crotono-betaine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__H2O-_crotonobetainyl_CoA-RIGHT__L_carnitine_CoA-_r3
controller: L-carnitine dehydratase

reduced acceptor
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

L-carnitine dehydratase
type: ProteinReference
xref: P02864
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: L-carnitine dehydratase Synonym: Synonym not specified Accession: P02864
comment: ENTITY_REFERENCE_ID_DESC=Coenzyme A linked carnitine metabolism.PROTEIN.GENERIC.L-carnitine dehydratase
member entity reference: LP04613p
member entity reference: Succinate--hydroxymethylglutarate CoA-transferase
member entity reference: LOC100125578 protein

H2O
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__L_carnitine_CoA-RIGHT__D_cartinyl_CoA-_r4
controller: Carnitine racemase

crotonobetainyl-CoA
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

STATE_TRANSITION
type: InteractionVocabulary

STATE_TRANSITION
type: RelationshipTypeVocabulary

STATE_TRANSITION_LEFT__L_carnitine_CoA-RIGHT__D_cartinyl_CoA-_r4
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 25
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 24
left: L-carnitine-CoA
interaction type: STATE_TRANSITION
right: D-cartinyl-CoA

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__L_carnitine_CoA-RIGHT__CoA-_L_carnitine-_r6
controller: Carnitine-CoA ligase

Carnitine-CoA ligase
type: Protein
comment: SPECIES_TYPE=PROTEIN

Bos taurus
type: BioSource
xref: ncbitaxon 9913 3

Coenzyme A linked carnitine metabolism
type: Pathway
pathway component: STATE_TRANSITION_LEFT__crotono_betaine-_CoA-RIGHT__crotonobetainyl_CoA-_r1
pathway component: STATE_TRANSITION_LEFT__D_cartinyl_CoA-RIGHT__D_carnitine-_CoA-_r5
pathway component: STATE_TRANSITION_LEFT__reduced_acceptor-_crotonobetainyl_CoA-RIGHT__butyrobetainyl_CoA-_acceptor-_r2
pathway component: STATE_TRANSITION_LEFT__H2O-_crotonobetainyl_CoA-RIGHT__L_carnitine_CoA-_r3
pathway component: STATE_TRANSITION_LEFT__L_carnitine_CoA-RIGHT__CoA-_L_carnitine-_r6
pathway component: STATE_TRANSITION_LEFT__L_carnitine_CoA-RIGHT__D_cartinyl_CoA-_r4
xref: PANTHER Pathway P02732 1
comment: MODEL_NOTES=The degradation of the quaternary amine carnitine and its ligation with CoA which may function as a electron acceptor during anaerobic respiration. Website=www.biocyc.org/Ecoli/Pathways/ free text=Voet and Voet (textbook) Biochemistry

butyrobetainyl-CoA
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r5 22
type: Stoichiometry
physical entity: D-carnitine
stoichiometric coefficient: 1.0

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__reduced_acceptor-_crotonobetainyl_CoA-RIGHT__butyrobetainyl_CoA-_acceptor-_r2
controller: Crotonobetaine reductase

PARTICIPANT STOICHIOMETRY r5 21
type: Stoichiometry
physical entity: D-cartinyl-CoA
stoichiometric coefficient: 1.0

Crotonobetaine-CoA ligase
type: Protein
comment: SPECIES_TYPE=PROTEIN

uniprot A6QQD0 2
type: UnificationXref
id: A6QQD0
db: uniprot

ncbitaxon 10090 5
type: UnificationXref
id: 10090
db: ncbitaxon

Mus musculus
type: BioSource
xref: ncbitaxon 10090 5

uniprot Q7TNE1 4
type: UnificationXref
id: Q7TNE1
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__D_cartinyl_CoA-RIGHT__D_carnitine-_CoA-_r5
controller: Carnitine-CoA ligase

acceptor
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r4 25
type: Stoichiometry
physical entity: D-cartinyl-CoA
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r4 24
type: Stoichiometry
physical entity: L-carnitine-CoA
stoichiometric coefficient: 1.0

Drosophila melanogaster
type: BioSource
xref: ncbitaxon 7227 7

PANTHER Pathway P02732 1
type: UnificationXref
id: P02732
db: PANTHER Pathway

STATE_TRANSITION_LEFT__reduced_acceptor-_crotonobetainyl_CoA-RIGHT__butyrobetainyl_CoA-_acceptor-_r2
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 13
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 14
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 12
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 11
left: reduced acceptor
left: crotonobetainyl-CoA
interaction type: STATE_TRANSITION
right: acceptor
right: butyrobetainyl-CoA

PARTICIPANT STOICHIOMETRY r2 14
type: Stoichiometry
physical entity: acceptor
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r2 13
type: Stoichiometry
physical entity: butyrobetainyl-CoA
stoichiometric coefficient: 1.0

D-cartinyl-CoA
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

L-carnitine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

LP04613p
type: ProteinReference
xref: uniprot Q9VDL4 6
organism: Drosophila melanogaster

PARTICIPANT STOICHIOMETRY r2 12
type: Stoichiometry
physical entity: crotonobetainyl-CoA
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r2 11
type: Stoichiometry
physical entity: reduced acceptor
stoichiometric coefficient: 1.0

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__crotono_betaine-_CoA-RIGHT__crotonobetainyl_CoA-_r1
controller: Crotonobetaine-CoA ligase

Succinate--hydroxymethylglutarate CoA-transferase
type: ProteinReference
xref: uniprot Q7TNE1 4
organism: Mus musculus

STATE_TRANSITION_LEFT__crotono_betaine-_CoA-RIGHT__crotonobetainyl_CoA-_r1
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 16
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 15
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 17
left: crotono-betaine
left: CoA
interaction type: STATE_TRANSITION
right: crotonobetainyl-CoA

ncbitaxon 7227 7
type: UnificationXref
id: 7227
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r3 9
type: Stoichiometry
physical entity: crotonobetainyl-CoA
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r5 23
type: Stoichiometry
physical entity: CoA
stoichiometric coefficient: 1.0

L-carnitine dehydratase
type: Protein
entity reference: L-carnitine dehydratase
comment: SPECIES_TYPE=PROTEIN

PARTICIPANT STOICHIOMETRY r3 8
type: Stoichiometry
physical entity: H2O
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r3 10
type: Stoichiometry
physical entity: L-carnitine-CoA
stoichiometric coefficient: 1.0

STATE_TRANSITION_LEFT__L_carnitine_CoA-RIGHT__CoA-_L_carnitine-_r6
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 20
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 18
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 19
left: L-carnitine-CoA
interaction type: STATE_TRANSITION
right: CoA
right: L-carnitine

CoA
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r1 15
type: Stoichiometry
physical entity: crotono-betaine
stoichiometric coefficient: 1.0

P02864
type: UnificationXref
id: P02864
db: PANTHER Pathway Component

STATE_TRANSITION_LEFT__D_cartinyl_CoA-RIGHT__D_carnitine-_CoA-_r5
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 23
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 21
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 22
left: D-cartinyl-CoA
interaction type: STATE_TRANSITION
right: D-carnitine
right: CoA

LOC100125578 protein
type: ProteinReference
xref: uniprot A6QQD0 2
organism: Bos taurus

PARTICIPANT STOICHIOMETRY r1 16
type: Stoichiometry
physical entity: CoA
stoichiometric coefficient: 1.0

ncbitaxon 9913 3
type: UnificationXref
id: 9913
db: ncbitaxon

Crotonobetaine reductase
type: Protein
comment: SPECIES_TYPE=PROTEIN

L-carnitine-CoA
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r1 17
type: Stoichiometry
physical entity: crotonobetainyl-CoA
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r6 19
type: Stoichiometry
physical entity: CoA
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r6 18
type: Stoichiometry
physical entity: L-carnitine-CoA
stoichiometric coefficient: 1.0

STATE_TRANSITION_LEFT__H2O-_crotonobetainyl_CoA-RIGHT__L_carnitine_CoA-_r3
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 10
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 8
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 9
left: H2O
left: crotonobetainyl-CoA
interaction type: STATE_TRANSITION
right: L-carnitine-CoA

PARTICIPANT STOICHIOMETRY r6 20
type: Stoichiometry
physical entity: L-carnitine
stoichiometric coefficient: 1.0

Carnitine racemase
type: Protein
comment: SPECIES_TYPE=PROTEIN

D-carnitine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q9VDL4 6
type: UnificationXref
id: Q9VDL4
db: uniprot