uniprot P31470 88
type: UnificationXref
id: P31470
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__N_acetyl_D_mannosamine_6_phosphate-RIGHT__N_acetyl_D_glucos_amine_6_phosphate-_r3
controller: N-acetylmannosamine-6-phospate epimerase

uniprot Q9HT00 140
type: UnificationXref
id: Q9HT00
db: uniprot

uniprot F6R0B7 103
type: UnificationXref
id: F6R0B7
db: uniprot

uniprot F7FMF5 108
type: UnificationXref
id: F7FMF5
db: uniprot

uniprot P34480 16
type: UnificationXref
id: P34480
db: uniprot

Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
type: ProteinReference
xref: uniprot Q06210 125
organism: Homo sapiens

Gloeobacter violaceus
type: BioSource
xref: ncbitaxon 251221 43

ncbitaxon 208964 26
type: UnificationXref
id: 208964
db: ncbitaxon

CoA
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Glucosamine-6-phosphate isomerase
type: ProteinReference
xref: uniprot A0A1D5R8R9 66
organism: Macaca mulatta

STATE_TRANSITION_LEFT__H2O-_D_glucosamine_6_phosphate-RIGHT__fructose_6_phosphate-_NH3-_r6
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 184
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 182
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 185
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 183
left: H2O
left: D-glucosamine-6-phosphate
interaction type: STATE_TRANSITION
right: NH3
right: fructose-6-phosphate

uniprot P53704 120
type: UnificationXref
id: P53704
db: uniprot

Bifunctional protein GlmU
type: ProteinReference
xref: uniprot Q9RW61 50
organism: Deinococcus radiodurans

Probable aminotransferase
type: ProteinReference
xref: uniprot Q9HXN6 143
organism: Pseudomonas aeruginosa

Probable N-acetylglucosamine-6-phosphate deacetylase
type: ProteinReference
xref: uniprot Q9HXN7 25
organism: Pseudomonas aeruginosa

Giardia intestinalis
type: BioSource
xref: ncbitaxon 184922 75

ncbitaxon 7227 32
type: UnificationXref
id: 7227
db: ncbitaxon

Bifunctional protein GlmU
type: ProteinReference
xref: uniprot Q7NNG8 42
organism: Gloeobacter violaceus

Mus musculus
type: BioSource
xref: ncbitaxon 10090 23

ncbitaxon 224324 40
type: UnificationXref
id: 224324
db: ncbitaxon

uniprot F6R5T8 77
type: UnificationXref
id: F6R5T8
db: uniprot

GH12731p
type: ProteinReference
xref: uniprot Q9VAW3 149
organism: Drosophila melanogaster

Saccharomyces cerevisiae
type: BioSource
xref: ncbitaxon 559292 99

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot Q8ZTZ0 138
organism: Pyrobaculum aerophilum

Drosophila melanogaster
type: BioSource
xref: ncbitaxon 7227 32

uniprot P14192 41
type: UnificationXref
id: P14192
db: uniprot

Glutamine-Fructose 6-phosphate AminoTransferase homolog
type: ProteinReference
xref: uniprot Q19130 128
organism: Caenorhabditis elegans

uniprot A0A1D5QL39 52
type: UnificationXref
id: A0A1D5QL39
db: uniprot

N-acetyl-D-glucos-amine-6-phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A1D5QL39 52
organism: Macaca mulatta

N-acetylglucosamine-6-phosphate deacetylase
type: ProteinReference
xref: uniprot Q5BJY6 18
organism: Rattus norvegicus

N-acetylneuraminate pyruvate lyase
type: ProteinReference
xref: uniprot H2Q0Q9 57
organism: Pan troglodytes

uniprot Q9KXV7 27
type: UnificationXref
id: Q9KXV7
db: uniprot

Bifunctional protein GlmU
type: ProteinReference
xref: uniprot O66863 39
organism: Aquifex aeolicus

uniprot O94808 115
type: UnificationXref
id: O94808
db: uniprot

Glutamine-fructose-6-phosphate transaminase 2
type: ProteinReference
xref: uniprot Q9LIP9 145
organism: Arabidopsis thaliana

Bifunctional protein GlmU
type: ProteinReference
xref: uniprot Q9X1W4 51
organism: Thermotoga maritima

Glucosamine-6-phosphate isomerase
type: ProteinReference
xref: uniprot H2QPE3 83
organism: Pan troglodytes

uniprot Q9VR81 31
type: UnificationXref
id: Q9VR81
db: uniprot

PARTICIPANT STOICHIOMETRY r5 155
type: Stoichiometry
physical entity: glutamine
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r5 156
type: Stoichiometry
physical entity: D-glucosamine-6-phosphate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r5 157
type: Stoichiometry
physical entity: glutamate
stoichiometric coefficient: 1.0

Glucosamine-6-phosphate deaminase
type: ProteinReference
xref: uniprot Q9K487 94
organism: Streptomyces coelicolor

PARTICIPANT STOICHIOMETRY r5 158
type: Stoichiometry
physical entity: Fructose-6-phosphate
stoichiometric coefficient: 1.0

uniprot Q8RDN7 38
type: UnificationXref
id: Q8RDN7
db: uniprot

N-acetylglucosamine-6-phosphate deacetylase
type: ProteinReference
xref: uniprot P0AF18 14
organism: Escherichia coli

uniprot Q9HXN7 25
type: UnificationXref
id: Q9HXN7
db: uniprot

acetate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q19699 129
type: UnificationXref
id: Q19699
db: uniprot

uniprot Q9Z2Z9 152
type: UnificationXref
id: Q9Z2Z9
db: uniprot

uniprot A4FV08 68
type: UnificationXref
id: A4FV08
db: uniprot

uniprot Q9RZ88 29
type: UnificationXref
id: Q9RZ88
db: uniprot

uniprot E2RU05 76
type: UnificationXref
id: E2RU05
db: uniprot

Pan troglodytes
type: BioSource
xref: ncbitaxon 9598 58

N-acetylglucosamine-6-phosphate deacetylase
type: ProteinReference
xref: uniprot P34480 16
organism: Caenorhabditis elegans

Xenopus tropicalis
type: BioSource
xref: ncbitaxon 8364 81

Glucosamine-6-phosphate isomerase
type: ProteinReference
xref: uniprot F7H603 82
organism: Macaca mulatta

PARTICIPANT STOICHIOMETRY r7 181
type: Stoichiometry
physical entity: D-glucosamine-1-phosphate
stoichiometric coefficient: 1.0

Bifunctional protein GlmU
type: ProteinReference
xref: uniprot Q8RHM3 49
organism: Fusobacterium nucleatum

uniprot Q4KMC4 130
type: UnificationXref
id: Q4KMC4
db: uniprot

PARTICIPANT STOICHIOMETRY r7 180
type: Stoichiometry
physical entity: D-glucosamine-6-phosphate
stoichiometric coefficient: 1.0

Uncharacterized protein
type: ProteinReference
xref: uniprot F6R5T8 77
organism: Monodelphis domestica

ncbitaxon 3702 146
type: UnificationXref
id: 3702
db: ncbitaxon

Glucosamine-6-phosphate deaminase
type: Protein
entity reference: Glucosamine-6-phosphate deaminase
comment: SPECIES_TYPE=PROTEIN

Uncharacterized protein
type: ProteinReference
xref: uniprot F7FMF5 108
organism: Monodelphis domestica

STATE_TRANSITION_LEFT__glutamine-_D_glucosamine_6_phosphate-RIGHT__glutamate-_Fructose_6_phosphate-_r5
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 158
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 155
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 156
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 157
left: D-glucosamine-6-phosphate
left: glutamine
interaction type: STATE_TRANSITION
right: glutamate
right: Fructose-6-phosphate

ncbitaxon 243230 30
type: UnificationXref
id: 243230
db: ncbitaxon

uniprot Q9HXN6 143
type: UnificationXref
id: Q9HXN6
db: uniprot

ncbitaxon 6239 17
type: UnificationXref
id: 6239
db: ncbitaxon

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot O66648 112
organism: Aquifex aeolicus

N-acetylneuraminate pyruvate lyase
type: ProteinReference
xref: uniprot E2RAE9 55
organism: Canis lupus familiaris

uniprot O88958 87
type: UnificationXref
id: O88958
db: uniprot

N-acetylglucosamine-6-phosphate deacetylase
type: ProteinReference
xref: uniprot A0A1D8PQG3 4
organism: Candida albicans

PARTICIPANT STOICHIOMETRY r6 182
type: Stoichiometry
physical entity: H2O
stoichiometric coefficient: 1.0

D-glucosamine-1-phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot E2RH59 73
type: UnificationXref
id: E2RH59
db: uniprot

ncbitaxon 7165 21
type: UnificationXref
id: 7165
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r6 185
type: Stoichiometry
physical entity: NH3
stoichiometric coefficient: 1.0

uniprot Q06210 125
type: UnificationXref
id: Q06210
db: uniprot

PARTICIPANT STOICHIOMETRY r6 184
type: Stoichiometry
physical entity: fructose-6-phosphate
stoichiometric coefficient: 1.0

Uncharacterized protein YMR085W
type: ProteinReference
xref: uniprot P0CF18 116
organism: Saccharomyces cerevisiae

PARTICIPANT STOICHIOMETRY r6 183
type: Stoichiometry
physical entity: D-glucosamine-6-phosphate
stoichiometric coefficient: 1.0

Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2
type: ProteinReference
xref: uniprot Q4KMC4 130
organism: Rattus norvegicus

uniprot Q8RHM3 49
type: UnificationXref
id: Q8RHM3
db: uniprot

Glucosamine--fructose-6-phosphate aminotransferase-related protein
type: ProteinReference
xref: uniprot Q9RYZ9 148
organism: Deinococcus radiodurans

uniprot Q9VAW3 149
type: UnificationXref
id: Q9VAW3
db: uniprot

uniprot Q8R6A7 2
type: UnificationXref
id: Q8R6A7
db: uniprot

N-acetylglucosamine-6-phosphate deacetylase
type: ProteinReference
xref: uniprot Q9VR81 31
organism: Drosophila melanogaster

Glutamine--fructose-6-phosphate transaminase 1
type: ProteinReference
xref: uniprot F7CBS8 107
organism: Monodelphis domestica

N-acetylmannosamine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r3 164
type: Stoichiometry
physical entity: N-acetyl-D-glucos-amine-6-phosphate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r3 163
type: Stoichiometry
physical entity: N-acetyl-D-mannosamine-6-phosphate
stoichiometric coefficient: 1.0

STATE_TRANSITION_LEFT__N_acetylglucosamine_1_phosphate-_UTP-RIGHT__UDP_N_acetyl_D_glucosamine-_PPi-_r9
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r9 172
participant stoichiometry: PARTICIPANT STOICHIOMETRY r9 174
participant stoichiometry: PARTICIPANT STOICHIOMETRY r9 173
participant stoichiometry: PARTICIPANT STOICHIOMETRY r9 175
left: N-acetylglucosamine-1-phosphate
left: UTP
interaction type: STATE_TRANSITION
right: PPi
right: UDP-N-acetyl-D-glucosamine

uniprot P9WN49 124
type: UnificationXref
id: P9WN49
db: uniprot

N-acetylmannosamine kinase
type: ProteinReference
xref: P03038
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=N-acetylglucosamine metabolism.PROTEIN.GENERIC.N-acetylmannosamine_br_kinase
comment: ENTITY_REFERENCE_NOTES= Long Name: N-acetylmannosamine kinase Synonym: Synonym not specified Accession: P03038
member entity reference: N-acetylmannosamine kinase

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot Q9HT25 142
organism: Pseudomonas aeruginosa

PARTICIPANT STOICHIOMETRY r9 172
type: Stoichiometry
physical entity: N-acetylglucosamine-1-phosphate
stoichiometric coefficient: 1.0

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot Q58815 131
organism: Methanocaldococcus jannaschii

uniprot O34450 10
type: UnificationXref
id: O34450
db: uniprot

Glucosamine-6-phosphate isomerase
type: ProteinReference
xref: uniprot E2RTN3 74
organism: Giardia intestinalis

Glucosamine-6-phosphate deaminase
type: ProteinReference
xref: P03041
comment: ENTITY_REFERENCE_ID_DESC=N-acetylglucosamine metabolism.PROTEIN.GENERIC.Glucosamine-6-phosphate_br_deaminase
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: Glucosamine-6-phosphate deaminase Synonym: Synonym not specified Accession: P03041
member entity reference: Glucosamine-6-phosphate isomerase
member entity reference: Glucosamine-6-phosphate isomerase 2
member entity reference: Probable glucosamine-6-phosphate deaminase 2
member entity reference: Glucosamine-6-phosphate deaminase
member entity reference: Uncharacterized protein
member entity reference: Probable glucosamine-6-phosphate isomerase
member entity reference: Glucosamine-6-phosphate isomerase 1
member entity reference: Putative deaminase AgaI
member entity reference: Uncharacterized protein YieK
member entity reference: Glucosamine-6-phosphate deaminase 1

uniprot H2QRP1 84
type: UnificationXref
id: H2QRP1
db: uniprot

uniprot E2RTN3 74
type: UnificationXref
id: E2RTN3
db: uniprot

N-acetylglucosamine-6-phosphate deacetylase
type: ProteinReference
xref: uniprot Q7QBX3 20
organism: Anopheles gambiae

PARTICIPANT STOICHIOMETRY r9 173
type: Stoichiometry
physical entity: UTP
stoichiometric coefficient: 1.0

Bifunctional protein GlmU
type: ProteinReference
xref: uniprot Q9HT22 154
organism: Pseudomonas aeruginosa

PARTICIPANT STOICHIOMETRY r9 174
type: Stoichiometry
physical entity: UDP-N-acetyl-D-glucosamine
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r9 175
type: Stoichiometry
physical entity: PPi
stoichiometric coefficient: 1.0

STATE_TRANSITION_LEFT__N_acetyl_D_mannosamine_6_phosphate-RIGHT__N_acetyl_D_glucos_amine_6_phosphate-_r3
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 163
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 164
left: N-acetyl-D-mannosamine-6-phosphate
interaction type: STATE_TRANSITION
right: N-acetyl-D-glucos-amine-6-phosphate

Bacillus subtilis
type: BioSource
xref: ncbitaxon 224308 11

ncbitaxon 251221 43
type: UnificationXref
id: 251221
db: ncbitaxon

ncbitaxon 10116 19
type: UnificationXref
id: 10116
db: ncbitaxon

UDP-N-acetylglucosamine pyrophosphorylase
type: ProteinReference
xref: uniprot Q7UPM5 44
organism: Rhodopirellula baltica

ncbitaxon 9544 9
type: UnificationXref
id: 9544
db: ncbitaxon

Bos taurus
type: BioSource
xref: ncbitaxon 9913 7

uniprot Q55504 153
type: UnificationXref
id: Q55504
db: uniprot

Glucosamine-6-phosphate isomerase
type: ProteinReference
xref: uniprot E2RU05 76
organism: Giardia intestinalis

Probable N-acetylglucosamine-6-phosphate deacetylase NagA (GlcNAc 6-P deacetylase)
type: ProteinReference
xref: uniprot O53382 12
organism: Mycobacterium tuberculosis

Macaca mulatta
type: BioSource
xref: ncbitaxon 9544 9

uniprot Q9XVJ2 96
type: UnificationXref
id: Q9XVJ2
db: uniprot

Ornithorhynchus anatinus
type: BioSource
xref: ncbitaxon 9258 106

ncbitaxon 237561 5
type: UnificationXref
id: 237561
db: ncbitaxon

uniprot Q9DCJ9 65
type: UnificationXref
id: Q9DCJ9
db: uniprot

Probable glucosamine-6-phosphate isomerase
type: ProteinReference
xref: uniprot Q9XVJ2 96
organism: Caenorhabditis elegans

N-acetylglucosamine-6-phosphate deacetylase
type: Protein
entity reference: N-acetylglucosamine-6-phosphate deacetylase
comment: SPECIES_TYPE=PROTEIN

Glutamine:fructose-6-phosphate aminotransferase 1, isoform A
type: ProteinReference
xref: uniprot Q7PLC7 134
organism: Drosophila melanogaster

N-acetylneuraminate lyase
type: ProteinReference
xref: uniprot Q66H59 61
organism: Rattus norvegicus

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__N_acetylglucosamine_1_phosphate-_UTP-RIGHT__UDP_N_acetyl_D_glucosamine-_PPi-_r9
controller: N-acetylglucosamine-1-phosphate uridyltransferase

uniprot Q7QBX3 20
type: UnificationXref
id: Q7QBX3
db: uniprot

uniprot A2P2R3 98
type: UnificationXref
id: A2P2R3
db: uniprot

ncbitaxon 5722 54
type: UnificationXref
id: 5722
db: ncbitaxon

uniprot H2QPE3 83
type: UnificationXref
id: H2QPE3
db: uniprot

ncbitaxon 243090 45
type: UnificationXref
id: 243090
db: ncbitaxon

N-acetylneuraminate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

STATE_TRANSITION_LEFT__D_glucosamine_6_phosphate-RIGHT__D_glucosamine_1_phosphate-_r7
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r7 180
participant stoichiometry: PARTICIPANT STOICHIOMETRY r7 181
left: D-glucosamine-6-phosphate
interaction type: STATE_TRANSITION
right: D-glucosamine-1-phosphate

uniprot F1PGJ3 102
type: UnificationXref
id: F1PGJ3
db: uniprot

Methanosarcina acetivorans
type: BioSource
xref: ncbitaxon 188937 137

uniprot A2E8E5 53
type: UnificationXref
id: A2E8E5
db: uniprot

ncbitaxon 9913 7
type: UnificationXref
id: 9913
db: ncbitaxon

uniprot Q9WZS0 151
type: UnificationXref
id: Q9WZS0
db: uniprot

Phosphoglucosamine mutase
type: Protein
entity reference: Phosphoglucosamine mutase
comment: SPECIES_TYPE=PROTEIN

ncbitaxon 8364 81
type: UnificationXref
id: 8364
db: ncbitaxon

uniprot Q9VMP9 95
type: UnificationXref
id: Q9VMP9
db: uniprot

uniprot A0A452DIC9 67
type: UnificationXref
id: A0A452DIC9
db: uniprot

uniprot F7H603 82
type: UnificationXref
id: F7H603
db: uniprot

Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2
type: ProteinReference
xref: uniprot Q9Z2Z9 152
organism: Mus musculus

Aquifex aeolicus
type: BioSource
xref: ncbitaxon 224324 40

Canis lupus familiaris
type: BioSource
xref: ncbitaxon 9615 56

N-acetylglucosamine-6-phosphate deacetylase
type: ProteinReference
xref: uniprot Q9RZ88 29
organism: Deinococcus radiodurans

Glucosamine-6-phosphate deaminase 1
type: ProteinReference
xref: uniprot O35000 86
organism: Bacillus subtilis

UTP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__glutamine-_D_glucosamine_6_phosphate-RIGHT__glutamate-_Fructose_6_phosphate-_r5
controller: Fructose-6-phosphate aminotransferase

uniprot F7A0L7 79
type: UnificationXref
id: F7A0L7
db: uniprot

uniprot O31458 85
type: UnificationXref
id: O31458
db: uniprot

PARTICIPANT STOICHIOMETRY r4 159
type: Stoichiometry
physical entity: N-acetyl-D-glucos-amine-6-phosphate
stoichiometric coefficient: 1.0

Gallus gallus
type: BioSource
xref: ncbitaxon 9031 71

Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
type: ProteinReference
xref: uniprot P47856 119
organism: Mus musculus

Pyrobaculum aerophilum
type: BioSource
xref: ncbitaxon 178306 139

D-glucosamine-6-phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot P14742 118
type: UnificationXref
id: P14742
db: uniprot

Glucosamine-6-phosphate isomerase
type: ProteinReference
xref: uniprot E1C878 70
organism: Gallus gallus

Streptomyces coelicolor
type: BioSource
xref: ncbitaxon 100226 28

Putative deaminase AgaI
type: ProteinReference
xref: uniprot P42912 89
organism: Escherichia coli

uniprot Q8REH0 24
type: UnificationXref
id: Q8REH0
db: uniprot

uniprot Q9L065 144
type: UnificationXref
id: Q9L065
db: uniprot

STATE_TRANSITION_LEFT__ATP-_N_acetylmannosamine-RIGHT__N_acetyl_D_mannosamine_6_phosphate-_ADP-_r2
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 167
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 168
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 165
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 166
left: ATP
left: N-acetylmannosamine
interaction type: STATE_TRANSITION
right: ADP
right: N-acetyl-D-mannosamine-6-phosphate

uniprot Q8CJX6 46
type: UnificationXref
id: Q8CJX6
db: uniprot

ncbitaxon 272561 114
type: UnificationXref
id: 272561
db: ncbitaxon

H2O
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

STATE_TRANSITION
type: RelationshipTypeVocabulary

Glucosamine-6-phosphate isomerase
type: ProteinReference
xref: uniprot Q9VMP9 95
organism: Drosophila melanogaster

STATE_TRANSITION_LEFT__D_glucosamine_1_phosphate-_acetyl_CoA-RIGHT__N_acetylglucosamine_1_phosphate-_CoA-_r8
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r8 179
participant stoichiometry: PARTICIPANT STOICHIOMETRY r8 178
participant stoichiometry: PARTICIPANT STOICHIOMETRY r8 176
participant stoichiometry: PARTICIPANT STOICHIOMETRY r8 177
left: acetyl-CoA
left: D-glucosamine-1-phosphate
interaction type: STATE_TRANSITION
right: N-acetylglucosamine-1-phosphate
right: CoA

Glucosamine-6-phosphate isomerase
type: ProteinReference
xref: uniprot B5DEZ6 69
organism: Rattus norvegicus

Glutamine-Fructose 6-phosphate AminoTransferase homolog
type: ProteinReference
xref: uniprot Q19699 129
organism: Caenorhabditis elegans

Uncharacterized protein
type: ProteinReference
xref: uniprot F7B5P0 105
organism: Ornithorhynchus anatinus

N-acetyl-D-mannosamine-6-phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot Q9WXZ5 150
organism: Thermotoga maritima

uniprot Q7PTG5 62
type: UnificationXref
id: Q7PTG5
db: uniprot

uniprot Q9X1W4 51
type: UnificationXref
id: Q9X1W4
db: uniprot

uniprot Q8EZM9 47
type: UnificationXref
id: Q8EZM9
db: uniprot

uniprot E1C878 70
type: UnificationXref
id: E1C878
db: uniprot

uniprot P0AF18 14
type: UnificationXref
id: P0AF18
db: uniprot

Bifunctional protein GlmU
type: ProteinReference
xref: uniprot Q8CJX6 46
organism: Streptomyces coelicolor

Uncharacterized protein
type: ProteinReference
xref: uniprot F6TDC4 104
organism: Macaca mulatta

Bifunctional protein GlmU
type: ProteinReference
xref: uniprot Q55504 153
organism: Synechocystis

Uncharacterized protein YieK
type: ProteinReference
xref: uniprot P31470 88
organism: Escherichia coli

uniprot Q9HT22 154
type: UnificationXref
id: Q9HT22
db: uniprot

Caenorhabditis briggsae
type: BioSource
xref: ncbitaxon 6238 101

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot Q9HT00 140
organism: Halobacterium salinarum

Caenorhabditis elegans
type: BioSource
xref: ncbitaxon 6239 17

NH3
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Glucosamine-6-phosphate isomerase
type: ProteinReference
xref: uniprot H2QRP1 84
organism: Pan troglodytes

uniprot Q9Y303 35
type: UnificationXref
id: Q9Y303
db: uniprot

uniprot F7B2V6 80
type: UnificationXref
id: F7B2V6
db: uniprot

uniprot Q9BXD5 64
type: UnificationXref
id: Q9BXD5
db: uniprot

uniprot Q9RYZ9 148
type: UnificationXref
id: Q9RYZ9
db: uniprot

Glucosamine-6-phosphate isomerase 1
type: ProteinReference
xref: uniprot A4FV08 68
organism: Bos taurus

uniprot Q8REG1 91
type: UnificationXref
id: Q8REG1
db: uniprot

uniprot F6TDC4 104
type: UnificationXref
id: F6TDC4
db: uniprot

fructose-6-phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Pseudomonas aeruginosa
type: BioSource
xref: ncbitaxon 208964 26

uniprot E2RAE9 55
type: UnificationXref
id: E2RAE9
db: uniprot

GFPT2 isoform 1
type: ProteinReference
xref: uniprot K7C6M2 111
organism: Pan troglodytes

ncbitaxon 64091 141
type: UnificationXref
id: 64091
db: ncbitaxon

N-acetylglucosamine-1-phosphate uridyltransferase
type: Protein
entity reference: N-acetylglucosamine-1-phosphate uridyltransferase
comment: SPECIES_TYPE=PROTEIN

uniprot Q9LIP9 145
type: UnificationXref
id: Q9LIP9
db: uniprot

Glucosamine-6-phosphate isomerase 2
type: ProteinReference
xref: uniprot A0A452DIC9 67
organism: Bos taurus

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot P0CI73 117
organism: Bacillus subtilis

Halobacterium salinarum
type: BioSource
xref: ncbitaxon 64091 141

Fructose-6-phosphate aminotransferase
type: Protein
entity reference: Fructose-6-phosphate aminotransferase
comment: SPECIES_TYPE=PROTEIN

N-acetylneuraminate lyase
type: ProteinReference
xref: uniprot P0A6L4 59
organism: Escherichia coli

ncbitaxon 13616 78
type: UnificationXref
id: 13616
db: ncbitaxon

Anopheles gambiae
type: BioSource
xref: ncbitaxon 7165 21

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot P53704 120
organism: Candida albicans

ncbitaxon 83332 13
type: UnificationXref
id: 83332
db: ncbitaxon

UDP-N-acetylglucosamine diphosphorylase
type: ProteinReference
xref: uniprot Q8EZM9 47
organism: Leptospira interrogans

N-acetylglucosamine-1-phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Fructose-6-phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Probable glucosamine-6-phosphate deaminase 2
type: ProteinReference
xref: uniprot O31458 85
organism: Bacillus subtilis

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot P9WN49 124
organism: Mycobacterium tuberculosis

Glucosamine-1-phosphate acetyltransferase
type: Protein
entity reference: Glucosamine-1-phosphate acetyltransferase
comment: SPECIES_TYPE=PROTEIN

Chlamydia trachomatis
type: BioSource
xref: ncbitaxon 272561 114

Thermotoga maritima
type: BioSource
xref: ncbitaxon 243274 34

uniprot Q8TDQ7 92
type: UnificationXref
id: Q8TDQ7
db: uniprot

Fructose-6-phosphate aminotransferase
type: ProteinReference
xref: P03042
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: Fructose-6-phosphate aminotransferase Synonym: Synonym not specified Accession: P03042
comment: ENTITY_REFERENCE_ID_DESC=N-acetylglucosamine metabolism.PROTEIN.GENERIC.Fructose-6-phosphate_br_aminotransferase
member entity reference: Glucosamine--fructose-6-phosphate aminotransferase-related protein
member entity reference: GFPT2 isoform 1
member entity reference: Uncharacterized protein
member entity reference: Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2
member entity reference: Glutamine-Fructose 6-phosphate AminoTransferase homolog
member entity reference: Probable glutamine--fructose-6-phosphate aminotransferase [isomerizing]
member entity reference: Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
member entity reference: GH12731p
member entity reference: Glutamine--fructose-6-phosphate transaminase 1
member entity reference: Uncharacterized protein YMR085W
member entity reference: Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
member entity reference: Glutamine-fructose-6-phosphate transaminase 2
member entity reference: Putative glutamine--fructose-6-phosphate aminotransferase [isomerizing]
member entity reference: Glutamine:fructose-6-phosphate aminotransferase 1, isoform A
member entity reference: Probable aminotransferase
member entity reference: GFPT1 isoform 1
member entity reference: Protein CBG02850

uniprot O84823 113
type: UnificationXref
id: O84823
db: uniprot

ncbitaxon 190304 3
type: UnificationXref
id: 190304
db: ncbitaxon

N-acetylglucosamine-6-phosphate deacetylase
type: ProteinReference
xref: uniprot Q8JZV7 22
organism: Mus musculus

Synechocystis
type: BioSource
xref: ncbitaxon 1111708 122

uniprot B5DEZ6 69
type: UnificationXref
id: B5DEZ6
db: uniprot

N-acetylmannosamine kinase
type: Protein
entity reference: N-acetylmannosamine kinase
comment: SPECIES_TYPE=PROTEIN

N-acetylmannosamine kinase
type: ProteinReference
xref: uniprot Q8RDN7 38
organism: Fusobacterium nucleatum

N-acetylneuraminate lyase
type: ProteinReference
xref: uniprot Q8RDN6 63
organism: Fusobacterium nucleatum

Protein CBG02850
type: ProteinReference
xref: uniprot A8WTD8 100
organism: Caenorhabditis briggsae

Glucosamine-1-phosphate acetyltransferase
type: ProteinReference
xref: P03039
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: Glucosamine-1-phosphate acetyltransferase Synonym: Synonym not specified Accession: P03039
comment: ENTITY_REFERENCE_ID_DESC=N-acetylglucosamine metabolism.PROTEIN.GENERIC.Glucosamine-1-phosphate_br_acetyltransferase
member entity reference: Bifunctional protein GlmU
member entity reference: UDP-N-acetylglucosamine diphosphorylase
member entity reference: UDP-N-acetylglucosamine pyrophosphorylase

ncbitaxon 284812 127
type: UnificationXref
id: 284812
db: ncbitaxon

Glucosamine-6-phosphate isomerase
type: ProteinReference
xref: uniprot E2RH59 73
organism: Canis lupus familiaris

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot Q8TLL3 136
organism: Methanosarcina acetivorans

Monodelphis domestica
type: BioSource
xref: ncbitaxon 13616 78

ncbitaxon 83333 15
type: UnificationXref
id: 83333
db: ncbitaxon

glutamine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Glucosamine-6-phosphate isomerase 2
type: ProteinReference
xref: uniprot Q8TDQ7 92
organism: Homo sapiens

uniprot H2Q0Q9 57
type: UnificationXref
id: H2Q0Q9
db: uniprot

uniprot Q29RY9 60
type: UnificationXref
id: Q29RY9
db: uniprot

Probable glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot Q09740 126
organism: Schizosaccharomyces pombe

uniprot Q9HT25 142
type: UnificationXref
id: Q9HT25
db: uniprot

uniprot H2R176 110
type: UnificationXref
id: H2R176
db: uniprot

N-acetylmannosamine-6-phospate epimerase
type: Protein
comment: SPECIES_TYPE=PROTEIN

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot Q8RG65 135
organism: Fusobacterium nucleatum

Phosphoglucosamine mutase
type: ProteinReference
xref: P03035
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: Phosphoglucosamine mutase Synonym: Synonym not specified Accession: P03035
comment: ENTITY_REFERENCE_ID_DESC=N-acetylglucosamine metabolism.PROTEIN.GENERIC.Phosphoglucosamine_br_mutase
member entity reference: Phosphoglucosamine mutase

Schizosaccharomyces pombe
type: BioSource
xref: ncbitaxon 284812 127

P03035
type: UnificationXref
id: P03035
db: PANTHER Pathway Component

ncbitaxon 100226 28
type: UnificationXref
id: 100226
db: ncbitaxon

P03036
type: UnificationXref
id: P03036
db: PANTHER Pathway Component

ncbitaxon 188937 137
type: UnificationXref
id: 188937
db: ncbitaxon

P03039
type: UnificationXref
id: P03039
db: PANTHER Pathway Component

UDP-N-acetyl-D-glucosamine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

P03038
type: UnificationXref
id: P03038
db: PANTHER Pathway Component

Glucosamine-6-phosphate isomerase 1
type: ProteinReference
xref: uniprot P46926 90
organism: Homo sapiens

Glutamine--fructose-6-phosphate transaminase 1
type: ProteinReference
xref: uniprot F6R0B7 103
organism: Xenopus tropicalis

Glucosamine-6-phosphate isomerase
type: ProteinReference
xref: uniprot F7A0L7 79
organism: Monodelphis domestica

uniprot P0A6L4 59
type: UnificationXref
id: P0A6L4
db: uniprot

PARTICIPANT STOICHIOMETRY r1 170
type: Stoichiometry
physical entity: pyruvate
stoichiometric coefficient: 1.0

ncbitaxon 9258 106
type: UnificationXref
id: 9258
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r1 171
type: Stoichiometry
physical entity: N-acetylmannosamine
stoichiometric coefficient: 1.0

uniprot O53382 12
type: UnificationXref
id: O53382
db: uniprot

Glucosamine-6-phosphate isomerase 2
type: ProteinReference
xref: uniprot Q9CRC9 93
organism: Mus musculus

ncbitaxon 243274 34
type: UnificationXref
id: 243274
db: ncbitaxon

Glucosamine-6-phosphate isomerase
type: ProteinReference
xref: uniprot F7B2V6 80
organism: Xenopus tropicalis

ncbitaxon 9615 56
type: UnificationXref
id: 9615
db: ncbitaxon

Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2
type: ProteinReference
xref: uniprot O94808 115
organism: Homo sapiens

Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
type: ProteinReference
xref: uniprot P82808 123
organism: Rattus norvegicus

ncbitaxon 1111708 122
type: UnificationXref
id: 1111708
db: ncbitaxon

ncbitaxon 189518 48
type: UnificationXref
id: 189518
db: ncbitaxon

uniprot K7C6M2 111
type: UnificationXref
id: K7C6M2
db: uniprot

uniprot P0CF18 116
type: UnificationXref
id: P0CF18
db: uniprot

PARTICIPANT STOICHIOMETRY r1 169
type: Stoichiometry
physical entity: N-acetylneuraminate
stoichiometric coefficient: 1.0

Leptospira interrogans
type: BioSource
xref: ncbitaxon 189518 48

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot Q9L065 144
organism: Streptomyces coelicolor

PARTICIPANT STOICHIOMETRY r4 160
type: Stoichiometry
physical entity: H2O
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r4 162
type: Stoichiometry
physical entity: acetate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r4 161
type: Stoichiometry
physical entity: D-glucosamine-6-phosphate
stoichiometric coefficient: 1.0

Deinococcus radiodurans
type: BioSource
xref: ncbitaxon 243230 30

uniprot Q5BJY6 18
type: UnificationXref
id: Q5BJY6
db: uniprot

GFPT1 isoform 1
type: ProteinReference
xref: uniprot H2R176 110
organism: Pan troglodytes

Homo sapiens
type: BioSource
xref: ncbitaxon 9606 36

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot P14742 118
organism: Saccharomyces cerevisiae

uniprot Q7UPM5 44
type: UnificationXref
id: Q7UPM5
db: uniprot

Methanocaldococcus jannaschii
type: BioSource
xref: ncbitaxon 243232 132

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot Q9RXK9 147
organism: Deinococcus radiodurans

Glucosamine-6-phosphate isomerase 1
type: ProteinReference
xref: uniprot O88958 87
organism: Mus musculus

Arabidopsis thaliana
type: BioSource
xref: ncbitaxon 3702 146

uniprot O66863 39
type: UnificationXref
id: O66863
db: uniprot

Glutamine-fructose-6-phosphate transaminase 2
type: ProteinReference
xref: uniprot F1PGJ3 102
organism: Canis lupus familiaris

uniprot Q8RDN6 63
type: UnificationXref
id: Q8RDN6
db: uniprot

uniprot Q8TLL3 136
type: UnificationXref
id: Q8TLL3
db: uniprot

N-acetylneuraminate lyase
type: ProteinReference
xref: uniprot Q9DCJ9 65
organism: Mus musculus

N-acetylmannosamine kinase
type: ProteinReference
xref: uniprot P45425 37
organism: Escherichia coli

uniprot P46926 90
type: UnificationXref
id: P46926
db: uniprot

uniprot P45425 37
type: UnificationXref
id: P45425
db: uniprot

P03042
type: UnificationXref
id: P03042
db: PANTHER Pathway Component

ncbitaxon 184922 75
type: UnificationXref
id: 184922
db: ncbitaxon

Mycobacterium tuberculosis
type: BioSource
xref: ncbitaxon 83332 13

P03041
type: UnificationXref
id: P03041
db: PANTHER Pathway Component

P03040
type: UnificationXref
id: P03040
db: PANTHER Pathway Component

uniprot F6TFR5 8
type: UnificationXref
id: F6TFR5
db: uniprot

Putative N-acetylglucosamine-6-phosphate deacetylase
type: ProteinReference
xref: uniprot Q9KXV7 27
organism: Streptomyces coelicolor

uniprot P42912 89
type: UnificationXref
id: P42912
db: uniprot

ncbitaxon 6238 101
type: UnificationXref
id: 6238
db: ncbitaxon

N-acetylglucosamine-6-phosphate deacetylase
type: ProteinReference
xref: uniprot A7MBC0 6
organism: Bos taurus

Trichomonas vaginalis
type: BioSource
xref: ncbitaxon 5722 54

N-acetylglucosamine metabolism
type: Pathway
pathway component: STATE_TRANSITION_LEFT__H2O-_D_glucosamine_6_phosphate-RIGHT__fructose_6_phosphate-_NH3-_r6
pathway component: STATE_TRANSITION_LEFT__N_acetyl_D_mannosamine_6_phosphate-RIGHT__N_acetyl_D_glucos_amine_6_phosphate-_r3
pathway component: STATE_TRANSITION_LEFT__glutamine-_D_glucosamine_6_phosphate-RIGHT__glutamate-_Fructose_6_phosphate-_r5
pathway component: STATE_TRANSITION_LEFT__N_acetylneuraminate-RIGHT__pyruvate-_N_acetylmannosamine-_r1
pathway component: STATE_TRANSITION_LEFT__D_glucosamine_6_phosphate-RIGHT__D_glucosamine_1_phosphate-_r7
pathway component: STATE_TRANSITION_LEFT__ATP-_N_acetylmannosamine-RIGHT__N_acetyl_D_mannosamine_6_phosphate-_ADP-_r2
pathway component: STATE_TRANSITION_LEFT__D_glucosamine_1_phosphate-_acetyl_CoA-RIGHT__N_acetylglucosamine_1_phosphate-_CoA-_r8
pathway component: STATE_TRANSITION_LEFT__N_acetylglucosamine_1_phosphate-_UTP-RIGHT__UDP_N_acetyl_D_glucosamine-_PPi-_r9
pathway component: STATE_TRANSITION_LEFT__N_acetyl_D_glucos_amine_6_phosphate-_H2O-RIGHT__D_glucosamine_6_phosphate-_acetate-_r4
xref: PANTHER Pathway P02756 1
comment: MODEL_NOTES= Amino sugars such as N-acetylglucosamine, N-acetylmannosamine and N-acetylneuraminic acid serve multiple roles in biology. In bacteria these amino sugars are components of the peptidoglycan layer and outer membrane lipopolysaccharide layer of bacteria cell walls. They also can serve as a source of carbon and nitrogen for energy production. Website=www.biocyc.org/Ecoli/Pathways/ free text=Voet and Voet (textbook) Biochemistry

uniprot Q19130 128
type: UnificationXref
id: Q19130
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__H2O-_D_glucosamine_6_phosphate-RIGHT__fructose_6_phosphate-_NH3-_r6
controller: Glucosamine-6-phosphate deaminase

Escherichia coli
type: BioSource
xref: ncbitaxon 83333 15

P03043
type: UnificationXref
id: P03043
db: PANTHER Pathway Component

uniprot O66648 112
type: UnificationXref
id: O66648
db: uniprot

AGAP007700-PA
type: ProteinReference
xref: uniprot Q7PTG5 62
organism: Anopheles gambiae

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__N_acetyl_D_glucos_amine_6_phosphate-_H2O-RIGHT__D_glucosamine_6_phosphate-_acetate-_r4
controller: N-acetylglucosamine-6-phosphate deacetylase

Glucosamine-6-phosphate isomerase
type: ProteinReference
xref: uniprot E2QX53 72
organism: Canis lupus familiaris

PARTICIPANT STOICHIOMETRY r2 167
type: Stoichiometry
physical entity: N-acetyl-D-mannosamine-6-phosphate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r2 168
type: Stoichiometry
physical entity: ADP
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r2 165
type: Stoichiometry
physical entity: ATP
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r2 166
type: Stoichiometry
physical entity: N-acetylmannosamine
stoichiometric coefficient: 1.0

ncbitaxon 10090 23
type: UnificationXref
id: 10090
db: ncbitaxon

Uncharacterized protein
type: ProteinReference
xref: uniprot Q9WZS0 151
organism: Thermotoga maritima

acetyl-CoA
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

N-acetylglucosamine-6-phosphate deacetylase
type: ProteinReference
xref: uniprot Q9WZS1 33
organism: Thermotoga maritima

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__D_glucosamine_6_phosphate-RIGHT__D_glucosamine_1_phosphate-_r7
controller: Phosphoglucosamine mutase

uniprot P47856 119
type: UnificationXref
id: P47856
db: uniprot

N-acetylglucosamine-6-phosphate deacetylase
type: ProteinReference
xref: uniprot O34450 10
organism: Bacillus subtilis

uniprot Q8ZTZ0 138
type: UnificationXref
id: Q8ZTZ0
db: uniprot

N-acetylneuraminate lyase, putative
type: ProteinReference
xref: uniprot A2E8E5 53
organism: Trichomonas vaginalis

uniprot Q58815 131
type: UnificationXref
id: Q58815
db: uniprot

uniprot Q8JZV7 22
type: UnificationXref
id: Q8JZV7
db: uniprot

PARTICIPANT STOICHIOMETRY r8 179
type: Stoichiometry
physical entity: CoA
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r8 178
type: Stoichiometry
physical entity: N-acetylglucosamine-1-phosphate
stoichiometric coefficient: 1.0

uniprot Q09740 126
type: UnificationXref
id: Q09740
db: uniprot

Fusobacterium nucleatum
type: BioSource
xref: ncbitaxon 190304 3

uniprot A7MBC0 6
type: UnificationXref
id: A7MBC0
db: uniprot

PARTICIPANT STOICHIOMETRY r8 177
type: Stoichiometry
physical entity: acetyl-CoA
stoichiometric coefficient: 1.0

N-acetylneuraminate lyase
type: ProteinReference
xref: uniprot Q29RY9 60
organism: Bos taurus

PARTICIPANT STOICHIOMETRY r8 176
type: Stoichiometry
physical entity: D-glucosamine-1-phosphate
stoichiometric coefficient: 1.0

uniprot P72720 121
type: UnificationXref
id: P72720
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot Q5ZIG5 133
organism: Gallus gallus

uniprot Q7NNG8 42
type: UnificationXref
id: Q7NNG8
db: uniprot

uniprot F7GN87 109
type: UnificationXref
id: F7GN87
db: uniprot

ncbitaxon 178306 139
type: UnificationXref
id: 178306
db: ncbitaxon

uniprot Q5ZIG5 133
type: UnificationXref
id: Q5ZIG5
db: uniprot

uniprot A0A1D8PQG3 4
type: UnificationXref
id: A0A1D8PQG3
db: uniprot

uniprot A8WTD8 100
type: UnificationXref
id: A8WTD8
db: uniprot

uniprot Q9CRC9 93
type: UnificationXref
id: Q9CRC9
db: uniprot

uniprot F7CBS8 107
type: UnificationXref
id: F7CBS8
db: uniprot

pyruvate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ATP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot O84823 113
organism: Chlamydia trachomatis

uniprot Q66H59 61
type: UnificationXref
id: Q66H59
db: uniprot

N-acetylglucosamine-6-phosphate deacetylase
type: ProteinReference
xref: uniprot Q9Y303 35
organism: Homo sapiens

Rattus norvegicus
type: BioSource
xref: ncbitaxon 10116 19

Phosphoglucosamine mutase
type: ProteinReference
xref: uniprot Q8R6A7 2
organism: Fusobacterium nucleatum

glutamate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

N-acetylglucosamine-1-phosphate uridyltransferase
type: ProteinReference
xref: P03043
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=N-acetylglucosamine metabolism.PROTEIN.GENERIC.N-acetylglucosamine-1-_br_phosphate uridyltransferase
comment: ENTITY_REFERENCE_NOTES= Long Name: N-acetylglucosamine-1-phosphate uridyltransferase Synonym: Synonym not specified Accession: P03043
member entity reference: Bifunctional protein GlmU

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__D_glucosamine_1_phosphate-_acetyl_CoA-RIGHT__N_acetylglucosamine_1_phosphate-_CoA-_r8
controller: Glucosamine-1-phosphate acetyltransferase

ncbitaxon 9031 71
type: UnificationXref
id: 9031
db: ncbitaxon

ADP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q9WZS1 33
type: UnificationXref
id: Q9WZS1
db: uniprot

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot P72720 121
organism: Synechocystis

uniprot F7B5P0 105
type: UnificationXref
id: F7B5P0
db: uniprot

Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2
type: ProteinReference
xref: uniprot A0A452DHW0 97
organism: Bos taurus

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__ATP-_N_acetylmannosamine-RIGHT__N_acetyl_D_mannosamine_6_phosphate-_ADP-_r2
controller: N-acetylmannosamine kinase

ncbitaxon 224308 11
type: UnificationXref
id: 224308
db: ncbitaxon

N-acetylglucosamine-6-phosphate deacetylase
type: ProteinReference
xref: uniprot Q8REH0 24
organism: Fusobacterium nucleatum

Rhodopirellula baltica
type: BioSource
xref: ncbitaxon 243090 45

uniprot O35000 86
type: UnificationXref
id: O35000
db: uniprot

uniprot E2QX53 72
type: UnificationXref
id: E2QX53
db: uniprot

uniprot A0A1D5R8R9 66
type: UnificationXref
id: A0A1D5R8R9
db: uniprot

STATE_TRANSITION
type: InteractionVocabulary

PANTHER Pathway P02756 1
type: UnificationXref
id: P02756
db: PANTHER Pathway

Glucosamine-6-phosphate deaminase
type: ProteinReference
xref: uniprot Q8REG1 91
organism: Fusobacterium nucleatum

Uncharacterized protein
type: ProteinReference
xref: uniprot F7GN87 109
organism: Macaca mulatta

N-acetylglucosamine-6-phosphate deacetylase
type: ProteinReference
xref: uniprot F6TFR5 8
organism: Macaca mulatta

STATE_TRANSITION_LEFT__N_acetylneuraminate-RIGHT__pyruvate-_N_acetylmannosamine-_r1
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 171
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 170
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 169
left: N-acetylneuraminate
interaction type: STATE_TRANSITION
right: pyruvate
right: N-acetylmannosamine

Candida albicans
type: BioSource
xref: ncbitaxon 237561 5

ncbitaxon 9606 36
type: UnificationXref
id: 9606
db: ncbitaxon

N-acetylneuraminate lyase
type: ProteinReference
xref: uniprot Q9BXD5 64
organism: Homo sapiens

N-acetylneuraminate lyase
type: ProteinReference
xref: P03040
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: N-acetylneuraminate lyase Synonym: Synonym not specified Accession: P03040
comment: ENTITY_REFERENCE_ID_DESC=N-acetylglucosamine metabolism.PROTEIN.GENERIC.N-acetylneuraminate_br_lyase
member entity reference: N-acetylneuraminate pyruvate lyase
member entity reference: N-acetylneuraminate lyase
member entity reference: N-acetylneuraminate lyase, putative
member entity reference: AGAP007700-PA
member entity reference: Uncharacterized protein

uniprot Q9WXZ5 150
type: UnificationXref
id: Q9WXZ5
db: uniprot

ncbitaxon 243232 132
type: UnificationXref
id: 243232
db: ncbitaxon

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__N_acetylneuraminate-RIGHT__pyruvate-_N_acetylmannosamine-_r1
controller: N-acetylneuraminate lyase

N-acetylglucosamine-6-phosphate deacetylase
type: ProteinReference
xref: P03036
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: N-acetylglucosamine-6-phosphate deacetylase Synonym: Synonym not specified Accession: P03036
comment: ENTITY_REFERENCE_ID_DESC=N-acetylglucosamine metabolism.PROTEIN.GENERIC.N-acetylglucosamine-6-_br_phosphate deacetylase
member entity reference: N-acetylglucosamine-6-phosphate deacetylase
member entity reference: Probable N-acetylglucosamine-6-phosphate deacetylase
member entity reference: Putative N-acetylglucosamine-6-phosphate deacetylase
member entity reference: Probable N-acetylglucosamine-6-phosphate deacetylase NagA (GlcNAc 6-P deacetylase)

uniprot Q9K487 94
type: UnificationXref
id: Q9K487
db: uniprot

STATE_TRANSITION_LEFT__N_acetyl_D_glucos_amine_6_phosphate-_H2O-RIGHT__D_glucosamine_6_phosphate-_acetate-_r4
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 162
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 161
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 160
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 159
left: N-acetyl-D-glucos-amine-6-phosphate
left: H2O
interaction type: STATE_TRANSITION
right: D-glucosamine-6-phosphate
right: acetate

ncbitaxon 559292 99
type: UnificationXref
id: 559292
db: ncbitaxon

uniprot P82808 123
type: UnificationXref
id: P82808
db: uniprot

PPi
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ncbitaxon 9598 58
type: UnificationXref
id: 9598
db: ncbitaxon

Putative glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot A2P2R3 98
organism: Saccharomyces cerevisiae

N-acetylneuraminate lyase
type: Protein
entity reference: N-acetylneuraminate lyase
comment: SPECIES_TYPE=PROTEIN

uniprot P0CI73 117
type: UnificationXref
id: P0CI73
db: uniprot

uniprot Q7PLC7 134
type: UnificationXref
id: Q7PLC7
db: uniprot

uniprot Q9RXK9 147
type: UnificationXref
id: Q9RXK9
db: uniprot

Bifunctional protein GlmU
type: ProteinReference
xref: uniprot P14192 41
organism: Bacillus subtilis

uniprot A0A452DHW0 97
type: UnificationXref
id: A0A452DHW0
db: uniprot

uniprot Q8RG65 135
type: UnificationXref
id: Q8RG65
db: uniprot

uniprot Q9RW61 50
type: UnificationXref
id: Q9RW61
db: uniprot