ENTITY_REFERENCE_NOTES= Long Name: acetylcholinesterase Synonym: ACHE,AChE Accession: P01080
ENTITY_REFERENCE_ID_DESC=Muscarinic acetylcholine receptor 2 and 4 signaling pathway.PROTEIN.GENERIC.AChE
Guanine nucleotide-binding protein subunit gamma
cAMP-dependent protein kinase regulatory subunit
Guanine nucleotide-binding protein G(t) subunit alpha-1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
cAMP-dependent protein kinase catalytic subunit alpha
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Guanine nucleotide-binding protein subunit beta-5
Protein kinase cAMP-activated catalytic subunit beta
ENTITY_REFERENCE_NOTES= Long Name: choline acetyltransferase Synonym: CAT,CHAT Accession: P01076
ENTITY_REFERENCE_ID_DESC=Muscarinic acetylcholine receptor 2 and 4 signaling pathway.PROTEIN.GENERIC.CAT
Guanine nucleotide-binding protein (G protein), alpha-inhibiting activity polypeptide 2
Potassium channel, inwardly rectifying subfamily J, member 3
Protein serine/threonine kinase, putative
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
Potassium voltage-gated channel subfamily J member 6
Putative synaptobrevin homologue SNC1/2 (Eurofung)
Guanine nucleotide binding protein, beta 3
G protein-activated inward rectifier potassium channel 1
Guanine nucleotide-binding protein G(O) subunit alpha 1
cAMP-dependent protein kinase catalytic subunit beta
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
Vesicle-associated membrane protein 8 (Endobrevin)
Muscarinic acetylcholine receptor M2 (Fragment)
Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue-specific extinguisher 1) b
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
MODEL_NOTES=Panther Pathway: P00043 Muscarinic Acetylcholine Receptor 2, 4 Pathway: Muscarinic ACh receptors are negatively coupled to PKA and intracellular cAMP signaling. These receptors are found in the brain controlling attention (eg. reduction of cholinergic fibers in elderly and trisomy 21 patients leads to Alzheimer's disease) and peripheral nervous system controlling parasympathetic responses (eg. release of acetylcholine from the vagus nerve reduces heart rate and blood pressure). These receptors are important existing drug targets for heart disease, hypertension, bronchial asthma, anesthesia, Alzheimer's disease, and one of the main mechanisms for dilated cardiomyopathy is likely to be autoimmune (against m2) mediated myocardial damage. Website=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12667888 Website=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9711178 Website=http://www.ptd.neu.edu/neuroanatomy/cyberclass/pharmacology/acetylcholine.htm Website=http://www.unifr.ch/biochem/DREYER/Neurotransmitters/acetylcholine.htm PMID: 12667888 PMID: 9711178
cAMP-dependent protein kinase catalytic subunit
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b
Protein kinase, cAMP-dependent, catalytic, beta a
Potassium voltage-gated channel subfamily J member 3
Protein kinase cAMP-dependent type II regulatory subunit alpha
Protein kinase cAMP-dependent type I regulatory subunit alpha
Guanine nucleotide-binding protein G(k) subunit alpha
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
Guanine nucleotide-binding protein G(i) subunit alpha-1
Guanine nucleotide-binding protein G(t) subunit alpha-2
cAMP-dependent protein kinase type I-beta regulatory subunit
cAMP-dependent protein kinase type I-alpha regulatory subunit
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
cAMP-dependent protein kinase type II-beta regulatory subunit
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
Guanine nucleotide-binding protein subunit beta-2
Guanine nucleotide-binding protein G(i) subunit alpha-2
Guanine nucleotide-binding protein G(o) subunit alpha
Guanine nucleotide-binding protein subunit beta-1
G protein-activated inward rectifier potassium channel 2
cAMP-dependent protein kinase type II-alpha regulatory subunit
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a
Guanine nucleotide-binding protein G(K) subunit alpha
Guanine nucleotide-binding protein subunit beta-4
Guanine nucleotide-binding protein subunit beta
Guanine nucleotide-binding protein subunit beta-5b
Protein kinase cAMP-dependent type II regulatory subunit beta
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
ENTITY_REFERENCE_NOTES= Long Name: high affinity choline transporter Synonym: cht1 Accession: P01084
ENTITY_REFERENCE_ID_DESC=Muscarinic acetylcholine receptor 2 and 4 signaling pathway.PROTEIN.GENERIC.CHT1
Solute carrier family 5 (Choline transporter), member 7
Potassium voltage-gated channel subfamily J member 9
G protein-activated inward rectifier potassium channel 3
Guanine nucleotide binding protein (G protein), beta polypeptide 3, like
Putative SNAP25 homologous protein SNAP30
Guanine nucleotide-binding protein (G protein), alpha-inhibiting activity polypeptide 1
Muscarinic acetylcholine receptor 2 and 4
ENTITY_REFERENCE_ID_DESC=Muscarinic acetylcholine receptor 2 and 4 signaling pathway.PROTEIN.RECEPTOR.mAChR2/4
cAMP-dependent protein kinase catalytic subunit 3
Guanine nucleotide-binding protein (G protein), beta 5
cAMP-dependent protein kinase type I regulatory subunit
Protein kinase, cAMP-dependent, catalytic, beta
Protein kinase A catalytic subunit isoform 1
ENTITY_REFERENCE_ID_DESC=Muscarinic acetylcholine receptor 2 and 4 signaling pathway.PROTEIN.GENERIC.VAChT
ENTITY_REFERENCE_NOTES= Long Name: vesicular acetylcholine transporter Synonym: CG32848,VAChT Accession: P01078
Guanine nucleotide-binding protein (G protein), alpha-inhibiting activity polypeptide 2b
Sodium- and chloride-dependent creatine transporter 1
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
G protein-coupled inwardly rectifying potassium channel
ENTITY_REFERENCE_NOTES= Long Name: G protein-coupled inwardly rectifying potassium channel Synonym: GIRK Accession: P01083
ENTITY_REFERENCE_ID_DESC=Muscarinic acetylcholine receptor 2 and 4 signaling pathway.PROTEIN.ION_CHANNEL.GIRK
cAMP-dependent protein kinase catalytic subunit PRKX
cAMP-dependent protein kinase, catalytic subunit-like
Protein kinase, cAMP-dependent, regulatory, type II, alpha, B
Guanine nucleotide-binding protein G(O) subunit alpha isoform a
Guanine nucleotide-binding protein beta subunit
Protein kinase, cAMP-dependent, regulatory, type I, beta
ENTITY_REFERENCE_ID_DESC=Muscarinic acetylcholine receptor 2 and 4 signaling pathway.PROTEIN.GENERIC.PKA
ENTITY_REFERENCE_NOTES= Long Name: Protein Kinase A Synonym: PKA Accession: P01075
cAMP-dependent protein kinase catalytic subunit 1
Guanine nucleotide-binding protein subunit gamma-1
Guanine nucleotide binding protein, beta subunit
cAMP-dependent protein kinase type II regulatory subunit
cAMP-dependent protein kinase catalytic subunit gamma
Sodium-dependent acetylcholine transporter
Protein kinase cAMP-activated catalytic subunit alpha
ENTITY_REFERENCE_ID_DESC=Muscarinic acetylcholine receptor 2 and 4 signaling pathway.PROTEIN.GENERIC.AC
ENTITY_REFERENCE_NOTES= Long Name: Adenylate Cyclase Synonym: AC Accession: P01082
Potassium voltage-gated channel subfamily J member 5
heart muscle or neuron cytosol, or nerve terminal
N-ethylmaleimide-sensitive factor attachment protein receptor
ENTITY_REFERENCE_ID_DESC=Muscarinic acetylcholine receptor 2 and 4 signaling pathway.PROTEIN.GENERIC.SNARE COMPLEX
ENTITY_REFERENCE_NOTES= Long Name: N-ethylmaleimide-sensitive factor attachment protein receptor Synonym: SNARE Accession: P01079
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
G protein-activated inward rectifier potassium channel 4
Guanine nucleotide-binding protein (G protein), alpha-inhibiting activity polypeptide a
cAMP-dependent protein kinase catalytic subunit alpha isoform 1
cAMP/cGMP-dependent 3',5'-cAMP/cGMP phosphodiesterase B
ENTITY_REFERENCE_ID_DESC=Muscarinic acetylcholine receptor 2 and 4 signaling pathway.PROTEIN.GENERIC.G-Protein
Protein kinase A catalytic subunit isoform 2
Uncharacterized MFS-type transporter C18.02
cGMP-dependent 3',5'-cGMP phosphodiesterase A
cAMP-dependent protein kinase catalytic subunit TPK2
cAMP-dependent protein kinase catalytic subunit beta isoform 1