RAF proto-oncogene serine/threonine-protein kinase
V-fos FBJ murine osteosarcoma viral oncogene homolog
SOS Ras/Rac guanine nucleotide exchange factor 1
Mitogen-activated protein kinase kinase 4
Non-specific serine/threonine protein kinase
Dual specificity mitogen-activated protein kinase kinase 1
Dual-specificity mitogen-activated protein kinase kinase 2
Cation-independent mannose-6-phosphate receptor
Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade
MODEL_NOTES=Panther Pathway: P00032 The insulin receptor (IR), insulin-like growth factor receptor (IGFR), and insulin-receptor-related receptor (IRR) form a subgroup of receptor tyrosine kinases that activate the mitogenic MAP kinase signalling cascade. The activated IR regulates cellular uptake and metabolism of fuels, while the activated IGFR promotes cell growth. Medline=11737239 Medline=11739335 Medline=11897402 Medline=12169433 Medline=12175645 Medline=12360255 PMID: 11737239 PMID: 11739335 PMID: 11897402 PMID: 12169433 PMID: 12175645 PMID: 12360255
Mitogen-activated protein kinase kinase 3
Mitogen-activated protein kinase kinase 4A
Probable serine/threonine-protein kinase DDB_G0271682
ENTITY_REFERENCE_NOTES=Long Name: ELK1, member of ETS oncogen family Synonym: ELK1,Oncogen ELK1 Accession: P00890
ENTITY_REFERENCE_ID_DESC=Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade.PROTEIN.GENERIC.ELK
Dual specificity mitogen-activated protein kinase kinase 3
Ras guanine nucleotide exchange factor R
Raf-1 proto-oncogene, serine/threonine kinase
ENTITY_REFERENCE_NOTES=Long Name: Raf Synonym: Raf oncogene Accession: P00893
ENTITY_REFERENCE_ID_DESC=Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade.PROTEIN.GENERIC.Raf
Transcription factor Elk; Uncharacterized protein
PAS domain-containing protein tyrosine kinase family protein
Putative ribosomal protein S6 kinase alpha-1
ENTITY_REFERENCE_ID_DESC=Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade.PROTEIN.GENERIC.Ras
ENTITY_REFERENCE_NOTES=Long Name: Ras Synonym: Synonym not specified Accession: P00886
Ras guanine nucleotide exchange factor B
Ras guanine nucleotide exchange factor A
Insulin receptor/Insulin like growth factor receptor/insulin related receptor
ENTITY_REFERENCE_ID_DESC=Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade.PROTEIN.RECEPTOR.INSR_br_IGF_minus_R_br_IRR
ENTITY_REFERENCE_NOTES=Long Name: Insulin receptor/Insulin like growth factor receptor/insulin related receptor Synonym: IGF-R,IGF-R1,IGF-R2,INSR,IRR,Insulin R,Insulin like growth factor receptor 1,Insulin like growth factor receptor 2 Accession: P00885
Mitogen-activated protein kinase (Fragment)
Website http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd
Insulin receptor substrate 3, isoform CRA_a (Fragment)
Dual specificity mitogen-activated protein kinase kinase 2
ENTITY_REFERENCE_NOTES=Long Name: Son of sevenless Synonym: SOS,SOS1 guanine nucleotide exchange factor Accession: P00883
ENTITY_REFERENCE_ID_DESC=Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade.PROTEIN.GENERIC.SOS
SOS Ras/Rho guanine nucleotide exchange factor 2
Mitogen-activated protein kinase kinase 1
ENTITY_REFERENCE_ID_DESC=Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade.PROTEIN.GENERIC.c_minus_fos
ENTITY_REFERENCE_NOTES=Long Name: c-fos Synonym: Synonym not specified Accession: P00884
Dual specificity mitogen-activated protein kinase kinase dSOR1
Fos proto-oncogene, AP-1 transcription factor subunit
ENTITY_REFERENCE_ID_DESC=Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade.PROTEIN.GENERIC.MEK
ENTITY_REFERENCE_NOTES=Long Name: Mitogen-activated protein kinase kinase Synonym: MAP kinase kinase,MAP/ERK kinase,MAPKK,Mitogen-activated ERK activating kinase Accession: P00891
ENTITY_REFERENCE_NOTES=Long Name: Insulin receptor substrate family Synonym: IRS Accession: P00887
ENTITY_REFERENCE_ID_DESC=Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade.PROTEIN.GENERIC.IRS_space_1_minus_4
Probable serine/threonine-protein kinase SIS8
ENTITY_REFERENCE_NOTES=Long Name: Mitogen-activated protein kinase Synonym: Extracellular signal-regulated kinase,MAP kinase,MAPK Accession: P00889
ENTITY_REFERENCE_ID_DESC=Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade.PROTEIN.GENERIC.ERK
ENTITY_REFERENCE_ID_DESC=Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade.PROTEIN.GENERIC.Grb2
ENTITY_REFERENCE_NOTES=Long Name: Growth factor receptor bound protein 2 Synonym: ASH protein,Abundant Src homology,Grb2 Accession: P00892
Chromosomal serine/threonine-protein kinase JIL-1
RAS p21 protein activator (GTPase activating protein) 1
ENTITY_REFERENCE_NOTES=Long Name: Insulin/Insulin like growth factor Synonym: IGF,IGF1,IGF2,Insulin like growth factor 1,Insulin like growth factor 2 Accession: P00882
ENTITY_REFERENCE_ID_DESC=Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade.PROTEIN.GENERIC.Insulin_br_IGF
FBJ murine osteosarcoma viral oncogene homolog
Mitogen-activated protein kinase kinase 2
ENTITY_REFERENCE_NOTES=Long Name: 90 kDa ribosomal protein S6 kinase Synonym: Synonym not specified Accession: P00888
ENTITY_REFERENCE_ID_DESC=Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade.PROTEIN.GENERIC.P90_space_RSK
Ras guanine nucleotide exchange factor Y