CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__succinyl_CoA-_homoserine-RIGHT__CoA-_succinyl_homoserine-_r1
controller: Homoserine succinyltransferase

uniprot Q12525 26
type: UnificationXref
id: Q12525
db: uniprot

methionine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q8A531 6
type: UnificationXref
id: Q8A531
db: uniprot

Homocysteine S-methyltransferase
type: ProteinReference
xref: uniprot Q47690 28
organism: Escherichia coli

Anopheles gambiae
type: BioSource
xref: ncbitaxon 7165 36

uniprot Q9VJ32 54
type: UnificationXref
id: Q9VJ32
db: uniprot

Thermotoga maritima
type: BioSource
xref: ncbitaxon 243274 9

Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase
type: ProteinReference
xref: uniprot O06745 18
organism: Bacillus subtilis

Homocysteine S-methyltransferase YbgG
type: ProteinReference
xref: uniprot O31463 19
organism: Bacillus subtilis

Mus musculus
type: BioSource
xref: ncbitaxon 10090 11

uniprot P55217 64
type: UnificationXref
id: P55217
db: uniprot

uniprot A0A0P0VYR6 59
type: UnificationXref
id: A0A0P0VYR6
db: uniprot

ncbitaxon 39947 34
type: UnificationXref
id: 39947
db: ncbitaxon

Saccharomyces cerevisiae
type: BioSource
xref: ncbitaxon 559292 27

succinyl-CoA
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Synechocystis
type: BioSource
xref: ncbitaxon 1111708 32

uniprot H2R7Z7 16
type: UnificationXref
id: H2R7Z7
db: uniprot

Drosophila melanogaster
type: BioSource
xref: ncbitaxon 7227 53

uniprot Q4JIJ3 29
type: UnificationXref
id: Q4JIJ3
db: uniprot

uniprot Q94I39 71
type: UnificationXref
id: Q94I39
db: uniprot

ncbitaxon 9544 15
type: UnificationXref
id: 9544
db: ncbitaxon

uniprot Q8RI67 66
type: UnificationXref
id: Q8RI67
db: uniprot

Probable homocysteine S-methyltransferase MmuM (S-methylmethionine:homocysteine methyltransferase) (Cysteine methyltransferase)
type: ProteinReference
xref: uniprot O53185 22
organism: Mycobacterium tuberculosis

Homoserine O-acetyltransferase
type: ProteinReference
xref: uniprot Q8A531 6
organism: Bacteroides thetaiotaomicron

Cystathionine gamma-synthase 1, chloroplastic
type: ProteinReference
xref: uniprot P55217 64
organism: Arabidopsis thaliana

Homoserine O-acetyltransferase
type: ProteinReference
xref: uniprot Q9WZY3 8
organism: Thermotoga maritima

ncbitaxon 243230 50
type: UnificationXref
id: 243230
db: ncbitaxon

Homocysteine S-methyltransferase 1
type: ProteinReference
xref: uniprot Q9SDL7 51
organism: Arabidopsis thaliana

uniprot Q94I44 72
type: UnificationXref
id: Q94I44
db: uniprot

cysteine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot P38716 63
type: UnificationXref
id: P38716
db: uniprot

uniprot Q5ZBZ6 33
type: UnificationXref
id: Q5ZBZ6
db: uniprot

Methionine synthase
type: ProteinReference
xref: uniprot Q4JIJ3 29
organism: Bos taurus

Bacteroides thetaiotaomicron
type: BioSource
xref: ncbitaxon 226186 7

ncbitaxon 284812 61
type: UnificationXref
id: 284812
db: ncbitaxon

uniprot Q9X0Z7 74
type: UnificationXref
id: Q9X0Z7
db: uniprot

uniprot E2R716 12
type: UnificationXref
id: E2R716
db: uniprot

Methionine synthase
type: ProteinReference
xref: uniprot Q9I2Q2 46
organism: Pseudomonas aeruginosa

uniprot Q55786 31
type: UnificationXref
id: Q55786
db: uniprot

uniprot Q93IX6 70
type: UnificationXref
id: Q93IX6
db: uniprot

uniprot O53185 22
type: UnificationXref
id: O53185
db: uniprot

Schizosaccharomyces pombe
type: BioSource
xref: ncbitaxon 284812 61

uniprot Q8LAX0 39
type: UnificationXref
id: Q8LAX0
db: uniprot

PARTICIPANT STOICHIOMETRY r4 89
type: Stoichiometry
physical entity: homocysteine
stoichiometric coefficient: 1.0

uniprot Q9WYA5 55
type: UnificationXref
id: Q9WYA5
db: uniprot

Homoserine succinyltransferase
type: Protein
entity reference: Homoserine succinyltransferase
comment: SPECIES_TYPE=PROTEIN

uniprot P07623 2
type: UnificationXref
id: P07623
db: uniprot

Pan troglodytes
type: BioSource
xref: ncbitaxon 9598 17

ncbitaxon 226186 7
type: UnificationXref
id: 226186
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r4 90
type: Stoichiometry
physical entity: THF
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r4 91
type: Stoichiometry
physical entity: methionine
stoichiometric coefficient: 1.0

ncbitaxon 10116 57
type: UnificationXref
id: 10116
db: ncbitaxon

Methionine synthase
type: ProteinReference
xref: uniprot Q9Z2Q4 56
organism: Rattus norvegicus

CoA
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ncbitaxon 190304 42
type: UnificationXref
id: 190304
db: ncbitaxon

P03024
type: UnificationXref
id: P03024
db: PANTHER Pathway Component

P03023
type: UnificationXref
id: P03023
db: PANTHER Pathway Component

uniprot P43623 58
type: UnificationXref
id: P43623
db: uniprot

uniprot Q9Z2Q4 56
type: UnificationXref
id: Q9Z2Q4
db: uniprot

PARTICIPANT STOICHIOMETRY r1 86
type: Stoichiometry
physical entity: CoA
stoichiometric coefficient: 1.0

Cystathionine gamma-synthase
type: ProteinReference
xref: uniprot Q9X0Z7 74
organism: Thermotoga maritima

P03026
type: UnificationXref
id: P03026
db: PANTHER Pathway Component

PARTICIPANT STOICHIOMETRY r1 87
type: Stoichiometry
physical entity: succinyl-homoserine
stoichiometric coefficient: 1.0

P03025
type: UnificationXref
id: P03025
db: PANTHER Pathway Component

PARTICIPANT STOICHIOMETRY r4 88
type: Stoichiometry
physical entity: 5-CH3-THF
stoichiometric coefficient: 1.0

Deinococcus radiodurans
type: BioSource
xref: ncbitaxon 243230 50

homocysteine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q8CJP1 37
type: UnificationXref
id: Q8CJP1
db: uniprot

Methionine synthase
type: ProteinReference
xref: uniprot H2R7Z7 16
organism: Pan troglodytes

Homo sapiens
type: BioSource
xref: ncbitaxon 9606 44

ncbitaxon 100226 38
type: UnificationXref
id: 100226
db: ncbitaxon

H2O
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__cysteine-_succinyl_homoserine-RIGHT__cystathionine-_succinate-_r2
controller: O-Succinyl homoserine lyase

ncbitaxon 9598 17
type: UnificationXref
id: 9598
db: ncbitaxon

Uncharacterized trans-sulfuration enzyme C23A1.14c
type: ProteinReference
xref: uniprot O42851 60
organism: Schizosaccharomyces pombe

Arabidopsis thaliana
type: BioSource
xref: ncbitaxon 3702 40

ncbitaxon 10090 11
type: UnificationXref
id: 10090
db: ncbitaxon

ncbitaxon 9615 13
type: UnificationXref
id: 9615
db: ncbitaxon

STATE_TRANSITION_LEFT__cysteine-_succinyl_homoserine-RIGHT__cystathionine-_succinate-_r2
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 80
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 82
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 81
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 83
left: succinyl-homoserine
left: cysteine
interaction type: STATE_TRANSITION
right: succinate
right: cystathionine

uniprot O06745 18
type: UnificationXref
id: O06745
db: uniprot

PARTICIPANT STOICHIOMETRY r1 85
type: Stoichiometry
physical entity: homoserine
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r1 84
type: Stoichiometry
physical entity: succinyl-CoA
stoichiometric coefficient: 1.0

Putative transferase
type: ProteinReference
xref: uniprot Q8CJP1 37
organism: Streptomyces coelicolor

Homoserine succinyltransferase
type: ProteinReference
xref: P03023
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Methionine biosynthesis.PROTEIN.GENERIC.Homoserine_br_succinyltransferase
comment: ENTITY_REFERENCE_NOTES= Long Name: Homoserine succinyltransferase Synonym: Synonym not specified Accession: P03023
member entity reference: Homoserine O-succinyltransferase
member entity reference: Homoserine O-acetyltransferase

homoserine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Mycobacterium tuberculosis
type: BioSource
xref: ncbitaxon 83332 21

Homocysteine transmethylase
type: ProteinReference
xref: P03024
comment: ENTITY_REFERENCE_NOTES= Long Name: Homocysteine transmethylase Synonym: Synonym not specified Accession: P03024
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Methionine biosynthesis.PROTEIN.GENERIC.Homocysteine_br_transmethylase
member entity reference: Methionine synthase
member entity reference: 5-methyltetrahydrofolate--homocysteine methyltransferase
member entity reference: Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase
member entity reference: AGAP008537-PA (Fragment)
member entity reference: FI01821p
member entity reference: Homocysteine S-methyltransferase 3
member entity reference: Os01g0772900 protein
member entity reference: Homocysteine S-methyltransferase
member entity reference: Probable homocysteine S-methyltransferase MmuM (S-methylmethionine:homocysteine methyltransferase) (Cysteine methyltransferase)
member entity reference: Homocysteine S-methyltransferase 2
member entity reference: Putative transferase
member entity reference: Probable methionine synthase
member entity reference: Homocysteine S-methyltransferase 1
member entity reference: CG10623 protein
member entity reference: Homocysteine S-methyltransferase YbgG
member entity reference: 5-methyltetrahydrofolate S-homocysteine methyltransferase

Methionine biosynthesis
type: Pathway
pathway component: STATE_TRANSITION_LEFT__5_CH3_THF-_homocysteine-RIGHT__THF-_methionine-_r4
pathway component: STATE_TRANSITION_LEFT__succinyl_CoA-_homoserine-RIGHT__CoA-_succinyl_homoserine-_r1
pathway component: STATE_TRANSITION_LEFT__cystathionine-_H2O-RIGHT__homocysteine-_pyruvate-_NH3-_r3
pathway component: STATE_TRANSITION_LEFT__cysteine-_succinyl_homoserine-RIGHT__cystathionine-_succinate-_r2
xref: PANTHER Pathway P02753 1
comment: MODEL_NOTES= The biosynthesis of the sulfur containing amino acid methionine critical for protein biosynthesis. Website=www.biocyc.org/Ecoli/Pathways/ free text=Biochemistry (text) Voet and Voet

Escherichia coli
type: BioSource
xref: ncbitaxon 83333 3

ncbitaxon 7227 53
type: UnificationXref
id: 7227
db: ncbitaxon

uniprot Q59829 65
type: UnificationXref
id: Q59829
db: uniprot

uniprot Q9RVQ6 49
type: UnificationXref
id: Q9RVQ6
db: uniprot

succinate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

cystathionine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__cystathionine-_H2O-RIGHT__homocysteine-_pyruvate-_NH3-_r3
controller: Cystathionine lyase

Methionine synthase
type: ProteinReference
xref: uniprot Q9EWH3 45
organism: Streptomyces coelicolor

ncbitaxon 559292 27
type: UnificationXref
id: 559292
db: ncbitaxon

uniprot Q09582 24
type: UnificationXref
id: Q09582
db: uniprot

uniprot Q9VJ31 52
type: UnificationXref
id: Q9VJ31
db: uniprot

ncbitaxon 224308 5
type: UnificationXref
id: 224308
db: ncbitaxon

Homocysteine S-methyltransferase 3
type: ProteinReference
xref: uniprot Q8LAX0 39
organism: Arabidopsis thaliana

uniprot Q7PNI0 35
type: UnificationXref
id: Q7PNI0
db: uniprot

Methionine synthase
type: ProteinReference
xref: uniprot Q55786 31
organism: Synechocystis

Bacillus subtilis
type: BioSource
xref: ncbitaxon 224308 5

Fusobacterium nucleatum
type: BioSource
xref: ncbitaxon 190304 42

Bos taurus
type: BioSource
xref: ncbitaxon 9913 30

uniprot Q9I2Q2 46
type: UnificationXref
id: Q9I2Q2
db: uniprot

Macaca mulatta
type: BioSource
xref: ncbitaxon 9544 15

NH3
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Homoserine O-acetyltransferase
type: ProteinReference
xref: uniprot P54167 4
organism: Bacillus subtilis

Methionine synthase
type: ProteinReference
xref: uniprot G7MFM9 14
organism: Macaca mulatta

ncbitaxon 243274 9
type: UnificationXref
id: 243274
db: ncbitaxon

O-Succinyl homoserine lyase
type: ProteinReference
xref: P03026
comment: ENTITY_REFERENCE_NOTES= Long Name: O-Succinyl homoserine lyase Synonym: Synonym not specified Accession: P03026
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Methionine biosynthesis.PROTEIN.GENERIC.O-Succinyl homoserine_br_lyase
member entity reference: Probable cystathionine gamma-synthase
member entity reference: Os03g0376100 protein (Fragment)
member entity reference: Uncharacterized trans-sulfuration enzyme YHR112C
member entity reference: Cys/Met metabolism PLP-dependent enzyme family protein, expressed
member entity reference: Cystathionine gamma-synthase
member entity reference: Putative cystathionine gamma-lyase
member entity reference: Probable cystathionine gamma-synthase 2
member entity reference: Cystathionine gamma-synthase 1, chloroplastic
member entity reference: Cystathionine beta-lyase
member entity reference: Uncharacterized trans-sulfuration enzyme C23A1.14c
member entity reference: Putative cystathionine gamma-synthase
member entity reference: Cys/Met metabolism PLP-dependent enzyme family protein

5-methyltetrahydrofolate--homocysteine methyltransferase
type: ProteinReference
xref: uniprot Q8RGW4 41
organism: Fusobacterium nucleatum

uniprot P54167 4
type: UnificationXref
id: P54167
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__5_CH3_THF-_homocysteine-RIGHT__THF-_methionine-_r4
controller: Homocysteine transmethylase

ncbitaxon 1111708 32
type: UnificationXref
id: 1111708
db: ncbitaxon

Os03g0376100 protein (Fragment)
type: ProteinReference
xref: uniprot A0A0P0VYR6 59
organism: Oryza sativa

Methionine synthase
type: ProteinReference
xref: uniprot E2R716 12
organism: Canis lupus familiaris

CG10623 protein
type: ProteinReference
xref: uniprot Q9VJ31 52
organism: Drosophila melanogaster

Methionine synthase
type: ProteinReference
xref: uniprot A6H5Y3 10
organism: Mus musculus

Homocysteine transmethylase
type: Protein
entity reference: Homocysteine transmethylase
comment: SPECIES_TYPE=PROTEIN

O-Succinyl homoserine lyase
type: Protein
entity reference: O-Succinyl homoserine lyase
comment: SPECIES_TYPE=PROTEIN

FI01821p
type: ProteinReference
xref: uniprot Q9VJ32 54
organism: Drosophila melanogaster

uniprot P13009 23
type: UnificationXref
id: P13009
db: uniprot

Rattus norvegicus
type: BioSource
xref: ncbitaxon 10116 57

uniprot O31463 19
type: UnificationXref
id: O31463
db: uniprot

uniprot Q9C876 73
type: UnificationXref
id: Q9C876
db: uniprot

Canis lupus familiaris
type: BioSource
xref: ncbitaxon 9615 13

uniprot Q99707 43
type: UnificationXref
id: Q99707
db: uniprot

uniprot Q8ZV75 68
type: UnificationXref
id: Q8ZV75
db: uniprot

Uncharacterized trans-sulfuration enzyme YHR112C
type: ProteinReference
xref: uniprot P38716 63
organism: Saccharomyces cerevisiae

Pyrobaculum aerophilum
type: BioSource
xref: ncbitaxon 178306 69

5-methyltetrahydrofolate S-homocysteine methyltransferase
type: ProteinReference
xref: uniprot Q9WYA5 55
organism: Thermotoga maritima

Putative cystathionine gamma-lyase
type: ProteinReference
xref: uniprot Q59829 65
organism: Streptomyces coelicolor

Putative cystathionine gamma-synthase
type: ProteinReference
xref: uniprot Q93IX6 70
organism: Streptomyces coelicolor

PANTHER Pathway P02753 1
type: UnificationXref
id: P02753
db: PANTHER Pathway

Cystathionine lyase
type: Protein
entity reference: Cystathionine lyase
comment: SPECIES_TYPE=PROTEIN

ncbitaxon 83332 21
type: UnificationXref
id: 83332
db: ncbitaxon

Cystathionine beta-lyase
type: ProteinReference
xref: uniprot Q8RI67 66
organism: Fusobacterium nucleatum

Cystathionine gamma-synthase
type: ProteinReference
xref: uniprot Q8RI68 67
organism: Fusobacterium nucleatum

Streptomyces coelicolor
type: BioSource
xref: ncbitaxon 100226 38

Methionine synthase
type: ProteinReference
xref: uniprot O33259 20
organism: Mycobacterium tuberculosis

Probable cystathionine gamma-synthase 2
type: ProteinReference
xref: uniprot Q9C876 73
organism: Arabidopsis thaliana

ncbitaxon 9606 44
type: UnificationXref
id: 9606
db: ncbitaxon

uniprot Q47690 28
type: UnificationXref
id: Q47690
db: uniprot

Cys/Met metabolism PLP-dependent enzyme family protein
type: ProteinReference
xref: uniprot Q94I44 72
organism: Oryza sativa

THF
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

STATE_TRANSITION_LEFT__cystathionine-_H2O-RIGHT__homocysteine-_pyruvate-_NH3-_r3
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 77
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 79
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 78
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 76
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 75
left: H2O
left: cystathionine
interaction type: STATE_TRANSITION
right: NH3
right: pyruvate
right: homocysteine

uniprot O42851 60
type: UnificationXref
id: O42851
db: uniprot

ncbitaxon 6239 25
type: UnificationXref
id: 6239
db: ncbitaxon

STATE_TRANSITION_LEFT__5_CH3_THF-_homocysteine-RIGHT__THF-_methionine-_r4
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 88
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 90
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 91
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 89
left: 5-CH3-THF
left: homocysteine
interaction type: STATE_TRANSITION
right: THF
right: methionine

uniprot Q8RGW4 41
type: UnificationXref
id: Q8RGW4
db: uniprot

STATE_TRANSITION
type: InteractionVocabulary

STATE_TRANSITION
type: RelationshipTypeVocabulary

uniprot G7MFM9 14
type: UnificationXref
id: G7MFM9
db: uniprot

uniprot Q9EWH3 45
type: UnificationXref
id: Q9EWH3
db: uniprot

ncbitaxon 7165 36
type: UnificationXref
id: 7165
db: ncbitaxon

uniprot Q9WZY3 8
type: UnificationXref
id: Q9WZY3
db: uniprot

Homocysteine S-methyltransferase 1
type: ProteinReference
xref: uniprot Q12525 26
organism: Saccharomyces cerevisiae

Methionine synthase
type: ProteinReference
xref: uniprot Q9RVQ6 49
organism: Deinococcus radiodurans

Probable cystathionine gamma-synthase
type: ProteinReference
xref: uniprot O74314 62
organism: Schizosaccharomyces pombe

uniprot A6H5Y3 10
type: UnificationXref
id: A6H5Y3
db: uniprot

ncbitaxon 178306 69
type: UnificationXref
id: 178306
db: ncbitaxon

Cys/Met metabolism PLP-dependent enzyme family protein, expressed
type: ProteinReference
xref: uniprot Q94I39 71
organism: Oryza sativa

Putative cystathionine beta-lyase
type: ProteinReference
xref: uniprot P43623 58
organism: Saccharomyces cerevisiae

pyruvate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Os01g0772900 protein
type: ProteinReference
xref: uniprot Q5ZBZ6 33
organism: Oryza sativa

Cystathionine lyase
type: ProteinReference
xref: P03025
comment: ENTITY_REFERENCE_ID_DESC=Methionine biosynthesis.PROTEIN.GENERIC.Cystathionine_br_lyase
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: Cystathionine lyase Synonym: Synonym not specified Accession: P03025
member entity reference: Putative cystathionine beta-lyase

Cystathionine gamma-synthase
type: ProteinReference
xref: uniprot Q8ZV75 68
organism: Pyrobaculum aerophilum

ncbitaxon 9913 30
type: UnificationXref
id: 9913
db: ncbitaxon

Probable methionine synthase
type: ProteinReference
xref: uniprot Q09582 24
organism: Caenorhabditis elegans

Homocysteine S-methyltransferase 2
type: ProteinReference
xref: uniprot Q9M1W4 48
organism: Arabidopsis thaliana

Caenorhabditis elegans
type: BioSource
xref: ncbitaxon 6239 25

PARTICIPANT STOICHIOMETRY r3 77
type: Stoichiometry
physical entity: homocysteine
stoichiometric coefficient: 1.0

ncbitaxon 83333 3
type: UnificationXref
id: 83333
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r3 78
type: Stoichiometry
physical entity: pyruvate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r3 79
type: Stoichiometry
physical entity: NH3
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r2 82
type: Stoichiometry
physical entity: cystathionine
stoichiometric coefficient: 1.0

succinyl-homoserine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r2 81
type: Stoichiometry
physical entity: succinyl-homoserine
stoichiometric coefficient: 1.0

5-CH3-THF
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r2 80
type: Stoichiometry
physical entity: cysteine
stoichiometric coefficient: 1.0

Methionine synthase
type: ProteinReference
xref: uniprot P13009 23
organism: Escherichia coli

PARTICIPANT STOICHIOMETRY r2 83
type: Stoichiometry
physical entity: succinate
stoichiometric coefficient: 1.0

ncbitaxon 3702 40
type: UnificationXref
id: 3702
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r3 76
type: Stoichiometry
physical entity: H2O
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r3 75
type: Stoichiometry
physical entity: cystathionine
stoichiometric coefficient: 1.0

STATE_TRANSITION_LEFT__succinyl_CoA-_homoserine-RIGHT__CoA-_succinyl_homoserine-_r1
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 84
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 85
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 86
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 87
left: homoserine
left: succinyl-CoA
interaction type: STATE_TRANSITION
right: succinyl-homoserine
right: CoA

AGAP008537-PA (Fragment)
type: ProteinReference
xref: uniprot Q7PNI0 35
organism: Anopheles gambiae

ncbitaxon 208964 47
type: UnificationXref
id: 208964
db: ncbitaxon

Methionine synthase
type: ProteinReference
xref: uniprot Q99707 43
organism: Homo sapiens

Oryza sativa
type: BioSource
xref: ncbitaxon 39947 34

Homoserine O-succinyltransferase
type: ProteinReference
xref: uniprot P07623 2
organism: Escherichia coli

uniprot O74314 62
type: UnificationXref
id: O74314
db: uniprot

uniprot O33259 20
type: UnificationXref
id: O33259
db: uniprot

Pseudomonas aeruginosa
type: BioSource
xref: ncbitaxon 208964 47

uniprot Q9M1W4 48
type: UnificationXref
id: Q9M1W4
db: uniprot

uniprot Q9SDL7 51
type: UnificationXref
id: Q9SDL7
db: uniprot

uniprot Q8RI68 67
type: UnificationXref
id: Q8RI68
db: uniprot