Glyceraldehyde
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot F1PNI3 13
type: UnificationXref
id: F1PNI3
db: uniprot

Fructose-bisphosphate aldolase
type: ProteinReference
xref: PTHR11627:SF1
xref: uniprot A0A3Q1LMG1 6
organism: Bos taurus

PTHR11627:SF16
type: RelationshipXref
id: PTHR11627:SF16
db: PANTHER Family
relationship type: By Homology

uniprot H2QHL3 81
type: UnificationXref
id: H2QHL3
db: uniprot

Glucose
type: SmallMolecule
cellular location: Glycolysis c2
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q7KQL9 55
type: UnificationXref
id: Q7KQL9
db: uniprot

uniprot Q02974 84
type: UnificationXref
id: Q02974
db: uniprot

uniprot P51570 72
type: UnificationXref
id: P51570
db: uniprot

uniprot O08528 109
type: UnificationXref
id: O08528
db: uniprot

Galactose-1-phosphate uridylyltransferase
type: ProteinReference
xref: PTHR11943:SF1
xref: uniprot O33836 86
organism: Thermotoga maritima

uniprot H2QDW0 69
type: UnificationXref
id: H2QDW0
db: uniprot

uniprot Q5RKH2 76
type: UnificationXref
id: Q5RKH2
db: uniprot

Cryptococcus neoformans
type: BioSource
xref: ncbitaxon 214684 92

uniprot P05063 35
type: UnificationXref
id: P05063
db: uniprot

eco ECO:0000304 47
type: UnificationXref
id: ECO:0000304
db: eco

PTHR11627:SF20
type: RelationshipXref
id: PTHR11627:SF20
db: PANTHER Family
relationship type: By Homology

Galactokinase
type: ProteinReference
xref: uniprot Q9GKK4 78
xref: PTHR10457:SF6
organism: Canis lupus familiaris

Putative hexokinase YLR446W
type: ProteinReference
xref: uniprot Q06204 114
xref: PTHR19443:SF72
organism: Saccharomyces cerevisiae

uniprot P09972 44
type: UnificationXref
id: P09972
db: uniprot

Galactose-1-phosphate uridylyltransferase
type: ProteinReference
xref: uniprot P0CN76 91
xref: PTHR11943:SF1
organism: Cryptococcus neoformans

Thermotoga maritima
type: BioSource
xref: ncbitaxon 243274 87

PTHR19443:SF72
type: RelationshipXref
id: PTHR19443:SF72
db: PANTHER Family
relationship type: By Homology

eco ECO:0000501 115
type: UnificationXref
id: ECO:0000501
db: eco

Mus musculus
type: BioSource
xref: ncbitaxon 10090 11

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Galactose_1_phosphate-RIGHT__Glucose_1_phosphate-_r51
controller: Hexose 1-P uridyltransferase

UDP Galactose
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r53 126
type: Stoichiometry
physical entity: UDP Glucose
stoichiometric coefficient: 1.0

TRUNCATION_LEFT__Fructose_1,6_phosphate-RIGHT__Dihydroxyacetone_3_P-_Glyceraldehyde_3_P-_r39
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: TRUNCATION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r39 152
participant stoichiometry: PARTICIPANT STOICHIOMETRY r39 151
participant stoichiometry: PARTICIPANT STOICHIOMETRY r39 150
left: Fructose 1,6-phosphate
interaction type: TRUNCATION
right: Dihydroxyacetone 3-P
right: Glyceraldehyde 3-P

PARTICIPANT STOICHIOMETRY r53 125
type: Stoichiometry
physical entity: UDP Galactose
stoichiometric coefficient: 1.0

Saccharomyces cerevisiae
type: BioSource
xref: ncbitaxon 559292 90

Phosphotransferase
type: ProteinReference
xref: PTHR19443:SF16
xref: uniprot Q27648 116
organism: Entamoeba histolytica

Drosophila melanogaster
type: BioSource
xref: ncbitaxon 7227 41

Hexokinase-1
type: ProteinReference
xref: uniprot P17710 110
organism: Mus musculus

Entamoeba histolytica
type: BioSource
xref: ncbitaxon 5759 117

By Homology
type: RelationshipTypeVocabulary

uniprot F6WHL1 23
type: UnificationXref
id: F6WHL1
db: uniprot

ncbitaxon 9913 7
type: UnificationXref
id: 9913
db: ncbitaxon

ISS
type: EvidenceCodeVocabulary
xref: eco ECO:0000250 4

Sorbitol
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Fructose-bisphosphate aldolase B
type: ProteinReference
xref: PTHR11627:SF2
xref: uniprot Q91Y97 59
organism: Mus musculus

Hexokinase-2
type: ProteinReference
xref: uniprot P27881 112
organism: Rattus norvegicus

Galactokinase
type: ProteinReference
xref: PTHR10457:SF6
xref: uniprot A6H768 66
organism: Bos taurus

UDP Glucose 4 epimerase
type: ProteinReference
xref: P02965
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: UDP Glucose 4 epimerase Synonym: Synonym not specified Accession: P02965
comment: ENTITY_REFERENCE_ID_DESC=Fructose galactose metabolism.PROTEIN.GENERIC.UDP Glucose_br_4 epimerase
member entity reference: UDP-glucose 4-epimerase
member entity reference: Bifunctional protein GAL10
member entity reference: UDP-galactose 4-epimerase

ncbitaxon 7227 41
type: UnificationXref
id: 7227
db: ncbitaxon

Fructose-bisphosphate aldolase
type: ProteinReference
xref: uniprot H2QCI1 28
xref: PTHR11627:SF3
organism: Pan troglodytes

uniprot Q386N7 100
type: UnificationXref
id: Q386N7
db: uniprot

Galactose-1-phosphate uridylyltransferase
type: ProteinReference
xref: uniprot P07902 88
xref: PTHR11943:SF1
organism: Homo sapiens

uniprot F7E7R1 26
type: UnificationXref
id: F7E7R1
db: uniprot

uniprot A0A3Q1M891 65
type: UnificationXref
id: A0A3Q1M891
db: uniprot

ncbitaxon 8364 27
type: UnificationXref
id: 8364
db: ncbitaxon

uniprot P07341 38
type: UnificationXref
id: P07341
db: uniprot

Pyruvate
type: SmallMolecule
cellular location: Glycolysis c2
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r40 158
type: Stoichiometry
physical entity: Pyruvate
stoichiometric coefficient: 1.0

PTHR11627:SF44
type: RelationshipXref
id: PTHR11627:SF44
db: PANTHER Family
relationship type: By Homology

PARTICIPANT STOICHIOMETRY r40 157
type: Stoichiometry
physical entity: Glyceraldehyde 3-P
stoichiometric coefficient: 1.0

uniprot P05062 34
type: UnificationXref
id: P05062
db: uniprot

PTHR11627:SF42
type: RelationshipXref
id: PTHR11627:SF42
db: PANTHER Family
relationship type: By Homology

ncbitaxon 13616 18
type: UnificationXref
id: 13616
db: ncbitaxon

uniprot Q59VY8 74
type: UnificationXref
id: Q59VY8
db: uniprot

Plasmodium falciparum
type: BioSource
xref: ncbitaxon 36329 56

Fructose-bisphosphate aldolase
type: ProteinReference
xref: PTHR11627:SF3
xref: uniprot A0A3S5ZPB0 8
organism: Bos taurus

Monodelphis domestica
type: BioSource
xref: ncbitaxon 13616 18

ncbitaxon 9031 39
type: UnificationXref
id: 9031
db: ncbitaxon

N-acetylgalactosamine kinase
type: ProteinReference
xref: uniprot Q01415 73
organism: Homo sapiens

UDP-glucose 4-epimerase
type: ProteinReference
xref: uniprot Q8R059 102
organism: Mus musculus

Hexokinase 2
type: ProteinReference
xref: uniprot H2QI73 107
organism: Pan troglodytes

Ketohexokinase
type: ProteinReference
xref: PTHR43085:SF1
xref: uniprot Q02974 84
organism: Rattus norvegicus

ncbitaxon 243274 87
type: UnificationXref
id: 243274
db: ncbitaxon

Galactose-1-phosphate uridylyltransferase
type: ProteinReference
xref: PTHR11943:SF1
xref: uniprot E2RB65 85
organism: Canis lupus familiaris

uniprot P04397 96
type: UnificationXref
id: P04397
db: uniprot

Galactokinase 1
type: ProteinReference
xref: uniprot H2QDW0 69
xref: PTHR10457:SF6
organism: Pan troglodytes

Fructose-bisphosphate aldolase, chloroplastic
type: ProteinReference
xref: uniprot Q40677 49
xref: PTHR11627:SF16
organism: Oryza sativa

IEP
type: EvidenceCodeVocabulary
xref: eco ECO:0000270 29

Galactokinase
type: ProteinReference
xref: PTHR10457:SF6
xref: uniprot Q9R0N0 79
organism: Mus musculus

Fructose-bisphosphate aldolase
type: ProteinReference
xref: uniprot A0A2I3SKK2 2
xref: PTHR11627:SF2
organism: Pan troglodytes

Uncharacterized protein
type: ProteinReference
xref: PTHR43085:SF1
xref: uniprot F7GPR3 80
organism: Macaca mulatta

uniprot P07902 88
type: UnificationXref
id: P07902
db: uniprot

uniprot P00884 30
type: UnificationXref
id: P00884
db: uniprot

Fructose galactose metabolism
type: Pathway
pathway component: STATE_TRANSITION_LEFT__Galactose_1_phosphate-RIGHT__Glucose_1_phosphate-_r51
pathway component: STATE_TRANSITION_LEFT__Glucose-RIGHT__Glucose_6_phosphate-_r5
pathway component: STATE_TRANSITION_LEFT__ATP-_Glyceraldehyde-RIGHT__ADP-_Glyceraldehyde_3_P-_r49
pathway component: STATE_TRANSITION_LEFT__NADH__PLUS__H_PLUS_-_Glyceraldehyde-RIGHT__NAD_PLUS_-_Glycerol-_r46
pathway component: STATE_TRANSITION_LEFT__Glucose_6_phosphate-RIGHT__Fructose_6_phosphate-_r6
pathway component: KNOWN_TRANSITION_OMITTED_LEFT__Glyceraldehyde_3_P-RIGHT__Pyruvate-_r40
pathway component: STATE_TRANSITION_LEFT__UDP_Glucose-RIGHT__UDP_Galactose-_r54
pathway component: STATE_TRANSITION_LEFT__Fructose_6_phosphate-RIGHT__Fructose_1,6_phosphate-_r38
pathway component: STATE_TRANSITION_LEFT__Glucose_1_phosphate-RIGHT__Glucose_6_phosphate-_r52
pathway component: TRUNCATION_LEFT__Fructose_1,6_phosphate-RIGHT__Dihydroxyacetone_3_P-_Glyceraldehyde_3_P-_r39
pathway component: STATE_TRANSITION_LEFT__UDP_Galactose-RIGHT__UDP_Glucose-_r53
pathway component: STATE_TRANSITION_LEFT__Sorbitol-RIGHT__Fructose-_r41
pathway component: STATE_TRANSITION_LEFT__ATP-_Fructose-RIGHT__ADP-_Fructose_1_Phosphate-_r44
pathway component: STATE_TRANSITION_LEFT__Galactose-_ATP-RIGHT__ADP-_Galactose_1_phosphate-_r50
pathway component: TRUNCATION_LEFT__Fructose_1_Phosphate-RIGHT__Dihydroxyacetone_3_P-_Glyceraldehyde-_r48
xref: PANTHER Pathway P02744 1
comment: MODEL_NOTES=The main pathway for the degradation of fructose in the liver is via glycolysis. Before it can enter glycolysis, however, fructose has to unergo a series of enzymatic catalysis reactions, comprising a major part of fructose metabolism pathway. Galactose is also metabolized in the liver. The entry of galactose into glycolysis is mediated by an epimerization reaction of galactose 1-phosphate. free text=Biochemiscal Pathways - An Atlas of Biochemistry and Molecular Biology Edited by Gerhard Michal free text=Biochemistry by Voet and Voet free text=Color Atlas of Biochemistry by Jan Koolman and Klaus-Heinrich Rohm

PARTICIPANT STOICHIOMETRY r6 159
type: Stoichiometry
physical entity: Glucose 6-phosphate
stoichiometric coefficient: 1.0

Fructose-bisphosphate aldolase
type: ProteinReference
xref: PTHR11627:SF42
xref: uniprot Q7KQL9 55
organism: Plasmodium falciparum

ncbitaxon 83333 71
type: UnificationXref
id: 83333
db: ncbitaxon

uniprot Q14376 99
type: UnificationXref
id: Q14376
db: uniprot

uniprot P52789 113
type: UnificationXref
id: P52789
db: uniprot

STATE_TRANSITION_LEFT__Galactose_1_phosphate-RIGHT__Glucose_1_phosphate-_r51
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r51 129
participant stoichiometry: PARTICIPANT STOICHIOMETRY r51 130
left: Galactose 1-phosphate
interaction type: STATE_TRANSITION
right: Glucose 1-phosphate

Pan troglodytes
type: BioSource
xref: ncbitaxon 9598 3

STATE_TRANSITION_LEFT__Glucose-RIGHT__Glucose_6_phosphate-_r5
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 121
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 122
left: Glucose
interaction type: STATE_TRANSITION
right: Glucose 6-phosphate

STATE_TRANSITION_LEFT__NADH__PLUS__H_PLUS_-_Glyceraldehyde-RIGHT__NAD_PLUS_-_Glycerol-_r46
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r46 142
participant stoichiometry: PARTICIPANT STOICHIOMETRY r46 144
participant stoichiometry: PARTICIPANT STOICHIOMETRY r46 143
participant stoichiometry: PARTICIPANT STOICHIOMETRY r46 145
left: NADH + H+
left: Glyceraldehyde
interaction type: STATE_TRANSITION
right: NAD+
right: Glycerol

ncbitaxon 237561 75
type: UnificationXref
id: 237561
db: ncbitaxon

Fructose-bisphosphate aldolase B
type: ProteinReference
xref: uniprot P05062 34
xref: PTHR11627:SF2
organism: Homo sapiens

Xenopus tropicalis
type: BioSource
xref: ncbitaxon 8364 27

PTHR43085:SF1
type: RelationshipXref
id: PTHR43085:SF1
db: PANTHER Family
relationship type: By Homology

Fructose-bisphosphate aldolase C
type: ProteinReference
xref: PTHR11627:SF3
xref: uniprot P05063 35
organism: Mus musculus

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__NADH__PLUS__H_PLUS_-_Glyceraldehyde-RIGHT__NAD_PLUS_-_Glycerol-_r46
controller: Aldehyde reductase

Fructose-bisphosphate aldolase A
type: ProteinReference
xref: PTHR11627:SF1
xref: uniprot P05064 36
organism: Mus musculus

PARTICIPANT STOICHIOMETRY r41 153
type: Stoichiometry
physical entity: Sorbitol
stoichiometric coefficient: 1.0

TRUNCATION_LEFT__Fructose_1_Phosphate-RIGHT__Dihydroxyacetone_3_P-_Glyceraldehyde-_r48
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: TRUNCATION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r48 140
participant stoichiometry: PARTICIPANT STOICHIOMETRY r48 141
participant stoichiometry: PARTICIPANT STOICHIOMETRY r48 139
left: Fructose 1-Phosphate
interaction type: TRUNCATION
right: Dihydroxyacetone 3-P
right: Glyceraldehyde

Hexokinase-2
type: ProteinReference
xref: uniprot P52789 113
organism: Homo sapiens

Fructose-bisphosphate aldolase A
type: ProteinReference
xref: PTHR11627:SF1
xref: uniprot P05065 37
organism: Rattus norvegicus

uniprot Q8JH70 57
type: UnificationXref
id: Q8JH70
db: uniprot

PARTICIPANT STOICHIOMETRY r41 154
type: Stoichiometry
physical entity: Fructose
stoichiometric coefficient: 1.0

Fructose-bisphosphate aldolase B
type: ProteinReference
xref: PTHR11627:SF2
xref: uniprot P00884 30
organism: Rattus norvegicus

UDP-glucose 4-epimerase
type: ProteinReference
xref: uniprot P18645 98
organism: Rattus norvegicus

Glycerol
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PTHR10457:SF6
type: RelationshipXref
id: PTHR10457:SF6
db: PANTHER Family
relationship type: By Homology

ncbitaxon 5759 117
type: UnificationXref
id: 5759
db: ncbitaxon

Ketohexokinase
type: Protein
entity reference: Ketohexokinase
comment: SPECIES_TYPE=PROTEIN

PTHR11627:SF64
type: RelationshipXref
id: PTHR11627:SF64
db: PANTHER Family
relationship type: By Homology

uniprot F6PFR5 15
type: UnificationXref
id: F6PFR5
db: uniprot

uniprot P27881 112
type: UnificationXref
id: P27881
db: uniprot

Fructose-bisphosphate aldolase A
type: ProteinReference
xref: PTHR11627:SF1
xref: uniprot P04075 32
organism: Homo sapiens

PTHR11627:SF68
type: RelationshipXref
id: PTHR11627:SF68
db: PANTHER Family
relationship type: By Homology

uniprot E2RDA6 67
type: UnificationXref
id: E2RDA6
db: uniprot

uniprot P50053 82
type: UnificationXref
id: P50053
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot M0R3X7 108
organism: Rattus norvegicus

ADP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q01415 73
type: UnificationXref
id: Q01415
db: uniprot

Hexose 1-P uridyltransferase
type: Protein
entity reference: Hexose 1-P uridyltransferase
comment: SPECIES_TYPE=PROTEIN

PTHR11943:SF1
type: RelationshipXref
id: PTHR11943:SF1
db: PANTHER Family
relationship type: By Homology

Galactose
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Uncharacterized protein
type: ProteinReference
xref: PTHR11627:SF1
xref: uniprot F1PNI3 13
organism: Canis lupus familiaris

Homo sapiens
type: BioSource
xref: ncbitaxon 9606 33

uniprot P19367 111
type: UnificationXref
id: P19367
db: uniprot

Galactokinase
type: ProteinReference
xref: P02960
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Galactokinase Synonym: Synonym not specified Accession: P02960
comment: ENTITY_REFERENCE_ID_DESC=Fructose galactose metabolism.PROTEIN.GENERIC.Galactokinase
member entity reference: Galactokinase 1
member entity reference: Galactokinase
member entity reference: N-acetylgalactosamine kinase
member entity reference: Uncharacterized protein
member entity reference: GALK2 isoform 7
member entity reference: Galactokinase 2

uniprot F6XUY6 24
type: UnificationXref
id: F6XUY6
db: uniprot

CATALYSIS
type: Catalysis
controlled: TRUNCATION_LEFT__Fructose_1_Phosphate-RIGHT__Dihydroxyacetone_3_P-_Glyceraldehyde-_r48
controller: Fructose bisphosphate aldolase

Fructose-bisphosphate aldolase
type: ProteinReference
xref: PTHR11627:SF2
xref: uniprot F6XUY6 24
organism: Canis lupus familiaris

Putative hexokinase HKDC1
type: ProteinReference
xref: uniprot Q2TB90 118
organism: Homo sapiens

Arabidopsis thaliana
type: BioSource
xref: ncbitaxon 3702 46

Galactose-1-phosphate uridylyltransferase
type: ProteinReference
xref: uniprot P08431 89
xref: PTHR11943:SF1
organism: Saccharomyces cerevisiae

ncbitaxon 10116 31
type: UnificationXref
id: 10116
db: ncbitaxon

uniprot F7A7E8 68
type: UnificationXref
id: F7A7E8
db: uniprot

UDP-galactose 4-epimerase
type: ProteinReference
xref: uniprot Q386N7 100
organism: Trypanosoma brucei

uniprot P05065 37
type: UnificationXref
id: P05065
db: uniprot

uniprot P43424 93
type: UnificationXref
id: P43424
db: uniprot

STATE_TRANSITION_LEFT__UDP_Glucose-RIGHT__UDP_Galactose-_r54
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r54 123
participant stoichiometry: PARTICIPANT STOICHIOMETRY r54 124
left: UDP Glucose
interaction type: STATE_TRANSITION
right: UDP Galactose

PARTICIPANT STOICHIOMETRY r46 144
type: Stoichiometry
physical entity: NAD+
stoichiometric coefficient: 1.0

uniprot Q91Y97 59
type: UnificationXref
id: Q91Y97
db: uniprot

PARTICIPANT STOICHIOMETRY r46 145
type: Stoichiometry
physical entity: Glycerol
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r46 142
type: Stoichiometry
physical entity: NADH + H+
stoichiometric coefficient: 1.0

uniprot E2RB65 85
type: UnificationXref
id: E2RB65
db: uniprot

PARTICIPANT STOICHIOMETRY r46 143
type: Stoichiometry
physical entity: Glyceraldehyde
stoichiometric coefficient: 1.0

ncbitaxon 9606 33
type: UnificationXref
id: 9606
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r49 131
type: Stoichiometry
physical entity: ATP
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r52 128
type: Stoichiometry
physical entity: Glucose 6-phosphate
stoichiometric coefficient: 1.0

Fructose-bisphosphate aldolase 2, chloroplastic
type: ProteinReference
xref: PTHR11627:SF64
xref: uniprot Q944G9 60
organism: Arabidopsis thaliana

PARTICIPANT STOICHIOMETRY r52 127
type: Stoichiometry
physical entity: Glucose 1-phosphate
stoichiometric coefficient: 1.0

UDP Glucose 4 epimerase
type: Protein
entity reference: UDP Glucose 4 epimerase
comment: SPECIES_TYPE=PROTEIN

uniprot P04075 32
type: UnificationXref
id: P04075
db: uniprot

PARTICIPANT STOICHIOMETRY r49 134
type: Stoichiometry
physical entity: Glyceraldehyde 3-P
stoichiometric coefficient: 1.0

Galactokinase
type: ProteinReference
xref: uniprot Q59VY8 74
organism: Candida albicans

uniprot Q9R0N0 79
type: UnificationXref
id: Q9R0N0
db: uniprot

PARTICIPANT STOICHIOMETRY r49 133
type: Stoichiometry
physical entity: ADP
stoichiometric coefficient: 1.0

ncbitaxon 39947 50
type: UnificationXref
id: 39947
db: ncbitaxon

Danio rerio
type: BioSource
xref: ncbitaxon 7955 58

Escherichia coli
type: BioSource
xref: ncbitaxon 83333 71

PARTICIPANT STOICHIOMETRY r49 132
type: Stoichiometry
physical entity: Glyceraldehyde
stoichiometric coefficient: 1.0

TRUNCATION
type: RelationshipTypeVocabulary

uniprot P0CN76 91
type: UnificationXref
id: P0CN76
db: uniprot

Galactose-1-phosphate uridylyltransferase
type: ProteinReference
xref: PTHR11943:SF1
xref: uniprot P43424 93
organism: Rattus norvegicus

Bifunctional protein GAL10
type: ProteinReference
xref: uniprot P04397 96
organism: Saccharomyces cerevisiae

UDP-glucose 4-epimerase
type: ProteinReference
xref: uniprot Q14376 99
organism: Homo sapiens

NADH + H+
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Fructose-bisphosphate aldolase
type: ProteinReference
xref: PTHR11627:SF3
xref: uniprot F6PFR5 15
organism: Ornithorhynchus anatinus

uniprot Q8R059 102
type: UnificationXref
id: Q8R059
db: uniprot

Fructose-bisphosphate aldolase
type: ProteinReference
xref: uniprot A6ZI46 10
xref: PTHR11627:SF1
organism: Mus musculus

Hexokinase
type: Protein
entity reference: Hexokinase
comment: SPECIES_TYPE=PROTEIN

STATE_TRANSITION_LEFT__UDP_Galactose-RIGHT__UDP_Glucose-_r53
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r53 126
participant stoichiometry: PARTICIPANT STOICHIOMETRY r53 125
left: UDP Galactose
interaction type: STATE_TRANSITION
right: UDP Glucose

Fructose-bisphosphate aldolase 8, cytosolic
type: ProteinReference
xref: PTHR11627:SF44
xref: uniprot Q9LF98 61
organism: Arabidopsis thaliana

Fructose-bisphosphate aldolase 6, cytosolic
type: ProteinReference
xref: PTHR11627:SF42
xref: uniprot Q9SJQ9 62
organism: Arabidopsis thaliana

uniprot P09117 43
type: UnificationXref
id: P09117
db: uniprot

STATE_TRANSITION_LEFT__Sorbitol-RIGHT__Fructose-_r41
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r41 154
participant stoichiometry: PARTICIPANT STOICHIOMETRY r41 153
left: Sorbitol
interaction type: STATE_TRANSITION
right: Fructose

ncbitaxon 5664 52
type: UnificationXref
id: 5664
db: ncbitaxon

Fructose 1,6-phosphate
type: SmallMolecule
cellular location: Glycolysis c2
comment: SPECIES_TYPE=SIMPLE_MOLECULE

eco ECO:0000250 4
type: UnificationXref
id: ECO:0000250
db: eco

ncbitaxon 10090 11
type: UnificationXref
id: 10090
db: ncbitaxon

Fructose-bisphosphate aldolase
type: ProteinReference
xref: PTHR11627:SF3
xref: uniprot F6WHL1 23
organism: Macaca mulatta

Fructose-bisphosphate aldolase C-B
type: ProteinReference
xref: PTHR11627:SF3
xref: uniprot Q8JH70 57
organism: Danio rerio

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__UDP_Galactose-RIGHT__UDP_Glucose-_r53
controller: Hexose 1-P uridyltransferase

uniprot Q9SJQ9 62
type: UnificationXref
id: Q9SJQ9
db: uniprot

STATE_TRANSITION_LEFT__ATP-_Glyceraldehyde-RIGHT__ADP-_Glyceraldehyde_3_P-_r49
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r49 132
participant stoichiometry: PARTICIPANT STOICHIOMETRY r49 131
participant stoichiometry: PARTICIPANT STOICHIOMETRY r49 134
participant stoichiometry: PARTICIPANT STOICHIOMETRY r49 133
left: ATP
left: Glyceraldehyde
interaction type: STATE_TRANSITION
right: Glyceraldehyde 3-P
right: ADP

Glucose 6-phosphate
type: SmallMolecule
cellular location: Glycolysis c2
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r48 141
type: Stoichiometry
physical entity: Glyceraldehyde
stoichiometric coefficient: 1.0

uniprot Q9W330 120
type: UnificationXref
id: Q9W330
db: uniprot

PARTICIPANT STOICHIOMETRY r48 140
type: Stoichiometry
physical entity: Dihydroxyacetone 3-P
stoichiometric coefficient: 1.0

uniprot Q06204 114
type: UnificationXref
id: Q06204
db: uniprot

PARTICIPANT STOICHIOMETRY r44 147
type: Stoichiometry
physical entity: Fructose
stoichiometric coefficient: 1.0

Fructose bisphosphate aldolase
type: ProteinReference
xref: P02959
comment: ENTITY_REFERENCE_ID_DESC=Fructose galactose metabolism.PROTEIN.GENERIC.Fructose bisphosphate_br_aldolase
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Fructose bisphosphate aldolase Synonym: Synonym not specified Accession: P02959
member entity reference: Fructose-bisphosphate aldolase B
member entity reference: Fructose-bisphosphate aldolase
member entity reference: Fructose-bisphosphate aldolase A
member entity reference: Fructose-bisphosphate aldolase C-B
member entity reference: Uncharacterized protein
member entity reference: Fructose-bisphosphate aldolase C
member entity reference: Fructose-bisphosphate aldolase 7, cytosolic
member entity reference: Fructose-bisphosphate aldolase 6, cytosolic
member entity reference: Fructose-bisphosphate aldolase 2, chloroplastic
member entity reference: Fructose-bisphosphate aldolase 8, cytosolic
member entity reference: Fructose-bisphosphate aldolase, chloroplastic
member entity reference: Fructose-bisphosphate aldolase 1, chloroplastic

PARTICIPANT STOICHIOMETRY r44 146
type: Stoichiometry
physical entity: ATP
stoichiometric coefficient: 1.0

uniprot A0A3S5ZPB0 8
type: UnificationXref
id: A0A3S5ZPB0
db: uniprot

Hexokinase domain containing 1
type: ProteinReference
xref: uniprot H2Q205 106
organism: Pan troglodytes

Ketohexokinase
type: ProteinReference
xref: uniprot P97328 83
xref: PTHR43085:SF1
organism: Mus musculus

Glycolysis c2
type: CellularLocationVocabulary
comment: Glycolysis

PARTICIPANT STOICHIOMETRY r44 149
type: Stoichiometry
physical entity: Fructose 1-Phosphate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r44 148
type: Stoichiometry
physical entity: ADP
stoichiometric coefficient: 1.0

Bos taurus
type: BioSource
xref: ncbitaxon 9913 7

ncbitaxon 3702 46
type: UnificationXref
id: 3702
db: ncbitaxon

Macaca mulatta
type: BioSource
xref: ncbitaxon 9544 21

Galactokinase 1
type: ProteinReference
xref: PTHR10457:SF6
xref: uniprot Q5RKH2 76
organism: Rattus norvegicus

PARTICIPANT STOICHIOMETRY r5 121
type: Stoichiometry
physical entity: Glucose
stoichiometric coefficient: 1.0

uniprot P09147 97
type: UnificationXref
id: P09147
db: uniprot

uniprot F7E0Q7 25
type: UnificationXref
id: F7E0Q7
db: uniprot

PARTICIPANT STOICHIOMETRY r5 122
type: Stoichiometry
physical entity: Glucose 6-phosphate
stoichiometric coefficient: 1.0

ATP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Fructose-bisphosphate aldolase
type: ProteinReference
xref: PTHR11627:SF2
xref: uniprot F6QY90 19
organism: Ornithorhynchus anatinus

Ornithorhynchus anatinus
type: BioSource
xref: ncbitaxon 9258 16

ncbitaxon 214684 92
type: UnificationXref
id: 214684
db: ncbitaxon

uniprot A6ZI47 12
type: UnificationXref
id: A6ZI47
db: uniprot

IEA
type: EvidenceCodeVocabulary
xref: eco ECO:0000501 115

uniprot Q4Q1V0 51
type: UnificationXref
id: Q4Q1V0
db: uniprot

uniprot Q2TB90 118
type: UnificationXref
id: Q2TB90
db: uniprot

NAD+
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Trypanosoma brucei
type: BioSource
xref: ncbitaxon 185431 101

NAS
type: EvidenceCodeVocabulary
xref: eco ECO:0000303 42

Fructose 6-phosphate
type: SmallMolecule
cellular location: Glycolysis c2
comment: SPECIES_TYPE=SIMPLE_MOLECULE

TAS
type: EvidenceCodeVocabulary
xref: eco ECO:0000304 47

Dihydroxyacetone 3-P
type: SmallMolecule
cellular location: Glycolysis c2
comment: SPECIES_TYPE=SIMPLE_MOLECULE

STATE_TRANSITION_LEFT__Fructose_6_phosphate-RIGHT__Fructose_1,6_phosphate-_r38
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r38 156
participant stoichiometry: PARTICIPANT STOICHIOMETRY r38 155
left: Fructose 6-phosphate
interaction type: STATE_TRANSITION
right: Fructose 1,6-phosphate

Fructose-bisphosphate aldolase
type: ProteinReference
xref: uniprot A6ZI47 12
xref: PTHR11627:SF1
organism: Mus musculus

uniprot M0R3X7 108
type: UnificationXref
id: M0R3X7
db: uniprot

Putative hexokinase HKDC1
type: ProteinReference
xref: uniprot Q91W97 119
organism: Mus musculus

UDP Glucose
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Fructose-bisphosphate aldolase C
type: ProteinReference
xref: PTHR11627:SF3
xref: uniprot P09117 43
organism: Rattus norvegicus

eco ECO:0000303 42
type: UnificationXref
id: ECO:0000303
db: eco

PTHR11627:SF3
type: RelationshipXref
id: PTHR11627:SF3
db: PANTHER Family
relationship type: By Homology

PTHR11627:SF2
type: RelationshipXref
id: PTHR11627:SF2
db: PANTHER Family
relationship type: By Homology

Fructose-bisphosphate aldolase
type: ProteinReference
xref: uniprot F6SYK8 22
xref: PTHR11627:SF2
organism: Macaca mulatta

uniprot Q40677 49
type: UnificationXref
id: Q40677
db: uniprot

uniprot P17710 110
type: UnificationXref
id: P17710
db: uniprot

uniprot Q03249 94
type: UnificationXref
id: Q03249
db: uniprot

uniprot P05064 36
type: UnificationXref
id: P05064
db: uniprot

PTHR11627:SF1
type: RelationshipXref
id: PTHR11627:SF1
db: PANTHER Family
relationship type: By Homology

PTHR19443:SF16
type: RelationshipXref
id: PTHR19443:SF16
db: PANTHER Family
relationship type: By Homology

uniprot F6Y855 104
type: UnificationXref
id: F6Y855
db: uniprot

uniprot A0A2I3SY22 64
type: UnificationXref
id: A0A2I3SY22
db: uniprot

uniprot F7GPR3 80
type: UnificationXref
id: F7GPR3
db: uniprot

uniprot H2QCI1 28
type: UnificationXref
id: H2QCI1
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A3Q1M891 65
organism: Bos taurus

Fructose-bisphosphate aldolase B
type: ProteinReference
xref: uniprot P07341 38
xref: PTHR11627:SF2
organism: Gallus gallus

Aldehyde reductase
type: Protein
comment: SPECIES_TYPE=PROTEIN

Galactose 1-phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot F6Q724 103
type: UnificationXref
id: F6Q724
db: uniprot

GALK2 isoform 7
type: ProteinReference
xref: uniprot A0A2I3SY22 64
organism: Pan troglodytes

uniprot P18645 98
type: UnificationXref
id: P18645
db: uniprot

Fructose-bisphosphate aldolase 7, cytosolic
type: ProteinReference
xref: uniprot P22197 45
xref: PTHR11627:SF20
organism: Arabidopsis thaliana

Rattus norvegicus
type: BioSource
xref: ncbitaxon 10116 31

Triokinase
type: Protein
comment: SPECIES_TYPE=PROTEIN

Galactokinase
type: ProteinReference
xref: PTHR10457:SF6
xref: uniprot P0A6T3 70
organism: Escherichia coli

Fructose-bisphosphate aldolase
type: ProteinReference
xref: PTHR11627:SF42
xref: uniprot P07764 40
organism: Drosophila melanogaster

Canis lupus familiaris
type: BioSource
xref: ncbitaxon 9615 14

uniprot P97328 83
type: UnificationXref
id: P97328
db: uniprot

uniprot A0A3Q1LMG1 6
type: UnificationXref
id: A0A3Q1LMG1
db: uniprot

Galactokinase 2
type: ProteinReference
xref: uniprot E2RDA6 67
organism: Canis lupus familiaris

uniprot F6QY90 19
type: UnificationXref
id: F6QY90
db: uniprot

PARTICIPANT STOICHIOMETRY r6 160
type: Stoichiometry
physical entity: Fructose 6-phosphate
stoichiometric coefficient: 1.0

uniprot F7HAC6 105
type: UnificationXref
id: F7HAC6
db: uniprot

Fructose-bisphosphate aldolase
type: ProteinReference
xref: PTHR11627:SF1
xref: uniprot F7E0Q7 25
organism: Monodelphis domestica

uniprot Q9GKK4 78
type: UnificationXref
id: Q9GKK4
db: uniprot

PARTICIPANT STOICHIOMETRY r54 124
type: Stoichiometry
physical entity: UDP Galactose
stoichiometric coefficient: 1.0

uniprot P08431 89
type: UnificationXref
id: P08431
db: uniprot

Fructose-bisphosphate aldolase
type: ProteinReference
xref: PTHR11627:SF1
xref: uniprot F6SYJ3 20
organism: Macaca mulatta

PARTICIPANT STOICHIOMETRY r54 123
type: Stoichiometry
physical entity: UDP Glucose
stoichiometric coefficient: 1.0

uniprot P22197 45
type: UnificationXref
id: P22197
db: uniprot

Fructose-bisphosphate aldolase
type: ProteinReference
xref: PTHR11627:SF1
xref: uniprot F7E7R1 26
organism: Xenopus tropicalis

Galactokinase
type: Protein
entity reference: Galactokinase
comment: SPECIES_TYPE=PROTEIN

Fructose-bisphosphate aldolase
type: ProteinReference
xref: PTHR11627:SF42
xref: uniprot Q4Q1V0 51
organism: Leishmania major

Fructose-bisphosphate aldolase 1, chloroplastic
type: ProteinReference
xref: PTHR11627:SF68
xref: uniprot Q9SJU4 63
organism: Arabidopsis thaliana

P02966
type: UnificationXref
id: P02966
db: PANTHER Pathway Component

P02965
type: UnificationXref
id: P02965
db: PANTHER Pathway Component

PARTICIPANT STOICHIOMETRY r51 130
type: Stoichiometry
physical entity: Glucose 1-phosphate
stoichiometric coefficient: 1.0

P02964
type: UnificationXref
id: P02964
db: PANTHER Pathway Component

uniprot Q91W97 119
type: UnificationXref
id: Q91W97
db: uniprot

P02963
type: UnificationXref
id: P02963
db: PANTHER Pathway Component

Gallus gallus
type: BioSource
xref: ncbitaxon 9031 39

uniprot H2Q205 106
type: UnificationXref
id: H2Q205
db: uniprot

uniprot A0A2I3SKK2 2
type: UnificationXref
id: A0A2I3SKK2
db: uniprot

uniprot Q9SJU4 63
type: UnificationXref
id: Q9SJU4
db: uniprot

KNOWN_TRANSITION_OMITTED
type: RelationshipTypeVocabulary

uniprot H2QI73 107
type: UnificationXref
id: H2QI73
db: uniprot

STATE_TRANSITION_LEFT__Galactose-_ATP-RIGHT__ADP-_Galactose_1_phosphate-_r50
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r50 136
participant stoichiometry: PARTICIPANT STOICHIOMETRY r50 135
participant stoichiometry: PARTICIPANT STOICHIOMETRY r50 137
participant stoichiometry: PARTICIPANT STOICHIOMETRY r50 138
left: ATP
left: Galactose
interaction type: STATE_TRANSITION
right: Galactose 1-phosphate
right: ADP

uniprot A5A6I5 9
type: UnificationXref
id: A5A6I5
db: uniprot

P02960
type: UnificationXref
id: P02960
db: PANTHER Pathway Component

Ketohexokinase
type: ProteinReference
xref: P02963
comment: ENTITY_REFERENCE_ID_DESC=Fructose galactose metabolism.PROTEIN.GENERIC.Ketohexokinase
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Ketohexokinase Synonym: Synonym not specified Accession: P02963
member entity reference: Ketohexokinase
member entity reference: KHK isoform 2
member entity reference: Uncharacterized protein

Glyceraldehyde 3-P
type: SmallMolecule
cellular location: Glycolysis c2
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot A6H768 66
type: UnificationXref
id: A6H768
db: uniprot

Galactokinase
type: ProteinReference
xref: PTHR10457:SF6
xref: uniprot P51570 72
organism: Homo sapiens

Fructose
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ncbitaxon 9544 21
type: UnificationXref
id: 9544
db: ncbitaxon

P02959
type: UnificationXref
id: P02959
db: PANTHER Pathway Component

Hexokinase-2
type: ProteinReference
xref: uniprot O08528 109
organism: Mus musculus

uniprot Q6AY07 53
type: UnificationXref
id: Q6AY07
db: uniprot

uniprot Q27648 116
type: UnificationXref
id: Q27648
db: uniprot

STATE_TRANSITION
type: RelationshipTypeVocabulary

STATE_TRANSITION
type: InteractionVocabulary

PANTHER Pathway P02744 1
type: UnificationXref
id: P02744
db: PANTHER Pathway

ncbitaxon 7955 58
type: UnificationXref
id: 7955
db: ncbitaxon

uniprot Q944G9 60
type: UnificationXref
id: Q944G9
db: uniprot

PARTICIPANT STOICHIOMETRY r51 129
type: Stoichiometry
physical entity: Galactose 1-phosphate
stoichiometric coefficient: 1.0

KNOWN_TRANSITION_OMITTED_LEFT__Glyceraldehyde_3_P-RIGHT__Pyruvate-_r40
type: Conversion
conversion direction: LEFT_TO_RIGHT
xref: KNOWN TRANSITION OMITTED
participant stoichiometry: PARTICIPANT STOICHIOMETRY r40 158
participant stoichiometry: PARTICIPANT STOICHIOMETRY r40 157
left: Glyceraldehyde 3-P
interaction type: KNOWN_TRANSITION_OMITTED
right: Pyruvate

Fructose bisphosphate aldolase
type: Protein
entity reference: Fructose bisphosphate aldolase
comment: SPECIES_TYPE=PROTEIN

TRUNCATION
type: InteractionVocabulary

PARTICIPANT STOICHIOMETRY r50 137
type: Stoichiometry
physical entity: ADP
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r50 136
type: Stoichiometry
physical entity: ATP
stoichiometric coefficient: 1.0

Uncharacterized protein
type: ProteinReference
xref: uniprot F6Q724 103
organism: Macaca mulatta

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__ATP-_Fructose-RIGHT__ADP-_Fructose_1_Phosphate-_r44
controller: Ketohexokinase

PARTICIPANT STOICHIOMETRY r50 135
type: Stoichiometry
physical entity: Galactose
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r50 138
type: Stoichiometry
physical entity: Galactose 1-phosphate
stoichiometric coefficient: 1.0

uniprot Q9LF98 61
type: UnificationXref
id: Q9LF98
db: uniprot

KHK isoform 2
type: ProteinReference
xref: PTHR43085:SF1
xref: uniprot H2QHL3 81
organism: Pan troglodytes

Candida albicans
type: BioSource
xref: ncbitaxon 237561 75

Phosphotransferase
type: ProteinReference
xref: uniprot Q9W330 120
organism: Drosophila melanogaster

eco ECO:0000270 29
type: UnificationXref
id: ECO:0000270
db: eco

KNOWN_TRANSITION_OMITTED
type: InteractionVocabulary

ncbitaxon 9615 14
type: UnificationXref
id: 9615
db: ncbitaxon

Fructose 1-Phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Fructose-bisphosphate aldolase
type: ProteinReference
xref: uniprot F6Q8Q1 17
xref: PTHR11627:SF3
organism: Monodelphis domestica

IDA
type: EvidenceCodeVocabulary

uniprot Q6NVQ9 54
type: UnificationXref
id: Q6NVQ9
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__ATP-_Glyceraldehyde-RIGHT__ADP-_Glyceraldehyde_3_P-_r49
controller: Triokinase

Leishmania major
type: BioSource
xref: ncbitaxon 5664 52

uniprot F6SYJ3 20
type: UnificationXref
id: F6SYJ3
db: uniprot

uniprot Q3T0S5 48
type: UnificationXref
id: Q3T0S5
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F7A7E8 68
organism: Macaca mulatta

uniprot Q58CX1 95
type: UnificationXref
id: Q58CX1
db: uniprot

Fructose-bisphosphate aldolase B
type: ProteinReference
xref: uniprot Q3T0S5 48
xref: PTHR11627:SF2
organism: Bos taurus

Fructose-bisphosphate aldolase
type: ProteinReference
xref: PTHR11627:SF3
xref: uniprot Q6NVQ9 54
organism: Xenopus tropicalis

STATE_TRANSITION_LEFT__ATP-_Fructose-RIGHT__ADP-_Fructose_1_Phosphate-_r44
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r44 149
participant stoichiometry: PARTICIPANT STOICHIOMETRY r44 146
participant stoichiometry: PARTICIPANT STOICHIOMETRY r44 148
participant stoichiometry: PARTICIPANT STOICHIOMETRY r44 147
left: ATP
left: Fructose
interaction type: STATE_TRANSITION
right: ADP
right: Fructose 1-Phosphate

uniprot P0A6T3 70
type: UnificationXref
id: P0A6T3
db: uniprot

STATE_TRANSITION_LEFT__Glucose_6_phosphate-RIGHT__Fructose_6_phosphate-_r6
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 159
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 160
left: Glucose 6-phosphate
interaction type: STATE_TRANSITION
right: Fructose 6-phosphate

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Sorbitol-RIGHT__Fructose-_r41
controller: Hexokinase

Uncharacterized protein
type: ProteinReference
xref: uniprot F7HAC6 105
organism: Macaca mulatta

Fructose-bisphosphate aldolase A
type: ProteinReference
xref: PTHR11627:SF1
xref: uniprot A5A6I5 9
organism: Pan troglodytes

Uncharacterized protein
type: ProteinReference
xref: uniprot F6Y855 104
organism: Macaca mulatta

ncbitaxon 185431 101
type: UnificationXref
id: 185431
db: ncbitaxon

ncbitaxon 559292 90
type: UnificationXref
id: 559292
db: ncbitaxon

ncbitaxon 9598 3
type: UnificationXref
id: 9598
db: ncbitaxon

ncbitaxon 36329 56
type: UnificationXref
id: 36329
db: ncbitaxon

Hexose 1-P uridyltransferase
type: ProteinReference
xref: P02964
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Hexose 1-P uridyltransferase Synonym: Synonym not specified Accession: P02964
comment: ENTITY_REFERENCE_ID_DESC=Fructose galactose metabolism.PROTEIN.GENERIC.Hexose 1-P_br_uridyltransferase
member entity reference: Galactose-1-phosphate uridylyltransferase

Hexokinase-1
type: ProteinReference
xref: uniprot P19367 111
organism: Homo sapiens

uniprot P07764 40
type: UnificationXref
id: P07764
db: uniprot

Galactose-1-phosphate uridylyltransferase
type: ProteinReference
xref: uniprot Q03249 94
xref: PTHR11943:SF1
organism: Mus musculus

Fructose-bisphosphate aldolase C
type: ProteinReference
xref: PTHR11627:SF3
xref: uniprot P09972 44
organism: Homo sapiens

PARTICIPANT STOICHIOMETRY r48 139
type: Stoichiometry
physical entity: Fructose 1-Phosphate
stoichiometric coefficient: 1.0

uniprot F6SYK8 22
type: UnificationXref
id: F6SYK8
db: uniprot

PARTICIPANT STOICHIOMETRY r38 156
type: Stoichiometry
physical entity: Fructose 1,6-phosphate
stoichiometric coefficient: 1.0

UDP-glucose 4-epimerase
type: ProteinReference
xref: uniprot P09147 97
organism: Escherichia coli

Hexokinase
type: ProteinReference
xref: P02966
comment: ENTITY_REFERENCE_NOTES=Long Name: Hexokinase Synonym: Synonym not specified Accession: P02966
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Fructose galactose metabolism.PROTEIN.GENERIC.Hexokinase
member entity reference: Putative hexokinase HKDC1
member entity reference: Hexokinase-1
member entity reference: Hexokinase-2
member entity reference: Uncharacterized protein
member entity reference: Hexokinase 2
member entity reference: Phosphotransferase
member entity reference: Putative hexokinase YLR446W
member entity reference: Hexokinase domain containing 1

PARTICIPANT STOICHIOMETRY r38 155
type: Stoichiometry
physical entity: Fructose 6-phosphate
stoichiometric coefficient: 1.0

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__UDP_Glucose-RIGHT__UDP_Galactose-_r54
controller: UDP Glucose 4 epimerase

ncbitaxon 9258 16
type: UnificationXref
id: 9258
db: ncbitaxon

Fructose-bisphosphate aldolase
type: ProteinReference
xref: PTHR11627:SF1
xref: uniprot Q6AY07 53
organism: Rattus norvegicus

Ketohexokinase
type: ProteinReference
xref: PTHR43085:SF1
xref: uniprot P50053 82
organism: Homo sapiens

uniprot O33836 86
type: UnificationXref
id: O33836
db: uniprot

STATE_TRANSITION_LEFT__Glucose_1_phosphate-RIGHT__Glucose_6_phosphate-_r52
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r52 128
participant stoichiometry: PARTICIPANT STOICHIOMETRY r52 127
left: Glucose 1-phosphate
interaction type: STATE_TRANSITION
right: Glucose 6-phosphate

Oryza sativa
type: BioSource
xref: ncbitaxon 39947 50

PARTICIPANT STOICHIOMETRY r39 150
type: Stoichiometry
physical entity: Fructose 1,6-phosphate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r39 151
type: Stoichiometry
physical entity: Dihydroxyacetone 3-P
stoichiometric coefficient: 1.0

uniprot A6ZI46 10
type: UnificationXref
id: A6ZI46
db: uniprot

PARTICIPANT STOICHIOMETRY r39 152
type: Stoichiometry
physical entity: Glyceraldehyde 3-P
stoichiometric coefficient: 1.0

Galactose-1-phosphate uridylyltransferase
type: ProteinReference
xref: uniprot Q58CX1 95
xref: PTHR11943:SF1
organism: Bos taurus

uniprot F6Q8Q1 17
type: UnificationXref
id: F6Q8Q1
db: uniprot

Glucose 1-phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE