Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot P0CI73 98
organism: Bacillus subtilis

STATE_TRANSITION_LEFT__dTDP_D_glucose-RIGHT__H2O-_dTDP_4_dehydro_6_deoxy_D_glucose-_r3
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 145
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 147
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 146
left: dTDP-D-glucose
interaction type: STATE_TRANSITION
right: dTDP-4-dehydro-6-deoxy-D-glucose
right: H2O

dTDP-glucose 4,6-dehydratase
type: ProteinReference
xref: uniprot Q7UVP4 28
organism: Rhodopirellula baltica

Halobacterium salinarum
type: BioSource
xref: ncbitaxon 64091 124

PARTICIPANT STOICHIOMETRY r3 147
type: Stoichiometry
physical entity: dTDP-4-dehydro-6-deoxy-D-glucose
stoichiometric coefficient: 1.0

ncbitaxon 189518 34
type: UnificationXref
id: 189518
db: ncbitaxon

uniprot Q9WZS0 133
type: UnificationXref
id: Q9WZS0
db: uniprot

uniprot O84823 94
type: UnificationXref
id: O84823
db: uniprot

Glucose-1-phosphate thymidylyltransferase
type: ProteinReference
xref: uniprot Q9RZB2 63
organism: Deinococcus radiodurans

Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
type: ProteinReference
xref: uniprot Q06210 108
organism: Homo sapiens

uniprot Q7NNG8 135
type: UnificationXref
id: Q7NNG8
db: uniprot

ncbitaxon 243232 114
type: UnificationXref
id: 243232
db: ncbitaxon

Gloeobacter violaceus
type: BioSource
xref: ncbitaxon 251221 27

dTDP-glucose 4,6-dehydratase
type: ProteinReference
xref: uniprot Q9RZB3 51
organism: Deinococcus radiodurans

STATE_TRANSITION_LEFT__UTP-_N_acetylglucosamine_1_phosphate-RIGHT__UDP_N_acetyl_D_glucosamine-_PPi-_r9
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r9 155
participant stoichiometry: PARTICIPANT STOICHIOMETRY r9 156
participant stoichiometry: PARTICIPANT STOICHIOMETRY r9 154
participant stoichiometry: PARTICIPANT STOICHIOMETRY r9 157
left: UTP
left: N-acetylglucosamine-1-phosphate
interaction type: STATE_TRANSITION
right: PPi
right: UDP-N-acetyl-D-glucosamine

uniprot Q8F5R1 35
type: UnificationXref
id: Q8F5R1
db: uniprot

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot P53704 101
organism: Candida albicans

UDP-galacto-pyranose mutase
type: ProteinReference
xref: P03048
standard name: UDP-galactopyranose mutase
comment: ENTITY_REFERENCE_ID_DESC=O-antigen biosynthesis.PROTEIN.GENERIC.UDP-galacto-_br_pyranose mutase
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: UDP-galactopyranose mutase Synonym: Synonym not specified Accession: P03048
member entity reference: UDP-galactopyranose mutase

PARTICIPANT STOICHIOMETRY r3 146
type: Stoichiometry
physical entity: H2O
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r3 145
type: Stoichiometry
physical entity: dTDP-D-glucose
stoichiometric coefficient: 1.0

ncbitaxon 83332 107
type: UnificationXref
id: 83332
db: ncbitaxon

uniprot K7C6M2 92
type: UnificationXref
id: K7C6M2
db: uniprot

uniprot O95455 19
type: UnificationXref
id: O95455
db: uniprot

UDP-N-acetylglucosamine diphosphorylase
type: ProteinReference
xref: uniprot Q8EZM9 138
organism: Leptospira interrogans

ncbitaxon 9615 10
type: UnificationXref
id: 9615
db: ncbitaxon

dTDP-glucose pyrophosphorylase
type: Protein
entity reference: dTDP-glucose pyrophosphorylase
comment: SPECIES_TYPE=PROTEIN

Bifunctional protein GlmU
type: ProteinReference
xref: uniprot Q9RW61 77
organism: Deinococcus radiodurans

Probable aminotransferase
type: ProteinReference
xref: uniprot Q9HXN6 126
organism: Pseudomonas aeruginosa

PARTICIPANT STOICHIOMETRY r2 150
type: Stoichiometry
physical entity: dTDP-D-glucose
stoichiometric coefficient: 1.0

uniprot Q9HT22 75
type: UnificationXref
id: Q9HT22
db: uniprot

uniprot H2Q7P8 17
type: UnificationXref
id: H2Q7P8
db: uniprot

uniprot Q7UVP4 28
type: UnificationXref
id: Q7UVP4
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__D_glucosamine_6_phosphate-RIGHT__glucosamine_1_phosphate-_r7
controller: Phosphoglucosamine mutase

PARTICIPANT STOICHIOMETRY r2 151
type: Stoichiometry
physical entity: PPi
stoichiometric coefficient: 1.0

UDP-galacto-pyranose mutase
type: Protein
entity reference: UDP-galacto-pyranose mutase
comment: SPECIES_TYPE=PROTEIN

uniprot P9WN49 106
type: UnificationXref
id: P9WN49
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__dTDP_4_dehydro_6_deoxy_D_glucose-RIGHT__dTDP_4_dehydro_6_deoxy_mannose-_r4
controller: dTDP-4-dehydrorhamnose 3,5-epimerase

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot P9WN49 106
organism: Mycobacterium tuberculosis

uniprot Q9LH76 44
type: UnificationXref
id: Q9LH76
db: uniprot

Glucose-1-phosphate thymidylyltransferase, putative
type: ProteinReference
xref: uniprot Q9RZC3 64
organism: Deinococcus radiodurans

Bifunctional protein GlmU
type: ProteinReference
xref: uniprot Q7NNG8 135
organism: Gloeobacter violaceus

uniprot Q4KMC4 112
type: UnificationXref
id: Q4KMC4
db: uniprot

Chlamydia trachomatis
type: BioSource
xref: ncbitaxon 272561 95

uniprot P14742 99
type: UnificationXref
id: P14742
db: uniprot

TDP-glucose 4,6-dehydratase
type: ProteinReference
xref: uniprot F6V878 11
organism: Ornithorhynchus anatinus

Thermotoga maritima
type: BioSource
xref: ncbitaxon 243274 66

uniprot Q19699 111
type: UnificationXref
id: Q19699
db: uniprot

Mus musculus
type: BioSource
xref: ncbitaxon 10090 41

ncbitaxon 3702 45
type: UnificationXref
id: 3702
db: ncbitaxon

Glucose-1-phosphate thymidylyltransferase
type: ProteinReference
xref: uniprot Q8A669 60
organism: Bacteroides thetaiotaomicron

dTDP-glucose 4,6-dehydratase
type: ProteinReference
xref: uniprot Q8F5L7 33
organism: Leptospira interrogans

GH12731p
type: ProteinReference
xref: uniprot Q9VAW3 131
organism: Drosophila melanogaster

Saccharomyces cerevisiae
type: BioSource
xref: ncbitaxon 559292 81

Synechocystis
type: BioSource
xref: ncbitaxon 1111708 73

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot Q8ZTZ0 121
organism: Pyrobaculum aerophilum

uniprot Q09740 109
type: UnificationXref
id: Q09740
db: uniprot

dTDP-D-glucose 4,6-dehydratase
type: ProteinReference
xref: uniprot F7H5H9 15
organism: Macaca mulatta

ncbitaxon 243274 66
type: UnificationXref
id: 243274
db: ncbitaxon

Drosophila melanogaster
type: BioSource
xref: ncbitaxon 7227 118

Glutamine-Fructose 6-phosphate AminoTransferase homolog
type: ProteinReference
xref: uniprot Q19130 110
organism: Caenorhabditis elegans

uniprot O66648 93
type: UnificationXref
id: O66648
db: uniprot

ncbitaxon 9031 116
type: UnificationXref
id: 9031
db: ncbitaxon

CoA
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q9RYZ9 130
type: UnificationXref
id: Q9RYZ9
db: uniprot

uniprot F6V878 11
type: UnificationXref
id: F6V878
db: uniprot

uniprot A0A3Q1LGU2 4
type: UnificationXref
id: A0A3Q1LGU2
db: uniprot

STATE_TRANSITION_LEFT__D_glucosamine_6_phosphate-RIGHT__glucosamine_1_phosphate-_r7
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r7 163
participant stoichiometry: PARTICIPANT STOICHIOMETRY r7 162
left: D-glucosamine-6-phosphate
interaction type: STATE_TRANSITION
right: glucosamine-1-phosphate

uniprot F7FMF5 89
type: UnificationXref
id: F7FMF5
db: uniprot

uniprot Q8THQ2 36
type: UnificationXref
id: Q8THQ2
db: uniprot

uniprot Q9SYM5 52
type: UnificationXref
id: Q9SYM5
db: uniprot

Bifunctional protein GlmU
type: ProteinReference
xref: uniprot O66863 69
organism: Aquifex aeolicus

Protein CBG02850
type: ProteinReference
xref: uniprot A8WTD8 82
organism: Caenorhabditis briggsae

uniprot Q7NGD4 58
type: UnificationXref
id: Q7NGD4
db: uniprot

ncbitaxon 208964 76
type: UnificationXref
id: 208964
db: ncbitaxon

Glucosamine-1-phosphate acetyltransferase
type: Protein
entity reference: Glucosamine-1-phosphate acetyltransferase
comment: SPECIES_TYPE=PROTEIN

Glucose-1-phosphate thymidylyltransferase
type: ProteinReference
xref: uniprot Q9WZW6 65
organism: Thermotoga maritima

Acetyl-CoA
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r1 153
type: Stoichiometry
physical entity: UDP-D-galacto-1,4-furanose
stoichiometric coefficient: 1.0

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot Q8TLL3 120
organism: Methanosarcina acetivorans

ncbitaxon 100226 48
type: UnificationXref
id: 100226
db: ncbitaxon

dTDP-glucose 4,6-dehydratase
type: Protein
entity reference: dTDP-glucose 4,6-dehydratase
comment: SPECIES_TYPE=PROTEIN

PARTICIPANT STOICHIOMETRY r1 152
type: Stoichiometry
physical entity: UDP-galactose
stoichiometric coefficient: 1.0

Monodelphis domestica
type: BioSource
xref: ncbitaxon 13616 14

Glutamine-fructose-6-phosphate transaminase 2
type: ProteinReference
xref: uniprot Q9LIP9 128
organism: Arabidopsis thaliana

Glucose-1-phosphate thymidylyltransferase
type: ProteinReference
xref: uniprot Q7NGD4 58
organism: Gloeobacter violaceus

fructose-6-phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Bifunctional protein GlmU
type: ProteinReference
xref: uniprot Q9X1W4 78
organism: Thermotoga maritima

Probable glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot Q09740 109
organism: Schizosaccharomyces pombe

Bacteroides thetaiotaomicron
type: BioSource
xref: ncbitaxon 226186 31

dTDP-4-dehydrorhamnose reductase
type: Protein
comment: SPECIES_TYPE=PROTEIN

uniprot Q9RWF7 49
type: UnificationXref
id: Q9RWF7
db: uniprot

dTDP-glucose 4,6-dehydratase
type: ProteinReference
xref: uniprot Q7NNE3 26
organism: Gloeobacter violaceus

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot Q8RG65 119
organism: Fusobacterium nucleatum

UDP-glucose 4-epimerase, putative
type: ProteinReference
xref: uniprot Q9RWF7 49
organism: Deinococcus radiodurans

uniprot O94808 96
type: UnificationXref
id: O94808
db: uniprot

Schizosaccharomyces pombe
type: BioSource
xref: ncbitaxon 284812 43

ncbitaxon 226186 31
type: UnificationXref
id: 226186
db: ncbitaxon

TDP-glucose 4,6-dehydratase
type: ProteinReference
xref: uniprot E2QWQ8 9
organism: Canis lupus familiaris

uniprot Q7PLC7 117
type: UnificationXref
id: Q7PLC7
db: uniprot

N-acetylglucosamine-1-phosphate uridyltransferase
type: Protein
entity reference: N-acetylglucosamine-1-phosphate uridyltransferase
comment: SPECIES_TYPE=PROTEIN

uniprot Q8TJK5 38
type: UnificationXref
id: Q8TJK5
db: uniprot

Glucose-1-phosphate thymidylyltransferase
type: ProteinReference
xref: uniprot Q7NJP9 59
organism: Gloeobacter violaceus

uniprot P72720 103
type: UnificationXref
id: P72720
db: uniprot

UDP-galactopyranose mutase
type: ProteinReference
xref: uniprot P37747 67
organism: Escherichia coli

uniprot F6R0B7 84
type: UnificationXref
id: F6R0B7
db: uniprot

Glucose-1-phosphate thymidylyltransferase 1
type: ProteinReference
xref: uniprot P37744 54
organism: Escherichia coli

glutamate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Pan troglodytes
type: BioSource
xref: ncbitaxon 9598 18

uniprot Q9RZB3 51
type: UnificationXref
id: Q9RZB3
db: uniprot

Glutamine--fructose-6-phosphate transaminase 1
type: ProteinReference
xref: uniprot F6R0B7 84
organism: Xenopus tropicalis

Xenopus tropicalis
type: BioSource
xref: ncbitaxon 8364 85

Uncharacterized protein PB2B2.11
type: ProteinReference
xref: uniprot Q9HDU4 42
organism: Schizosaccharomyces pombe

TDP-glucose 4,6-dehydratase
type: ProteinReference
xref: uniprot H2Q7P8 17
organism: Pan troglodytes

Bifunctional protein GlmU
type: ProteinReference
xref: uniprot Q8RHM3 74
organism: Fusobacterium nucleatum

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__TTP-_D_glucose_1_phosphate-RIGHT__dTDP_D_glucose-_PPi-_r2
controller: dTDP-glucose pyrophosphorylase

Uncharacterized protein
type: ProteinReference
xref: uniprot F7FMF5 89
organism: Monodelphis domestica

uniprot P61887 57
type: UnificationXref
id: P61887
db: uniprot

uniprot Q7UPM5 136
type: UnificationXref
id: Q7UPM5
db: uniprot

Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2
type: ProteinReference
xref: uniprot O94808 96
organism: Homo sapiens

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__dTDP_D_glucose-RIGHT__H2O-_dTDP_4_dehydro_6_deoxy_D_glucose-_r3
controller: dTDP-glucose 4,6-dehydratase

Phosphoglucosamine mutase
type: Protein
entity reference: Phosphoglucosamine mutase
comment: SPECIES_TYPE=PROTEIN

Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
type: ProteinReference
xref: uniprot P82808 104
organism: Rattus norvegicus

uniprot Q8AAK1 61
type: UnificationXref
id: Q8AAK1
db: uniprot

uniprot Q19130 110
type: UnificationXref
id: Q19130
db: uniprot

uniprot P0CF18 97
type: UnificationXref
id: P0CF18
db: uniprot

D-glucose-1-phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q8EZM9 138
type: UnificationXref
id: Q8EZM9
db: uniprot

D-glucosamine-6-phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot Q9L065 127
organism: Streptomyces coelicolor

Leptospira interrogans
type: BioSource
xref: ncbitaxon 189518 34

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot O66648 93
organism: Aquifex aeolicus

Deinococcus radiodurans
type: BioSource
xref: ncbitaxon 243230 50

GFPT1 isoform 1
type: ProteinReference
xref: uniprot H2R176 91
organism: Pan troglodytes

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot P14742 99
organism: Saccharomyces cerevisiae

ncbitaxon 9544 16
type: UnificationXref
id: 9544
db: ncbitaxon

Homo sapiens
type: BioSource
xref: ncbitaxon 9606 20

P03051
type: UnificationXref
id: P03051
db: PANTHER Pathway Component

Methanocaldococcus jannaschii
type: BioSource
xref: ncbitaxon 243232 114

ncbitaxon 7227 118
type: UnificationXref
id: 7227
db: ncbitaxon

dTDP-glucose 4,6-dehydratase
type: ProteinReference
xref: uniprot Q8A670 30
organism: Bacteroides thetaiotaomicron

P03052
type: UnificationXref
id: P03052
db: PANTHER Pathway Component

ncbitaxon 559292 81
type: UnificationXref
id: 559292
db: ncbitaxon

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot Q9RXK9 129
organism: Deinococcus radiodurans

uniprot P39629 56
type: UnificationXref
id: P39629
db: uniprot

uniprot P53704 101
type: UnificationXref
id: P53704
db: uniprot

Arabidopsis thaliana
type: BioSource
xref: ncbitaxon 3702 45

uniprot Q9RJE3 47
type: UnificationXref
id: Q9RJE3
db: uniprot

Glucose-1-phosphate thymidylyltransferase
type: ProteinReference
xref: uniprot Q8TNU5 62
organism: Methanosarcina acetivorans

Uncharacterized protein YMR085W
type: ProteinReference
xref: uniprot P0CF18 97
organism: Saccharomyces cerevisiae

Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2
type: ProteinReference
xref: uniprot Q4KMC4 112
organism: Rattus norvegicus

Glutamine-fructose-6-phosphate transaminase 2
type: ProteinReference
xref: uniprot F1PGJ3 83
organism: Canis lupus familiaris

dTDP-glucose 4,6-dehydratase
type: ProteinReference
xref: uniprot Q8TNU3 39
organism: Methanosarcina acetivorans

uniprot G1UB20 53
type: UnificationXref
id: G1UB20
db: uniprot

uniprot Q8F5L7 33
type: UnificationXref
id: Q8F5L7
db: uniprot

ncbitaxon 8364 85
type: UnificationXref
id: 8364
db: ncbitaxon

ncbitaxon 251221 27
type: UnificationXref
id: 251221
db: ncbitaxon

Glucosamine--fructose-6-phosphate aminotransferase-related protein
type: ProteinReference
xref: uniprot Q9RYZ9 130
organism: Deinococcus radiodurans

STATE_TRANSITION_LEFT__UDP_galactose-RIGHT__UDP_D_galacto_1,4_furanose-_r1
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 152
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 153
left: UDP-galactose
interaction type: STATE_TRANSITION
right: UDP-D-galacto-1,4-furanose

uniprot Q9WXZ5 132
type: UnificationXref
id: Q9WXZ5
db: uniprot

uniprot Q8TLL3 120
type: UnificationXref
id: Q8TLL3
db: uniprot

Mycobacterium tuberculosis
type: BioSource
xref: ncbitaxon 83332 107

ncbitaxon 178306 122
type: UnificationXref
id: 178306
db: ncbitaxon

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__glucosamine_1_phosphate-_Acetyl_CoA-RIGHT__CoA-_N_acetylglucosamine_1_phosphate-_r8
controller: Glucosamine-1-phosphate acetyltransferase

Nucleoside-diphosphate-sugar epimerase
type: ProteinReference
xref: uniprot Q8F5R1 35
organism: Leptospira interrogans

O-antigen biosynthesis
type: Pathway
pathway component: STATE_TRANSITION_LEFT__glutamine-_fructose_6_phosphate-RIGHT__glutamate-_D_glucosamine_6_phosphate-_r6
pathway component: STATE_TRANSITION_LEFT__dTDP_4_dehydro_6_deoxy_D_glucose-RIGHT__dTDP_4_dehydro_6_deoxy_mannose-_r4
pathway component: STATE_TRANSITION_LEFT__UTP-_N_acetylglucosamine_1_phosphate-RIGHT__UDP_N_acetyl_D_glucosamine-_PPi-_r9
pathway component: STATE_TRANSITION_LEFT__TTP-_D_glucose_1_phosphate-RIGHT__dTDP_D_glucose-_PPi-_r2
pathway component: STATE_TRANSITION_LEFT__D_glucosamine_6_phosphate-RIGHT__glucosamine_1_phosphate-_r7
pathway component: STATE_TRANSITION_LEFT__dTDP_D_glucose-RIGHT__H2O-_dTDP_4_dehydro_6_deoxy_D_glucose-_r3
pathway component: STATE_TRANSITION_LEFT__glucosamine_1_phosphate-_Acetyl_CoA-RIGHT__CoA-_N_acetylglucosamine_1_phosphate-_r8
pathway component: STATE_TRANSITION_LEFT__UDP_galactose-RIGHT__UDP_D_galacto_1,4_furanose-_r1
pathway component: STATE_TRANSITION_LEFT__dTDP_4_dehydro_6_deoxy_mannose-_NADPH-RIGHT__dTDP_L_rhamnose-_NADP-_r5
xref: PANTHER Pathway P02757 1
comment: MODEL_NOTES= Lipopolysaccaride is a three domain structure that is a major component of the bacterial outer membrane. One of the domains is O antigen. O-antigen is a polymer of four derivatized sugars: glucose, N-acetylglucosamine, galactose and rhamnose. Website=www.biocyc.org/Ecoli/Pathways/ free text=Voet and Voet (textbook) Biochemistry

P03049
type: UnificationXref
id: P03049
db: PANTHER Pathway Component

P03048
type: UnificationXref
id: P03048
db: PANTHER Pathway Component

P03046
type: UnificationXref
id: P03046
db: PANTHER Pathway Component

P03045
type: UnificationXref
id: P03045
db: PANTHER Pathway Component

PANTHER Pathway P02757 1
type: UnificationXref
id: P02757
db: PANTHER Pathway

P03044
type: UnificationXref
id: P03044
db: PANTHER Pathway Component

Escherichia coli
type: BioSource
xref: ncbitaxon 83333 55

uniprot P39630 21
type: UnificationXref
id: P39630
db: uniprot

uniprot Q9L065 127
type: UnificationXref
id: Q9L065
db: uniprot

PARTICIPANT STOICHIOMETRY r9 154
type: Stoichiometry
physical entity: UTP
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r9 155
type: Stoichiometry
physical entity: N-acetylglucosamine-1-phosphate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r9 156
type: Stoichiometry
physical entity: UDP-N-acetyl-D-glucosamine
stoichiometric coefficient: 1.0

uniprot Q9RXK9 129
type: UnificationXref
id: Q9RXK9
db: uniprot

Glutamine--fructose-6-phosphate transaminase 1
type: ProteinReference
xref: uniprot F7CBS8 88
organism: Monodelphis domestica

PARTICIPANT STOICHIOMETRY r9 157
type: Stoichiometry
physical entity: PPi
stoichiometric coefficient: 1.0

UDP-galactose
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

TDP-glucose 4,6-dehydratase
type: ProteinReference
xref: uniprot F7CQ20 13
organism: Monodelphis domestica

H2O
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot A2P2R3 80
type: UnificationXref
id: A2P2R3
db: uniprot

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot Q9HT25 125
organism: Pseudomonas aeruginosa

ncbitaxon 9606 20
type: UnificationXref
id: 9606
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r8 161
type: Stoichiometry
physical entity: N-acetylglucosamine-1-phosphate
stoichiometric coefficient: 1.0

Uncharacterized protein
type: ProteinReference
xref: uniprot Q9WZS0 133
organism: Thermotoga maritima

PARTICIPANT STOICHIOMETRY r8 160
type: Stoichiometry
physical entity: CoA
stoichiometric coefficient: 1.0

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot Q58815 113
organism: Methanocaldococcus jannaschii

uniprot Q8A670 30
type: UnificationXref
id: Q8A670
db: uniprot

uniprot Q9HT25 125
type: UnificationXref
id: Q9HT25
db: uniprot

uniprot P14192 71
type: UnificationXref
id: P14192
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__dTDP_4_dehydro_6_deoxy_mannose-_NADPH-RIGHT__dTDP_L_rhamnose-_NADP-_r5
controller: dTDP-4-dehydrorhamnose reductase

uniprot Q7NNE3 26
type: UnificationXref
id: Q7NNE3
db: uniprot

UDP-N-acetyl-D-glucosamine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r5 140
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

uniprot F7B5P0 87
type: UnificationXref
id: F7B5P0
db: uniprot

uniprot Q7NJP9 59
type: UnificationXref
id: Q7NJP9
db: uniprot

PARTICIPANT STOICHIOMETRY r5 141
type: Stoichiometry
physical entity: dTDP-L-rhamnose
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r5 142
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

dTDP-D-glucose 4,6-dehydratase
type: ProteinReference
xref: uniprot O95455 19
organism: Homo sapiens

uniprot Q8ZTZ0 121
type: UnificationXref
id: Q8ZTZ0
db: uniprot

Bifunctional protein GlmU
type: ProteinReference
xref: uniprot Q9HT22 75
organism: Pseudomonas aeruginosa

dTDP-4-dehydro-6-deoxy-mannose
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q5ZIG5 115
type: UnificationXref
id: Q5ZIG5
db: uniprot

uniprot Q55504 72
type: UnificationXref
id: Q55504
db: uniprot

uniprot Q06210 108
type: UnificationXref
id: Q06210
db: uniprot

Bacillus subtilis
type: BioSource
xref: ncbitaxon 224308 22

Fusobacterium nucleatum
type: BioSource
xref: ncbitaxon 190304 3

UDP-N-acetylglucosamine pyrophosphorylase
type: ProteinReference
xref: uniprot Q7UPM5 136
organism: Rhodopirellula baltica

uniprot P37747 67
type: UnificationXref
id: P37747
db: uniprot

uniprot Q58815 113
type: UnificationXref
id: Q58815
db: uniprot

Bos taurus
type: BioSource
xref: ncbitaxon 9913 5

uniprot Q8VDR7 40
type: UnificationXref
id: Q8VDR7
db: uniprot

Macaca mulatta
type: BioSource
xref: ncbitaxon 9544 16

Glucose-1-phosphate thymidylyltransferase
type: ProteinReference
xref: uniprot Q8AAK1 61
organism: Bacteroides thetaiotaomicron

ncbitaxon 64091 124
type: UnificationXref
id: 64091
db: ncbitaxon

ncbitaxon 272561 95
type: UnificationXref
id: 272561
db: ncbitaxon

Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM3
type: ProteinReference
xref: uniprot Q9LH76 44
organism: Arabidopsis thaliana

ncbitaxon 9598 18
type: UnificationXref
id: 9598
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r5 139
type: Stoichiometry
physical entity: dTDP-4-dehydro-6-deoxy-mannose
stoichiometric coefficient: 1.0

Uncharacterized protein
type: ProteinReference
xref: uniprot Q5ZIG5 115
organism: Gallus gallus

uniprot Q9RZC3 64
type: UnificationXref
id: Q9RZC3
db: uniprot

STATE_TRANSITION_LEFT__TTP-_D_glucose_1_phosphate-RIGHT__dTDP_D_glucose-_PPi-_r2
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 148
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 150
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 151
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 149
left: D-glucose-1-phosphate
left: TTP
interaction type: STATE_TRANSITION
right: dTDP-D-glucose
right: PPi

Ornithorhynchus anatinus
type: BioSource
xref: ncbitaxon 9258 12

Uncharacterized protein
type: ProteinReference
xref: uniprot Q20697 25
organism: Caenorhabditis elegans

ncbitaxon 243230 50
type: UnificationXref
id: 243230
db: ncbitaxon

Glutamine:fructose-6-phosphate aminotransferase 1, isoform A
type: ProteinReference
xref: uniprot Q7PLC7 117
organism: Drosophila melanogaster

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__glutamine-_fructose_6_phosphate-RIGHT__glutamate-_D_glucosamine_6_phosphate-_r6
controller: Fructose-6-phosphate aminotransferase

uniprot Q9RW61 77
type: UnificationXref
id: Q9RW61
db: uniprot

Glucose-1-phosphate thymidylyltransferase
type: ProteinReference
xref: uniprot G1UB20 53
organism: Leptospira interrogans

PARTICIPANT STOICHIOMETRY r8 159
type: Stoichiometry
physical entity: Acetyl-CoA
stoichiometric coefficient: 1.0

uniprot A8WTD8 82
type: UnificationXref
id: A8WTD8
db: uniprot

dTDP-4-dehydrorhamnose 3,5-epimerase
type: Protein
comment: SPECIES_TYPE=PROTEIN

ncbitaxon 284812 43
type: UnificationXref
id: 284812
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r8 158
type: Stoichiometry
physical entity: glucosamine-1-phosphate
stoichiometric coefficient: 1.0

ncbitaxon 83333 55
type: UnificationXref
id: 83333
db: ncbitaxon

dTDP-glucose 4,6-dehydratase
type: ProteinReference
xref: uniprot Q8AAJ8 32
organism: Bacteroides thetaiotaomicron

ncbitaxon 10116 105
type: UnificationXref
id: 10116
db: ncbitaxon

Protein CBG14085
type: ProteinReference
xref: uniprot A8XJB2 8
organism: Caenorhabditis briggsae

UTP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Methanosarcina acetivorans
type: BioSource
xref: ncbitaxon 188937 37

uniprot F6TDC4 86
type: UnificationXref
id: F6TDC4
db: uniprot

uniprot Q9X1W4 78
type: UnificationXref
id: Q9X1W4
db: uniprot

uniprot E2QWQ8 9
type: UnificationXref
id: E2QWQ8
db: uniprot

ncbitaxon 190304 3
type: UnificationXref
id: 190304
db: ncbitaxon

dTDP-4-dehydro-6-deoxy-D-glucose
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

dTDP-glucose 4,6-dehydratase
type: ProteinReference
xref: uniprot Q8TJK5 38
organism: Methanosarcina acetivorans

uniprot O66863 69
type: UnificationXref
id: O66863
db: uniprot

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot O84823 94
organism: Chlamydia trachomatis

Fructose-6-phosphate aminotransferase
type: ProteinReference
xref: P03051
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=O-antigen biosynthesis.PROTEIN.GENERIC.Fructose-6-phosphate_br_aminotransferase
comment: ENTITY_REFERENCE_NOTES= Long Name: Fructose-6-phosphate aminotransferase Synonym: Synonym not specified Accession: P03051
member entity reference: Uncharacterized protein
member entity reference: Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
member entity reference: Glutamine--fructose-6-phosphate transaminase 1
member entity reference: GH12731p
member entity reference: Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2
member entity reference: Glutamine:fructose-6-phosphate aminotransferase 1, isoform A
member entity reference: GFPT2 isoform 1
member entity reference: Glutamine-fructose-6-phosphate transaminase 2
member entity reference: Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
member entity reference: Glutamine-Fructose 6-phosphate AminoTransferase homolog
member entity reference: Protein CBG02850
member entity reference: Probable glutamine--fructose-6-phosphate aminotransferase [isomerizing]
member entity reference: Probable aminotransferase
member entity reference: Glucosamine--fructose-6-phosphate aminotransferase-related protein
member entity reference: Uncharacterized protein YMR085W
member entity reference: GFPT1 isoform 1
member entity reference: Putative glutamine--fructose-6-phosphate aminotransferase [isomerizing]

ncbitaxon 13616 14
type: UnificationXref
id: 13616
db: ncbitaxon

Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2
type: ProteinReference
xref: uniprot Q9Z2Z9 134
organism: Mus musculus

Rattus norvegicus
type: BioSource
xref: ncbitaxon 10116 105

uniprot P0CI73 98
type: UnificationXref
id: P0CI73
db: uniprot

Aquifex aeolicus
type: BioSource
xref: ncbitaxon 224324 70

Phosphoglucosamine mutase
type: ProteinReference
xref: uniprot Q8R6A7 2
organism: Fusobacterium nucleatum

uniprot Q8TNU3 39
type: UnificationXref
id: Q8TNU3
db: uniprot

uniprot Q9Z2Z9 134
type: UnificationXref
id: Q9Z2Z9
db: uniprot

Canis lupus familiaris
type: BioSource
xref: ncbitaxon 9615 10

uniprot Q9VAW3 131
type: UnificationXref
id: Q9VAW3
db: uniprot

dTDP-glucose 4,6-dehydratase
type: ProteinReference
xref: P03045
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: dTDP-glucose 4,6-dehydratase Synonym: Synonym not specified Accession: P03045
comment: ENTITY_REFERENCE_ID_DESC=O-antigen biosynthesis.PROTEIN.GENERIC.dTDP-glucose_br_4,6-dehydratase
member entity reference: dTDP-D-glucose 4,6-dehydratase
member entity reference: Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM2
member entity reference: Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM3
member entity reference: TDP-glucose 4,6-dehydratase
member entity reference: dTDP-glucose 4,6-dehydratase
member entity reference: Uncharacterized protein
member entity reference: Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM1
member entity reference: Protein CBG14085
member entity reference: Uncharacterized protein PB2B2.11
member entity reference: Protein CBG03656
member entity reference: UDP-glucose 4-epimerase, putative
member entity reference: Nucleoside-diphosphate-sugar epimerase

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot P72720 103
organism: Synechocystis

PPi
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot F1PGJ3 83
type: UnificationXref
id: F1PGJ3
db: uniprot

Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2
type: ProteinReference
xref: uniprot A0A452DHW0 79
organism: Bos taurus

UDP-galactopyranose mutase
type: ProteinReference
xref: uniprot Q9RYF1 68
organism: Deinococcus radiodurans

ncbitaxon 237561 102
type: UnificationXref
id: 237561
db: ncbitaxon

Gallus gallus
type: BioSource
xref: ncbitaxon 9031 116

uniprot P37744 54
type: UnificationXref
id: P37744
db: uniprot

Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
type: ProteinReference
xref: uniprot P47856 100
organism: Mus musculus

Pyrobaculum aerophilum
type: BioSource
xref: ncbitaxon 178306 122

uniprot Q9HXN6 126
type: UnificationXref
id: Q9HXN6
db: uniprot

STATE_TRANSITION_LEFT__glucosamine_1_phosphate-_Acetyl_CoA-RIGHT__CoA-_N_acetylglucosamine_1_phosphate-_r8
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r8 158
participant stoichiometry: PARTICIPANT STOICHIOMETRY r8 160
participant stoichiometry: PARTICIPANT STOICHIOMETRY r8 159
participant stoichiometry: PARTICIPANT STOICHIOMETRY r8 161
left: Acetyl-CoA
left: glucosamine-1-phosphate
interaction type: STATE_TRANSITION
right: CoA
right: N-acetylglucosamine-1-phosphate

Glucosamine-1-phosphate acetyltransferase
type: ProteinReference
xref: P03049
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=O-antigen biosynthesis.PROTEIN.GENERIC.Glucosamine-1-phosphate_br_acetyltransferase
comment: ENTITY_REFERENCE_NOTES= Long Name: Glucosamine-1-phosphate acetyltransferase Synonym: Synonym not specified Accession: P03049
member entity reference: Bifunctional protein GlmU

dTDP-glucose 4,6-dehydratase
type: ProteinReference
xref: uniprot Q8THQ2 36
organism: Methanosarcina acetivorans

N-acetylglucosamine-1-phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Phosphoglucosamine mutase
type: ProteinReference
xref: P03044
comment: ENTITY_REFERENCE_ID_DESC=O-antigen biosynthesis.PROTEIN.GENERIC.Phosphoglucosamine_br_mutase
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: Phosphoglucosamine mutase Synonym: Synonym not specified Accession: P03044
member entity reference: Phosphoglucosamine mutase

Rhodopirellula baltica
type: BioSource
xref: ncbitaxon 243090 29

ncbitaxon 6239 24
type: UnificationXref
id: 6239
db: ncbitaxon

Streptomyces coelicolor
type: BioSource
xref: ncbitaxon 100226 48

uniprot F7H5H9 15
type: UnificationXref
id: F7H5H9
db: uniprot

uniprot Q9HT00 123
type: UnificationXref
id: Q9HT00
db: uniprot

ncbitaxon 243090 29
type: UnificationXref
id: 243090
db: ncbitaxon

STATE_TRANSITION
type: RelationshipTypeVocabulary

STATE_TRANSITION
type: InteractionVocabulary

ncbitaxon 9913 5
type: UnificationXref
id: 9913
db: ncbitaxon

glucosamine-1-phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__UTP-_N_acetylglucosamine_1_phosphate-RIGHT__UDP_N_acetyl_D_glucosamine-_PPi-_r9
controller: N-acetylglucosamine-1-phosphate uridyltransferase

Uncharacterized protein
type: ProteinReference
xref: uniprot Q17556 23
organism: Caenorhabditis elegans

Uncharacterized protein
type: ProteinReference
xref: uniprot F7GN87 90
organism: Macaca mulatta

STATE_TRANSITION_LEFT__dTDP_4_dehydro_6_deoxy_mannose-_NADPH-RIGHT__dTDP_L_rhamnose-_NADP-_r5
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 141
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 142
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 139
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 140
left: dTDP-4-dehydro-6-deoxy-mannose
left: NADPH
interaction type: STATE_TRANSITION
right: dTDP-L-rhamnose
right: NADP

ncbitaxon 1111708 73
type: UnificationXref
id: 1111708
db: ncbitaxon

uniprot Q8TNU5 62
type: UnificationXref
id: Q8TNU5
db: uniprot

dTDP-L-rhamnose
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

N-acetylglucosamine-1-phosphate uridyltransferase
type: ProteinReference
xref: P03052
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: N-acetylglucosamine-1-phosphate uridyltransferase Synonym: Synonym not specified Accession: P03052
comment: ENTITY_REFERENCE_ID_DESC=O-antigen biosynthesis.PROTEIN.GENERIC.N-acetylglucosamine-1-_br_phosphate uridyltransferase
member entity reference: UDP-N-acetylglucosamine pyrophosphorylase
member entity reference: Bifunctional protein GlmU
member entity reference: UDP-N-acetylglucosamine diphosphorylase

Glucose-1-phosphate thymidylyltransferase 2
type: ProteinReference
xref: uniprot P61887 57
organism: Escherichia coli

PARTICIPANT STOICHIOMETRY r4 144
type: Stoichiometry
physical entity: dTDP-4-dehydro-6-deoxy-mannose
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r4 143
type: Stoichiometry
physical entity: dTDP-4-dehydro-6-deoxy-D-glucose
stoichiometric coefficient: 1.0

dTDP-glucose pyrophosphorylase
type: ProteinReference
xref: P03046
comment: ENTITY_REFERENCE_ID_DESC=O-antigen biosynthesis.PROTEIN.GENERIC.dTDP-glucose_br_pyrophosphorylase
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: dTDP-glucose pyrophosphorylase Synonym: Synonym not specified Accession: P03046
member entity reference: Glucose-1-phosphate thymidylyltransferase
member entity reference: Glucose-1-phosphate thymidylyltransferase 2
member entity reference: Glucose-1-phosphate thymidylyltransferase 1
member entity reference: Glucose-1-phosphate thymidylyltransferase, putative

STATE_TRANSITION_LEFT__glutamine-_fructose_6_phosphate-RIGHT__glutamate-_D_glucosamine_6_phosphate-_r6
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 164
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 165
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 167
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 166
left: fructose-6-phosphate
left: glutamine
interaction type: STATE_TRANSITION
right: D-glucosamine-6-phosphate
right: glutamate

Glutamine-Fructose 6-phosphate AminoTransferase homolog
type: ProteinReference
xref: uniprot Q19699 111
organism: Caenorhabditis elegans

Candida albicans
type: BioSource
xref: ncbitaxon 237561 102

Uncharacterized protein
type: ProteinReference
xref: uniprot F7B5P0 87
organism: Ornithorhynchus anatinus

dTDP-glucose 4,6-dehydratase
type: ProteinReference
xref: uniprot Q9RJE3 47
organism: Streptomyces coelicolor

uniprot Q17556 23
type: UnificationXref
id: Q17556
db: uniprot

ncbitaxon 224324 70
type: UnificationXref
id: 224324
db: ncbitaxon

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot Q9WXZ5 132
organism: Thermotoga maritima

TTP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

dTDP-D-glucose
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot A8WVJ0 6
type: UnificationXref
id: A8WVJ0
db: uniprot

uniprot Q8A669 60
type: UnificationXref
id: Q8A669
db: uniprot

uniprot Q8AAJ8 32
type: UnificationXref
id: Q8AAJ8
db: uniprot

uniprot A8XJB2 8
type: UnificationXref
id: A8XJB2
db: uniprot

uniprot Q9HDU4 42
type: UnificationXref
id: Q9HDU4
db: uniprot

uniprot Q9LPG6 46
type: UnificationXref
id: Q9LPG6
db: uniprot

STATE_TRANSITION_LEFT__dTDP_4_dehydro_6_deoxy_D_glucose-RIGHT__dTDP_4_dehydro_6_deoxy_mannose-_r4
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 144
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 143
left: dTDP-4-dehydro-6-deoxy-D-glucose
interaction type: STATE_TRANSITION
right: dTDP-4-dehydro-6-deoxy-mannose

uniprot Q20697 25
type: UnificationXref
id: Q20697
db: uniprot

ncbitaxon 9258 12
type: UnificationXref
id: 9258
db: ncbitaxon

uniprot A0A452DHW0 79
type: UnificationXref
id: A0A452DHW0
db: uniprot

Bifunctional protein GlmU
type: ProteinReference
xref: uniprot Q8CJX6 137
organism: Streptomyces coelicolor

Uncharacterized protein
type: ProteinReference
xref: uniprot F6TDC4 86
organism: Macaca mulatta

PARTICIPANT STOICHIOMETRY r7 163
type: Stoichiometry
physical entity: glucosamine-1-phosphate
stoichiometric coefficient: 1.0

uniprot Q9WZW6 65
type: UnificationXref
id: Q9WZW6
db: uniprot

PARTICIPANT STOICHIOMETRY r7 162
type: Stoichiometry
physical entity: D-glucosamine-6-phosphate
stoichiometric coefficient: 1.0

uniprot Q9LIP9 128
type: UnificationXref
id: Q9LIP9
db: uniprot

Glucose-1-phosphate thymidylyltransferase
type: ProteinReference
xref: uniprot P39629 56
organism: Bacillus subtilis

Bifunctional protein GlmU
type: ProteinReference
xref: uniprot Q55504 72
organism: Synechocystis

PARTICIPANT STOICHIOMETRY r6 167
type: Stoichiometry
physical entity: D-glucosamine-6-phosphate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r6 166
type: Stoichiometry
physical entity: glutamate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r2 148
type: Stoichiometry
physical entity: TTP
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r2 149
type: Stoichiometry
physical entity: D-glucose-1-phosphate
stoichiometric coefficient: 1.0

Caenorhabditis briggsae
type: BioSource
xref: ncbitaxon 6238 7

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot Q9HT00 123
organism: Halobacterium salinarum

ncbitaxon 6238 7
type: UnificationXref
id: 6238
db: ncbitaxon

dTDP-D-glucose 4,6-dehydratase
type: ProteinReference
xref: uniprot A0A3Q1LGU2 4
organism: Bos taurus

PARTICIPANT STOICHIOMETRY r6 164
type: Stoichiometry
physical entity: glutamine
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r6 165
type: Stoichiometry
physical entity: fructose-6-phosphate
stoichiometric coefficient: 1.0

Caenorhabditis elegans
type: BioSource
xref: ncbitaxon 6239 24

uniprot Q8CJX6 137
type: UnificationXref
id: Q8CJX6
db: uniprot

uniprot Q9RYF1 68
type: UnificationXref
id: Q9RYF1
db: uniprot

uniprot Q8RG65 119
type: UnificationXref
id: Q8RG65
db: uniprot

Protein CBG03656
type: ProteinReference
xref: uniprot A8WVJ0 6
organism: Caenorhabditis briggsae

glutamine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ncbitaxon 10090 41
type: UnificationXref
id: 10090
db: ncbitaxon

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__UDP_galactose-RIGHT__UDP_D_galacto_1,4_furanose-_r1
controller: UDP-galacto-pyranose mutase

dTDP-glucose 4,6-dehydratase
type: ProteinReference
xref: uniprot P39630 21
organism: Bacillus subtilis

Fructose-6-phosphate aminotransferase
type: Protein
entity reference: Fructose-6-phosphate aminotransferase
comment: SPECIES_TYPE=PROTEIN

uniprot H2R176 91
type: UnificationXref
id: H2R176
db: uniprot

Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM2
type: ProteinReference
xref: uniprot Q9LPG6 46
organism: Arabidopsis thaliana

uniprot Q8R6A7 2
type: UnificationXref
id: Q8R6A7
db: uniprot

uniprot F7CBS8 88
type: UnificationXref
id: F7CBS8
db: uniprot

uniprot F7GN87 90
type: UnificationXref
id: F7GN87
db: uniprot

ncbitaxon 188937 37
type: UnificationXref
id: 188937
db: ncbitaxon

Putative glutamine--fructose-6-phosphate aminotransferase [isomerizing]
type: ProteinReference
xref: uniprot A2P2R3 80
organism: Saccharomyces cerevisiae

NADPH
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

UDP-D-galacto-1,4-furanose
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot F7CQ20 13
type: UnificationXref
id: F7CQ20
db: uniprot

uniprot P47856 100
type: UnificationXref
id: P47856
db: uniprot

Bifunctional protein GlmU
type: ProteinReference
xref: uniprot P14192 71
organism: Bacillus subtilis

NADP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Pseudomonas aeruginosa
type: BioSource
xref: ncbitaxon 208964 76

GFPT2 isoform 1
type: ProteinReference
xref: uniprot K7C6M2 92
organism: Pan troglodytes

uniprot Q9RZB2 63
type: UnificationXref
id: Q9RZB2
db: uniprot

ncbitaxon 224308 22
type: UnificationXref
id: 224308
db: ncbitaxon

dTDP-D-glucose 4,6-dehydratase
type: ProteinReference
xref: uniprot Q8VDR7 40
organism: Mus musculus

uniprot Q8RHM3 74
type: UnificationXref
id: Q8RHM3
db: uniprot

uniprot P82808 104
type: UnificationXref
id: P82808
db: uniprot

Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM1
type: ProteinReference
xref: uniprot Q9SYM5 52
organism: Arabidopsis thaliana