Glyceraldehyde-3-phosphate dehydrogenase A
type: ProteinReference
xref: uniprot P0A9B2 91
organism: Escherichia coli

Triosephosphate isomerase
type: ProteinReference
xref: P00673
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Triosephosphate isomerase Synonym: Synonym not specified Accession: P00673
comment: ENTITY_REFERENCE_ID_DESC=Glycolysis.PROTEIN.GENERIC.Triosephosphate_br_isomerase
member entity reference: Triosephosphate isomerase
member entity reference: Phosphoglycerate kinase 3, cytosolic

ncbitaxon 284591 21
type: UnificationXref
id: 284591
db: ncbitaxon

ATP-dependent 6-phosphofructokinase
type: ProteinReference
xref: uniprot A0A1D5QYR2 37
organism: Macaca mulatta

uniprot A6ZI47 137
type: UnificationXref
id: A6ZI47
db: uniprot

2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
type: ProteinReference
xref: PTHR11931:SF0
xref: uniprot P9WIC9 170
organism: Mycobacterium tuberculosis

uniprot O88015 64
type: UnificationXref
id: O88015
db: uniprot

Phosphoglucose isomerase
type: Protein
entity reference: Phosphoglucose isomerase
comment: SPECIES_TYPE=PROTEIN

uniprot P15259 162
type: UnificationXref
id: P15259
db: uniprot

STATE_TRANSITION_LEFT__ATP-_Fructose_6_phosphate-RIGHT__ADP-_Fructose_1,_6_bisphosphate-_r9
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r9 209
participant stoichiometry: PARTICIPANT STOICHIOMETRY r9 208
participant stoichiometry: PARTICIPANT STOICHIOMETRY r9 211
participant stoichiometry: PARTICIPANT STOICHIOMETRY r9 210
left: Fructose 6-phosphate
left: ATP
interaction type: STATE_TRANSITION
right: ADP
right: Fructose 1, 6-bisphosphate

ATP-dependent 6-phosphofructokinase
type: ProteinReference
xref: uniprot K7AUT0 39
organism: Pan troglodytes

By Homology
type: RelationshipTypeVocabulary

PARTICIPANT STOICHIOMETRY r10 207
type: Stoichiometry
physical entity: Dihydroxyacetone phosphate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r10 206
type: Stoichiometry
physical entity: Fructose 1, 6-bisphosphate
stoichiometric coefficient: 1.0

Pyruvate kinase PKLR
type: ProteinReference
xref: uniprot P30613 77
organism: Homo sapiens

2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
type: ProteinReference
xref: PTHR11931:SF0
xref: uniprot Q8RFG9 175
organism: Fusobacterium nucleatum

uniprot Q93Z53 81
type: UnificationXref
id: Q93Z53
db: uniprot

Mus musculus
type: BioSource
xref: ncbitaxon 10090 15

Glycolysis
type: Pathway
pathway component: STATE_TRANSITION_LEFT__1,_3_Bisphosphoglycerate-_2_ADP-RIGHT__2_ATP-_3_Phosphoglycerate-_r16
pathway component: STATE_TRANSITION_LEFT__Glucose_6_phosphate-RIGHT__Fructose_6_phosphate-_r6
pathway component: STATE_TRANSITION_LEFT__Phosphoenolpyruvate-_2_ADP-RIGHT__2_ATP-_Pyruvate-_r19
pathway component: STATE_TRANSITION_LEFT__Glucose-_ATP-RIGHT__Glucose_6_phosphate-_ADP-_r5
pathway component: STATE_TRANSITION_LEFT__Fructose_1,_6_bisphosphate-RIGHT__Dihydroxyacetone_phosphate-_r10
pathway component: STATE_TRANSITION_LEFT__Fructose_1,_6_bisphosphate-RIGHT__Glyceraldehyde_3_phosphate-_r11
pathway component: STATE_TRANSITION_LEFT__Glyceraldehyde_3_phosphate-RIGHT__Dihydroxyacetone_phosphate-_r13
pathway component: STATE_TRANSITION_LEFT__2_NAD_PLUS___PLUS__2_Pi-_Glyceraldehyde_3_phosphate-RIGHT__2_NADH__PLUS__2_H_PLUS_-_1,_3_Bisphosphoglycerate-_r14
pathway component: STATE_TRANSITION_LEFT__ATP-_Fructose_6_phosphate-RIGHT__ADP-_Fructose_1,_6_bisphosphate-_r9
pathway component: STATE_TRANSITION_LEFT__Dihydroxyacetone_phosphate-RIGHT__Glyceraldehyde_3_phosphate-_r12
pathway component: STATE_TRANSITION_LEFT__2_Phosphoglycerate-RIGHT__2_H2O-_Phosphoenolpyruvate-_r18
pathway component: STATE_TRANSITION_LEFT__3_Phosphoglycerate-RIGHT__2_Phosphoglycerate-_r17
xref: PANTHER Pathway P00024 1
comment: MODEL_NOTES=Glycolysis: A well documented metabolic pathway, which involves a series of enzymatic reactions to convert one molecule of glucose to two molecules of pyruvate. free text=Molecular and Cell Biology (4th Edition) by Lodish, Berk, Zipursky, Matsudaria, Baltimore, and Darnell

Saccharomyces cerevisiae
type: BioSource
xref: ncbitaxon 559292 52

Drosophila melanogaster
type: BioSource
xref: ncbitaxon 7227 57

Yarrowia lipolytica
type: BioSource
xref: ncbitaxon 284591 21

PTHR11469:SF1
type: RelationshipXref
id: PTHR11469:SF1
db: PANTHER Family
relationship type: By Homology

Hexokinase-1
type: ProteinReference
xref: PTHR19443:SF10
xref: uniprot P17710 103
organism: Mus musculus

uniprot O84727 158
type: UnificationXref
id: O84727
db: uniprot

PTHR11931:SF0
type: RelationshipXref
id: PTHR11931:SF0
db: PANTHER Family
relationship type: By Homology

Phosphoglycerate kinase
type: ProteinReference
xref: uniprot F6SW40 8
xref: PTHR11406:SF0
organism: Monodelphis domestica

Phosphoglycerate kinase
type: ProteinReference
xref: uniprot P27362 18
xref: PTHR11406:SF0
organism: Plasmodium falciparum

PTHR11931:SF9
type: RelationshipXref
id: PTHR11931:SF9
db: PANTHER Family
relationship type: By Homology

PTHR11627:SF42
type: RelationshipXref
id: PTHR11627:SF42
db: PANTHER Family
relationship type: By Homology

Neurospora crassa
type: BioSource
xref: ncbitaxon 367110 24

Plasmodium falciparum
type: BioSource
xref: ncbitaxon 36329 19

ATP-dependent 6-phosphofructokinase
type: ProteinReference
xref: uniprot K7DD35 41
organism: Pan troglodytes

Glucose-6-phosphate isomerase 1
type: ProteinReference
xref: PTHR11469:SF1
xref: uniprot O88015 64
organism: Streptomyces coelicolor

uniprot F7HAC6 98
type: UnificationXref
id: F7HAC6
db: uniprot

Alpha-enolase
type: ProteinReference
xref: uniprot P17182 127
xref: PTHR11902:SF12
organism: Mus musculus

Gamma-enolase
type: ProteinReference
xref: PTHR11902:SF10
xref: uniprot P17183 128
organism: Mus musculus

ncbitaxon 39947 69
type: UnificationXref
id: 39947
db: ncbitaxon

uniprot P15327 163
type: UnificationXref
id: P15327
db: uniprot

Glyceraldehyde-3-phosphate dehydrogenase 1
type: ProteinReference
xref: uniprot P04970 87
organism: Caenorhabditis elegans

uniprot P27881 105
type: UnificationXref
id: P27881
db: uniprot

Triosephosphate isomerase
type: Protein
entity reference: Triosephosphate isomerase
comment: SPECIES_TYPE=PROTEIN

Phosphoglycerate mutase 1
type: ProteinReference
xref: uniprot P25113 165
organism: Rattus norvegicus

uniprot Q6P6V0 71
type: UnificationXref
id: Q6P6V0
db: uniprot

ncbitaxon 36329 19
type: UnificationXref
id: 36329
db: ncbitaxon

uniprot Q4Q1V0 146
type: UnificationXref
id: Q4Q1V0
db: uniprot

uniprot P00558 12
type: UnificationXref
id: P00558
db: uniprot

2 ATP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot P42863 70
type: UnificationXref
id: P42863
db: uniprot

Pan troglodytes
type: BioSource
xref: ncbitaxon 9598 40

PARTICIPANT STOICHIOMETRY r6 213
type: Stoichiometry
physical entity: Fructose 6-phosphate
stoichiometric coefficient: 1.0

Xenopus tropicalis
type: BioSource
xref: ncbitaxon 8364 114

PARTICIPANT STOICHIOMETRY r6 212
type: Stoichiometry
physical entity: Glucose 6-phosphate
stoichiometric coefficient: 1.0

Glucose-6-phosphate isomerase
type: ProteinReference
xref: uniprot Q6P6V0 71
organism: Rattus norvegicus

ncbitaxon 9598 40
type: UnificationXref
id: 9598
db: ncbitaxon

Phosphoglycerate kinase 1
type: ProteinReference
xref: uniprot P09411 14
xref: PTHR11406:SF14
organism: Mus musculus

ncbitaxon 13616 9
type: UnificationXref
id: 13616
db: ncbitaxon

uniprot P38667 23
type: UnificationXref
id: P38667
db: uniprot

uniprot P04797 86
type: UnificationXref
id: P04797
db: uniprot

Phosphoglycerate kinase
type: ProteinReference
xref: uniprot F7C393 11
xref: PTHR11406:SF0
organism: Monodelphis domestica

ncbitaxon 178306 36
type: UnificationXref
id: 178306
db: ncbitaxon

uniprot P17710 103
type: UnificationXref
id: P17710
db: uniprot

Alpha-enolase
type: ProteinReference
xref: uniprot G2HFA5 118
xref: PTHR11902:SF12
organism: Pan troglodytes

Fructose-bisphosphate aldolase A
type: ProteinReference
xref: uniprot P04075 141
xref: PTHR11627:SF1
organism: Homo sapiens

Uncharacterized protein
type: ProteinReference
xref: uniprot M0R3X7 101
organism: Rattus norvegicus

uniprot F6TLQ6 63
type: UnificationXref
id: F6TLQ6
db: uniprot

uniprot F6XLJ9 155
type: UnificationXref
id: F6XLJ9
db: uniprot

uniprot P05064 142
type: UnificationXref
id: P05064
db: uniprot

uniprot P17183 128
type: UnificationXref
id: P17183
db: uniprot

STATE_TRANSITION_LEFT__Phosphoenolpyruvate-_2_ADP-RIGHT__2_ATP-_Pyruvate-_r19
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r19 184
participant stoichiometry: PARTICIPANT STOICHIOMETRY r19 183
participant stoichiometry: PARTICIPANT STOICHIOMETRY r19 185
participant stoichiometry: PARTICIPANT STOICHIOMETRY r19 186
left: 2 ADP
left: Phosphoenolpyruvate
interaction type: STATE_TRANSITION
right: Pyruvate
right: 2 ATP

uniprot A0A2I3TJX5 62
type: UnificationXref
id: A0A2I3TJX5
db: uniprot

uniprot Q12008 172
type: UnificationXref
id: Q12008
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F1PNI3 138
xref: PTHR11627:SF1
organism: Canis lupus familiaris

STATE_TRANSITION_LEFT__Dihydroxyacetone_phosphate-RIGHT__Glyceraldehyde_3_phosphate-_r12
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r12 202
participant stoichiometry: PARTICIPANT STOICHIOMETRY r12 203
left: Dihydroxyacetone phosphate
interaction type: STATE_TRANSITION
right: Glyceraldehyde 3-phosphate

uniprot P16290 164
type: UnificationXref
id: P16290
db: uniprot

uniprot A0A1D5QYR2 37
type: UnificationXref
id: A0A1D5QYR2
db: uniprot

Phosphoglycerate mutase
type: ProteinReference
xref: PTHR11931:SF11
xref: uniprot E1B959 151
organism: Bos taurus

ncbitaxon 10090 15
type: UnificationXref
id: 10090
db: ncbitaxon

ATP-dependent 6-phosphofructokinase, muscle type
type: ProteinReference
xref: uniprot P08237 44
organism: Homo sapiens

Triosephosphate isomerase
type: ProteinReference
xref: uniprot P17751 55
organism: Mus musculus

uniprot P16617 16
type: UnificationXref
id: P16617
db: uniprot

Putative hexokinase HKDC1
type: ProteinReference
xref: uniprot Q2TB90 107
organism: Homo sapiens

uniprot Q8TN93 177
type: UnificationXref
id: Q8TN93
db: uniprot

uniprot F6SW40 8
type: UnificationXref
id: F6SW40
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__ATP-_Fructose_6_phosphate-RIGHT__ADP-_Fructose_1,_6_bisphosphate-_r9
controller: Phosphofructokinase-1

ncbitaxon 83333 54
type: UnificationXref
id: 83333
db: ncbitaxon

Phosphofructokinase-1
type: Protein
entity reference: Phosphofructokinase-1
comment: SPECIES_TYPE=PROTEIN

uniprot P17182 127
type: UnificationXref
id: P17182
db: uniprot

ATP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ATP-dependent 6-phosphofructokinase 2
type: ProteinReference
xref: uniprot Q55988 50
xref: PTHR13697:SF52
organism: Synechocystis

uniprot Q12326 173
type: UnificationXref
id: Q12326
db: uniprot

PTHR11406:SF0
type: RelationshipXref
id: PTHR11406:SF0
db: PANTHER Family
relationship type: By Homology

uniprot Q9DBJ1 178
type: UnificationXref
id: Q9DBJ1
db: uniprot

Fructose 1, 6-bisphosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Pyruvate kinase
type: Protein
entity reference: Pyruvate kinase
comment: SPECIES_TYPE=PROTEIN

uniprot Q7Q850 31
type: UnificationXref
id: Q7Q850
db: uniprot

ATP-dependent 6-phosphofructokinase
type: ProteinReference
xref: uniprot F6WXS8 38
organism: Macaca mulatta

Fructose-bisphosphate aldolase
type: ProteinReference
xref: uniprot A6ZI46 136
xref: PTHR11627:SF1
organism: Mus musculus

uniprot Q8JH70 150
type: UnificationXref
id: Q8JH70
db: uniprot

Triosephosphate isomerase
type: ProteinReference
xref: uniprot P29613 56
organism: Drosophila melanogaster

uniprot A5A6I5 135
type: UnificationXref
id: A5A6I5
db: uniprot

ncbitaxon 3702 61
type: UnificationXref
id: 3702
db: ncbitaxon

STATE_TRANSITION_LEFT__Glucose-_ATP-RIGHT__Glucose_6_phosphate-_ADP-_r5
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 179
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 180
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 182
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 181
left: Glucose
left: ATP
interaction type: STATE_TRANSITION
right: Glucose 6-phosphate
right: ADP

uniprot P07323 123
type: UnificationXref
id: P07323
db: uniprot

uniprot H2Q205 99
type: UnificationXref
id: H2Q205
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__1,_3_Bisphosphoglycerate-_2_ADP-RIGHT__2_ATP-_3_Phosphoglycerate-_r16
controller: Phosphoglycerate kinase

PTHR11817:SF63
type: RelationshipXref
id: PTHR11817:SF63
db: PANTHER Family
relationship type: By Homology

Fructose-bisphosphate aldolase C-B
type: ProteinReference
xref: PTHR11627:SF3
xref: uniprot Q8JH70 150
organism: Danio rerio

Pyruvate kinase
type: ProteinReference
xref: P00675
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Pyruvate kinase Synonym: Synonym not specified Accession: P00675
comment: ENTITY_REFERENCE_ID_DESC=Glycolysis.PROTEIN.GENERIC.Pyruvate kinase
member entity reference: Pyruvate kinase PKLR
member entity reference: Pyruvate kinase PKM
member entity reference: Pyruvate kinase
member entity reference: Plastidial pyruvate kinase 2
member entity reference: Plastidial pyruvate kinase 1, chloroplastic
member entity reference: Plastidial pyruvate kinase 3, chloroplastic

2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
type: ProteinReference
xref: PTHR11931:SF0
xref: uniprot P62707 169
organism: Escherichia coli

PTHR11902:SF47
type: RelationshipXref
id: PTHR11902:SF47
db: PANTHER Family
relationship type: By Homology

uniprot Q91W97 108
type: UnificationXref
id: Q91W97
db: uniprot

Plastidial pyruvate kinase 1, chloroplastic
type: ProteinReference
xref: uniprot Q9LIK0 84
xref: PTHR11817:SF14
organism: Arabidopsis thaliana

Enolase 1a, (alpha)
type: ProteinReference
xref: uniprot A0A2R8Q1X2 110
xref: PTHR11902:SF44
organism: Danio rerio

2 H2O
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q9XSJ4 133
type: UnificationXref
id: Q9XSJ4
db: uniprot

PTHR11902:SF44
type: RelationshipXref
id: PTHR11902:SF44
db: PANTHER Family
relationship type: By Homology

Pyruvate kinase PKM
type: ProteinReference
xref: uniprot P14618 76
organism: Homo sapiens

uniprot P07738 161
type: UnificationXref
id: P07738
db: uniprot

Glyceraldehyde-3-phosphate dehydrogenase
type: ProteinReference
xref: PTHR43454:SF1
xref: uniprot Q9FC43 95
organism: Streptomyces coelicolor

Bacillus subtilis
type: BioSource
xref: ncbitaxon 224308 26

Hexokinase domain containing 1
type: ProteinReference
xref: uniprot H2Q205 99
organism: Pan troglodytes

Alpha-enolase
type: ProteinReference
xref: PTHR11902:SF12
xref: uniprot Q9XSJ4 133
organism: Bos taurus

Phosphoglycerate mutase 1
type: ProteinReference
xref: PTHR11931:SF0
xref: uniprot P00950 160
organism: Saccharomyces cerevisiae

Bos taurus
type: BioSource
xref: ncbitaxon 9913 30

Macaca mulatta
type: BioSource
xref: ncbitaxon 9544 7

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Glucose-_ATP-RIGHT__Glucose_6_phosphate-_ADP-_r5
controller: Hexokinase

uniprot E1B959 151
type: UnificationXref
id: E1B959
db: uniprot

PTHR13697:SF52
type: RelationshipXref
id: PTHR13697:SF52
db: PANTHER Family
relationship type: By Homology

Ornithorhynchus anatinus
type: BioSource
xref: ncbitaxon 9258 117

ncbitaxon 9615 3
type: UnificationXref
id: 9615
db: ncbitaxon

Triosephosphate isomerase
type: ProteinReference
xref: uniprot P60174 59
organism: Homo sapiens

PARTICIPANT STOICHIOMETRY r16 192
type: Stoichiometry
physical entity: 1, 3-Bisphosphoglycerate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r16 194
type: Stoichiometry
physical entity: 2 ATP
stoichiometric coefficient: 1.0

Alpha-enolase
type: ProteinReference
xref: PTHR11902:SF12
xref: uniprot P51913 132
organism: Gallus gallus

PARTICIPANT STOICHIOMETRY r16 193
type: Stoichiometry
physical entity: 2 ADP
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r16 195
type: Stoichiometry
physical entity: 3-Phosphoglycerate
stoichiometric coefficient: 1.0

3-Phosphoglycerate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Phosphoglycerate kinase
type: ProteinReference
xref: PTHR11406:SF0
xref: uniprot P29407 20
organism: Yarrowia lipolytica

Triosephosphate isomerase
type: ProteinReference
xref: uniprot P00942 51
organism: Saccharomyces cerevisiae

Fructose-bisphosphate aldolase
type: ProteinReference
xref: PTHR11627:SF1
xref: uniprot A6ZI47 137
organism: Mus musculus

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Fructose_1,_6_bisphosphate-RIGHT__Dihydroxyacetone_phosphate-_r10
controller: Aldolase

uniprot P00950 160
type: UnificationXref
id: P00950
db: uniprot

ATP-dependent 6-phosphofructokinase, liver type
type: ProteinReference
xref: uniprot P12382 45
organism: Mus musculus

Phosphoglycerate kinase
type: ProteinReference
xref: uniprot F6VB69 10
xref: PTHR11406:SF0
organism: Monodelphis domestica

uniprot P9WIC9 170
type: UnificationXref
id: P9WIC9
db: uniprot

Methanosarcina acetivorans
type: BioSource
xref: ncbitaxon 188937 34

1, 3-Bisphosphoglycerate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PTHR19443:SF10
type: RelationshipXref
id: PTHR19443:SF10
db: PANTHER Family
relationship type: By Homology

uniprot P40924 25
type: UnificationXref
id: P40924
db: uniprot

uniprot Q8RFG9 175
type: UnificationXref
id: Q8RFG9
db: uniprot

uniprot P42862 68
type: UnificationXref
id: P42862
db: uniprot

ncbitaxon 100226 65
type: UnificationXref
id: 100226
db: ncbitaxon

uniprot F6SFZ4 6
type: UnificationXref
id: F6SFZ4
db: uniprot

uniprot H2RBP4 74
type: UnificationXref
id: H2RBP4
db: uniprot

Enolase
type: Protein
entity reference: Enolase
comment: SPECIES_TYPE=PROTEIN

uniprot P12928 75
type: UnificationXref
id: P12928
db: uniprot

Aquifex aeolicus
type: BioSource
xref: ncbitaxon 224324 43

Phosphoglycerate mutase 2
type: ProteinReference
xref: uniprot Q12008 172
xref: PTHR11931:SF9
organism: Saccharomyces cerevisiae

PARTICIPANT STOICHIOMETRY r9 209
type: Stoichiometry
physical entity: Fructose 6-phosphate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r9 208
type: Stoichiometry
physical entity: ATP
stoichiometric coefficient: 1.0

Canis lupus familiaris
type: BioSource
xref: ncbitaxon 9615 3

Fructose-bisphosphate aldolase
type: ProteinReference
xref: uniprot P07764 145
xref: PTHR11627:SF42
organism: Drosophila melanogaster

PTHR11817:SF2
type: RelationshipXref
id: PTHR11817:SF2
db: PANTHER Family
relationship type: By Homology

uniprot P06744 66
type: UnificationXref
id: P06744
db: uniprot

uniprot P16858 92
type: UnificationXref
id: P16858
db: uniprot

Fructose-bisphosphate aldolase
type: ProteinReference
xref: uniprot F7E0Q7 140
xref: PTHR11627:SF1
organism: Monodelphis domestica

Fructose-bisphosphate aldolase
type: ProteinReference
xref: uniprot F6SYJ3 139
xref: PTHR11627:SF1
organism: Macaca mulatta

Phosphoglycerate mutase 2
type: ProteinReference
xref: uniprot O70250 157
organism: Mus musculus

Phosphoglycerate mutase
type: ProteinReference
xref: PTHR11931:SF11
xref: uniprot F1MX69 153
organism: Bos taurus

Phosphoglycerate mutase
type: ProteinReference
xref: PTHR11931:SF11
xref: uniprot F6Q944 154
organism: Macaca mulatta

uniprot P12382 45
type: UnificationXref
id: P12382
db: uniprot

PTHR11902:SF12
type: RelationshipXref
id: PTHR11902:SF12
db: PANTHER Family
relationship type: By Homology

uniprot P30613 77
type: UnificationXref
id: P30613
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__2_NAD_PLUS___PLUS__2_Pi-_Glyceraldehyde_3_phosphate-RIGHT__2_NADH__PLUS__2_H_PLUS_-_1,_3_Bisphosphoglycerate-_r14
controller: Glyceraldehyde 3-phosphate dehydrogenase

PTHR11902:SF10
type: RelationshipXref
id: PTHR11902:SF10
db: PANTHER Family
relationship type: By Homology

Gallus gallus
type: BioSource
xref: ncbitaxon 9031 120

Phosphoglucose isomerase
type: ProteinReference
xref: P00674
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Phosphoglucose isomerase Synonym: Synonym not specified Accession: P00674
comment: ENTITY_REFERENCE_ID_DESC=Glycolysis.PROTEIN.GENERIC.Phosphoglucose_br_isomerase
member entity reference: Glucose-6-phosphate isomerase 1
member entity reference: Glucose-6-phosphate isomerase, cytosolic B
member entity reference: Glucose-6-phosphate isomerase 2
member entity reference: Glucose-6-phosphate isomerase
member entity reference: Glucose-6-phosphate isomerase, cytosolic A

PARTICIPANT STOICHIOMETRY r9 210
type: Stoichiometry
physical entity: ADP
stoichiometric coefficient: 1.0

Pyrobaculum aerophilum
type: BioSource
xref: ncbitaxon 178306 36

PARTICIPANT STOICHIOMETRY r9 211
type: Stoichiometry
physical entity: Fructose 1, 6-bisphosphate
stoichiometric coefficient: 1.0

uniprot Q55988 50
type: UnificationXref
id: Q55988
db: uniprot

Glyceraldehyde 3-phosphate dehydrogenase
type: ProteinReference
xref: P00676
comment: ENTITY_REFERENCE_ID_DESC=Glycolysis.PROTEIN.GENERIC.Glyceraldehyde_br_3-phosphate_br_dehydrogenase
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Glyceraldehyde 3-phosphate dehydrogenase Synonym: Synonym not specified Accession: P00676
member entity reference: Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic
member entity reference: Glyceraldehyde-3-phosphate dehydrogenase 2
member entity reference: Glyceraldehyde-3-phosphate dehydrogenase 1
member entity reference: Glyceraldehyde-3-phosphate dehydrogenase
member entity reference: Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic
member entity reference: Glyceraldehyde-3-phosphate dehydrogenase A

uniprot H2QVE8 156
type: UnificationXref
id: H2QVE8
db: uniprot

Phosphoglyceromutase
type: Protein
entity reference: Phosphoglyceromutase
comment: SPECIES_TYPE=PROTEIN

uniprot Q6NVQ9 149
type: UnificationXref
id: Q6NVQ9
db: uniprot

Streptomyces coelicolor
type: BioSource
xref: ncbitaxon 100226 65

uniprot P29613 56
type: UnificationXref
id: P29613
db: uniprot

ATP-dependent 6-phosphofructokinase, muscle type
type: ProteinReference
xref: uniprot P47857 48
organism: Mus musculus

ATP-dependent 6-phosphofructokinase, muscle type
type: ProteinReference
xref: uniprot P47858 49
organism: Rattus norvegicus

Phosphoglycerate kinase 2
type: ProteinReference
xref: uniprot Q8TK32 33
xref: PTHR11406:SF23
organism: Methanosarcina acetivorans

uniprot M0R3X7 101
type: UnificationXref
id: M0R3X7
db: uniprot

uniprot P51913 132
type: UnificationXref
id: P51913
db: uniprot

Hexokinase-2
type: ProteinReference
xref: uniprot O08528 102
organism: Mus musculus

STATE_TRANSITION
type: RelationshipTypeVocabulary

uniprot P0A858 53
type: UnificationXref
id: P0A858
db: uniprot

uniprot Q6AY07 148
type: UnificationXref
id: Q6AY07
db: uniprot

PARTICIPANT STOICHIOMETRY r14 199
type: Stoichiometry
physical entity: 1, 3-Bisphosphoglycerate
stoichiometric coefficient: 1.0

Enolase-related protein 3
type: ProteinReference
xref: PTHR11902:SF1
xref: uniprot P42222 131
organism: Saccharomyces cerevisiae

Uncharacterized protein
type: ProteinReference
xref: PTHR19443:SF10
xref: uniprot F6Q724 96
organism: Macaca mulatta

Phosphoglycerate mutase 3
type: ProteinReference
xref: PTHR11931:SF9
xref: uniprot Q12326 173
organism: Saccharomyces cerevisiae

uniprot Q9Z523 72
type: UnificationXref
id: Q9Z523
db: uniprot

PARTICIPANT STOICHIOMETRY r14 198
type: Stoichiometry
physical entity: 2 NADH + 2 H+
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r19 184
type: Stoichiometry
physical entity: 2 ADP
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r14 197
type: Stoichiometry
physical entity: Glyceraldehyde 3-phosphate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r19 183
type: Stoichiometry
physical entity: Phosphoenolpyruvate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r14 196
type: Stoichiometry
physical entity: 2 NAD+ + 2 Pi
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r19 186
type: Stoichiometry
physical entity: Pyruvate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r19 185
type: Stoichiometry
physical entity: 2 ATP
stoichiometric coefficient: 1.0

uniprot F7FI39 73
type: UnificationXref
id: F7FI39
db: uniprot

Glyceraldehyde 3-phosphate dehydrogenase
type: Protein
entity reference: Glyceraldehyde 3-phosphate dehydrogenase
comment: SPECIES_TYPE=PROTEIN

uniprot P25856 93
type: UnificationXref
id: P25856
db: uniprot

uniprot F7FAQ8 116
type: UnificationXref
id: F7FAQ8
db: uniprot

PTHR11406:SF14
type: RelationshipXref
id: PTHR11406:SF14
db: PANTHER Family
relationship type: By Homology

uniprot P48500 58
type: UnificationXref
id: P48500
db: uniprot

Bisphosphoglycerate mutase
type: ProteinReference
xref: PTHR11931:SF11
xref: uniprot P15327 163
organism: Mus musculus

uniprot P33158 166
type: UnificationXref
id: P33158
db: uniprot

Eno1 protein
type: ProteinReference
xref: PTHR11902:SF12
xref: uniprot B0BMH7 113
organism: Xenopus tropicalis

Plastidial pyruvate kinase 3, chloroplastic
type: ProteinReference
xref: PTHR11817:SF63
xref: uniprot Q93Z53 81
organism: Arabidopsis thaliana

Bisphosphoglycerate mutase
type: ProteinReference
xref: PTHR11931:SF11
xref: uniprot P07738 161
organism: Homo sapiens

ncbitaxon 10116 17
type: UnificationXref
id: 10116
db: ncbitaxon

ncbitaxon 367110 24
type: UnificationXref
id: 367110
db: ncbitaxon

Phosphoglycerate mutase 2
type: ProteinReference
xref: uniprot P15259 162
organism: Homo sapiens

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__2_Phosphoglycerate-RIGHT__2_H2O-_Phosphoenolpyruvate-_r18
controller: Enolase

Caenorhabditis elegans
type: BioSource
xref: ncbitaxon 6239 88

Fructose-bisphosphate aldolase
type: ProteinReference
xref: PTHR11627:SF3
xref: uniprot Q6NVQ9 149
organism: Xenopus tropicalis

Alpha-enolase
type: ProteinReference
xref: PTHR11902:SF12
xref: uniprot P04764 121
organism: Rattus norvegicus

Phosphoglycerate kinase
type: ProteinReference
xref: uniprot Q8ZWK6 35
xref: PTHR11406:SF23
organism: Pyrobaculum aerophilum

PTHR11406:SF23
type: RelationshipXref
id: PTHR11406:SF23
db: PANTHER Family
relationship type: By Homology

uniprot P07487 90
type: UnificationXref
id: P07487
db: uniprot

Plastidial pyruvate kinase 2
type: ProteinReference
xref: uniprot Q9FLW9 83
xref: PTHR11817:SF2
organism: Arabidopsis thaliana

Triosephosphate isomerase
type: ProteinReference
xref: uniprot P0A858 53
organism: Escherichia coli

Phosphoglycerate kinase
type: ProteinReference
xref: uniprot P74421 27
xref: PTHR11406:SF23
organism: Synechocystis

ncbitaxon 190304 176
type: UnificationXref
id: 190304
db: ncbitaxon

uniprot P06745 67
type: UnificationXref
id: P06745
db: uniprot

uniprot G2HFA5 118
type: UnificationXref
id: G2HFA5
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Phosphoenolpyruvate-_2_ADP-RIGHT__2_ATP-_Pyruvate-_r19
controller: Pyruvate kinase

Gamma-enolase
type: ProteinReference
xref: PTHR11902:SF10
xref: uniprot F6X1V9 115
organism: Macaca mulatta

Hexokinase-1
type: ProteinReference
xref: PTHR19443:SF10
xref: uniprot P19367 104
organism: Homo sapiens

uniprot P0A6P9 125
type: UnificationXref
id: P0A6P9
db: uniprot

uniprot Q8N0Y7 174
type: UnificationXref
id: Q8N0Y7
db: uniprot

uniprot P25858 94
type: UnificationXref
id: P25858
db: uniprot

ncbitaxon 7165 32
type: UnificationXref
id: 7165
db: ncbitaxon

Fructose-bisphosphate aldolase
type: ProteinReference
xref: uniprot Q6AY07 148
xref: PTHR11627:SF1
organism: Rattus norvegicus

Oryza sativa
type: BioSource
xref: ncbitaxon 39947 69

ncbitaxon 83332 171
type: UnificationXref
id: 83332
db: ncbitaxon

STATE_TRANSITION_LEFT__Fructose_1,_6_bisphosphate-RIGHT__Glyceraldehyde_3_phosphate-_r11
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r11 205
participant stoichiometry: PARTICIPANT STOICHIOMETRY r11 204
left: Fructose 1, 6-bisphosphate
interaction type: STATE_TRANSITION
right: Glyceraldehyde 3-phosphate

eco ECO:0000305 130
type: UnificationXref
id: ECO:0000305
db: eco

uniprot Q9SAJ4 60
type: UnificationXref
id: Q9SAJ4
db: uniprot

Fructose-bisphosphate aldolase
type: ProteinReference
xref: uniprot A0A3Q1LMG1 134
xref: PTHR11627:SF1
organism: Bos taurus

Dihydroxyacetone phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Glyceraldehyde-3-phosphate dehydrogenase
type: ProteinReference
xref: uniprot P04797 86
organism: Rattus norvegicus

uniprot P47857 48
type: UnificationXref
id: P47857
db: uniprot

uniprot P52480 78
type: UnificationXref
id: P52480
db: uniprot

uniprot E2RRC9 2
type: UnificationXref
id: E2RRC9
db: uniprot

uniprot P14618 76
type: UnificationXref
id: P14618
db: uniprot

Phosphoglycerate kinase
type: ProteinReference
xref: uniprot P38667 23
xref: PTHR11406:SF0
organism: Neurospora crassa

uniprot P42222 131
type: UnificationXref
id: P42222
db: uniprot

Anopheles gambiae
type: BioSource
xref: ncbitaxon 7165 32

2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
type: ProteinReference
xref: PTHR11931:SF0
xref: uniprot Q8TN93 177
organism: Methanosarcina acetivorans

uniprot A0A2R8Q1X2 110
type: UnificationXref
id: A0A2R8Q1X2
db: uniprot

uniprot F1PNI3 138
type: UnificationXref
id: F1PNI3
db: uniprot

uniprot A6ZI46 136
type: UnificationXref
id: A6ZI46
db: uniprot

ATP-dependent 6-phosphofructokinase
type: ProteinReference
xref: uniprot O67605 42
xref: PTHR13697:SF4
organism: Aquifex aeolicus

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Glucose_6_phosphate-RIGHT__Fructose_6_phosphate-_r6
controller: Phosphoglucose isomerase

Chlamydia trachomatis
type: BioSource
xref: ncbitaxon 272561 159

ncbitaxon 9544 7
type: UnificationXref
id: 9544
db: ncbitaxon

uniprot P07341 144
type: UnificationXref
id: P07341
db: uniprot

ncbitaxon 284812 168
type: UnificationXref
id: 284812
db: ncbitaxon

Pyruvate kinase PKLR
type: ProteinReference
xref: uniprot P12928 75
organism: Rattus norvegicus

uniprot O67605 42
type: UnificationXref
id: O67605
db: uniprot

Synechocystis
type: BioSource
xref: ncbitaxon 1111708 28

PARTICIPANT STOICHIOMETRY r13 201
type: Stoichiometry
physical entity: Dihydroxyacetone phosphate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r13 200
type: Stoichiometry
physical entity: Glyceraldehyde 3-phosphate
stoichiometric coefficient: 1.0

ISS
type: EvidenceCodeVocabulary
xref: eco ECO:0000250 4

uniprot P06733 122
type: UnificationXref
id: P06733
db: uniprot

Hexokinase-2
type: ProteinReference
xref: uniprot P27881 105
organism: Rattus norvegicus

uniprot F1MX69 153
type: UnificationXref
id: F1MX69
db: uniprot

uniprot Q8TK32 33
type: UnificationXref
id: Q8TK32
db: uniprot

Phosphoglycerate mutase 1
type: ProteinReference
xref: uniprot Q9DBJ1 178
organism: Mus musculus

Pyruvate kinase PKM
type: ProteinReference
xref: uniprot P52480 78
organism: Mus musculus

Phosphoglycerate kinase 3, cytosolic
type: ProteinReference
xref: uniprot Q9SAJ4 60
organism: Arabidopsis thaliana

PTHR11902:SF1
type: RelationshipXref
id: PTHR11902:SF1
db: PANTHER Family
relationship type: By Homology

PARTICIPANT STOICHIOMETRY r12 203
type: Stoichiometry
physical entity: Glyceraldehyde 3-phosphate
stoichiometric coefficient: 1.0

uniprot P04075 141
type: UnificationXref
id: P04075
db: uniprot

PARTICIPANT STOICHIOMETRY r12 202
type: Stoichiometry
physical entity: Dihydroxyacetone phosphate
stoichiometric coefficient: 1.0

ncbitaxon 8364 114
type: UnificationXref
id: 8364
db: ncbitaxon

Phosphoenolpyruvate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
type: ProteinReference
xref: uniprot O84727 158
xref: PTHR11931:SF0
organism: Chlamydia trachomatis

Phosphoglycerate kinase
type: ProteinReference
xref: uniprot P40924 25
xref: PTHR11406:SF23
organism: Bacillus subtilis

uniprot H2QI73 100
type: UnificationXref
id: H2QI73
db: uniprot

uniprot F6VB69 10
type: UnificationXref
id: F6VB69
db: uniprot

Phosphoglycerate mutase
type: ProteinReference
xref: PTHR11931:SF11
xref: uniprot E2QYX1 152
organism: Canis lupus familiaris

Monodelphis domestica
type: BioSource
xref: ncbitaxon 13616 9

uniprot F6Q944 154
type: UnificationXref
id: F6Q944
db: uniprot

PTHR43454:SF1
type: RelationshipXref
id: PTHR43454:SF1
db: PANTHER Family
relationship type: By Homology

Hexokinase 2
type: ProteinReference
xref: uniprot H2QI73 100
organism: Pan troglodytes

uniprot A6QR19 112
type: UnificationXref
id: A6QR19
db: uniprot

uniprot P62707 169
type: UnificationXref
id: P62707
db: uniprot

Glyceraldehyde-3-phosphate dehydrogenase
type: ProteinReference
xref: uniprot P04406 85
organism: Homo sapiens

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Fructose_1,_6_bisphosphate-RIGHT__Glyceraldehyde_3_phosphate-_r11
controller: Aldolase

Schizosaccharomyces pombe
type: BioSource
xref: ncbitaxon 284812 168

uniprot P74421 27
type: UnificationXref
id: P74421
db: uniprot

Phosphoglycerate kinase
type: Protein
entity reference: Phosphoglycerate kinase
comment: SPECIES_TYPE=PROTEIN

Triosephosphate isomerase
type: ProteinReference
xref: uniprot P48500 58
organism: Rattus norvegicus

PTHR11817:SF14
type: RelationshipXref
id: PTHR11817:SF14
db: PANTHER Family
relationship type: By Homology

PTHR11931:SF11
type: RelationshipXref
id: PTHR11931:SF11
db: PANTHER Family
relationship type: By Homology

STATE_TRANSITION_LEFT__Glyceraldehyde_3_phosphate-RIGHT__Dihydroxyacetone_phosphate-_r13
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r13 201
participant stoichiometry: PARTICIPANT STOICHIOMETRY r13 200
left: Glyceraldehyde 3-phosphate
interaction type: STATE_TRANSITION
right: Dihydroxyacetone phosphate

Fructose 6-phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

P00673
type: UnificationXref
id: P00673
db: PANTHER Pathway Component

uniprot E2QYX1 152
type: UnificationXref
id: E2QYX1
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Dihydroxyacetone_phosphate-RIGHT__Glyceraldehyde_3_phosphate-_r12
controller: Triosephosphate isomerase

P00674
type: UnificationXref
id: P00674
db: PANTHER Pathway Component

P00671
type: UnificationXref
id: P00671
db: PANTHER Pathway Component

P00672
type: UnificationXref
id: P00672
db: PANTHER Pathway Component

Enolase
type: ProteinReference
xref: uniprot P0A6P9 125
organism: Escherichia coli

Glyceraldehyde 3-phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot P27362 18
type: UnificationXref
id: P27362
db: uniprot

Glucose-6-phosphate isomerase, cytosolic B
type: ProteinReference
xref: PTHR11469:SF1
xref: uniprot P42863 70
organism: Oryza sativa

Fructose-bisphosphate aldolase A
type: ProteinReference
xref: uniprot P05064 142
xref: PTHR11627:SF1
organism: Mus musculus

Hexokinase-2
type: ProteinReference
xref: uniprot P52789 106
organism: Homo sapiens

Fructose-bisphosphate aldolase A
type: ProteinReference
xref: PTHR11627:SF1
xref: uniprot P05065 143
organism: Rattus norvegicus

Phosphoglycerate kinase
type: ProteinReference
xref: uniprot E2RRC9 2
xref: PTHR11406:SF14
organism: Canis lupus familiaris

ncbitaxon 7955 111
type: UnificationXref
id: 7955
db: ncbitaxon

ncbitaxon 5664 147
type: UnificationXref
id: 5664
db: ncbitaxon

P00680
type: UnificationXref
id: P00680
db: PANTHER Pathway Component

Glucose-6-phosphate isomerase 2
type: ProteinReference
xref: PTHR11469:SF1
xref: uniprot Q9Z523 72
organism: Streptomyces coelicolor

P00676
type: UnificationXref
id: P00676
db: PANTHER Pathway Component

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__3_Phosphoglycerate-RIGHT__2_Phosphoglycerate-_r17
controller: Phosphoglyceromutase

P00675
type: UnificationXref
id: P00675
db: PANTHER Pathway Component

P00678
type: UnificationXref
id: P00678
db: PANTHER Pathway Component

P00677
type: UnificationXref
id: P00677
db: PANTHER Pathway Component

P00679
type: UnificationXref
id: P00679
db: PANTHER Pathway Component

Aldolase
type: ProteinReference
xref: P00679
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Aldolase Synonym: Synonym not specified Accession: P00679
comment: ENTITY_REFERENCE_ID_DESC=Glycolysis.PROTEIN.GENERIC.Aldolase
member entity reference: Fructose-bisphosphate aldolase
member entity reference: Fructose-bisphosphate aldolase A
member entity reference: Fructose-bisphosphate aldolase C-B
member entity reference: Uncharacterized protein
member entity reference: Fructose-bisphosphate aldolase B

STATE_TRANSITION_LEFT__Fructose_1,_6_bisphosphate-RIGHT__Dihydroxyacetone_phosphate-_r10
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r10 206
participant stoichiometry: PARTICIPANT STOICHIOMETRY r10 207
left: Fructose 1, 6-bisphosphate
interaction type: STATE_TRANSITION
right: Dihydroxyacetone phosphate

Homo sapiens
type: BioSource
xref: ncbitaxon 9606 13

uniprot P09411 14
type: UnificationXref
id: P09411
db: uniprot

uniprot P52789 106
type: UnificationXref
id: P52789
db: uniprot

Arabidopsis thaliana
type: BioSource
xref: ncbitaxon 3702 61

uniprot O70250 157
type: UnificationXref
id: O70250
db: uniprot

Phosphoglycerate kinase 1
type: ProteinReference
xref: uniprot P00558 12
xref: PTHR11406:SF14
organism: Homo sapiens

uniprot P0CX11 126
type: UnificationXref
id: P0CX11
db: uniprot

PARTICIPANT STOICHIOMETRY r5 182
type: Stoichiometry
physical entity: ADP
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r5 181
type: Stoichiometry
physical entity: Glucose 6-phosphate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r5 180
type: Stoichiometry
physical entity: ATP
stoichiometric coefficient: 1.0

ncbitaxon 9913 30
type: UnificationXref
id: 9913
db: ncbitaxon

Phosphoglycerate mutase 2
type: ProteinReference
xref: uniprot P16290 164
organism: Rattus norvegicus

Hexokinase
type: Protein
entity reference: Hexokinase
comment: SPECIES_TYPE=PROTEIN

Mycobacterium tuberculosis
type: BioSource
xref: ncbitaxon 83332 171

PARTICIPANT STOICHIOMETRY r5 179
type: Stoichiometry
physical entity: Glucose
stoichiometric coefficient: 1.0

Glucose-6-phosphate isomerase, cytosolic A
type: ProteinReference
xref: PTHR11469:SF1
xref: uniprot P42862 68
organism: Oryza sativa

uniprot P29407 20
type: UnificationXref
id: P29407
db: uniprot

Pyruvate kinase
type: ProteinReference
xref: uniprot H2RBP4 74
organism: Pan troglodytes

Gamma-enolase
type: ProteinReference
xref: PTHR11902:SF10
xref: uniprot O57391 119
organism: Gallus gallus

ADP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

2 ADP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ncbitaxon 224324 43
type: UnificationXref
id: 224324
db: ncbitaxon

Escherichia coli
type: BioSource
xref: ncbitaxon 83333 54

Danio rerio
type: BioSource
xref: ncbitaxon 7955 111

Glucose 6-phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ncbitaxon 6239 88
type: UnificationXref
id: 6239
db: ncbitaxon

Enolase-related protein 2
type: ProteinReference
xref: PTHR11902:SF1
xref: uniprot P0CX11 126
organism: Saccharomyces cerevisiae

Enolase 1
type: ProteinReference
xref: PTHR11902:SF12
xref: uniprot F7FAQ8 116
organism: Ornithorhynchus anatinus

uniprot F7C393 11
type: UnificationXref
id: F7C393
db: uniprot

uniprot P53657 79
type: UnificationXref
id: P53657
db: uniprot

uniprot P04406 85
type: UnificationXref
id: P04406
db: uniprot

ncbitaxon 9031 120
type: UnificationXref
id: 9031
db: ncbitaxon

Phosphoglycerate kinase
type: ProteinReference
xref: uniprot Q7Q850 31
xref: PTHR11406:SF0
organism: Anopheles gambiae

Pyruvate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ncbitaxon 1111708 28
type: UnificationXref
id: 1111708
db: ncbitaxon

uniprot P05065 143
type: UnificationXref
id: P05065
db: uniprot

2 NADH + 2 H+
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ncbitaxon 559292 52
type: UnificationXref
id: 559292
db: ncbitaxon

IDA
type: EvidenceCodeVocabulary

ATP-dependent 6-phosphofructokinase, liver type
type: ProteinReference
xref: uniprot P30835 47
organism: Rattus norvegicus

eco ECO:0000250 4
type: UnificationXref
id: ECO:0000250
db: eco

uniprot P04970 87
type: UnificationXref
id: P04970
db: uniprot

Fusobacterium nucleatum
type: BioSource
xref: ncbitaxon 190304 176

2-Phosphoglycerate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Enolase
type: ProteinReference
xref: P00678
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Glycolysis.PROTEIN.GENERIC.Enolase
comment: ENTITY_REFERENCE_NOTES=Long Name: Enolase Synonym: Phosphopyruvate hydratase Accession: P00678
member entity reference: Enolase-related protein 2
member entity reference: Enolase
member entity reference: Alpha-enolase
member entity reference: Gamma-enolase
member entity reference: Bifunctional enolase 2/transcriptional activator
member entity reference: ENO2 protein
member entity reference: Enolase-related protein 3
member entity reference: Eno1 protein
member entity reference: Enolase 1a, (alpha)
member entity reference: Enolase 1

Phosphoglycerate mutase
type: ProteinReference
xref: uniprot H2QVE8 156
xref: PTHR11931:SF11
organism: Pan troglodytes

STATE_TRANSITION_LEFT__2_Phosphoglycerate-RIGHT__2_H2O-_Phosphoenolpyruvate-_r18
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r18 187
participant stoichiometry: PARTICIPANT STOICHIOMETRY r18 189
participant stoichiometry: PARTICIPANT STOICHIOMETRY r18 188
left: 2-Phosphoglycerate
interaction type: STATE_TRANSITION
right: 2 H2O
right: Phosphoenolpyruvate

uniprot F6WXS8 38
type: UnificationXref
id: F6WXS8
db: uniprot

uniprot P04764 121
type: UnificationXref
id: P04764
db: uniprot

uniprot Q8ZWK6 35
type: UnificationXref
id: Q8ZWK6
db: uniprot

Glucose
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot P25113 165
type: UnificationXref
id: P25113
db: uniprot

STATE_TRANSITION_LEFT__2_NAD_PLUS___PLUS__2_Pi-_Glyceraldehyde_3_phosphate-RIGHT__2_NADH__PLUS__2_H_PLUS_-_1,_3_Bisphosphoglycerate-_r14
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r14 197
participant stoichiometry: PARTICIPANT STOICHIOMETRY r14 198
participant stoichiometry: PARTICIPANT STOICHIOMETRY r14 196
participant stoichiometry: PARTICIPANT STOICHIOMETRY r14 199
left: Glyceraldehyde 3-phosphate
left: 2 NAD+ + 2 Pi
interaction type: STATE_TRANSITION
right: 1, 3-Bisphosphoglycerate
right: 2 NADH + 2 H+

ATP-dependent 6-phosphofructokinase, liver type
type: ProteinReference
xref: uniprot P17858 46
organism: Homo sapiens

IC
type: EvidenceCodeVocabulary
xref: eco ECO:0000305 130

TAS
type: EvidenceCodeVocabulary
xref: eco ECO:0000304 82

uniprot O08528 102
type: UnificationXref
id: O08528
db: uniprot

Phosphoglycerate mutase
type: ProteinReference
xref: PTHR11931:SF11
xref: uniprot F6XLJ9 155
organism: Monodelphis domestica

eco ECO:0000304 82
type: UnificationXref
id: ECO:0000304
db: eco

uniprot F6Q724 96
type: UnificationXref
id: F6Q724
db: uniprot

Glucose-6-phosphate isomerase
type: ProteinReference
xref: uniprot A0A2I3TJX5 62
organism: Pan troglodytes

Putative hexokinase HKDC1
type: ProteinReference
xref: uniprot Q91W97 108
organism: Mus musculus

ncbitaxon 7227 57
type: UnificationXref
id: 7227
db: ncbitaxon

PTHR11627:SF3
type: RelationshipXref
id: PTHR11627:SF3
db: PANTHER Family
relationship type: By Homology

uniprot P19367 104
type: UnificationXref
id: P19367
db: uniprot

PTHR11627:SF2
type: RelationshipXref
id: PTHR11627:SF2
db: PANTHER Family
relationship type: By Homology

Glucose-6-phosphate isomerase
type: ProteinReference
xref: uniprot P06744 66
organism: Homo sapiens

Glyceraldehyde-3-phosphate dehydrogenase
type: ProteinReference
xref: uniprot P16858 92
organism: Mus musculus

Glucose-6-phosphate isomerase
type: ProteinReference
xref: uniprot P06745 67
organism: Mus musculus

PTHR11627:SF1
type: RelationshipXref
id: PTHR11627:SF1
db: PANTHER Family
relationship type: By Homology

Glucose-6-phosphate isomerase
type: ProteinReference
xref: uniprot F6TLQ6 63
organism: Macaca mulatta

ncbitaxon 188937 34
type: UnificationXref
id: 188937
db: ncbitaxon

uniprot P30835 47
type: UnificationXref
id: P30835
db: uniprot

Phosphoglycerate kinase
type: ProteinReference
xref: P00671
comment: ENTITY_REFERENCE_NOTES=Long Name: Phosphoglycerate kinase Synonym: Synonym not specified Accession: P00671
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Glycolysis.PROTEIN.GENERIC.Phosphoglycerate_br_kinase
member entity reference: Phosphoglycerate kinase 1
member entity reference: Phosphoglycerate kinase
member entity reference: Phosphoglycerate kinase 2

Fructose-bisphosphate aldolase B
type: ProteinReference
xref: uniprot P07341 144
xref: PTHR11627:SF2
organism: Gallus gallus

uniprot O57391 119
type: UnificationXref
id: O57391
db: uniprot

Pyruvate kinase
type: ProteinReference
xref: uniprot F7FI39 73
organism: Macaca mulatta

Glyceraldehyde-3-phosphate dehydrogenase 1
type: ProteinReference
xref: uniprot P07486 89
organism: Drosophila melanogaster

Glyceraldehyde-3-phosphate dehydrogenase 2
type: ProteinReference
xref: uniprot P07487 90
organism: Drosophila melanogaster

Rattus norvegicus
type: BioSource
xref: ncbitaxon 10116 17

Alpha-enolase
type: ProteinReference
xref: PTHR11902:SF12
xref: uniprot P06733 122
organism: Homo sapiens

Gamma-enolase
type: ProteinReference
xref: PTHR11902:SF10
xref: uniprot P09104 124
organism: Homo sapiens

Pyruvate kinase PKLR
type: ProteinReference
xref: uniprot P53657 79
organism: Mus musculus

uniprot P07764 145
type: UnificationXref
id: P07764
db: uniprot

uniprot P17751 55
type: UnificationXref
id: P17751
db: uniprot

Aldolase
type: Protein
entity reference: Aldolase
comment: SPECIES_TYPE=PROTEIN

Fructose-bisphosphate aldolase
type: ProteinReference
xref: uniprot Q4Q1V0 146
xref: PTHR11627:SF42
organism: Leishmania major

Bifunctional enolase 2/transcriptional activator
type: ProteinReference
xref: PTHR11902:SF47
xref: uniprot P25696 129
organism: Arabidopsis thaliana

2 NAD+ + 2 Pi
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r18 187
type: Stoichiometry
physical entity: 2-Phosphoglycerate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r18 188
type: Stoichiometry
physical entity: 2 H2O
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r18 189
type: Stoichiometry
physical entity: Phosphoenolpyruvate
stoichiometric coefficient: 1.0

2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
type: ProteinReference
xref: uniprot P33158 166
xref: PTHR11931:SF0
organism: Streptomyces coelicolor

uniprot Q9LIK0 84
type: UnificationXref
id: Q9LIK0
db: uniprot

PARTICIPANT STOICHIOMETRY r11 204
type: Stoichiometry
physical entity: Fructose 1, 6-bisphosphate
stoichiometric coefficient: 1.0

STATE_TRANSITION_LEFT__3_Phosphoglycerate-RIGHT__2_Phosphoglycerate-_r17
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r17 191
participant stoichiometry: PARTICIPANT STOICHIOMETRY r17 190
left: 3-Phosphoglycerate
interaction type: STATE_TRANSITION
right: 2-Phosphoglycerate

PARTICIPANT STOICHIOMETRY r11 205
type: Stoichiometry
physical entity: Glyceraldehyde 3-phosphate
stoichiometric coefficient: 1.0

uniprot K7AUT0 39
type: UnificationXref
id: K7AUT0
db: uniprot

ncbitaxon 9258 117
type: UnificationXref
id: 9258
db: ncbitaxon

uniprot Q9FLW9 83
type: UnificationXref
id: Q9FLW9
db: uniprot

STATE_TRANSITION
type: InteractionVocabulary

Phosphofructokinase-1
type: ProteinReference
xref: P00672
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Phosphofructokinase-1 Synonym: Synonym not specified Accession: P00672
comment: ENTITY_REFERENCE_ID_DESC=Glycolysis.PROTEIN.GENERIC.Phosphofructokinase-1
member entity reference: ATP-dependent 6-phosphofructokinase, muscle type
member entity reference: ATP-dependent 6-phosphofructokinase
member entity reference: ATP-dependent 6-phosphofructokinase, liver type
member entity reference: ATP-dependent 6-phosphofructokinase 2

uniprot P0A9B2 91
type: UnificationXref
id: P0A9B2
db: uniprot

ncbitaxon 9606 13
type: UnificationXref
id: 9606
db: ncbitaxon

Gamma-enolase
type: ProteinReference
xref: PTHR11902:SF10
xref: uniprot P07323 123
organism: Rattus norvegicus

PANTHER Pathway P00024 1
type: UnificationXref
id: P00024
db: PANTHER Pathway

PTHR13697:SF4
type: RelationshipXref
id: PTHR13697:SF4
db: PANTHER Family
relationship type: By Homology

Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic
type: ProteinReference
xref: uniprot P25858 94
organism: Arabidopsis thaliana

uniprot Q9FC43 95
type: UnificationXref
id: Q9FC43
db: uniprot

uniprot F6Y855 97
type: UnificationXref
id: F6Y855
db: uniprot

Phosphoglyceromutase
type: ProteinReference
xref: P00680
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Glycolysis.PROTEIN.GENERIC.Phosphoglyceromutase
comment: ENTITY_REFERENCE_NOTES=Long Name: Phosphoglyceromutase Synonym: Synonym not specified Accession: P00680
member entity reference: Probable phosphoglycerate mutase 4
member entity reference: Phosphoglycerate mutase 3
member entity reference: Phosphoglycerate mutase
member entity reference: Phosphoglycerate mutase 1
member entity reference: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
member entity reference: Phosphoglycerate mutase 2
member entity reference: Bisphosphoglycerate mutase

uniprot P00942 51
type: UnificationXref
id: P00942
db: uniprot

STATE_TRANSITION_LEFT__Glucose_6_phosphate-RIGHT__Fructose_6_phosphate-_r6
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 213
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 212
left: Glucose 6-phosphate
interaction type: STATE_TRANSITION
right: Fructose 6-phosphate

uniprot P47858 49
type: UnificationXref
id: P47858
db: uniprot

Phosphotransferase
type: ProteinReference
xref: uniprot Q9W330 109
organism: Drosophila melanogaster

ncbitaxon 224308 26
type: UnificationXref
id: 224308
db: ncbitaxon

Phosphoglycerate kinase 1
type: ProteinReference
xref: uniprot Q3T0P6 29
xref: PTHR11406:SF14
organism: Bos taurus

STATE_TRANSITION_LEFT__1,_3_Bisphosphoglycerate-_2_ADP-RIGHT__2_ATP-_3_Phosphoglycerate-_r16
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r16 192
participant stoichiometry: PARTICIPANT STOICHIOMETRY r16 194
participant stoichiometry: PARTICIPANT STOICHIOMETRY r16 193
participant stoichiometry: PARTICIPANT STOICHIOMETRY r16 195
left: 1, 3-Bisphosphoglycerate
left: 2 ADP
interaction type: STATE_TRANSITION
right: 2 ATP
right: 3-Phosphoglycerate

uniprot Q3T0P6 29
type: UnificationXref
id: Q3T0P6
db: uniprot

Hexokinase
type: ProteinReference
xref: P00677
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Glycolysis.PROTEIN.GENERIC.Hexokinase
comment: ENTITY_REFERENCE_NOTES=Long Name: Hexokinase Synonym: Synonym not specified Accession: P00677
member entity reference: Uncharacterized protein
member entity reference: Putative hexokinase HKDC1
member entity reference: Hexokinase-2
member entity reference: Phosphotransferase
member entity reference: Hexokinase 2
member entity reference: Hexokinase-1
member entity reference: Hexokinase domain containing 1

uniprot P36623 167
type: UnificationXref
id: P36623
db: uniprot

uniprot A0A3Q1LMG1 134
type: UnificationXref
id: A0A3Q1LMG1
db: uniprot

uniprot F7E0Q7 140
type: UnificationXref
id: F7E0Q7
db: uniprot

uniprot Q9W330 109
type: UnificationXref
id: Q9W330
db: uniprot

uniprot B0BMH7 113
type: UnificationXref
id: B0BMH7
db: uniprot

Leishmania major
type: BioSource
xref: ncbitaxon 5664 147

uniprot P09104 124
type: UnificationXref
id: P09104
db: uniprot

Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic
type: ProteinReference
xref: uniprot P25856 93
organism: Arabidopsis thaliana

uniprot F6X1V9 115
type: UnificationXref
id: F6X1V9
db: uniprot

ENO2 protein
type: ProteinReference
xref: PTHR11902:SF10
xref: uniprot A6QR19 112
organism: Bos taurus

Uncharacterized protein
type: ProteinReference
xref: uniprot F7HAC6 98
organism: Macaca mulatta

Fructose-bisphosphate aldolase A
type: ProteinReference
xref: uniprot A5A6I5 135
xref: PTHR11627:SF1
organism: Pan troglodytes

Uncharacterized protein
type: ProteinReference
xref: uniprot F6Y855 97
organism: Macaca mulatta

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Glyceraldehyde_3_phosphate-RIGHT__Dihydroxyacetone_phosphate-_r13
controller: Triosephosphate isomerase

Phosphoglycerate mutase
type: ProteinReference
xref: uniprot P36623 167
xref: PTHR11931:SF0
organism: Schizosaccharomyces pombe

uniprot K7DD35 41
type: UnificationXref
id: K7DD35
db: uniprot

uniprot P60174 59
type: UnificationXref
id: P60174
db: uniprot

Phosphoglycerate kinase 1
type: ProteinReference
xref: uniprot P16617 16
xref: PTHR11406:SF14
organism: Rattus norvegicus

uniprot Q2TB90 107
type: UnificationXref
id: Q2TB90
db: uniprot

uniprot F6SYJ3 139
type: UnificationXref
id: F6SYJ3
db: uniprot

uniprot P17858 46
type: UnificationXref
id: P17858
db: uniprot

Probable phosphoglycerate mutase 4
type: ProteinReference
xref: uniprot Q8N0Y7 174
organism: Homo sapiens

uniprot P07486 89
type: UnificationXref
id: P07486
db: uniprot

PARTICIPANT STOICHIOMETRY r17 190
type: Stoichiometry
physical entity: 3-Phosphoglycerate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r17 191
type: Stoichiometry
physical entity: 2-Phosphoglycerate
stoichiometric coefficient: 1.0

Pyruvate kinase
type: ProteinReference
xref: PTHR11817:SF63
xref: uniprot Q8S7N6 80
organism: Oryza sativa

uniprot P08237 44
type: UnificationXref
id: P08237
db: uniprot

Phosphoglycerate kinase
type: ProteinReference
xref: uniprot F6SFZ4 6
xref: PTHR11406:SF14
organism: Macaca mulatta

ncbitaxon 272561 159
type: UnificationXref
id: 272561
db: ncbitaxon

uniprot P25696 129
type: UnificationXref
id: P25696
db: uniprot

uniprot Q8S7N6 80
type: UnificationXref
id: Q8S7N6
db: uniprot