT
right: NE

uniprot Q6PBR4 250
type: UnificationXref
id: Q6PBR4
db: uniprot

uniprot P60879 64
type: UnificationXref
id: P60879
db: uniprot

G protein subunit beta 5
type: ProteinReference
xref: uniprot E2RHY4 129
organism: Canis lupus familiaris

ncbitaxon 9598 11
type: UnificationXref
id: 9598
db: ncbitaxon

uniprot A5PEW5 14
type: UnificationXref
id: A5PEW5
db: uniprot

uniprot F5HH30 140
type: UnificationXref
id: F5HH30
db: uniprot

uniprot P50150 203
type: UnificationXref
id: P50150
db: uniprot

uniprot P13945 274
type: UnificationXref
id: P13945
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
type: ProteinReference
xref: uniprot O60262 188
organism: Homo sapiens

Syntaxin-3
type: ProteinReference
xref: PTHR19957:SF34
xref: uniprot Q13277 76
organism: Homo sapiens

uniprot F7CB49 159
type: UnificationXref
id: F7CB49
db: uniprot

Monodelphis domestica
type: BioSource
xref: ncbitaxon 13616 26

uniprot Q62442 87
type: UnificationXref
id: Q62442
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot K7AE17 184
organism: Pan troglodytes

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot D3ZLD6 121
organism: Rattus norvegicus

MODULATION
type: Control
xref: MODULATION
controlled: thermogenesis
controller: ATP

uniprot F6ZAV4 282
type: UnificationXref
id: F6ZAV4
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot E1BW98 123
organism: Gallus gallus

STATE_TRANSITION_LEFT__AC-RIGHT__AC-_re17
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY re17 315
participant stoichiometry: PARTICIPANT STOICHIOMETRY re17 314
left: AC
interaction type: STATE_TRANSITION
right: AC

Synaptosomal-associated protein
type: ProteinReference
xref: PTHR19305:SF5
xref: uniprot F6VUT7 31
organism: Ornithorhynchus anatinus

Synaptosomal-associated protein 23
type: ProteinReference
xref: PTHR19305:SF4
xref: uniprot O00161 46
organism: Homo sapiens

GO GO:0005829 3
type: UnificationXref
id: GO:0005829
db: GO

G Protein s4 sa4 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: G-Protein
stoichiometric coefficient: 1.0

uniprot O70404 53
type: UnificationXref
id: O70404
db: uniprot

PTHR19305:SF5
type: RelationshipXref
id: PTHR19305:SF5
db: PANTHER Family
relationship type: By Homology

Schizosaccharomyces pombe
type: BioSource
xref: ncbitaxon 284812 95

PTHR19305:SF9
type: RelationshipXref
id: PTHR19305:SF9
db: PANTHER Family
relationship type: By Homology

Beta-3 adrenergic receptor
type: ProteinReference
xref: PTHR24248:SF3
xref: uniprot Q28524 277
organism: Macaca mulatta

ncbitaxon 7165 24
type: UnificationXref
id: 7165
db: ncbitaxon

uniprot A5PKD6 114
type: UnificationXref
id: A5PKD6
db: uniprot

uniprot H2Q1D9 177
type: UnificationXref
id: H2Q1D9
db: uniprot

uniprot F1RE11 138
type: UnificationXref
id: F1RE11
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F7G3J2 170
organism: Monodelphis domestica

uniprot P51829 287
type: UnificationXref
id: P51829
db: uniprot

uniprot O09044 49
type: UnificationXref
id: O09044
db: uniprot

Adenylate cyclase
type: ProteinReference
xref: uniprot A0A1D5RHE7 278
xref: PTHR45627:SF6
organism: Macaca mulatta

Beta-3 adrenergic receptor
type: ProteinReference
xref: PTHR24248:SF3
xref: uniprot P26255 276
organism: Rattus norvegicus

uniprot F6Y3N2 153
type: UnificationXref
id: F6Y3N2
db: uniprot

Vesicle associated membrane protein 1
type: ProteinReference
xref: PTHR45701:SF1
xref: uniprot F1PRG8 22
organism: Canis lupus familiaris

uniprot Q7Q6D2 258
type: UnificationXref
id: Q7Q6D2
db: uniprot

uniprot F7DL70 283
type: UnificationXref
id: F7DL70
db: uniprot

ATP
type: SmallMolecule
cellular location: cytosol
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q9S7P9 101
type: UnificationXref
id: Q9S7P9
db: uniprot

uniprot F7CTP1 161
type: UnificationXref
id: F7CTP1
db: uniprot

PTHR19305:SF4
type: RelationshipXref
id: PTHR19305:SF4
db: PANTHER Family
relationship type: By Homology

DISSOCIATION
type: InteractionVocabulary

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q0VFC4 229
organism: Xenopus tropicalis

uniprot P63214 222
type: UnificationXref
id: P63214
db: uniprot

uniprot Q9N0Y0 100
type: UnificationXref
id: Q9N0Y0
db: uniprot

Synaptosomal-associated protein 29
type: ProteinReference
xref: uniprot Q9ERB0 97
xref: PTHR19305:SF9
organism: Mus musculus

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q6DF43 246
organism: Xenopus tropicalis

ncbitaxon 9913 13
type: UnificationXref
id: 9913
db: ncbitaxon

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q6TH03 254
organism: Danio rerio

uniprot Q20636 232
type: UnificationXref
id: Q20636
db: uniprot

uniprot Q8CGK7 263
type: UnificationXref
id: Q8CGK7
db: uniprot

uniprot Q13277 76
type: UnificationXref
id: Q13277
db: uniprot

Guanine nucleotide-binding protein subunit beta-2
type: ProteinReference
xref: uniprot Q20636 232
organism: Caenorhabditis elegans

Guanine nucleotide-binding protein subunit beta-4
type: ProteinReference
xref: uniprot Q9HAV0 267
organism: Homo sapiens

uniprot F1PRG8 22
type: UnificationXref
id: F1PRG8
db: uniprot

uniprot Q61016 244
type: UnificationXref
id: Q61016
db: uniprot

GNB4 protein
type: ProteinReference
xref: uniprot A5PKD6 114
organism: Bos taurus

uniprot Q7ZUC1 93
type: UnificationXref
id: Q7ZUC1
db: uniprot

Homo sapiens
type: BioSource
xref: ncbitaxon 9606 47

Guanine nucleotide-binding protein subunit beta
type: ProteinReference
xref: uniprot Q10282 230
organism: Schizosaccharomyces pombe

Guanine nucleotide-binding protein G(olf) subunit alpha
type: ProteinReference
xref: uniprot P38405 200
organism: Homo sapiens

PANTHER Pathway P04379 1
type: UnificationXref
id: P04379
db: PANTHER Pathway

uniprot P63078 219
type: UnificationXref
id: P63078
db: uniprot

uniprot F6ZIZ9 156
type: UnificationXref
id: F6ZIZ9
db: uniprot

uniprot F7E427 163
type: UnificationXref
id: F7E427
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot E2RJB3 130
organism: Canis lupus familiaris

Arabidopsis thaliana
type: BioSource
xref: ncbitaxon 3702 99

Synaptosomal-associated protein
type: ProteinReference
xref: PTHR19305:SF5
xref: uniprot Q28HP6 79
organism: Xenopus tropicalis

uniprot A0A1D5QDW1 4
type: UnificationXref
id: A0A1D5QDW1
db: uniprot

Guanine nucleotide-binding protein subunit beta
type: ProteinReference
xref: uniprot P18851 192
organism: Saccharomyces cerevisiae

Guanine nucleotide-binding protein subunit beta-5b
type: ProteinReference
xref: uniprot Q6PBY0 251
organism: Danio rerio

uniprot Q7SZZ5 92
type: UnificationXref
id: Q7SZZ5
db: uniprot

uniprot F7EJA3 165
type: UnificationXref
id: F7EJA3
db: uniprot

Gbeta5
type: ProteinReference
xref: uniprot Q9W3J1 270
organism: Drosophila melanogaster

PTHR45701:SF6
type: RelationshipXref
id: PTHR45701:SF6
db: PANTHER Family
relationship type: By Homology

PTHR45701:SF7
type: RelationshipXref
id: PTHR45701:SF7
db: PANTHER Family
relationship type: By Homology

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F1PJE5 137
organism: Canis lupus familiaris

G protein subunit gamma 5
type: ProteinReference
xref: uniprot H2PZA6 176
organism: Pan troglodytes

PTHR45701:SF5
type: RelationshipXref
id: PTHR45701:SF5
db: PANTHER Family
relationship type: By Homology

uniprot P62871 211
type: UnificationXref
id: P62871
db: uniprot

Strongylocentrotus purpuratus
type: BioSource
xref: ncbitaxon 7668 52

PTHR45701:SF3
type: RelationshipXref
id: PTHR45701:SF3
db: PANTHER Family
relationship type: By Homology

PTHR45701:SF1
type: RelationshipXref
id: PTHR45701:SF1
db: PANTHER Family
relationship type: By Homology

uniprot P43425 201
type: UnificationXref
id: P43425
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
type: ProteinReference
xref: uniprot Q9UK08 269
organism: Homo sapiens

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot E1C795 124
organism: Gallus gallus

Beta3
type: Protein
entity reference: Beta3
feature: COMPLEX PARTICIPANT BINDING FEATURE s8 sa8 311
cellular location: cytosol
comment: SPECIES_TYPE=PROTEIN

cAMP
type: SmallMolecule
cellular location: cytosol
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Danio rerio
type: BioSource
xref: ncbitaxon 7955 86

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot R4GKD1 271
organism: Gallus gallus

uniprot E2R2S3 125
type: UnificationXref
id: E2R2S3
db: uniprot

uniprot P63077 218
type: UnificationXref
id: P63077
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F7ES96 167
organism: Macaca mulatta

Uncharacterized protein
type: ProteinReference
xref: uniprot F1NLV4 136
organism: Gallus gallus

uniprot F5HMS4 23
type: UnificationXref
id: F5HMS4
db: uniprot

G-Protein
type: Protein
entity reference: G-Protein
feature: COMPLEX PARTICIPANT BINDING FEATURE s4 sa4 295
cellular location: cytosol
comment: SPECIES_TYPE=PROTEIN

uniprot Q5ZJ03 242
type: UnificationXref
id: Q5ZJ03
db: uniprot

Synaptobrevin homolog 1
type: ProteinReference
xref: uniprot P31109 57
organism: Saccharomyces cerevisiae

uniprot F6VM87 30
type: UnificationXref
id: F6VM87
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot G3V8K2 175
organism: Rattus norvegicus

ncbitaxon 6669 132
type: UnificationXref
id: 6669
db: ncbitaxon

Syntaxin-3
type: ProteinReference
xref: PTHR19957:SF34
xref: uniprot Q08849 74
organism: Rattus norvegicus

uniprot F6W548 149
type: UnificationXref
id: F6W548
db: uniprot

uniprot A0A3Q1MQZ8 272
type: UnificationXref
id: A0A3Q1MQZ8
db: uniprot

G protein subunit beta 2
type: ProteinReference
xref: uniprot A0A2I3TUD1 108
organism: Pan troglodytes

Synaptosomal-associated protein 25
type: ProteinReference
xref: uniprot Q17QQ3 78
xref: PTHR19305:SF5
organism: Bos taurus

GDP s6 sa6 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: GDP
stoichiometric coefficient: 1.0

uniprot Q0V7N0 75
type: UnificationXref
id: Q0V7N0
db: uniprot

uniprot F7F580 168
type: UnificationXref
id: F7F580
db: uniprot

uniprot Q9UBI6 268
type: UnificationXref
id: Q9UBI6
db: uniprot

uniprot F7A943 36
type: UnificationXref
id: F7A943
db: uniprot

Beta3
type: Protein
entity reference: Beta3
feature: COMPLEX PARTICIPANT BINDING FEATURE s5 sa5 297
cellular location: cytosol
comment: SPECIES_TYPE=PROTEIN

Guanine nucleotide-binding protein G(f) subunit alpha
type: ProteinReference
xref: uniprot Q05337 228
organism: Drosophila melanogaster

uniprot Q5BJ11 238
type: UnificationXref
id: Q5BJ11
db: uniprot

Guanine nucleotide-binding protein beta subunit
type: ProteinReference
xref: uniprot A7EDU2 115
organism: Sclerotinia sclerotiorum

uniprot F6PV18 143
type: UnificationXref
id: F6PV18
db: uniprot

Vesicle-associated membrane protein 2
type: ProteinReference
xref: uniprot Q9N0Y0 100
xref: PTHR45701:SF5
organism: Macaca mulatta

Guanine nucleotide-binding protein (G protein), alpha-activating activity polypeptide, olfactory type
type: ProteinReference
xref: uniprot F1RE11 138
organism: Danio rerio

Vesicle-associated membrane protein 8
type: ProteinReference
xref: uniprot Q3T0Y8 81
xref: PTHR45701:SF7
organism: Bos taurus

Synaptosomal-associated protein 25
type: ProteinReference
xref: PTHR19305:SF14
xref: uniprot P36975 60
organism: Drosophila melanogaster

uniprot P63027 70
type: UnificationXref
id: P63027
db: uniprot

SNAP29 isoform 1
type: ProteinReference
xref: PTHR19305:SF9
xref: uniprot H2QLA1 42
organism: Pan troglodytes

SNARE COMPLEX
type: ProteinReference
xref: P04447
standard name: SNARE Complex
comment: ENTITY_REFERENCE_ID_DESC=Beta3 adrenergic receptor signaling pathway.PROTEIN.GENERIC.SNARE COMPLEX
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: SNARE COMPLEX Synonym: Synonym not specified Accession: P04447
member entity reference: VAMP2 isoform 3
member entity reference: Neuronal synaptobrevin, isoform J
member entity reference: Syntaxin 3
member entity reference: Synaptobrevin homolog 1
member entity reference: Uncharacterized protein
member entity reference: Synaptosomal-associated protein 25-B
member entity reference: Putative synaptobrevin homologue SNC1/2 (Eurofung)
member entity reference: Synaptosomal-associated protein 25
member entity reference: Syntaxin-3
member entity reference: Synaptobrevin-1
member entity reference: Synaptosomal-associated protein 29
member entity reference: Synaptosomal-associated protein
member entity reference: LD03592p
member entity reference: SNAP29 isoform 1
member entity reference: Vesicle-associated membrane protein 2
member entity reference: t-SNARE protein aex-4
member entity reference: SNAP25 homologous protein SNAP33
member entity reference: Vesicle-associated membrane protein 1
member entity reference: Vesicle-associated membrane protein 8 (Endobrevin)
member entity reference: Synaptobrevin
member entity reference: Vesicle-associated membrane protein 3
member entity reference: Putative SNAP25 homologous protein SNAP30
member entity reference: Vesicle-associated membrane protein 8
member entity reference: Vesicle associated membrane protein 8
member entity reference: Synaptosomal-associated protein 23
member entity reference: Syntaxin 3A
member entity reference: Synaptosomal-associated protein 25-A
member entity reference: Soluble NSF attachment protein 29
member entity reference: Vesicle associated membrane protein 1

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F6YZA3 154
organism: Monodelphis domestica

uniprot A1L271 111
type: UnificationXref
id: A1L271
db: uniprot

PTHR45627:SF9
type: RelationshipXref
id: PTHR45627:SF9
db: PANTHER Family
relationship type: By Homology

Vesicle-associated membrane protein 3
type: ProteinReference
xref: PTHR45701:SF6
xref: uniprot Q15836 77
organism: Homo sapiens

uniprot P62872 212
type: UnificationXref
id: P62872
db: uniprot

uniprot P52287 207
type: UnificationXref
id: P52287
db: uniprot

PTHR45627:SF6
type: RelationshipXref
id: PTHR45627:SF6
db: PANTHER Family
relationship type: By Homology

uniprot K7AE17 184
type: UnificationXref
id: K7AE17
db: uniprot

uniprot F6XWE8 152
type: UnificationXref
id: F6XWE8
db: uniprot

NE
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Dictyostelium discoideum
type: BioSource
xref: ncbitaxon 44689 199

ncbitaxon 9615 20
type: UnificationXref
id: 9615
db: ncbitaxon

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F2Z3T8 139
organism: Rattus norvegicus

HETERODIMER_ASSOCIATION
type: InteractionVocabulary

uniprot F6VPY1 148
type: UnificationXref
id: F6VPY1
db: uniprot

uniprot Q6TH03 254
type: UnificationXref
id: Q6TH03
db: uniprot

uniprot F7GI54 172
type: UnificationXref
id: F7GI54
db: uniprot

uniprot H2R1M3 273
type: UnificationXref
id: H2R1M3
db: uniprot

uniprot P62879 215
type: UnificationXref
id: P62879
db: uniprot

Synaptosomal-associated protein 25-B
type: ProteinReference
xref: uniprot Q6PC54 90
xref: PTHR19305:SF5
organism: Danio rerio

uniprot P31109 57
type: UnificationXref
id: P31109
db: uniprot

IC
type: EvidenceCodeVocabulary
xref: eco ECO:0000305 16

Synaptosomal-associated protein
type: ProteinReference
xref: PTHR19305:SF14
xref: uniprot O44419 51
organism: Strongylocentrotus purpuratus

uniprot Q10282 230
type: UnificationXref
id: Q10282
db: uniprot

TRIGGER
type: Control
xref: TRIGGER
controlled: TRANSPORT_LEFT__NE-RIGHT__NE-_re2
control type: ACTIVATION
controller: SNARE COMPLEX

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot K7E376 185
organism: Monodelphis domestica

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
type: ProteinReference
xref: uniprot Q80SZ7 262
organism: Mus musculus

Guanine nucleotide binding protein (G protein), beta polypeptide 3, like
type: ProteinReference
xref: uniprot Q6DH55 248
organism: Danio rerio

uniprot F7BB02 158
type: UnificationXref
id: F7BB02
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F6TFY2 146
organism: Macaca mulatta

PARTICIPANT STOICHIOMETRY re17 314
type: Stoichiometry
physical entity: AC
stoichiometric coefficient: 1.0

uniprot Q7Q6D3 259
type: UnificationXref
id: Q7Q6D3
db: uniprot

uniprot Q63666 88
type: UnificationXref
id: Q63666
db: uniprot

uniprot A0A1D5QYR9 9
type: UnificationXref
id: A0A1D5QYR9
db: uniprot

PARTICIPANT STOICHIOMETRY re17 315
type: Stoichiometry
physical entity: AC
stoichiometric coefficient: 1.0

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q90Z40 264
organism: Danio rerio

uniprot P62874 214
type: UnificationXref
id: P62874
db: uniprot

uniprot Q08849 74
type: UnificationXref
id: Q08849
db: uniprot

uniprot Q9UK08 269
type: UnificationXref
id: Q9UK08
db: uniprot

Vesicle-associated membrane protein 1
type: ProteinReference
xref: PTHR45701:SF1
xref: uniprot Q62442 87
organism: Mus musculus

Rattus norvegicus
type: BioSource
xref: ncbitaxon 10116 68

NE
type: SmallMolecule
feature: COMPLEX PARTICIPANT BINDING FEATURE s9 sa9 313
cellular location: cytosol
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot P18851 192
type: UnificationXref
id: P18851
db: uniprot

Guanine nucleotide-binding protein subunit beta-4
type: ProteinReference
xref: uniprot F6ZIZ9 156
organism: Macaca mulatta

Daphnia pulex
type: BioSource
xref: ncbitaxon 6669 132

uniprot F6VUT7 31
type: UnificationXref
id: F6VUT7
db: uniprot

uniprot Q7Q6D4 260
type: UnificationXref
id: Q7Q6D4
db: uniprot

NE
type: SmallMolecule
feature: COMPLEX PARTICIPANT BINDING FEATURE s11 sa11 305
cellular location: cytosol
comment: SPECIES_TYPE=SIMPLE_MOLECULE

lipolysis
type: Pathway

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
type: ProteinReference
xref: uniprot P63078 219
organism: Mus musculus

t-SNARE protein aex-4
type: ProteinReference
xref: uniprot G5EEN8 39
organism: Caenorhabditis elegans

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
type: ProteinReference
xref: uniprot P63077 218
organism: Rattus norvegicus

ncbitaxon 7668 52
type: UnificationXref
id: 7668
db: ncbitaxon

uniprot P63212 220
type: UnificationXref
id: P63212
db: uniprot

GDP
type: SmallMolecule
cellular location: cytosol
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot G2HIJ9 38
type: UnificationXref
id: G2HIJ9
db: uniprot

G Protein s2 sa2 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: G-Protein
stoichiometric coefficient: 1.0

uniprot Q80SZ7 262
type: UnificationXref
id: Q80SZ7
db: uniprot

LD03592p
type: ProteinReference
xref: uniprot Q9W1I8 104
xref: PTHR19305:SF9
organism: Drosophila melanogaster

G-Protein
type: Protein
entity reference: G-Protein
feature: COMPLEX PARTICIPANT BINDING FEATURE s7 sa7 309
cellular location: cytosol
comment: SPECIES_TYPE=PROTEIN

Vesicle-associated membrane protein 1
type: ProteinReference
xref: PTHR45701:SF1
xref: uniprot P23763 56
organism: Homo sapiens

G protein subunit beta 3
type: ProteinReference
xref: uniprot H2R3A6 182
organism: Pan troglodytes

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
type: ProteinReference
xref: uniprot P54313 209
organism: Rattus norvegicus

uniprot F1A421 133
type: UnificationXref
id: F1A421
db: uniprot

ncbitaxon 13616 26
type: UnificationXref
id: 13616
db: ncbitaxon

Adenylate cyclase
type: ProteinReference
xref: uniprot F6ZAV4 282
xref: PTHR45627:SF6
organism: Ornithorhynchus anatinus

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
type: ProteinReference
xref: uniprot P54311 208
organism: Rattus norvegicus

uniprot F6V461 147
type: UnificationXref
id: F6V461
db: uniprot

uniprot H2Q3R5 40
type: UnificationXref
id: H2Q3R5
db: uniprot

Putative SNAP25 homologous protein SNAP30
type: ProteinReference
xref: uniprot Q9LMG8 98
organism: Arabidopsis thaliana

uniprot G3V6P8 174
type: UnificationXref
id: G3V6P8
db: uniprot

uniprot Q9W1I8 104
type: UnificationXref
id: Q9W1I8
db: uniprot

uniprot Q7PXP3 256
type: UnificationXref
id: Q7PXP3
db: uniprot

uniprot Q92356 94
type: UnificationXref
id: Q92356
db: uniprot

STATE_TRANSITION
type: InteractionVocabulary

G protein subunit beta 4
type: ProteinReference
xref: uniprot F7E427 163
organism: Ornithorhynchus anatinus

TRANSPORT
type: InteractionVocabulary

uniprot P36408 198
type: UnificationXref
id: P36408
db: uniprot

Vesicle-associated membrane protein 1
type: ProteinReference
xref: PTHR45701:SF1
xref: uniprot Q0V7N0 75
organism: Bos taurus

uniprot H2QNS5 180
type: UnificationXref
id: H2QNS5
db: uniprot

Adenylate cyclase
type: ProteinReference
xref: PTHR45627:SF6
xref: uniprot F6V001 281
organism: Monodelphis domestica

uniprot Q6PHV0 91
type: UnificationXref
id: Q6PHV0
db: uniprot

uniprot A0A2I3SR99 10
type: UnificationXref
id: A0A2I3SR99
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
type: ProteinReference
xref: uniprot Q6PH57 252
organism: Danio rerio

Adenylate cyclase
type: ProteinReference
xref: PTHR45627:SF6
xref: uniprot F1MJV4 280
organism: Bos taurus

uniprot A4IFL6 112
type: UnificationXref
id: A4IFL6
db: uniprot

uniprot P63213 221
type: UnificationXref
id: P63213
db: uniprot

uniprot F1NLV4 136
type: UnificationXref
id: F1NLV4
db: uniprot

GDP
type: SmallMolecule
feature: COMPLEX PARTICIPANT BINDING FEATURE s3 sa3 293
cellular location: cytosol
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot E1BS74 122
type: UnificationXref
id: E1BS74
db: uniprot

uniprot O44419 51
type: UnificationXref
id: O44419
db: uniprot

uniprot H2QLA1 42
type: UnificationXref
id: H2QLA1
db: uniprot

Beta-3 adrenergic receptor
type: ProteinReference
xref: PTHR24248:SF3
xref: uniprot P25962 275
organism: Mus musculus

Dictyostelium purpureum
type: BioSource
xref: ncbitaxon 5786 134

uniprot Q08462 288
type: UnificationXref
id: Q08462
db: uniprot

Adenylate cyclase
type: ProteinReference
xref: uniprot F7DL70 283
xref: PTHR45627:SF9
organism: Macaca mulatta

uniprot Q3KRE3 235
type: UnificationXref
id: Q3KRE3
db: uniprot

PARTICIPANT STOICHIOMETRY re9 319
type: Stoichiometry
physical entity: cAMP
stoichiometric coefficient: 1.0

PTHR19957:SF34
type: RelationshipXref
id: PTHR19957:SF34
db: PANTHER Family
relationship type: By Homology

PARTICIPANT STOICHIOMETRY re9 318
type: Stoichiometry
physical entity: ATP
stoichiometric coefficient: 1.0

uniprot P62881 217
type: UnificationXref
id: P62881
db: uniprot

STATE_TRANSITION_LEFT__ATP-RIGHT__cAMP-_re9
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY re9 318
participant stoichiometry: PARTICIPANT STOICHIOMETRY re9 319
left: ATP
interaction type: STATE_TRANSITION
right: cAMP

uniprot B7Q3T6 117
type: UnificationXref
id: B7Q3T6
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR45701:SF7
xref: uniprot A0A1D5QIS2 8
organism: Macaca mulatta

cytosol
type: CellularLocationVocabulary
xref: GO GO:0005829 3

Beta3
type: ProteinReference
xref: P04449
standard name: Beta3 adrenergic receptor
comment: ENTITY_REFERENCE_NOTES=
comment: ENTITY_REFERENCE_ID_DESC=Beta3 adrenergic receptor signaling pathway.PROTEIN.RECEPTOR.Beta_sub_3
comment: ENTITY_REFERENCE_PROTEIN_TYPE=RECEPTOR
member entity reference: Beta-3 adrenergic receptor
member entity reference: Adrenoceptor beta 3

uniprot Q6PBY0 251
type: UnificationXref
id: Q6PBY0
db: uniprot

uniprot Q80TL1 290
type: UnificationXref
id: Q80TL1
db: uniprot

uniprot P62880 216
type: UnificationXref
id: P62880
db: uniprot

uniprot Q29450 289
type: UnificationXref
id: Q29450
db: uniprot

uniprot Q9BV40 96
type: UnificationXref
id: Q9BV40
db: uniprot

uniprot F1MYW8 135
type: UnificationXref
id: F1MYW8
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F6ZDB2 155
xref: PTHR10218:SF320
organism: Monodelphis domestica

Beta3 s8 sa8 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Beta3
stoichiometric coefficient: 1.0

uniprot Q803H5 261
type: UnificationXref
id: Q803H5
db: uniprot

HETERODIMER_ASSOCIATION
type: RelationshipTypeVocabulary

Beta3 adrenergic receptor signaling pathway
type: Pathway
pathway component: HETERODIMER_ASSOCIATION_LEFT__NE-_Complex__GDP_G_Protein__brBetasub_3_-RIGHT__Complex__GDP_G_Protein__brBetasub_3_NE_-_re18
pathway component: DISSOCIATION_LEFT__GTP-_Complex__GDP_G_Protein__brBetasub_3_NE_-RIGHT__GDP-_Complex__Beta3_NE_-_Complex__GTP_G_Protein_-_re19
pathway component: MODULATION
pathway component: STATE_TRANSITION_LEFT__AC-RIGHT__AC-_re17
pathway component: TRANSPORT_LEFT__NE-RIGHT__NE-_re2
pathway component: STATE_TRANSITION_LEFT__ATP-RIGHT__cAMP-_re9
xref: PANTHER Pathway P04379 1
comment: MODEL_NOTES=Panther Pathway: P04379 "http://www.adrenoceptor.com/b3adrenoceptors.htm"

Synaptosomal-associated protein
type: ProteinReference
xref: PTHR19305:SF4
xref: uniprot H2Q995 41
organism: Pan troglodytes

Syntaxin 3A
type: ProteinReference
xref: PTHR19957:SF34
xref: uniprot Q6PHV0 91
organism: Danio rerio

uniprot P20354 193
type: UnificationXref
id: P20354
db: uniprot

uniprot P26308 194
type: UnificationXref
id: P26308
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F7ERP8 166
organism: Ornithorhynchus anatinus

uniprot O02495 48
type: UnificationXref
id: O02495
db: uniprot

Guanine nucleotide-binding protein (G protein), beta 5
type: ProteinReference
xref: uniprot F7EBE7 164
organism: Xenopus tropicalis

Syntaxin 3
type: ProteinReference
xref: PTHR19957:SF34
xref: uniprot F7EPG4 37
organism: Ornithorhynchus anatinus

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F6VPY1 148
organism: Ornithorhynchus anatinus

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
type: ProteinReference
xref: uniprot P59768 210
organism: Homo sapiens

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
type: ProteinReference
xref: uniprot P16520 190
organism: Homo sapiens

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F6V461 147
organism: Ornithorhynchus anatinus

Guanine nucleotide-binding protein subunit beta
type: ProteinReference
xref: uniprot P36408 198
organism: Dictyostelium discoideum

uniprot P59768 210
type: UnificationXref
id: P59768
db: uniprot

Emericella nidulans
type: BioSource
xref: ncbitaxon 227321 83

Uncharacterized protein
type: ProteinReference
xref: uniprot F7EJA3 165
xref: PTHR10218:SF320
organism: Ornithorhynchus anatinus

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q6PBR4 250
organism: Danio rerio

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q6DGZ5 247
organism: Danio rerio

uniprot P26769 285
type: UnificationXref
id: P26769
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot J9P702 183
organism: Canis lupus familiaris