ENTITY_REFERENCE_NOTES=Long Name: Janus kinase 1 Synonym: Jak1 Accession: P00953
ENTITY_REFERENCE_ID_DESC=Interferon-gamma signaling pathway.PROTEIN.GENERIC.Jak1
Suppressor of variegation 2-10, isoform I
Cytokine-inducible SH2-containing protein
Complex (IFNGR1/IFNGR2/ Interferongamma)
Suppressor of cytokine signaling at 36E, isoform D
Tyrosine-protein phosphatase non-receptor type
ENTITY_REFERENCE_NOTES=Long Name: protein tyrosine phosphatase Synonym: PTP Accession: P00960
ENTITY_REFERENCE_ID_DESC=Interferon-gamma signaling pathway.PROTEIN.GENERIC.PTP
MODEL_NOTES=Panther Pathway: P00035 The interferon-gamma signaling pathway modulates the antiproliferative and antiviral properties of interferon-gamma. Signal transduction from the membrane to the nucleus is rapid and direct. The main signaling pathway involves the activation of STAT1 by the Jak family of tyrosine kinases at the cell membrane, followed by release, dimerization, and translocation of STAT1 to the nucleus, where they transcriptional induce expression of many gene products. Medline=11929133 Medline=14525967 PMID: 11929133 PMID: 14525967
Tyrosine-protein phosphatase non-receptor type ptp-2
Signal transducer and activator of transcription
Signal transducers and activaotrs of transcription 1
ENTITY_REFERENCE_NOTES=Long Name: Signal transducers and activaotrs of transcription 1 Synonym: STAT1 Accession: P00961
ENTITY_REFERENCE_ID_DESC=Interferon-gamma signaling pathway.PROTEIN.GENERIC.STAT1
Signal transducer and activator of transcription 1-alpha/beta
ENTITY_REFERENCE_ID_DESC=Interferon-gamma signaling pathway.PROTEIN.GENERIC.PIAS
ENTITY_REFERENCE_NOTES=Long Name: Protein inhibitors of activated STATs Synonym: PIAS Accession: P00958
Complex (IFNGR1/IFNGR2/ Interferongamma/STAT1/ Jak1/Jak2)
Signal transducer and activator of transcription 1
ENTITY_REFERENCE_ID_DESC=Interferon-gamma signaling pathway.PROTEIN.GENERIC.Serine kinase
ENTITY_REFERENCE_NOTES=Long Name: Serine kinase Synonym: Synonym not specified Accession: P00955
ENTITY_REFERENCE_NOTES=Long Name: Interferongamma Synonym: Synonym not specified Accession: P00954
ENTITY_REFERENCE_ID_DESC=Interferon-gamma signaling pathway.PROTEIN.GENERIC.Interferon_gamma_
Complex (IFNGR1/IFNGR2/ Interferongamma/Jak1/ Jak2)
Mitogen-activated protein kinase (Fragment)
Tyrosine-protein phosphatase non-receptor type 11
ENTITY_REFERENCE_ID_DESC=Interferon-gamma signaling pathway.PROTEIN.GENERIC.SOCS
ENTITY_REFERENCE_NOTES=Long Name: Suppressor of cytokine signaling Synonym: CIS,SOCS Accession: P00956
Tyrosine-protein phosphatase non-receptor type 6
Protein inhibitor of activated STAT 1 (Predicted)
ENTITY_REFERENCE_ID_DESC=Interferon-gamma signaling pathway.PROTEIN.RECEPTOR.IFNGR2
ENTITY_REFERENCE_NOTES=Long Name: IFNGR2 Synonym: Synonym not specified Accession: P00957
ENTITY_REFERENCE_ID_DESC=Interferon-gamma signaling pathway.PROTEIN.GENERIC.Jak2
ENTITY_REFERENCE_NOTES=Long Name: Janus kinase 2 Synonym: Jak2 Accession: P00952
ENTITY_REFERENCE_ID_DESC=Interferon-gamma signaling pathway.PROTEIN.RECEPTOR.IFNGR1
ENTITY_REFERENCE_NOTES=Long Name: IFNGR1 Synonym: Synonym not specified Accession: P00959
Cytokine inducible SH2 containing protein