PTHR11937:SF411
type: RelationshipXref
id: PTHR11937:SF411
db: PANTHER Family
relationship type: By Homology

Actin, aortic smooth muscle
type: ProteinReference
xref: PTHR11937:SF201
xref: uniprot F1P476 240
organism: Gallus gallus

PTHR11937:SF414
type: RelationshipXref
id: PTHR11937:SF414
db: PANTHER Family
relationship type: By Homology

Y142 betacatenin s3 a16 rs2
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y142
feature location: Y142 betacatenin s3 a16 rs2 Y142
comment: MODIFICATION_RESIDUE_NAME=Y142
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=2.893781136851091

uniprot Q91XZ4 690
type: UnificationXref
id: Q91XZ4
db: uniprot

PTHR11937:SF410
type: RelationshipXref
id: PTHR11937:SF410
db: PANTHER Family
relationship type: By Homology

uniprot P16591 160
type: UnificationXref
id: P16591
db: uniprot

Complex (alphacatenin/F-actin)
type: Complex
component stoichiometry: alphacatenin s2 sa6 STOICHIOMETRY ID COMPLEX
component stoichiometry: F actin s4 sa7 STOICHIOMETRY ID COMPLEX
component: alphacatenin
component: F-actin
feature: COMPLEX BINDING FEATURE s54 a83 1102
feature: COMPLEX BINDING FEATURE s54 a83 1100
cellular location: cytoplasm

Uncharacterized protein
type: ProteinReference
xref: PTHR24028:SF71
xref: uniprot H2QRN3 571
organism: Pan troglodytes

Protocadherin 18
type: ProteinReference
xref: uniprot F1PD90 488
xref: PTHR24028:SF9
organism: Canis lupus familiaris

Protocadherin beta-5
type: ProteinReference
xref: uniprot H2QRN2 570
xref: PTHR24028:SF90
organism: Pan troglodytes

GSK3beta
type: ProteinReference
xref: P00477
standard name: Glycogen synthase kinase 3-beta
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Glycogen synthase kinase 3-beta Synonym: GSK3B Accession: P00477
comment: ENTITY_REFERENCE_ID_DESC=Cadherin signaling pathway.PROTEIN.GENERIC.GSK3_beta_
member entity reference: Glycogen synthase kinase-3 beta
member entity reference: Glycogen synthase kinase-3 beta isoform 1
member entity reference: Glycogen synthase kinase 3 beta
member entity reference: Glycogen synthase kinase 3
member entity reference: Uncharacterized protein
member entity reference: Si:dkeyp-80c12.7

uniprot Q9Y5I3 781
type: UnificationXref
id: Q9Y5I3
db: uniprot

Tyrosine-protein kinase
type: ProteinReference
xref: PTHR24418:SF90
xref: uniprot A0A2I3TMT4 1062
organism: Pan troglodytes

Protocadherin beta-16
type: ProteinReference
xref: PTHR24028:SF71
xref: uniprot Q9NRJ7 720
organism: Homo sapiens

uniprot Q7ZU33 63
type: UnificationXref
id: Q7ZU33
db: uniprot

nucleus
type: CellularLocationVocabulary
xref: GO GO:0005634 2

uniprot A0A0R4IFF8 397
type: UnificationXref
id: A0A0R4IFF8
db: uniprot

Dachsous cadherin-related 1
type: ProteinReference
xref: PTHR24027:SF423
xref: uniprot A0A2I3TID8 418
organism: Pan troglodytes

Protocadherin 10
type: ProteinReference
xref: uniprot A0A3Q1LYG2 430
xref: PTHR24028:SF0
organism: Bos taurus

uniprot P12830 590
type: UnificationXref
id: P12830
db: uniprot

Frizzled class receptor 4
type: ProteinReference
xref: PTHR11309:SF23
xref: uniprot F6V5F4 1001
organism: Xenopus tropicalis

PARTICIPANT STOICHIOMETRY r42 1180
type: Stoichiometry
physical entity: Cadherin
stoichiometric coefficient: 1.0

ncbitaxon 13616 28
type: UnificationXref
id: 13616
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r42 1181
type: Stoichiometry
physical entity: Complex (betacatenin/alphacatenin/ F-actin)
stoichiometric coefficient: 1.0

PTHR11937:SF409
type: RelationshipXref
id: PTHR11937:SF409
db: PANTHER Family
relationship type: By Homology

uniprot E7FC99 70
type: UnificationXref
id: E7FC99
db: uniprot

PARTICIPANT STOICHIOMETRY r42 1182
type: Stoichiometry
physical entity: Complex (Cadherin/betacatenin/ alphacatenin/F-actin)
stoichiometric coefficient: 1.0

PTHR11937:SF408
type: RelationshipXref
id: PTHR11937:SF408
db: PANTHER Family
relationship type: By Homology

T112 betacatenin s30 sa17 rs3
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY T112
feature location: T112 betacatenin s30 sa17 rs3 T112
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=T112
comment: MODIFICATION_RESIDUE_ANGLE=-0.0

Protein Wnt
type: ProteinReference
xref: uniprot Q28IC7 939
xref: PTHR12027:SF92
organism: Xenopus tropicalis

uniprot E9FZ00 234
type: UnificationXref
id: E9FZ00
db: uniprot

PARTICIPANT STOICHIOMETRY r52 1145
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r52 1144
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

T112 betacatenin s112 a160 rs3
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY T112
feature location: T112 betacatenin s112 a160 rs3 T112
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=T112
comment: MODIFICATION_RESIDUE_ANGLE=-0.0

betacatenin
type: Protein
entity reference: betacatenin
feature: S betacatenin s3 a16 rs4
feature: Y142 betacatenin s3 a16 rs2
feature: Y654 betacatenin s3 a16 rs1
feature: betacatenin s3 a16 rs5
feature: T112 betacatenin s3 a16 rs3
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

uniprot Q8ILW9 383
type: UnificationXref
id: Q8ILW9
db: uniprot

Frizzled-2
type: ProteinReference
xref: uniprot Q08464 1027
xref: PTHR11309:SF34
organism: Rattus norvegicus

Frizzled-1
type: ProteinReference
xref: PTHR11309:SF81
xref: uniprot Q08463 1026
organism: Rattus norvegicus

uniprot Q91XZ8 694
type: UnificationXref
id: Q91XZ8
db: uniprot

Protein Wnt
type: ProteinReference
xref: uniprot F7EV26 871
xref: PTHR12027:SF7
organism: Macaca mulatta

CDH12 isoform 1
type: ProteinReference
xref: PTHR24027:SF96
xref: uniprot A0A2J8KU53 422
organism: Pan troglodytes

Mus musculus
type: BioSource
xref: ncbitaxon 10090 40

F-actin
type: ProteinReference
xref: P00470
standard name: Filamentous F-actin
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Filamentous F-actin Synonym: Synonym not specified Accession: P00470
comment: ENTITY_REFERENCE_ID_DESC=Cadherin signaling pathway.PROTEIN.GENERIC.F_minus_actin
member entity reference: Actin, alpha cardiac muscle 1
member entity reference: Alpha-cardiac actin
member entity reference: Actin-related protein 2
member entity reference: Uncharacterized protein
member entity reference: actin, muscle-like
member entity reference: Actin 5
member entity reference: Actin-42A
member entity reference: Actin, putative (Fragment)
member entity reference: Protein CBG02162
member entity reference: Actin
member entity reference: Predicted protein
member entity reference: Putative actin-22
member entity reference: ACTA1 isoform 1
member entity reference: Actin-2
member entity reference: Actin-3
member entity reference: Non-muscle actin 6.2
member entity reference: AGAP001676-PA
member entity reference: Actin, alpha 1, skeletal muscle
member entity reference: Actin, larval muscle
member entity reference: Actin, cytoplasmic 1
member entity reference: Actin, aortic smooth muscle
member entity reference: Actin 7
member entity reference: Actin-10
member entity reference: Actin, alpha skeletal muscle
member entity reference: Actin alpha 1, skeletal muscle a
member entity reference: Putative actin-23
member entity reference: Actin-related protein 2-B
member entity reference: Actin, gamma
member entity reference: Putative actin
member entity reference: Actin-4
member entity reference: Actin-7
member entity reference: Actin, gamma-enteric smooth muscle
member entity reference: Actin-5C
member entity reference: Actin, beta like 2
member entity reference: Actin, cytoskeletal 3B
member entity reference: Actin, indirect flight muscle
member entity reference: Actin-like protein 53D
member entity reference: Actin, muscle
member entity reference: Actin alpha 2, smooth muscle
member entity reference: Protein CBG02161

uniprot P93738 341
type: UnificationXref
id: P93738
db: uniprot

ncbitaxon 9615 21
type: UnificationXref
id: 9615
db: ncbitaxon

uniprot P97326 617
type: UnificationXref
id: P97326
db: uniprot

uniprot Q9ULV1 1055
type: UnificationXref
id: Q9ULV1
db: uniprot

uniprot Q7Q1M9 659
type: UnificationXref
id: Q7Q1M9
db: uniprot

uniprot P60706 309
type: UnificationXref
id: P60706
db: uniprot

DISSOCIATION_LEFT__Complex__Cadherin_betacatenin__alphacatenin_F_actin_-RIGHT__Complex__Cadherin_betacatenin_-_Complex__alphacatenin_F_actin_-_r21
type: ComplexAssembly
spontaneous: false
conversion direction: LEFT_TO_RIGHT
xref: DISSOCIATION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r21 1148
participant stoichiometry: PARTICIPANT STOICHIOMETRY r21 1146
participant stoichiometry: PARTICIPANT STOICHIOMETRY r21 1147
left: Complex (Cadherin/betacatenin/ alphacatenin/F-actin)
interaction type: DISSOCIATION
right: Complex (alphacatenin/F-actin)
right: Complex (Cadherin/betacatenin)

By Homology
type: RelationshipTypeVocabulary

Frizzled-3
type: ProteinReference
xref: uniprot O77438 1024
xref: PTHR11309:SF99
organism: Drosophila melanogaster

uniprot E3K4I1 230
type: UnificationXref
id: E3K4I1
db: uniprot

Actin related protein
type: ProteinReference
xref: uniprot A8BV70 185
xref: PTHR11937:SF387
organism: Giardia intestinalis

Y142 betacatenin s112 a160 rs2
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y142
feature location: Y142 betacatenin s112 a160 rs2 Y142
modification type: phosphorylated residue
comment: MODIFICATION_RESIDUE_NAME=Y142
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=2.893781136851091

Casein kinase II subunit alpha
type: ProteinReference
xref: uniprot P68399 57
xref: PTHR24054:SF16
organism: Bos taurus

uniprot D4A3K6 836
type: UnificationXref
id: D4A3K6
db: uniprot

Actin-related protein 2
type: ProteinReference
xref: PTHR11937:SF37
xref: uniprot F6ZPQ4 256
organism: Monodelphis domestica

uniprot Q9Y5G2 762
type: UnificationXref
id: Q9Y5G2
db: uniprot

uniprot P63268 324
type: UnificationXref
id: P63268
db: uniprot

Cadherin related 23
type: ProteinReference
xref: PTHR24027:SF425
xref: uniprot F1P8X5 487
organism: Canis lupus familiaris

Cytoplasmatic actin
type: ProteinReference
xref: PTHR11937:SF387
xref: uniprot E9FXV8 233
organism: Daphnia pulex

uniprot Q96QU1 707
type: UnificationXref
id: Q96QU1
db: uniprot

Actin-related protein 2
type: ProteinReference
xref: PTHR11937:SF37
xref: uniprot A7MB62 179
organism: Bos taurus

Uncharacterized protein
type: ProteinReference
xref: PTHR24028:SF258
xref: uniprot F6S1W0 496
organism: Macaca mulatta

Predicted protein
type: ProteinReference
xref: uniprot A7S0V7 181
xref: PTHR11937:SF387
organism: Nematostella vectensis

uniprot Q7QAQ8 662
type: UnificationXref
id: Q7QAQ8
db: uniprot

uniprot F7A7I3 258
type: UnificationXref
id: F7A7I3
db: uniprot

Neurospora crassa
type: BioSource
xref: ncbitaxon 367110 337

Uncharacterized protein
type: ProteinReference
xref: PTHR24027:SF272
xref: uniprot F6UDC8 499
organism: Macaca mulatta

Protocadherin 8
type: ProteinReference
xref: PTHR24028:SF46
xref: uniprot H2Q7M1 561
organism: Pan troglodytes

Tyrosine-protein kinase Yes
type: ProteinReference
xref: PTHR24418:SF90
xref: uniprot Q04736 1075
organism: Mus musculus

Protocadherin-11 Y-linked
type: ProteinReference
xref: PTHR24028:SF295
xref: uniprot Q9BZA8 711
organism: Homo sapiens

uniprot Q91XZ2 689
type: UnificationXref
id: Q91XZ2
db: uniprot

Cadherin-8
type: ProteinReference
xref: uniprot P97291 616
xref: PTHR24027:SF273
organism: Mus musculus

uniprot B3RKR4 205
type: UnificationXref
id: B3RKR4
db: uniprot

Protocadherin-11 X-linked
type: ProteinReference
xref: PTHR24028:SF254
xref: uniprot Q9BZA7 710
organism: Homo sapiens

uniprot E9Q9Q6 466
type: UnificationXref
id: E9Q9Q6
db: uniprot

uniprot Q801F7 951
type: UnificationXref
id: Q801F7
db: uniprot

uniprot Q0IPW3 342
type: UnificationXref
id: Q0IPW3
db: uniprot

uniprot E1B969 445
type: UnificationXref
id: E1B969
db: uniprot

T112 betacatenin s93 a132 rs3
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY T112
feature location: T112 betacatenin s93 a132 rs3 T112
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=T112
comment: MODIFICATION_RESIDUE_ANGLE=-0.0

Uncharacterized protein
type: ProteinReference
xref: uniprot F7HPU3 552
xref: PTHR24028:SF9
organism: Macaca mulatta

Protein Wnt
type: ProteinReference
xref: uniprot A0A1D5R803 810
xref: PTHR12027:SF73
organism: Macaca mulatta

uniprot Q61526 141
type: UnificationXref
id: Q61526
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F6UY89 502
xref: PTHR24028:SF97
organism: Macaca mulatta

Protein Wnt-8a
type: ProteinReference
xref: PTHR12027:SF92
xref: uniprot Q64527 948
organism: Mus musculus

uniprot O95206 586
type: UnificationXref
id: O95206
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F7E6I8 533
xref: PTHR24027:SF81
organism: Monodelphis domestica

ACTIVE 162
type: EntityFeature
comment: Active state

uniprot Q9JIP6 1049
type: UnificationXref
id: Q9JIP6
db: uniprot

Transcription factor 7-like 2
type: ProteinReference
xref: uniprot Q924A0 112
xref: PTHR10373:SF32
organism: Mus musculus

uniprot Q9Y5F2 756
type: UnificationXref
id: Q9Y5F2
db: uniprot

Catenin delta-1
type: ProteinReference
xref: uniprot O60716 802
organism: Homo sapiens

uniprot Q01279 139
type: UnificationXref
id: Q01279
db: uniprot

Cadherin-1
type: ProteinReference
xref: PTHR24027:SF319
xref: uniprot P09803 587
organism: Mus musculus

Frizzled class receptor 2
type: ProteinReference
xref: uniprot F6SH04 999
xref: PTHR11309:SF34
organism: Xenopus tropicalis

Cadherin-related family member 1
type: ProteinReference
xref: PTHR24028:SF263
xref: uniprot Q96JP9 705
organism: Homo sapiens

Epidermal growth factor receptor
type: ProteinReference
xref: PTHR24416:SF91
xref: uniprot P55245 137
organism: Macaca mulatta

Protocadherin b
type: ProteinReference
xref: uniprot E7FAU6 462
organism: Danio rerio

PTHR11937:SF453
type: RelationshipXref
id: PTHR11937:SF453
db: PANTHER Family
relationship type: By Homology

Protocadherin-18
type: ProteinReference
xref: uniprot A7MB46 436
xref: PTHR24028:SF9
organism: Bos taurus

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF92
xref: uniprot D4A9D7 838
organism: Rattus norvegicus

Actin
type: ProteinReference
xref: uniprot Q6XNL8 371
xref: PTHR11937:SF389
organism: Danio rerio

Uncharacterized protein
type: ProteinReference
xref: PTHR24026:SF49
xref: uniprot F1MC84 477
organism: Bos taurus

Frizzled class receptor 2
type: ProteinReference
xref: PTHR11309:SF34
xref: uniprot G3N2W8 1009
organism: Bos taurus

uniprot Q5DRD3 636
type: UnificationXref
id: Q5DRD3
db: uniprot

uniprot A0A0G2K5L1 395
type: UnificationXref
id: A0A0G2K5L1
db: uniprot

Protocadherin beta 3
type: ProteinReference
xref: PTHR24028:SF118
xref: uniprot G3V8P1 556
organism: Rattus norvegicus

uniprot F6PJR9 854
type: UnificationXref
id: F6PJR9
db: uniprot

Cadherin EGF LAG seven-pass G-type receptor 2
type: ProteinReference
xref: uniprot G3V8P3 557
xref: PTHR24026:SF32
organism: Rattus norvegicus

Frizzled class receptor 7a
type: ProteinReference
xref: uniprot Q6NV44 1038
xref: PTHR11309:SF31
organism: Danio rerio

Y654 betacatenin s94 a133 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y654
feature location: Y654 betacatenin s94 a133 rs1 Y654
comment: MODIFICATION_RESIDUE_ANGLE=3.3479165476195107
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=Y654

Protocadherin-16
type: ProteinReference
xref: PTHR24027:SF423
xref: uniprot Q96JQ0 706
organism: Homo sapiens

AGAP006732-PA
type: ProteinReference
xref: uniprot Q7PT75 656
xref: PTHR24026:SF108
organism: Anopheles gambiae

uniprot F1QUN8 241
type: UnificationXref
id: F1QUN8
db: uniprot

Casein kinase II subunit alpha
type: ProteinReference
xref: PTHR24054:SF34
xref: uniprot H9ENR6 36
organism: Macaca mulatta

Uncharacterized protein
type: ProteinReference
xref: uniprot F7GJC2 542
xref: PTHR24027:SF419
organism: Macaca mulatta

uniprot Q9Y5H9 777
type: UnificationXref
id: Q9Y5H9
db: uniprot

PTHR11937:SF446
type: RelationshipXref
id: PTHR11937:SF446
db: PANTHER Family
relationship type: By Homology

PTHR11937:SF445
type: RelationshipXref
id: PTHR11937:SF445
db: PANTHER Family
relationship type: By Homology

T112 betacatenin s94 a133 rs3
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY T112
feature location: T112 betacatenin s94 a133 rs3 T112
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=T112
comment: MODIFICATION_RESIDUE_ANGLE=-0.0

uniprot Q6PFX6 649
type: UnificationXref
id: Q6PFX6
db: uniprot

Frizzled-7
type: ProteinReference
xref: PTHR11309:SF31
xref: uniprot Q5BL72 1031
organism: Xenopus tropicalis

Tyrosine-protein kinase
type: ProteinReference
xref: PTHR24418:SF90
xref: uniprot A7MB57 1063
organism: Bos taurus

Frizzled-1
type: ProteinReference
xref: uniprot O70421 1022
xref: PTHR11309:SF81
organism: Mus musculus

uniprot C3XYC4 212
type: UnificationXref
id: C3XYC4
db: uniprot

uniprot W4XTP5 391
type: UnificationXref
id: W4XTP5
db: uniprot

PTHR11937:SF438
type: RelationshipXref
id: PTHR11937:SF438
db: PANTHER Family
relationship type: By Homology

F-actin
type: Protein
entity reference: F-actin
feature: COMPLEX PARTICIPANT BINDING FEATURE s11 sa3 1125
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

uniprot Q9NYQ8 723
type: UnificationXref
id: Q9NYQ8
db: uniprot

uniprot Q5DRD9 640
type: UnificationXref
id: Q5DRD9
db: uniprot

Actin, cytoplasmic 2
type: ProteinReference
xref: uniprot Q6P378 367
xref: PTHR11937:SF192
organism: Xenopus tropicalis

uniprot Q2IBD1 940
type: UnificationXref
id: Q2IBD1
db: uniprot

Protocadherin 8
type: ProteinReference
xref: PTHR24028:SF244
xref: uniprot F1REQ8 491
organism: Danio rerio

AGAP010442-PA
type: ProteinReference
xref: PTHR11309:SF126
xref: uniprot Q7QDV6 1040
organism: Anopheles gambiae

Tyrosine phosphatases
type: ProteinReference
xref: P00472
standard name: Protein-tyrosine phosphatases, non-receptor type 1
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Protein-tyrosine phosphatases, non-receptor type 1 Synonym: PTP1B,PTPN1,Protein phosphotyrosylphosphatase 1B Accession: P00472
comment: ENTITY_REFERENCE_ID_DESC=Cadherin signaling pathway.PROTEIN.GENERIC.Tyrosine_br_phosphatases
member entity reference: Tyrosine-protein phosphatase non-receptor type 1
member entity reference: Protein tyrosine phosphatase non-receptor type 1
member entity reference: Tyrosine-protein phosphatase non-receptor type

Uncharacterized protein
type: ProteinReference
xref: uniprot F0ZK40 238
xref: PTHR11937:SF154
organism: Dictyostelium purpureum

Actin-7
type: ProteinReference
xref: uniprot P0C540 284
xref: PTHR11937:SF408
organism: Oryza sativa

PTHR11937:SF430
type: RelationshipXref
id: PTHR11937:SF430
db: PANTHER Family
relationship type: By Homology

uniprot Q9V5N8 739
type: UnificationXref
id: Q9V5N8
db: uniprot

PTHR11937:SF434
type: RelationshipXref
id: PTHR11937:SF434
db: PANTHER Family
relationship type: By Homology

uniprot P19534 593
type: UnificationXref
id: P19534
db: uniprot

uniprot F7DIA9 1005
type: UnificationXref
id: F7DIA9
db: uniprot

Protein Wnt-1
type: ProteinReference
xref: PTHR12027:SF91
xref: uniprot P24257 912
organism: Danio rerio

uniprot Q9UN71 734
type: UnificationXref
id: Q9UN71
db: uniprot

Transmembrane receptor LIN-17
type: ProteinReference
xref: uniprot G5EDV1 1011
xref: PTHR11309:SF137
organism: Caenorhabditis elegans

CDH16 isoform 1
type: ProteinReference
xref: uniprot A0A2I3RN05 410
xref: PTHR24028:SF1
organism: Pan troglodytes

uniprot Q9Y5H2 770
type: UnificationXref
id: Q9Y5H2
db: uniprot

Protein Wnt-1
type: ProteinReference
xref: PTHR12027:SF101
xref: uniprot P34888 918
organism: Caenorhabditis elegans

uniprot H3FCG4 273
type: UnificationXref
id: H3FCG4
db: uniprot

Protein Wnt-2
type: ProteinReference
xref: PTHR12027:SF77
xref: uniprot P34889 919
organism: Caenorhabditis elegans

uniprot A7MB57 1063
type: UnificationXref
id: A7MB57
db: uniprot

uniprot D3ZCR1 831
type: UnificationXref
id: D3ZCR1
db: uniprot

Cadherin-related family member 1
type: ProteinReference
xref: PTHR24028:SF263
xref: uniprot Q8VHP6 677
organism: Mus musculus

Uncharacterized protein
type: ProteinReference
xref: PTHR24027:SF322
xref: uniprot F6Y191 513
organism: Monodelphis domestica

Casein kinase II subunit beta
type: ProteinReference
xref: PTHR11740:SF0
xref: uniprot Q91398 67
organism: Danio rerio

Tyrosine-protein kinase
type: ProteinReference
xref: PTHR24418:SF90
xref: uniprot Q640S9 1078
organism: Xenopus tropicalis

uniprot F7EZ48 1007
type: UnificationXref
id: F7EZ48
db: uniprot

uniprot Q86UP0 665
type: UnificationXref
id: Q86UP0
db: uniprot

Actin-like protein
type: ProteinReference
xref: uniprot O24426 276
xref: PTHR11937:SF387
organism: Chlamydomonas reinhardtii

PTHR11937:SF421
type: RelationshipXref
id: PTHR11937:SF421
db: PANTHER Family
relationship type: By Homology

FAT atypical cadherin 1
type: ProteinReference
xref: PTHR24026:SF42
xref: uniprot A0A0G2K5L1 395
organism: Rattus norvegicus

Protein Wnt
type: ProteinReference
xref: uniprot F7D1A1 867
xref: PTHR12027:SF94
organism: Xenopus tropicalis

Y142 betacatenin s30 sa17 rs2
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y142
feature location: Y142 betacatenin s30 sa17 rs2 Y142
comment: MODIFICATION_RESIDUE_NAME=Y142
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=2.893781136851091

Receptor tyrosine-protein kinase erbB-3
type: ProteinReference
xref: PTHR24416:SF88
xref: uniprot Q62799 143
organism: Rattus norvegicus

PTHR11937:SF423
type: RelationshipXref
id: PTHR11937:SF423
db: PANTHER Family
relationship type: By Homology

HETERODIMER_ASSOCIATION_LEFT__Cadherin-_betacatenin-RIGHT__Complex__Cadherin_betacatenin_-_r53
type: ComplexAssembly
spontaneous: true
conversion direction: LEFT_TO_RIGHT
xref: HETERODIMER ASSOCIATION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r53 1138
participant stoichiometry: PARTICIPANT STOICHIOMETRY r53 1140
participant stoichiometry: PARTICIPANT STOICHIOMETRY r53 1139
left: betacatenin
left: Cadherin
interaction type: HETERODIMER_ASSOCIATION
right: Complex (Cadherin/betacatenin)

uniprot A0A140T847 807
type: UnificationXref
id: A0A140T847
db: uniprot

uniprot Q9Y5H5 773
type: UnificationXref
id: Q9Y5H5
db: uniprot

Si:dkeyp-80c12.7
type: ProteinReference
xref: PTHR24057:SF8
xref: uniprot B8JIQ1 1081
organism: Danio rerio

PTHR11937:SF416
type: RelationshipXref
id: PTHR11937:SF416
db: PANTHER Family
relationship type: By Homology

CATALYSIS
type: Catalysis
controlled: DISSOCIATION_LEFT__Complex__Cadherin_betacatenin__alphacatenin_F_actin_-RIGHT__Complex__Cadherin_betacatenin_-_Complex__alphacatenin_F_actin_-_r21
controller: Fyn

uniprot C3Z4K3 223
type: UnificationXref
id: C3Z4K3
db: uniprot

uniprot A9TZ58 200
type: UnificationXref
id: A9TZ58
db: uniprot

uniprot F6XVG8 512
type: UnificationXref
id: F6XVG8
db: uniprot

uniprot E2REK7 459
type: UnificationXref
id: E2REK7
db: uniprot

uniprot P25911 1074
type: UnificationXref
id: P25911
db: uniprot

EGFR
type: Protein
entity reference: EGFR
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

uniprot H3F5B4 272
type: UnificationXref
id: H3F5B4
db: uniprot

uniprot E9Q5G2 465
type: UnificationXref
id: E9Q5G2
db: uniprot

uniprot D4A9D7 838
type: UnificationXref
id: D4A9D7
db: uniprot

uniprot D4A3W9 837
type: UnificationXref
id: D4A3W9
db: uniprot

S betacatenin s5 sa1 rs4
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY S
feature location: S betacatenin s5 sa1 rs4 S
comment: MODIFICATION_RESIDUE_NAME=S
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=1.6575346654708816

Frizzled-2
type: ProteinReference
xref: PTHR11309:SF126
xref: uniprot Q9VVX3 1058
organism: Drosophila melanogaster

uniprot Q9UP38 1057
type: UnificationXref
id: Q9UP38
db: uniprot

PTHR12027:SF89
type: RelationshipXref
id: PTHR12027:SF89
db: PANTHER Family
relationship type: By Homology

uniprot Q9Y5G5 764
type: UnificationXref
id: Q9Y5G5
db: uniprot

PTHR12027:SF88
type: RelationshipXref
id: PTHR12027:SF88
db: PANTHER Family
relationship type: By Homology

PTHR12027:SF87
type: RelationshipXref
id: PTHR12027:SF87
db: PANTHER Family
relationship type: By Homology

Cadherin-2
type: ProteinReference
xref: PTHR24027:SF79
xref: uniprot P19534 593
organism: Bos taurus

uniprot Q67G20 362
type: UnificationXref
id: Q67G20
db: uniprot

uniprot F6TUR3 251
type: UnificationXref
id: F6TUR3
db: uniprot

PTHR12027:SF92
type: RelationshipXref
id: PTHR12027:SF92
db: PANTHER Family
relationship type: By Homology

Cadherin-11
type: ProteinReference
xref: uniprot P55288 607
xref: PTHR24027:SF85
organism: Mus musculus

PTHR12027:SF93
type: RelationshipXref
id: PTHR12027:SF93
db: PANTHER Family
relationship type: By Homology

Cadherin-11
type: ProteinReference
xref: uniprot P55287 606
xref: PTHR24027:SF85
organism: Homo sapiens

Cadherin-8
type: ProteinReference
xref: uniprot P55286 605
xref: PTHR24027:SF273
organism: Homo sapiens

PTHR12027:SF91
type: RelationshipXref
id: PTHR12027:SF91
db: PANTHER Family
relationship type: By Homology

Cadherin-6
type: ProteinReference
xref: uniprot P55285 604
xref: PTHR24027:SF322
organism: Homo sapiens

Protein Wnt-11
type: ProteinReference
xref: PTHR12027:SF34
xref: uniprot O73864 900
organism: Danio rerio

Uncharacterized protein
type: ProteinReference
xref: uniprot F7DGM2 530
xref: PTHR24027:SF81
organism: Macaca mulatta

PTHR12027:SF94
type: RelationshipXref
id: PTHR12027:SF94
db: PANTHER Family
relationship type: By Homology

Tyrosine-protein kinase
type: ProteinReference
xref: uniprot F1P8N3 156
xref: PTHR24418:SF227
organism: Canis lupus familiaris

Cadherin-12
type: ProteinReference
xref: uniprot P55289 608
xref: PTHR24027:SF96
organism: Homo sapiens

Cadherin-6
type: ProteinReference
xref: uniprot P55280 600
xref: PTHR24027:SF322
organism: Rattus norvegicus

uniprot P33450 597
type: UnificationXref
id: P33450
db: uniprot

Cadherin-5
type: ProteinReference
xref: PTHR24027:SF89
xref: uniprot P55284 603
organism: Mus musculus

Cadherin-4
type: ProteinReference
xref: uniprot P55283 602
xref: PTHR24027:SF81
organism: Homo sapiens

Cadherin-17
type: ProteinReference
xref: PTHR24027:SF419
xref: uniprot P55281 601
organism: Rattus norvegicus

uniprot E1BDG5 840
type: UnificationXref
id: E1BDG5
db: uniprot

uniprot Q08464 1027
type: UnificationXref
id: Q08464
db: uniprot

Protein Wnt
type: ProteinReference
xref: uniprot Q9YGX6 970
xref: PTHR12027:SF33
organism: Gallus gallus

Catenin beta-1
type: ProteinReference
xref: uniprot B6V8E6 69
xref: PTHR45976:SF4
organism: Canis lupus familiaris

uniprot Q9H251 714
type: UnificationXref
id: Q9H251
db: uniprot

FZD1 protein
type: ProteinReference
xref: PTHR11309:SF81
xref: uniprot A7MB15 979
organism: Bos taurus

PTHR12027:SF98
type: RelationshipXref
id: PTHR12027:SF98
db: PANTHER Family
relationship type: By Homology

uniprot Q9Y5I0 778
type: UnificationXref
id: Q9Y5I0
db: uniprot

00696
type: UnificationXref
id: MOD:00696
db: mod

uniprot F1M7E5 474
type: UnificationXref
id: F1M7E5
db: uniprot

uniprot A0A2I3TB47 417
type: UnificationXref
id: A0A2I3TB47
db: uniprot

Catenin beta-1
type: ProteinReference
xref: uniprot F7GNE4 74
xref: PTHR45976:SF4
organism: Macaca mulatta

ncbitaxon 45351 11
type: UnificationXref
id: 45351
db: ncbitaxon

Frizzled-6
type: ProteinReference
xref: uniprot Q8WMU5 1045
xref: PTHR11309:SF75
organism: Canis lupus familiaris

P120 s121 a174 rs1
type: ModificationFeature
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=
comment: MODIFICATION_RESIDUE_ANGLE=3.14

Casein kinase II subunit beta
type: ProteinReference
xref: PTHR11740:SF0
xref: uniprot F6T6M8 31
organism: Monodelphis domestica

uniprot F7E9U1 1006
type: UnificationXref
id: F7E9U1
db: uniprot

uniprot F1MHH5 479
type: UnificationXref
id: F1MHH5
db: uniprot

Cadherin-15
type: ProteinReference
xref: uniprot P55291 610
xref: PTHR24027:SF300
organism: Homo sapiens

uniprot A0A3Q3B1W2 102
type: UnificationXref
id: A0A3Q3B1W2
db: uniprot

Cadherin-13
type: ProteinReference
xref: uniprot P55290 609
xref: PTHR24027:SF80
organism: Homo sapiens

uniprot Q3SWX5 628
type: UnificationXref
id: Q3SWX5
db: uniprot

Cadherin-2
type: ProteinReference
xref: PTHR24027:SF79
xref: uniprot Q9Z1Y3 785
organism: Rattus norvegicus

uniprot F7HPU3 552
type: UnificationXref
id: F7HPU3
db: uniprot

Fat-like cadherin-related tumor suppressor homolog
type: ProteinReference
xref: PTHR24026:SF101
xref: uniprot Q9VW71 744
organism: Drosophila melanogaster

Physcomitrella patens
type: BioSource
xref: ncbitaxon 3218 196

Putative actin-9
type: ProteinReference
xref: PTHR11937:SF483
xref: uniprot P93738 341
organism: Arabidopsis thaliana

uniprot F7DI28 869
type: UnificationXref
id: F7DI28
db: uniprot

uniprot F7EXZ6 537
type: UnificationXref
id: F7EXZ6
db: uniprot

Protocadherin Fat 2
type: ProteinReference
xref: uniprot Q5F226 645
xref: PTHR24026:SF37
organism: Mus musculus

Actin, cytoplasmic 2
type: ProteinReference
xref: PTHR11937:SF414
xref: uniprot P63259 320
organism: Rattus norvegicus

Actin-related protein 2-B
type: ProteinReference
xref: uniprot Q56A35 352
xref: PTHR11937:SF149
organism: Danio rerio

ncbitaxon 5664 388
type: UnificationXref
id: 5664
db: ncbitaxon

Cadherin 18
type: ProteinReference
xref: uniprot F7ABP2 520
xref: PTHR24027:SF106
organism: Monodelphis domestica

Cadherin-11 preproprotein
type: ProteinReference
xref: PTHR24027:SF85
xref: uniprot F7GFF0 541
organism: Macaca mulatta

Actin, cytoplasmic 2
type: ProteinReference
xref: uniprot P63258 319
xref: PTHR11937:SF414
organism: Bos taurus

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF84
xref: uniprot F7H7P6 874
organism: Macaca mulatta

betacatenin s94 a133 rs5
type: ModificationFeature
modification type: MODIFICATION FEATURE ubiquitinated
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=4.653633157668967
comment: MODIFICATION_RESIDUE_NAME=

Actin-87E
type: ProteinReference
xref: uniprot P10981 287
xref: PTHR11937:SF397
organism: Drosophila melanogaster

Actin-3
type: ProteinReference
xref: PTHR11937:SF387
xref: uniprot P0DM42 286
organism: Caenorhabditis elegans

Actin-2
type: ProteinReference
xref: PTHR11937:SF470
xref: uniprot P10984 288
organism: Caenorhabditis elegans

uniprot Q7PXZ8 375
type: UnificationXref
id: Q7PXZ8
db: uniprot

uniprot Q9Y5E6 750
type: UnificationXref
id: Q9Y5E6
db: uniprot

uniprot Q9H1J5 959
type: UnificationXref
id: Q9H1J5
db: uniprot

PTHR12027:SF75
type: RelationshipXref
id: PTHR12027:SF75
db: PANTHER Family
relationship type: By Homology

uniprot A0A3Q1MZ99 101
type: UnificationXref
id: A0A3Q1MZ99
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F7HA59 548
xref: PTHR24028:SF46
organism: Macaca mulatta

PTHR12027:SF72
type: RelationshipXref
id: PTHR12027:SF72
db: PANTHER Family
relationship type: By Homology

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF70
xref: uniprot A0A140T847 807
organism: Bos taurus

ncbitaxon 7165 62
type: UnificationXref
id: 7165
db: ncbitaxon

uniprot H2QD96 885
type: UnificationXref
id: H2QD96
db: uniprot

PTHR12027:SF73
type: RelationshipXref
id: PTHR12027:SF73
db: PANTHER Family
relationship type: By Homology

uniprot Q5DRB3 629
type: UnificationXref
id: Q5DRB3
db: uniprot

PTHR12027:SF70
type: RelationshipXref
id: PTHR12027:SF70
db: PANTHER Family
relationship type: By Homology

uniprot P22724 908
type: UnificationXref
id: P22724
db: uniprot

uniprot Q7PPB2 652
type: UnificationXref
id: Q7PPB2
db: uniprot

Tyrosine-protein kinase
type: ProteinReference
xref: uniprot H2R453 1070
organism: Pan troglodytes

Frizzled class receptor 5
type: ProteinReference
xref: PTHR11309:SF141
xref: uniprot F6QAW3 995
organism: Xenopus tropicalis

Casein kinase II subunit alpha
type: ProteinReference
xref: uniprot P19139 47
xref: PTHR24054:SF16
organism: Rattus norvegicus

DISSOCIATION
type: RelationshipTypeVocabulary

Actin, gamma-enteric smooth muscle
type: ProteinReference
xref: uniprot P63267 323
xref: PTHR11937:SF445
organism: Homo sapiens

Uncharacterized protein
type: ProteinReference
xref: PTHR24028:SF119
xref: uniprot F7GRQ8 544
organism: Macaca mulatta

Actin, cytoplasmic 2
type: ProteinReference
xref: PTHR11937:SF414
xref: uniprot P63261 322
organism: Homo sapiens

T112 betacatenin s3 a16 rs3
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY T112
feature location: T112 betacatenin s3 a16 rs3 T112
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=T112
comment: MODIFICATION_RESIDUE_ANGLE=-0.0

uniprot F6WBD5 73
type: UnificationXref
id: F6WBD5
db: uniprot

Actin, cytoplasmic 2
type: ProteinReference
xref: PTHR11937:SF414
xref: uniprot P63260 321
organism: Mus musculus

Uncharacterized protein
type: ProteinReference
xref: uniprot F7GRQ5 543
xref: PTHR24028:SF12
organism: Macaca mulatta

STATE_TRANSITION_LEFT__Fer-RIGHT__Fer-_r12
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r12 1176
participant stoichiometry: PARTICIPANT STOICHIOMETRY r12 1175
left: Fer
interaction type: STATE_TRANSITION
right: Fer

uniprot P49337 926
type: UnificationXref
id: P49337
db: uniprot

Actin, gamma-enteric smooth muscle
type: ProteinReference
xref: PTHR11937:SF445
xref: uniprot P63268 324
organism: Mus musculus

Actin, gamma-enteric smooth muscle
type: ProteinReference
xref: PTHR11937:SF201
xref: uniprot P63269 325
organism: Rattus norvegicus

uniprot Q6XNL8 371
type: UnificationXref
id: Q6XNL8
db: uniprot

PTHR12027:SF77
type: RelationshipXref
id: PTHR12027:SF77
db: PANTHER Family
relationship type: By Homology

uniprot F1P7Y5 485
type: UnificationXref
id: F1P7Y5
db: uniprot

PTHR12027:SF76
type: RelationshipXref
id: PTHR12027:SF76
db: PANTHER Family
relationship type: By Homology

PTHR12027:SF78
type: RelationshipXref
id: PTHR12027:SF78
db: PANTHER Family
relationship type: By Homology

Casein kinase II subunit beta'
type: ProteinReference
xref: PTHR11740:SF0
xref: uniprot O96863 41
organism: Drosophila melanogaster

PTHR12027:SF84
type: RelationshipXref
id: PTHR12027:SF84
db: PANTHER Family
relationship type: By Homology

Actin, gamma-enteric smooth muscle
type: ProteinReference
xref: PTHR11937:SF445
xref: uniprot P63270 326
organism: Gallus gallus

PTHR12027:SF86
type: RelationshipXref
id: PTHR12027:SF86
db: PANTHER Family
relationship type: By Homology

Cadherin 3
type: ProteinReference
xref: PTHR24027:SF267
xref: uniprot F6QAX3 494
organism: Xenopus tropicalis

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF82
xref: uniprot F7H7P8 875
organism: Macaca mulatta

PTHR12027:SF81
type: RelationshipXref
id: PTHR12027:SF81
db: PANTHER Family
relationship type: By Homology

FAT atypical cadherin 2
type: ProteinReference
xref: uniprot H2QRU2 573
xref: PTHR24026:SF37
organism: Pan troglodytes

PTHR12027:SF82
type: RelationshipXref
id: PTHR12027:SF82
db: PANTHER Family
relationship type: By Homology

Frizzled-7
type: ProteinReference
xref: uniprot A0A1D5PEJ9 973
xref: PTHR11309:SF31
organism: Gallus gallus

uniprot G3V987 558
type: UnificationXref
id: G3V987
db: uniprot

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF82
xref: uniprot D3ZCR1 831
organism: Rattus norvegicus

ncbitaxon 6239 46
type: UnificationXref
id: 6239
db: ncbitaxon

uniprot A0A1D5QQ23 120
type: UnificationXref
id: A0A1D5QQ23
db: uniprot

Protein Wnt
type: ProteinReference
xref: uniprot X1WEJ5 971
xref: PTHR12027:SF73
organism: Danio rerio

Protocadherin gamma-A5
type: ProteinReference
xref: uniprot Q9Y5G8 767
xref: PTHR24028:SF105
organism: Homo sapiens

uniprot Q8TAB3 675
type: UnificationXref
id: Q8TAB3
db: uniprot

Protocadherin gamma-A6
type: ProteinReference
xref: uniprot Q9Y5G7 766
xref: PTHR24028:SF107
organism: Homo sapiens

Protocadherin gamma-A7
type: ProteinReference
xref: PTHR24028:SF56
xref: uniprot Q9Y5G6 765
organism: Homo sapiens

Protocadherin gamma-A8
type: ProteinReference
xref: uniprot Q9Y5G5 764
xref: PTHR24028:SF72
organism: Homo sapiens

Protocadherin gamma-B1
type: ProteinReference
xref: uniprot Q9Y5G3 763
xref: PTHR24028:SF106
organism: Homo sapiens

Glycogen synthase kinase 3
type: ProteinReference
xref: PTHR24057:SF8
xref: uniprot Q9YH60 1089
organism: Danio rerio

Protocadherin gamma-B2
type: ProteinReference
xref: uniprot Q9Y5G2 762
xref: PTHR24028:SF144
organism: Homo sapiens

PTHR45976:SF4
type: RelationshipXref
id: PTHR45976:SF4
db: PANTHER Family
relationship type: By Homology

Protein Wnt
type: ProteinReference
xref: uniprot F1N6L8 852
xref: PTHR12027:SF78
organism: Bos taurus

uniprot A0A2I3RS45 792
type: UnificationXref
id: A0A2I3RS45
db: uniprot

uniprot Q9UN70 733
type: UnificationXref
id: Q9UN70
db: uniprot

PTHR24027:SF322
type: RelationshipXref
id: PTHR24027:SF322
db: PANTHER Family
relationship type: By Homology

PTHR24027:SF323
type: RelationshipXref
id: PTHR24027:SF323
db: PANTHER Family
relationship type: By Homology

Protein Wnt
type: ProteinReference
xref: uniprot Q9DEB8 957
xref: PTHR12027:SF78
organism: Gallus gallus

Cadherin-99C
type: ProteinReference
xref: uniprot Q9VAF5 740
xref: PTHR24026:SF93
organism: Drosophila melanogaster

Protocadherin beta-13
type: ProteinReference
xref: PTHR24028:SF61
xref: uniprot Q9Y5F0 754
organism: Homo sapiens

uniprot C3XYD4 218
type: UnificationXref
id: C3XYD4
db: uniprot

uniprot Q5R1X3 359
type: UnificationXref
id: Q5R1X3
db: uniprot

Complex (Wnt/Frizzled)
type: Complex
component stoichiometry: Frizzled s27 sa21 STOICHIOMETRY ID COMPLEX
component stoichiometry: Wnt s26 sa20 STOICHIOMETRY ID COMPLEX
component: Frizzled
component: Wnt
feature: ACTIVE 162
feature: COMPLEX BINDING FEATURE s106 a149 1136
feature: COMPLEX BINDING FEATURE s106 a149 1134
cellular location: cytoplasm

S betacatenin s28 sa22 rs4
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY S
feature location: S betacatenin s28 sa22 rs4 S
comment: MODIFICATION_RESIDUE_NAME=S
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=1.6575346654708816

Protocadherin beta-16-like
type: ProteinReference
xref: uniprot G3V987 558
xref: PTHR24028:SF71
organism: Rattus norvegicus

Protocadherin gamma-C5
type: ProteinReference
xref: uniprot Q9Y5F6 758
xref: PTHR24028:SF258
organism: Homo sapiens

Receptor protein-tyrosine kinase
type: ProteinReference
xref: PTHR24416:SF90
xref: uniprot F7GAV2 128
organism: Ornithorhynchus anatinus

Protocadherin gamma-B7
type: ProteinReference
xref: PTHR24028:SF113
xref: uniprot Q9Y5F8 760
organism: Homo sapiens

uniprot C3ZHN4 225
type: UnificationXref
id: C3ZHN4
db: uniprot

Protocadherin gamma-C4
type: ProteinReference
xref: PTHR24028:SF272
xref: uniprot Q9Y5F7 759
organism: Homo sapiens

Protocadherin beta-11
type: ProteinReference
xref: uniprot Q9Y5F2 756
xref: PTHR24028:SF286
organism: Homo sapiens

Protocadherin beta-12
type: ProteinReference
xref: uniprot Q9Y5F1 755
xref: PTHR24028:SF91
organism: Homo sapiens

Uncharacterized protein
type: ProteinReference
xref: PTHR10373:SF11
xref: uniprot F6ZBJ4 107
organism: Monodelphis domestica

Uncharacterized protein
type: ProteinReference
xref: PTHR24027:SF96
xref: uniprot F7HPS8 551
organism: Macaca mulatta

Protocadherin beta-1
type: ProteinReference
xref: uniprot Q9Y5F3 757
xref: PTHR24028:SF12
organism: Homo sapiens

Protein Wnt
type: ProteinReference
xref: uniprot A6H6X8 819
xref: PTHR12027:SF93
organism: Bos taurus

uniprot P39038 599
type: UnificationXref
id: P39038
db: uniprot

uniprot Q9BZA7 710
type: UnificationXref
id: Q9BZA7
db: uniprot

Actin, beta like 2
type: ProteinReference
xref: uniprot H2QE24 271
xref: PTHR11937:SF278
organism: Pan troglodytes

Protocadherin gamma-B6
type: ProteinReference
xref: PTHR24028:SF66
xref: uniprot Q9Y5F9 761
organism: Homo sapiens

uniprot F7BV42 1068
type: UnificationXref
id: F7BV42
db: uniprot

Frizzled-4
type: ProteinReference
xref: PTHR11309:SF23
xref: uniprot Q9QZH0 1053
organism: Rattus norvegicus

Lymphoid enhancer-binding factor 1
type: ProteinReference
xref: PTHR10373:SF11
xref: uniprot P27782 110
organism: Mus musculus

uniprot Q10AZ4 343
type: UnificationXref
id: Q10AZ4
db: uniprot

Actin-5C
type: ProteinReference
xref: uniprot P10987 290
xref: PTHR11937:SF387
organism: Drosophila melanogaster

Actin-4
type: ProteinReference
xref: uniprot P10986 289
xref: PTHR11937:SF471
organism: Caenorhabditis elegans

uniprot Q9NPG1 1051
type: UnificationXref
id: Q9NPG1
db: uniprot

uniprot Q93098 956
type: UnificationXref
id: Q93098
db: uniprot

Actin
type: ProteinReference
xref: uniprot P10989 291
xref: PTHR11937:SF387
organism: Schizosaccharomyces pombe

uniprot Q8VHP6 677
type: UnificationXref
id: Q8VHP6
db: uniprot

Protocadherin-related 15
type: ProteinReference
xref: uniprot F1LXN4 470
xref: PTHR24028:SF11
organism: Rattus norvegicus

Protocadherin alpha-1
type: ProteinReference
xref: PTHR24028:SF92
xref: uniprot Q9Y5I3 781
organism: Homo sapiens

Protocadherin alpha-10
type: ProteinReference
xref: uniprot Q9Y5I2 780
xref: PTHR24028:SF124
organism: Homo sapiens

Protocadherin alpha-11
type: ProteinReference
xref: PTHR24028:SF68
xref: uniprot Q9Y5I1 779
organism: Homo sapiens

Protocadherin alpha-13
type: ProteinReference
xref: uniprot Q9Y5I0 778
xref: PTHR24028:SF101
organism: Homo sapiens

uniprot F1LM93 1065
type: UnificationXref
id: F1LM93
db: uniprot

Protocadherin alpha-C2
type: ProteinReference
xref: uniprot Q9Y5I4 782
xref: PTHR24028:SF119
organism: Homo sapiens

uniprot F2Z3R5 492
type: UnificationXref
id: F2Z3R5
db: uniprot

S T Cadherin s24 sa24 rs2
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY S T
feature location: S T Cadherin s24 sa24 rs2 S T
comment: MODIFICATION_RESIDUE_NAME=S/T
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=0.09

uniprot E2QXQ3 843
type: UnificationXref
id: E2QXQ3
db: uniprot

uniprot K7AZD4 1018
type: UnificationXref
id: K7AZD4
db: uniprot

Receptor protein-tyrosine kinase
type: ProteinReference
xref: PTHR24416:SF90
xref: uniprot A0A2I3RF60 121
organism: Pan troglodytes

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A2A6CRA8 167
xref: PTHR11937:SF387
organism: Pristionchus pacificus

a133_degraded
type: PhysicalEntity
cellular location: cytoplasm
comment: SPECIES_TYPE=DEGRADED

uniprot A0A2I3SIV3 416
type: UnificationXref
id: A0A2I3SIV3
db: uniprot

PCDH12 isoform 1
type: ProteinReference
xref: uniprot H2QRP0 572
xref: PTHR24028:SF42
organism: Pan troglodytes

uniprot E2R971 458
type: UnificationXref
id: E2R971
db: uniprot

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF91
xref: uniprot D4A9J2 839
organism: Rattus norvegicus

uniprot Q9WUD9 154
type: UnificationXref
id: Q9WUD9
db: uniprot

uniprot H2QRN2 570
type: UnificationXref
id: H2QRN2
db: uniprot

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF88
xref: uniprot H2R817 888
organism: Pan troglodytes

uniprot C3Z2P0 829
type: UnificationXref
id: C3Z2P0
db: uniprot

uniprot E1BKL2 842
type: UnificationXref
id: E1BKL2
db: uniprot

Protein Wnt-5
type: ProteinReference
xref: uniprot P28466 917
xref: PTHR12027:SF77
organism: Drosophila melanogaster

Protein Wnt-2
type: ProteinReference
xref: PTHR12027:SF112
xref: uniprot P28465 916
organism: Drosophila melanogaster

Cadherin
type: Protein
entity reference: Cadherin
feature: S T Cadherin s24 sa24 rs2
feature: COMPLEX PARTICIPANT BINDING FEATURE s24 sa24 1117
feature: Y Cadherin s24 sa24 rs1
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

Protocadherin gamma-A3
type: ProteinReference
xref: PTHR24028:SF234
xref: uniprot Q9Y5H0 768
organism: Homo sapiens

PTHR12027:SF33
type: RelationshipXref
id: PTHR12027:SF33
db: PANTHER Family
relationship type: By Homology

PTHR12027:SF34
type: RelationshipXref
id: PTHR12027:SF34
db: PANTHER Family
relationship type: By Homology

Protocadherin gamma-A11
type: ProteinReference
xref: PTHR24028:SF84
xref: uniprot Q9Y5H2 770
organism: Homo sapiens

Protocadherin gamma-A2
type: ProteinReference
xref: uniprot Q9Y5H1 769
xref: PTHR24028:SF134
organism: Homo sapiens

uniprot Q9UN66 731
type: UnificationXref
id: Q9UN66
db: uniprot

uniprot Q91UZ8 683
type: UnificationXref
id: Q91UZ8
db: uniprot

Protocadherin gamma-A1
type: ProteinReference
xref: PTHR24028:SF108
xref: uniprot Q9Y5H4 772
organism: Homo sapiens

Protocadherin gamma-A10
type: ProteinReference
xref: uniprot Q9Y5H3 771
xref: PTHR24028:SF110
organism: Homo sapiens

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A1D5REM7 99
xref: PTHR10373:SF11
organism: Macaca mulatta

Protocadherin alpha-8
type: ProteinReference
xref: PTHR24028:SF133
xref: uniprot Q9Y5H6 774
organism: Homo sapiens

Non-muscle actin 6.2
type: ProteinReference
xref: uniprot B3S5E4 208
xref: PTHR11937:SF387
organism: Trichoplax adhaerens

Protein Wnt-10a
type: ProteinReference
xref: PTHR12027:SF89
xref: uniprot P70701 935
organism: Mus musculus

Protocadherin alpha-9
type: ProteinReference
xref: PTHR24028:SF255
xref: uniprot Q9Y5H5 773
organism: Homo sapiens

uniprot Q8CHL0 1042
type: UnificationXref
id: Q8CHL0
db: uniprot

Protocadherin alpha-3
type: ProteinReference
xref: uniprot Q9Y5H8 776
xref: PTHR24028:SF93
organism: Homo sapiens

Protocadherin alpha-5
type: ProteinReference
xref: uniprot Q9Y5H7 775
xref: PTHR24028:SF111
organism: Homo sapiens

uniprot P18266 1086
type: UnificationXref
id: P18266
db: uniprot

Protocadherin alpha-2
type: ProteinReference
xref: uniprot Q9Y5H9 777
xref: PTHR24028:SF60
organism: Homo sapiens

uniprot F6XMD3 864
type: UnificationXref
id: F6XMD3
db: uniprot

Abnormal cell lineage protein 44
type: ProteinReference
xref: PTHR12027:SF112
xref: uniprot Q27886 938
organism: Caenorhabditis elegans

uniprot O60330 581
type: UnificationXref
id: O60330
db: uniprot

uniprot P08182 44
type: UnificationXref
id: P08182
db: uniprot

Beta-actin-like protein 2
type: ProteinReference
xref: PTHR11937:SF168
xref: uniprot Q8BFZ3 380
organism: Mus musculus

PTHR24026:SF51
type: RelationshipXref
id: PTHR24026:SF51
db: PANTHER Family
relationship type: By Homology

uniprot F7GH85 873
type: UnificationXref
id: F7GH85
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF446
xref: uniprot C3ZTX6 227
organism: Branchiostoma floridae

PTHR24027:SF419
type: RelationshipXref
id: PTHR24027:SF419
db: PANTHER Family
relationship type: By Homology

uniprot Q9Y5H8 776
type: UnificationXref
id: Q9Y5H8
db: uniprot

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF91
xref: uniprot E2RTG8 846
organism: Canis lupus familiaris

Actin-57B
type: ProteinReference
xref: uniprot P53501 306
xref: PTHR11937:SF397
organism: Drosophila melanogaster

Casein kinase II subunit alpha 3
type: ProteinReference
xref: uniprot Q8NEV1 64
xref: PTHR24054:SF16
organism: Homo sapiens

Fer
type: Protein
entity reference: Fer
feature: ACTIVE 162
feature: Y Fer s64 a7 rs1
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

betacatenin s5 sa1 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

PTHR24028:SF272
type: RelationshipXref
id: PTHR24028:SF272
db: PANTHER Family
relationship type: By Homology

Protein Wnt-7a
type: ProteinReference
xref: PTHR12027:SF78
xref: uniprot O00755 895
organism: Homo sapiens

Y142 betacatenin s5 sa1 rs2
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y142
feature location: Y142 betacatenin s5 sa1 rs2 Y142
modification type: phosphorylated residue
comment: MODIFICATION_RESIDUE_NAME=Y142
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=2.893781136851091

TRANSPORT
type: RelationshipTypeVocabulary

uniprot Q92050 954
type: UnificationXref
id: Q92050
db: uniprot

Protocadherin beta-9
type: ProteinReference
xref: uniprot Q5DRC4 630
xref: PTHR24028:SF128
organism: Pan troglodytes

uniprot Q54GX7 348
type: UnificationXref
id: Q54GX7
db: uniprot

Protocadherin beta-7
type: ProteinReference
xref: PTHR24028:SF69
xref: uniprot Q5DRC7 632
organism: Pan troglodytes

AGAP009716-PA (Fragment)
type: ProteinReference
xref: PTHR24027:SF422
xref: uniprot Q7Q1M9 659
organism: Anopheles gambiae

Protocadherin beta-8
type: ProteinReference
xref: PTHR24028:SF150
xref: uniprot Q5DRC6 631
organism: Pan troglodytes

PTHR24026:SF49
type: RelationshipXref
id: PTHR24026:SF49
db: PANTHER Family
relationship type: By Homology

uniprot A8WS32 189
type: UnificationXref
id: A8WS32
db: uniprot

Sclerotinia sclerotiorum
type: BioSource
xref: ncbitaxon 665079 178

PTHR24026:SF42
type: RelationshipXref
id: PTHR24026:SF42
db: PANTHER Family
relationship type: By Homology

TCF7L1 isoform 2
type: ProteinReference
xref: PTHR10373:SF25
xref: uniprot H2QI87 109
organism: Pan troglodytes

Epidermal growth factor receptor
type: ProteinReference
xref: uniprot P00533 132
xref: PTHR24416:SF91
organism: Homo sapiens

HETERODIMER_ASSOCIATION_LEFT__betacatenin-_TCF_LEF-RIGHT__Complex__betacatenin_TCF_LEF_-_r50
type: ComplexAssembly
spontaneous: true
conversion direction: LEFT_TO_RIGHT
xref: HETERODIMER ASSOCIATION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r50 1152
participant stoichiometry: PARTICIPANT STOICHIOMETRY r50 1153
participant stoichiometry: PARTICIPANT STOICHIOMETRY r50 1151
left: betacatenin
left: TCF/LEF
interaction type: HETERODIMER_ASSOCIATION
right: Complex (betacatenin/TCF/LEF)

uniprot F1MW29 481
type: UnificationXref
id: F1MW29
db: uniprot

uniprot F7D1A1 867
type: UnificationXref
id: F7D1A1
db: uniprot

Protein Wnt
type: ProteinReference
xref: uniprot B1WBR9 824
xref: PTHR12027:SF87
organism: Rattus norvegicus

uniprot F1MP23 991
type: UnificationXref
id: F1MP23
db: uniprot

uniprot Q5DRD2 635
type: UnificationXref
id: Q5DRD2
db: uniprot

PTHR24028:SF260
type: RelationshipXref
id: PTHR24028:SF260
db: PANTHER Family
relationship type: By Homology

PTHR24028:SF263
type: RelationshipXref
id: PTHR24028:SF263
db: PANTHER Family
relationship type: By Homology

PTHR24028:SF265
type: RelationshipXref
id: PTHR24028:SF265
db: PANTHER Family
relationship type: By Homology

uniprot H2QQP8 569
type: UnificationXref
id: H2QQP8
db: uniprot

Protocadherin gamma-A7
type: ProteinReference
xref: PTHR24028:SF56
xref: uniprot Q5DRB3 629
organism: Pan troglodytes

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A1D5Q2V8 402
xref: PTHR24028:SF11
organism: Macaca mulatta

uniprot P21860 136
type: UnificationXref
id: P21860
db: uniprot

Y Cadherin s1 a10 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y
feature location: Y Cadherin s1 a10 rs1 Y
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=Y
comment: MODIFICATION_RESIDUE_ANGLE=3.14

uniprot Q91XW9 688
type: UnificationXref
id: Q91XW9
db: uniprot

Casein kinase II subunit beta
type: ProteinReference
xref: PTHR11740:SF0
xref: uniprot Q967X2 68
organism: Ciona intestinalis

CDHR1 isoform 1
type: ProteinReference
xref: PTHR24028:SF263
xref: uniprot A0A2J8KIM7 421
organism: Pan troglodytes

uniprot Q9Y5E3 747
type: UnificationXref
id: Q9Y5E3
db: uniprot

uniprot Q9UN72 735
type: UnificationXref
id: Q9UN72
db: uniprot

Proto-oncogene tyrosine-protein kinase Src
type: ProteinReference
xref: PTHR24418:SF53
xref: uniprot P00523 151
organism: Gallus gallus

Cadherin 12
type: ProteinReference
xref: PTHR24027:SF96
xref: uniprot F6VEV5 506
organism: Ornithorhynchus anatinus

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF77
xref: uniprot Q9U6V0 965
organism: Ciona intestinalis

Protein Wnt
type: ProteinReference
xref: uniprot A0A2I3TI13 812
xref: PTHR12027:SF92
organism: Pan troglodytes

Entamoeba histolytica
type: BioSource
xref: ncbitaxon 5759 204

Casein kinase II subunit beta
type: ProteinReference
xref: PTHR11740:SF0
xref: uniprot B7QIS2 16
organism: Ixodes scapularis

ISS
type: EvidenceCodeVocabulary
xref: eco ECO:0000250 6

PTHR24027:SF96
type: RelationshipXref
id: PTHR24027:SF96
db: PANTHER Family
relationship type: By Homology

DISSOCIATION_LEFT__Complex__Cadherin_betacatenin__alphacatenin_F_actin_-RIGHT__Cadherin-_Complex__betacatenin_alphacatenin__F_actin_-_r43
type: ComplexAssembly
spontaneous: false
conversion direction: LEFT_TO_RIGHT
xref: DISSOCIATION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r43 1179
participant stoichiometry: PARTICIPANT STOICHIOMETRY r43 1177
participant stoichiometry: PARTICIPANT STOICHIOMETRY r43 1178
left: Complex (Cadherin/betacatenin/ alphacatenin/F-actin)
interaction type: DISSOCIATION
right: Cadherin
right: Complex (betacatenin/alphacatenin/ F-actin)

PTHR24028:SF295
type: RelationshipXref
id: PTHR24028:SF295
db: PANTHER Family
relationship type: By Homology

Protocadherin beta-10
type: ProteinReference
xref: PTHR24028:SF54
xref: uniprot Q5DRD9 640
organism: Pan troglodytes

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A1D5PMG0 399
xref: PTHR24028:SF248
organism: Gallus gallus

PTHR24027:SF91
type: RelationshipXref
id: PTHR24027:SF91
db: PANTHER Family
relationship type: By Homology

Protein Wnt-6
type: ProteinReference
xref: uniprot Q9Y6F9 969
xref: PTHR12027:SF72
organism: Homo sapiens

Protocadherin-19
type: ProteinReference
xref: uniprot Q8TAB3 675
xref: PTHR24028:SF40
organism: Homo sapiens

uniprot E2R858 457
type: UnificationXref
id: E2R858
db: uniprot

ncbitaxon 3702 303
type: UnificationXref
id: 3702
db: ncbitaxon

Frizzled class receptor 3
type: ProteinReference
xref: uniprot F6RPG1 998
xref: PTHR11309:SF22
organism: Xenopus tropicalis

PTHR24027:SF89
type: RelationshipXref
id: PTHR24027:SF89
db: PANTHER Family
relationship type: By Homology

uniprot O15943 577
type: UnificationXref
id: O15943
db: uniprot

PTHR24028:SF298
type: RelationshipXref
id: PTHR24028:SF298
db: PANTHER Family
relationship type: By Homology

uniprot H2Q569 884
type: UnificationXref
id: H2Q569
db: uniprot

Protocadherin beta-1
type: ProteinReference
xref: uniprot Q5DRE0 641
xref: PTHR24028:SF12
organism: Pan troglodytes

uniprot Q9Y5F3 757
type: UnificationXref
id: Q9Y5F3
db: uniprot

uniprot Q9P2E7 724
type: UnificationXref
id: Q9P2E7
db: uniprot

Protein Wnt
type: ProteinReference
xref: uniprot F6PMQ6 855
xref: PTHR12027:SF33
organism: Monodelphis domestica

uniprot G3V7U3 878
type: UnificationXref
id: G3V7U3
db: uniprot

PTHR24028:SF284
type: RelationshipXref
id: PTHR24028:SF284
db: PANTHER Family
relationship type: By Homology

uniprot P53489 301
type: UnificationXref
id: P53489
db: uniprot

Monodelphis domestica
type: BioSource
xref: ncbitaxon 13616 28

Actin, cytoskeletal 3B
type: ProteinReference
xref: PTHR11937:SF387
xref: uniprot P18499 293
organism: Strongylocentrotus purpuratus

PTHR24027:SF425
type: RelationshipXref
id: PTHR24027:SF425
db: PANTHER Family
relationship type: By Homology

PTHR24027:SF84
type: RelationshipXref
id: PTHR24027:SF84
db: PANTHER Family
relationship type: By Homology

PTHR24028:SF286
type: RelationshipXref
id: PTHR24028:SF286
db: PANTHER Family
relationship type: By Homology

PTHR24027:SF85
type: RelationshipXref
id: PTHR24027:SF85
db: PANTHER Family
relationship type: By Homology

PTHR24027:SF423
type: RelationshipXref
id: PTHR24027:SF423
db: PANTHER Family
relationship type: By Homology

PTHR24027:SF422
type: RelationshipXref
id: PTHR24027:SF422
db: PANTHER Family
relationship type: By Homology

Protocadherin beta-6
type: ProteinReference
xref: uniprot Q5DRC8 633
xref: PTHR24028:SF104
organism: Pan troglodytes

PTHR24028:SF281
type: RelationshipXref
id: PTHR24028:SF281
db: PANTHER Family
relationship type: By Homology

PTHR24027:SF80
type: RelationshipXref
id: PTHR24027:SF80
db: PANTHER Family
relationship type: By Homology

PTHR24027:SF81
type: RelationshipXref
id: PTHR24027:SF81
db: PANTHER Family
relationship type: By Homology

Protocadherin beta-11
type: ProteinReference
xref: uniprot Q5DRD8 639
xref: PTHR24028:SF286
organism: Pan troglodytes

Frizzled s27 sa21 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Frizzled
stoichiometric coefficient: 1.0

Frizzled-6
type: ProteinReference
xref: uniprot O60353 1021
xref: PTHR11309:SF75
organism: Homo sapiens

Protocadherin beta-12
type: ProteinReference
xref: PTHR24028:SF91
xref: uniprot Q5DRD7 638
organism: Pan troglodytes

uniprot A7RU31 180
type: UnificationXref
id: A7RU31
db: uniprot

PTHR24027:SF79
type: RelationshipXref
id: PTHR24027:SF79
db: PANTHER Family
relationship type: By Homology

PTHR24026:SF38
type: RelationshipXref
id: PTHR24026:SF38
db: PANTHER Family
relationship type: By Homology

Protocadherin beta-13
type: ProteinReference
xref: uniprot Q5DRD6 637
xref: PTHR24028:SF61
organism: Pan troglodytes

uniprot D4A7P5 442
type: UnificationXref
id: D4A7P5
db: uniprot

Frizzled-2
type: ProteinReference
xref: uniprot Q14332 1029
xref: PTHR11309:SF34
organism: Homo sapiens

Protocadherin beta-15
type: ProteinReference
xref: uniprot Q5DRD3 636
xref: PTHR24028:SF97
organism: Pan troglodytes

Protocadherin beta-2
type: ProteinReference
xref: uniprot Q5DRD2 635
xref: PTHR24028:SF281
organism: Pan troglodytes

Tyrosine-protein kinase
type: ProteinReference
xref: PTHR24418:SF53
xref: uniprot F7FWN9 150
organism: Macaca mulatta

Protocadherin beta-3
type: ProteinReference
xref: PTHR24028:SF118
xref: uniprot Q5DRD1 634
organism: Pan troglodytes

Uncharacterized protein
type: ProteinReference
xref: PTHR24028:SF254
xref: uniprot A0A1D5Q352 403
organism: Macaca mulatta

betacatenin s30 sa17 rs5
type: ModificationFeature
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=4.653633157668967
comment: MODIFICATION_RESIDUE_NAME=

Cadherin 10
type: ProteinReference
xref: uniprot E2R858 457
xref: PTHR24027:SF290
organism: Canis lupus familiaris

P120 s34 sa19 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: P120
stoichiometric coefficient: 1.0

PTHR24026:SF32
type: RelationshipXref
id: PTHR24026:SF32
db: PANTHER Family
relationship type: By Homology

uniprot P68138 334
type: UnificationXref
id: P68138
db: uniprot

Cadherin-18
type: ProteinReference
xref: PTHR24027:SF106
xref: uniprot Q13634 621
organism: Homo sapiens

PTHR24026:SF37
type: RelationshipXref
id: PTHR24026:SF37
db: PANTHER Family
relationship type: By Homology

TCF/LEF
type: Protein
entity reference: TCF/LEF
feature: COMPLEX PARTICIPANT BINDING FEATURE s29 sa23 1093
cellular location: nucleus
comment: SPECIES_TYPE=PROTEIN

uniprot Q5ZMQ2 360
type: UnificationXref
id: Q5ZMQ2
db: uniprot

PTHR24026:SF36
type: RelationshipXref
id: PTHR24026:SF36
db: PANTHER Family
relationship type: By Homology

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF387
xref: uniprot F6SCP4 249
organism: Ciona intestinalis

Cadherin 10
type: ProteinReference
xref: uniprot F6VET9 505
xref: PTHR24027:SF290
organism: Ornithorhynchus anatinus

ncbitaxon 7739 19
type: UnificationXref
id: 7739
db: ncbitaxon

uniprot F1N6L8 852
type: UnificationXref
id: F1N6L8
db: uniprot

uniprot D4ADD1 444
type: UnificationXref
id: D4ADD1
db: uniprot

Actin-related protein 2
type: ProteinReference
xref: uniprot A0A2I3TS83 169
xref: PTHR11937:SF409
organism: Pan troglodytes

uniprot A7MB62 179
type: UnificationXref
id: A7MB62
db: uniprot

uniprot Q91Y07 701
type: UnificationXref
id: Q91Y07
db: uniprot

betacatenin s30 sa17 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

alphacatenin s21 sa15 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: alphacatenin
stoichiometric coefficient: 1.0

uniprot Q6NV44 1038
type: UnificationXref
id: Q6NV44
db: uniprot

uniprot Q15303 140
type: UnificationXref
id: Q15303
db: uniprot

uniprot Q5DRC7 632
type: UnificationXref
id: Q5DRC7
db: uniprot

uniprot A0A2J8MVE2 423
type: UnificationXref
id: A0A2J8MVE2
db: uniprot

uniprot Q91VD8 685
type: UnificationXref
id: Q91VD8
db: uniprot

Frizzled-2
type: ProteinReference
xref: uniprot Q9JIP6 1049
xref: PTHR11309:SF34
organism: Mus musculus

S betacatenin s16 sa10 rs4
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY S
feature location: S betacatenin s16 sa10 rs4 S
comment: MODIFICATION_RESIDUE_NAME=S
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=1.6575346654708816

Protocadherin-20
type: ProteinReference
xref: uniprot Q8BIZ0 666
xref: PTHR24028:SF260
organism: Mus musculus

Protein Wnt-9a
type: ProteinReference
xref: PTHR12027:SF75
xref: uniprot O14904 896
organism: Homo sapiens

Protein Wnt-9b
type: ProteinReference
xref: PTHR12027:SF84
xref: uniprot O14905 897
organism: Homo sapiens

ncbitaxon 44689 281
type: UnificationXref
id: 44689
db: ncbitaxon

Actin-3
type: ProteinReference
xref: uniprot Q10AZ4 343
xref: PTHR11937:SF411
organism: Oryza sativa

uniprot Q9VVX3 1058
type: UnificationXref
id: Q9VVX3
db: uniprot

uniprot F1P8X5 487
type: UnificationXref
id: F1P8X5
db: uniprot

Frizzled-6
type: ProteinReference
xref: uniprot F6SV99 1000
xref: PTHR11309:SF75
organism: Macaca mulatta

ERBB3 protein
type: ProteinReference
xref: PTHR24416:SF88
xref: uniprot A6QR62 123
organism: Bos taurus

uniprot H2R198 575
type: UnificationXref
id: H2R198
db: uniprot

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF91
xref: uniprot F6SLU9 857
organism: Macaca mulatta

Uncharacterized protein
type: ProteinReference
xref: uniprot G3X6Y5 559
xref: PTHR24028:SF260
organism: Bos taurus

Protocadherin gamma-A12
type: ProteinReference
xref: PTHR24028:SF227
xref: uniprot O60330 581
organism: Homo sapiens

Fyn
type: ProteinReference
xref: P00464
standard name: Fyn tyrosine kinase protooncogene
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Fyn tyrosine kinase protooncogene Synonym: Syn Accession: P00464
comment: ENTITY_REFERENCE_ID_DESC=Cadherin signaling pathway.PROTEIN.GENERIC.Fyn
member entity reference: Tyrosine-protein kinase Fyn
member entity reference: Tyrosine-protein kinase
member entity reference: Tyrosine-protein kinase fynb
member entity reference: Tyrosine-protein kinase FRK
member entity reference: Tyrosine-protein kinase fyna

FZD3 isoform 1
type: ProteinReference
xref: uniprot A0A2J8N8E6 976
xref: PTHR11309:SF22
organism: Pan troglodytes

Protein Wnt
type: ProteinReference
xref: uniprot E1BKL2 842
xref: PTHR12027:SF92
organism: Bos taurus

uniprot F7EU36 263
type: UnificationXref
id: F7EU36
db: uniprot

uniprot P53492 302
type: UnificationXref
id: P53492
db: uniprot

Arabidopsis thaliana
type: BioSource
xref: ncbitaxon 3702 303

uniprot A9TYG3 198
type: UnificationXref
id: A9TYG3
db: uniprot

uniprot Q9Y6F9 969
type: UnificationXref
id: Q9Y6F9
db: uniprot

Actin beta
type: ProteinReference
xref: PTHR11937:SF192
xref: uniprot F6UDX9 254
organism: Ornithorhynchus anatinus

uniprot Q62799 143
type: UnificationXref
id: Q62799
db: uniprot

uniprot F7E6I8 533
type: UnificationXref
id: F7E6I8
db: uniprot

Receptor protein-tyrosine kinase
type: ProteinReference
xref: uniprot F7G3H1 127
xref: PTHR24416:SF90
organism: Macaca mulatta

uniprot F1NKC9 483
type: UnificationXref
id: F1NKC9
db: uniprot

Cadherin 11
type: ProteinReference
xref: PTHR24027:SF85
xref: uniprot F6UDX0 500
organism: Ornithorhynchus anatinus

uniprot Q9Y5F9 761
type: UnificationXref
id: Q9Y5F9
db: uniprot

uniprot Q9I9I2 961
type: UnificationXref
id: Q9I9I2
db: uniprot

uniprot F7FMS7 538
type: UnificationXref
id: F7FMS7
db: uniprot

Y654 betacatenin s119 a170 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y654
feature location: Y654 betacatenin s119 a170 rs1 Y654
modification type: phosphorylated residue
comment: MODIFICATION_RESIDUE_ANGLE=3.3479165476195107
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=Y654

uniprot P07828 280
type: UnificationXref
id: P07828
db: uniprot

Trichomonas vaginalis
type: BioSource
xref: ncbitaxon 5722 171

uniprot Q90762 681
type: UnificationXref
id: Q90762
db: uniprot

uniprot P15116 591
type: UnificationXref
id: P15116
db: uniprot

Danio rerio
type: BioSource
xref: ncbitaxon 7955 60

Frizzled class receptor 5
type: ProteinReference
xref: uniprot E2QVP7 985
xref: PTHR11309:SF136
organism: Canis lupus familiaris

S betacatenin s13 sa5 rs4
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY S
feature location: S betacatenin s13 sa5 rs4 S
comment: MODIFICATION_RESIDUE_NAME=S
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=1.6575346654708816

HETERODIMER_ASSOCIATION_LEFT__Cadherin-_P120-RIGHT__Complex__Cadherin_P120_-_r44
type: ComplexAssembly
spontaneous: true
conversion direction: LEFT_TO_RIGHT
xref: HETERODIMER ASSOCIATION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r44 1174
participant stoichiometry: PARTICIPANT STOICHIOMETRY r44 1173
participant stoichiometry: PARTICIPANT STOICHIOMETRY r44 1172
left: P120
left: Cadherin
interaction type: HETERODIMER_ASSOCIATION
right: Complex (Cadherin/P120)

Casein kinase 2 alpha 2
type: ProteinReference
xref: PTHR24054:SF34
xref: uniprot F6R511 27
organism: Monodelphis domestica

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF414
xref: uniprot A0A1D5Q7K7 165
organism: Macaca mulatta

Uncharacterized protein
type: ProteinReference
xref: uniprot F1MXP9 482
xref: PTHR24026:SF108
organism: Bos taurus

Tyrosine-protein phosphatase non-receptor type 1
type: ProteinReference
xref: uniprot P18031 789
organism: Homo sapiens

Protein mom-2
type: ProteinReference
xref: uniprot Q10459 936
xref: PTHR12027:SF3
organism: Caenorhabditis elegans

Protein Wnt
type: ProteinReference
xref: uniprot F7DI28 869
xref: PTHR12027:SF87
organism: Xenopus tropicalis

uniprot Q8WMU5 1045
type: UnificationXref
id: Q8WMU5
db: uniprot

Protein Wnt-10b
type: ProteinReference
xref: uniprot O00744 894
xref: PTHR12027:SF76
organism: Homo sapiens

uniprot F6WI86 510
type: UnificationXref
id: F6WI86
db: uniprot

Cadherin-14
type: ProteinReference
xref: PTHR24027:SF106
xref: uniprot F7FMS7 538
organism: Macaca mulatta

Tyrosine-protein kinase
type: ProteinReference
xref: uniprot A0A2I3SKP4 84
xref: PTHR24418:SF44
organism: Pan troglodytes

uniprot A8WS33 190
type: UnificationXref
id: A8WS33
db: uniprot

Complex (Cadherin/Cadherin/ betacatenin/alphacatenin/ F-actin)
type: Complex
component stoichiometry: alphacatenin s17 sa11 STOICHIOMETRY ID COMPLEX
component stoichiometry: Cadherin s14 sa8 STOICHIOMETRY ID COMPLEX
component stoichiometry: betacatenin s16 sa10 STOICHIOMETRY ID COMPLEX
component stoichiometry: F actin s18 sa12 STOICHIOMETRY ID COMPLEX
component: alphacatenin
component: betacatenin
component: Cadherin
component: F-actin
feature: COMPLEX BINDING FEATURE s72 a103 1132
feature: ACTIVE 162
feature: COMPLEX BINDING FEATURE s72 a103 1126
feature: COMPLEX BINDING FEATURE s72 a103 1130
feature: COMPLEX BINDING FEATURE s72 a103 1128
cellular location: cytoplasm

uniprot A8X402 822
type: UnificationXref
id: A8X402
db: uniprot

uniprot A8BV70 185
type: UnificationXref
id: A8BV70
db: uniprot

Frizzled class receptor 4
type: ProteinReference
xref: PTHR11309:SF23
xref: uniprot F7F2K2 1008
organism: Ornithorhynchus anatinus

ncbitaxon 9258 35
type: UnificationXref
id: 9258
db: ncbitaxon

Receptor tyrosine-protein kinase erbB-2
type: ProteinReference
xref: PTHR24416:SF137
xref: uniprot P06494 135
organism: Rattus norvegicus

uniprot F7D992 529
type: UnificationXref
id: F7D992
db: uniprot

Ustilago maydis
type: BioSource
xref: ncbitaxon 237631 164

Tyrosine-protein kinase
type: ProteinReference
xref: PTHR24418:SF90
xref: uniprot A0A1D5RAI3 1061
organism: Macaca mulatta

uniprot Q5DRF0 642
type: UnificationXref
id: Q5DRF0
db: uniprot

Protocadherin-16
type: ProteinReference
xref: uniprot E9PVD3 463
xref: PTHR24027:SF423
organism: Mus musculus

uniprot P48614 924
type: UnificationXref
id: P48614
db: uniprot

Non-muscle actin 6.2
type: ProteinReference
xref: uniprot B3RX77 207
xref: PTHR11937:SF387
organism: Trichoplax adhaerens

uniprot P35821 791
type: UnificationXref
id: P35821
db: uniprot

Frizzled class receptor 7
type: ProteinReference
xref: uniprot D4ACM8 984
xref: PTHR11309:SF31
organism: Rattus norvegicus

Protocadherin 19
type: ProteinReference
xref: uniprot A0A3Q1LJ38 428
xref: PTHR24028:SF40
organism: Bos taurus

FlaMIngo (Cadherin plus 7TM domain) homolog
type: ProteinReference
xref: PTHR24026:SF105
xref: uniprot G5EDK5 560
organism: Caenorhabditis elegans

uniprot Q24292 625
type: UnificationXref
id: Q24292
db: uniprot

Actin (Fragment)
type: ProteinReference
xref: uniprot A2HNG1 174
xref: PTHR11937:SF387
organism: Trichomonas vaginalis

PTHR11937:SF483
type: RelationshipXref
id: PTHR11937:SF483
db: PANTHER Family
relationship type: By Homology

uniprot Q08DJ5 619
type: UnificationXref
id: Q08DJ5
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F6WZD8 511
xref: PTHR24028:SF263
organism: Macaca mulatta

uniprot F6V5F4 1001
type: UnificationXref
id: F6V5F4
db: uniprot

Casein kinase II subunit beta
type: ProteinReference
xref: PTHR11740:SF0
xref: uniprot F6WVD0 33
organism: Xenopus tropicalis

uniprot F0ZK40 238
type: UnificationXref
id: F0ZK40
db: uniprot

HETERODIMER_ASSOCIATION_LEFT__Complex__Cadherin_betacatenin_-_Complex__alphacatenin_F_actin_-RIGHT__Complex__Cadherin_Cadherin__betacatenin_alphacatenin__F_actin_-_r17
type: ComplexAssembly
spontaneous: true
conversion direction: LEFT_TO_RIGHT
xref: HETERODIMER ASSOCIATION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r17 1162
participant stoichiometry: PARTICIPANT STOICHIOMETRY r17 1161
participant stoichiometry: PARTICIPANT STOICHIOMETRY r17 1163
left: Complex (alphacatenin/F-actin)
left: Complex (Cadherin/betacatenin)
interaction type: HETERODIMER_ASSOCIATION
right: Complex (Cadherin/Cadherin/ betacatenin/alphacatenin/ F-actin)

uniprot Q9VEU1 741
type: UnificationXref
id: Q9VEU1
db: uniprot

Protein Wnt
type: ProteinReference
xref: uniprot F6ZQ88 866
xref: PTHR12027:SF101
organism: Xenopus tropicalis

Cadherin-13
type: ProteinReference
xref: uniprot Q3B7N0 627
xref: PTHR24027:SF80
organism: Bos taurus

TRIGGER
type: Control
xref: TRIGGER
controlled: Endocytosis
controller: Complex (Cadherin/P120)

Actin-related protein 2
type: ProteinReference
xref: PTHR11937:SF37
xref: uniprot Q5BL41 353
organism: Xenopus tropicalis

uniprot F1LS01 469
type: UnificationXref
id: F1LS01
db: uniprot

Actin, cytoplasmic 1
type: ProteinReference
xref: PTHR11937:SF192
xref: uniprot O18840 275
organism: Canis lupus familiaris

uniprot E1BCK4 447
type: UnificationXref
id: E1BCK4
db: uniprot

uniprot A8XS95 192
type: UnificationXref
id: A8XS95
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F1MHH5 479
xref: PTHR24026:SF38
organism: Bos taurus

uniprot Q9VFX1 967
type: UnificationXref
id: Q9VFX1
db: uniprot

Protocadherin Fat 3
type: ProteinReference
xref: uniprot Q8TDW7 676
xref: PTHR24026:SF49
organism: Homo sapiens

FAT atypical cadherin 3
type: ProteinReference
xref: uniprot A0A2I3RVF5 413
xref: PTHR24026:SF49
organism: Pan troglodytes

uniprot A0A3Q1MPF5 816
type: UnificationXref
id: A0A3Q1MPF5
db: uniprot

alphacatenin
type: Protein
feature: COMPLEX PARTICIPANT BINDING FEATURE s21 sa15 1113
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

Predicted protein
type: ProteinReference
xref: uniprot A7RU31 180
xref: PTHR11937:SF387
organism: Nematostella vectensis

uniprot H2R0P7 574
type: UnificationXref
id: H2R0P7
db: uniprot

PTHR11309:SF81
type: RelationshipXref
id: PTHR11309:SF81
db: PANTHER Family
relationship type: By Homology

uniprot O24426 276
type: UnificationXref
id: O24426
db: uniprot

PTHR11309:SF86
type: RelationshipXref
id: PTHR11309:SF86
db: PANTHER Family
relationship type: By Homology

uniprot P68034 329
type: UnificationXref
id: P68034
db: uniprot

Cadherin-7
type: ProteinReference
xref: PTHR24027:SF91
xref: uniprot Q90763 682
organism: Gallus gallus

Cadherin-6
type: ProteinReference
xref: uniprot Q90762 681
xref: PTHR24027:SF322
organism: Gallus gallus

uniprot A7ETS6 177
type: UnificationXref
id: A7ETS6
db: uniprot

uniprot C3XYC3 211
type: UnificationXref
id: C3XYC3
db: uniprot

uniprot C3YKS6 221
type: UnificationXref
id: C3YKS6
db: uniprot

uniprot Q3B7N0 627
type: UnificationXref
id: Q3B7N0
db: uniprot

uniprot H2KNE6 267
type: UnificationXref
id: H2KNE6
db: uniprot

TCF/LEF
type: Protein
entity reference: TCF/LEF
cellular location: nucleus
comment: SPECIES_TYPE=PROTEIN

PTHR11937:SF468
type: RelationshipXref
id: PTHR11937:SF468
db: PANTHER Family
relationship type: By Homology

Actin-5C
type: ProteinReference
xref: uniprot P84185 339
xref: PTHR11937:SF387
organism: Anopheles gambiae

PTHR11937:SF469
type: RelationshipXref
id: PTHR11937:SF469
db: PANTHER Family
relationship type: By Homology

uniprot O77438 1024
type: UnificationXref
id: O77438
db: uniprot

PTHR11937:SF464
type: RelationshipXref
id: PTHR11937:SF464
db: PANTHER Family
relationship type: By Homology

Protein Wnt-16
type: ProteinReference
xref: PTHR12027:SF70
xref: uniprot Q9UBV4 966
organism: Homo sapiens

Protein Wnt
type: ProteinReference
xref: uniprot F1MHG3 848
xref: PTHR12027:SF94
organism: Bos taurus

uniprot F6VCS5 503
type: UnificationXref
id: F6VCS5
db: uniprot

Catenin beta-1
type: ProteinReference
xref: PTHR45976:SF4
xref: uniprot P35222 76
organism: Homo sapiens

Predicted protein
type: ProteinReference
xref: PTHR11937:SF473
xref: uniprot A7SEB1 184
organism: Nematostella vectensis

Rattus norvegicus
type: BioSource
xref: ncbitaxon 10116 15

PTHR11309:SF90
type: RelationshipXref
id: PTHR11309:SF90
db: PANTHER Family
relationship type: By Homology

ncbitaxon 9606 49
type: UnificationXref
id: 9606
db: ncbitaxon

uniprot H2R050 1015
type: UnificationXref
id: H2R050
db: uniprot

uniprot Q9QXQ7 963
type: UnificationXref
id: Q9QXQ7
db: uniprot

uniprot B6V8E6 69
type: UnificationXref
id: B6V8E6
db: uniprot

CATALYSIS
type: Catalysis
controlled: HETERODIMER_ASSOCIATION_LEFT__Cadherin-_Complex__betacatenin_alphacatenin__F_actin_-RIGHT__Complex__Cadherin_betacatenin__alphacatenin_F_actin_-_r42
controller: Complex (betacatenin/Tyrosine phosphatases/ P120)

uniprot F7F4W9 265
type: UnificationXref
id: F7F4W9
db: uniprot

AGAP006256-PA
type: ProteinReference
xref: PTHR24026:SF106
xref: uniprot Q7PPB2 652
organism: Anopheles gambiae

Cytoplasmatic actin
type: ProteinReference
xref: uniprot E9FZ00 234
xref: PTHR11937:SF387
organism: Daphnia pulex

PTHR11309:SF99
type: RelationshipXref
id: PTHR11309:SF99
db: PANTHER Family
relationship type: By Homology

PHYSICAL_STIMULATION
type: RelationshipTypeVocabulary

Cadherin 20
type: ProteinReference
xref: uniprot F7BBY2 521
xref: PTHR24027:SF84
organism: Xenopus tropicalis

uniprot A8WV58 821
type: UnificationXref
id: A8WV58
db: uniprot

PTHR11937:SF477
type: RelationshipXref
id: PTHR11937:SF477
db: PANTHER Family
relationship type: By Homology

Transcription factor 7-like 1
type: ProteinReference
xref: PTHR10373:SF25
xref: uniprot Q9Z1J1 119
organism: Mus musculus

ncbitaxon 367110 337
type: UnificationXref
id: 367110
db: ncbitaxon

uniprot Q75D00 372
type: UnificationXref
id: Q75D00
db: uniprot

PTHR11937:SF473
type: RelationshipXref
id: PTHR11937:SF473
db: PANTHER Family
relationship type: By Homology

Protein Wnt-11b-1
type: ProteinReference
xref: PTHR12027:SF34
xref: uniprot Q66II0 949
organism: Xenopus tropicalis

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF468
xref: uniprot C3YP58 222
organism: Branchiostoma floridae

PTHR11937:SF474
type: RelationshipXref
id: PTHR11937:SF474
db: PANTHER Family
relationship type: By Homology

S T Cadherin s14 sa8 rs2
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY S T
feature location: S T Cadherin s14 sa8 rs2 S T
modification type: phosphorylated residue
comment: MODIFICATION_RESIDUE_NAME=S/T
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=0.09

PTHR11937:SF471
type: RelationshipXref
id: PTHR11937:SF471
db: PANTHER Family
relationship type: By Homology

Predicted protein
type: ProteinReference
xref: uniprot A7SEA7 183
xref: PTHR11937:SF387
organism: Nematostella vectensis

uniprot P67871 55
type: UnificationXref
id: P67871
db: uniprot

PTHR11937:SF470
type: RelationshipXref
id: PTHR11937:SF470
db: PANTHER Family
relationship type: By Homology

Transcription factor 7-like 1-A
type: ProteinReference
xref: PTHR10373:SF25
xref: uniprot Q9YHE8 118
organism: Danio rerio

Protein Wnt
type: ProteinReference
xref: uniprot E2RH98 845
xref: PTHR12027:SF89
organism: Canis lupus familiaris

Lymphoid enhancer-binding factor 1
type: ProteinReference
xref: PTHR10373:SF11
xref: uniprot Q9UJU2 116
organism: Homo sapiens

uniprot F6R511 27
type: UnificationXref
id: F6R511
db: uniprot

uniprot Q91ZI0 703
type: UnificationXref
id: Q91ZI0
db: uniprot

ncbitaxon 1111708 615
type: UnificationXref
id: 1111708
db: ncbitaxon

uniprot A0A2I3RTC9 412
type: UnificationXref
id: A0A2I3RTC9
db: uniprot

uniprot W4Y0D3 82
type: UnificationXref
id: W4Y0D3
db: uniprot

uniprot F1MMW5 480
type: UnificationXref
id: F1MMW5
db: uniprot

uniprot O45815 277
type: UnificationXref
id: O45815
db: uniprot

uniprot H2QBL4 564
type: UnificationXref
id: H2QBL4
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR10373:SF11
xref: uniprot A0A3Q3B1W2 102
organism: Gallus gallus

uniprot Q91Y02 697
type: UnificationXref
id: Q91Y02
db: uniprot

uniprot P0DM42 286
type: UnificationXref
id: P0DM42
db: uniprot

Frizzled-1
type: ProteinReference
xref: PTHR11309:SF81
xref: uniprot O57328 1020
organism: Gallus gallus

Protocadherin alpha-2
type: ProteinReference
xref: PTHR24028:SF60
xref: uniprot Q5DRF0 642
organism: Pan troglodytes

PTHR24027:SF99
type: RelationshipXref
id: PTHR24027:SF99
db: PANTHER Family
relationship type: By Homology

uniprot Q5DWV1 643
type: UnificationXref
id: Q5DWV1
db: uniprot

Tyrosine-protein kinase
type: ProteinReference
xref: PTHR24418:SF227
xref: uniprot E1BNE0 155
organism: Bos taurus

uniprot P56703 931
type: UnificationXref
id: P56703
db: uniprot

uniprot A0A1D5Q7K7 165
type: UnificationXref
id: A0A1D5Q7K7
db: uniprot

Protocadherin Fat 3
type: ProteinReference
xref: uniprot Q8BNA6 668
xref: PTHR24026:SF49
organism: Mus musculus

Uncharacterized protein
type: ProteinReference
xref: uniprot F7HLC0 549
xref: PTHR24026:SF42
organism: Macaca mulatta

uniprot F1QBI2 993
type: UnificationXref
id: F1QBI2
db: uniprot

betacatenin
type: ProteinReference
xref: P00463
standard name: Beta-catenin
comment: ENTITY_REFERENCE_NOTES=Long Name: Beta-catenin Synonym: Synonym not specified Accession: P00463
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Cadherin signaling pathway.PROTEIN.GENERIC._beta_catenin
member entity reference: Catenin beta-1
member entity reference: Catenin, beta 2
member entity reference: CTNNB1 isoform 2
member entity reference: Catenin (Cadherin-associated protein), beta 1, 88kDa
member entity reference: Uncharacterized protein
member entity reference: Catenin beta 1

uniprot P09760 159
type: UnificationXref
id: P09760
db: uniprot

Frizzled class receptor 9b
type: ProteinReference
xref: uniprot B0S5E7 981
xref: PTHR11309:SF79
organism: Danio rerio

Tyrosine-protein kinase Fyn
type: ProteinReference
xref: uniprot Q05876 96
xref: PTHR24418:SF44
organism: Gallus gallus

FZD10 isoform 2
type: ProteinReference
xref: uniprot H2Q772 1012
xref: PTHR11309:SF86
organism: Pan troglodytes

Dictyostelium purpureum
type: BioSource
xref: ncbitaxon 5786 237

betacatenin s93 a132 rs5
type: ModificationFeature
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=4.653633157668967
comment: MODIFICATION_RESIDUE_NAME=

uniprot A0A1D5QLF4 405
type: UnificationXref
id: A0A1D5QLF4
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot C3ZMR2 226
organism: Branchiostoma floridae

uniprot Q61089 1034
type: UnificationXref
id: Q61089
db: uniprot

Cadherin 11, type 2, OB-cadherin (Osteoblast)
type: ProteinReference
xref: uniprot A2VDQ6 434
xref: PTHR24027:SF85
organism: Bos taurus

uniprot Q9QZH0 1053
type: UnificationXref
id: Q9QZH0
db: uniprot

uniprot D3ZRW5 835
type: UnificationXref
id: D3ZRW5
db: uniprot

uniprot A0A2I3RN05 410
type: UnificationXref
id: A0A2I3RN05
db: uniprot

Frizzled class receptor 5
type: ProteinReference
xref: uniprot B3DIG4 983
xref: PTHR11309:SF139
organism: Danio rerio

uniprot Q7ZVI7 379
type: UnificationXref
id: Q7ZVI7
db: uniprot

CATALYSIS
type: Catalysis
controlled: HETERODIMER_ASSOCIATION_LEFT__Complex__Cadherin_betacatenin_-_Complex__alphacatenin_F_actin_-RIGHT__Complex__Cadherin_Cadherin__betacatenin_alphacatenin__F_actin_-_r17
controller: Complex (betacatenin/Tyrosine phosphatases/ P120)

uniprot Q14517 622
type: UnificationXref
id: Q14517
db: uniprot

ncbitaxon 6238 13
type: UnificationXref
id: 6238
db: ncbitaxon

Tyrosine phosphatases s33 sa18 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Tyrosine phosphatases
stoichiometric coefficient: 1.0

cytoplasm
type: CellularLocationVocabulary
xref: GO GO:0005737 3

uniprot P55289 608
type: UnificationXref
id: P55289
db: uniprot

uniprot F6WVD0 33
type: UnificationXref
id: F6WVD0
db: uniprot

uniprot A0A2J8Q404 426
type: UnificationXref
id: A0A2J8Q404
db: uniprot

uniprot P30999 803
type: UnificationXref
id: P30999
db: uniprot

uniprot F6YS32 516
type: UnificationXref
id: F6YS32
db: uniprot

uniprot O14904 896
type: UnificationXref
id: O14904
db: uniprot

uniprot Q96JP9 705
type: UnificationXref
id: Q96JP9
db: uniprot

uniprot Q5DRE0 641
type: UnificationXref
id: Q5DRE0
db: uniprot

uniprot P41221 921
type: UnificationXref
id: P41221
db: uniprot

uniprot O18735 131
type: UnificationXref
id: O18735
db: uniprot

Cadherin-related hmr-1
type: ProteinReference
xref: uniprot Q967F4 704
xref: PTHR24026:SF102
organism: Caenorhabditis elegans

Protein CBG02167
type: ProteinReference
xref: uniprot A8WS37 191
xref: PTHR11937:SF470
organism: Caenorhabditis briggsae

Protocadherin 20
type: ProteinReference
xref: uniprot D4ADD1 444
xref: PTHR24028:SF260
organism: Rattus norvegicus

Protein Wnt
type: ProteinReference
xref: uniprot A0A0G2K6Q8 806
xref: PTHR12027:SF76
organism: Rattus norvegicus

uniprot Q91Y08 702
type: UnificationXref
id: Q91Y08
db: uniprot

uniprot C3XYC5 213
type: UnificationXref
id: C3XYC5
db: uniprot

PTHR24418:SF227
type: RelationshipXref
id: PTHR24418:SF227
db: PANTHER Family
relationship type: By Homology

Tyrosine-protein kinase Lyn
type: ProteinReference
xref: uniprot P07948 1072
organism: Homo sapiens

Tyrosine-protein kinase Yes
type: ProteinReference
xref: PTHR24418:SF90
xref: uniprot P07947 1071
organism: Homo sapiens

uniprot D4ACM8 984
type: UnificationXref
id: D4ACM8
db: uniprot

Protein Wnt-16
type: ProteinReference
xref: uniprot Q9QYS1 964
xref: PTHR12027:SF70
organism: Mus musculus

uniprot E1BF53 448
type: UnificationXref
id: E1BF53
db: uniprot

Protocadherin 8, gene 2
type: ProteinReference
xref: PTHR24028:SF46
xref: uniprot F6VDD4 504
organism: Xenopus tropicalis

Protein CBG02161
type: ProteinReference
xref: uniprot A8WS32 189
xref: PTHR11937:SF471
organism: Caenorhabditis briggsae

uniprot P63269 325
type: UnificationXref
id: P63269
db: uniprot

Protein CBG02162
type: ProteinReference
xref: uniprot A8WS33 190
xref: PTHR11937:SF471
organism: Caenorhabditis briggsae

Y142 betacatenin s94 a133 rs2
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y142
feature location: Y142 betacatenin s94 a133 rs2 Y142
comment: MODIFICATION_RESIDUE_NAME=Y142
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=2.893781136851091

Uncharacterized protein
type: ProteinReference
xref: uniprot C3ZHN2 224
xref: PTHR11937:SF446
organism: Branchiostoma floridae

Protocadherin beta 9
type: ProteinReference
xref: uniprot E9Q5G2 465
xref: PTHR24028:SF239
organism: Mus musculus

PTHR24416:SF88
type: RelationshipXref
id: PTHR24416:SF88
db: PANTHER Family
relationship type: By Homology

Catenin, beta 2
type: ProteinReference
xref: PTHR45976:SF4
xref: uniprot E7FC99 70
organism: Danio rerio

PARTICIPANT STOICHIOMETRY r43 1179
type: Stoichiometry
physical entity: Complex (betacatenin/alphacatenin/ F-actin)
stoichiometric coefficient: 1.0

Uncharacterized protein
type: ProteinReference
xref: uniprot C3ZHN4 225
xref: PTHR11937:SF446
organism: Branchiostoma floridae

STATE_TRANSITION_LEFT__betacatenin-RIGHT__betacatenin-_r25
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r25 1184
participant stoichiometry: PARTICIPANT STOICHIOMETRY r25 1183
left: betacatenin
interaction type: STATE_TRANSITION
right: betacatenin

uniprot P04412 133
type: UnificationXref
id: P04412
db: uniprot

betacatenin
type: Protein
entity reference: betacatenin
feature: S betacatenin s112 a160 rs4
feature: betacatenin s112 a160 rs5
feature: Y654 betacatenin s112 a160 rs1
feature: Y142 betacatenin s112 a160 rs2
feature: T112 betacatenin s112 a160 rs3
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

uniprot P60712 313
type: UnificationXref
id: P60712
db: uniprot

uniprot A0A0D1DMT3 163
type: UnificationXref
id: A0A0D1DMT3
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F6RFW8 248
xref: PTHR11937:SF192
organism: Monodelphis domestica

PARTICIPANT STOICHIOMETRY r43 1178
type: Stoichiometry
physical entity: Cadherin
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r43 1177
type: Stoichiometry
physical entity: Complex (Cadherin/betacatenin/ alphacatenin/F-actin)
stoichiometric coefficient: 1.0

uniprot A0A1D5PEJ9 973
type: UnificationXref
id: A0A1D5PEJ9
db: uniprot

Cadherin EGF LAG seven-pass G-type receptor 2
type: ProteinReference
xref: uniprot E2R4F0 455
xref: PTHR24026:SF32
organism: Canis lupus familiaris

uniprot F6RPG1 998
type: UnificationXref
id: F6RPG1
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR24027:SF99
xref: uniprot F7GUW1 545
organism: Macaca mulatta

Yarrowia lipolytica
type: BioSource
xref: ncbitaxon 284591 390

uniprot P68139 335
type: UnificationXref
id: P68139
db: uniprot

uniprot F7CX56 528
type: UnificationXref
id: F7CX56
db: uniprot

STATE_TRANSITION_LEFT__betacatenin-RIGHT__betacatenin-_r39
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r39 1154
participant stoichiometry: PARTICIPANT STOICHIOMETRY r39 1155
left: betacatenin
interaction type: STATE_TRANSITION
right: betacatenin

Frizzled-5
type: ProteinReference
xref: uniprot Q8CHL0 1042
xref: PTHR11309:SF136
organism: Rattus norvegicus

uniprot Q27886 938
type: UnificationXref
id: Q27886
db: uniprot

PTHR11309:SF34
type: RelationshipXref
id: PTHR11309:SF34
db: PANTHER Family
relationship type: By Homology

PTHR12027:SF7
type: RelationshipXref
id: PTHR12027:SF7
db: PANTHER Family
relationship type: By Homology

uniprot P07829 282
type: UnificationXref
id: P07829
db: uniprot

Frizzled-1
type: ProteinReference
xref: PTHR11309:SF81
xref: uniprot Q9UP38 1057
organism: Homo sapiens

uniprot F7E738 870
type: UnificationXref
id: F7E738
db: uniprot

Actin, alpha cardiac muscle 1
type: ProteinReference
xref: PTHR11937:SF176
xref: uniprot Q3ZC07 347
organism: Bos taurus

PTHR12027:SF3
type: RelationshipXref
id: PTHR12027:SF3
db: PANTHER Family
relationship type: By Homology

uniprot Q9Y5E7 751
type: UnificationXref
id: Q9Y5E7
db: uniprot

Catenin (Cadherin associated protein), delta 1 (Predicted), isoform CRA_a
type: ProteinReference
xref: uniprot D3ZZZ9 795
organism: Rattus norvegicus

uniprot H2R591 1017
type: UnificationXref
id: H2R591
db: uniprot

Protein Wnt-3a
type: ProteinReference
xref: PTHR12027:SF88
xref: uniprot P27467 914
organism: Mus musculus

PTHR11309:SF31
type: RelationshipXref
id: PTHR11309:SF31
db: PANTHER Family
relationship type: By Homology

uniprot P68136 333
type: UnificationXref
id: P68136
db: uniprot

Frizzled class receptor 9
type: ProteinReference
xref: PTHR11309:SF79
xref: uniprot E2RAF3 987
organism: Canis lupus familiaris

Glycogen synthase kinase-3 beta
type: ProteinReference
xref: uniprot P49841 1087
xref: PTHR24057:SF8
organism: Homo sapiens

uniprot F6QL95 996
type: UnificationXref
id: F6QL95
db: uniprot

uniprot A2HNG1 174
type: UnificationXref
id: A2HNG1
db: uniprot

uniprot Q8QFM3 1044
type: UnificationXref
id: Q8QFM3
db: uniprot

Y Cadherin s19 sa13 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y
feature location: Y Cadherin s19 sa13 rs1 Y
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=Y
comment: MODIFICATION_RESIDUE_ANGLE=3.14

T112 betacatenin s20 sa14 rs3
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY T112
feature location: T112 betacatenin s20 sa14 rs3 T112
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=T112
comment: MODIFICATION_RESIDUE_ANGLE=-0.0

PTHR11309:SF22
type: RelationshipXref
id: PTHR11309:SF22
db: PANTHER Family
relationship type: By Homology

PTHR11309:SF23
type: RelationshipXref
id: PTHR11309:SF23
db: PANTHER Family
relationship type: By Homology

uniprot Q8TDW7 676
type: UnificationXref
id: Q8TDW7
db: uniprot

Tyrosine-protein kinase fynb
type: ProteinReference
xref: uniprot F1RDG9 87
xref: PTHR24418:SF44
organism: Danio rerio

uniprot E2RBB8 1064
type: UnificationXref
id: E2RBB8
db: uniprot

uniprot Q967F4 704
type: UnificationXref
id: Q967F4
db: uniprot

betacatenin s3 a16 rs5
type: ModificationFeature
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=4.653633157668967
comment: MODIFICATION_RESIDUE_NAME=

Cadherin
type: Protein
entity reference: Cadherin
feature: Y Cadherin s19 sa13 rs1
feature: S T Cadherin s19 sa13 rs2
feature: COMPLEX PARTICIPANT BINDING FEATURE s19 sa13 1109
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

uniprot E2RB53 1082
type: UnificationXref
id: E2RB53
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF414
xref: uniprot F7DIB7 261
organism: Monodelphis domestica

uniprot P73089 614
type: UnificationXref
id: P73089
db: uniprot

uniprot A0A1L1SQU7 407
type: UnificationXref
id: A0A1L1SQU7
db: uniprot

PTHR11937:SF176
type: RelationshipXref
id: PTHR11937:SF176
db: PANTHER Family
relationship type: By Homology

uniprot H2QKP9 565
type: UnificationXref
id: H2QKP9
db: uniprot

uniprot A0A2A6CRA8 167
type: UnificationXref
id: A0A2A6CRA8
db: uniprot

uniprot K7CVS9 37
type: UnificationXref
id: K7CVS9
db: uniprot

uniprot Q9R100 727
type: UnificationXref
id: Q9R100
db: uniprot

uniprot E1BJ11 450
type: UnificationXref
id: E1BJ11
db: uniprot

uniprot F7GRQ8 544
type: UnificationXref
id: F7GRQ8
db: uniprot

uniprot C3ZTX6 227
type: UnificationXref
id: C3ZTX6
db: uniprot

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF89
xref: uniprot D3ZRW5 835
organism: Rattus norvegicus

Dachsous cadherin-related 1
type: ProteinReference
xref: PTHR24027:SF423
xref: uniprot E1B969 445
organism: Bos taurus

uniprot H2QRN3 571
type: UnificationXref
id: H2QRN3
db: uniprot

actin, muscle
type: ProteinReference
xref: uniprot F6SDC9 250
organism: Ciona intestinalis

uniprot F1N5R1 851
type: UnificationXref
id: F1N5R1
db: uniprot

Tyrosine-protein kinase Fer
type: ProteinReference
xref: uniprot P16591 160
xref: PTHR24418:SF227
organism: Homo sapiens

uniprot F1MA46 475
type: UnificationXref
id: F1MA46
db: uniprot

uniprot F6X6I5 1067
type: UnificationXref
id: F6X6I5
db: uniprot

PTHR11937:SF168
type: RelationshipXref
id: PTHR11937:SF168
db: PANTHER Family
relationship type: By Homology

uniprot P28548 52
type: UnificationXref
id: P28548
db: uniprot

uniprot F7CIV4 260
type: UnificationXref
id: F7CIV4
db: uniprot

PTHR11309:SF47
type: RelationshipXref
id: PTHR11309:SF47
db: PANTHER Family
relationship type: By Homology

Cadherin 22
type: ProteinReference
xref: PTHR24027:SF311
xref: uniprot E2RJN9 460
organism: Canis lupus familiaris

uniprot F1MC84 477
type: UnificationXref
id: F1MC84
db: uniprot

S betacatenin s94 a133 rs4
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY S
feature location: S betacatenin s94 a133 rs4 S
modification type: phosphorylated residue
comment: MODIFICATION_RESIDUE_NAME=S
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=1.6575346654708816

Protein Wnt-10a
type: ProteinReference
xref: uniprot P43446 922
xref: PTHR12027:SF89
organism: Danio rerio

uniprot Q6GL20 1037
type: UnificationXref
id: Q6GL20
db: uniprot

Cadherin 24
type: ProteinReference
xref: uniprot A0A2I3SIV3 416
xref: PTHR24027:SF272
organism: Pan troglodytes

PTHR11937:SF162
type: RelationshipXref
id: PTHR11937:SF162
db: PANTHER Family
relationship type: By Homology

PTHR24416:SF90
type: RelationshipXref
id: PTHR24416:SF90
db: PANTHER Family
relationship type: By Homology

PTHR24416:SF91
type: RelationshipXref
id: PTHR24416:SF91
db: PANTHER Family
relationship type: By Homology

uniprot E2QX93 454
type: UnificationXref
id: E2QX93
db: uniprot

F actin s23 sa16 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: F-actin
stoichiometric coefficient: 1.0

uniprot E2RAF3 987
type: UnificationXref
id: E2RAF3
db: uniprot

betacatenin s28 sa22 rs5
type: ModificationFeature
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=4.653633157668967
comment: MODIFICATION_RESIDUE_NAME=

CATALYSIS
type: Catalysis
controlled: DISSOCIATION_LEFT__Complex__Cadherin_betacatenin__alphacatenin_F_actin_-RIGHT__Cadherin-_Complex__betacatenin_alphacatenin__F_actin_-_r43
controller: Fer

betacatenin s16 sa10 rs5
type: ModificationFeature
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=4.653633157668967
comment: MODIFICATION_RESIDUE_NAME=

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__betacatenin-RIGHT__betacatenin-_r25
controller: GSK3beta

Zgc:86598
type: ProteinReference
xref: uniprot Q6IQV0 59
xref: PTHR24054:SF28
organism: Danio rerio

Protocadherin beta 10
type: ProteinReference
xref: uniprot Q91VE5 686
xref: PTHR24028:SF90
organism: Mus musculus

Frizzled 8a protein
type: ProteinReference
xref: PTHR11309:SF140
xref: uniprot Q9YI00 1060
organism: Danio rerio

ncbitaxon 284591 390
type: UnificationXref
id: 284591
db: ncbitaxon

Complex (betacatenin/TCF/LEF)
type: Complex
component stoichiometry: TCF LEF s29 sa23 STOICHIOMETRY ID COMPLEX
component stoichiometry: betacatenin s28 sa22 STOICHIOMETRY ID COMPLEX
component: TCF/LEF
component: betacatenin
feature: ACTIVE 162
feature: COMPLEX BINDING FEATURE s108 a153 1092
feature: COMPLEX BINDING FEATURE s108 a153 1090
cellular location: nucleus

PTHR11309:SF75
type: RelationshipXref
id: PTHR11309:SF75
db: PANTHER Family
relationship type: By Homology

uniprot Q90275 680
type: UnificationXref
id: Q90275
db: uniprot

PTHR11937:SF154
type: RelationshipXref
id: PTHR11937:SF154
db: PANTHER Family
relationship type: By Homology

uniprot F7HEW6 876
type: UnificationXref
id: F7HEW6
db: uniprot

PTHR11309:SF79
type: RelationshipXref
id: PTHR11309:SF79
db: PANTHER Family
relationship type: By Homology

PTHR11937:SF150
type: RelationshipXref
id: PTHR11937:SF150
db: PANTHER Family
relationship type: By Homology

uniprot Q91Y01 696
type: UnificationXref
id: Q91Y01
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot E9GCV0 22
xref: PTHR24054:SF0
organism: Daphnia pulex

uniprot F7A659 1003
type: UnificationXref
id: F7A659
db: uniprot

uniprot F7CBX9 527
type: UnificationXref
id: F7CBX9
db: uniprot

Cadherin-6
type: ProteinReference
xref: PTHR24027:SF322
xref: uniprot Q3SWX5 628
organism: Bos taurus

MCG141290
type: ProteinReference
xref: uniprot Q91VD8 685
xref: PTHR24028:SF71
organism: Mus musculus

uniprot E2R790 456
type: UnificationXref
id: E2R790
db: uniprot

Cadherin-10 preproprotein
type: ProteinReference
xref: PTHR24027:SF290
xref: uniprot F7DRD8 531
organism: Macaca mulatta

uniprot O14905 897
type: UnificationXref
id: O14905
db: uniprot

Y Fer s7 a94 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y
feature location: Y Fer s7 a94 rs1 Y
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=Y
comment: MODIFICATION_RESIDUE_ANGLE=3.141592653589793

Casein kinase II
type: ProteinReference
xref: P00462
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Cadherin signaling pathway.PROTEIN.GENERIC.Casein kinase II
comment: ENTITY_REFERENCE_NOTES=Long Name: Casein kinase II Synonym: Synonym not specified Accession: P00462
member entity reference: Casein kinase II subunit alpha'
member entity reference: Casein kinase 2 alpha 2
member entity reference: CSNK2A1 isoform 3
member entity reference: Casein kinase 2, alpha prime polypeptide a
member entity reference: Casein kinase II subunit alpha
member entity reference: Protein CBR-KIN-3
member entity reference: Casein kinase 2 beta
member entity reference: Uncharacterized protein
member entity reference: Casein kinase II subunit beta
member entity reference: CSNK2A2 isoform 1
member entity reference: Zgc:86598
member entity reference: AGAP005569-PA
member entity reference: Casein kinase II subunit alpha 3
member entity reference: Casein kinase 2 alpha subunit
member entity reference: Casein kinase II subunit beta'

uniprot Q6EWH2 98
type: UnificationXref
id: Q6EWH2
db: uniprot

PTHR11937:SF149
type: RelationshipXref
id: PTHR11937:SF149
db: PANTHER Family
relationship type: By Homology

Protocadherin 9
type: ProteinReference
xref: uniprot F1P7Y5 485
xref: PTHR24028:SF248
organism: Canis lupus familiaris

uniprot Q5F226 645
type: UnificationXref
id: Q5F226
db: uniprot

AGAP007207-PA
type: ProteinReference
xref: uniprot A0NBC9 433
xref: PTHR24026:SF108
organism: Anopheles gambiae

Protein Wnt-11
type: ProteinReference
xref: uniprot O96014 901
xref: PTHR12027:SF7
organism: Homo sapiens

uniprot P49339 927
type: UnificationXref
id: P49339
db: uniprot

uniprot F1QK98 853
type: UnificationXref
id: F1QK98
db: uniprot

uniprot Q8QGH3 672
type: UnificationXref
id: Q8QGH3
db: uniprot

S betacatenin s30 sa17 rs4
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY S
feature location: S betacatenin s30 sa17 rs4 S
comment: MODIFICATION_RESIDUE_NAME=S
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=1.6575346654708816

uniprot P61161 315
type: UnificationXref
id: P61161
db: uniprot

F-actin
type: Protein
entity reference: F-actin
feature: COMPLEX PARTICIPANT BINDING FEATURE s18 sa12 1133
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

uniprot A7SEA7 183
type: UnificationXref
id: A7SEA7
db: uniprot

uniprot Q60737 58
type: UnificationXref
id: Q60737
db: uniprot

uniprot Q64527 948
type: UnificationXref
id: Q64527
db: uniprot

uniprot P28465 916
type: UnificationXref
id: P28465
db: uniprot

uniprot Q02248 78
type: UnificationXref
id: Q02248
db: uniprot

uniprot F6ZBJ4 107
type: UnificationXref
id: F6ZBJ4
db: uniprot

uniprot Q498S8 1030
type: UnificationXref
id: Q498S8
db: uniprot

uniprot P68134 332
type: UnificationXref
id: P68134
db: uniprot

Cadherin 7
type: ProteinReference
xref: uniprot E1BF53 448
xref: PTHR24027:SF91
organism: Bos taurus

uniprot F7GVJ2 546
type: UnificationXref
id: F7GVJ2
db: uniprot

PARTICIPANT STOICHIOMETRY r22 1141
type: Stoichiometry
physical entity: Cadherin
stoichiometric coefficient: 1.0

uniprot F1P476 240
type: UnificationXref
id: F1P476
db: uniprot

PARTICIPANT STOICHIOMETRY r22 1142
type: Stoichiometry
physical entity: Complex (Cadherin/betacatenin/ alphacatenin/F-actin)
stoichiometric coefficient: 1.0

uniprot A8WS37 191
type: UnificationXref
id: A8WS37
db: uniprot

eco ECO:0000305 172
type: UnificationXref
id: ECO:0000305
db: eco

uniprot G3V6K6 129
type: UnificationXref
id: G3V6K6
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR24028:SF253
xref: uniprot F7HN04 550
organism: Macaca mulatta

PARTICIPANT STOICHIOMETRY r22 1143
type: Stoichiometry
physical entity: Complex (Cadherin/Cadherin/ betacatenin/alphacatenin/ F-actin)
stoichiometric coefficient: 1.0

Cadherin-4
type: ProteinReference
xref: uniprot Q19319 624
xref: PTHR24025:SF23
organism: Caenorhabditis elegans

Cadherin-6
type: ProteinReference
xref: uniprot P97326 617
xref: PTHR24027:SF322
organism: Mus musculus

Uncharacterized protein
type: ProteinReference
xref: uniprot W4Y0D3 82
organism: Strongylocentrotus purpuratus

uniprot Q9Y5H4 772
type: UnificationXref
id: Q9Y5H4
db: uniprot

uniprot P84185 339
type: UnificationXref
id: P84185
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F1P802 486
xref: PTHR24028:SF260
organism: Canis lupus familiaris

Casein kinase II subunit beta
type: ProteinReference
xref: PTHR11740:SF0
xref: uniprot P28548 52
organism: Caenorhabditis elegans

Y Cadherin s24 sa24 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y
feature location: Y Cadherin s24 sa24 rs1 Y
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=Y
comment: MODIFICATION_RESIDUE_ANGLE=3.14

uniprot P0DM41 285
type: UnificationXref
id: P0DM41
db: uniprot

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF91
xref: uniprot C3YYJ8 827
organism: Branchiostoma floridae

P120
type: Protein
entity reference: P120
feature: P120 s34 sa19 rs1
feature: COMPLEX PARTICIPANT BINDING FEATURE s34 sa19 1099
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

Ornithorhynchus anatinus
type: BioSource
xref: ncbitaxon 9258 35

Casein kinase II subunit alpha
type: ProteinReference
xref: uniprot Q60737 58
xref: PTHR24054:SF16
organism: Mus musculus

Actin, alpha cardiac muscle 1
type: ProteinReference
xref: PTHR11937:SF176
xref: uniprot P68033 328
organism: Mus musculus

S betacatenin s3 a16 rs4
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY S
feature location: S betacatenin s3 a16 rs4 S
comment: MODIFICATION_RESIDUE_NAME=S
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=1.6575346654708816

Actin, alpha cardiac muscle 1
type: ProteinReference
xref: PTHR11937:SF176
xref: uniprot P68032 327
organism: Homo sapiens

uniprot F7H7P8 875
type: UnificationXref
id: F7H7P8
db: uniprot

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF88
xref: uniprot F1QK98 853
organism: Danio rerio

uniprot P02574 279
type: UnificationXref
id: P02574
db: uniprot

uniprot Q967X2 68
type: UnificationXref
id: Q967X2
db: uniprot

ncbitaxon 10116 15
type: UnificationXref
id: 10116
db: ncbitaxon

uniprot Q0VCX4 79
type: UnificationXref
id: Q0VCX4
db: uniprot

Actin, alpha cardiac muscle 1
type: ProteinReference
xref: PTHR11937:SF176
xref: uniprot P68035 330
organism: Rattus norvegicus

uniprot Q9DEB8 957
type: UnificationXref
id: Q9DEB8
db: uniprot

uniprot F6WHM2 861
type: UnificationXref
id: F6WHM2
db: uniprot

Actin, alpha cardiac muscle 1
type: ProteinReference
xref: PTHR11937:SF176
xref: uniprot P68034 329
organism: Gallus gallus

uniprot Q08174 618
type: UnificationXref
id: Q08174
db: uniprot

Cadherin-24
type: ProteinReference
xref: uniprot Q86UP0 665
xref: PTHR24027:SF272
organism: Homo sapiens

uniprot F6TCQ4 859
type: UnificationXref
id: F6TCQ4
db: uniprot

uniprot Q5BL72 1031
type: UnificationXref
id: Q5BL72
db: uniprot

PTHR11937:SF193
type: RelationshipXref
id: PTHR11937:SF193
db: PANTHER Family
relationship type: By Homology

PTHR11937:SF192
type: RelationshipXref
id: PTHR11937:SF192
db: PANTHER Family
relationship type: By Homology

uniprot Q8BIZ0 666
type: UnificationXref
id: Q8BIZ0
db: uniprot

CTNNB1 isoform 2
type: ProteinReference
xref: PTHR45976:SF4
xref: uniprot H2R2U1 75
organism: Pan troglodytes

TRIGGER
type: Control
xref: TRIGGER
controlled: Cell Adhesion
controller: Complex (Cadherin/Cadherin/ betacatenin/alphacatenin/ F-actin)

uniprot Q9QYS1 964
type: UnificationXref
id: Q9QYS1
db: uniprot

uniprot F6VCI6 32
type: UnificationXref
id: F6VCI6
db: uniprot

PTHR24054:SF16
type: RelationshipXref
id: PTHR24054:SF16
db: PANTHER Family
relationship type: By Homology

Cadherin 11
type: ProteinReference
xref: PTHR24027:SF85
xref: uniprot F1MAH6 476
organism: Rattus norvegicus

HETERODIMER_ASSOCIATION_LEFT__Cadherin-_Complex__Cadherin_betacatenin__alphacatenin_F_actin_-RIGHT__Complex__Cadherin_Cadherin__betacatenin_alphacatenin__F_actin_-_r22
type: ComplexAssembly
spontaneous: true
conversion direction: LEFT_TO_RIGHT
xref: HETERODIMER ASSOCIATION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r22 1143
participant stoichiometry: PARTICIPANT STOICHIOMETRY r22 1141
participant stoichiometry: PARTICIPANT STOICHIOMETRY r22 1142
left: Complex (Cadherin/betacatenin/ alphacatenin/F-actin)
left: Cadherin
interaction type: HETERODIMER_ASSOCIATION
right: Complex (Cadherin/Cadherin/ betacatenin/alphacatenin/ F-actin)

uniprot O70283 899
type: UnificationXref
id: O70283
db: uniprot

Protocadherin-like wing polarity protein stan
type: ProteinReference
xref: PTHR24026:SF51
xref: uniprot Q9V5N8 739
organism: Drosophila melanogaster

uniprot Q6P640 368
type: UnificationXref
id: Q6P640
db: uniprot

uniprot Q3L254 944
type: UnificationXref
id: Q3L254
db: uniprot

uniprot A0A1D5R803 810
type: UnificationXref
id: A0A1D5R803
db: uniprot

AGAP004850-PA
type: ProteinReference
xref: uniprot Q7PPU8 653
xref: PTHR24026:SF51
organism: Anopheles gambiae

PTHR11937:SF184
type: RelationshipXref
id: PTHR11937:SF184
db: PANTHER Family
relationship type: By Homology

Cadherin-4
type: ProteinReference
xref: uniprot P39038 599
xref: PTHR24027:SF81
organism: Mus musculus

uniprot C3XYC7 215
type: UnificationXref
id: C3XYC7
db: uniprot

Canis lupus familiaris
type: BioSource
xref: ncbitaxon 9615 21

uniprot Q12864 620
type: UnificationXref
id: Q12864
db: uniprot

Cadherin 11
type: ProteinReference
xref: uniprot A0A2I3TJM5 419
xref: PTHR24027:SF85
organism: Pan troglodytes

uniprot F6QAX3 494
type: UnificationXref
id: F6QAX3
db: uniprot

Cell Adhesion
type: Pathway

uniprot Q7PM77 950
type: UnificationXref
id: Q7PM77
db: uniprot

uniprot F7DRD8 531
type: UnificationXref
id: F7DRD8
db: uniprot

uniprot A0A1D5PYV2 401
type: UnificationXref
id: A0A1D5PYV2
db: uniprot

uniprot F1M7D0 473
type: UnificationXref
id: F1M7D0
db: uniprot

Endocytosis
type: Pathway

Frizzled class receptor 8
type: ProteinReference
xref: uniprot H2R050 1015
xref: PTHR11309:SF90
organism: Pan troglodytes

Protocadherin-18
type: ProteinReference
xref: uniprot Q9HCL0 717
xref: PTHR24028:SF9
organism: Homo sapiens

Frizzled class receptor 2
type: ProteinReference
xref: PTHR11309:SF34
xref: uniprot F7DIA9 1005
organism: Ornithorhynchus anatinus

Frizzled-8
type: ProteinReference
xref: PTHR11309:SF90
xref: uniprot Q498S8 1030
organism: Rattus norvegicus

Tyrosine-protein kinase
type: ProteinReference
xref: PTHR24418:SF53
xref: uniprot F6WR53 149
organism: Monodelphis domestica

uniprot A8WV10 820
type: UnificationXref
id: A8WV10
db: uniprot

uniprot A0A2I3RVF5 413
type: UnificationXref
id: A0A2I3RVF5
db: uniprot

Os12g0163700 protein
type: ProteinReference
xref: uniprot Q0IPW3 342
xref: PTHR11937:SF474
organism: Oryza sativa

uniprot P55281 601
type: UnificationXref
id: P55281
db: uniprot

uniprot P34889 919
type: UnificationXref
id: P34889
db: uniprot

Receptor protein-tyrosine kinase (Fragment)
type: ProteinReference
xref: PTHR24416:SF566
xref: uniprot Q7PPN5 145
organism: Anopheles gambiae

uniprot F6UY89 502
type: UnificationXref
id: F6UY89
db: uniprot

uniprot H9EPM1 1085
type: UnificationXref
id: H9EPM1
db: uniprot

Protocadherin 11 X-linked (Predicted)
type: ProteinReference
xref: PTHR24028:SF254
xref: uniprot D4A497 441
organism: Rattus norvegicus

Cadherin related 23
type: ProteinReference
xref: uniprot A0A2I3RE49 408
xref: PTHR24027:SF425
organism: Pan troglodytes

Tyrosine-protein kinase Fyn
type: ProteinReference
xref: PTHR24418:SF44
xref: uniprot Q62844 97
organism: Rattus norvegicus

T112 betacatenin s119 a170 rs3
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY T112
feature location: T112 betacatenin s119 a170 rs3 T112
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=T112
comment: MODIFICATION_RESIDUE_ANGLE=-0.0

uniprot H2QBE4 563
type: UnificationXref
id: H2QBE4
db: uniprot

Protein CBR-ACT-2
type: ProteinReference
xref: uniprot A8Y4Q9 193
xref: PTHR11937:SF471
organism: Caenorhabditis briggsae

uniprot Q9NRJ7 720
type: UnificationXref
id: Q9NRJ7
db: uniprot

Y Cadherin s14 sa8 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y
feature location: Y Cadherin s14 sa8 rs1 Y
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=Y
comment: MODIFICATION_RESIDUE_ANGLE=3.14

Uncharacterized protein
type: ProteinReference
xref: uniprot E1BJ11 450
xref: PTHR24025:SF17
organism: Bos taurus

uniprot P06241 93
type: UnificationXref
id: P06241
db: uniprot

uniprot Q10459 936
type: UnificationXref
id: Q10459
db: uniprot

Transcription factor 7-like 1
type: ProteinReference
xref: PTHR10373:SF25
xref: uniprot Q9HCS4 113
organism: Homo sapiens

uniprot Q9Y5G8 767
type: UnificationXref
id: Q9Y5G8
db: uniprot

uniprot E2RJN9 460
type: UnificationXref
id: E2RJN9
db: uniprot

uniprot F6S8L5 89
type: UnificationXref
id: F6S8L5
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F6ZZG9 257
xref: PTHR11937:SF168
organism: Monodelphis domestica

betacatenin s20 sa14 rs5
type: ModificationFeature
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=4.653633157668967
comment: MODIFICATION_RESIDUE_NAME=

Cadherin-89D
type: ProteinReference
xref: uniprot Q9VEU1 741
xref: PTHR24026:SF89
organism: Drosophila melanogaster

Transcription factor 7 like 1
type: ProteinReference
xref: PTHR10373:SF25
xref: uniprot F7AIP6 108
organism: Monodelphis domestica

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF82
xref: uniprot B0LK22 823
organism: Danio rerio

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF86
xref: uniprot Q2IBD1 940
organism: Rattus norvegicus

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF72
xref: uniprot D4A3W9 837
organism: Rattus norvegicus

F-actin
type: Protein
entity reference: F-actin
feature: COMPLEX PARTICIPANT BINDING FEATURE s23 sa16 1115
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

Uncharacterized protein
type: ProteinReference
xref: uniprot F1MLJ8 990
xref: PTHR11309:SF23
organism: Bos taurus

uniprot Q5DRC8 633
type: UnificationXref
id: Q5DRC8
db: uniprot

uniprot Q9WV60 1088
type: UnificationXref
id: Q9WV60
db: uniprot

uniprot Q96292 385
type: UnificationXref
id: Q96292
db: uniprot

Protocadherin-16
type: ProteinReference
xref: PTHR24027:SF423
xref: uniprot D4ACX8 443
organism: Rattus norvegicus

uniprot O96863 41
type: UnificationXref
id: O96863
db: uniprot

uniprot A0A1D5RAI3 1061
type: UnificationXref
id: A0A1D5RAI3
db: uniprot

uniprot F6USP1 501
type: UnificationXref
id: F6USP1
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F7AAP1 519
xref: PTHR24027:SF96
organism: Monodelphis domestica

uniprot F7C1R7 526
type: UnificationXref
id: F7C1R7
db: uniprot

uniprot Q9NBW1 1050
type: UnificationXref
id: Q9NBW1
db: uniprot

uniprot P24257 912
type: UnificationXref
id: P24257
db: uniprot

PARTICIPANT STOICHIOMETRY r33 1157
type: Stoichiometry
physical entity: Wnt
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r33 1156
type: Stoichiometry
physical entity: Frizzled
stoichiometric coefficient: 1.0

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF91
xref: uniprot E1BEN9 841
organism: Bos taurus

Protocadherin-8
type: ProteinReference
xref: PTHR24028:SF46
xref: uniprot D3ZE55 437
organism: Rattus norvegicus

uniprot Q9UN67 732
type: UnificationXref
id: Q9UN67
db: uniprot

uniprot P10984 288
type: UnificationXref
id: P10984
db: uniprot

uniprot H2R817 888
type: UnificationXref
id: H2R817
db: uniprot

Tyrosine-protein kinase
type: ProteinReference
xref: PTHR24418:SF53
xref: uniprot E2RSH8 148
organism: Canis lupus familiaris

PARTICIPANT STOICHIOMETRY r33 1158
type: Stoichiometry
physical entity: Complex (Wnt/Frizzled)
stoichiometric coefficient: 1.0

uniprot Q9NPG4 719
type: UnificationXref
id: Q9NPG4
db: uniprot

Tyrosine-protein kinase Fer
type: ProteinReference
xref: uniprot P09760 159
xref: PTHR24418:SF227
organism: Rattus norvegicus

uniprot Q9ULB4 729
type: UnificationXref
id: Q9ULB4
db: uniprot

uniprot F7GZ76 547
type: UnificationXref
id: F7GZ76
db: uniprot

CDH18 isoform 2
type: ProteinReference
xref: uniprot H2QQP5 567
xref: PTHR24027:SF106
organism: Pan troglodytes

CDH10 isoform 1
type: ProteinReference
xref: PTHR24027:SF290
xref: uniprot H2QQP7 568
organism: Pan troglodytes

uniprot A0A2J8LQ46 813
type: UnificationXref
id: A0A2J8LQ46
db: uniprot

Cadherin 9
type: ProteinReference
xref: PTHR24027:SF99
xref: uniprot H2QQP8 569
organism: Pan troglodytes

uniprot H2QVA4 887
type: UnificationXref
id: H2QVA4
db: uniprot

Cadherin-2
type: ProteinReference
xref: uniprot Q90275 680
xref: PTHR24027:SF79
organism: Danio rerio

Y654 betacatenin s13 sa5 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y654
feature location: Y654 betacatenin s13 sa5 rs1 Y654
modification type: phosphorylated residue
comment: MODIFICATION_RESIDUE_ANGLE=3.3479165476195107
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=Y654

uniprot F7GBV2 540
type: UnificationXref
id: F7GBV2
db: uniprot

uniprot F6SCP4 249
type: UnificationXref
id: F6SCP4
db: uniprot

uniprot B1N2P0 203
type: UnificationXref
id: B1N2P0
db: uniprot

uniprot D3ZZZ9 795
type: UnificationXref
id: D3ZZZ9
db: uniprot

uniprot Q6IQV0 59
type: UnificationXref
id: Q6IQV0
db: uniprot

uniprot O35927 801
type: UnificationXref
id: O35927
db: uniprot

Protein CBG23090
type: ProteinReference
xref: uniprot A8Y4R0 194
xref: PTHR11937:SF470
organism: Caenorhabditis briggsae

uniprot O57328 1020
type: UnificationXref
id: O57328
db: uniprot

Protein Wnt
type: ProteinReference
xref: uniprot A0A0G2K3B7 805
xref: PTHR12027:SF73
organism: Rattus norvegicus

uniprot Q91VE5 686
type: UnificationXref
id: Q91VE5
db: uniprot

Cadherin
type: Protein
entity reference: Cadherin
feature: Y Cadherin s1 a10 rs1
feature: S T Cadherin s1 a10 rs2
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

Actin, aortic smooth muscle
type: ProteinReference
xref: uniprot P62736 316
xref: PTHR11937:SF201
organism: Homo sapiens

uniprot O00144 1019
type: UnificationXref
id: O00144
db: uniprot

Actin, aortic smooth muscle
type: ProteinReference
xref: PTHR11937:SF445
xref: uniprot P62739 318
organism: Bos taurus

uniprot P28466 917
type: UnificationXref
id: P28466
db: uniprot

uniprot Q7ZVF9 378
type: UnificationXref
id: Q7ZVF9
db: uniprot

Actin, aortic smooth muscle
type: ProteinReference
xref: PTHR11937:SF201
xref: uniprot P62737 317
organism: Mus musculus

uniprot F6U717 860
type: UnificationXref
id: F6U717
db: uniprot

Y654 betacatenin s30 sa17 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y654
feature location: Y654 betacatenin s30 sa17 rs1 Y654
comment: MODIFICATION_RESIDUE_ANGLE=3.3479165476195107
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=Y654

uniprot P67870 54
type: UnificationXref
id: P67870
db: uniprot

uniprot Q9Y6N8 783
type: UnificationXref
id: Q9Y6N8
db: uniprot

uniprot Q6DIV8 364
type: UnificationXref
id: Q6DIV8
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR24026:SF42
xref: uniprot A0A3Q1LJZ4 429
organism: Bos taurus

uniprot E2RM28 461
type: UnificationXref
id: E2RM28
db: uniprot

Frizzled class receptor 5
type: ProteinReference
xref: uniprot F1MGM1 989
xref: PTHR11309:SF136
organism: Bos taurus

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF33
xref: uniprot J9P5H0 892
organism: Canis lupus familiaris

Protocadherin-12
type: ProteinReference
xref: uniprot O55134 579
xref: PTHR24028:SF42
organism: Mus musculus

uniprot P60711 312
type: UnificationXref
id: P60711
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR24026:SF37
xref: uniprot F7E6Z1 534
organism: Macaca mulatta

Casein kinase 2 alpha 2
type: ProteinReference
xref: uniprot B4F7A9 14
xref: PTHR24054:SF34
organism: Rattus norvegicus

uniprot Q9U6V0 965
type: UnificationXref
id: Q9U6V0
db: uniprot

Anopheles gambiae
type: BioSource
xref: ncbitaxon 7165 62

uniprot A0A3Q1LJZ4 429
type: UnificationXref
id: A0A3Q1LJZ4
db: uniprot

uniprot F7G374 1069
type: UnificationXref
id: F7G374
db: uniprot

Protocadherin-7
type: ProteinReference
xref: PTHR24028:SF253
xref: uniprot O60245 580
organism: Homo sapiens

uniprot H2Q194 881
type: UnificationXref
id: H2Q194
db: uniprot

Cadherin-23
type: ProteinReference
xref: PTHR24025:SF18
xref: uniprot P58365 611
organism: Rattus norvegicus

Epidermal growth factor receptor
type: ProteinReference
xref: uniprot P04412 133
xref: PTHR24416:SF566
organism: Drosophila melanogaster

uniprot P55288 607
type: UnificationXref
id: P55288
db: uniprot

Protocadherin beta-14
type: ProteinReference
xref: PTHR24028:SF81
xref: uniprot Q9Y5E9 753
organism: Homo sapiens

uniprot Q5KP06 355
type: UnificationXref
id: Q5KP06
db: uniprot

Protocadherin beta-15
type: ProteinReference
xref: uniprot Q9Y5E8 752
xref: PTHR24028:SF97
organism: Homo sapiens

Cadherin-7
type: ProteinReference
xref: uniprot Q8BM92 667
xref: PTHR24027:SF91
organism: Mus musculus

Wnt Targetz transcription
type: Pathway

Protocadherin beta-14
type: ProteinReference
xref: PTHR24028:SF139
xref: uniprot Q6PB90 648
organism: Mus musculus

uniprot Q8BKG4 1041
type: UnificationXref
id: Q8BKG4
db: uniprot

uniprot F7GNE4 74
type: UnificationXref
id: F7GNE4
db: uniprot

uniprot M0R9D3 893
type: UnificationXref
id: M0R9D3
db: uniprot

Protocadherin beta 7
type: ProteinReference
xref: PTHR24028:SF148
xref: uniprot Q8CDY9 669
organism: Mus musculus

Protocadherin-9
type: ProteinReference
xref: uniprot F6WDU9 509
xref: PTHR24028:SF248
organism: Macaca mulatta

AGAP004166-PA
type: ProteinReference
xref: uniprot Q7PQL1 654
xref: PTHR24028:SF284
organism: Anopheles gambiae

Lymphoid enhancer binding factor 1
type: ProteinReference
xref: uniprot A0A3Q1MZ99 101
xref: PTHR10373:SF11
organism: Bos taurus

Protocadherin beta-5
type: ProteinReference
xref: PTHR24028:SF90
xref: uniprot Q9Y5E4 748
organism: Homo sapiens

Protocadherin beta-4
type: ProteinReference
xref: uniprot Q9Y5E5 749
xref: PTHR24028:SF55
organism: Homo sapiens

Protocadherin beta-3
type: ProteinReference
xref: PTHR24028:SF118
xref: uniprot Q9Y5E6 750
organism: Homo sapiens

Cadherin 9
type: ProteinReference
xref: PTHR24027:SF99
xref: uniprot E2R971 458
organism: Canis lupus familiaris

Proto-oncogene Wnt-1
type: ProteinReference
xref: PTHR12027:SF91
xref: uniprot P04426 902
organism: Mus musculus

Protocadherin beta-2
type: ProteinReference
xref: PTHR24028:SF281
xref: uniprot Q9Y5E7 751
organism: Homo sapiens

uniprot F6PMQ6 855
type: UnificationXref
id: F6PMQ6
db: uniprot

uniprot Q7TSK3 663
type: UnificationXref
id: Q7TSK3
db: uniprot

uniprot Q56A35 352
type: UnificationXref
id: Q56A35
db: uniprot

Protocadherin beta-7
type: ProteinReference
xref: PTHR24028:SF69
xref: uniprot Q9Y5E2 746
organism: Homo sapiens

Protocadherin beta-6
type: ProteinReference
xref: uniprot Q9Y5E3 747
xref: PTHR24028:SF104
organism: Homo sapiens

MODIFICATION FEATURE ubiquitinated
type: SequenceModificationVocabulary
comment: DATA_SOURCE=CellDesigner

uniprot A0A1D5QFE1 809
type: UnificationXref
id: A0A1D5QFE1
db: uniprot

uniprot E1BIM8 147
type: UnificationXref
id: E1BIM8
db: uniprot

Synechocystis
type: BioSource
xref: ncbitaxon 1111708 615

Cadherin s12 sa4 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Cadherin
stoichiometric coefficient: 1.0

Cadherin EGF LAG seven-pass G-type receptor 2
type: ProteinReference
xref: uniprot A0A2I3TB47 417
xref: PTHR24026:SF32
organism: Pan troglodytes

uniprot G3V819 879
type: UnificationXref
id: G3V819
db: uniprot

CDH8 isoform 8
type: ProteinReference
xref: uniprot H2QB90 562
xref: PTHR24027:SF273
organism: Pan troglodytes

PARTICIPANT STOICHIOMETRY r50 1151
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

uniprot P22725 909
type: UnificationXref
id: P22725
db: uniprot

PARTICIPANT STOICHIOMETRY r50 1152
type: Stoichiometry
physical entity: TCF/LEF
stoichiometric coefficient: 1.0

Uncharacterized protein
type: ProteinReference
xref: uniprot F7A7I3 258
xref: PTHR11937:SF477
organism: Monodelphis domestica

Uncharacterized protein
type: ProteinReference
xref: PTHR24027:SF425
xref: uniprot F7GVJ2 546
organism: Macaca mulatta

Protein Wnt-11
type: ProteinReference
xref: uniprot P49339 927
xref: PTHR12027:SF7
organism: Gallus gallus

uniprot O88689 585
type: UnificationXref
id: O88689
db: uniprot

PARTICIPANT STOICHIOMETRY r50 1153
type: Stoichiometry
physical entity: Complex (betacatenin/TCF/LEF)
stoichiometric coefficient: 1.0

Protein Wnt-4
type: ProteinReference
xref: uniprot P49337 926
xref: PTHR12027:SF101
organism: Gallus gallus

uniprot F1MJ55 25
type: UnificationXref
id: F1MJ55
db: uniprot

Cadherin-16
type: ProteinReference
xref: PTHR24028:SF1
xref: uniprot O75309 582
organism: Homo sapiens

uniprot P55290 609
type: UnificationXref
id: P55290
db: uniprot

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF100
xref: uniprot C3YZ17 828
organism: Branchiostoma floridae

uniprot Q9H158 712
type: UnificationXref
id: Q9H158
db: uniprot

Cadherin 20
type: ProteinReference
xref: uniprot E1BAM8 446
xref: PTHR24027:SF84
organism: Bos taurus

uniprot B0S6S2 982
type: UnificationXref
id: B0S6S2
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F7GZ76 547
xref: PTHR24028:SF42
organism: Macaca mulatta

Cadherin
type: Protein
entity reference: Cadherin
feature: COMPLEX PARTICIPANT BINDING FEATURE s14 sa8 1127
feature: S T Cadherin s14 sa8 rs2
feature: Y Cadherin s14 sa8 rs1
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

Predicted protein
type: ProteinReference
xref: uniprot A9TVP1 197
xref: PTHR11937:SF387
organism: Physcomitrella patens

uniprot F6RKF7 997
type: UnificationXref
id: F6RKF7
db: uniprot

uniprot C3YC50 220
type: UnificationXref
id: C3YC50
db: uniprot

ncbitaxon 9598 9
type: UnificationXref
id: 9598
db: ncbitaxon

Cadherin-3
type: ProteinReference
xref: uniprot P22223 594
xref: PTHR24027:SF267
organism: Homo sapiens

Uncharacterized protein
type: ProteinReference
xref: uniprot F6RKF7 997
xref: PTHR11309:SF34
organism: Monodelphis domestica

AGAP005569-PA
type: ProteinReference
xref: PTHR24054:SF0
xref: uniprot Q7Q707 61
organism: Anopheles gambiae

phosphorylated residue
type: SequenceModificationVocabulary
xref: 00696
comment: DATA_SOURCE=CellDesigner

Protein CBR-MOM-5
type: ProteinReference
xref: PTHR11309:SF47
xref: uniprot A8WWU4 980
organism: Caenorhabditis briggsae

uniprot H2QRU2 573
type: UnificationXref
id: H2QRU2
db: uniprot

Cadherin 17, LI cadherin (liver-intestine)
type: ProteinReference
xref: uniprot F1RD80 490
xref: PTHR24027:SF419
organism: Danio rerio

uniprot A4D7S0 817
type: UnificationXref
id: A4D7S0
db: uniprot

Protein Wnt
type: ProteinReference
xref: uniprot F6PJR9 854
xref: PTHR12027:SF70
organism: Macaca mulatta

Casein kinase II subunit beta
type: ProteinReference
xref: uniprot E9GTE8 24
xref: PTHR11740:SF0
organism: Daphnia pulex

alphacatenin
type: Protein
feature: COMPLEX PARTICIPANT BINDING FEATURE s17 sa11 1131
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

uniprot Q6IQL9 365
type: UnificationXref
id: Q6IQL9
db: uniprot

Protocadherin-9
type: ProteinReference
xref: uniprot Q9HC56 716
xref: PTHR24028:SF248
organism: Homo sapiens

Cadherin-20
type: ProteinReference
xref: uniprot Q9HBT6 715
xref: PTHR24027:SF84
organism: Homo sapiens

Protocadherin 1
type: ProteinReference
xref: uniprot E2QX93 454
xref: PTHR24028:SF247
organism: Canis lupus familiaris

uniprot A0A1D5Q1B1 974
type: UnificationXref
id: A0A1D5Q1B1
db: uniprot

uniprot F6SXE3 858
type: UnificationXref
id: F6SXE3
db: uniprot

uniprot Q9Y5F8 760
type: UnificationXref
id: Q9Y5F8
db: uniprot

Protocadherin-19
type: ProteinReference
xref: PTHR24028:SF40
xref: uniprot Q80TF3 664
organism: Mus musculus

Frizzled class receptor 8
type: ProteinReference
xref: uniprot F6VM33 1002
xref: PTHR11309:SF90
organism: Xenopus tropicalis

Actin
type: ProteinReference
xref: uniprot A2G1K5 173
xref: PTHR11937:SF387
organism: Trichomonas vaginalis

P00477
type: UnificationXref
id: P00477
db: PANTHER Pathway Component

Cadherin 24
type: ProteinReference
xref: uniprot E2QX22 453
xref: PTHR24027:SF272
organism: Canis lupus familiaris

Tyrosine-protein kinase Yes
type: ProteinReference
xref: uniprot Q28923 1077
xref: PTHR24418:SF90
organism: Canis lupus familiaris

Complex (Cadherin/betacatenin)
type: Complex
component stoichiometry: Cadherin s12 sa4 STOICHIOMETRY ID COMPLEX
component stoichiometry: betacatenin s13 sa5 STOICHIOMETRY ID COMPLEX
component: Cadherin
component: betacatenin
feature: COMPLEX BINDING FEATURE s53 a82 1106
feature: COMPLEX BINDING FEATURE s53 a82 1104
cellular location: cytoplasm

uniprot F6ZSZ9 126
type: UnificationXref
id: F6ZSZ9
db: uniprot

DISSOCIATION
type: InteractionVocabulary

Tyrosine-protein kinase
type: ProteinReference
xref: uniprot F1N261 1066
organism: Bos taurus

uniprot H2R2C6 1016
type: UnificationXref
id: H2R2C6
db: uniprot

P00470
type: UnificationXref
id: P00470
db: PANTHER Pathway Component

P00471
type: UnificationXref
id: P00471
db: PANTHER Pathway Component

P00472
type: UnificationXref
id: P00472
db: PANTHER Pathway Component

uniprot F6UDX0 500
type: UnificationXref
id: F6UDX0
db: uniprot

P00473
type: UnificationXref
id: P00473
db: PANTHER Pathway Component

P00474
type: UnificationXref
id: P00474
db: PANTHER Pathway Component

uniprot P63258 319
type: UnificationXref
id: P63258
db: uniprot

P00475
type: UnificationXref
id: P00475
db: PANTHER Pathway Component

Y654 betacatenin s16 sa10 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y654
feature location: Y654 betacatenin s16 sa10 rs1 Y654
comment: MODIFICATION_RESIDUE_ANGLE=3.3479165476195107
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=Y654

P00476
type: UnificationXref
id: P00476
db: PANTHER Pathway Component

uniprot Q5DRC4 630
type: UnificationXref
id: Q5DRC4
db: uniprot

Actin-2
type: ProteinReference
xref: uniprot Q8ILW9 383
xref: PTHR11937:SF387
organism: Plasmodium falciparum

uniprot Q553U6 349
type: UnificationXref
id: Q553U6
db: uniprot

uniprot A0A1D5Q352 403
type: UnificationXref
id: A0A1D5Q352
db: uniprot

uniprot F7FWN9 150
type: UnificationXref
id: F7FWN9
db: uniprot

uniprot Q05876 96
type: UnificationXref
id: Q05876
db: uniprot

Lymphoid enhancer-binding factor 1
type: ProteinReference
xref: uniprot F6WCX0 106
xref: PTHR10373:SF11
organism: Xenopus tropicalis

Glycogen synthase kinase 3 beta
type: ProteinReference
xref: uniprot A0A2I3SXI2 1079
xref: PTHR24057:SF8
organism: Pan troglodytes

uniprot F6WR53 149
type: UnificationXref
id: F6WR53
db: uniprot

uniprot F1MHG3 848
type: UnificationXref
id: F1MHG3
db: uniprot

uniprot P90623 340
type: UnificationXref
id: P90623
db: uniprot

P00466
type: UnificationXref
id: P00466
db: PANTHER Pathway Component

uniprot G3V8N7 555
type: UnificationXref
id: G3V8N7
db: uniprot

P00469
type: UnificationXref
id: P00469
db: PANTHER Pathway Component

P00468
type: UnificationXref
id: P00468
db: PANTHER Pathway Component

Homo sapiens
type: BioSource
xref: ncbitaxon 9606 49

betacatenin s119 a170 rs5
type: ModificationFeature
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=4.653633157668967
comment: MODIFICATION_RESIDUE_NAME=

Uncharacterized protein
type: ProteinReference
xref: uniprot F6S0B5 495
xref: PTHR24028:SF9
organism: Monodelphis domestica

CATALYSIS
type: Catalysis
controlled: DISSOCIATION_LEFT__Complex__Cadherin_betacatenin__alphacatenin_F_actin_-RIGHT__Complex__Cadherin_betacatenin_-_Complex__alphacatenin_F_actin_-_r21
controller: Src

uniprot F7BXD9 525
type: UnificationXref
id: F7BXD9
db: uniprot

uniprot O18840 275
type: UnificationXref
id: O18840
db: uniprot

Actin-1
type: ProteinReference
xref: uniprot P0DM41 285
xref: PTHR11937:SF387
organism: Caenorhabditis elegans

Complex (betacatenin/alphacatenin/ F-actin)
type: Complex
component stoichiometry: betacatenin s5 sa1 STOICHIOMETRY ID COMPLEX
component stoichiometry: alphacatenin s10 sa2 STOICHIOMETRY ID COMPLEX
component stoichiometry: F actin s11 sa3 STOICHIOMETRY ID COMPLEX
component: F-actin
component: alphacatenin
component: betacatenin
feature: COMPLEX BINDING FEATURE s41 a68 1124
feature: COMPLEX BINDING FEATURE s41 a68 1122
feature: COMPLEX BINDING FEATURE s41 a68 1120
cellular location: cytoplasm

Actin
type: ProteinReference
xref: PTHR11937:SF387
xref: uniprot A2FA04 170
organism: Trichomonas vaginalis

Catenin delta 2
type: ProteinReference
xref: uniprot A0A2I3RS45 792
organism: Pan troglodytes

uniprot F7ALP1 259
type: UnificationXref
id: F7ALP1
db: uniprot

uniprot P0C540 284
type: UnificationXref
id: P0C540
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR24028:SF247
xref: uniprot A0A1D5QHG9 404
organism: Macaca mulatta

PARTICIPANT STOICHIOMETRY r54 1190
type: Stoichiometry
physical entity: Complex (betacatenin/Tyrosine phosphatases/ P120)
stoichiometric coefficient: 1.0

Cadherin-10
type: ProteinReference
xref: PTHR24027:SF290
xref: uniprot A0A1D5PYV2 401
organism: Gallus gallus

uniprot P27782 110
type: UnificationXref
id: P27782
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR24027:SF423
xref: uniprot F7BXD9 525
organism: Macaca mulatta

uniprot Q7Q3J3 660
type: UnificationXref
id: Q7Q3J3
db: uniprot

uniprot D4ACX8 443
type: UnificationXref
id: D4ACX8
db: uniprot

uniprot Q7PQL1 654
type: UnificationXref
id: Q7PQL1
db: uniprot

Protocadherin-1
type: ProteinReference
xref: uniprot Q08174 618
xref: PTHR24028:SF247
organism: Homo sapiens

uniprot E2RH98 845
type: UnificationXref
id: E2RH98
db: uniprot

uniprot P28047 915
type: UnificationXref
id: P28047
db: uniprot

Complex (betacatenin/Tyrosine phosphatases/ P120)
type: Complex
component stoichiometry: Tyrosine phosphatases s33 sa18 STOICHIOMETRY ID COMPLEX
component stoichiometry: betacatenin s30 sa17 STOICHIOMETRY ID COMPLEX
component stoichiometry: P120 s34 sa19 STOICHIOMETRY ID COMPLEX
component: P120
component: betacatenin
component: Tyrosine phosphatases
feature: COMPLEX BINDING FEATURE s83 a118 1098
feature: COMPLEX BINDING FEATURE s83 a118 1094
feature: COMPLEX BINDING FEATURE s83 a118 1096
cellular location: cytoplasm

Cadherin
type: ProteinReference
xref: P00471
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Cadherin signaling pathway.PROTEIN.GENERIC.Cadherin
comment: ENTITY_REFERENCE_NOTES=Long Name: Cadherin Synonym: Synonym not specified Accession: P00471
member entity reference: Cadherin-15
member entity reference: Protocadherin beta-3
member entity reference: Cadherin-89D
member entity reference: Protocadherin-19
member entity reference: Protocadherin-18
member entity reference: Protocadherin beta-6
member entity reference: Protocadherin gamma-A6
member entity reference: Uncharacterized protein
member entity reference: Cadherin 24
member entity reference: Cadherin-3
member entity reference: Cadherin-related family member 1
member entity reference: Cadherin-2
member entity reference: Cadherin-22
member entity reference: Cadherin-7
member entity reference: Protocadherin 1
member entity reference: Cadherin 20
member entity reference: Cadherin 11
member entity reference: Protocadherin beta 9
member entity reference: Cadherin 6, type 2, K-cadherin (Fetal kidney)
member entity reference: Cadherin-9
member entity reference: Protocadherin Fat 3
member entity reference: Protocadherin beta-15
member entity reference: Protocadherin beta-16-like
member entity reference: Protocadherin 10
member entity reference: Protein dachsous
member entity reference: Cadherin 11, type 2, OB-cadherin (Osteoblast)
member entity reference: Protocadherin beta-14
member entity reference: Protocadherin Fat 2
member entity reference: Cadherin-10
member entity reference: CDH12 isoform 1
member entity reference: Protocadherin alpha-2
member entity reference: Protocadherin beta 15
member entity reference: Protocadherin beta-13
member entity reference: Protocadherin beta-12
member entity reference: MCG133388, isoform CRA_f
member entity reference: Protocadherin 7
member entity reference: Cadherin 18
member entity reference: Protocadherin beta-8
member entity reference: Protocadherin gamma-B4
member entity reference: Cadherin 74A, isoform A
member entity reference: Cadherin-18
member entity reference: Cadherin 3
member entity reference: Protocadherin beta-1
member entity reference: Cadherin-99C
member entity reference: Protocadherin gamma-A1
member entity reference: Protocadherin 19
member entity reference: FAT atypical cadherin 1
member entity reference: Cadherin-24
member entity reference: Cadherin-4
member entity reference: Protocadherin alpha-C1
member entity reference: AGAP002310-PA
member entity reference: Protocadherin alpha-4
member entity reference: Fat-like cadherin-related tumor suppressor homolog
member entity reference: Protocadherin 8
member entity reference: Protocadherin alpha-11

uniprot F1MLJ8 990
type: UnificationXref
id: F1MLJ8
db: uniprot

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF86
xref: uniprot F7E738 870
organism: Macaca mulatta

HETERODIMER_ASSOCIATION_LEFT__Frizzled-_Wnt-RIGHT__Complex__Wnt_Frizzled_-_r33
type: ComplexAssembly
spontaneous: true
conversion direction: LEFT_TO_RIGHT
xref: HETERODIMER ASSOCIATION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r33 1156
participant stoichiometry: PARTICIPANT STOICHIOMETRY r33 1158
participant stoichiometry: PARTICIPANT STOICHIOMETRY r33 1157
left: Wnt
left: Frizzled
interaction type: HETERODIMER_ASSOCIATION
right: Complex (Wnt/Frizzled)

uniprot H2R283 788
type: UnificationXref
id: H2R283
db: uniprot

CDH5 isoform 1
type: ProteinReference
xref: PTHR24027:SF89
xref: uniprot A0A2J8MVE2 423
organism: Pan troglodytes

uniprot H2RAM0 889
type: UnificationXref
id: H2RAM0
db: uniprot

ncbitaxon 9544 5
type: UnificationXref
id: 9544
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r54 1187
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF82
xref: uniprot F1N5R1 851
organism: Bos taurus

PARTICIPANT STOICHIOMETRY r54 1188
type: Stoichiometry
physical entity: Tyrosine phosphatases
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r54 1189
type: Stoichiometry
physical entity: P120
stoichiometric coefficient: 1.0

uniprot A7SG27 10
type: UnificationXref
id: A7SG27
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot W4Y969 392
xref: PTHR11937:SF453
organism: Strongylocentrotus purpuratus

uniprot A0A2I3TGC6 975
type: UnificationXref
id: A0A2I3TGC6
db: uniprot

Cadherin s14 sa8 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Cadherin
stoichiometric coefficient: 2.0

Actin-12
type: ProteinReference
xref: PTHR11937:SF434
xref: uniprot P53497 305
organism: Arabidopsis thaliana

uniprot F1P8N3 156
type: UnificationXref
id: F1P8N3
db: uniprot

uniprot P33151 596
type: UnificationXref
id: P33151
db: uniprot

Actin-4
type: ProteinReference
xref: uniprot P53494 304
xref: PTHR11937:SF438
organism: Arabidopsis thaliana

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF98
xref: uniprot Q7PM77 950
organism: Anopheles gambiae

Actin-7
type: ProteinReference
xref: PTHR11937:SF483
xref: uniprot P53492 302
organism: Arabidopsis thaliana

uniprot C3XYD3 217
type: UnificationXref
id: C3XYD3
db: uniprot

uniprot A7SCN8 182
type: UnificationXref
id: A7SCN8
db: uniprot

Frizzled class receptor 2
type: ProteinReference
xref: PTHR11309:SF34
xref: uniprot F1QBI2 993
organism: Danio rerio

uniprot P60709 310
type: UnificationXref
id: P60709
db: uniprot

ACTin
type: ProteinReference
xref: PTHR11937:SF359
xref: uniprot O45815 277
organism: Caenorhabditis elegans

uniprot Q9Y5E4 748
type: UnificationXref
id: Q9Y5E4
db: uniprot

Actin-related protein 2
type: ProteinReference
xref: PTHR11937:SF37
xref: uniprot P53489 301
organism: Caenorhabditis elegans

ncbitaxon 7227 42
type: UnificationXref
id: 7227
db: ncbitaxon

betacatenin
type: Protein
entity reference: betacatenin
feature: Y142 betacatenin s28 sa22 rs2
feature: Y654 betacatenin s28 sa22 rs1
feature: T112 betacatenin s28 sa22 rs3
feature: betacatenin s28 sa22 rs5
feature: S betacatenin s28 sa22 rs4
feature: COMPLEX PARTICIPANT BINDING FEATURE s28 sa22 1091
cellular location: nucleus
comment: SPECIES_TYPE=PROTEIN

uniprot Q13467 1028
type: UnificationXref
id: Q13467
db: uniprot

uniprot Q10DV7 344
type: UnificationXref
id: Q10DV7
db: uniprot

Cadherin EGF LAG seven-pass G-type receptor 3
type: ProteinReference
xref: PTHR24026:SF38
xref: uniprot Q91ZI0 703
organism: Mus musculus

alphacatenin
type: Protein
feature: COMPLEX PARTICIPANT BINDING FEATURE s2 sa6 1101
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

betacatenin s20 sa14 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

Novel actin protein
type: ProteinReference
xref: PTHR11937:SF176
xref: uniprot Q6IQL9 365
organism: Danio rerio

HETERODIMER_ASSOCIATION
type: InteractionVocabulary

uniprot P47793 923
type: UnificationXref
id: P47793
db: uniprot

Yes
type: Protein
entity reference: Yes
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

Actin-related protein 2
type: ProteinReference
xref: PTHR11937:SF37
xref: uniprot P53488 300
organism: Gallus gallus

FZD5 isoform 1
type: ProteinReference
xref: uniprot H2QJA9 1014
xref: PTHR11309:SF136
organism: Pan troglodytes

uniprot F6WCX0 106
type: UnificationXref
id: F6WCX0
db: uniprot

uniprot F1REQ8 491
type: UnificationXref
id: F1REQ8
db: uniprot

uniprot Q924A0 112
type: UnificationXref
id: Q924A0
db: uniprot

Dachsous cadherin-related 1
type: ProteinReference
xref: uniprot F6Y4F1 514
xref: PTHR24027:SF423
organism: Canis lupus familiaris

uniprot A5D7F4 435
type: UnificationXref
id: A5D7F4
db: uniprot

Actin, cytoplasmic type 5
type: ProteinReference
xref: uniprot P53478 299
xref: PTHR11937:SF168
organism: Gallus gallus

uniprot Q5DRD8 639
type: UnificationXref
id: Q5DRD8
db: uniprot

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF91
xref: uniprot F6X3B2 862
organism: Xenopus tropicalis

PARTICIPANT STOICHIOMETRY r21 1148
type: Stoichiometry
physical entity: Complex (alphacatenin/F-actin)
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r21 1147
type: Stoichiometry
physical entity: Complex (Cadherin/betacatenin)
stoichiometric coefficient: 1.0

uniprot O60716 802
type: UnificationXref
id: O60716
db: uniprot

IC
type: EvidenceCodeVocabulary
xref: eco ECO:0000305 172

uniprot F6RN85 29
type: UnificationXref
id: F6RN85
db: uniprot

PARTICIPANT STOICHIOMETRY r21 1146
type: Stoichiometry
physical entity: Complex (Cadherin/betacatenin/ alphacatenin/F-actin)
stoichiometric coefficient: 1.0

Frizzled
type: ProteinReference
xref: PTHR11309:SF47
xref: uniprot P18537 1025
organism: Drosophila melanogaster

uniprot B3DIG4 983
type: UnificationXref
id: B3DIG4
db: uniprot

uniprot H2QQP5 567
type: UnificationXref
id: H2QQP5
db: uniprot

uniprot Q9WTR5 745
type: UnificationXref
id: Q9WTR5
db: uniprot

uniprot P19784 48
type: UnificationXref
id: P19784
db: uniprot

uniprot P67874 56
type: UnificationXref
id: P67874
db: uniprot

uniprot A0A0G2K8I5 396
type: UnificationXref
id: A0A0G2K8I5
db: uniprot

uniprot E2R9M9 986
type: UnificationXref
id: E2R9M9
db: uniprot

Tyrosine-protein kinase Yes
type: ProteinReference
xref: PTHR24418:SF90
xref: uniprot P09324 1073
organism: Gallus gallus

ncbitaxon 227321 295
type: UnificationXref
id: 227321
db: ncbitaxon

Actin, cytoskeletal 3A
type: ProteinReference
xref: uniprot P53474 298
xref: PTHR11937:SF387
organism: Strongylocentrotus purpuratus

Receptor tyrosine-protein kinase erbB-2
type: ProteinReference
xref: PTHR24416:SF137
xref: uniprot O18735 131
organism: Canis lupus familiaris

Protein Wnt-7b
type: ProteinReference
xref: uniprot P28047 915
xref: PTHR12027:SF73
organism: Mus musculus

Actin
type: ProteinReference
xref: uniprot B3RKR4 205
xref: PTHR11937:SF387
organism: Trichoplax adhaerens

P00463
type: UnificationXref
id: P00463
db: PANTHER Pathway Component

P00462
type: UnificationXref
id: P00462
db: PANTHER Pathway Component

Protein Wnt
type: ProteinReference
xref: uniprot A0A1D5RE70 811
xref: PTHR12027:SF76
organism: Macaca mulatta

P00465
type: UnificationXref
id: P00465
db: PANTHER Pathway Component

uniprot Q7Q707 61
type: UnificationXref
id: Q7Q707
db: uniprot

P00464
type: UnificationXref
id: P00464
db: PANTHER Pathway Component

uniprot F7BUJ8 524
type: UnificationXref
id: F7BUJ8
db: uniprot

uniprot F7HLC0 549
type: UnificationXref
id: F7HLC0
db: uniprot

uniprot F6Y191 513
type: UnificationXref
id: F6Y191
db: uniprot

uniprot P70424 138
type: UnificationXref
id: P70424
db: uniprot

uniprot Q9Y5E8 752
type: UnificationXref
id: Q9Y5E8
db: uniprot

uniprot F6S1W0 496
type: UnificationXref
id: F6S1W0
db: uniprot

uniprot F6QAW3 995
type: UnificationXref
id: F6QAW3
db: uniprot

uniprot Q75NI5 651
type: UnificationXref
id: Q75NI5
db: uniprot

uniprot F7CDC6 1004
type: UnificationXref
id: F7CDC6
db: uniprot

uniprot P55280 600
type: UnificationXref
id: P55280
db: uniprot

Protocadherin beta-7-like
type: ProteinReference
xref: PTHR24028:SF69
xref: uniprot F2Z3R8 493
organism: Rattus norvegicus

Frizzled
type: Protein
entity reference: Frizzled
feature: COMPLEX PARTICIPANT BINDING FEATURE s27 sa21 1137
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

uniprot O70421 1022
type: UnificationXref
id: O70421
db: uniprot

uniprot Q19194 623
type: UnificationXref
id: Q19194
db: uniprot

Protocadherin beta 1
type: ProteinReference
xref: PTHR24028:SF12
xref: uniprot F2Z3R5 492
organism: Rattus norvegicus

uniprot P62736 316
type: UnificationXref
id: P62736
db: uniprot

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF78
xref: uniprot J9P2Q5 891
organism: Canis lupus familiaris

AGAP001591-PA
type: ProteinReference
xref: uniprot Q7PUW9 657
xref: PTHR24028:SF298
organism: Anopheles gambiae

uniprot P63260 321
type: UnificationXref
id: P63260
db: uniprot

Neuronal proto-oncogene tyrosine-protein kinase Src
type: ProteinReference
xref: PTHR24418:SF53
xref: uniprot P05480 152
organism: Mus musculus

uniprot A0NBC9 433
type: UnificationXref
id: A0NBC9
db: uniprot

Cadherin
type: Protein
entity reference: Cadherin
feature: COMPLEX PARTICIPANT BINDING FEATURE s12 sa4 1105
feature: S T Cadherin s12 sa4 rs2
feature: Y Cadherin s12 sa4 rs1
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

Uncharacterized protein
type: ProteinReference
xref: uniprot C3YKS6 221
organism: Branchiostoma floridae

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF94
xref: uniprot D3ZND6 834
organism: Rattus norvegicus

uniprot P70408 613
type: UnificationXref
id: P70408
db: uniprot

Cadherin 74A, isoform A
type: ProteinReference
xref: PTHR24026:SF106
xref: uniprot Q9VVG0 743
organism: Drosophila melanogaster

KNOWN_TRANSITION_OMITTED
type: RelationshipTypeVocabulary

uniprot E1BNE0 155
type: UnificationXref
id: E1BNE0
db: uniprot

uniprot P40589 920
type: UnificationXref
id: P40589
db: uniprot

Tyrosine-protein phosphatase non-receptor type 1
type: ProteinReference
xref: uniprot P35821 791
organism: Mus musculus

uniprot Q9VAF5 740
type: UnificationXref
id: Q9VAF5
db: uniprot

uniprot G3N2W8 1009
type: UnificationXref
id: G3N2W8
db: uniprot

uniprot A0A0G2K6Q8 806
type: UnificationXref
id: A0A0G2K6Q8
db: uniprot

Actin, beta-like 2
type: ProteinReference
xref: uniprot D3ZRN3 228
xref: PTHR11937:SF168
organism: Rattus norvegicus

uniprot Q5M8T9 358
type: UnificationXref
id: Q5M8T9
db: uniprot

uniprot Q91V48 684
type: UnificationXref
id: Q91V48
db: uniprot

Protein CBR-KIN-3
type: ProteinReference
xref: uniprot A8XFP5 12
xref: PTHR24054:SF0
organism: Caenorhabditis briggsae

Protein Wnt
type: ProteinReference
xref: uniprot F6U717 860
xref: PTHR12027:SF92
organism: Macaca mulatta

PTHR12027:SF111
type: RelationshipXref
id: PTHR12027:SF111
db: PANTHER Family
relationship type: By Homology

uniprot Q9HC56 716
type: UnificationXref
id: Q9HC56
db: uniprot

PTHR12027:SF112
type: RelationshipXref
id: PTHR12027:SF112
db: PANTHER Family
relationship type: By Homology

uniprot Q9HBT6 715
type: UnificationXref
id: Q9HBT6
db: uniprot

Actin, putative (Fragment)
type: ProteinReference
xref: uniprot B7PBG2 209
xref: PTHR11937:SF387
organism: Ixodes scapularis

EGFR
type: ProteinReference
xref: P00466
standard name: Epidermal growth factor receptor
comment: ENTITY_REFERENCE_ID_DESC=Cadherin signaling pathway.PROTEIN.RECEPTOR.EGFR
comment: ENTITY_REFERENCE_NOTES=Long Name: Epidermal growth factor receptor Synonym: Synonym not specified Accession: P00466
comment: ENTITY_REFERENCE_PROTEIN_TYPE=RECEPTOR
member entity reference: Epidermal growth factor receptor
member entity reference: Receptor tyrosine-protein kinase erbB-3
member entity reference: Receptor tyrosine-protein kinase erbB-2
member entity reference: Receptor protein-tyrosine kinase
member entity reference: Receptor tyrosine-protein kinase erbB-4
member entity reference: Uncharacterized protein
member entity reference: ERBB3 protein
member entity reference: Receptor protein-tyrosine kinase (Fragment)

uniprot Q96JQ0 706
type: UnificationXref
id: Q96JQ0
db: uniprot

uniprot A0A3Q2TVV5 1080
type: UnificationXref
id: A0A3Q2TVV5
db: uniprot

ncbitaxon 54126 168
type: UnificationXref
id: 54126
db: ncbitaxon

PTHR24028:SF9
type: RelationshipXref
id: PTHR24028:SF9
db: PANTHER Family
relationship type: By Homology

uniprot Q9I8V1 386
type: UnificationXref
id: Q9I8V1
db: uniprot

uniprot Q8BFZ3 380
type: UnificationXref
id: Q8BFZ3
db: uniprot

Cadherin 88C
type: ProteinReference
xref: uniprot Q9VFH5 742
xref: PTHR24028:SF298
organism: Drosophila melanogaster

PTHR24028:SF1
type: RelationshipXref
id: PTHR24028:SF1
db: PANTHER Family
relationship type: By Homology

uniprot Q9Y5I4 782
type: UnificationXref
id: Q9Y5I4
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF446
xref: uniprot C3YC50 220
organism: Branchiostoma floridae

uniprot Q9Y5F1 755
type: UnificationXref
id: Q9Y5F1
db: uniprot

uniprot Q12841 937
type: UnificationXref
id: Q12841
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR24028:SF247
xref: uniprot A0A3Q1M024 431
organism: Bos taurus

PTHR12027:SF100
type: RelationshipXref
id: PTHR12027:SF100
db: PANTHER Family
relationship type: By Homology

uniprot Q65XH8 361
type: UnificationXref
id: Q65XH8
db: uniprot

Protein Wnt
type: ProteinReference
xref: uniprot H2Q2F4 882
xref: PTHR12027:SF94
organism: Pan troglodytes

PTHR12027:SF101
type: RelationshipXref
id: PTHR12027:SF101
db: PANTHER Family
relationship type: By Homology

PTHR12027:SF102
type: RelationshipXref
id: PTHR12027:SF102
db: PANTHER Family
relationship type: By Homology

uniprot F6UDX9 254
type: UnificationXref
id: F6UDX9
db: uniprot

uniprot F6Y5X3 515
type: UnificationXref
id: F6Y5X3
db: uniprot

Lymphoid enhancer binding factor 1
type: ProteinReference
xref: PTHR10373:SF11
xref: uniprot A0A2I3SSM9 100
organism: Pan troglodytes

PTHR12027:SF105
type: RelationshipXref
id: PTHR12027:SF105
db: PANTHER Family
relationship type: By Homology

uniprot G3V8P3 557
type: UnificationXref
id: G3V8P3
db: uniprot

Protein Wnt
type: ProteinReference
xref: uniprot M0R9D3 893
xref: PTHR12027:SF78
organism: Rattus norvegicus

uniprot Q5DWV2 644
type: UnificationXref
id: Q5DWV2
db: uniprot

PTHR24028:SF0
type: RelationshipXref
id: PTHR24028:SF0
db: PANTHER Family
relationship type: By Homology

uniprot A0A2I3SIH9 146
type: UnificationXref
id: A0A2I3SIH9
db: uniprot

KNOWN_TRANSITION_OMITTED
type: InteractionVocabulary

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF70
xref: uniprot H2QVA4 887
organism: Pan troglodytes

uniprot C3XZ13 219
type: UnificationXref
id: C3XZ13
db: uniprot

uniprot F1LMI3 467
type: UnificationXref
id: F1LMI3
db: uniprot

uniprot P08181 43
type: UnificationXref
id: P08181
db: uniprot

Protocadherin-8
type: ProteinReference
xref: PTHR24028:SF46
xref: uniprot Q7TSK3 663
organism: Mus musculus

uniprot F7AIP6 108
type: UnificationXref
id: F7AIP6
db: uniprot

uniprot F0Z796 236
type: UnificationXref
id: F0Z796
db: uniprot

Leishmania major
type: BioSource
xref: ncbitaxon 5664 388

uniprot F7GRQ5 543
type: UnificationXref
id: F7GRQ5
db: uniprot

uniprot P48615 925
type: UnificationXref
id: P48615
db: uniprot

uniprot Q8BM92 667
type: UnificationXref
id: Q8BM92
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF192
xref: uniprot F6TUR3 251
organism: Monodelphis domestica

CDH3 isoform 2
type: ProteinReference
xref: uniprot H2QBE4 563
xref: PTHR24027:SF267
organism: Pan troglodytes

uniprot F6VEV5 506
type: UnificationXref
id: F6VEV5
db: uniprot

Cadherin s24 sa24 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Cadherin
stoichiometric coefficient: 1.0

Protein Wnt
type: ProteinReference
xref: uniprot H2QJF8 886
xref: PTHR12027:SF89
organism: Pan troglodytes

Fyn
type: Protein
entity reference: Fyn
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

uniprot A7SEB1 184
type: UnificationXref
id: A7SEB1
db: uniprot

uniprot P63267 323
type: UnificationXref
id: P63267
db: uniprot

Catenin beta-1
type: ProteinReference
xref: uniprot Q0VCX4 79
xref: PTHR45976:SF4
organism: Bos taurus

Protocadherin 1
type: ProteinReference
xref: uniprot A0A2I3REF9 409
xref: PTHR24028:SF247
organism: Pan troglodytes

uniprot Q9Y5E5 749
type: UnificationXref
id: Q9Y5E5
db: uniprot

uniprot Q91398 67
type: UnificationXref
id: Q91398
db: uniprot

Src
type: ProteinReference
xref: P00468
standard name: Src tyrosine kinase
comment: ENTITY_REFERENCE_ID_DESC=Cadherin signaling pathway.PROTEIN.GENERIC.Src
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Src tyrosine kinase Synonym: Synonym not specified Accession: P00468
member entity reference: Tyrosine-protein kinase
member entity reference: Neuronal proto-oncogene tyrosine-protein kinase Src
member entity reference: Proto-oncogene tyrosine-protein kinase Src

Y654 betacatenin s28 sa22 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y654
feature location: Y654 betacatenin s28 sa22 rs1 Y654
comment: MODIFICATION_RESIDUE_ANGLE=3.3479165476195107
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=Y654

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF387
xref: uniprot H2KNE6 267
organism: Phaeosphaeria nodorum

uniprot Q9W6E3 1059
type: UnificationXref
id: Q9W6E3
db: uniprot

Muscle-specific actin
type: ProteinReference
xref: uniprot E9FRT1 232
xref: PTHR11937:SF162
organism: Daphnia pulex

Casein kinase II subunit alpha'
type: ProteinReference
xref: PTHR24054:SF34
xref: uniprot O54833 39
organism: Mus musculus

Tyrosine-protein kinase Lyn
type: ProteinReference
xref: uniprot Q07014 1076
organism: Rattus norvegicus

uniprot P05480 152
type: UnificationXref
id: P05480
db: uniprot

Lymphocyte enhancer binding factor 1
type: ProteinReference
xref: uniprot Q9W7C0 117
xref: PTHR10373:SF11
organism: Danio rerio

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF201
xref: uniprot F7DQK7 262
organism: Monodelphis domestica

Actin 7
type: ProteinReference
xref: PTHR11937:SF387
xref: uniprot A9TBG2 195
organism: Physcomitrella patens

Y142 betacatenin s111 a157 rs2
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y142
feature location: Y142 betacatenin s111 a157 rs2 Y142
comment: MODIFICATION_RESIDUE_NAME=Y142
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=2.893781136851091

uniprot Q9YGX6 970
type: UnificationXref
id: Q9YGX6
db: uniprot

uniprot Q9Y5H3 771
type: UnificationXref
id: Q9Y5H3
db: uniprot

uniprot P43446 922
type: UnificationXref
id: P43446
db: uniprot

uniprot P04626 134
type: UnificationXref
id: P04626
db: uniprot

uniprot H2R453 1070
type: UnificationXref
id: H2R453
db: uniprot

uniprot Q6P378 367
type: UnificationXref
id: Q6P378
db: uniprot

Actin
type: ProteinReference
xref: PTHR11937:SF387
xref: uniprot Q5KP06 355
organism: Cryptococcus neoformans

Actin, gamma-enteric smooth muscle
type: ProteinReference
xref: uniprot Q5E9B5 354
xref: PTHR11937:SF201
organism: Bos taurus

PTHR24028:SF110
type: RelationshipXref
id: PTHR24028:SF110
db: PANTHER Family
relationship type: By Homology

F actin s18 sa12 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: F-actin
stoichiometric coefficient: 1.0

Actin, alpha skeletal muscle
type: ProteinReference
xref: PTHR11937:SF193
xref: uniprot P68134 332
organism: Mus musculus

Lymphoid enhancer binding factor 1
type: ProteinReference
xref: PTHR10373:SF11
xref: uniprot F1Q334 104
organism: Canis lupus familiaris

Actin, alpha skeletal muscle
type: ProteinReference
xref: PTHR11937:SF193
xref: uniprot P68133 331
organism: Homo sapiens

alphacatenin s17 sa11 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: alphacatenin
stoichiometric coefficient: 1.0

Protein Wnt-6
type: ProteinReference
xref: PTHR12027:SF72
xref: uniprot P22727 911
organism: Mus musculus

Actin, alpha skeletal muscle
type: ProteinReference
xref: PTHR11937:SF193
xref: uniprot P68136 333
organism: Rattus norvegicus

uniprot A0A2J8KU53 422
type: UnificationXref
id: A0A2J8KU53
db: uniprot

uniprot H2QRP0 572
type: UnificationXref
id: H2QRP0
db: uniprot

Protein Wnt-5b
type: ProteinReference
xref: uniprot P22726 910
xref: PTHR12027:SF87
organism: Mus musculus

Protein Wnt-5a
type: ProteinReference
xref: PTHR12027:SF33
xref: uniprot P22725 909
organism: Mus musculus

Actin, alpha skeletal muscle
type: ProteinReference
xref: uniprot P68138 334
xref: PTHR11937:SF193
organism: Bos taurus

uniprot Q9ULW2 1056
type: UnificationXref
id: Q9ULW2
db: uniprot

Protein Wnt-4
type: ProteinReference
xref: PTHR12027:SF101
xref: uniprot P22724 908
organism: Mus musculus

Actin, alpha skeletal muscle
type: ProteinReference
xref: uniprot P68139 335
xref: PTHR11937:SF193
organism: Gallus gallus

uniprot P22727 911
type: UnificationXref
id: P22727
db: uniprot

uniprot F7HN04 550
type: UnificationXref
id: F7HN04
db: uniprot

uniprot Q71M42 650
type: UnificationXref
id: Q71M42
db: uniprot

PTHR24028:SF119
type: RelationshipXref
id: PTHR24028:SF119
db: PANTHER Family
relationship type: By Homology

PARTICIPANT STOICHIOMETRY r53 1140
type: Stoichiometry
physical entity: Complex (Cadherin/betacatenin)
stoichiometric coefficient: 1.0

Protein Wnt-10b
type: ProteinReference
xref: PTHR12027:SF76
xref: uniprot Q801F7 951
organism: Danio rerio

Cadherin signaling pathway
type: Pathway
pathway component: HETERODIMER_ASSOCIATION_LEFT__Cadherin-_P120-RIGHT__Complex__Cadherin_P120_-_r44
pathway component: TRANSPORT_LEFT__betacatenin-RIGHT__betacatenin-_r51
pathway component: TRANSPORT_LEFT__betacatenin-RIGHT__betacatenin-_r47
pathway component: TRANSPORT_LEFT__betacatenin-RIGHT__betacatenin-_r49
pathway component: STATE_TRANSITION_LEFT__betacatenin-RIGHT__betacatenin-_r39
pathway component: TRANSPORT_LEFT__betacatenin-RIGHT__betacatenin-_r52
pathway component: PHYSICAL_STIMULATION
pathway component: STATE_TRANSITION_LEFT__betacatenin-RIGHT__betacatenin-_r25
pathway component: TRIGGER
pathway component: HETERODIMER_ASSOCIATION_LEFT__Cadherin-_Complex__Cadherin_betacatenin__alphacatenin_F_actin_-RIGHT__Complex__Cadherin_Cadherin__betacatenin_alphacatenin__F_actin_-_r22
pathway component: DISSOCIATION_LEFT__Complex__betacatenin_alphacatenin__F_actin_-RIGHT__betacatenin-_F_actin-_alphacatenin-_r46
pathway component: HETERODIMER_ASSOCIATION_LEFT__betacatenin-_Tyrosine_phosphatases-_P120-RIGHT__Complex__betacatenin_Tyrosine_phosphatases__P120_-_r54
pathway component: STATE_TRANSITION_LEFT__Fer-RIGHT__Fer-_r12
pathway component: KNOWN_TRANSITION_OMITTED_LEFT__betacatenin-RIGHT__betacatenin-_r24
pathway component: DISSOCIATION_LEFT__Complex__Cadherin_betacatenin__alphacatenin_F_actin_-RIGHT__Cadherin-_Complex__betacatenin_alphacatenin__F_actin_-_r43
pathway component: HETERODIMER_ASSOCIATION_LEFT__Frizzled-_Wnt-RIGHT__Complex__Wnt_Frizzled_-_r33
pathway component: HETERODIMER_ASSOCIATION_LEFT__Cadherin-_betacatenin-RIGHT__Complex__Cadherin_betacatenin_-_r53
pathway component: DISSOCIATION_LEFT__Complex__Cadherin_betacatenin__alphacatenin_F_actin_-RIGHT__Complex__Cadherin_betacatenin_-_Complex__alphacatenin_F_actin_-_r21
pathway component: TRANSPORT_LEFT__betacatenin-RIGHT__betacatenin-_r48
pathway component: HETERODIMER_ASSOCIATION_LEFT__betacatenin-_TCF_LEF-RIGHT__Complex__betacatenin_TCF_LEF_-_r50
pathway component: STATE_TRANSITION_LEFT__betacatenin-RIGHT__a133_degraded-_r23
pathway component: HETERODIMER_ASSOCIATION_LEFT__Cadherin-_Complex__betacatenin_alphacatenin__F_actin_-RIGHT__Complex__Cadherin_betacatenin__alphacatenin_F_actin_-_r42
pathway component: HETERODIMER_ASSOCIATION_LEFT__Complex__Cadherin_betacatenin_-_Complex__alphacatenin_F_actin_-RIGHT__Complex__Cadherin_Cadherin__betacatenin_alphacatenin__F_actin_-_r17
xref: PANTHER Pathway P00012 1
comment: MODEL_NOTES=Panther Pathway: P00012 The cadherin gene family encode proteins that mediate calcium-ion-dependent adhesion. Three members of this family are E-cadherin, N-cadherin, and P-cadherin. Cadherin-catenin complex is the central part of this pathway. It's been shown that the pathway is involved in many biological processes, such as development, neurogenesis, cell adhesion, and inflammation. It has also been implicated to ve involved in many disease, such as cancer. In this pathway, we focus on Cadherin signaling pathway. For Wnt pathway, please see our "Wnt signaling pathway". Medline=12841864 Medline=12925579 Medline=15001769 Medline=7502046 OMIM=114020 PMID: 12841864 PMID: 12925579 PMID: 15001769 PMID: 7502046

PTHR24028:SF118
type: RelationshipXref
id: PTHR24028:SF118
db: PANTHER Family
relationship type: By Homology

PTHR11309:SF136
type: RelationshipXref
id: PTHR11309:SF136
db: PANTHER Family
relationship type: By Homology

PTHR24028:SF117
type: RelationshipXref
id: PTHR24028:SF117
db: PANTHER Family
relationship type: By Homology

PTHR11309:SF137
type: RelationshipXref
id: PTHR11309:SF137
db: PANTHER Family
relationship type: By Homology

uniprot F7HKD3 877
type: UnificationXref
id: F7HKD3
db: uniprot

PTHR24028:SF111
type: RelationshipXref
id: PTHR24028:SF111
db: PANTHER Family
relationship type: By Homology

PTHR11309:SF139
type: RelationshipXref
id: PTHR11309:SF139
db: PANTHER Family
relationship type: By Homology

PTHR24028:SF113
type: RelationshipXref
id: PTHR24028:SF113
db: PANTHER Family
relationship type: By Homology

Uncharacterized protein
type: ProteinReference
xref: PTHR24027:SF290
xref: uniprot F7BIQ7 523
organism: Monodelphis domestica

Actin-related protein 2
type: ProteinReference
xref: PTHR11937:SF37
xref: uniprot I2CYF0 274
organism: Macaca mulatta

uniprot Q92048 953
type: UnificationXref
id: Q92048
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F1PVD5 489
xref: PTHR24027:SF84
organism: Canis lupus familiaris

Giardia intestinalis
type: BioSource
xref: ncbitaxon 184922 186

PARTICIPANT STOICHIOMETRY r53 1138
type: Stoichiometry
physical entity: Cadherin
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r53 1139
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

uniprot F2Z4N8 245
type: UnificationXref
id: F2Z4N8
db: uniprot

Protocadherin 1
type: ProteinReference
xref: uniprot F7ET26 536
xref: PTHR24028:SF247
organism: Monodelphis domestica

S betacatenin s20 sa14 rs4
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY S
feature location: S betacatenin s20 sa14 rs4 S
comment: MODIFICATION_RESIDUE_NAME=S
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=1.6575346654708816

PTHR11309:SF140
type: RelationshipXref
id: PTHR11309:SF140
db: PANTHER Family
relationship type: By Homology

Protocadherin 7
type: ProteinReference
xref: PTHR24028:SF253
xref: uniprot A0A0A6YY83 394
organism: Mus musculus

PTHR11309:SF141
type: RelationshipXref
id: PTHR11309:SF141
db: PANTHER Family
relationship type: By Homology

PTHR24028:SF108
type: RelationshipXref
id: PTHR24028:SF108
db: PANTHER Family
relationship type: By Homology

uniprot F2Z3R8 493
type: UnificationXref
id: F2Z3R8
db: uniprot

PTHR24028:SF107
type: RelationshipXref
id: PTHR24028:SF107
db: PANTHER Family
relationship type: By Homology

PTHR24028:SF106
type: RelationshipXref
id: PTHR24028:SF106
db: PANTHER Family
relationship type: By Homology

PTHR24028:SF105
type: RelationshipXref
id: PTHR24028:SF105
db: PANTHER Family
relationship type: By Homology

PTHR24028:SF104
type: RelationshipXref
id: PTHR24028:SF104
db: PANTHER Family
relationship type: By Homology

Protein Wnt
type: ProteinReference
xref: uniprot C3XPR5 825
xref: PTHR12027:SF101
organism: Branchiostoma floridae

Cadherin-23
type: ProteinReference
xref: PTHR24027:SF425
xref: uniprot Q99PF4 708
organism: Mus musculus

PTHR11937:SF201
type: RelationshipXref
id: PTHR11937:SF201
db: PANTHER Family
relationship type: By Homology

PTHR24028:SF101
type: RelationshipXref
id: PTHR24028:SF101
db: PANTHER Family
relationship type: By Homology

uniprot O60353 1021
type: UnificationXref
id: O60353
db: uniprot

uniprot F6VFP8 507
type: UnificationXref
id: F6VFP8
db: uniprot

Actin
type: ProteinReference
xref: PTHR11937:SF387
xref: uniprot P60010 307
organism: Saccharomyces cerevisiae

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A1D5RD87 4
xref: PTHR24054:SF16
organism: Macaca mulatta

uniprot Q7PT75 656
type: UnificationXref
id: Q7PT75
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF240
xref: uniprot F6XUU0 255
organism: Monodelphis domestica

Protein Wnt-7b
type: ProteinReference
xref: uniprot Q3L254 944
xref: PTHR12027:SF73
organism: Gallus gallus

Receptor tyrosine-protein kinase erbB-4
type: ProteinReference
xref: PTHR24416:SF90
xref: uniprot Q62956 144
organism: Rattus norvegicus

Tyrosine-protein kinase FRK
type: ProteinReference
xref: uniprot P42685 95
organism: Homo sapiens

uniprot E2RC09 86
type: UnificationXref
id: E2RC09
db: uniprot

ncbitaxon 39947 176
type: UnificationXref
id: 39947
db: ncbitaxon

Cadherin-22
type: ProteinReference
xref: PTHR24027:SF311
xref: uniprot Q9UJ99 728
organism: Homo sapiens

Receptor protein-tyrosine kinase
type: ProteinReference
xref: PTHR24416:SF90
xref: uniprot F1P258 125
organism: Gallus gallus

uniprot Q60GF6 947
type: UnificationXref
id: Q60GF6
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A1D5QQ23 120
xref: PTHR24416:SF88
organism: Macaca mulatta

PTHR24028:SF134
type: RelationshipXref
id: PTHR24028:SF134
db: PANTHER Family
relationship type: By Homology

PTHR24028:SF133
type: RelationshipXref
id: PTHR24028:SF133
db: PANTHER Family
relationship type: By Homology

uniprot P61160 314
type: UnificationXref
id: P61160
db: uniprot

Protocadherin-15
type: ProteinReference
xref: uniprot Q96QU1 707
xref: PTHR24028:SF11
organism: Homo sapiens

Protein Wnt
type: ProteinReference
xref: uniprot C3ZCG7 830
xref: PTHR12027:SF102
organism: Branchiostoma floridae

uniprot P02572 278
type: UnificationXref
id: P02572
db: uniprot

uniprot Q562R1 351
type: UnificationXref
id: Q562R1
db: uniprot

Actin, alpha cardiac muscle 1
type: ProteinReference
xref: PTHR11937:SF176
xref: uniprot Q6P640 368
organism: Xenopus tropicalis

HETERODIMER_ASSOCIATION_LEFT__Cadherin-_Complex__betacatenin_alphacatenin__F_actin_-RIGHT__Complex__Cadherin_betacatenin__alphacatenin_F_actin_-_r42
type: ComplexAssembly
spontaneous: true
conversion direction: LEFT_TO_RIGHT
xref: HETERODIMER ASSOCIATION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r42 1182
participant stoichiometry: PARTICIPANT STOICHIOMETRY r42 1181
participant stoichiometry: PARTICIPANT STOICHIOMETRY r42 1180
left: Cadherin
left: Complex (betacatenin/alphacatenin/ F-actin)
interaction type: HETERODIMER_ASSOCIATION
right: Complex (Cadherin/betacatenin/ alphacatenin/F-actin)

PTHR24028:SF139
type: RelationshipXref
id: PTHR24028:SF139
db: PANTHER Family
relationship type: By Homology

Frizzled class receptor 4
type: ProteinReference
xref: uniprot E2RIL8 988
xref: PTHR11309:SF23
organism: Canis lupus familiaris

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF33
xref: uniprot E1BDG5 840
organism: Bos taurus

Os05g0106600 protein
type: ProteinReference
xref: PTHR11937:SF464
xref: uniprot Q65XH8 361
organism: Oryza sativa

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF91
xref: uniprot A0A2J8LQ70 814
organism: Pan troglodytes

uniprot C3ZHN2 224
type: UnificationXref
id: C3ZHN2
db: uniprot

uniprot P20417 790
type: UnificationXref
id: P20417
db: uniprot

Casein kinase 2 alpha 2
type: ProteinReference
xref: PTHR24054:SF34
xref: uniprot F6RN85 29
organism: Xenopus tropicalis

Lymphoid enhancer-binding factor 1
type: ProteinReference
xref: uniprot Q9QXN1 115
xref: PTHR10373:SF11
organism: Rattus norvegicus

uniprot F1MEC8 478
type: UnificationXref
id: F1MEC8
db: uniprot

ncbitaxon 418459 231
type: UnificationXref
id: 418459
db: ncbitaxon

uniprot P55285 604
type: UnificationXref
id: P55285
db: uniprot

uniprot F2Z4N0 243
type: UnificationXref
id: F2Z4N0
db: uniprot

uniprot O60245 580
type: UnificationXref
id: O60245
db: uniprot

PTHR24028:SF124
type: RelationshipXref
id: PTHR24028:SF124
db: PANTHER Family
relationship type: By Homology

PTHR11309:SF126
type: RelationshipXref
id: PTHR11309:SF126
db: PANTHER Family
relationship type: By Homology

uniprot Q8RYC2 384
type: UnificationXref
id: Q8RYC2
db: uniprot

uniprot Q9IA05 1048
type: UnificationXref
id: Q9IA05
db: uniprot

Protein Wnt
type: ProteinReference
xref: uniprot F1N4C0 850
xref: PTHR12027:SF7
organism: Bos taurus

uniprot B0S5E7 981
type: UnificationXref
id: B0S5E7
db: uniprot

betacatenin
type: Protein
entity reference: betacatenin
feature: Y142 betacatenin s111 a157 rs2
feature: betacatenin s111 a157 rs5
feature: T112 betacatenin s111 a157 rs3
feature: Y654 betacatenin s111 a157 rs1
feature: S betacatenin s111 a157 rs4
cellular location: nucleus
comment: SPECIES_TYPE=PROTEIN

PTHR24028:SF128
type: RelationshipXref
id: PTHR24028:SF128
db: PANTHER Family
relationship type: By Homology

Cadherin-7
type: ProteinReference
xref: uniprot Q9ULB5 730
xref: PTHR24027:SF91
organism: Homo sapiens

uniprot Q2QLE7 943
type: UnificationXref
id: Q2QLE7
db: uniprot

Cadherin-9
type: ProteinReference
xref: PTHR24027:SF99
xref: uniprot Q9ULB4 729
organism: Homo sapiens

uniprot F6ZZG9 257
type: UnificationXref
id: F6ZZG9
db: uniprot

uniprot Q6TYS2 370
type: UnificationXref
id: Q6TYS2
db: uniprot

Protein Wnt
type: ProteinReference
xref: uniprot F6SF10 856
xref: PTHR12027:SF75
organism: Monodelphis domestica

Tyrosine-protein kinase
type: ProteinReference
xref: uniprot F7FG65 90
xref: PTHR24418:SF44
organism: Monodelphis domestica

Actin-related protein 2
type: ProteinReference
xref: PTHR11937:SF37
xref: uniprot P61161 315
organism: Mus musculus

Actin
type: ProteinReference
xref: uniprot Q9U1E8 387
xref: PTHR11937:SF387
organism: Leishmania major

uniprot H2QQ62 566
type: UnificationXref
id: H2QQ62
db: uniprot

Tyrosine-protein kinase
type: ProteinReference
xref: uniprot F7G2C9 91
organism: Macaca mulatta

Actin-related protein 2
type: ProteinReference
xref: uniprot P61160 314
xref: PTHR11937:SF409
organism: Homo sapiens

Protein wingless
type: ProteinReference
xref: PTHR12027:SF91
xref: uniprot P09615 905
organism: Drosophila melanogaster

Catenin delta 1
type: ProteinReference
xref: uniprot A0A2I3TBC2 793
organism: Pan troglodytes

Tyrosine-protein kinase
type: ProteinReference
xref: uniprot F7BV42 1068
organism: Macaca mulatta

Pan troglodytes
type: BioSource
xref: ncbitaxon 9598 9

uniprot P09544 904
type: UnificationXref
id: P09544
db: uniprot

uniprot P10989 291
type: UnificationXref
id: P10989
db: uniprot

Actin, alpha 2, smooth muscle, aorta
type: ProteinReference
xref: uniprot Q5M8T9 358
xref: PTHR11937:SF445
organism: Xenopus tropicalis

uniprot Q9WUD6 968
type: UnificationXref
id: Q9WUD6
db: uniprot

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF70
xref: uniprot D4A3K6 836
organism: Rattus norvegicus

ncbitaxon 5759 204
type: UnificationXref
id: 5759
db: ncbitaxon

uniprot Q9NYQ7 722
type: UnificationXref
id: Q9NYQ7
db: uniprot

uniprot Q07014 1076
type: UnificationXref
id: Q07014
db: uniprot

Catenin delta-2
type: ProteinReference
xref: uniprot O35927 801
organism: Mus musculus

Cadherin 3
type: ProteinReference
xref: PTHR24027:SF267
xref: uniprot F1LMI3 467
organism: Rattus norvegicus

uniprot A0A1D5REM7 99
type: UnificationXref
id: A0A1D5REM7
db: uniprot

Protocadherin Fat 2
type: ProteinReference
xref: uniprot O88277 583
xref: PTHR24026:SF37
organism: Rattus norvegicus

Actin-2
type: ProteinReference
xref: PTHR11937:SF410
xref: uniprot A3C6D7 175
organism: Oryza sativa

Cadherin EGF LAG seven-pass G-type receptor 3
type: ProteinReference
xref: PTHR24026:SF38
xref: uniprot O88278 584
organism: Rattus norvegicus

Wnt
type: Protein
entity reference: Wnt
comment: SPECIES_TYPE=PROTEIN

uniprot F1MCQ7 124
type: UnificationXref
id: F1MCQ7
db: uniprot

uniprot A0A1D5NX70 808
type: UnificationXref
id: A0A1D5NX70
db: uniprot

Cadherin EGF LAG seven-pass G-type receptor 1
type: ProteinReference
xref: PTHR24026:SF36
xref: uniprot O35161 578
organism: Mus musculus

ncbitaxon 10090 40
type: UnificationXref
id: 10090
db: ncbitaxon

uniprot Q9H461 1047
type: UnificationXref
id: Q9H461
db: uniprot

uniprot A8Y4R0 194
type: UnificationXref
id: A8Y4R0
db: uniprot

uniprot Q9R0M0 725
type: UnificationXref
id: Q9R0M0
db: uniprot

Frizzled class receptor 10
type: ProteinReference
xref: uniprot Q9W6E3 1059
xref: PTHR11309:SF86
organism: Danio rerio

uniprot F1RD80 490
type: UnificationXref
id: F1RD80
db: uniprot

Protein Wnt-5a
type: ProteinReference
xref: uniprot Q9QXQ7 963
xref: PTHR12027:SF33
organism: Rattus norvegicus

uniprot E7FAU6 462
type: UnificationXref
id: E7FAU6
db: uniprot

Protein Wnt-4
type: ProteinReference
xref: PTHR12027:SF101
xref: uniprot Q9QXQ5 962
organism: Rattus norvegicus

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF76
xref: uniprot A0A2J8LQ46 813
organism: Pan troglodytes

uniprot H2Q1A9 269
type: UnificationXref
id: H2Q1A9
db: uniprot

uniprot A0A2I3TJM5 419
type: UnificationXref
id: A0A2I3TJM5
db: uniprot

uniprot E1C235 452
type: UnificationXref
id: E1C235
db: uniprot

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF72
xref: uniprot F6WHM2 861
organism: Monodelphis domestica

Frizzled-9
type: ProteinReference
xref: uniprot Q9R216 1054
xref: PTHR11309:SF79
organism: Mus musculus

Cadherin-24
type: ProteinReference
xref: uniprot Q6PFX6 649
xref: PTHR24027:SF272
organism: Mus musculus

Cadherin 5
type: ProteinReference
xref: uniprot F1M7E5 474
xref: PTHR24027:SF89
organism: Rattus norvegicus

uniprot E1BQ11 796
type: UnificationXref
id: E1BQ11
db: uniprot

ncbitaxon 284811 373
type: UnificationXref
id: 284811
db: ncbitaxon

uniprot P04628 903
type: UnificationXref
id: P04628
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot C3XZ13 219
organism: Branchiostoma floridae

uniprot A0A2K6HNB9 427
type: UnificationXref
id: A0A2K6HNB9
db: uniprot

uniprot O75309 582
type: UnificationXref
id: O75309
db: uniprot

betacatenin
type: Protein
entity reference: betacatenin
feature: betacatenin s5 sa1 rs5
feature: Y654 betacatenin s5 sa1 rs1
feature: Y142 betacatenin s5 sa1 rs2
feature: COMPLEX PARTICIPANT BINDING FEATURE s5 sa1 1121
feature: S betacatenin s5 sa1 rs4
feature: T112 betacatenin s5 sa1 rs3
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

uniprot P53494 304
type: UnificationXref
id: P53494
db: uniprot

Protein Wnt
type: ProteinReference
xref: uniprot F6XUZ7 865
xref: PTHR12027:SF87
organism: Monodelphis domestica

uniprot Q91XU7 687
type: UnificationXref
id: Q91XU7
db: uniprot

uniprot P07830 283
type: UnificationXref
id: P07830
db: uniprot

Wnt s26 sa20 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Wnt
stoichiometric coefficient: 1.0

Tyrosine-protein kinase Lyn
type: ProteinReference
xref: uniprot P25911 1074
organism: Mus musculus

Casein kinase II subunit beta
type: ProteinReference
xref: PTHR11740:SF0
xref: uniprot P08182 44
organism: Drosophila melanogaster

uniprot Q7SXW6 376
type: UnificationXref
id: Q7SXW6
db: uniprot

Cadherin 11
type: ProteinReference
xref: PTHR24027:SF85
xref: uniprot F1P6U6 484
organism: Canis lupus familiaris

Receptor protein-tyrosine kinase
type: ProteinReference
xref: uniprot K7DJM0 130
xref: PTHR24416:SF137
organism: Pan troglodytes

uniprot G5EDK5 560
type: UnificationXref
id: G5EDK5
db: uniprot

Y142 betacatenin s93 a132 rs2
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y142
feature location: Y142 betacatenin s93 a132 rs2 Y142
comment: MODIFICATION_RESIDUE_NAME=Y142
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=2.893781136851091

Casein kinase II subunit alpha
type: ProteinReference
xref: uniprot P08181 43
xref: PTHR24054:SF0
organism: Drosophila melanogaster

uniprot F7E6Z1 534
type: UnificationXref
id: F7E6Z1
db: uniprot

uniprot A0A3Q1MCN6 432
type: UnificationXref
id: A0A3Q1MCN6
db: uniprot

uniprot F1P6U6 484
type: UnificationXref
id: F1P6U6
db: uniprot

Protein mom-5
type: ProteinReference
xref: PTHR11309:SF47
xref: uniprot A0A0K3AWM6 972
organism: Caenorhabditis elegans

Cadherin 10
type: ProteinReference
xref: uniprot F1LR98 468
xref: PTHR24027:SF290
organism: Rattus norvegicus

uniprot W4ZD41 393
type: UnificationXref
id: W4ZD41
db: uniprot

CSNK2A1 isoform 3
type: ProteinReference
xref: PTHR24054:SF16
xref: uniprot K7D8P4 38
organism: Pan troglodytes

Cadherin 24
type: ProteinReference
xref: uniprot E1BQ10 451
xref: PTHR24027:SF272
organism: Bos taurus

PARTICIPANT STOICHIOMETRY r23 1192
type: Stoichiometry
physical entity: a133_degraded
stoichiometric coefficient: 1.0

Uncharacterized protein
type: ProteinReference
xref: uniprot E1BQ11 796
organism: Bos taurus

uniprot Q91Y04 699
type: UnificationXref
id: Q91Y04
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F6W1H1 508
xref: PTHR24028:SF260
organism: Macaca mulatta

PARTICIPANT STOICHIOMETRY r23 1191
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

uniprot F7GUD3 157
type: UnificationXref
id: F7GUD3
db: uniprot

T112 betacatenin s5 sa1 rs3
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY T112
feature location: T112 betacatenin s5 sa1 rs3 T112
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=T112
comment: MODIFICATION_RESIDUE_ANGLE=-0.0

AGAP002310-PA
type: ProteinReference
xref: uniprot Q7PR41 655
xref: PTHR24026:SF93
organism: Anopheles gambiae

uniprot F6PKK7 88
type: UnificationXref
id: F6PKK7
db: uniprot

uniprot A0A2J8NDG6 425
type: UnificationXref
id: A0A2J8NDG6
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF192
xref: uniprot F7ALP1 259
organism: Monodelphis domestica

Receptor protein-tyrosine kinase
type: ProteinReference
xref: uniprot G3V6K6 129
xref: PTHR24416:SF91
organism: Rattus norvegicus

Protocadherin Fat 3
type: ProteinReference
xref: uniprot Q8R508 674
xref: PTHR24026:SF49
organism: Rattus norvegicus

uniprot F7FZG1 539
type: UnificationXref
id: F7FZG1
db: uniprot

CDH4 isoform 1
type: ProteinReference
xref: PTHR24027:SF81
xref: uniprot H2QKP9 565
organism: Pan troglodytes

uniprot P68133 331
type: UnificationXref
id: P68133
db: uniprot

HETERODIMER_ASSOCIATION_LEFT__betacatenin-_Tyrosine_phosphatases-_P120-RIGHT__Complex__betacatenin_Tyrosine_phosphatases__P120_-_r54
type: ComplexAssembly
spontaneous: true
conversion direction: LEFT_TO_RIGHT
xref: HETERODIMER ASSOCIATION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r54 1190
participant stoichiometry: PARTICIPANT STOICHIOMETRY r54 1187
participant stoichiometry: PARTICIPANT STOICHIOMETRY r54 1189
participant stoichiometry: PARTICIPANT STOICHIOMETRY r54 1188
left: P120
left: betacatenin
left: Tyrosine phosphatases
interaction type: HETERODIMER_ASSOCIATION
right: Complex (betacatenin/Tyrosine phosphatases/ P120)

Frizzled class receptor 3
type: ProteinReference
xref: uniprot E2R9M9 986
xref: PTHR11309:SF22
organism: Canis lupus familiaris

Protein Wnt-2
type: ProteinReference
xref: uniprot Q2QLE7 943
xref: PTHR12027:SF86
organism: Pan troglodytes

uniprot A6H6X8 819
type: UnificationXref
id: A6H6X8
db: uniprot

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF84
xref: uniprot A0A3Q1M1A0 815
organism: Bos taurus

Protein Wnt-8c
type: ProteinReference
xref: uniprot P51030 930
xref: PTHR12027:SF92
organism: Gallus gallus

Protocadherin 12
type: ProteinReference
xref: uniprot F1MA46 475
xref: PTHR24028:SF42
organism: Rattus norvegicus

Frizzled class receptor 6
type: ProteinReference
xref: PTHR11309:SF75
xref: uniprot G3V6L1 1010
organism: Rattus norvegicus

Macaca mulatta
type: BioSource
xref: ncbitaxon 9544 5

ncbitaxon 7668 83
type: UnificationXref
id: 7668
db: ncbitaxon

T112 betacatenin s111 a157 rs3
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY T112
feature location: T112 betacatenin s111 a157 rs3 T112
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=T112
comment: MODIFICATION_RESIDUE_ANGLE=-0.0

uniprot O00744 894
type: UnificationXref
id: O00744
db: uniprot

uniprot A0A1D5QHG9 404
type: UnificationXref
id: A0A1D5QHG9
db: uniprot

uniprot C3XYC8 216
type: UnificationXref
id: C3XYC8
db: uniprot

uniprot F7GAV2 128
type: UnificationXref
id: F7GAV2
db: uniprot

Proto-oncogene Wnt-1
type: ProteinReference
xref: PTHR12027:SF91
xref: uniprot P04628 903
organism: Homo sapiens

Protein Wnt-8b
type: ProteinReference
xref: PTHR12027:SF94
xref: uniprot P51029 929
organism: Danio rerio

Uncharacterized protein
type: ProteinReference
xref: PTHR24027:SF89
xref: uniprot F7DX07 532
organism: Macaca mulatta

uniprot F7AAP1 519
type: UnificationXref
id: F7AAP1
db: uniprot

Protein Wnt-8a
type: ProteinReference
xref: PTHR12027:SF92
xref: uniprot P51028 928
organism: Danio rerio

P120 s110 a156 rs1
type: ModificationFeature
modification type: phosphorylated residue
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=
comment: MODIFICATION_RESIDUE_ANGLE=3.14

Actin-1
type: ProteinReference
xref: uniprot Q8I4X0 381
xref: PTHR11937:SF387
organism: Plasmodium falciparum

Uncharacterized protein
type: ProteinReference
xref: uniprot E1C235 452
xref: PTHR24027:SF96
organism: Gallus gallus

uniprot Q8CDY9 669
type: UnificationXref
id: Q8CDY9
db: uniprot

PTHR24027:SF106
type: RelationshipXref
id: PTHR24027:SF106
db: PANTHER Family
relationship type: By Homology

Actin-1
type: ProteinReference
xref: PTHR11937:SF469
xref: uniprot Q10DV7 344
organism: Oryza sativa

uniprot H2R1Q6 576
type: UnificationXref
id: H2R1Q6
db: uniprot

Cadherin-2
type: ProteinReference
xref: PTHR24027:SF79
xref: uniprot P15116 591
organism: Mus musculus

Casein kinase II
type: Protein
entity reference: Casein kinase II
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

uniprot P09803 587
type: UnificationXref
id: P09803
db: uniprot

uniprot P22223 594
type: UnificationXref
id: P22223
db: uniprot

Wnt inhibitor of Dorsal protein
type: ProteinReference
xref: PTHR12027:SF81
xref: uniprot Q9VFX1 967
organism: Drosophila melanogaster

S T Cadherin s12 sa4 rs2
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY S T
feature location: S T Cadherin s12 sa4 rs2 S T
comment: MODIFICATION_RESIDUE_NAME=S/T
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=0.09

uniprot H2Q7M1 561
type: UnificationXref
id: H2Q7M1
db: uniprot

Y654 betacatenin s20 sa14 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y654
feature location: Y654 betacatenin s20 sa14 rs1 Y654
comment: MODIFICATION_RESIDUE_ANGLE=3.3479165476195107
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=Y654

uniprot F1RDG9 87
type: UnificationXref
id: F1RDG9
db: uniprot

uniprot F1Q334 104
type: UnificationXref
id: F1Q334
db: uniprot

Protocadherin alpha-4
type: ProteinReference
xref: uniprot O88689 585
xref: PTHR24028:SF82
organism: Mus musculus

uniprot P63261 322
type: UnificationXref
id: P63261
db: uniprot

uniprot Q7QDV6 1040
type: UnificationXref
id: Q7QDV6
db: uniprot

betacatenin
type: Protein
entity reference: betacatenin
feature: T112 betacatenin s30 sa17 rs3
feature: Y654 betacatenin s30 sa17 rs1
feature: S betacatenin s30 sa17 rs4
feature: COMPLEX PARTICIPANT BINDING FEATURE s30 sa17 1095
feature: betacatenin s30 sa17 rs5
feature: Y142 betacatenin s30 sa17 rs2
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

Uncharacterized protein
type: ProteinReference
xref: uniprot F1N4K7 992
xref: PTHR11309:SF31
organism: Bos taurus

uniprot P83967 338
type: UnificationXref
id: P83967
db: uniprot

Tyrosine-protein kinase
type: ProteinReference
xref: uniprot H2QTL3 92
organism: Pan troglodytes

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF75
xref: uniprot D3ZF63 832
organism: Rattus norvegicus

Tyrosine-protein kinase
type: ProteinReference
xref: uniprot E2RC09 86
xref: PTHR24418:SF44
organism: Canis lupus familiaris

uniprot P55287 606
type: UnificationXref
id: P55287
db: uniprot

uniprot E2QX22 453
type: UnificationXref
id: E2QX22
db: uniprot

Protocadherin-12
type: ProteinReference
xref: uniprot Q9NPG4 719
xref: PTHR24028:SF42
organism: Homo sapiens

Uncharacterized protein
type: ProteinReference
xref: uniprot F7CBX9 527
xref: PTHR24027:SF91
organism: Monodelphis domestica

uniprot Q8BNA6 668
type: UnificationXref
id: Q8BNA6
db: uniprot

uniprot D4A497 441
type: UnificationXref
id: D4A497
db: uniprot

Puccinia graminis
type: BioSource
xref: ncbitaxon 418459 231

Protocadherin 9
type: ProteinReference
xref: PTHR24028:SF248
xref: uniprot F7BUJ8 524
organism: Xenopus tropicalis

PTHR24025:SF18
type: RelationshipXref
id: PTHR24025:SF18
db: PANTHER Family
relationship type: By Homology

PTHR24025:SF17
type: RelationshipXref
id: PTHR24025:SF17
db: PANTHER Family
relationship type: By Homology

uniprot Q7PUW9 657
type: UnificationXref
id: Q7PUW9
db: uniprot

uniprot Q7PPU8 653
type: UnificationXref
id: Q7PPU8
db: uniprot

uniprot F6XUU0 255
type: UnificationXref
id: F6XUU0
db: uniprot

uniprot H2Q772 1012
type: UnificationXref
id: H2Q772
db: uniprot

uniprot A4ZGP0 818
type: UnificationXref
id: A4ZGP0
db: uniprot

Actin
type: ProteinReference
xref: uniprot P90623 340
xref: PTHR11937:SF387
organism: Trichomonas vaginalis

uniprot F1RCB6 242
type: UnificationXref
id: F1RCB6
db: uniprot

CSNK2A2 isoform 1
type: ProteinReference
xref: uniprot K7CVS9 37
xref: PTHR24054:SF34
organism: Pan troglodytes

STATE_TRANSITION
type: RelationshipTypeVocabulary

uniprot A7MB15 979
type: UnificationXref
id: A7MB15
db: uniprot

uniprot F1N4C0 850
type: UnificationXref
id: F1N4C0
db: uniprot

Cadherin-2 preproprotein
type: ProteinReference
xref: uniprot F6WI86 510
xref: PTHR24027:SF79
organism: Macaca mulatta

Uncharacterized protein
type: ProteinReference
xref: uniprot F7F965 800
organism: Macaca mulatta

uniprot H9ENR6 36
type: UnificationXref
id: H9ENR6
db: uniprot

Frizzled-3
type: ProteinReference
xref: PTHR11309:SF22
xref: uniprot Q9NPG1 1051
organism: Homo sapiens

Chlamydomonas reinhardtii
type: BioSource
xref: ncbitaxon 3055 188

uniprot P63270 326
type: UnificationXref
id: P63270
db: uniprot

uniprot P62739 318
type: UnificationXref
id: P62739
db: uniprot

Y654 betacatenin s112 a160 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y654
feature location: Y654 betacatenin s112 a160 rs1 Y654
comment: MODIFICATION_RESIDUE_ANGLE=3.3479165476195107
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=Y654

uniprot Q4JLT0 945
type: UnificationXref
id: Q4JLT0
db: uniprot

Protein Wnt (Fragment)
type: ProteinReference
xref: PTHR12027:SF81
xref: uniprot C3XYW6 826
organism: Branchiostoma floridae

uniprot Q9UVF3 389
type: UnificationXref
id: Q9UVF3
db: uniprot

Actin-10
type: ProteinReference
xref: PTHR11937:SF421
xref: uniprot Q54GX7 348
organism: Dictyostelium discoideum

PTHR24025:SF23
type: RelationshipXref
id: PTHR24025:SF23
db: PANTHER Family
relationship type: By Homology

Protein Wnt
type: ProteinReference
xref: uniprot E2QXQ3 843
xref: PTHR12027:SF7
organism: Canis lupus familiaris

F-actin
type: Protein
entity reference: F-actin
feature: COMPLEX PARTICIPANT BINDING FEATURE s4 sa7 1103
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

uniprot Q8R490 673
type: UnificationXref
id: Q8R490
db: uniprot

uniprot F1PVD5 489
type: UnificationXref
id: F1PVD5
db: uniprot

Catenin beta-1
type: ProteinReference
xref: uniprot Q02248 78
xref: PTHR45976:SF4
organism: Mus musculus

uniprot O35161 578
type: UnificationXref
id: O35161
db: uniprot

uniprot A6QR62 123
type: UnificationXref
id: A6QR62
db: uniprot

Major actin
type: ProteinReference
xref: uniprot P07830 283
xref: PTHR11937:SF387
organism: Dictyostelium discoideum

uniprot Q55EU6 350
type: UnificationXref
id: Q55EU6
db: uniprot

Protein Wnt-2b
type: ProteinReference
xref: uniprot O70283 899
xref: PTHR12027:SF93
organism: Mus musculus

Receptor tyrosine-protein kinase erbB-2
type: ProteinReference
xref: uniprot P04626 134
xref: PTHR24416:SF137
organism: Homo sapiens

Protein Wnt
type: ProteinReference
xref: uniprot A0A1D5NX70 808
xref: PTHR12027:SF93
organism: Gallus gallus

uniprot Q9Y5F7 759
type: UnificationXref
id: Q9Y5F7
db: uniprot

CDH13 isoform 2
type: ProteinReference
xref: PTHR24027:SF80
xref: uniprot H2QBL4 564
organism: Pan troglodytes

Y142 betacatenin s20 sa14 rs2
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y142
feature location: Y142 betacatenin s20 sa14 rs2 Y142
comment: MODIFICATION_RESIDUE_NAME=Y142
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=2.893781136851091

uniprot F6SV99 1000
type: UnificationXref
id: F6SV99
db: uniprot

Caenorhabditis briggsae
type: BioSource
xref: ncbitaxon 6238 13

Caenorhabditis elegans
type: BioSource
xref: ncbitaxon 6239 46

Actin-3
type: ProteinReference
xref: uniprot P07829 282
xref: PTHR11937:SF421
organism: Dictyostelium discoideum

uniprot P18334 45
type: UnificationXref
id: P18334
db: uniprot

Actin-18
type: ProteinReference
xref: uniprot P07828 280
xref: PTHR11937:SF421
organism: Dictyostelium discoideum

Pristionchus pacificus
type: BioSource
xref: ncbitaxon 54126 168

uniprot F7E9X7 799
type: UnificationXref
id: F7E9X7
db: uniprot

uniprot D3ZFS0 833
type: UnificationXref
id: D3ZFS0
db: uniprot

uniprot Q9Y5F0 754
type: UnificationXref
id: Q9Y5F0
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF176
xref: uniprot F7GL73 266
organism: Monodelphis domestica

uniprot P60010 307
type: UnificationXref
id: P60010
db: uniprot

uniprot A0A3Q1NJC6 794
type: UnificationXref
id: A0A3Q1NJC6
db: uniprot

Receptor tyrosine-protein kinase erbB-4
type: ProteinReference
xref: PTHR24416:SF90
xref: uniprot Q15303 140
organism: Homo sapiens

uniprot Q8T3S5 65
type: UnificationXref
id: Q8T3S5
db: uniprot

Cadherin 6, type 2, K-cadherin (Fetal kidney)
type: ProteinReference
xref: uniprot H2R1Q6 576
xref: PTHR24027:SF322
organism: Pan troglodytes

uniprot Q99PF4 708
type: UnificationXref
id: Q99PF4
db: uniprot

uniprot P55284 603
type: UnificationXref
id: P55284
db: uniprot

Actin, alpha 2, smooth muscle, aorta
type: ProteinReference
xref: uniprot F7F4W9 265
xref: PTHR11937:SF201
organism: Ornithorhynchus anatinus

uniprot Q9UBV4 966
type: UnificationXref
id: Q9UBV4
db: uniprot

Predicted protein
type: ProteinReference
xref: PTHR11937:SF387
xref: uniprot A7SCN8 182
organism: Nematostella vectensis

uniprot F6SF10 856
type: UnificationXref
id: F6SF10
db: uniprot

Casein kinase II subunit alpha'
type: ProteinReference
xref: uniprot P19784 48
xref: PTHR24054:SF34
organism: Homo sapiens

uniprot Q9Y5I2 780
type: UnificationXref
id: Q9Y5I2
db: uniprot

uniprot Q9H1J7 960
type: UnificationXref
id: Q9H1J7
db: uniprot

Protein Wnt
type: ProteinReference
xref: uniprot H2Q569 884
xref: PTHR12027:SF87
organism: Pan troglodytes

uniprot A8WWU4 980
type: UnificationXref
id: A8WWU4
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot C3XYC6 214
xref: PTHR11937:SF468
organism: Branchiostoma floridae

ncbitaxon 36329 382
type: UnificationXref
id: 36329
db: ncbitaxon

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF468
xref: uniprot C3XYC5 213
organism: Branchiostoma floridae

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF468
xref: uniprot C3XYC8 216
organism: Branchiostoma floridae

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF468
xref: uniprot C3XYC7 215
organism: Branchiostoma floridae

Uncharacterized protein
type: ProteinReference
xref: uniprot C3XYC2 210
xref: PTHR11937:SF468
organism: Branchiostoma floridae

uniprot P10288 589
type: UnificationXref
id: P10288
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF468
xref: uniprot C3XYC4 212
organism: Branchiostoma floridae

Uncharacterized protein
type: ProteinReference
xref: uniprot C3XYC3 211
xref: PTHR11937:SF468
organism: Branchiostoma floridae

uniprot F7F9Q9 34
type: UnificationXref
id: F7F9Q9
db: uniprot

Actin, alpha 1, skeletal muscle
type: ProteinReference
xref: PTHR11937:SF193
xref: uniprot Q6DIV8 364
organism: Xenopus tropicalis

Protein Wnt-2
type: ProteinReference
xref: PTHR12027:SF86
xref: uniprot A4D7S0 817
organism: Bos taurus

Y654 betacatenin s93 a132 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y654
feature location: Y654 betacatenin s93 a132 rs1 Y654
comment: MODIFICATION_RESIDUE_ANGLE=3.3479165476195107
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=Y654

alphacatenin s2 sa6 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: alphacatenin
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r46 1169
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

uniprot F7GUW1 545
type: UnificationXref
id: F7GUW1
db: uniprot

PARTICIPANT STOICHIOMETRY r46 1168
type: Stoichiometry
physical entity: Complex (betacatenin/alphacatenin/ F-actin)
stoichiometric coefficient: 1.0

DISSOCIATION_LEFT__Complex__betacatenin_alphacatenin__F_actin_-RIGHT__betacatenin-_F_actin-_alphacatenin-_r46
type: ComplexAssembly
spontaneous: false
conversion direction: LEFT_TO_RIGHT
xref: DISSOCIATION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r46 1168
participant stoichiometry: PARTICIPANT STOICHIOMETRY r46 1171
participant stoichiometry: PARTICIPANT STOICHIOMETRY r46 1170
participant stoichiometry: PARTICIPANT STOICHIOMETRY r46 1169
left: Complex (betacatenin/alphacatenin/ F-actin)
interaction type: DISSOCIATION
right: F-actin
right: alphacatenin
right: betacatenin

Frizzled-5
type: ProteinReference
xref: uniprot Q13467 1028
xref: PTHR11309:SF136
organism: Homo sapiens

Casein kinase 2 alpha 2
type: ProteinReference
xref: PTHR24054:SF34
xref: uniprot F7F9Q9 34
organism: Ornithorhynchus anatinus

Cryptococcus neoformans
type: BioSource
xref: ncbitaxon 214684 356

Wnt
type: ProteinReference
xref: P00474
standard name: Wingless-type MMTV integration site family member
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Cadherin signaling pathway.PROTEIN.GENERIC.Wnt
comment: ENTITY_REFERENCE_NOTES=Long Name: Wnt Synonym: Synonym not specified Accession: P00474
member entity reference: Protein Wnt
member entity reference: Protein Wnt-6
member entity reference: Protein Wnt-5a
member entity reference: Protein Wnt-2b
member entity reference: Protein Wnt-7a
member entity reference: Protein Wnt-5
member entity reference: Protein Wnt-5b
member entity reference: Protein Wnt-10a
member entity reference: Protein Wnt-2
member entity reference: Protein mom-2
member entity reference: Protein Wnt-8a
member entity reference: Protein Wnt-9b
member entity reference: Protein Wnt-3a
member entity reference: Protein Wnt-11
member entity reference: Protein wingless
member entity reference: Protein Wnt-10b
member entity reference: Protein Wnt-1
member entity reference: Protein Wnt-7b
member entity reference: Protein Wnt-9a
member entity reference: Protein Wnt-4a
member entity reference: Follistatin-related protein 1
member entity reference: Protein Wnt (Fragment)
member entity reference: Wnt inhibitor of Dorsal protein

Protocadherin Fat 2
type: ProteinReference
xref: uniprot Q9NYQ8 723
xref: PTHR24026:SF37
organism: Homo sapiens

Protocadherin 19
type: ProteinReference
xref: uniprot E2REK7 459
xref: PTHR24028:SF40
organism: Canis lupus familiaris

Cadherin EGF LAG seven-pass G-type receptor 3
type: ProteinReference
xref: PTHR24026:SF38
xref: uniprot Q9NYQ7 722
organism: Homo sapiens

uniprot A0A2I3SXI2 1079
type: UnificationXref
id: A0A2I3SXI2
db: uniprot

Cadherin EGF LAG seven-pass G-type receptor 1
type: ProteinReference
xref: uniprot Q9NYQ6 721
xref: PTHR24026:SF36
organism: Homo sapiens

Glycogen synthase kinase 3 beta
type: ProteinReference
xref: PTHR24057:SF8
xref: uniprot E2RB53 1082
organism: Canis lupus familiaris

Tyrosine-protein phosphatase non-receptor type
type: ProteinReference
xref: uniprot H2R283 788
organism: Pan troglodytes

uniprot E2RSH8 148
type: UnificationXref
id: E2RSH8
db: uniprot

uniprot F7DX07 532
type: UnificationXref
id: F7DX07
db: uniprot

P120 s25 sa25 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: P120
stoichiometric coefficient: 1.0

uniprot Q9Y5E9 753
type: UnificationXref
id: Q9Y5E9
db: uniprot

uniprot Q9NYQ6 721
type: UnificationXref
id: Q9NYQ6
db: uniprot

Catenin delta-2
type: ProteinReference
xref: uniprot Q9UQB3 804
organism: Homo sapiens

uniprot D3ZFQ5 438
type: UnificationXref
id: D3ZFQ5
db: uniprot

ncbitaxon 237631 164
type: UnificationXref
id: 237631
db: ncbitaxon

uniprot F1N4K7 992
type: UnificationXref
id: F1N4K7
db: uniprot

Protocadherin-10
type: ProteinReference
xref: uniprot Q9P2E7 724
xref: PTHR24028:SF0
organism: Homo sapiens

PTHR24054:SF0
type: RelationshipXref
id: PTHR24054:SF0
db: PANTHER Family
relationship type: By Homology

MCG141285
type: ProteinReference
xref: uniprot Q91UZ8 683
xref: PTHR24028:SF58
organism: Mus musculus

uniprot P70451 161
type: UnificationXref
id: P70451
db: uniprot

Frizzled class receptor 6
type: ProteinReference
xref: uniprot F1MP23 991
xref: PTHR11309:SF75
organism: Bos taurus

Actin-2
type: ProteinReference
xref: uniprot Q96292 385
xref: PTHR11937:SF430
organism: Arabidopsis thaliana

PARTICIPANT STOICHIOMETRY r46 1171
type: Stoichiometry
physical entity: alphacatenin
stoichiometric coefficient: 1.0

Tyrosine-protein kinase
type: ProteinReference
xref: uniprot F6S8L5 89
xref: PTHR24418:SF44
organism: Xenopus tropicalis

PARTICIPANT STOICHIOMETRY r46 1170
type: Stoichiometry
physical entity: F-actin
stoichiometric coefficient: 1.0

ncbitaxon 81824 202
type: UnificationXref
id: 81824
db: ncbitaxon

betacatenin
type: Protein
entity reference: betacatenin
feature: betacatenin s13 sa5 rs5
feature: Y142 betacatenin s13 sa5 rs2
feature: T112 betacatenin s13 sa5 rs3
feature: S betacatenin s13 sa5 rs4
feature: Y654 betacatenin s13 sa5 rs1
feature: COMPLEX PARTICIPANT BINDING FEATURE s13 sa5 1107
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

uniprot Q9UJU2 116
type: UnificationXref
id: Q9UJU2
db: uniprot

uniprot F7HA59 548
type: UnificationXref
id: F7HA59
db: uniprot

Actin 1
type: ProteinReference
xref: uniprot Q6TYS2 370
xref: PTHR11937:SF387
organism: Physcomitrella patens

Branchiostoma floridae
type: BioSource
xref: ncbitaxon 7739 19

Actin, cytoplasmic 2
type: ProteinReference
xref: PTHR11937:SF414
xref: uniprot Q5ZMQ2 360
organism: Gallus gallus

Cadherin 2
type: ProteinReference
xref: uniprot A0A2I3TU99 420
xref: PTHR24027:SF79
organism: Pan troglodytes

uniprot Q5BL41 353
type: UnificationXref
id: Q5BL41
db: uniprot

uniprot H2QJF8 886
type: UnificationXref
id: H2QJF8
db: uniprot

Actin
type: ProteinReference
xref: uniprot A8JAV1 187
xref: PTHR11937:SF387
organism: Chlamydomonas reinhardtii

uniprot A0A2J8ND39 424
type: UnificationXref
id: A0A2J8ND39
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR24027:SF99
xref: uniprot F6UBJ7 498
organism: Monodelphis domestica

Tyrosine-protein phosphatase non-receptor type 1
type: ProteinReference
xref: uniprot P20417 790
organism: Rattus norvegicus

AGAP007924-PA (Fragment)
type: ProteinReference
xref: PTHR24026:SF76
xref: uniprot Q7Q3K5 661
organism: Anopheles gambiae

Glycogen synthase kinase-3 beta isoform 1
type: ProteinReference
xref: PTHR24057:SF8
xref: uniprot H9EPM1 1085
organism: Macaca mulatta

Cadherin 15
type: ProteinReference
xref: uniprot Q75NI5 651
xref: PTHR24027:SF300
organism: Rattus norvegicus

Protein Wnt-10a
type: ProteinReference
xref: uniprot Q9GZT5 958
xref: PTHR12027:SF89
organism: Homo sapiens

PTHR24054:SF28
type: RelationshipXref
id: PTHR24054:SF28
db: PANTHER Family
relationship type: By Homology

uniprot Q91Y06 700
type: UnificationXref
id: Q91Y06
db: uniprot

PARTICIPANT STOICHIOMETRY r17 1163
type: Stoichiometry
physical entity: Complex (Cadherin/Cadherin/ betacatenin/alphacatenin/ F-actin)
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r17 1161
type: Stoichiometry
physical entity: Complex (Cadherin/betacatenin)
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r17 1162
type: Stoichiometry
physical entity: Complex (alphacatenin/F-actin)
stoichiometric coefficient: 1.0

FZD7 isoform 1
type: ProteinReference
xref: uniprot A0A2I3TGC6 975
xref: PTHR11309:SF31
organism: Pan troglodytes

uniprot F7FG65 90
type: UnificationXref
id: F7FG65
db: uniprot

FAT atypical cadherin 1
type: ProteinReference
xref: PTHR24026:SF42
xref: uniprot A0A1L1SQU7 407
organism: Mus musculus

uniprot Q9GZT5 958
type: UnificationXref
id: Q9GZT5
db: uniprot

uniprot Q9VW71 744
type: UnificationXref
id: Q9VW71
db: uniprot

PTHR24028:SF98
type: RelationshipXref
id: PTHR24028:SF98
db: PANTHER Family
relationship type: By Homology

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF93
xref: uniprot F6XMD3 864
organism: Xenopus tropicalis

PTHR24028:SF95
type: RelationshipXref
id: PTHR24028:SF95
db: PANTHER Family
relationship type: By Homology

Uncharacterized protein
type: ProteinReference
xref: uniprot C3XYD4 218
organism: Branchiostoma floridae

uniprot P51029 929
type: UnificationXref
id: P51029
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot C3XYD3 217
organism: Branchiostoma floridae

PTHR24028:SF97
type: RelationshipXref
id: PTHR24028:SF97
db: PANTHER Family
relationship type: By Homology

PTHR24028:SF90
type: RelationshipXref
id: PTHR24028:SF90
db: PANTHER Family
relationship type: By Homology

PCDH10 isoform 2
type: ProteinReference
xref: uniprot H2QQ62 566
xref: PTHR24028:SF0
organism: Pan troglodytes

PTHR24028:SF91
type: RelationshipXref
id: PTHR24028:SF91
db: PANTHER Family
relationship type: By Homology

Cadherin-1
type: ProteinReference
xref: PTHR24027:SF319
xref: uniprot P12830 590
organism: Homo sapiens

PTHR24028:SF92
type: RelationshipXref
id: PTHR24028:SF92
db: PANTHER Family
relationship type: By Homology

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF88
xref: uniprot F6SXE3 858
organism: Monodelphis domestica

PTHR24028:SF93
type: RelationshipXref
id: PTHR24028:SF93
db: PANTHER Family
relationship type: By Homology

AGAP007905-PA (Fragment)
type: ProteinReference
xref: uniprot Q7Q3J3 660
organism: Anopheles gambiae

STATE_TRANSITION_LEFT__betacatenin-RIGHT__a133_degraded-_r23
type: Degradation
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r23 1192
participant stoichiometry: PARTICIPANT STOICHIOMETRY r23 1191
left: betacatenin
interaction type: STATE_TRANSITION
right: a133_degraded

uniprot Q8NEV1 64
type: UnificationXref
id: Q8NEV1
db: uniprot

uniprot C3ZCG7 830
type: UnificationXref
id: C3ZCG7
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF421
xref: uniprot F0Z796 236
organism: Dictyostelium purpureum

PTHR24054:SF34
type: RelationshipXref
id: PTHR24054:SF34
db: PANTHER Family
relationship type: By Homology

uniprot P53474 298
type: UnificationXref
id: P53474
db: uniprot

uniprot E9PVD3 463
type: UnificationXref
id: E9PVD3
db: uniprot

uniprot P55283 602
type: UnificationXref
id: P55283
db: uniprot

Ciona intestinalis
type: BioSource
xref: ncbitaxon 7719 66

Cadherin 11
type: ProteinReference
xref: PTHR24027:SF85
xref: uniprot F6XVG8 512
organism: Monodelphis domestica

betacatenin s28 sa22 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

Frizzled-4
type: ProteinReference
xref: uniprot Q9NBW1 1050
xref: PTHR11309:SF23
organism: Drosophila melanogaster

uniprot F7HPS8 551
type: UnificationXref
id: F7HPS8
db: uniprot

PTHR24028:SF87
type: RelationshipXref
id: PTHR24028:SF87
db: PANTHER Family
relationship type: By Homology

uniprot Q13634 621
type: UnificationXref
id: Q13634
db: uniprot

Protein Wnt
type: ProteinReference
xref: uniprot F7HEW6 876
xref: PTHR12027:SF78
organism: Macaca mulatta

Protocadherin 9
type: ProteinReference
xref: PTHR24028:SF248
xref: uniprot F8VPK8 553
organism: Mus musculus

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Fer-RIGHT__Fer-_r12
controller: Yes

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF91
xref: uniprot Q5TP56 946
organism: Anopheles gambiae

Actin-related protein 2
type: ProteinReference
xref: PTHR11937:SF37
xref: uniprot E2QXY7 229
organism: Canis lupus familiaris

PTHR24028:SF82
type: RelationshipXref
id: PTHR24028:SF82
db: PANTHER Family
relationship type: By Homology

PTHR24028:SF81
type: RelationshipXref
id: PTHR24028:SF81
db: PANTHER Family
relationship type: By Homology

Protein Wnt-3a
type: ProteinReference
xref: PTHR12027:SF88
xref: uniprot Q2LMP1 941
organism: Gallus gallus

GO GO:0005634 2
type: UnificationXref
id: GO:0005634
db: GO

Cadherin 18
type: ProteinReference
xref: PTHR24027:SF106
xref: uniprot E9Q9Q6 466
organism: Mus musculus

Protocadherin 10
type: ProteinReference
xref: uniprot E9PXQ7 464
xref: PTHR24028:SF0
organism: Mus musculus

PTHR24028:SF84
type: RelationshipXref
id: PTHR24028:SF84
db: PANTHER Family
relationship type: By Homology

Protein Wnt-2
type: ProteinReference
xref: uniprot Q2QL96 942
xref: PTHR12027:SF86
organism: Monodelphis domestica

PTHR24028:SF76
type: RelationshipXref
id: PTHR24028:SF76
db: PANTHER Family
relationship type: By Homology

Tyrosine-protein kinase Yes
type: ProteinReference
xref: PTHR24418:SF90
xref: uniprot F1LM93 1065
organism: Rattus norvegicus

uniprot P68399 57
type: UnificationXref
id: P68399
db: uniprot

uniprot P60710 311
type: UnificationXref
id: P60710
db: uniprot

uniprot F6VET9 505
type: UnificationXref
id: F6VET9
db: uniprot

uniprot H2QJA9 1014
type: UnificationXref
id: H2QJA9
db: uniprot

CATALYSIS
type: Catalysis
controlled: DISSOCIATION_LEFT__Complex__Cadherin_betacatenin__alphacatenin_F_actin_-RIGHT__Complex__Cadherin_betacatenin_-_Complex__alphacatenin_F_actin_-_r21
controller: EGFR

uniprot A0A3Q1MDX6 977
type: UnificationXref
id: A0A3Q1MDX6
db: uniprot

P120
type: ProteinReference
xref: P00473
standard name: Delta-catenin
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Cadherin signaling pathway.PROTEIN.GENERIC.P120
comment: ENTITY_REFERENCE_NOTES=Long Name: Delta-catenin Synonym: CAS,CTNND,Cadherin-associated Src substrate Accession: P00473
member entity reference: Catenin delta-1
member entity reference: Catenin delta 1
member entity reference: Catenin delta-2
member entity reference: Uncharacterized protein
member entity reference: Catenin delta 2
member entity reference: Catenin (Cadherin associated protein), delta 1 (Predicted), isoform CRA_a

uniprot Q9BYE9 709
type: UnificationXref
id: Q9BYE9
db: uniprot

PTHR24028:SF71
type: RelationshipXref
id: PTHR24028:SF71
db: PANTHER Family
relationship type: By Homology

PTHR24028:SF70
type: RelationshipXref
id: PTHR24028:SF70
db: PANTHER Family
relationship type: By Homology

PTHR24028:SF72
type: RelationshipXref
id: PTHR24028:SF72
db: PANTHER Family
relationship type: By Homology

ncbitaxon 8364 30
type: UnificationXref
id: 8364
db: ncbitaxon

ACTA1 isoform 1
type: ProteinReference
xref: uniprot H2Q1A9 269
xref: PTHR11937:SF193
organism: Pan troglodytes

uniprot B4F7A9 14
type: UnificationXref
id: B4F7A9
db: uniprot

PTHR24028:SF66
type: RelationshipXref
id: PTHR24028:SF66
db: PANTHER Family
relationship type: By Homology

uniprot Q9YHE8 118
type: UnificationXref
id: Q9YHE8
db: uniprot

PTHR24028:SF68
type: RelationshipXref
id: PTHR24028:SF68
db: PANTHER Family
relationship type: By Homology

uniprot F1LR98 468
type: UnificationXref
id: F1LR98
db: uniprot

PTHR24028:SF69
type: RelationshipXref
id: PTHR24028:SF69
db: PANTHER Family
relationship type: By Homology

Glycogen synthase kinase-3 beta
type: ProteinReference
xref: PTHR24057:SF8
xref: uniprot Q9WV60 1088
organism: Mus musculus

uniprot F1P802 486
type: UnificationXref
id: F1P802
db: uniprot

Cadherin-3
type: ProteinReference
xref: PTHR24027:SF267
xref: uniprot P10287 588
organism: Mus musculus

uniprot B7QIS2 16
type: UnificationXref
id: B7QIS2
db: uniprot

uniprot A0A2I3TID8 418
type: UnificationXref
id: A0A2I3TID8
db: uniprot

Tyrosine-protein kinase Fyn
type: ProteinReference
xref: uniprot A0JNB0 85
xref: PTHR24418:SF44
organism: Bos taurus

Cadherin-2
type: ProteinReference
xref: PTHR24027:SF79
xref: uniprot P10288 589
organism: Gallus gallus

uniprot F1MN70 849
type: UnificationXref
id: F1MN70
db: uniprot

Protein Wnt-2b
type: ProteinReference
xref: uniprot Q93097 955
xref: PTHR12027:SF93
organism: Homo sapiens

Cadherin 4
type: ProteinReference
xref: uniprot F1MW29 481
xref: PTHR24027:SF81
organism: Bos taurus

Protein Wnt-8b
type: ProteinReference
xref: PTHR12027:SF94
xref: uniprot Q93098 956
organism: Homo sapiens

Tyrosine-protein kinase
type: ProteinReference
xref: PTHR24418:SF53
xref: uniprot A0A2I3SIH9 146
organism: Pan troglodytes

eco ECO:0000501 658
type: UnificationXref
id: ECO:0000501
db: eco

Uncharacterized protein
type: ProteinReference
xref: uniprot F7CIV4 260
xref: PTHR11937:SF150
organism: Ornithorhynchus anatinus

Frizzled-10
type: ProteinReference
xref: uniprot Q9ULW2 1056
xref: PTHR11309:SF86
organism: Homo sapiens

uniprot Q9QXQ5 962
type: UnificationXref
id: Q9QXQ5
db: uniprot

PTHR24028:SF61
type: RelationshipXref
id: PTHR24028:SF61
db: PANTHER Family
relationship type: By Homology

Tyrosine-protein kinase Fyn
type: ProteinReference
xref: uniprot P39688 94
xref: PTHR24418:SF44
organism: Mus musculus

PTHR24028:SF60
type: RelationshipXref
id: PTHR24028:SF60
db: PANTHER Family
relationship type: By Homology

uniprot Q9U1E8 387
type: UnificationXref
id: Q9U1E8
db: uniprot

PTHR24028:SF58
type: RelationshipXref
id: PTHR24028:SF58
db: PANTHER Family
relationship type: By Homology

PTHR24028:SF56
type: RelationshipXref
id: PTHR24028:SF56
db: PANTHER Family
relationship type: By Homology

PTHR24028:SF54
type: RelationshipXref
id: PTHR24028:SF54
db: PANTHER Family
relationship type: By Homology

uniprot F1MJS2 103
type: UnificationXref
id: F1MJS2
db: uniprot

PTHR24028:SF55
type: RelationshipXref
id: PTHR24028:SF55
db: PANTHER Family
relationship type: By Homology

uniprot Q9UN74 737
type: UnificationXref
id: Q9UN74
db: uniprot

Glycogen synthase kinase-3 beta
type: ProteinReference
xref: PTHR24057:SF8
xref: uniprot P18266 1086
organism: Rattus norvegicus

Frizzled class receptor 10
type: ProteinReference
xref: uniprot Q6GL20 1037
xref: PTHR11309:SF86
organism: Xenopus tropicalis

uniprot E9GCV0 22
type: UnificationXref
id: E9GCV0
db: uniprot

uniprot O88278 584
type: UnificationXref
id: O88278
db: uniprot

Frizzled-4
type: ProteinReference
xref: PTHR11309:SF23
xref: uniprot Q9ULV1 1055
organism: Homo sapiens

Protein Wnt-10b
type: ProteinReference
xref: uniprot P48614 924
xref: PTHR12027:SF76
organism: Mus musculus

Protein Wnt-11
type: ProteinReference
xref: uniprot P48615 925
xref: PTHR12027:SF7
organism: Mus musculus

uniprot E1BQ10 451
type: UnificationXref
id: E1BQ10
db: uniprot

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF89
xref: uniprot Q60GF6 947
organism: Gallus gallus

Uncharacterized protein
type: ProteinReference
xref: PTHR24027:SF323
xref: uniprot A0A1D5QLF4 405
organism: Macaca mulatta

Cadherin 13
type: ProteinReference
xref: uniprot Q8R490 673
xref: PTHR24027:SF80
organism: Rattus norvegicus

uniprot P10287 588
type: UnificationXref
id: P10287
db: uniprot

Actin 5
type: ProteinReference
xref: uniprot A9TZ58 200
xref: PTHR11937:SF387
organism: Physcomitrella patens

uniprot Q6DHS1 363
type: UnificationXref
id: Q6DHS1
db: uniprot

Protein Wnt
type: ProteinReference
xref: uniprot C3Z2P0 829
xref: PTHR12027:SF77
organism: Branchiostoma floridae

PTHR24028:SF46
type: RelationshipXref
id: PTHR24028:SF46
db: PANTHER Family
relationship type: By Homology

Cadherin-3
type: ProteinReference
xref: PTHR24028:SF146
xref: uniprot P34616 598
organism: Caenorhabditis elegans

Actin
type: ProteinReference
xref: PTHR11937:SF387
xref: uniprot P78711 336
organism: Neurospora crassa

Uncharacterized protein
type: ProteinReference
xref: PTHR24028:SF1
xref: uniprot F6VCS5 503
organism: Macaca mulatta

Tyrosine-protein kinase
type: ProteinReference
xref: PTHR24418:SF53
xref: uniprot E1BIM8 147
organism: Bos taurus

uniprot Q9Y5F6 758
type: UnificationXref
id: Q9Y5F6
db: uniprot

uniprot F6PGQ1 1083
type: UnificationXref
id: F6PGQ1
db: uniprot

uniprot A0A2I3TS83 169
type: UnificationXref
id: A0A2I3TS83
db: uniprot

uniprot K7CY17 158
type: UnificationXref
id: K7CY17
db: uniprot

uniprot A0A2J8KIM7 421
type: UnificationXref
id: A0A2J8KIM7
db: uniprot

uniprot A3C6D7 175
type: UnificationXref
id: A3C6D7
db: uniprot

uniprot G5EDV1 1011
type: UnificationXref
id: G5EDV1
db: uniprot

Casein kinase II subunit beta
type: ProteinReference
xref: PTHR11740:SF0
xref: uniprot P67870 54
organism: Homo sapiens

Casein kinase II subunit beta
type: ProteinReference
xref: PTHR11740:SF0
xref: uniprot P67871 55
organism: Mus musculus

PTHR11740:SF0
type: RelationshipXref
id: PTHR11740:SF0
db: PANTHER Family
relationship type: By Homology

uniprot E2QVP7 985
type: UnificationXref
id: E2QVP7
db: uniprot

uniprot A3KMX5 978
type: UnificationXref
id: A3KMX5
db: uniprot

Cadherin-1
type: ProteinReference
xref: PTHR24027:SF319
xref: uniprot Q9R0T4 726
organism: Rattus norvegicus

Cadherin-22
type: ProteinReference
xref: PTHR24027:SF311
xref: uniprot Q63315 647
organism: Rattus norvegicus

Casein kinase II subunit beta
type: ProteinReference
xref: PTHR11740:SF0
xref: uniprot P67874 56
organism: Rattus norvegicus

MCG1033322
type: ProteinReference
xref: uniprot Q91V48 684
xref: PTHR24028:SF98
organism: Mus musculus

Uncharacterized protein
type: ProteinReference
xref: uniprot F6QWB7 246
xref: PTHR11937:SF477
organism: Ornithorhynchus anatinus

uniprot Q9HCL0 717
type: UnificationXref
id: Q9HCL0
db: uniprot

Tyrosine-protein kinase fyna
type: ProteinReference
xref: PTHR24418:SF44
xref: uniprot Q6EWH2 98
organism: Danio rerio

uniprot A0A2I3TMT4 1062
type: UnificationXref
id: A0A2I3TMT4
db: uniprot

CDH7 isoform 1
type: ProteinReference
xref: uniprot A0A2J8ND39 424
xref: PTHR24027:SF91
organism: Pan troglodytes

uniprot F6ZQ88 866
type: UnificationXref
id: F6ZQ88
db: uniprot

Casein kinase II subunit beta
type: ProteinReference
xref: PTHR11740:SF0
xref: uniprot P67868 53
organism: Bos taurus

ncbitaxon 9031 51
type: UnificationXref
id: 9031
db: ncbitaxon

Putative actin
type: ProteinReference
xref: uniprot A0A0D1DMT3 163
xref: PTHR11937:SF387
organism: Ustilago maydis

ncbitaxon 6669 23
type: UnificationXref
id: 6669
db: ncbitaxon

PTHR24028:SF40
type: RelationshipXref
id: PTHR24028:SF40
db: PANTHER Family
relationship type: By Homology

Protocadherin beta 20
type: ProteinReference
xref: PTHR24028:SF81
xref: uniprot D4A7P5 442
organism: Rattus norvegicus

PTHR24028:SF42
type: RelationshipXref
id: PTHR24028:SF42
db: PANTHER Family
relationship type: By Homology

PTHR24416:SF137
type: RelationshipXref
id: PTHR24416:SF137
db: PANTHER Family
relationship type: By Homology

S betacatenin s112 a160 rs4
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY S
feature location: S betacatenin s112 a160 rs4 S
comment: MODIFICATION_RESIDUE_NAME=S
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=1.6575346654708816

Cadherin 6
type: ProteinReference
xref: PTHR24027:SF322
xref: uniprot F7BE94 522
organism: Xenopus tropicalis

Frizzled 7a
type: ProteinReference
xref: PTHR11309:SF31
xref: uniprot Q8QFM3 1044
organism: Danio rerio

uniprot F7EV26 871
type: UnificationXref
id: F7EV26
db: uniprot

Protein CBR-CWN-1
type: ProteinReference
xref: PTHR12027:SF101
xref: uniprot A8X402 822
organism: Caenorhabditis briggsae

uniprot Q9BZA8 711
type: UnificationXref
id: Q9BZA8
db: uniprot

uniprot P10986 289
type: UnificationXref
id: P10986
db: uniprot

uniprot Q7PWS3 1039
type: UnificationXref
id: Q7PWS3
db: uniprot

ncbitaxon 184922 186
type: UnificationXref
id: 184922
db: ncbitaxon

Frizzled-7
type: ProteinReference
xref: PTHR11309:SF31
xref: uniprot O75084 1023
organism: Homo sapiens

uniprot P09615 905
type: UnificationXref
id: P09615
db: uniprot

Protocadherin 7
type: ProteinReference
xref: PTHR24028:SF253
xref: uniprot A0A2I3SDT1 414
organism: Pan troglodytes

uniprot B0LK22 823
type: UnificationXref
id: B0LK22
db: uniprot

Actin-42A
type: ProteinReference
xref: uniprot P02572 278
xref: PTHR11937:SF453
organism: Drosophila melanogaster

betacatenin
type: Protein
entity reference: betacatenin
feature: COMPLEX PARTICIPANT BINDING FEATURE s20 sa14 1111
feature: Y142 betacatenin s20 sa14 rs2
feature: Y654 betacatenin s20 sa14 rs1
feature: S betacatenin s20 sa14 rs4
feature: T112 betacatenin s20 sa14 rs3
feature: betacatenin s20 sa14 rs5
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

Proto-oncogene Wnt-3
type: ProteinReference
xref: PTHR12027:SF82
xref: uniprot P17553 906
organism: Mus musculus

Catenin (Cadherin-associated protein), beta 1, 88kDa
type: ProteinReference
xref: PTHR45976:SF4
xref: uniprot Q28GC2 80
organism: Xenopus tropicalis

uniprot P19139 47
type: UnificationXref
id: P19139
db: uniprot

Tyrosine-protein kinase
type: ProteinReference
xref: uniprot F7GUD3 157
xref: PTHR24418:SF227
organism: Macaca mulatta

Actin, larval muscle
type: ProteinReference
xref: uniprot P02574 279
xref: PTHR11937:SF397
organism: Drosophila melanogaster

uniprot A0A2I3SHA1 415
type: UnificationXref
id: A0A2I3SHA1
db: uniprot

uniprot E1BAM8 446
type: UnificationXref
id: E1BAM8
db: uniprot

Protein CBR-ACT-5
type: ProteinReference
xref: PTHR11937:SF359
xref: uniprot A8XS95 192
organism: Caenorhabditis briggsae

Protein Wnt-2
type: ProteinReference
xref: PTHR12027:SF86
xref: uniprot P21552 907
organism: Mus musculus

Transcription factor 7-like 1
type: ProteinReference
xref: PTHR10373:SF25
xref: uniprot Q6GL68 111
organism: Xenopus tropicalis

Fer
type: ProteinReference
xref: P00469
standard name: FPS/FES-related tyrosine kinase
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Cadherin signaling pathway.PROTEIN.GENERIC.Fer
comment: ENTITY_REFERENCE_NOTES=Long Name: FPS/FES-related tyrosine kinase Synonym: Protein tyrosine kinase 3,TYK3 Accession: P00469
member entity reference: Tyrosine-protein kinase Fer
member entity reference: Tyrosine-protein kinase

ncbitaxon 665079 178
type: UnificationXref
id: 665079
db: ncbitaxon

uniprot H2QI87 109
type: UnificationXref
id: H2QI87
db: uniprot

uniprot G3V6L1 1010
type: UnificationXref
id: G3V6L1
db: uniprot

Src
type: Protein
entity reference: Src
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

Beta-actin-like protein 2
type: ProteinReference
xref: PTHR11937:SF168
xref: uniprot Q562R1 351
organism: Homo sapiens

PTHR24028:SF11
type: RelationshipXref
id: PTHR24028:SF11
db: PANTHER Family
relationship type: By Homology

Protocadherin beta 14
type: ProteinReference
xref: PTHR24028:SF81
xref: uniprot F7CX56 528
organism: Macaca mulatta

uniprot A0A1D5RD87 4
type: UnificationXref
id: A0A1D5RD87
db: uniprot

betacatenin s112 a160 rs5
type: ModificationFeature
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=4.653633157668967
comment: MODIFICATION_RESIDUE_NAME=

PTHR24028:SF12
type: RelationshipXref
id: PTHR24028:SF12
db: PANTHER Family
relationship type: By Homology

uniprot Q14332 1029
type: UnificationXref
id: Q14332
db: uniprot

ncbitaxon 7719 66
type: UnificationXref
id: 7719
db: ncbitaxon

uniprot F6ZPQ4 256
type: UnificationXref
id: F6ZPQ4
db: uniprot

Actin
type: ProteinReference
xref: uniprot B1N2P0 203
xref: PTHR11937:SF387
organism: Entamoeba histolytica

uniprot Q08463 1026
type: UnificationXref
id: Q08463
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A3Q1MDX6 977
xref: PTHR11309:SF22
organism: Bos taurus

uniprot E2R4F0 455
type: UnificationXref
id: E2R4F0
db: uniprot

PARTICIPANT STOICHIOMETRY r39 1154
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r39 1155
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

F-actin
type: Protein
entity reference: F-actin
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

uniprot A0A3Q1LYG2 430
type: UnificationXref
id: A0A3Q1LYG2
db: uniprot

uniprot Q6P8G3 369
type: UnificationXref
id: Q6P8G3
db: uniprot

uniprot P18499 293
type: UnificationXref
id: P18499
db: uniprot

uniprot Q9Y5G3 763
type: UnificationXref
id: Q9Y5G3
db: uniprot

Protocadherin 18
type: ProteinReference
xref: uniprot F7EKI5 535
xref: PTHR24028:SF9
organism: Rattus norvegicus

PTHR11937:SF278
type: RelationshipXref
id: PTHR11937:SF278
db: PANTHER Family
relationship type: By Homology

Daphnia pulex
type: BioSource
xref: ncbitaxon 6669 23

KNOWN_TRANSITION_OMITTED_LEFT__betacatenin-RIGHT__betacatenin-_r24
type: Conversion
conversion direction: LEFT_TO_RIGHT
xref: KNOWN TRANSITION OMITTED
participant stoichiometry: PARTICIPANT STOICHIOMETRY r24 1186
participant stoichiometry: PARTICIPANT STOICHIOMETRY r24 1185
left: betacatenin
interaction type: KNOWN_TRANSITION_OMITTED
right: betacatenin

Tyrosine-protein kinase Fyn
type: ProteinReference
xref: uniprot P06241 93
xref: PTHR24418:SF44
organism: Homo sapiens

uniprot A0A2I3RYF9 122
type: UnificationXref
id: A0A2I3RYF9
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR24027:SF91
xref: uniprot F6ZW11 517
organism: Macaca mulatta

Protein Wnt
type: ProteinReference
xref: uniprot Q9I9I2 961
xref: PTHR12027:SF7
organism: Danio rerio

uniprot P70407 612
type: UnificationXref
id: P70407
db: uniprot

uniprot F6VDD4 504
type: UnificationXref
id: F6VDD4
db: uniprot

uniprot E9FRT1 232
type: UnificationXref
id: E9FRT1
db: uniprot

betacatenin s13 sa5 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

uniprot Q63315 647
type: UnificationXref
id: Q63315
db: uniprot

uniprot O75084 1023
type: UnificationXref
id: O75084
db: uniprot

Fer
type: Protein
entity reference: Fer
feature: Y Fer s7 a94 rs1
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

Cadherin-5
type: ProteinReference
xref: uniprot P33151 596
xref: PTHR24027:SF89
organism: Homo sapiens

uniprot Q9Z1Y3 785
type: UnificationXref
id: Q9Z1Y3
db: uniprot

PTHR11937:SF248
type: RelationshipXref
id: PTHR11937:SF248
db: PANTHER Family
relationship type: By Homology

Tyrosine-protein kinase
type: ProteinReference
xref: uniprot F6PKK7 88
xref: PTHR24418:SF44
organism: Macaca mulatta

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF75
xref: uniprot A0A3Q1MPF5 816
organism: Bos taurus

uniprot F1MAH6 476
type: UnificationXref
id: F1MAH6
db: uniprot

Protein Wnt
type: ProteinReference
xref: uniprot F7GH85 873
xref: PTHR12027:SF93
organism: Monodelphis domestica

uniprot Q91XZ6 692
type: UnificationXref
id: Q91XZ6
db: uniprot

uniprot F7G3H1 127
type: UnificationXref
id: F7G3H1
db: uniprot

PTHR11937:SF240
type: RelationshipXref
id: PTHR11937:SF240
db: PANTHER Family
relationship type: By Homology

Cadherin 1, type 1, E-cadherin (epithelial)
type: ProteinReference
xref: PTHR24027:SF319
xref: uniprot A0A0R4IFF8 397
organism: Danio rerio

Frizzled
type: ProteinReference
xref: P00475
comment: ENTITY_REFERENCE_ID_DESC=Cadherin signaling pathway.PROTEIN.RECEPTOR.Frizzled
comment: ENTITY_REFERENCE_NOTES=Long Name: Frizzled Synonym: Synonym not specified Accession: P00475
comment: ENTITY_REFERENCE_PROTEIN_TYPE=RECEPTOR
member entity reference: Frizzled-2
member entity reference: Frizzled-8
member entity reference: Frizzled-6
member entity reference: Frizzled-7
member entity reference: FZD10 protein
member entity reference: Frizzled-4
member entity reference: Frizzled-9
member entity reference: Frizzled-10
member entity reference: Frizzled class receptor 3
member entity reference: FZD10 isoform 2
member entity reference: Uncharacterized protein
member entity reference: AGAP010442-PA
member entity reference: FZD9 isoform 1
member entity reference: Frizzled class receptor 5
member entity reference: Frizzled class receptor 1
member entity reference: Frizzled class receptor 6
member entity reference: Frizzled class receptor 8
member entity reference: FZD3 isoform 1
member entity reference: Frizzled class receptor 9b
member entity reference: Frizzled class receptor 7a
member entity reference: Frizzled class receptor 4
member entity reference: Frizzled class receptor 2
member entity reference: Transmembrane receptor LIN-17
member entity reference: Frizzled-1
member entity reference: Frizzled 8a protein
member entity reference: Frizzled-3
member entity reference: Frizzled
member entity reference: Frizzled class receptor 9
member entity reference: Protein mom-5
member entity reference: Frizzled class receptor 7
member entity reference: FZD7 isoform 1
member entity reference: Frizzled class receptor 10
member entity reference: Frizzled-5
member entity reference: Frizzled class receptor 8b
member entity reference: AGAP008871-PA (Fragment)
member entity reference: FZD5 isoform 1

Wnt homolog
type: ProteinReference
xref: PTHR12027:SF70
xref: uniprot G5EG05 880
organism: Caenorhabditis elegans

uniprot F1QGH7 71
type: UnificationXref
id: F1QGH7
db: uniprot

PARTICIPANT STOICHIOMETRY r51 1149
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

uniprot Q28923 1077
type: UnificationXref
id: Q28923
db: uniprot

ncbitaxon 3218 196
type: UnificationXref
id: 3218
db: ncbitaxon

uniprot F6ZXH1 518
type: UnificationXref
id: F6ZXH1
db: uniprot

uniprot Q61088 1033
type: UnificationXref
id: Q61088
db: uniprot

uniprot F6SRK5 72
type: UnificationXref
id: F6SRK5
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot E1BIA5 449
xref: PTHR24027:SF290
organism: Bos taurus

uniprot O00755 895
type: UnificationXref
id: O00755
db: uniprot

uniprot Q9VVG0 743
type: UnificationXref
id: Q9VVG0
db: uniprot

uniprot H2Q4F7 883
type: UnificationXref
id: H2Q4F7
db: uniprot

betacatenin s111 a157 rs5
type: ModificationFeature
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=4.653633157668967
comment: MODIFICATION_RESIDUE_NAME=

uniprot P53497 305
type: UnificationXref
id: P53497
db: uniprot

uniprot Q61527 142
type: UnificationXref
id: Q61527
db: uniprot

Catenin beta-1
type: ProteinReference
xref: PTHR45976:SF4
xref: uniprot F1QGH7 71
organism: Danio rerio

uniprot B8JIQ1 1081
type: UnificationXref
id: B8JIQ1
db: uniprot

Frizzled-9
type: ProteinReference
xref: uniprot O00144 1019
xref: PTHR11309:SF79
organism: Homo sapiens

Cadherin-15
type: ProteinReference
xref: uniprot P33146 595
xref: PTHR24027:SF300
organism: Mus musculus

Cadherin-23
type: ProteinReference
xref: PTHR24027:SF425
xref: uniprot Q9H251 714
organism: Homo sapiens

uniprot A0A1D5QN08 786
type: UnificationXref
id: A0A1D5QN08
db: uniprot

uniprot Q9Y5G7 766
type: UnificationXref
id: Q9Y5G7
db: uniprot

uniprot P70701 935
type: UnificationXref
id: P70701
db: uniprot

uniprot Q9ULB5 730
type: UnificationXref
id: Q9ULB5
db: uniprot

uniprot P07948 1072
type: UnificationXref
id: P07948
db: uniprot

TCF LEF s29 sa23 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: TCF/LEF
stoichiometric coefficient: 1.0

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF75
xref: uniprot H2Q194 881
organism: Pan troglodytes

uniprot C3YP58 222
type: UnificationXref
id: C3YP58
db: uniprot

Protocadherin beta-4
type: ProteinReference
xref: PTHR24028:SF55
xref: uniprot A0A2K6HNB9 427
organism: Pan troglodytes

uniprot P33146 595
type: UnificationXref
id: P33146
db: uniprot

uniprot P21552 907
type: UnificationXref
id: P21552
db: uniprot

IDA
type: EvidenceCodeVocabulary

Yes
type: ProteinReference
xref: P00476
standard name: Oncogene YES1
comment: ENTITY_REFERENCE_NOTES=Long Name: Oncogene YES1 Synonym: Yamaguchi sarcoma oncogene Accession: P00476
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Cadherin signaling pathway.PROTEIN.GENERIC.Yes
member entity reference: Tyrosine-protein kinase
member entity reference: Tyrosine-protein kinase Lyn
member entity reference: Tyrosine-protein kinase Yes

uniprot C3XPR5 825
type: UnificationXref
id: C3XPR5
db: uniprot

Tyrosine-protein kinase
type: ProteinReference
xref: uniprot F6X6I5 1067
organism: Ornithorhynchus anatinus

uniprot H2Q2F4 882
type: UnificationXref
id: H2Q2F4
db: uniprot

Cadherin 17
type: ProteinReference
xref: uniprot A0A2I3RTC9 412
xref: PTHR24027:SF419
organism: Pan troglodytes

uniprot O73864 900
type: UnificationXref
id: O73864
db: uniprot

uniprot Q8WN91 679
type: UnificationXref
id: Q8WN91
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F6VCI6 32
xref: PTHR24054:SF16
organism: Monodelphis domestica

Frizzled class receptor 6
type: ProteinReference
xref: uniprot H2R2C6 1016
xref: PTHR11309:SF75
organism: Pan troglodytes

Protein Wnt-5a
type: ProteinReference
xref: uniprot P41221 921
xref: PTHR12027:SF33
organism: Homo sapiens

uniprot F1N261 1066
type: UnificationXref
id: F1N261
db: uniprot

uniprot D3ZF63 832
type: UnificationXref
id: D3ZF63
db: uniprot

uniprot F6ZW11 517
type: UnificationXref
id: F6ZW11
db: uniprot

HETERODIMER_ASSOCIATION
type: RelationshipTypeVocabulary

Y Fer s64 a7 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y
feature location: Y Fer s64 a7 rs1 Y
modification type: phosphorylated residue
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=Y
comment: MODIFICATION_RESIDUE_ANGLE=3.141592653589793

uniprot F6QWB7 246
type: UnificationXref
id: F6QWB7
db: uniprot

uniprot A0A2I3SKP4 84
type: UnificationXref
id: A0A2I3SKP4
db: uniprot

uniprot Q9NQB0 114
type: UnificationXref
id: Q9NQB0
db: uniprot

uniprot H2Q943 270
type: UnificationXref
id: H2Q943
db: uniprot

Complex (Cadherin/P120)
type: Complex
component stoichiometry: P120 s25 sa25 STOICHIOMETRY ID COMPLEX
component stoichiometry: Cadherin s24 sa24 STOICHIOMETRY ID COMPLEX
component: Cadherin
component: P120
feature: COMPLEX BINDING FEATURE s98 a154 1118
feature: COMPLEX BINDING FEATURE s98 a154 1116
cellular location: cytoplasm

PARTICIPANT STOICHIOMETRY r51 1150
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

uniprot P53478 299
type: UnificationXref
id: P53478
db: uniprot

betacatenin s16 sa10 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

uniprot F6U055 105
type: UnificationXref
id: F6U055
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR10373:SF25
xref: uniprot F1MJS2 103
organism: Bos taurus

uniprot E2QXY7 229
type: UnificationXref
id: E2QXY7
db: uniprot

Emericella nidulans
type: BioSource
xref: ncbitaxon 227321 295

uniprot P34888 918
type: UnificationXref
id: P34888
db: uniprot

uniprot Q5RJH3 646
type: UnificationXref
id: Q5RJH3
db: uniprot

Actin, muscle
type: ProteinReference
xref: PTHR11937:SF359
xref: uniprot W4XTP5 391
organism: Strongylocentrotus purpuratus

uniprot A0A1D5PMG0 399
type: UnificationXref
id: A0A1D5PMG0
db: uniprot

Tyrosine-protein kinase
type: ProteinReference
xref: uniprot E2RBB8 1064
organism: Canis lupus familiaris

uniprot Q80TF3 664
type: UnificationXref
id: Q80TF3
db: uniprot

uniprot Q640S9 1078
type: UnificationXref
id: Q640S9
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F7D992 529
xref: PTHR24027:SF267
organism: Macaca mulatta

uniprot F8VPK8 553
type: UnificationXref
id: F8VPK8
db: uniprot

Casein kinase 2 beta
type: ProteinReference
xref: uniprot A0A2I3TLD4 8
xref: PTHR11740:SF0
organism: Pan troglodytes

uniprot A0A2J8LQ70 814
type: UnificationXref
id: A0A2J8LQ70
db: uniprot

uniprot A2FA04 170
type: UnificationXref
id: A2FA04
db: uniprot

uniprot P62737 317
type: UnificationXref
id: P62737
db: uniprot

Actin, cytoplasmic 1
type: ProteinReference
xref: PTHR11937:SF362
xref: uniprot Q7ZVI7 379
organism: Danio rerio

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A1D5QZ34 406
xref: PTHR24027:SF273
organism: Macaca mulatta

Protocadherin Fat 1
type: ProteinReference
xref: PTHR24026:SF42
xref: uniprot Q14517 622
organism: Homo sapiens

Protein Wnt-4
type: ProteinReference
xref: uniprot P56705 933
xref: PTHR12027:SF101
organism: Homo sapiens

Predicted protein
type: ProteinReference
xref: uniprot A9TYG6 199
xref: PTHR11937:SF387
organism: Physcomitrella patens

PARTICIPANT STOICHIOMETRY r25 1184
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

Protein Wnt-7b
type: ProteinReference
xref: uniprot P56706 934
xref: PTHR12027:SF73
organism: Homo sapiens

PARTICIPANT STOICHIOMETRY r25 1183
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

uniprot F6QHF6 798
type: UnificationXref
id: F6QHF6
db: uniprot

Proto-oncogene Wnt-3
type: ProteinReference
xref: uniprot P56703 931
xref: PTHR12027:SF82
organism: Homo sapiens

Protein Wnt-3a
type: ProteinReference
xref: PTHR12027:SF88
xref: uniprot P56704 932
organism: Homo sapiens

Predicted protein
type: ProteinReference
xref: PTHR11937:SF387
xref: uniprot A9TYG3 198
organism: Physcomitrella patens

PTHR24028:SF253
type: RelationshipXref
id: PTHR24028:SF253
db: PANTHER Family
relationship type: By Homology

PTHR24028:SF255
type: RelationshipXref
id: PTHR24028:SF255
db: PANTHER Family
relationship type: By Homology

PTHR24028:SF254
type: RelationshipXref
id: PTHR24028:SF254
db: PANTHER Family
relationship type: By Homology

uniprot Q6PB90 648
type: UnificationXref
id: Q6PB90
db: uniprot

uniprot F1MXP9 482
type: UnificationXref
id: F1MXP9
db: uniprot

PTHR24028:SF258
type: RelationshipXref
id: PTHR24028:SF258
db: PANTHER Family
relationship type: By Homology

T112 betacatenin s16 sa10 rs3
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY T112
feature location: T112 betacatenin s16 sa10 rs3 T112
modification type: phosphorylated residue
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=T112
comment: MODIFICATION_RESIDUE_ANGLE=-0.0

S betacatenin s119 a170 rs4
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY S
feature location: S betacatenin s119 a170 rs4 S
comment: MODIFICATION_RESIDUE_NAME=S
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=1.6575346654708816

uniprot A9TBG2 195
type: UnificationXref
id: A9TBG2
db: uniprot

uniprot F7GFF0 541
type: UnificationXref
id: F7GFF0
db: uniprot

Protein Wnt-2
type: ProteinReference
xref: PTHR12027:SF86
xref: uniprot P09544 904
organism: Homo sapiens

Protein Wnt-7a
type: ProteinReference
xref: PTHR12027:SF78
xref: uniprot P24383 913
organism: Mus musculus

uniprot F6VM33 1002
type: UnificationXref
id: F6VM33
db: uniprot

PTHR24026:SF100
type: RelationshipXref
id: PTHR24026:SF100
db: PANTHER Family
relationship type: By Homology

PTHR24026:SF101
type: RelationshipXref
id: PTHR24026:SF101
db: PANTHER Family
relationship type: By Homology

Actin A
type: ProteinReference
xref: PTHR11937:SF387
xref: uniprot Q38E94 345
organism: Trypanosoma brucei

uniprot F2Z4N7 244
type: UnificationXref
id: F2Z4N7
db: uniprot

ncbitaxon 3055 188
type: UnificationXref
id: 3055
db: ncbitaxon

Protein Wnt
type: ProteinReference
xref: uniprot F6TCQ4 859
xref: PTHR12027:SF82
organism: Xenopus tropicalis

P120 s25 sa25 rs1
type: ModificationFeature
modification type: phosphorylated residue
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=
comment: MODIFICATION_RESIDUE_ANGLE=3.14

Uncharacterized protein
type: ProteinReference
xref: PTHR24054:SF0
xref: uniprot C3ZBE3 18
organism: Branchiostoma floridae

Receptor tyrosine-protein kinase erbB-2
type: ProteinReference
xref: PTHR24416:SF137
xref: uniprot P70424 138
organism: Mus musculus

Catenin beta 1
type: ProteinReference
xref: uniprot F6WBD5 73
xref: PTHR45976:SF4
organism: Ornithorhynchus anatinus

uniprot Q19319 624
type: UnificationXref
id: Q19319
db: uniprot

PTHR24026:SF108
type: RelationshipXref
id: PTHR24026:SF108
db: PANTHER Family
relationship type: By Homology

uniprot F7BE94 522
type: UnificationXref
id: F7BE94
db: uniprot

PTHR24028:SF244
type: RelationshipXref
id: PTHR24028:SF244
db: PANTHER Family
relationship type: By Homology

PTHR24026:SF106
type: RelationshipXref
id: PTHR24026:SF106
db: PANTHER Family
relationship type: By Homology

uniprot F6XGB0 863
type: UnificationXref
id: F6XGB0
db: uniprot

Transcription factor 7-like 2
type: ProteinReference
xref: PTHR10373:SF32
xref: uniprot Q9NQB0 114
organism: Homo sapiens

PTHR24026:SF105
type: RelationshipXref
id: PTHR24026:SF105
db: PANTHER Family
relationship type: By Homology

Cadherin-20
type: ProteinReference
xref: uniprot Q9Z0M3 784
xref: PTHR24027:SF84
organism: Mus musculus

uniprot P42685 95
type: UnificationXref
id: P42685
db: uniprot

PTHR24028:SF248
type: RelationshipXref
id: PTHR24028:SF248
db: PANTHER Family
relationship type: By Homology

PTHR24026:SF102
type: RelationshipXref
id: PTHR24026:SF102
db: PANTHER Family
relationship type: By Homology

ncbitaxon 284812 292
type: UnificationXref
id: 284812
db: ncbitaxon

PTHR24028:SF247
type: RelationshipXref
id: PTHR24028:SF247
db: PANTHER Family
relationship type: By Homology

Frizzled-9
type: ProteinReference
xref: uniprot Q8K4C8 1043
xref: PTHR11309:SF79
organism: Rattus norvegicus

AGAP003579-PA
type: ProteinReference
xref: PTHR24028:SF146
xref: uniprot Q7QAQ8 662
organism: Anopheles gambiae

Cadherin-20
type: ProteinReference
xref: uniprot Q8QGH3 672
xref: PTHR24027:SF84
organism: Gallus gallus

ACTC1 isoform 1
type: ProteinReference
xref: PTHR11937:SF176
xref: uniprot H2Q943 270
organism: Pan troglodytes

uniprot F6UDC8 499
type: UnificationXref
id: F6UDC8
db: uniprot

Saccharomyces cerevisiae
type: BioSource
xref: ncbitaxon 559292 308

uniprot A0A3Q1LJ38 428
type: UnificationXref
id: A0A3Q1LJ38
db: uniprot

Drosophila melanogaster
type: BioSource
xref: ncbitaxon 7227 42

uniprot F6UBJ7 498
type: UnificationXref
id: F6UBJ7
db: uniprot

uniprot Q2LMP1 941
type: UnificationXref
id: Q2LMP1
db: uniprot

Tyrosine-protein kinase Fer
type: ProteinReference
xref: uniprot P70451 161
xref: PTHR24418:SF227
organism: Mus musculus

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF82
xref: uniprot H2QD96 885
organism: Pan troglodytes

Catenin delta 2
type: ProteinReference
xref: uniprot A0A3Q1NJC6 794
organism: Bos taurus

PTHR24028:SF239
type: RelationshipXref
id: PTHR24028:SF239
db: PANTHER Family
relationship type: By Homology

uniprot K7DJM0 130
type: UnificationXref
id: K7DJM0
db: uniprot

Actin
type: ProteinReference
xref: uniprot Q9UVF3 389
xref: PTHR11937:SF387
organism: Yarrowia lipolytica

PTHR24028:SF234
type: RelationshipXref
id: PTHR24028:SF234
db: PANTHER Family
relationship type: By Homology

uniprot E9HGF5 235
type: UnificationXref
id: E9HGF5
db: uniprot

uniprot E1BIA5 449
type: UnificationXref
id: E1BIA5
db: uniprot

Protein Wnt
type: ProteinReference
xref: uniprot G3V7U3 878
xref: PTHR12027:SF93
organism: Rattus norvegicus

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF414
xref: uniprot F7EU36 263
organism: Monodelphis domestica

Cadherin 9
type: ProteinReference
xref: PTHR24027:SF99
xref: uniprot D3ZFQ5 438
organism: Rattus norvegicus

uniprot F6Y4F1 514
type: UnificationXref
id: F6Y4F1
db: uniprot

uniprot Q75HX0 374
type: UnificationXref
id: Q75HX0
db: uniprot

Cadherin 20
type: ProteinReference
xref: uniprot F7C1R7 526
xref: PTHR24027:SF84
organism: Monodelphis domestica

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF86
xref: uniprot F6XGB0 863
organism: Ornithorhynchus anatinus

uniprot F7F210 264
type: UnificationXref
id: F7F210
db: uniprot

uniprot D3ZTI3 440
type: UnificationXref
id: D3ZTI3
db: uniprot

uniprot Q9UJ99 728
type: UnificationXref
id: Q9UJ99
db: uniprot

uniprot F6SLU9 857
type: UnificationXref
id: F6SLU9
db: uniprot

uniprot F7DIB7 261
type: UnificationXref
id: F7DIB7
db: uniprot

uniprot F7F965 800
type: UnificationXref
id: F7F965
db: uniprot

Plasmodium falciparum
type: BioSource
xref: ncbitaxon 36329 382

PTHR24027:SF290
type: RelationshipXref
id: PTHR24027:SF290
db: PANTHER Family
relationship type: By Homology

uniprot F7ET26 536
type: UnificationXref
id: F7ET26
db: uniprot

Frizzled-4
type: ProteinReference
xref: PTHR11309:SF23
xref: uniprot Q9IA05 1048
organism: Gallus gallus

uniprot F1LXN4 470
type: UnificationXref
id: F1LXN4
db: uniprot

Wnt
type: Protein
entity reference: Wnt
feature: COMPLEX PARTICIPANT BINDING FEATURE s26 sa20 1135
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

Uncharacterized protein
type: ProteinReference
xref: uniprot W4ZD41 393
xref: PTHR11937:SF446
organism: Strongylocentrotus purpuratus

uniprot A0A2I3TBC2 793
type: UnificationXref
id: A0A2I3TBC2
db: uniprot

Glycogen synthase kinase 3 beta
type: ProteinReference
xref: PTHR24057:SF8
xref: uniprot F7ACT4 1084
organism: Xenopus tropicalis

Uncharacterized protein
type: ProteinReference
xref: PTHR24057:SF8
xref: uniprot A0A3Q2TVV5 1080
organism: Gallus gallus

Cytoplasmatic actin
type: ProteinReference
xref: PTHR11937:SF423
xref: uniprot E9HGF5 235
organism: Daphnia pulex

PTHR24028:SF227
type: RelationshipXref
id: PTHR24028:SF227
db: PANTHER Family
relationship type: By Homology

PTHR24028:SF225
type: RelationshipXref
id: PTHR24028:SF225
db: PANTHER Family
relationship type: By Homology

S T Cadherin s1 a10 rs2
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY S T
feature location: S T Cadherin s1 a10 rs2 S T
comment: MODIFICATION_RESIDUE_NAME=S/T
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=0.09

Actin alpha 1, skeletal muscle a
type: ProteinReference
xref: uniprot F1QUN8 241
xref: PTHR11937:SF416
organism: Danio rerio

uniprot P18537 1025
type: UnificationXref
id: P18537
db: uniprot

uniprot F1M702 472
type: UnificationXref
id: F1M702
db: uniprot

uniprot F1M787 797
type: UnificationXref
id: F1M787
db: uniprot

uniprot F7GL73 266
type: UnificationXref
id: F7GL73
db: uniprot

uniprot P34616 598
type: UnificationXref
id: P34616
db: uniprot

Protein Wnt-8a
type: ProteinReference
xref: uniprot Q9H1J5 959
xref: PTHR12027:SF92
organism: Homo sapiens

uniprot P20359 294
type: UnificationXref
id: P20359
db: uniprot

uniprot E2RIL8 988
type: UnificationXref
id: E2RIL8
db: uniprot

Protein Wnt-5b
type: ProteinReference
xref: uniprot Q9H1J7 960
xref: PTHR12027:SF87
organism: Homo sapiens

Protocadherin 10
type: ProteinReference
xref: uniprot F1M6B6 471
xref: PTHR24028:SF0
organism: Rattus norvegicus

Actin, cytoplasmic 1
type: ProteinReference
xref: PTHR11937:SF192
xref: uniprot Q5R1X3 359
organism: Pan troglodytes

Tyrosine-protein kinase
type: ProteinReference
xref: PTHR24418:SF227
xref: uniprot K7CY17 158
organism: Pan troglodytes

uniprot A0A2I3TU99 420
type: UnificationXref
id: A0A2I3TU99
db: uniprot

FZD9 isoform 1
type: ProteinReference
xref: uniprot H2R591 1017
xref: PTHR11309:SF79
organism: Pan troglodytes

uniprot F7ABP2 520
type: UnificationXref
id: F7ABP2
db: uniprot

uniprot F7F2K2 1008
type: UnificationXref
id: F7F2K2
db: uniprot

Frizzled-4
type: ProteinReference
xref: uniprot A0A1D5Q1B1 974
xref: PTHR11309:SF23
organism: Macaca mulatta

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF445
xref: uniprot F6UA54 252
organism: Macaca mulatta

Xenopus tropicalis
type: BioSource
xref: ncbitaxon 8364 30

PTHR11937:SF37
type: RelationshipXref
id: PTHR11937:SF37
db: PANTHER Family
relationship type: By Homology

uniprot Q8I4X0 381
type: UnificationXref
id: Q8I4X0
db: uniprot

Frizzled class receptor 2
type: ProteinReference
xref: uniprot H2QD74 1013
xref: PTHR11309:SF34
organism: Pan troglodytes

uniprot P68032 327
type: UnificationXref
id: P68032
db: uniprot

Cadherin EGF LAG seven-pass G-type receptor 2
type: ProteinReference
xref: PTHR24026:SF32
xref: uniprot Q9R0M0 725
organism: Mus musculus

TRIGGER
type: RelationshipTypeVocabulary

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF84
xref: uniprot D3ZFS0 833
organism: Rattus norvegicus

uniprot Q6NVA9 366
type: UnificationXref
id: Q6NVA9
db: uniprot

Cadherin 18
type: ProteinReference
xref: uniprot F6Y5X3 515
xref: PTHR24027:SF106
organism: Canis lupus familiaris

uniprot F6WDU9 509
type: UnificationXref
id: F6WDU9
db: uniprot

uniprot E9GTE8 24
type: UnificationXref
id: E9GTE8
db: uniprot

Actin-related protein 2
type: ProteinReference
xref: PTHR11937:SF37
xref: uniprot Q5M7U6 357
organism: Rattus norvegicus

Cadherin-2
type: ProteinReference
xref: uniprot P19022 592
xref: PTHR24027:SF79
organism: Homo sapiens

Receptor tyrosine-protein kinase erbB-3
type: ProteinReference
xref: uniprot P21860 136
xref: PTHR24416:SF88
organism: Homo sapiens

uniprot P10987 290
type: UnificationXref
id: P10987
db: uniprot

uniprot C3XYW6 826
type: UnificationXref
id: C3XYW6
db: uniprot

PARTICIPANT STOICHIOMETRY r24 1186
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

Protein Wnt-9a
type: ProteinReference
xref: PTHR12027:SF75
xref: uniprot Q8R5M2 952
organism: Mus musculus

PARTICIPANT STOICHIOMETRY r24 1185
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

ncbitaxon 9913 26
type: UnificationXref
id: 9913
db: ncbitaxon

Protein Wnt-8b
type: ProteinReference
xref: PTHR12027:SF94
xref: uniprot Q9WUD6 968
organism: Mus musculus

Protein Wnt-4
type: ProteinReference
xref: PTHR12027:SF111
xref: uniprot P40589 920
organism: Drosophila melanogaster

uniprot Q9Y5H0 768
type: UnificationXref
id: Q9Y5H0
db: uniprot

Proto-oncogene tyrosine-protein kinase Src
type: ProteinReference
xref: PTHR24418:SF53
xref: uniprot Q9WUD9 154
organism: Rattus norvegicus

uniprot D3ZND6 834
type: UnificationXref
id: D3ZND6
db: uniprot

uniprot P53488 300
type: UnificationXref
id: P53488
db: uniprot

uniprot A0A0A6YY83 394
type: UnificationXref
id: A0A0A6YY83
db: uniprot

uniprot O54833 39
type: UnificationXref
id: O54833
db: uniprot

uniprot F6RFW8 248
type: UnificationXref
id: F6RFW8
db: uniprot

uniprot F6X3B2 862
type: UnificationXref
id: F6X3B2
db: uniprot

uniprot F1MEW8 847
type: UnificationXref
id: F1MEW8
db: uniprot

Cadherin-17
type: ProteinReference
xref: uniprot Q9R100 727
xref: PTHR24027:SF419
organism: Mus musculus

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF94
xref: uniprot F7D4J8 868
organism: Monodelphis domestica

uniprot X1WEJ5 971
type: UnificationXref
id: X1WEJ5
db: uniprot

Y142 betacatenin s28 sa22 rs2
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y142
feature location: Y142 betacatenin s28 sa22 rs2 Y142
comment: MODIFICATION_RESIDUE_NAME=Y142
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=2.893781136851091

Actin, cytoplasmic 2
type: ProteinReference
xref: uniprot Q7ZVF9 378
xref: PTHR11937:SF362
organism: Danio rerio

T112 betacatenin s28 sa22 rs3
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY T112
feature location: T112 betacatenin s28 sa22 rs3 T112
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=T112
comment: MODIFICATION_RESIDUE_ANGLE=-0.0

Uncharacterized protein
type: ProteinReference
xref: PTHR24027:SF322
xref: uniprot F6YS32 516
organism: Macaca mulatta

uniprot F7DGM2 530
type: UnificationXref
id: F7DGM2
db: uniprot

uniprot Q91Y03 698
type: UnificationXref
id: Q91Y03
db: uniprot

uniprot Q9VFH5 742
type: UnificationXref
id: Q9VFH5
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF201
xref: uniprot F6UA63 253
organism: Macaca mulatta

uniprot F1P258 125
type: UnificationXref
id: F1P258
db: uniprot

Casein kinase II subunit alpha
type: ProteinReference
xref: uniprot P21868 50
xref: PTHR24054:SF16
organism: Gallus gallus

Protein Wnt-4a
type: ProteinReference
xref: PTHR12027:SF105
xref: uniprot P47793 923
organism: Danio rerio

Casein kinase II subunit beta
type: ProteinReference
xref: PTHR11740:SF0
xref: uniprot A7SG27 10
organism: Nematostella vectensis

uniprot O96014 901
type: UnificationXref
id: O96014
db: uniprot

uniprot Q61086 1032
type: UnificationXref
id: Q61086
db: uniprot

uniprot H2QD74 1013
type: UnificationXref
id: H2QD74
db: uniprot

Tyrosine-protein kinase
type: ProteinReference
xref: PTHR24418:SF90
xref: uniprot F7G374 1069
organism: Monodelphis domestica

uniprot Q9HCS4 113
type: UnificationXref
id: Q9HCS4
db: uniprot

uniprot F6SH04 999
type: UnificationXref
id: F6SH04
db: uniprot

Actin, alpha 2, smooth muscle, aorta
type: ProteinReference
xref: PTHR11937:SF201
xref: uniprot F2Z4N0 243
organism: Canis lupus familiaris

Protocadherin 9
type: ProteinReference
xref: uniprot F1MMW5 480
xref: PTHR24028:SF248
organism: Bos taurus

uniprot A0A1W2WEN5 166
type: UnificationXref
id: A0A1W2WEN5
db: uniprot

Y654 betacatenin s111 a157 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y654
feature location: Y654 betacatenin s111 a157 rs1 Y654
comment: MODIFICATION_RESIDUE_ANGLE=3.3479165476195107
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=Y654

Protocadherin beta 1
type: ProteinReference
xref: PTHR24028:SF12
xref: uniprot Q91Y08 702
organism: Mus musculus

Cadherin-related family member 1
type: ProteinReference
xref: PTHR24028:SF263
xref: uniprot Q8WN91 679
organism: Bos taurus

Cadherin 18
type: ProteinReference
xref: PTHR24027:SF106
xref: uniprot F1M702 472
organism: Rattus norvegicus

uniprot O55134 579
type: UnificationXref
id: O55134
db: uniprot

MCG141300
type: ProteinReference
xref: PTHR24028:SF95
xref: uniprot Q91Y07 701
organism: Mus musculus

Actin, gamma 2, smooth muscle, enteric
type: ProteinReference
xref: PTHR11937:SF445
xref: uniprot F2Z4N8 245
organism: Canis lupus familiaris

Actin, alpha, cardiac muscle 1
type: ProteinReference
xref: PTHR11937:SF176
xref: uniprot F2Z4N7 244
organism: Canis lupus familiaris

MCG141291
type: ProteinReference
xref: PTHR24028:SF61
xref: uniprot Q91Y03 698
organism: Mus musculus

Protocadherin beta 15
type: ProteinReference
xref: PTHR24028:SF69
xref: uniprot Q91Y04 699
organism: Mus musculus

PTHR24057:SF8
type: RelationshipXref
id: PTHR24057:SF8
db: PANTHER Family
relationship type: By Homology

Protocadherin beta 13
type: ProteinReference
xref: uniprot Q91Y06 700
xref: PTHR24028:SF104
organism: Mus musculus

Tyrosine phosphatases
type: Protein
entity reference: Tyrosine phosphatases
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

uniprot P68033 328
type: UnificationXref
id: P68033
db: uniprot

CDH20 isoform 1
type: ProteinReference
xref: uniprot A0A2J8NDG6 425
xref: PTHR24027:SF84
organism: Pan troglodytes

Protocadherin beta 2
type: ProteinReference
xref: PTHR24028:SF281
xref: uniprot Q91Y00 695
organism: Mus musculus

MCG141286
type: ProteinReference
xref: PTHR24028:SF91
xref: uniprot Q91Y01 696
organism: Mus musculus

Protocadherin beta-18
type: ProteinReference
xref: PTHR24028:SF54
xref: uniprot Q91Y02 697
organism: Mus musculus

PTHR24026:SF76
type: RelationshipXref
id: PTHR24026:SF76
db: PANTHER Family
relationship type: By Homology

CaDHerin family
type: ProteinReference
xref: PTHR24026:SF97
xref: uniprot Q19194 623
organism: Caenorhabditis elegans

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF72
xref: uniprot J9NZJ2 890
organism: Canis lupus familiaris

PTHR24026:SF75
type: RelationshipXref
id: PTHR24026:SF75
db: PANTHER Family
relationship type: By Homology

uniprot A2VDQ6 434
type: UnificationXref
id: A2VDQ6
db: uniprot

PTHR24416:SF566
type: RelationshipXref
id: PTHR24416:SF566
db: PANTHER Family
relationship type: By Homology

uniprot A0A2I3RF60 121
type: UnificationXref
id: A0A2I3RF60
db: uniprot

Protein Wnt
type: ProteinReference
xref: uniprot G3V819 879
xref: PTHR12027:SF7
organism: Rattus norvegicus

Bos taurus
type: BioSource
xref: ncbitaxon 9913 26

Actin alpha cardiac muscle 1b
type: ProteinReference
xref: PTHR11937:SF184
xref: uniprot Q9I8V1 386
organism: Danio rerio

uniprot Q9Y5E2 746
type: UnificationXref
id: Q9Y5E2
db: uniprot

uniprot Q8VHR0 678
type: UnificationXref
id: Q8VHR0
db: uniprot

uniprot Q9R216 1054
type: UnificationXref
id: Q9R216
db: uniprot

uniprot Q24298 626
type: UnificationXref
id: Q24298
db: uniprot

Complex (Cadherin/betacatenin/ alphacatenin/F-actin)
type: Complex
component stoichiometry: betacatenin s20 sa14 STOICHIOMETRY ID COMPLEX
component stoichiometry: Cadherin s19 sa13 STOICHIOMETRY ID COMPLEX
component stoichiometry: F actin s23 sa16 STOICHIOMETRY ID COMPLEX
component stoichiometry: alphacatenin s21 sa15 STOICHIOMETRY ID COMPLEX
component: alphacatenin
component: F-actin
component: betacatenin
component: Cadherin
feature: COMPLEX BINDING FEATURE s77 a110 1112
feature: COMPLEX BINDING FEATURE s77 a110 1114
feature: COMPLEX BINDING FEATURE s77 a110 1110
feature: COMPLEX BINDING FEATURE s77 a110 1108
cellular location: cytoplasm

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF359
xref: uniprot H3F5B4 272
organism: Pristionchus pacificus

Frizzled class receptor 8
type: ProteinReference
xref: uniprot F7CDC6 1004
xref: PTHR11309:SF90
organism: Monodelphis domestica

IEA
type: EvidenceCodeVocabulary
xref: eco ECO:0000501 658

uniprot Q6GL68 111
type: UnificationXref
id: Q6GL68
db: uniprot

uniprot A0A2I3TI13 812
type: UnificationXref
id: A0A2I3TI13
db: uniprot

PHYSICAL_STIMULATION
type: Control
xref: PHYSICAL STIMULATION
controlled: Wnt Targetz transcription
controller: Complex (betacatenin/TCF/LEF)

uniprot B1WBR9 824
type: UnificationXref
id: B1WBR9
db: uniprot

Actin
type: ProteinReference
xref: uniprot Q7YTV5 377
xref: PTHR11937:SF387
organism: Trichoplax adhaerens

Cadherin-12
type: ProteinReference
xref: PTHR24027:SF96
xref: uniprot Q5RJH3 646
organism: Mus musculus

uniprot B7PBG2 209
type: UnificationXref
id: B7PBG2
db: uniprot

RCG37051
type: ProteinReference
xref: uniprot F1LS01 469
xref: PTHR24028:SF248
organism: Rattus norvegicus

uniprot Q9Z1J1 119
type: UnificationXref
id: Q9Z1J1
db: uniprot

Cadherin 24
type: ProteinReference
xref: uniprot D3ZTI3 440
xref: PTHR24027:SF272
organism: Rattus norvegicus

FZD10 protein
type: ProteinReference
xref: uniprot A3KMX5 978
xref: PTHR11309:SF86
organism: Bos taurus

uniprot P00523 151
type: UnificationXref
id: P00523
db: uniprot

Epidermal growth factor receptor
type: ProteinReference
xref: uniprot Q01279 139
xref: PTHR24416:SF91
organism: Mus musculus

uniprot G3V8P1 556
type: UnificationXref
id: G3V8P1
db: uniprot

Ixodes scapularis
type: BioSource
xref: ncbitaxon 6945 17

uniprot P07947 1071
type: UnificationXref
id: P07947
db: uniprot

F actin s11 sa3 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: F-actin
stoichiometric coefficient: 1.0

Cadherin-related family member 1
type: ProteinReference
xref: PTHR24028:SF263
xref: uniprot F1NKC9 483
organism: Gallus gallus

uniprot Q5E9B5 354
type: UnificationXref
id: Q5E9B5
db: uniprot

uniprot H2QQP7 568
type: UnificationXref
id: H2QQP7
db: uniprot

PTHR24026:SF97
type: RelationshipXref
id: PTHR24026:SF97
db: PANTHER Family
relationship type: By Homology

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF89
xref: uniprot F1MEW8 847
organism: Bos taurus

Protein Wnt
type: ProteinReference
xref: uniprot F1MN70 849
xref: PTHR12027:SF72
organism: Bos taurus

Uncharacterized protein
type: ProteinReference
xref: uniprot F6SRK5 72
xref: PTHR45976:SF4
organism: Monodelphis domestica

Y142 betacatenin s16 sa10 rs2
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y142
feature location: Y142 betacatenin s16 sa10 rs2 Y142
comment: MODIFICATION_RESIDUE_NAME=Y142
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=2.893781136851091

PTHR24026:SF93
type: RelationshipXref
id: PTHR24026:SF93
db: PANTHER Family
relationship type: By Homology

Protocadherin 7
type: ProteinReference
xref: PTHR24028:SF253
xref: uniprot E1BCK4 447
organism: Bos taurus

Cadherin EGF LAG seven-pass G-type receptor 2
type: ProteinReference
xref: uniprot Q9HCU4 718
xref: PTHR24026:SF32
organism: Homo sapiens

uniprot G3V8N1 554
type: UnificationXref
id: G3V8N1
db: uniprot

Casein kinase 2 alpha subunit
type: ProteinReference
xref: PTHR24054:SF0
xref: uniprot Q8T3S5 65
organism: Ciona intestinalis

uniprot P10981 287
type: UnificationXref
id: P10981
db: uniprot

Receptor protein-tyrosine kinase
type: ProteinReference
xref: uniprot F1MCQ7 124
xref: PTHR24416:SF137
organism: Bos taurus

uniprot P55291 610
type: UnificationXref
id: P55291
db: uniprot

Putative actin-22
type: ProteinReference
xref: uniprot Q553U6 349
xref: PTHR11937:SF421
organism: Dictyostelium discoideum

uniprot A0A0K3AWM6 972
type: UnificationXref
id: A0A0K3AWM6
db: uniprot

alphacatenin s10 sa2 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: alphacatenin
stoichiometric coefficient: 1.0

Actin, gamma
type: ProteinReference
xref: uniprot P20359 294
xref: PTHR11937:SF387
organism: Emericella nidulans

uniprot Q91XZ5 691
type: UnificationXref
id: Q91XZ5
db: uniprot

Gallus gallus
type: BioSource
xref: ncbitaxon 9031 51

Uncharacterized protein
type: ProteinReference
xref: PTHR24027:SF273
xref: uniprot F7EXZ6 537
organism: Monodelphis domestica

PTHR24026:SF89
type: RelationshipXref
id: PTHR24026:SF89
db: PANTHER Family
relationship type: By Homology

uniprot Q9EQD0 1046
type: UnificationXref
id: Q9EQD0
db: uniprot

uniprot Q9WU82 81
type: UnificationXref
id: Q9WU82
db: uniprot

uniprot P67868 53
type: UnificationXref
id: P67868
db: uniprot

PTHR24027:SF267
type: RelationshipXref
id: PTHR24027:SF267
db: PANTHER Family
relationship type: By Homology

uniprot B3RX77 207
type: UnificationXref
id: B3RX77
db: uniprot

Protocadherin 1
type: ProteinReference
xref: PTHR24028:SF247
xref: uniprot F6ZXH1 518
organism: Xenopus tropicalis

Frizzled-10
type: ProteinReference
xref: PTHR11309:SF86
xref: uniprot Q8BKG4 1041
organism: Mus musculus

uniprot A0A1D5Q2V8 402
type: UnificationXref
id: A0A1D5Q2V8
db: uniprot

uniprot F7BIQ7 523
type: UnificationXref
id: F7BIQ7
db: uniprot

F actin s4 sa7 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: F-actin
stoichiometric coefficient: 1.0

Cadherin-11
type: ProteinReference
xref: uniprot A0A1D5P6T7 398
xref: PTHR24027:SF85
organism: Gallus gallus

Actin
type: ProteinReference
xref: uniprot E3K4I1 230
xref: PTHR11937:SF387
organism: Puccinia graminis

uniprot A9TYG6 199
type: UnificationXref
id: A9TYG6
db: uniprot

Cadherin-17
type: ProteinReference
xref: PTHR24027:SF419
xref: uniprot Q12864 620
organism: Homo sapiens

uniprot A0A2J8N8E6 976
type: UnificationXref
id: A0A2J8N8E6
db: uniprot

uniprot P18031 789
type: UnificationXref
id: P18031
db: uniprot

uniprot Q9PWH2 1052
type: UnificationXref
id: Q9PWH2
db: uniprot

uniprot E1BEN9 841
type: UnificationXref
id: E1BEN9
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR11937:SF468
xref: uniprot C3Z4K3 223
organism: Branchiostoma floridae

Protocadherin-8
type: ProteinReference
xref: PTHR24028:SF46
xref: uniprot O95206 586
organism: Homo sapiens

alphacatenin
type: Protein
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

Neural-cadherin
type: ProteinReference
xref: PTHR24025:SF23
xref: uniprot O15943 577
organism: Drosophila melanogaster

Uncharacterized protein
type: ProteinReference
xref: uniprot F7E9X7 799
organism: Monodelphis domestica

uniprot Q5DRC6 631
type: UnificationXref
id: Q5DRC6
db: uniprot

uniprot C3ZMR2 226
type: UnificationXref
id: C3ZMR2
db: uniprot

uniprot P55245 137
type: UnificationXref
id: P55245
db: uniprot

Tyrosine-protein phosphatase non-receptor type
type: ProteinReference
xref: uniprot A0A1D5QN08 786
organism: Macaca mulatta

AGAP001676-PA
type: ProteinReference
xref: PTHR11937:SF397
xref: uniprot Q7PXZ8 375
organism: Anopheles gambiae

uniprot F7EKI5 535
type: UnificationXref
id: F7EKI5
db: uniprot

uniprot Q9QXN1 115
type: UnificationXref
id: Q9QXN1
db: uniprot

uniprot P27467 914
type: UnificationXref
id: P27467
db: uniprot

uniprot D4A9J2 839
type: UnificationXref
id: D4A9J2
db: uniprot

Cadherin-10
type: ProteinReference
xref: PTHR24027:SF290
xref: uniprot Q9Y6N8 783
organism: Homo sapiens

PTHR24027:SF272
type: RelationshipXref
id: PTHR24027:SF272
db: PANTHER Family
relationship type: By Homology

Frizzled-8
type: ProteinReference
xref: uniprot Q9H461 1047
xref: PTHR11309:SF90
organism: Homo sapiens

uniprot C3YZ17 828
type: UnificationXref
id: C3YZ17
db: uniprot

PARTICIPANT STOICHIOMETRY r47 1166
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

Uncharacterized protein
type: ProteinReference
xref: uniprot F7GBV2 540
xref: PTHR24026:SF38
organism: Macaca mulatta

PARTICIPANT STOICHIOMETRY r47 1167
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

Predicted protein
type: ProteinReference
xref: uniprot A9V489 201
xref: PTHR11937:SF387
organism: Monosiga brevicollis

PTHR24027:SF273
type: RelationshipXref
id: PTHR24027:SF273
db: PANTHER Family
relationship type: By Homology

uniprot F7FK62 872
type: UnificationXref
id: F7FK62
db: uniprot

uniprot H2QE24 271
type: UnificationXref
id: H2QE24
db: uniprot

Actin, alpha cardiac muscle 2
type: ProteinReference
xref: uniprot P20399 296
xref: PTHR11937:SF416
organism: Xenopus tropicalis

PCDH9 isoform 4
type: ProteinReference
xref: PTHR24028:SF248
xref: uniprot H2R0P7 574
organism: Pan troglodytes

uniprot E2RTG8 846
type: UnificationXref
id: E2RTG8
db: uniprot

Frizzled class receptor 1
type: ProteinReference
xref: PTHR11309:SF81
xref: uniprot F7E9U1 1006
organism: Monodelphis domestica

Putative actin-23
type: ProteinReference
xref: uniprot Q55EU6 350
xref: PTHR11937:SF154
organism: Dictyostelium discoideum

uniprot H2QTL3 92
type: UnificationXref
id: H2QTL3
db: uniprot

uniprot P21868 50
type: UnificationXref
id: P21868
db: uniprot

Actin, cytoplasmic 1
type: ProteinReference
xref: PTHR11937:SF192
xref: uniprot P60710 311
organism: Mus musculus

Actin, cytoplasmic 1
type: ProteinReference
xref: PTHR11937:SF192
xref: uniprot P60711 312
organism: Rattus norvegicus

Actin, cytoplasmic 1
type: ProteinReference
xref: PTHR11937:SF192
xref: uniprot P60712 313
organism: Bos taurus

uniprot P56704 932
type: UnificationXref
id: P56704
db: uniprot

Follistatin-related protein 1
type: ProteinReference
xref: uniprot Q12841 937
xref: PTHR10913:SF13
organism: Homo sapiens

betacatenin
type: Protein
entity reference: betacatenin
feature: T112 betacatenin s16 sa10 rs3
feature: COMPLEX PARTICIPANT BINDING FEATURE s16 sa10 1129
feature: Y654 betacatenin s16 sa10 rs1
feature: S betacatenin s16 sa10 rs4
feature: Y142 betacatenin s16 sa10 rs2
feature: betacatenin s16 sa10 rs5
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

ncbitaxon 6945 17
type: UnificationXref
id: 6945
db: ncbitaxon

Y142 betacatenin s13 sa5 rs2
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y142
feature location: Y142 betacatenin s13 sa5 rs2 Y142
comment: MODIFICATION_RESIDUE_NAME=Y142
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=2.893781136851091

GSK3beta
type: Protein
entity reference: GSK3beta
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

Frizzled class receptor 8b
type: ProteinReference
xref: PTHR11309:SF140
xref: uniprot B0S6S2 982
organism: Danio rerio

Actin-like protein 53D
type: ProteinReference
xref: uniprot P45891 297
xref: PTHR11937:SF387
organism: Drosophila melanogaster

uniprot Q7YTV5 377
type: UnificationXref
id: Q7YTV5
db: uniprot

Protocadherin beta 14
type: ProteinReference
xref: uniprot D3ZM08 439
xref: PTHR24028:SF139
organism: Rattus norvegicus

uniprot O35468 898
type: UnificationXref
id: O35468
db: uniprot

uniprot J9P2Q5 891
type: UnificationXref
id: J9P2Q5
db: uniprot

Actin, cytoplasmic 1
type: ProteinReference
xref: PTHR11937:SF192
xref: uniprot P60709 310
organism: Homo sapiens

uniprot A7S0V7 181
type: UnificationXref
id: A7S0V7
db: uniprot

Actin, cytoplasmic 1
type: ProteinReference
xref: PTHR11937:SF192
xref: uniprot P60706 309
organism: Gallus gallus

Y Cadherin s12 sa4 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y
feature location: Y Cadherin s12 sa4 rs1 Y
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=Y
comment: MODIFICATION_RESIDUE_ANGLE=3.14

uniprot A8JAV1 187
type: UnificationXref
id: A8JAV1
db: uniprot

ncbitaxon 5722 171
type: UnificationXref
id: 5722
db: ncbitaxon

uniprot F6SJ04 497
type: UnificationXref
id: F6SJ04
db: uniprot

GO GO:0005737 3
type: UnificationXref
id: GO:0005737
db: GO

S betacatenin s93 a132 rs4
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY S
feature location: S betacatenin s93 a132 rs4 S
modification type: phosphorylated residue
comment: MODIFICATION_RESIDUE_NAME=S
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=1.6575346654708816

Oryza sativa
type: BioSource
xref: ncbitaxon 39947 176

uniprot Q9YI00 1060
type: UnificationXref
id: Q9YI00
db: uniprot

uniprot D3ZE55 437
type: UnificationXref
id: D3ZE55
db: uniprot

Cadherin-10
type: ProteinReference
xref: uniprot P70408 613
xref: PTHR24027:SF290
organism: Mus musculus

Cadherin-9
type: ProteinReference
xref: PTHR24027:SF99
xref: uniprot P70407 612
organism: Mus musculus

uniprot Q5DRD7 638
type: UnificationXref
id: Q5DRD7
db: uniprot

uniprot Q28IC7 939
type: UnificationXref
id: Q28IC7
db: uniprot

Protocadherin beta-8
type: ProteinReference
xref: PTHR24028:SF150
xref: uniprot Q9UN66 731
organism: Homo sapiens

Protocadherin beta-10
type: ProteinReference
xref: PTHR24028:SF54
xref: uniprot Q9UN67 732
organism: Homo sapiens

PARTICIPANT STOICHIOMETRY r44 1174
type: Stoichiometry
physical entity: Complex (Cadherin/P120)
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r44 1172
type: Stoichiometry
physical entity: Cadherin
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r44 1173
type: Stoichiometry
physical entity: P120
stoichiometric coefficient: 1.0

Cadherin-18
type: ProteinReference
xref: PTHR24027:SF106
xref: uniprot Q08DJ5 619
organism: Bos taurus

PCDHGC3 protein
type: ProteinReference
xref: PTHR24028:SF70
xref: uniprot A5D7F4 435
organism: Bos taurus

Protein CBR-EGL-20
type: ProteinReference
xref: PTHR12027:SF70
xref: uniprot A8WV58 821
organism: Caenorhabditis briggsae

uniprot Q7PR41 655
type: UnificationXref
id: Q7PR41
db: uniprot

uniprot P63259 320
type: UnificationXref
id: P63259
db: uniprot

uniprot A0A3Q1M024 431
type: UnificationXref
id: A0A3Q1M024
db: uniprot

Frizzled-3
type: ProteinReference
xref: uniprot F6QL95 996
xref: PTHR11309:SF22
organism: Macaca mulatta

P120
type: Protein
entity reference: P120
feature: P120 s110 a156 rs1
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

uniprot G3X6Y5 559
type: UnificationXref
id: G3X6Y5
db: uniprot

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF93
xref: uniprot A0A1D5QFE1 809
organism: Macaca mulatta

Cadherin 22
type: ProteinReference
xref: PTHR24027:SF311
xref: uniprot A0A3Q1MCN6 432
organism: Bos taurus

MCG133388, isoform CRA_f
type: ProteinReference
xref: uniprot Q91XW9 688
xref: PTHR24028:SF258
organism: Mus musculus

Actin alpha 2, smooth muscle
type: ProteinReference
xref: PTHR11937:SF445
xref: uniprot Q6DHS1 363
organism: Danio rerio

uniprot F7H7P6 874
type: UnificationXref
id: F7H7P6
db: uniprot

uniprot Q5DRD1 634
type: UnificationXref
id: Q5DRD1
db: uniprot

Cadherin-4
type: ProteinReference
xref: uniprot A0A1D5PQ72 400
xref: PTHR24027:SF81
organism: Gallus gallus

Frizzled-10
type: ProteinReference
xref: uniprot Q9PWH2 1052
xref: PTHR11309:SF86
organism: Gallus gallus

uniprot F1PD90 488
type: UnificationXref
id: F1PD90
db: uniprot

Catenin delta-2
type: ProteinReference
xref: uniprot F1M787 797
organism: Rattus norvegicus

uniprot A0A2I3TLD4 8
type: UnificationXref
id: A0A2I3TLD4
db: uniprot

Proto-oncogene tyrosine-protein kinase Src
type: ProteinReference
xref: uniprot P12931 153
xref: PTHR24418:SF53
organism: Homo sapiens

P120
type: Protein
entity reference: P120
feature: COMPLEX PARTICIPANT BINDING FEATURE s25 sa25 1119
feature: P120 s25 sa25 rs1
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

betacatenin
type: Protein
entity reference: betacatenin
feature: Y654 betacatenin s94 a133 rs1
feature: S betacatenin s94 a133 rs4
feature: Y142 betacatenin s94 a133 rs2
feature: T112 betacatenin s94 a133 rs3
feature: betacatenin s94 a133 rs5
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

uniprot F6WZD8 511
type: UnificationXref
id: F6WZD8
db: uniprot

Casein kinase II subunit alpha
type: ProteinReference
xref: PTHR24054:SF0
xref: uniprot P18334 45
organism: Caenorhabditis elegans

uniprot P51030 930
type: UnificationXref
id: P51030
db: uniprot

uniprot E9PXQ7 464
type: UnificationXref
id: E9PXQ7
db: uniprot

uniprot F6PWM3 994
type: UnificationXref
id: F6PWM3
db: uniprot

uniprot A0A2I3SSM9 100
type: UnificationXref
id: A0A2I3SSM9
db: uniprot

PTHR24418:SF90
type: RelationshipXref
id: PTHR24418:SF90
db: PANTHER Family
relationship type: By Homology

Trichoplax adhaerens
type: BioSource
xref: ncbitaxon 10228 206

uniprot Q66II0 949
type: UnificationXref
id: Q66II0
db: uniprot

Protein Wnt-9b
type: ProteinReference
xref: PTHR12027:SF84
xref: uniprot O35468 898
organism: Mus musculus

uniprot F6T6M8 31
type: UnificationXref
id: F6T6M8
db: uniprot

ncbitaxon 185431 346
type: UnificationXref
id: 185431
db: ncbitaxon

uniprot P19022 592
type: UnificationXref
id: P19022
db: uniprot

alphacatenin
type: Protein
feature: COMPLEX PARTICIPANT BINDING FEATURE s10 sa2 1123
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

Cadherin 12
type: ProteinReference
xref: PTHR24027:SF96
xref: uniprot E2R790 456
organism: Canis lupus familiaris

PANTHER Pathway P00012 1
type: UnificationXref
id: P00012
db: PANTHER Pathway

Frizzled class receptor 4
type: ProteinReference
xref: uniprot K7AZD4 1018
xref: PTHR11309:SF23
organism: Pan troglodytes

Uncharacterized protein
type: ProteinReference
xref: uniprot F7EZ48 1007
xref: PTHR11309:SF86
organism: Macaca mulatta

ncbitaxon 10228 206
type: UnificationXref
id: 10228
db: ncbitaxon

uniprot B3S5E4 208
type: UnificationXref
id: B3S5E4
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F6PGQ1 1083
xref: PTHR24057:SF8
organism: Monodelphis domestica

uniprot A0A1D5PQ72 400
type: UnificationXref
id: A0A1D5PQ72
db: uniprot

uniprot P56706 934
type: UnificationXref
id: P56706
db: uniprot

uniprot Q9Y5H7 775
type: UnificationXref
id: Q9Y5H7
db: uniprot

ncbitaxon 7955 60
type: UnificationXref
id: 7955
db: ncbitaxon

uniprot A0A2I3RPI4 411
type: UnificationXref
id: A0A2I3RPI4
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F6SJ04 497
xref: PTHR24028:SF248
organism: Monodelphis domestica

eco ECO:0000250 6
type: UnificationXref
id: ECO:0000250
db: eco

ncbitaxon 214684 356
type: UnificationXref
id: 214684
db: ncbitaxon

uniprot A9V489 201
type: UnificationXref
id: A9V489
db: uniprot

uniprot Q8N6Y1 671
type: UnificationXref
id: Q8N6Y1
db: uniprot

uniprot Q9H159 713
type: UnificationXref
id: Q9H159
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot E2RHZ1 20
xref: PTHR24054:SF16
organism: Canis lupus familiaris

Catenin beta-1
type: ProteinReference
xref: PTHR45976:SF4
xref: uniprot Q9WU82 81
organism: Rattus norvegicus

uniprot D3ZM08 439
type: UnificationXref
id: D3ZM08
db: uniprot

uniprot Q61090 1035
type: UnificationXref
id: Q61090
db: uniprot

Receptor protein-tyrosine kinase
type: ProteinReference
xref: PTHR24416:SF90
xref: uniprot F6ZSZ9 126
organism: Monodelphis domestica

uniprot Q8R5M2 952
type: UnificationXref
id: Q8R5M2
db: uniprot

uniprot Q5TP56 946
type: UnificationXref
id: Q5TP56
db: uniprot

uniprot E9FXV8 233
type: UnificationXref
id: E9FXV8
db: uniprot

Schizosaccharomyces pombe
type: BioSource
xref: ncbitaxon 284812 292

Actin
type: ProteinReference
xref: PTHR11937:SF387
xref: uniprot Q75D00 372
organism: Ashbya gossypii

Ashbya gossypii
type: BioSource
xref: ncbitaxon 284811 373

Protocadherin beta 8
type: ProteinReference
xref: PTHR24028:SF90
xref: uniprot G3V8N7 555
organism: Rattus norvegicus

uniprot F7G2C9 91
type: UnificationXref
id: F7G2C9
db: uniprot

Tyrosine phosphatases
type: Protein
entity reference: Tyrosine phosphatases
feature: COMPLEX PARTICIPANT BINDING FEATURE s33 sa18 1097
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

uniprot Q8R508 674
type: UnificationXref
id: Q8R508
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__betacatenin-RIGHT__betacatenin-_r39
controller: Complex (Wnt/Frizzled)

Cadherin-7
type: ProteinReference
xref: uniprot Q5DWV2 644
xref: PTHR24027:SF91
organism: Rattus norvegicus

uniprot F6UA63 253
type: UnificationXref
id: F6UA63
db: uniprot

uniprot A8XFP5 12
type: UnificationXref
id: A8XFP5
db: uniprot

uniprot A0A3Q1M1A0 815
type: UnificationXref
id: A0A3Q1M1A0
db: uniprot

Cadherin-20
type: ProteinReference
xref: uniprot Q5DWV1 643
xref: PTHR24027:SF84
organism: Rattus norvegicus

uniprot P17553 906
type: UnificationXref
id: P17553
db: uniprot

PTHR24027:SF311
type: RelationshipXref
id: PTHR24027:SF311
db: PANTHER Family
relationship type: By Homology

uniprot F7GJC2 542
type: UnificationXref
id: F7GJC2
db: uniprot

uniprot Q5M7U6 357
type: UnificationXref
id: Q5M7U6
db: uniprot

uniprot F6S0B5 495
type: UnificationXref
id: F6S0B5
db: uniprot

Protein CBR-CWN-2
type: ProteinReference
xref: uniprot A8WV10 820
xref: PTHR12027:SF77
organism: Caenorhabditis briggsae

Cadherin 18
type: ProteinReference
xref: PTHR24027:SF106
xref: uniprot F6VFP8 507
organism: Ornithorhynchus anatinus

Protocadherin beta 22
type: ProteinReference
xref: PTHR24028:SF97
xref: uniprot G3V8N1 554
organism: Rattus norvegicus

FAT atypical cadherin 1
type: ProteinReference
xref: PTHR24026:SF42
xref: uniprot A0A2I3RPI4 411
organism: Pan troglodytes

uniprot C3YYJ8 827
type: UnificationXref
id: C3YYJ8
db: uniprot

PTHR24027:SF319
type: RelationshipXref
id: PTHR24027:SF319
db: PANTHER Family
relationship type: By Homology

Y654 betacatenin s3 a16 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y654
feature location: Y654 betacatenin s3 a16 rs1 Y654
comment: MODIFICATION_RESIDUE_ANGLE=3.3479165476195107
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=Y654

Uncharacterized protein
type: ProteinReference
xref: uniprot F6R9F4 247
xref: PTHR11937:SF446
organism: Monodelphis domestica

uniprot F7DQK7 262
type: UnificationXref
id: F7DQK7
db: uniprot

Cadherin s19 sa13 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Cadherin
stoichiometric coefficient: 1.0

PTHR24418:SF44
type: RelationshipXref
id: PTHR24418:SF44
db: PANTHER Family
relationship type: By Homology

uniprot Q7Q3K5 661
type: UnificationXref
id: Q7Q3K5
db: uniprot

Actin, indirect flight muscle
type: ProteinReference
xref: PTHR11937:SF397
xref: uniprot P83967 338
organism: Drosophila melanogaster

uniprot A0A1D5RE70 811
type: UnificationXref
id: A0A1D5RE70
db: uniprot

uniprot F1A175 239
type: UnificationXref
id: F1A175
db: uniprot

uniprot P12931 153
type: UnificationXref
id: P12931
db: uniprot

betacatenin s5 sa1 rs5
type: ModificationFeature
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=4.653633157668967
comment: MODIFICATION_RESIDUE_NAME=

PTHR24027:SF300
type: RelationshipXref
id: PTHR24027:SF300
db: PANTHER Family
relationship type: By Homology

betacatenin
type: Protein
entity reference: betacatenin
feature: S betacatenin s93 a132 rs4
feature: T112 betacatenin s93 a132 rs3
feature: betacatenin s93 a132 rs5
feature: Y142 betacatenin s93 a132 rs2
feature: Y654 betacatenin s93 a132 rs1
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

Actin-related protein 2-A
type: ProteinReference
xref: uniprot Q7SXW6 376
xref: PTHR11937:SF149
organism: Danio rerio

CATALYSIS
type: Catalysis
controlled: HETERODIMER_ASSOCIATION_LEFT__Complex__Cadherin_betacatenin_-_Complex__alphacatenin_F_actin_-RIGHT__Complex__Cadherin_Cadherin__betacatenin_alphacatenin__F_actin_-_r17
controller: Casein kinase II

uniprot A2G1K5 173
type: UnificationXref
id: A2G1K5
db: uniprot

uniprot Q9Y5I1 779
type: UnificationXref
id: Q9Y5I1
db: uniprot

PTHR24418:SF53
type: RelationshipXref
id: PTHR24418:SF53
db: PANTHER Family
relationship type: By Homology

uniprot Q62956 144
type: UnificationXref
id: Q62956
db: uniprot

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF93
xref: uniprot H2RAM0 889
organism: Pan troglodytes

Protein Wnt
type: ProteinReference
xref: uniprot A4ZGP0 818
xref: PTHR12027:SF82
organism: Xenopus tropicalis

PARTICIPANT STOICHIOMETRY r49 1160
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

Protein Wnt
type: ProteinReference
xref: uniprot F7FK62 872
xref: PTHR12027:SF94
organism: Ornithorhynchus anatinus

uniprot A9TVP1 197
type: UnificationXref
id: A9TVP1
db: uniprot

Strongylocentrotus purpuratus
type: BioSource
xref: ncbitaxon 7668 83

Uncharacterized protein
type: ProteinReference
xref: uniprot F6QHF6 798
organism: Macaca mulatta

Uncharacterized protein
type: ProteinReference
xref: uniprot F6PWM3 994
xref: PTHR11309:SF22
organism: Monodelphis domestica

S betacatenin s111 a157 rs4
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY S
feature location: S betacatenin s111 a157 rs4 S
comment: MODIFICATION_RESIDUE_NAME=S
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=1.6575346654708816

Protocadherin alpha-4
type: ProteinReference
xref: uniprot Q9UN74 737
xref: PTHR24028:SF82
organism: Homo sapiens

Protocadherin alpha-6
type: ProteinReference
xref: PTHR24028:SF265
xref: uniprot Q9UN73 736
organism: Homo sapiens

uniprot Q8K4C8 1043
type: UnificationXref
id: Q8K4C8
db: uniprot

Protocadherin alpha-7
type: ProteinReference
xref: uniprot Q9UN72 735
xref: PTHR24028:SF225
organism: Homo sapiens

uniprot Q90763 682
type: UnificationXref
id: Q90763
db: uniprot

Protocadherin gamma-B4
type: ProteinReference
xref: PTHR24028:SF117
xref: uniprot Q9UN71 734
organism: Homo sapiens

uniprot Q28GC2 80
type: UnificationXref
id: Q28GC2
db: uniprot

uniprot F1QDL0 787
type: UnificationXref
id: F1QDL0
db: uniprot

Cadherin-13
type: ProteinReference
xref: uniprot Q9WTR5 745
xref: PTHR24027:SF80
organism: Mus musculus

Protocadherin gamma-C3
type: ProteinReference
xref: PTHR24028:SF70
xref: uniprot Q9UN70 733
organism: Homo sapiens

betacatenin
type: Protein
entity reference: betacatenin
feature: Y654 betacatenin s119 a170 rs1
feature: Y142 betacatenin s119 a170 rs2
feature: S betacatenin s119 a170 rs4
feature: betacatenin s119 a170 rs5
feature: T112 betacatenin s119 a170 rs3
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

uniprot J9NZJ2 890
type: UnificationXref
id: J9NZJ2
db: uniprot

TRANSPORT_LEFT__betacatenin-RIGHT__betacatenin-_r47
type: TransportWithBiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: TRANSPORT
participant stoichiometry: PARTICIPANT STOICHIOMETRY r47 1166
participant stoichiometry: PARTICIPANT STOICHIOMETRY r47 1167
left: betacatenin
interaction type: TRANSPORT
right: betacatenin

Alpha-cardiac actin
type: ProteinReference
xref: PTHR11937:SF176
xref: uniprot F7F210 264
organism: Macaca mulatta

uniprot C3XYC6 214
type: UnificationXref
id: C3XYC6
db: uniprot

Y654 betacatenin s5 sa1 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y654
feature location: Y654 betacatenin s5 sa1 rs1 Y654
comment: MODIFICATION_RESIDUE_ANGLE=3.3479165476195107
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=Y654

uniprot H2R2U1 75
type: UnificationXref
id: H2R2U1
db: uniprot

Cadherin-related family member 1
type: ProteinReference
xref: uniprot Q91XU7 687
xref: PTHR24028:SF263
organism: Rattus norvegicus

TRANSPORT_LEFT__betacatenin-RIGHT__betacatenin-_r48
type: TransportWithBiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: TRANSPORT
participant stoichiometry: PARTICIPANT STOICHIOMETRY r48 1165
participant stoichiometry: PARTICIPANT STOICHIOMETRY r48 1164
left: betacatenin
interaction type: TRANSPORT
right: betacatenin

actin, muscle-like
type: ProteinReference
xref: uniprot A0A1W2WEN5 166
organism: Ciona intestinalis

Receptor tyrosine-protein kinase erbB-4
type: ProteinReference
xref: PTHR24416:SF90
xref: uniprot Q61527 142
organism: Mus musculus

TRANSPORT_LEFT__betacatenin-RIGHT__betacatenin-_r49
type: TransportWithBiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: TRANSPORT
participant stoichiometry: PARTICIPANT STOICHIOMETRY r49 1159
participant stoichiometry: PARTICIPANT STOICHIOMETRY r49 1160
left: betacatenin
interaction type: TRANSPORT
right: betacatenin

uniprot P04426 902
type: UnificationXref
id: P04426
db: uniprot

Protocadherin alpha-12
type: ProteinReference
xref: uniprot Q9UN75 738
xref: PTHR24028:SF76
organism: Homo sapiens

Receptor tyrosine-protein kinase erbB-3
type: ProteinReference
xref: PTHR24416:SF88
xref: uniprot Q61526 141
organism: Mus musculus

uniprot Q9Y5H6 774
type: UnificationXref
id: Q9Y5H6
db: uniprot

uniprot A0A2I3SDT1 414
type: UnificationXref
id: A0A2I3SDT1
db: uniprot

AGAP008871-PA (Fragment)
type: ProteinReference
xref: uniprot Q7PWS3 1039
xref: PTHR11309:SF23
organism: Anopheles gambiae

Actin, alpha, cardiac muscle 1a
type: ProteinReference
xref: PTHR11937:SF150
xref: uniprot F1RCB6 242
organism: Danio rerio

TRANSPORT_LEFT__betacatenin-RIGHT__betacatenin-_r52
type: TransportWithBiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: TRANSPORT
participant stoichiometry: PARTICIPANT STOICHIOMETRY r52 1145
participant stoichiometry: PARTICIPANT STOICHIOMETRY r52 1144
left: betacatenin
interaction type: TRANSPORT
right: betacatenin

Casein kinase 2, alpha prime polypeptide a
type: ProteinReference
xref: PTHR24054:SF34
xref: uniprot Q7ZU33 63
organism: Danio rerio

TRANSPORT_LEFT__betacatenin-RIGHT__betacatenin-_r51
type: TransportWithBiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: TRANSPORT
participant stoichiometry: PARTICIPANT STOICHIOMETRY r51 1150
participant stoichiometry: PARTICIPANT STOICHIOMETRY r51 1149
left: betacatenin
interaction type: TRANSPORT
right: betacatenin

PARTICIPANT STOICHIOMETRY r49 1159
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

Actin
type: ProteinReference
xref: uniprot Q67G20 362
xref: PTHR11937:SF474
organism: Oryza sativa

PCDH18 isoform 2
type: ProteinReference
xref: uniprot H2R198 575
xref: PTHR24028:SF9
organism: Pan troglodytes

PTHR10913:SF13
type: RelationshipXref
id: PTHR10913:SF13
db: PANTHER Family
relationship type: By Homology

PTHR11937:SF389
type: RelationshipXref
id: PTHR11937:SF389
db: PANTHER Family
relationship type: By Homology

Protein Wnt-5b
type: ProteinReference
xref: uniprot Q92050 954
xref: PTHR12027:SF87
organism: Danio rerio

uniprot Q9W7C0 117
type: UnificationXref
id: Q9W7C0
db: uniprot

PTHR11937:SF387
type: RelationshipXref
id: PTHR11937:SF387
db: PANTHER Family
relationship type: By Homology

uniprot Q9UN73 736
type: UnificationXref
id: Q9UN73
db: uniprot

Fat protein
type: ProteinReference
xref: PTHR24026:SF89
xref: uniprot P73089 614
organism: Synechocystis

Protein Wnt
type: ProteinReference
xref: uniprot E2RDT2 844
xref: PTHR12027:SF94
organism: Canis lupus familiaris

Casein kinase II subunit alpha'
type: ProteinReference
xref: PTHR24054:SF34
xref: uniprot F1MJ55 25
organism: Bos taurus

uniprot Q8CFX3 670
type: UnificationXref
id: Q8CFX3
db: uniprot

uniprot Q2QL96 942
type: UnificationXref
id: Q2QL96
db: uniprot

uniprot J9P5H0 892
type: UnificationXref
id: J9P5H0
db: uniprot

Frizzled-4
type: ProteinReference
xref: PTHR11309:SF23
xref: uniprot Q61088 1033
organism: Mus musculus

uniprot P45891 297
type: UnificationXref
id: P45891
db: uniprot

Frizzled-6
type: ProteinReference
xref: PTHR11309:SF75
xref: uniprot Q61089 1034
organism: Mus musculus

Protein Wnt-2
type: ProteinReference
xref: PTHR12027:SF86
xref: uniprot Q92048 953
organism: Danio rerio

Frizzled-3
type: ProteinReference
xref: PTHR11309:SF22
xref: uniprot Q61086 1032
organism: Mus musculus

uniprot Q9Y5G6 765
type: UnificationXref
id: Q9Y5G6
db: uniprot

Cadherin-19
type: ProteinReference
xref: uniprot Q9H159 713
xref: PTHR24027:SF323
organism: Homo sapiens

Protocadherin alpha-C1
type: ProteinReference
xref: uniprot Q9H158 712
xref: PTHR24028:SF153
organism: Homo sapiens

Uncharacterized protein
type: ProteinReference
xref: PTHR24028:SF46
xref: uniprot E2RM28 461
organism: Canis lupus familiaris

PTHR11937:SF397
type: RelationshipXref
id: PTHR11937:SF397
db: PANTHER Family
relationship type: By Homology

Dictyostelium discoideum
type: BioSource
xref: ncbitaxon 44689 281

uniprot A0A1D5QZ34 406
type: UnificationXref
id: A0A1D5QZ34
db: uniprot

Protocadherin 19
type: ProteinReference
xref: uniprot A0A0G2K8I5 396
xref: PTHR24028:SF40
organism: Rattus norvegicus

uniprot P78711 336
type: UnificationXref
id: P78711
db: uniprot

uniprot Q91Y00 695
type: UnificationXref
id: Q91Y00
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR10373:SF25
xref: uniprot F6U055 105
organism: Macaca mulatta

Trypanosoma brucei
type: BioSource
xref: ncbitaxon 185431 346

uniprot F7BBY2 521
type: UnificationXref
id: F7BBY2
db: uniprot

uniprot F1M6B6 471
type: UnificationXref
id: F1M6B6
db: uniprot

uniprot C3ZBE3 18
type: UnificationXref
id: C3ZBE3
db: uniprot

uniprot P24383 913
type: UnificationXref
id: P24383
db: uniprot

uniprot A8Y4Q9 193
type: UnificationXref
id: A8Y4Q9
db: uniprot

uniprot F6SDC9 250
type: UnificationXref
id: F6SDC9
db: uniprot

Actin, alpha sarcomeric/skeletal
type: ProteinReference
xref: PTHR11937:SF240
xref: uniprot Q6P8G3 369
organism: Xenopus tropicalis

Protocadherin beta 2
type: ProteinReference
xref: PTHR24028:SF281
xref: uniprot F1M7D0 473
organism: Rattus norvegicus

Catenin delta-1
type: ProteinReference
xref: uniprot P30999 803
organism: Mus musculus

uniprot Q91XZ7 693
type: UnificationXref
id: Q91XZ7
db: uniprot

Nematostella vectensis
type: BioSource
xref: ncbitaxon 45351 11

uniprot K7D8P4 38
type: UnificationXref
id: K7D8P4
db: uniprot

ncbitaxon 5786 237
type: UnificationXref
id: 5786
db: ncbitaxon

Y142 betacatenin s119 a170 rs2
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Y142
feature location: Y142 betacatenin s119 a170 rs2 Y142
comment: MODIFICATION_RESIDUE_NAME=Y142
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=2.893781136851091

Protocadherin-19 isoform c
type: ProteinReference
xref: uniprot F6USP1 501
xref: PTHR24028:SF40
organism: Macaca mulatta

Uncharacterized protein
type: ProteinReference
xref: uniprot F7FZG1 539
xref: PTHR24027:SF84
organism: Macaca mulatta

PARTICIPANT STOICHIOMETRY r12 1175
type: Stoichiometry
physical entity: Fer
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r12 1176
type: Stoichiometry
physical entity: Fer
stoichiometric coefficient: 1.0

PTHR10373:SF25
type: RelationshipXref
id: PTHR10373:SF25
db: PANTHER Family
relationship type: By Homology

uniprot W4Y969 392
type: UnificationXref
id: W4Y969
db: uniprot

uniprot A0A2I3REF9 409
type: UnificationXref
id: A0A2I3REF9
db: uniprot

CDH1 isoform 1
type: ProteinReference
xref: PTHR24027:SF319
xref: uniprot A0A2J8Q404 426
organism: Pan troglodytes

S T Cadherin s19 sa13 rs2
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY S T
feature location: S T Cadherin s19 sa13 rs2 S T
modification type: phosphorylated residue
comment: MODIFICATION_RESIDUE_NAME=S/T
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=0.09

uniprot A7MB46 436
type: UnificationXref
id: A7MB46
db: uniprot

uniprot E2RDT2 844
type: UnificationXref
id: E2RDT2
db: uniprot

uniprot Q9YH60 1089
type: UnificationXref
id: Q9YH60
db: uniprot

Frizzled
type: Protein
entity reference: Frizzled
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

PTHR10373:SF11
type: RelationshipXref
id: PTHR10373:SF11
db: PANTHER Family
relationship type: By Homology

uniprot P53501 306
type: UnificationXref
id: P53501
db: uniprot

uniprot P97291 616
type: UnificationXref
id: P97291
db: uniprot

Frizzled-8
type: ProteinReference
xref: uniprot Q61091 1036
xref: PTHR11309:SF90
organism: Mus musculus

Frizzled-7
type: ProteinReference
xref: uniprot Q61090 1035
xref: PTHR11309:SF31
organism: Mus musculus

ncbitaxon 559292 308
type: UnificationXref
id: 559292
db: ncbitaxon

uniprot O88277 583
type: UnificationXref
id: O88277
db: uniprot

uniprot F1MGM1 989
type: UnificationXref
id: F1MGM1
db: uniprot

uniprot C3XYC2 210
type: UnificationXref
id: C3XYC2
db: uniprot

uniprot P06494 135
type: UnificationXref
id: P06494
db: uniprot

P120 s34 sa19 rs1
type: ModificationFeature
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=
comment: MODIFICATION_RESIDUE_ANGLE=3.14

uniprot P55286 605
type: UnificationXref
id: P55286
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot H3FCG4 273
organism: Pristionchus pacificus

uniprot Q7PPN5 145
type: UnificationXref
id: Q7PPN5
db: uniprot

uniprot P35222 76
type: UnificationXref
id: P35222
db: uniprot

T112 betacatenin s13 sa5 rs3
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY T112
feature location: T112 betacatenin s13 sa5 rs3 T112
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=T112
comment: MODIFICATION_RESIDUE_ANGLE=-0.0

uniprot Q5DRD6 637
type: UnificationXref
id: Q5DRD6
db: uniprot

Protocadherin beta 5
type: ProteinReference
xref: uniprot Q91XZ5 691
xref: PTHR24028:SF55
organism: Mus musculus

uniprot A0A0G2K3B7 805
type: UnificationXref
id: A0A0G2K3B7
db: uniprot

Protocadherin beta-6
type: ProteinReference
xref: uniprot Q91XZ4 690
xref: PTHR24028:SF90
organism: Mus musculus

TCF/LEF
type: ProteinReference
xref: P00465
standard name: T-cell factor/lymphoid enhancer factor
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Cadherin signaling pathway.PROTEIN.GENERIC.TCF_slash_LEF
comment: ENTITY_REFERENCE_NOTES=
member entity reference: Uncharacterized protein
member entity reference: Transcription factor 7-like 1-A
member entity reference: Transcription factor 7-like 1
member entity reference: Transcription factor 7-like 2
member entity reference: Lymphoid enhancer-binding factor 1
member entity reference: Lymphoid enhancer binding factor 1
member entity reference: Lymphocyte enhancer binding factor 1
member entity reference: TCF7L1 isoform 2
member entity reference: Transcription factor 7 like 1

uniprot Q9HCU4 718
type: UnificationXref
id: Q9HCU4
db: uniprot

Protocadherin beta-8
type: ProteinReference
xref: uniprot Q91XZ2 689
xref: PTHR24028:SF90
organism: Mus musculus

uniprot P09324 1073
type: UnificationXref
id: P09324
db: uniprot

uniprot P51028 928
type: UnificationXref
id: P51028
db: uniprot

ncbitaxon 321614 268
type: UnificationXref
id: 321614
db: ncbitaxon

Protocadherin beta 22
type: ProteinReference
xref: uniprot Q91XZ8 694
xref: PTHR24028:SF97
organism: Mus musculus

Protocadherin beta 3
type: ProteinReference
xref: PTHR24028:SF118
xref: uniprot Q91XZ7 693
organism: Mus musculus

Protocadherin beta 4
type: ProteinReference
xref: uniprot Q91XZ6 692
xref: PTHR24028:SF87
organism: Mus musculus

Putative actin-5
type: ProteinReference
xref: PTHR11937:SF411
xref: uniprot Q8RYC2 384
organism: Arabidopsis thaliana

Receptor protein-tyrosine kinase
type: ProteinReference
xref: uniprot A0A2I3RYF9 122
xref: PTHR24416:SF91
organism: Pan troglodytes

uniprot E2RHZ1 20
type: UnificationXref
id: E2RHZ1
db: uniprot

uniprot P22726 910
type: UnificationXref
id: P22726
db: uniprot

STATE_TRANSITION
type: InteractionVocabulary

uniprot F7D4J8 868
type: UnificationXref
id: F7D4J8
db: uniprot

TRANSPORT
type: InteractionVocabulary

uniprot I2CYF0 274
type: UnificationXref
id: I2CYF0
db: uniprot

uniprot Q9R0T4 726
type: UnificationXref
id: Q9R0T4
db: uniprot

uniprot F6UA54 252
type: UnificationXref
id: F6UA54
db: uniprot

uniprot A0A1D5P6T7 398
type: UnificationXref
id: A0A1D5P6T7
db: uniprot

PTHR11937:SF359
type: RelationshipXref
id: PTHR11937:SF359
db: PANTHER Family
relationship type: By Homology

Protein Wnt
type: ProteinReference
xref: uniprot H2Q4F7 883
xref: PTHR12027:SF7
organism: Pan troglodytes

Actin
type: ProteinReference
xref: PTHR11937:SF387
xref: uniprot A7ETS6 177
organism: Sclerotinia sclerotiorum

uniprot Q3ZC07 347
type: UnificationXref
id: Q3ZC07
db: uniprot

uniprot Q38E94 345
type: UnificationXref
id: Q38E94
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F7A659 1003
xref: PTHR11309:SF31
organism: Monodelphis domestica

Cadherin-related tumor suppressor
type: ProteinReference
xref: PTHR24026:SF76
xref: uniprot P33450 597
organism: Drosophila melanogaster

PARTICIPANT STOICHIOMETRY r48 1165
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

uniprot D3ZRN3 228
type: UnificationXref
id: D3ZRN3
db: uniprot

uniprot F7ACT4 1084
type: UnificationXref
id: F7ACT4
db: uniprot

Protocadherin-11 X-linked
type: ProteinReference
xref: PTHR24028:SF254
xref: uniprot Q71M42 650
organism: Pan troglodytes

uniprot Q04736 1075
type: UnificationXref
id: Q04736
db: uniprot

uniprot Q61091 1036
type: UnificationXref
id: Q61091
db: uniprot

uniprot P20399 296
type: UnificationXref
id: P20399
db: uniprot

PARTICIPANT STOICHIOMETRY r48 1164
type: Stoichiometry
physical entity: betacatenin
stoichiometric coefficient: 1.0

P120
type: Protein
entity reference: P120
feature: P120 s121 a174 rs1
cellular location: cytoplasm
comment: SPECIES_TYPE=PROTEIN

PTHR10373:SF32
type: RelationshipXref
id: PTHR10373:SF32
db: PANTHER Family
relationship type: By Homology

uniprot P58365 611
type: UnificationXref
id: P58365
db: uniprot

uniprot G5EG05 880
type: UnificationXref
id: G5EG05
db: uniprot

uniprot P39688 94
type: UnificationXref
id: P39688
db: uniprot

uniprot P68035 330
type: UnificationXref
id: P68035
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F1A175 239
xref: PTHR11937:SF387
organism: Dictyostelium purpureum

uniprot P00533 132
type: UnificationXref
id: P00533
db: uniprot

betacatenin s13 sa5 rs5
type: ModificationFeature
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=4.653633157668967
comment: MODIFICATION_RESIDUE_NAME=

Protocadherin-20
type: ProteinReference
xref: uniprot Q8N6Y1 671
xref: PTHR24028:SF260
organism: Homo sapiens

uniprot F6W1H1 508
type: UnificationXref
id: F6W1H1
db: uniprot

uniprot Q9UN75 738
type: UnificationXref
id: Q9UN75
db: uniprot

PTHR11937:SF362
type: RelationshipXref
id: PTHR11937:SF362
db: PANTHER Family
relationship type: By Homology

PTHR24028:SF144
type: RelationshipXref
id: PTHR24028:SF144
db: PANTHER Family
relationship type: By Homology

uniprot Q62844 97
type: UnificationXref
id: Q62844
db: uniprot

PTHR24028:SF146
type: RelationshipXref
id: PTHR24028:SF146
db: PANTHER Family
relationship type: By Homology

Protocadherin 18
type: ProteinReference
xref: uniprot Q8VHR0 678
xref: PTHR24028:SF9
organism: Mus musculus

PTHR24028:SF148
type: RelationshipXref
id: PTHR24028:SF148
db: PANTHER Family
relationship type: By Homology

uniprot F6R9F4 247
type: UnificationXref
id: F6R9F4
db: uniprot

uniprot H2QB90 562
type: UnificationXref
id: H2QB90
db: uniprot

Protein Wnt
type: ProteinReference
xref: uniprot F7HKD3 877
xref: PTHR12027:SF94
organism: Macaca mulatta

Phaeosphaeria nodorum
type: BioSource
xref: ncbitaxon 321614 268

uniprot Q9UQB3 804
type: UnificationXref
id: Q9UQB3
db: uniprot

Cadherin-related family member 2
type: ProteinReference
xref: PTHR24026:SF75
xref: uniprot Q9BYE9 709
organism: Homo sapiens

Uncharacterized protein
type: ProteinReference
xref: PTHR24028:SF46
xref: uniprot F1MEC8 478
organism: Bos taurus

Actin, cytoplasmic 1
type: ProteinReference
xref: uniprot Q6NVA9 366
xref: PTHR11937:SF477
organism: Xenopus tropicalis

Protein tyrosine phosphatase non-receptor type 1
type: ProteinReference
xref: uniprot F1QDL0 787
organism: Danio rerio

uniprot Q9Z0M3 784
type: UnificationXref
id: Q9Z0M3
db: uniprot

uniprot F6XUZ7 865
type: UnificationXref
id: F6XUZ7
db: uniprot

Actin
type: ProteinReference
xref: PTHR11937:SF248
xref: uniprot Q75HX0 374
organism: Oryza sativa

Protocadherin 1
type: ProteinReference
xref: uniprot Q8CFX3 670
xref: PTHR24028:SF247
organism: Mus musculus

Frizzled-5
type: ProteinReference
xref: uniprot Q9EQD0 1046
xref: PTHR11309:SF136
organism: Mus musculus

PTHR24028:SF150
type: RelationshipXref
id: PTHR24028:SF150
db: PANTHER Family
relationship type: By Homology

uniprot Q9Y5H1 769
type: UnificationXref
id: Q9Y5H1
db: uniprot

uniprot A0A2I3RE49 408
type: UnificationXref
id: A0A2I3RE49
db: uniprot

Protein Wnt
type: ProteinReference
xref: PTHR12027:SF78
xref: uniprot Q4JLT0 945
organism: Danio rerio

Protein dachsous
type: ProteinReference
xref: PTHR24026:SF100
xref: uniprot Q24292 625
organism: Drosophila melanogaster

uniprot P56705 933
type: UnificationXref
id: P56705
db: uniprot

PTHR24028:SF153
type: RelationshipXref
id: PTHR24028:SF153
db: PANTHER Family
relationship type: By Homology

DE-cadherin
type: ProteinReference
xref: PTHR24026:SF108
xref: uniprot Q24298 626
organism: Drosophila melanogaster

uniprot A0JNB0 85
type: UnificationXref
id: A0JNB0
db: uniprot

Monosiga brevicollis
type: BioSource
xref: ncbitaxon 81824 202

uniprot P49841 1087
type: UnificationXref
id: P49841
db: uniprot

CDH19 isoform 2
type: ProteinReference
xref: uniprot A0A2I3SHA1 415
xref: PTHR24027:SF323
organism: Pan troglodytes

uniprot Q93097 955
type: UnificationXref
id: Q93097
db: uniprot