ncbitaxon 9598 15
type: UnificationXref
id: 9598
db: ncbitaxon

uniprot Q6PH57 471
type: UnificationXref
id: Q6PH57
db: uniprot

uniprot J9P702 391
type: UnificationXref
id: J9P702
db: uniprot

Neuronal synaptobrevin, isoform J
type: ProteinReference
xref: uniprot M9PE71 182
xref: PTHR45701:SF3
organism: Drosophila melanogaster

PTHR24356:SF303
type: RelationshipXref
id: PTHR24356:SF303
db: PANTHER Family
relationship type: By Homology

Complex (GTP/G-Protein)
type: Complex
component stoichiometry: G Protein s2 sa2 STOICHIOMETRY ID COMPLEX
component stoichiometry: GTP s1 sa1 STOICHIOMETRY ID COMPLEX
component: GTP
component: G-Protein
feature: ACTIVE 146
feature: COMPLEX BINDING FEATURE s24 a30 488
feature: COMPLEX BINDING FEATURE s24 a30 490
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8

uniprot A0A2J8QDF6 20
type: UnificationXref
id: A0A2J8QDF6
db: uniprot

uniprot Q9VXH3 143
type: UnificationXref
id: Q9VXH3
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q5ZJ03 460
organism: Gallus gallus

uniprot P23625 405
type: UnificationXref
id: P23625
db: uniprot

uniprot Q0VFC4 443
type: UnificationXref
id: Q0VFC4
db: uniprot

PTHR24356:SF170
type: RelationshipXref
id: PTHR24356:SF170
db: PANTHER Family
relationship type: By Homology

Syntaxin-3
type: ProteinReference
xref: PTHR19957:SF34
xref: uniprot Q64704 220
organism: Mus musculus

uniprot F6XHP0 357
type: UnificationXref
id: F6XHP0
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot A4IFL6 318
organism: Bos taurus

uniprot Q92356 225
type: UnificationXref
id: Q92356
db: uniprot

ncbitaxon 6945 324
type: UnificationXref
id: 6945
db: ncbitaxon

uniprot F7CTP1 366
type: UnificationXref
id: F7CTP1
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
type: ProteinReference
xref: uniprot P63212 435
organism: Bos taurus

uniprot F6VUT7 170
type: UnificationXref
id: F6VUT7
db: uniprot

Protein kinase C
type: ProteinReference
xref: uniprot A8WR64 244
xref: PTHR24356:SF347
organism: Caenorhabditis briggsae

uniprot P50153 420
type: UnificationXref
id: P50153
db: uniprot

Mus musculus
type: BioSource
xref: ncbitaxon 10090 26

Uncharacterized protein
type: ProteinReference
xref: PTHR45701:SF6
xref: uniprot F6XYX9 171
organism: Monodelphis domestica

PTHR24356:SF181
type: RelationshipXref
id: PTHR24356:SF181
db: PANTHER Family
relationship type: By Homology

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot A8X1E0 27
organism: Caenorhabditis briggsae

Protein kinase C-like 3
type: ProteinReference
xref: PTHR24356:SF303
xref: uniprot Q19266 302
organism: Caenorhabditis elegans

Guanine nucleotide-binding protein (G protein), alpha 11b (Gq class)
type: ProteinReference
xref: PTHR10218:SF328
xref: uniprot Q5RKP9 458
organism: Danio rerio

uniprot O95837 398
type: UnificationXref
id: O95837
db: uniprot

uniprot F7ES96 372
type: UnificationXref
id: F7ES96
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
type: ProteinReference
xref: uniprot P62879 430
organism: Homo sapiens

PTHR19305:SF14
type: RelationshipXref
id: PTHR19305:SF14
db: PANTHER Family
relationship type: By Homology

uniprot P05126 271
type: UnificationXref
id: P05126
db: uniprot

Oxytocin receptor mediated signaling pathway
type: Pathway
pathway component: DISSOCIATION_LEFT__PIP2-RIGHT__IP3-_DAG-_re6
pathway component: TRANSPORT_LEFT__Oxytocin-RIGHT__Oxytocin-_re12
pathway component: TRANSPORT_LEFT__Oxytocin-RIGHT__Oxytocin-_re25
pathway component: TRANSPORT_LEFT__Ca2_PLUS_-RIGHT__Ca2_PLUS_-_re17
pathway component: STATE_TRANSITION_LEFT__PLC_beta-RIGHT__PLC_beta-_re19
pathway component: STATE_TRANSITION_LEFT__PKC-RIGHT__PKC-_re8
pathway component: DISSOCIATION_LEFT__Complex__Oxytocin_Oxytocin_Receptor__G_Protein_GDP_-_GTP-RIGHT__Complex__Oxytocin_Oxytocin_Receptor_-_Complex__GTP_G_Protein_-_GDP-_re24
pathway component: TRIGGER
pathway component: STATE_TRANSITION_LEFT__Ca2_PLUS__channel-RIGHT__Ca2_PLUS__channel-_re16
pathway component: HETERODIMER_ASSOCIATION_LEFT__Complex__Oxytocin_Receptor_G_Protein__GDP_-_Oxytocin-RIGHT__Complex__Oxytocin_Oxytocin_Receptor__G_Protein_GDP_-_re23
xref: PANTHER Pathway P04391 1
comment: MODEL_NOTES=Panther Pathway: P04391 http://www.oxytocin.org/oxy/receptorsystem.html

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
type: ProteinReference
xref: uniprot P62874 429
organism: Mus musculus

uniprot F6TQN3 54
type: UnificationXref
id: F6TQN3
db: uniprot

uniprot P62880 431
type: UnificationXref
id: P62880
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
type: ProteinReference
xref: uniprot P62872 427
organism: Canis lupus familiaris

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
type: ProteinReference
xref: uniprot P62873 428
organism: Homo sapiens

PTHR24356:SF192
type: RelationshipXref
id: PTHR24356:SF192
db: PANTHER Family
relationship type: By Homology

Guanine nucleotide-binding protein subunit beta-5
type: ProteinReference
xref: uniprot P62881 432
organism: Mus musculus

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
type: ProteinReference
xref: uniprot P62880 431
organism: Mus musculus

uniprot P68404 292
type: UnificationXref
id: P68404
db: uniprot

uniprot Q80SZ7 478
type: UnificationXref
id: Q80SZ7
db: uniprot

Oxytocin Receptor
type: ProteinReference
xref: P04531
comment: ENTITY_REFERENCE_ID_DESC=Oxytocin receptor mediated signaling pathway.PROTEIN.RECEPTOR.Oxytocin Receptor
comment: ENTITY_REFERENCE_NOTES=
comment: ENTITY_REFERENCE_PROTEIN_TYPE=RECEPTOR
member entity reference: Oxytocin receptor
member entity reference: Isotocin receptor-like 2

G-Protein
type: ProteinReference
xref: P04534
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=
comment: ENTITY_REFERENCE_ID_DESC=Oxytocin receptor mediated signaling pathway.PROTEIN.GENERIC.G-Protein
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
member entity reference: Guanine nucleotide-binding protein subunit beta-2
member entity reference: Guanine nucleotide-binding protein subunit gamma
member entity reference: GNB4 protein
member entity reference: Guanine nucleotide-binding protein subunit beta
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
member entity reference: Guanine nucleotide-binding protein subunit alpha-14
member entity reference: Uncharacterized protein
member entity reference: Guanine nucleotide-binding protein beta subunit
member entity reference: Guanine nucleotide binding protein, q polypeptide
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
member entity reference: Guanine nucleotide-binding protein subunit alpha-11
member entity reference: Guanine nucleotide-binding protein subunit beta-5
member entity reference: Guanine nucleotide-binding protein subunit beta-5b
member entity reference: Guanine nucleotide-binding protein subunit beta-5a
member entity reference: G protein subunit beta 5
member entity reference: Gbeta5
member entity reference: Guanine nucleotide binding protein (G protein), beta polypeptide 3, like
member entity reference: Guanine nucleotide-binding protein subunit beta-1
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
member entity reference: G protein subunit beta 4
member entity reference: Guanine nucleotide-binding protein (G protein), alpha 14
member entity reference: Guanine nucleotide binding protein, beta 3
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
member entity reference: Gnb3 protein
member entity reference: Guanine nucleotide-binding protein (G protein), beta 5
member entity reference: EGL-30
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
member entity reference: Guanine nucleotide-binding protein G(q) subunit alpha
member entity reference: AGAP005913-PA
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
member entity reference: G protein subunit beta 3
member entity reference: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12

uniprot Q8K4D7 129
type: UnificationXref
id: Q8K4D7
db: uniprot

uniprot Q61016 462
type: UnificationXref
id: Q61016
db: uniprot

uniprot P62871 426
type: UnificationXref
id: P62871
db: uniprot

Synaptosomal-associated protein 29
type: ProteinReference
xref: PTHR19305:SF9
xref: uniprot F6UFJ7 168
organism: Macaca mulatta

PTHR10218:SF316
type: RelationshipXref
id: PTHR10218:SF316
db: PANTHER Family
relationship type: By Homology

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot Q6Z3Y9 116
organism: Oryza sativa

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
type: ProteinReference
xref: uniprot Q01970 98
xref: PTHR10336:SF11
organism: Homo sapiens

uniprot P62881 432
type: UnificationXref
id: P62881
db: uniprot

PTHR24356:SF193
type: RelationshipXref
id: PTHR24356:SF193
db: PANTHER Family
relationship type: By Homology

uniprot P63027 202
type: UnificationXref
id: P63027
db: uniprot

uniprot P21279 404
type: UnificationXref
id: P21279
db: uniprot

uniprot F7BVQ1 61
type: UnificationXref
id: F7BVQ1
db: uniprot

uniprot A0A2I3TRC4 314
type: UnificationXref
id: A0A2I3TRC4
db: uniprot

Neurospora crassa
type: BioSource
xref: ncbitaxon 367110 121

uniprot H2QDQ1 268
type: UnificationXref
id: H2QDQ1
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
type: ProteinReference
xref: uniprot P62871 426
organism: Bos taurus

uniprot Q01970 98
type: UnificationXref
id: Q01970
db: uniprot

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot F6ZC55 59
organism: Monodelphis domestica

PTHR10218:SF328
type: RelationshipXref
id: PTHR10218:SF328
db: PANTHER Family
relationship type: By Homology

PTHR10218:SF329
type: RelationshipXref
id: PTHR10218:SF329
db: PANTHER Family
relationship type: By Homology

PIP2
type: SmallMolecule
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot E1BW98 330
type: UnificationXref
id: E1BW98
db: uniprot

PTHR24356:SF347
type: RelationshipXref
id: PTHR24356:SF347
db: PANTHER Family
relationship type: By Homology

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
type: ProteinReference
xref: uniprot F7CTP1 366
organism: Macaca mulatta

Phosphoinositide phospholipase C
type: ProteinReference
xref: PTHR10336:SF29
xref: uniprot A0A1D5QXV8 12
organism: Macaca mulatta

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot F1Q376 44
organism: Canis lupus familiaris

Synaptosomal-associated protein 25
type: ProteinReference
xref: PTHR19305:SF5
xref: uniprot P60879 197
organism: Mus musculus

uniprot F7DVL1 262
type: UnificationXref
id: F7DVL1
db: uniprot

Synaptosomal-associated protein 25
type: ProteinReference
xref: uniprot P60878 196
xref: PTHR19305:SF5
organism: Gallus gallus

uniprot Q62077 112
type: UnificationXref
id: Q62077
db: uniprot

Putative synaptobrevin homologue SNC1/2 (Eurofung)
type: ProteinReference
xref: uniprot Q5ASG1 214
organism: Emericella nidulans

IP3
type: SmallMolecule
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Guanine nucleotide binding protein, beta 3
type: ProteinReference
xref: uniprot Q5XGD8 459
organism: Xenopus tropicalis

Synaptosomal-associated protein 25
type: ProteinReference
xref: PTHR19305:SF5
xref: uniprot P60877 195
organism: Macaca mulatta

Pan troglodytes
type: BioSource
xref: ncbitaxon 9598 15

Synaptosomal-associated protein 25
type: ProteinReference
xref: uniprot P60880 198
xref: PTHR19305:SF5
organism: Homo sapiens

uniprot P38409 414
type: UnificationXref
id: P38409
db: uniprot

Phosphoinositide phospholipase C
type: ProteinReference
xref: PTHR10336:SF31
xref: uniprot A0A2I3RV12 16
organism: Pan troglodytes

Vesicle-associated membrane protein 3
type: ProteinReference
xref: PTHR45701:SF6
xref: uniprot Q2KJD2 212
organism: Bos taurus

ncbitaxon 5786 342
type: UnificationXref
id: 5786
db: ncbitaxon

uniprot F7BB02 364
type: UnificationXref
id: F7BB02
db: uniprot

Protein kinase C-like 1B
type: ProteinReference
xref: uniprot P34885 288
xref: PTHR24356:SF240
organism: Caenorhabditis elegans

uniprot P11017 399
type: UnificationXref
id: P11017
db: uniprot

uniprot Q62711 114
type: UnificationXref
id: Q62711
db: uniprot

ncbitaxon 6238 28
type: UnificationXref
id: 6238
db: ncbitaxon

Vesicle-associated membrane protein 2
type: ProteinReference
xref: uniprot P63044 203
xref: PTHR45701:SF5
organism: Mus musculus

Vesicle-associated membrane protein 2
type: ProteinReference
xref: uniprot P63045 204
xref: PTHR45701:SF5
organism: Rattus norvegicus

uniprot P63077 433
type: UnificationXref
id: P63077
db: uniprot

DAG
type: SmallMolecule
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q02956 297
type: UnificationXref
id: Q02956
db: uniprot

uniprot K7C8Z4 77
type: UnificationXref
id: K7C8Z4
db: uniprot

Synaptobrevin-1
type: ProteinReference
xref: uniprot O02495 184
xref: PTHR45701:SF3
organism: Caenorhabditis elegans

uniprot F7G1K7 375
type: UnificationXref
id: F7G1K7
db: uniprot

Guanine nucleotide-binding protein subunit beta-5a
type: ProteinReference
xref: uniprot A1L271 317
organism: Danio rerio

Uncharacterized protein
type: ProteinReference
xref: uniprot C3ZSF0 326
organism: Branchiostoma floridae

eco ECO:0000250 6
type: UnificationXref
id: ECO:0000250
db: eco

uniprot F1NG47 253
type: UnificationXref
id: F1NG47
db: uniprot

Protein kinase C delta type
type: ProteinReference
xref: PTHR24356:SF365
xref: uniprot Q7ZUC5 310
organism: Danio rerio

G protein subunit alpha 14
type: ProteinReference
xref: uniprot A0A2I3TRC4 314
xref: PTHR10218:SF213
organism: Pan troglodytes

uniprot Q9SD96 231
type: UnificationXref
id: Q9SD96
db: uniprot

uniprot Q62442 218
type: UnificationXref
id: Q62442
db: uniprot

Vesicle-associated membrane protein 8 (Endobrevin)
type: ProteinReference
xref: PTHR45701:SF7
xref: uniprot Q7ZUC1 224
organism: Danio rerio

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4
type: ProteinReference
xref: PTHR10336:SF106
xref: uniprot Q9QW07 141
organism: Rattus norvegicus

PTHR24356:SF159
type: RelationshipXref
id: PTHR24356:SF159
db: PANTHER Family
relationship type: By Homology

uniprot Q6DF43 465
type: UnificationXref
id: Q6DF43
db: uniprot

PTHR24356:SF158
type: RelationshipXref
id: PTHR24356:SF158
db: PANTHER Family
relationship type: By Homology

Vesicle-associated membrane protein 2
type: ProteinReference
xref: uniprot P63027 202
xref: PTHR45701:SF5
organism: Homo sapiens

Vesicle-associated membrane protein 2
type: ProteinReference
xref: uniprot P63026 201
xref: PTHR45701:SF5
organism: Bos taurus

uniprot Q05513 299
type: UnificationXref
id: Q05513
db: uniprot

PTHR24356:SF365
type: RelationshipXref
id: PTHR24356:SF365
db: PANTHER Family
relationship type: By Homology

Oxytocin receptor
type: ProteinReference
xref: uniprot P56449 150
xref: PTHR24241:SF89
organism: Bos taurus

Putative protein kinase C delta type homolog
type: ProteinReference
xref: uniprot P83099 293
xref: PTHR24356:SF347
organism: Drosophila melanogaster

Vesicle-associated membrane protein 3
type: ProteinReference
xref: PTHR45701:SF6
xref: uniprot P63024 199
organism: Mus musculus

Vesicle-associated membrane protein 3
type: ProteinReference
xref: PTHR45701:SF6
xref: uniprot P63025 200
organism: Rattus norvegicus

uniprot Q8CIH5 124
type: UnificationXref
id: Q8CIH5
db: uniprot

Protein kinase C
type: ProteinReference
xref: uniprot F6RA79 256
xref: PTHR24356:SF193
organism: Monodelphis domestica

SNARE COMPLEX
type: Protein
entity reference: SNARE COMPLEX
cellular location: vesicle
comment: SPECIES_TYPE=PROTEIN

G protein subunit beta 1
type: ProteinReference
xref: uniprot F6PGC8 349
organism: Ornithorhynchus anatinus

uniprot P54313 424
type: UnificationXref
id: P54313
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma
type: ProteinReference
xref: uniprot A8XTZ1 30
organism: Caenorhabditis briggsae

uniprot F6Z8A1 57
type: UnificationXref
id: F6Z8A1
db: uniprot

PTHR24356:SF162
type: RelationshipXref
id: PTHR24356:SF162
db: PANTHER Family
relationship type: By Homology

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot E2R9G5 334
organism: Canis lupus familiaris

Vesicle-associated membrane protein 8
type: ProteinReference
xref: PTHR45701:SF7
xref: uniprot O70404 188
organism: Mus musculus

Guanine nucleotide-binding protein subunit beta-5
type: ProteinReference
xref: uniprot O14775 396
organism: Homo sapiens

VAMP2 isoform 3
type: ProteinReference
xref: uniprot H2RCB8 181
xref: PTHR45701:SF5
organism: Pan troglodytes

uniprot A5PKD6 320
type: UnificationXref
id: A5PKD6
db: uniprot

Vesicle associated membrane protein 8
type: ProteinReference
xref: PTHR45701:SF7
xref: uniprot F6Z5I2 173
organism: Monodelphis domestica

PLC beta
type: Protein
entity reference: PLC beta
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=PROTEIN

uniprot E9FUX0 338
type: UnificationXref
id: E9FUX0
db: uniprot

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot Q21754 104
organism: Caenorhabditis elegans

uniprot F6V461 354
type: UnificationXref
id: F6V461
db: uniprot

uniprot Q7ZUC5 310
type: UnificationXref
id: Q7ZUC5
db: uniprot

G protein subunit beta 4
type: ProteinReference
xref: uniprot E2R2S8 333
organism: Canis lupus familiaris

uniprot P23763 191
type: UnificationXref
id: P23763
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot E2R2S3 332
organism: Canis lupus familiaris

uniprot F6PVT7 350
type: UnificationXref
id: F6PVT7
db: uniprot

uniprot Q3KRE3 450
type: UnificationXref
id: Q3KRE3
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1
type: ProteinReference
xref: PTHR10336:SF51
xref: uniprot Q4KWH5 110
organism: Mus musculus

uniprot P33328 193
type: UnificationXref
id: P33328
db: uniprot

uniprot H9ERR5 72
type: UnificationXref
id: H9ERR5
db: uniprot

MODULATION
type: RelationshipTypeVocabulary

uniprot P63024 199
type: UnificationXref
id: P63024
db: uniprot

uniprot C3ZSF0 326
type: UnificationXref
id: C3ZSF0
db: uniprot

uniprot Q9P212 140
type: UnificationXref
id: Q9P212
db: uniprot

PTHR10336:SF80
type: RelationshipXref
id: PTHR10336:SF80
db: PANTHER Family
relationship type: By Homology

Protein kinase C iota type
type: ProteinReference
xref: PTHR24356:SF214
xref: uniprot Q62074 304
organism: Mus musculus

ncbitaxon 9258 56
type: UnificationXref
id: 9258
db: ncbitaxon

Guanine nucleotide-binding protein subunit alpha-11
type: ProteinReference
xref: PTHR10218:SF328
xref: uniprot Q9JID2 483
organism: Rattus norvegicus

Macaca mulatta
type: BioSource
xref: ncbitaxon 9544 9

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
type: ProteinReference
xref: PTHR10336:SF173
xref: uniprot Q62077 112
organism: Mus musculus

G protein subunit alpha 14
type: ProteinReference
xref: uniprot F7G1U7 376
xref: PTHR10218:SF213
organism: Monodelphis domestica

PTHR10336:SF106
type: RelationshipXref
id: PTHR10336:SF106
db: PANTHER Family
relationship type: By Homology

uniprot F7BYI4 261
type: UnificationXref
id: F7BYI4
db: uniprot

uniprot A8X8S6 161
type: UnificationXref
id: A8X8S6
db: uniprot

Oxytocin receptor
type: ProteinReference
xref: PTHR24241:SF89
xref: uniprot P30559 149
organism: Homo sapiens

uniprot Q00722 97
type: UnificationXref
id: Q00722
db: uniprot

uniprot P41743 289
type: UnificationXref
id: P41743
db: uniprot

uniprot Q39032 106
type: UnificationXref
id: Q39032
db: uniprot

uniprot Q5BJ11 453
type: UnificationXref
id: Q5BJ11
db: uniprot

uniprot P29829 408
type: UnificationXref
id: P29829
db: uniprot

uniprot Q62074 304
type: UnificationXref
id: Q62074
db: uniprot

uniprot Q63666 219
type: UnificationXref
id: Q63666
db: uniprot

Synaptosomal-associated protein 29
type: ProteinReference
xref: PTHR19305:SF9
xref: uniprot O95721 189
organism: Homo sapiens

uniprot H2Q1D9 385
type: UnificationXref
id: H2Q1D9
db: uniprot

uniprot Q9ERB0 227
type: UnificationXref
id: Q9ERB0
db: uniprot

PTHR10336:SF51
type: RelationshipXref
id: PTHR10336:SF51
db: PANTHER Family
relationship type: By Homology

Oxytocin receptor
type: ProteinReference
xref: PTHR24241:SF89
xref: uniprot P56494 151
organism: Macaca mulatta

uniprot P90980 294
type: UnificationXref
id: P90980
db: uniprot

Protein kinase C iota type
type: ProteinReference
xref: PTHR24356:SF214
xref: uniprot P41743 289
organism: Homo sapiens

DISSOCIATION
type: RelationshipTypeVocabulary

uniprot A1L271 317
type: UnificationXref
id: A1L271
db: uniprot

uniprot F6UBJ8 167
type: UnificationXref
id: F6UBJ8
db: uniprot

uniprot O89040 78
type: UnificationXref
id: O89040
db: uniprot

GO GO:0005783 2
type: UnificationXref
id: GO:0005783
db: GO

Protein kinase C epsilon type
type: ProteinReference
xref: uniprot K7CBH8 270
xref: PTHR24356:SF159
organism: Pan troglodytes

uniprot Q8K4S1 130
type: UnificationXref
id: Q8K4S1
db: uniprot

uniprot A0A3Q1MSP9 241
type: UnificationXref
id: A0A3Q1MSP9
db: uniprot

PARTICIPANT STOICHIOMETRY re25 516
type: Stoichiometry
physical entity: Oxytocin
stoichiometric coefficient: 1.0

uniprot Q28H40 449
type: UnificationXref
id: Q28H40
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
type: ProteinReference
xref: uniprot P50150 418
organism: Homo sapiens

PTHR24356:SF390
type: RelationshipXref
id: PTHR24356:SF390
db: PANTHER Family
relationship type: By Homology

PARTICIPANT STOICHIOMETRY re25 515
type: Stoichiometry
physical entity: Oxytocin
stoichiometric coefficient: 1.0

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
type: ProteinReference
xref: uniprot P50151 419
organism: Homo sapiens

uniprot Q15111 101
type: UnificationXref
id: Q15111
db: uniprot

uniprot F5HMB9 48
type: UnificationXref
id: F5HMB9
db: uniprot

uniprot F1PRG8 164
type: UnificationXref
id: F1PRG8
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
type: ProteinReference
xref: uniprot P50154 421
organism: Bos taurus

Uncharacterized protein
type: ProteinReference
xref: PTHR19957:SF34
xref: uniprot A0A3Q1LYB4 158
organism: Bos taurus

uniprot Q7QCP8 307
type: UnificationXref
id: Q7QCP8
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
type: ProteinReference
xref: uniprot P50153 420
organism: Mus musculus

Guanine nucleotide-binding protein G(q) subunit alpha
type: ProteinReference
xref: PTHR10218:SF316
xref: uniprot P50148 417
organism: Homo sapiens

PARTICIPANT STOICHIOMETRY re19 526
type: Stoichiometry
physical entity: PLC beta
stoichiometric coefficient: 1.0

Uncharacterized protein
type: ProteinReference
xref: PTHR19957:SF34
xref: uniprot A0A1D5QDW1 154
organism: Macaca mulatta

PARTICIPANT STOICHIOMETRY re19 525
type: Stoichiometry
physical entity: PLC beta
stoichiometric coefficient: 1.0

mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
type: CellularLocationVocabulary
comment: mammary cells, uterus, also some brain cells (entry of Ca2+ does not cause muscle contraction in neurons)

uniprot D3ZLD6 328
type: UnificationXref
id: D3ZLD6
db: uniprot

ncbitaxon 559292 92
type: UnificationXref
id: 559292
db: ncbitaxon

Uncharacterized protein
type: ProteinReference
xref: PTHR19957:SF34
xref: uniprot F6SED9 166
organism: Monodelphis domestica

uniprot K7E376 394
type: UnificationXref
id: K7E376
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR10336:SF51
xref: uniprot F7GU82 64
organism: Macaca mulatta

ncbitaxon 9913 22
type: UnificationXref
id: 9913
db: ncbitaxon

Protein kinase C
type: ProteinReference
xref: uniprot F7HC75 265
xref: PTHR24356:SF181
organism: Macaca mulatta

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot H2QJ75 68
organism: Pan troglodytes

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot F1M324 36
organism: Rattus norvegicus

PTHR10336:SF33
type: RelationshipXref
id: PTHR10336:SF33
db: PANTHER Family
relationship type: By Homology

uniprot K7AE17 393
type: UnificationXref
id: K7AE17
db: uniprot

PTHR10336:SF31
type: RelationshipXref
id: PTHR10336:SF31
db: PANTHER Family
relationship type: By Homology

uniprot A0A1D5QG31 313
type: UnificationXref
id: A0A1D5QG31
db: uniprot

Inactive phospholipase C-like protein 2
type: ProteinReference
xref: uniprot Q8K394 127
organism: Mus musculus

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot F7D5G3 62
organism: Ornithorhynchus anatinus

ncbitaxon 39947 117
type: UnificationXref
id: 39947
db: ncbitaxon

uniprot F6ZKL2 60
type: UnificationXref
id: F6ZKL2
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
type: ProteinReference
xref: uniprot A3KGF7 25
xref: PTHR10336:SF10
organism: Mus musculus

G-Protein
type: Protein
entity reference: G-Protein
feature: COMPLEX PARTICIPANT BINDING FEATURE s10 sa8 507
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=PROTEIN

uniprot F7G3J2 377
type: UnificationXref
id: F7G3J2
db: uniprot

Oxytocin receptor
type: ProteinReference
xref: uniprot P70536 152
xref: PTHR24241:SF89
organism: Rattus norvegicus

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
type: ProteinReference
xref: PTHR10336:SF106
xref: uniprot A0A3Q2U0G2 23
organism: Gallus gallus

uniprot F5HH30 348
type: UnificationXref
id: F5HH30
db: uniprot

ncbitaxon 367110 121
type: UnificationXref
id: 367110
db: ncbitaxon

Uncharacterized protein
type: ProteinReference
xref: PTHR45701:SF6
xref: uniprot F6YMH2 172
organism: Macaca mulatta

uniprot E2RHY4 336
type: UnificationXref
id: E2RHY4
db: uniprot

uniprot A0A2R8QJ48 239
type: UnificationXref
id: A0A2R8QJ48
db: uniprot

PTHR10336:SF25
type: RelationshipXref
id: PTHR10336:SF25
db: PANTHER Family
relationship type: By Homology

STATE_TRANSITION
type: RelationshipTypeVocabulary

uniprot P24723 285
type: UnificationXref
id: P24723
db: uniprot

PTHR10336:SF29
type: RelationshipXref
id: PTHR10336:SF29
db: PANTHER Family
relationship type: By Homology

uniprot P62879 430
type: UnificationXref
id: P62879
db: uniprot

uniprot Q7Q6D3 475
type: UnificationXref
id: Q7Q6D3
db: uniprot

uniprot Q28HP6 211
type: UnificationXref
id: Q28HP6
db: uniprot

Vesicle-associated membrane protein 8
type: ProteinReference
xref: PTHR45701:SF7
xref: uniprot Q9BV40 226
organism: Homo sapiens

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot G3V6P8 381
organism: Rattus norvegicus

uniprot F2Z3T8 347
type: UnificationXref
id: F2Z3T8
db: uniprot

uniprot P83099 293
type: UnificationXref
id: P83099
db: uniprot

uniprot A0A1D5R8E9 13
type: UnificationXref
id: A0A1D5R8E9
db: uniprot

uniprot F1Q376 44
type: UnificationXref
id: F1Q376
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F7A943 174
xref: PTHR45701:SF5
organism: Monodelphis domestica

Soluble NSF attachment protein 29
type: ProteinReference
xref: PTHR19305:SF9
xref: uniprot P83351 205
organism: Caenorhabditis elegans

uniprot H2Q9G5 387
type: UnificationXref
id: H2Q9G5
db: uniprot

Protein kinase C eta type
type: ProteinReference
xref: PTHR24356:SF192
xref: uniprot F1MY82 252
organism: Bos taurus

uniprot P56494 151
type: UnificationXref
id: P56494
db: uniprot

G protein subunit beta 5
type: ProteinReference
xref: uniprot H2Q9G5 387
organism: Pan troglodytes

uniprot A0A2I3RQJ8 237
type: UnificationXref
id: A0A2I3RQJ8
db: uniprot

Protein kinase C
type: ProteinReference
xref: PTHR24356:SF193
xref: uniprot H2QDQ1 268
organism: Pan troglodytes

PTHR10336:SF11
type: RelationshipXref
id: PTHR10336:SF11
db: PANTHER Family
relationship type: By Homology

PTHR10336:SF12
type: RelationshipXref
id: PTHR10336:SF12
db: PANTHER Family
relationship type: By Homology

PTHR10336:SF10
type: RelationshipXref
id: PTHR10336:SF10
db: PANTHER Family
relationship type: By Homology

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma
type: ProteinReference
xref: PTHR10336:SF25
xref: uniprot A0A2I3SHP7 18
organism: Pan troglodytes

uniprot P10687 81
type: UnificationXref
id: P10687
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
type: ProteinReference
xref: PTHR10336:SF173
xref: uniprot P19174 89
organism: Homo sapiens

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
type: ProteinReference
xref: uniprot P63219 442
organism: Rattus norvegicus

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
type: ProteinReference
xref: uniprot P63218 441
organism: Homo sapiens

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
type: ProteinReference
xref: uniprot P63217 440
organism: Bos taurus

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
type: ProteinReference
xref: uniprot P63216 439
organism: Mus musculus

uniprot P63219 442
type: UnificationXref
id: P63219
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
type: ProteinReference
xref: uniprot P63215 438
organism: Homo sapiens

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
type: ProteinReference
xref: uniprot P63214 437
organism: Bos taurus

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
type: ProteinReference
xref: uniprot P63213 436
organism: Mus musculus

Caenorhabditis briggsae
type: BioSource
xref: ncbitaxon 6238 28

uniprot A3KGF7 25
type: UnificationXref
id: A3KGF7
db: uniprot

uniprot P17252 282
type: UnificationXref
id: P17252
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q15KE4 445
organism: Danio rerio

uniprot F6Y3N2 359
type: UnificationXref
id: F6Y3N2
db: uniprot

Caenorhabditis elegans
type: BioSource
xref: ncbitaxon 6239 66

uniprot P60879 197
type: UnificationXref
id: P60879
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
type: ProteinReference
xref: PTHR10336:SF106
xref: uniprot P13217 85
organism: Drosophila melanogaster

Guanine nucleotide-binding protein subunit beta-2
type: ProteinReference
xref: uniprot P29829 408
organism: Drosophila melanogaster

uniprot Q9Z2P6 235
type: UnificationXref
id: Q9Z2P6
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
type: ProteinReference
xref: uniprot P51432 96
xref: PTHR10336:SF11
organism: Mus musculus

uniprot P52287 422
type: UnificationXref
id: P52287
db: uniprot

uniprot A0A3Q1MMD9 21
type: UnificationXref
id: A0A3Q1MMD9
db: uniprot

PTHR24241:SF89
type: RelationshipXref
id: PTHR24241:SF89
db: PANTHER Family
relationship type: By Homology

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F7F580 373
organism: Macaca mulatta

Phosphoinositide phospholipase C 3
type: ProteinReference
xref: uniprot Q56W08 111
organism: Arabidopsis thaliana

uniprot P09215 276
type: UnificationXref
id: P09215
db: uniprot

PLC beta
type: Protein
entity reference: PLC beta
feature: ACTIVE 146
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=PROTEIN

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
type: ProteinReference
xref: uniprot Q9CXP8 480
organism: Mus musculus

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
type: ProteinReference
xref: uniprot F6ZKL2 60
xref: PTHR10336:SF12
organism: Macaca mulatta

G protein subunit alpha q
type: ProteinReference
xref: PTHR10218:SF316
xref: uniprot E1BA29 329
organism: Bos taurus

uniprot F6YZA3 360
type: UnificationXref
id: F6YZA3
db: uniprot

uniprot E4W699 147
type: UnificationXref
id: E4W699
db: uniprot

Guanine nucleotide-binding protein subunit alpha-11
type: ProteinReference
xref: PTHR10218:SF328
xref: uniprot A0A1D5QG31 313
organism: Macaca mulatta

uniprot F7EG64 263
type: UnificationXref
id: F7EG64
db: uniprot

uniprot P97926 153
type: UnificationXref
id: P97926
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot E2RGI5 335
organism: Canis lupus familiaris

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4
type: ProteinReference
xref: PTHR10336:SF31
xref: uniprot Q62711 114
organism: Rattus norvegicus

Protein kinase C delta type
type: ProteinReference
xref: PTHR24356:SF365
xref: uniprot A0A3Q1MRR6 240
organism: Bos taurus

uniprot Q9VH76 232
type: UnificationXref
id: Q9VH76
db: uniprot

uniprot P36408 412
type: UnificationXref
id: P36408
db: uniprot

uniprot E2R907 163
type: UnificationXref
id: E2R907
db: uniprot

Synaptobrevin
type: ProteinReference
xref: uniprot P18489 190
xref: PTHR45701:SF10
organism: Drosophila melanogaster

Ca2+
type: SmallMolecule
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=ION

TRANSPORT
type: RelationshipTypeVocabulary

SNAP25 homologous protein SNAP29
type: ProteinReference
xref: uniprot Q9SD96 231
organism: Arabidopsis thaliana

Cryptococcus neoformans
type: BioSource
xref: ncbitaxon 214684 457

Sclerotinia sclerotiorum
type: BioSource
xref: ncbitaxon 665079 322

Guanine nucleotide-binding protein subunit beta-1
type: ProteinReference
xref: uniprot P17343 401
organism: Caenorhabditis elegans

Protein kinase C iota type
type: ProteinReference
xref: PTHR24356:SF214
xref: uniprot Q90XF2 311
organism: Danio rerio

uniprot Q6NMA7 115
type: UnificationXref
id: Q6NMA7
db: uniprot

Protein kinase C
type: ProteinReference
xref: PTHR24356:SF192
xref: uniprot F6VT32 257
organism: Xenopus tropicalis

uniprot E2R2S8 333
type: UnificationXref
id: E2R2S8
db: uniprot

uniprot H2QKD0 70
type: UnificationXref
id: H2QKD0
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q3SZ98 451
organism: Bos taurus

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
type: ProteinReference
xref: PTHR10336:SF12
xref: uniprot F6SD46 50
organism: Monodelphis domestica

Synaptosomal-associated protein 25-A
type: ProteinReference
xref: PTHR19305:SF5
xref: uniprot Q5TZ66 217
organism: Danio rerio

uniprot Q7ZUC1 224
type: UnificationXref
id: Q7ZUC1
db: uniprot

G Protein s2 sa2 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: G-Protein
stoichiometric coefficient: 1.0

uniprot F1MY82 252
type: UnificationXref
id: F1MY82
db: uniprot

Synaptosomal-associated protein
type: ProteinReference
xref: PTHR19305:SF14
xref: uniprot A5PEW5 159
organism: Caenorhabditis elegans

uniprot A0A2I3RV12 16
type: UnificationXref
id: A0A2I3RV12
db: uniprot

uniprot P63318 290
type: UnificationXref
id: P63318
db: uniprot

Guanine nucleotide-binding protein (G protein), alpha 11 (Gq class)
type: ProteinReference
xref: uniprot F6THW2 353
xref: PTHR10218:SF328
organism: Xenopus tropicalis

Branchiostoma floridae
type: BioSource
xref: ncbitaxon 7739 327

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F6SSS3 351
organism: Monodelphis domestica

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot H2Q1D9 385
organism: Pan troglodytes

uniprot Q02156 296
type: UnificationXref
id: Q02156
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F6W548 356
organism: Macaca mulatta

uniprot Q7Q042 306
type: UnificationXref
id: Q7Q042
db: uniprot

uniprot Q62688 113
type: UnificationXref
id: Q62688
db: uniprot

uniprot F7G7I9 378
type: UnificationXref
id: F7G7I9
db: uniprot

ISS
type: EvidenceCodeVocabulary
xref: eco ECO:0000250 6

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
type: ProteinReference
xref: uniprot P52287 422
organism: Rattus norvegicus

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
type: ProteinReference
xref: PTHR10336:SF106
xref: uniprot Q91UZ1 132
organism: Mus musculus

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
type: ProteinReference
xref: PTHR10336:SF6
xref: uniprot Q8K4S1 130
organism: Mus musculus

Synaptosomal-associated protein
type: ProteinReference
xref: uniprot F6UBJ8 167
xref: PTHR19305:SF4
organism: Xenopus tropicalis

Synaptobrevin homolog 2
type: ProteinReference
xref: uniprot P33328 193
organism: Saccharomyces cerevisiae

GDP
type: SmallMolecule
feature: COMPLEX PARTICIPANT BINDING FEATURE s6 sa5 497
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=SIMPLE_MOLECULE

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
type: ProteinReference
xref: PTHR10336:SF12
xref: uniprot Q9Z1B3 145
organism: Mus musculus

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
type: ProteinReference
xref: uniprot G5EFI8 67
xref: PTHR10336:SF6
organism: Caenorhabditis elegans

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
type: ProteinReference
xref: uniprot Q00722 97
xref: PTHR10336:SF10
organism: Homo sapiens

uniprot E2RJB3 337
type: UnificationXref
id: E2RJB3
db: uniprot

uniprot Q9QW07 141
type: UnificationXref
id: Q9QW07
db: uniprot

uniprot A8X1E0 27
type: UnificationXref
id: A8X1E0
db: uniprot

uniprot Q5EAP4 454
type: UnificationXref
id: Q5EAP4
db: uniprot

uniprot P56449 150
type: UnificationXref
id: P56449
db: uniprot

uniprot F1PL90 40
type: UnificationXref
id: F1PL90
db: uniprot

Phosphoinositide phospholipase C 5
type: ProteinReference
xref: uniprot Q944C2 134
organism: Arabidopsis thaliana

uniprot H9ZA60 74
type: UnificationXref
id: H9ZA60
db: uniprot

ncbitaxon 214684 457
type: UnificationXref
id: 214684
db: ncbitaxon

Oxytocin Receptor
type: Protein
entity reference: Oxytocin Receptor
feature: COMPLEX PARTICIPANT BINDING FEATURE s9 sa7 505
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=PROTEIN

uniprot P09217 278
type: UnificationXref
id: P09217
db: uniprot

uniprot P70536 152
type: UnificationXref
id: P70536
db: uniprot

Syntaxin-3
type: ProteinReference
xref: PTHR19957:SF34
xref: uniprot Q13277 208
organism: Homo sapiens

Uncharacterized protein
type: ProteinReference
xref: PTHR10218:SF316
xref: uniprot F7G1K7 375
organism: Monodelphis domestica

Protein kinase C iota type
type: ProteinReference
xref: PTHR24356:SF214
xref: uniprot F1M7Y5 250
organism: Rattus norvegicus

Monodelphis domestica
type: BioSource
xref: ncbitaxon 13616 51

uniprot Q9XWB7 144
type: UnificationXref
id: Q9XWB7
db: uniprot

uniprot Q9NQ66 139
type: UnificationXref
id: Q9NQ66
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot K7AE17 393
organism: Pan troglodytes

Ca2+ channel
type: Protein
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=PROTEIN

Protein kinase C
type: ProteinReference
xref: uniprot F1NG47 253
xref: PTHR24356:SF159
organism: Gallus gallus

Uncharacterized protein
type: ProteinReference
xref: uniprot E1BW98 330
organism: Gallus gallus

Protein kinase C epsilon type
type: ProteinReference
xref: PTHR24356:SF159
xref: uniprot F7BIC2 260
organism: Macaca mulatta

uniprot P05771 275
type: UnificationXref
id: P05771
db: uniprot

uniprot Q7PXP3 473
type: UnificationXref
id: Q7PXP3
db: uniprot

Synaptosomal-associated protein
type: ProteinReference
xref: uniprot F6VUT7 170
xref: PTHR19305:SF5
organism: Ornithorhynchus anatinus

Synaptosomal-associated protein 23
type: ProteinReference
xref: PTHR19305:SF4
xref: uniprot O00161 183
organism: Homo sapiens

uniprot P63044 203
type: UnificationXref
id: P63044
db: uniprot

GDP
type: SmallMolecule
feature: COMPLEX PARTICIPANT BINDING FEATURE s11 sa9 509
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Protein kinase C eta type
type: ProteinReference
xref: uniprot E2RGU7 248
xref: PTHR24356:SF192
organism: Canis lupus familiaris

uniprot F7FXA9 374
type: UnificationXref
id: F7FXA9
db: uniprot

Phosphoinositide phospholipase C 4
type: ProteinReference
xref: uniprot Q944C1 133
organism: Arabidopsis thaliana

uniprot F6YMH2 172
type: UnificationXref
id: F6YMH2
db: uniprot

Protein kinase C gamma type
type: ProteinReference
xref: PTHR24356:SF162
xref: uniprot P05129 273
organism: Homo sapiens

Protein kinase C beta type
type: ProteinReference
xref: PTHR24356:SF158
xref: uniprot P05126 271
organism: Bos taurus

uniprot A0A1D5Q3D7 8
type: UnificationXref
id: A0A1D5Q3D7
db: uniprot

Protein kinase C gamma type (Fragment)
type: ProteinReference
xref: PTHR24356:SF162
xref: uniprot P05128 272
organism: Bos taurus

uniprot O95721 189
type: UnificationXref
id: O95721
db: uniprot

uniprot P30677 411
type: UnificationXref
id: P30677
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F7G3J2 377
organism: Monodelphis domestica

GDP s6 sa5 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: GDP
stoichiometric coefficient: 1.0

uniprot F7ASR8 363
type: UnificationXref
id: F7ASR8
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8
type: ProteinReference
xref: PTHR10336:SF106
xref: uniprot G5EBH0 65
organism: Caenorhabditis elegans

Vesicle associated membrane protein 1
type: ProteinReference
xref: uniprot F1PRG8 164
xref: PTHR45701:SF1
organism: Canis lupus familiaris

Protein kinase C alpha type
type: ProteinReference
xref: uniprot P20444 283
xref: PTHR24356:SF193
organism: Mus musculus

Complex (Oxytocin/Oxytocin Receptor/ G-Protein/GDP)
type: Complex
component stoichiometry: Oxytocin s8 sa6 STOICHIOMETRY ID COMPLEX
component stoichiometry: G Protein s10 sa8 STOICHIOMETRY ID COMPLEX
component stoichiometry: Oxytocin Receptor s9 sa7 STOICHIOMETRY ID COMPLEX
component stoichiometry: GDP s11 sa9 STOICHIOMETRY ID COMPLEX
component: Oxytocin Receptor
component: Oxytocin
component: G-Protein
component: GDP
feature: COMPLEX BINDING FEATURE s63 a85 506
feature: COMPLEX BINDING FEATURE s63 a85 504
feature: COMPLEX BINDING FEATURE s63 a85 502
feature: COMPLEX BINDING FEATURE s63 a85 508
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8

uniprot Q6DGZ5 466
type: UnificationXref
id: Q6DGZ5
db: uniprot

uniprot P21278 403
type: UnificationXref
id: P21278
db: uniprot

Synaptosomal-associated protein 29
type: ProteinReference
xref: uniprot Q9ERB0 227
xref: PTHR19305:SF9
organism: Mus musculus

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q6DF43 465
organism: Xenopus tropicalis

Protein kinase C, brain isozyme
type: ProteinReference
xref: uniprot P05130 274
xref: PTHR24356:SF390
organism: Drosophila melanogaster

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma
type: ProteinReference
xref: PTHR10336:SF173
xref: uniprot H2QKD0 70
organism: Pan troglodytes

PARTICIPANT STOICHIOMETRY re17 527
type: Stoichiometry
physical entity: Ca2+
stoichiometric coefficient: 1.0

ncbitaxon 7165 49
type: UnificationXref
id: 7165
db: ncbitaxon

PARTICIPANT STOICHIOMETRY re17 528
type: Stoichiometry
physical entity: Ca2+
stoichiometric coefficient: 1.0

Guanine nucleotide-binding protein subunit beta-4
type: ProteinReference
xref: uniprot Q9HAV0 482
organism: Homo sapiens

Phosphoinositide phospholipase C (Fragment)
type: ProteinReference
xref: uniprot Q7PW25 118
organism: Anopheles gambiae

Complex (Oxytocin/Oxytocin Receptor)
type: Complex
component stoichiometry: Oxytocin Receptor s13 sa11 STOICHIOMETRY ID COMPLEX
component stoichiometry: Oxytocin s12 sa10 STOICHIOMETRY ID COMPLEX
component: Oxytocin Receptor
component: Oxytocin
feature: COMPLEX BINDING FEATURE s65 a89 500
feature: COMPLEX BINDING FEATURE s65 a89 498
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8

Guanine nucleotide-binding protein subunit alpha-14
type: ProteinReference
xref: uniprot P38408 413
xref: PTHR10218:SF213
organism: Bos taurus

Guanine nucleotide-binding protein subunit alpha-11
type: ProteinReference
xref: uniprot P38409 414
xref: PTHR10218:SF328
organism: Bos taurus

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot H9ERR5 72
organism: Macaca mulatta

uniprot F1MDC9 251
type: UnificationXref
id: F1MDC9
db: uniprot

uniprot Q13277 208
type: UnificationXref
id: Q13277
db: uniprot

Guanine nucleotide-binding protein subunit beta
type: ProteinReference
xref: uniprot Q10282 444
organism: Schizosaccharomyces pombe

uniprot P63214 437
type: UnificationXref
id: P63214
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1
type: ProteinReference
xref: uniprot Q86YW0 123
xref: PTHR10336:SF29
organism: Homo sapiens

uniprot Q5BH99 452
type: UnificationXref
id: Q5BH99
db: uniprot

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot Q8IA75 125
organism: Caenorhabditis elegans

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1
type: ProteinReference
xref: uniprot P40977 93
organism: Schizosaccharomyces pombe

uniprot A0A2I3SR38 238
type: UnificationXref
id: A0A2I3SR38
db: uniprot

uniprot P63217 440
type: UnificationXref
id: P63217
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot E2RJB3 337
organism: Canis lupus familiaris

Arabidopsis thaliana
type: BioSource
xref: ncbitaxon 3702 107

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
type: ProteinReference
xref: uniprot A0A2I3T8F7 19
xref: PTHR10336:SF11
organism: Pan troglodytes

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
type: ProteinReference
xref: PTHR10336:SF106
xref: uniprot F5HMB9 48
organism: Anopheles gambiae

uniprot Q15KE4 445
type: UnificationXref
id: Q15KE4
db: uniprot

Guanine nucleotide-binding protein subunit beta
type: ProteinReference
xref: uniprot P18851 402
organism: Saccharomyces cerevisiae

Guanine nucleotide-binding protein subunit beta-5b
type: ProteinReference
xref: uniprot Q6PBY0 470
organism: Danio rerio

uniprot Q02158 99
type: UnificationXref
id: Q02158
db: uniprot

Gbeta5
type: ProteinReference
xref: uniprot Q9W3J1 486
organism: Drosophila melanogaster

PTHR45701:SF6
type: RelationshipXref
id: PTHR45701:SF6
db: PANTHER Family
relationship type: By Homology

uniprot F6SRP9 52
type: UnificationXref
id: F6SRP9
db: uniprot

PTHR45701:SF7
type: RelationshipXref
id: PTHR45701:SF7
db: PANTHER Family
relationship type: By Homology

G protein subunit gamma 5
type: ProteinReference
xref: uniprot H2PZA6 384
organism: Pan troglodytes

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
type: ProteinReference
xref: uniprot Q99JE6 135
xref: PTHR10336:SF11
organism: Rattus norvegicus

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F1PJE5 346
organism: Canis lupus familiaris

PTHR45701:SF5
type: RelationshipXref
id: PTHR45701:SF5
db: PANTHER Family
relationship type: By Homology

uniprot F6SED9 166
type: UnificationXref
id: F6SED9
db: uniprot

PTHR45701:SF3
type: RelationshipXref
id: PTHR45701:SF3
db: PANTHER Family
relationship type: By Homology

uniprot Q7SY24 308
type: UnificationXref
id: Q7SY24
db: uniprot

PTHR45701:SF1
type: RelationshipXref
id: PTHR45701:SF1
db: PANTHER Family
relationship type: By Homology

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
type: ProteinReference
xref: uniprot Q9UK08 485
organism: Homo sapiens

uniprot E2RNP2 249
type: UnificationXref
id: E2RNP2
db: uniprot

Guanine nucleotide-binding protein subunit alpha-11
type: ProteinReference
xref: uniprot P29992 409
xref: PTHR10218:SF328
organism: Homo sapiens

uniprot Q2KJD2 212
type: UnificationXref
id: Q2KJD2
db: uniprot

uniprot E1BH60 32
type: UnificationXref
id: E1BH60
db: uniprot

uniprot Q08849 206
type: UnificationXref
id: Q08849
db: uniprot

uniprot A5PEW5 159
type: UnificationXref
id: A5PEW5
db: uniprot

G protein subunit alpha q
type: ProteinReference
xref: PTHR10218:SF316
xref: uniprot K6ZCJ5 392
organism: Pan troglodytes

Danio rerio
type: BioSource
xref: ncbitaxon 7955 46

uniprot F7A632 259
type: UnificationXref
id: F7A632
db: uniprot

STATE_TRANSITION_LEFT__PLC_beta-RIGHT__PLC_beta-_re19
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY re19 525
participant stoichiometry: PARTICIPANT STOICHIOMETRY re19 526
left: PLC beta
interaction type: STATE_TRANSITION
right: PLC beta

ncbitaxon 9615 34
type: UnificationXref
id: 9615
db: ncbitaxon

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot F1MLS3 38
organism: Bos taurus

TRIGGER
type: Control
xref: TRIGGER
controlled: TRANSPORT_LEFT__Oxytocin-RIGHT__Oxytocin-_re25
control type: ACTIVATION
controller: SNARE COMPLEX

Protein kinase C, eye isozyme
type: ProteinReference
xref: uniprot P13677 279
xref: PTHR24356:SF390
organism: Drosophila melanogaster

Phosphoinositide phospholipase C 1
type: ProteinReference
xref: uniprot Q39032 106
organism: Arabidopsis thaliana

Syntaxin-3
type: ProteinReference
xref: PTHR19957:SF34
xref: uniprot Q08849 206
organism: Rattus norvegicus

Protein kinase C beta type
type: ProteinReference
xref: uniprot Q7SY24 308
xref: PTHR24356:SF158
organism: Danio rerio

Phosphoinositide phospholipase C 2
type: ProteinReference
xref: uniprot Q39033 108
organism: Arabidopsis thaliana

Protein kinase C
type: ProteinReference
xref: PTHR24356:SF240
xref: uniprot P13678 280
organism: Drosophila melanogaster

uniprot Q9BRC7 137
type: UnificationXref
id: Q9BRC7
db: uniprot

G protein subunit beta 2
type: ProteinReference
xref: uniprot A0A2I3TUD1 315
organism: Pan troglodytes

Synaptosomal-associated protein 25
type: ProteinReference
xref: PTHR19305:SF5
xref: uniprot Q17QQ3 210
organism: Bos taurus

G protein subunit alpha 14
type: ProteinReference
xref: uniprot F1NU41 345
xref: PTHR10218:SF213
organism: Gallus gallus

Guanine nucleotide binding protein, q polypeptide
type: ProteinReference
xref: uniprot E9GJ31 340
xref: PTHR10218:SF329
organism: Daphnia pulex

uniprot F7E427 368
type: UnificationXref
id: F7E427
db: uniprot

uniprot F6ZIZ9 361
type: UnificationXref
id: F6ZIZ9
db: uniprot

uniprot H2Q995 179
type: UnificationXref
id: H2Q995
db: uniprot

uniprot Q803H5 477
type: UnificationXref
id: Q803H5
db: uniprot

uniprot F7H6T7 380
type: UnificationXref
id: F7H6T7
db: uniprot

Vesicle-associated membrane protein 2
type: ProteinReference
xref: uniprot Q9N0Y0 229
xref: PTHR45701:SF5
organism: Macaca mulatta

Protein kinase C
type: ProteinReference
xref: uniprot F1MDC9 251
xref: PTHR24351:SF182
organism: Bos taurus

uniprot Q5PU49 303
type: UnificationXref
id: Q5PU49
db: uniprot

Phosphoinositide phospholipase C 9
type: ProteinReference
xref: uniprot Q6NMA7 115
organism: Arabidopsis thaliana

Synaptosomal-associated protein 25
type: ProteinReference
xref: PTHR19305:SF14
xref: uniprot P36975 194
organism: Drosophila melanogaster

Vesicle-associated membrane protein 8
type: ProteinReference
xref: PTHR45701:SF7
xref: uniprot Q3T0Y8 213
organism: Bos taurus

uniprot Q9LMG8 228
type: UnificationXref
id: Q9LMG8
db: uniprot

uniprot P63078 434
type: UnificationXref
id: P63078
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F6YZA3 360
organism: Monodelphis domestica

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot A0A2I3RKF6 14
organism: Pan troglodytes

uniprot A0A1D5QIS2 155
type: UnificationXref
id: A0A1D5QIS2
db: uniprot

Vesicle-associated membrane protein 3
type: ProteinReference
xref: PTHR45701:SF6
xref: uniprot Q15836 209
organism: Homo sapiens

PANTHER Pathway P04391 1
type: UnificationXref
id: P04391
db: PANTHER Pathway

uniprot P54311 423
type: UnificationXref
id: P54311
db: uniprot

uniprot Q22070 105
type: UnificationXref
id: Q22070
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4
type: ProteinReference
xref: PTHR10336:SF31
xref: uniprot Q9BRC7 137
organism: Homo sapiens

uniprot P51432 96
type: UnificationXref
id: P51432
db: uniprot

uniprot A7EDU2 321
type: UnificationXref
id: A7EDU2
db: uniprot

uniprot Q4KWH5 110
type: UnificationXref
id: Q4KWH5
db: uniprot

Synaptosomal-associated protein 25-B
type: ProteinReference
xref: PTHR19305:SF5
xref: uniprot Q6PC54 221
organism: Danio rerio

ncbitaxon 9606 88
type: UnificationXref
id: 9606
db: ncbitaxon

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4
type: ProteinReference
xref: PTHR10336:SF106
xref: uniprot Q15147 102
organism: Homo sapiens

Synaptosomal-associated protein
type: ProteinReference
xref: uniprot O44419 186
xref: PTHR19305:SF14
organism: Strongylocentrotus purpuratus

uniprot P50154 421
type: UnificationXref
id: P50154
db: uniprot

Protein kinase C
type: ProteinReference
xref: uniprot F6XMN6 258
xref: PTHR24356:SF170
organism: Canis lupus familiaris

uniprot Q8R3B1 131
type: UnificationXref
id: Q8R3B1
db: uniprot

Guanine nucleotide binding protein (G protein), beta polypeptide 3, like
type: ProteinReference
xref: uniprot Q6DH55 467
organism: Danio rerio

uniprot G5EGU1 383
type: UnificationXref
id: G5EGU1
db: uniprot

uniprot F6VM87 169
type: UnificationXref
id: F6VM87
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F6TFY2 352
organism: Macaca mulatta

Phosphoinositide phospholipase C 7
type: ProteinReference
xref: uniprot Q9LY51 138
organism: Arabidopsis thaliana

Inactive phospholipase C-like protein 1
type: ProteinReference
xref: uniprot Q15111 101
organism: Homo sapiens

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
type: ProteinReference
xref: PTHR10336:SF12
xref: uniprot K7BA21 76
organism: Pan troglodytes

uniprot Q9LY51 138
type: UnificationXref
id: Q9LY51
db: uniprot

uniprot F1PL99 41
type: UnificationXref
id: F1PL99
db: uniprot

uniprot P51178 95
type: UnificationXref
id: P51178
db: uniprot

Vesicle-associated membrane protein 1
type: ProteinReference
xref: uniprot Q62442 218
xref: PTHR45701:SF1
organism: Mus musculus

Rattus norvegicus
type: BioSource
xref: ncbitaxon 10116 5

uniprot Q9N0Y0 229
type: UnificationXref
id: Q9N0Y0
db: uniprot

uniprot P34722 287
type: UnificationXref
id: P34722
db: uniprot

P04531
type: UnificationXref
id: P04531
db: PANTHER Pathway Component

P04530
type: UnificationXref
id: P04530
db: PANTHER Pathway Component

P04533
type: UnificationXref
id: P04533
db: PANTHER Pathway Component

uniprot M9PE71 182
type: UnificationXref
id: M9PE71
db: uniprot

P04532
type: UnificationXref
id: P04532
db: PANTHER Pathway Component

Oxytocin Receptor s13 sa11 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Oxytocin Receptor
stoichiometric coefficient: 1.0

P04534
type: UnificationXref
id: P04534
db: PANTHER Pathway Component

PTHR10336:SF6
type: RelationshipXref
id: PTHR10336:SF6
db: PANTHER Family
relationship type: By Homology

uniprot Q3SZ98 451
type: UnificationXref
id: Q3SZ98
db: uniprot

uniprot Q8K394 127
type: UnificationXref
id: Q8K394
db: uniprot

Protein kinase C delta type
type: ProteinReference
xref: PTHR24356:SF365
xref: uniprot Q05655 300
organism: Homo sapiens

Daphnia pulex
type: BioSource
xref: ncbitaxon 6669 339

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3
type: ProteinReference
xref: PTHR10336:SF33
xref: uniprot Q8K2J0 126
organism: Mus musculus

uniprot H2QLA1 180
type: UnificationXref
id: H2QLA1
db: uniprot

uniprot Q61011 461
type: UnificationXref
id: Q61011
db: uniprot

Protein kinase C
type: ProteinReference
xref: uniprot E1BWA3 247
xref: PTHR24356:SF214
organism: Gallus gallus

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
type: ProteinReference
xref: uniprot P63078 434
organism: Mus musculus

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
type: ProteinReference
xref: uniprot P63077 433
organism: Rattus norvegicus

uniprot F6RA79 256
type: UnificationXref
id: F6RA79
db: uniprot

ncbitaxon 9031 24
type: UnificationXref
id: 9031
db: ncbitaxon

muscle contraction
type: Pathway

uniprot Q9W3J1 486
type: UnificationXref
id: Q9W3J1
db: uniprot

uniprot F6VT32 257
type: UnificationXref
id: F6VT32
db: uniprot

LD03592p
type: ProteinReference
xref: uniprot Q9W1I8 233
xref: PTHR19305:SF9
organism: Drosophila melanogaster

ncbitaxon 10116 5
type: UnificationXref
id: 10116
db: ncbitaxon

uniprot P13678 280
type: UnificationXref
id: P13678
db: uniprot

uniprot Q66JF0 464
type: UnificationXref
id: Q66JF0
db: uniprot

uniprot E9GJ31 340
type: UnificationXref
id: E9GJ31
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
type: ProteinReference
xref: uniprot P54313 424
organism: Rattus norvegicus

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
type: ProteinReference
xref: uniprot P54311 423
organism: Rattus norvegicus

uniprot A0A3Q1NGS8 316
type: UnificationXref
id: A0A3Q1NGS8
db: uniprot

Putative SNAP25 homologous protein SNAP30
type: ProteinReference
xref: uniprot Q9LMG8 228
organism: Arabidopsis thaliana

uniprot Q86YW0 123
type: UnificationXref
id: Q86YW0
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma
type: ProteinReference
xref: PTHR10336:SF173
xref: uniprot F1PS03 43
organism: Canis lupus familiaris

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
type: ProteinReference
xref: PTHR10336:SF106
xref: uniprot H9FVW1 73
organism: Macaca mulatta

G protein subunit beta 4
type: ProteinReference
xref: uniprot F7E427 368
organism: Ornithorhynchus anatinus

Vesicle-associated membrane protein 1
type: ProteinReference
xref: uniprot Q0V7N0 207
xref: PTHR45701:SF1
organism: Bos taurus

uniprot F7GU82 64
type: UnificationXref
id: F7GU82
db: uniprot

Protein kinase C
type: ProteinReference
xref: uniprot A0A2I3RQJ8 237
xref: PTHR24356:SF214
organism: Pan troglodytes

G protein subunit alpha 14
type: ProteinReference
xref: uniprot Q5EAP4 454
xref: PTHR10218:SF213
organism: Rattus norvegicus

uniprot O14775 396
type: UnificationXref
id: O14775
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
type: ProteinReference
xref: uniprot Q6PH57 471
organism: Danio rerio

uniprot F6XWE8 358
type: UnificationXref
id: F6XWE8
db: uniprot

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot A0A1D5Q3D7 8
xref: PTHR10336:SF31
organism: Macaca mulatta

uniprot O44419 186
type: UnificationXref
id: O44419
db: uniprot

uniprot Q7SBR2 120
type: UnificationXref
id: Q7SBR2
db: uniprot

Protein kinase C beta type
type: ProteinReference
xref: uniprot A8KBH6 243
xref: PTHR24356:SF158
organism: Xenopus tropicalis

uniprot F7GI54 379
type: UnificationXref
id: F7GI54
db: uniprot

G protein alpha q subunit
type: ProteinReference
xref: uniprot P23625 405
xref: PTHR10218:SF329
organism: Drosophila melanogaster

uniprot F1M324 36
type: UnificationXref
id: F1M324
db: uniprot

uniprot H9FVW1 73
type: UnificationXref
id: H9FVW1
db: uniprot

Dictyostelium purpureum
type: BioSource
xref: ncbitaxon 5786 342

uniprot G3V8K2 382
type: UnificationXref
id: G3V8K2
db: uniprot

uniprot Q8K2J0 126
type: UnificationXref
id: Q8K2J0
db: uniprot

uniprot Q15147 102
type: UnificationXref
id: Q15147
db: uniprot

GDP s11 sa9 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: GDP
stoichiometric coefficient: 1.0

uniprot Q90XF2 311
type: UnificationXref
id: Q90XF2
db: uniprot

PTHR19957:SF34
type: RelationshipXref
id: PTHR19957:SF34
db: PANTHER Family
relationship type: By Homology

uniprot P63218 441
type: UnificationXref
id: P63218
db: uniprot

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot Q9XWB7 144
organism: Caenorhabditis elegans

uniprot F6VPY1 355
type: UnificationXref
id: F6VPY1
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A1D5QIS2 155
xref: PTHR45701:SF7
organism: Macaca mulatta

uniprot F1R506 255
type: UnificationXref
id: F1R506
db: uniprot

uniprot Q99JE6 135
type: UnificationXref
id: Q99JE6
db: uniprot

uniprot P25455 90
type: UnificationXref
id: P25455
db: uniprot

GTP s1 sa1 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: GTP
stoichiometric coefficient: 1.0

uniprot E2R2S3 332
type: UnificationXref
id: E2R2S3
db: uniprot

uniprot Q04759 298
type: UnificationXref
id: Q04759
db: uniprot

uniprot Q944C1 133
type: UnificationXref
id: Q944C1
db: uniprot

PARTICIPANT STOICHIOMETRY re16 530
type: Stoichiometry
physical entity: Ca2+ channel
stoichiometric coefficient: 1.0

ncbitaxon 284812 94
type: UnificationXref
id: 284812
db: ncbitaxon

ncbitaxon 8364 58
type: UnificationXref
id: 8364
db: ncbitaxon

uniprot O00161 183
type: UnificationXref
id: O00161
db: uniprot

Protein kinase C
type: ProteinReference
xref: uniprot F7BYI4 261
xref: PTHR24356:SF158
organism: Macaca mulatta

Protein kinase C
type: ProteinReference
xref: uniprot Q7QCP8 307
xref: PTHR24356:SF240
organism: Anopheles gambiae

HETERODIMER_ASSOCIATION
type: RelationshipTypeVocabulary

ncbitaxon 3702 107
type: UnificationXref
id: 3702
db: ncbitaxon

Synaptosomal-associated protein
type: ProteinReference
xref: PTHR19305:SF4
xref: uniprot H2Q995 179
organism: Pan troglodytes

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
type: ProteinReference
xref: PTHR10336:SF106
xref: uniprot H2QJY5 69
organism: Pan troglodytes

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
type: ProteinReference
xref: PTHR10336:SF10
xref: uniprot E2RT75 35
organism: Canis lupus familiaris

MODULATION
type: Control
xref: MODULATION
controlled: STATE_TRANSITION_LEFT__Ca2_PLUS__channel-RIGHT__Ca2_PLUS__channel-_re16
controller: PKC

Oxytocin
type: SmallMolecule
feature: COMPLEX PARTICIPANT BINDING FEATURE s8 sa6 503
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Guanine nucleotide-binding protein (G protein), beta 5
type: ProteinReference
xref: uniprot F7EBE7 369
organism: Xenopus tropicalis

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
type: ProteinReference
xref: uniprot P59768 425
organism: Homo sapiens

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
type: ProteinReference
xref: uniprot P16520 400
organism: Homo sapiens

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F6V461 354
organism: Ornithorhynchus anatinus

Emericella nidulans
type: BioSource
xref: ncbitaxon 227321 215

PARTICIPANT STOICHIOMETRY re16 529
type: Stoichiometry
physical entity: Ca2+ channel
stoichiometric coefficient: 1.0

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q6PBR4 469
organism: Danio rerio

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
type: ProteinReference
xref: PTHR10336:SF12
xref: uniprot Q9NQ66 139
organism: Homo sapiens

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q6DGZ5 466
organism: Danio rerio

uniprot P20444 283
type: UnificationXref
id: P20444
db: uniprot

uniprot F6SSS3 351
type: UnificationXref
id: F6SSS3
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot J9P702 391
organism: Canis lupus familiaris

Isotocin receptor-like 2
type: ProteinReference
xref: uniprot E4W699 147
xref: PTHR24241:SF89
organism: Danio rerio

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma
type: ProteinReference
xref: PTHR10336:SF173
xref: uniprot A0A1D5R8E9 13
organism: Macaca mulatta

uniprot F1PLB3 42
type: UnificationXref
id: F1PLB3
db: uniprot

uniprot O09044 185
type: UnificationXref
id: O09044
db: uniprot

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot A8XRA5 29
xref: PTHR10336:SF6
organism: Caenorhabditis briggsae

uniprot A0A2I3TUD1 315
type: UnificationXref
id: A0A2I3TUD1
db: uniprot

STATE_TRANSITION_LEFT__PKC-RIGHT__PKC-_re8
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY re8 510
participant stoichiometry: PARTICIPANT STOICHIOMETRY re8 511
left: PKC
interaction type: STATE_TRANSITION
right: PKC

Vesicle associated membrane protein 8
type: ProteinReference
xref: PTHR45701:SF7
xref: uniprot A0A2I3SR99 157
organism: Pan troglodytes

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot E1BH60 32
organism: Bos taurus

Synaptosomal-associated protein
type: ProteinReference
xref: PTHR19305:SF4
xref: uniprot A0A1D5QYR9 156
organism: Macaca mulatta

uniprot Q3USB7 109
type: UnificationXref
id: Q3USB7
db: uniprot

uniprot P18489 190
type: UnificationXref
id: P18489
db: uniprot

uniprot F7EPG4 175
type: UnificationXref
id: F7EPG4
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma
type: ProteinReference
xref: uniprot F6TAH0 53
xref: PTHR10336:SF173
organism: Monodelphis domestica

uniprot F6W548 356
type: UnificationXref
id: F6W548
db: uniprot

uniprot F1MLS3 38
type: UnificationXref
id: F1MLS3
db: uniprot

uniprot P60877 195
type: UnificationXref
id: P60877
db: uniprot

Inactive phospholipase C-like protein 1
type: ProteinReference
xref: uniprot Q62688 113
organism: Rattus norvegicus

PARTICIPANT STOICHIOMETRY re24 521
type: Stoichiometry
physical entity: GDP
stoichiometric coefficient: 1.0

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot A0A2I3RVP2 17
xref: PTHR10336:SF29
organism: Pan troglodytes

uniprot Q9S7P9 230
type: UnificationXref
id: Q9S7P9
db: uniprot

PARTICIPANT STOICHIOMETRY re24 520
type: Stoichiometry
physical entity: Complex (GTP/G-Protein)
stoichiometric coefficient: 1.0

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
type: ProteinReference
xref: PTHR10336:SF106
xref: uniprot F6TQN3 54
organism: Monodelphis domestica

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma
type: ProteinReference
xref: PTHR10336:SF25
xref: uniprot A0A3Q1MMD9 21
organism: Bos taurus

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
type: ProteinReference
xref: uniprot F7FXA9 374
organism: Macaca mulatta

Guanine nucleotide-binding protein subunit beta-4
type: ProteinReference
xref: uniprot P29387 407
organism: Mus musculus

uniprot A0A1D5R985 236
type: UnificationXref
id: A0A1D5R985
db: uniprot

PARTICIPANT STOICHIOMETRY re24 518
type: Stoichiometry
physical entity: GTP
stoichiometric coefficient: 1.0

uniprot Q20636 446
type: UnificationXref
id: Q20636
db: uniprot

PARTICIPANT STOICHIOMETRY re24 519
type: Stoichiometry
physical entity: Complex (Oxytocin/Oxytocin Receptor)
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY re24 517
type: Stoichiometry
physical entity: Complex (Oxytocin/Oxytocin Receptor/ G-Protein/GDP)
stoichiometric coefficient: 1.0

Phosphoinositide phospholipase C (Fragment)
type: ProteinReference
xref: uniprot F1QLX2 45
xref: PTHR10336:SF173
organism: Danio rerio

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot H2QZN8 389
organism: Pan troglodytes

Synaptosomal-associated protein
type: ProteinReference
xref: uniprot F5HMS4 165
xref: PTHR19305:SF14
organism: Anopheles gambiae

Gnb2 protein
type: ProteinReference
xref: uniprot Q5BJ11 453
organism: Danio rerio

uniprot P62873 428
type: UnificationXref
id: P62873
db: uniprot

Saccharomyces cerevisiae
type: BioSource
xref: ncbitaxon 559292 92

uniprot F7A943 174
type: UnificationXref
id: F7A943
db: uniprot

uniprot F7E2P1 63
type: UnificationXref
id: F7E2P1
db: uniprot

Drosophila melanogaster
type: BioSource
xref: ncbitaxon 7227 86

uniprot K7BA21 76
type: UnificationXref
id: K7BA21
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
type: ProteinReference
xref: uniprot Q61011 461
organism: Mus musculus

Uncharacterized protein
type: ProteinReference
xref: PTHR19957:SF34
xref: uniprot H2Q3R5 178
organism: Pan troglodytes

Protein kinase C zeta type
type: ProteinReference
xref: uniprot Q02956 297
xref: PTHR24356:SF170
organism: Mus musculus

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma plc-3
type: ProteinReference
xref: uniprot Q22070 105
organism: Caenorhabditis elegans

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot F1P354 39
organism: Gallus gallus

uniprot H2RCB8 181
type: UnificationXref
id: H2RCB8
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
type: ProteinReference
xref: uniprot H9ZA60 74
xref: PTHR10336:SF10
organism: Macaca mulatta

Protein kinase C
type: ProteinReference
xref: uniprot F1R506 255
xref: PTHR24356:SF181
organism: Danio rerio

PTHR10218:SF213
type: RelationshipXref
id: PTHR10218:SF213
db: PANTHER Family
relationship type: By Homology

ncbitaxon 10090 26
type: UnificationXref
id: 10090
db: ncbitaxon

uniprot P63045 204
type: UnificationXref
id: P63045
db: uniprot

Protein kinase C eta type
type: ProteinReference
xref: uniprot Q64617 305
xref: PTHR24356:SF192
organism: Rattus norvegicus

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1
type: ProteinReference
xref: PTHR10336:SF29
xref: uniprot Q8K4D7 129
organism: Mus musculus

Protein kinase C gamma type
type: ProteinReference
xref: PTHR24356:SF162
xref: uniprot P63318 290
organism: Mus musculus

Protein kinase C gamma type
type: ProteinReference
xref: PTHR24356:SF162
xref: uniprot P63319 291
organism: Rattus norvegicus

AGAP001506-PA
type: ProteinReference
xref: uniprot Q7PXP3 473
organism: Anopheles gambiae

Guanine nucleotide-binding protein (G protein), alpha 14
type: ProteinReference
xref: uniprot Q66JF0 464
xref: PTHR10218:SF213
organism: Xenopus tropicalis

uniprot A0A1D5Q4D0 10
type: UnificationXref
id: A0A1D5Q4D0
db: uniprot

uniprot F7F580 373
type: UnificationXref
id: F7F580
db: uniprot

Protein kinase C-like 2
type: ProteinReference
xref: uniprot P90980 294
xref: PTHR24356:SF390
organism: Caenorhabditis elegans

uniprot P17343 401
type: UnificationXref
id: P17343
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma
type: ProteinReference
xref: uniprot E2RQM0 33
xref: PTHR10336:SF25
organism: Canis lupus familiaris

uniprot P29387 407
type: UnificationXref
id: P29387
db: uniprot

PKC
type: Protein
entity reference: PKC
feature: ACTIVE 146
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=PROTEIN

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
type: ProteinReference
xref: uniprot Q61016 462
organism: Mus musculus

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
type: ProteinReference
xref: uniprot Q61017 463
organism: Mus musculus

uniprot A0A2I3SHP7 18
type: UnificationXref
id: A0A2I3SHP7
db: uniprot

uniprot P10688 82
type: UnificationXref
id: P10688
db: uniprot

uniprot P63212 435
type: UnificationXref
id: P63212
db: uniprot

SNARE COMPLEX
type: ProteinReference
xref: P04532
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: SNARE COMPLEX Synonym: Synonym not specified Accession: P04532
comment: ENTITY_REFERENCE_ID_DESC=Oxytocin receptor mediated signaling pathway.PROTEIN.GENERIC.SNARE COMPLEX
member entity reference: Uncharacterized protein
member entity reference: Putative SNAP25 homologous protein SNAP30
member entity reference: SNAP25 homologous protein SNAP29
member entity reference: Synaptosomal-associated protein
member entity reference: Synaptosomal-associated protein 29
member entity reference: Synaptosomal-associated protein 25
member entity reference: Vesicle-associated membrane protein 2
member entity reference: Syntaxin 3A
member entity reference: Vesicle-associated membrane protein 1
member entity reference: Synaptobrevin
member entity reference: Vesicle-associated membrane protein 8
member entity reference: Synaptobrevin homolog 1
member entity reference: VAMP3 isoform 1
member entity reference: Vesicle associated membrane protein 8
member entity reference: Vesicle-associated membrane protein 3
member entity reference: VAMP2 isoform 3
member entity reference: Synaptosomal-associated protein 25-B
member entity reference: Putative synaptobrevin homologue SNC1/2 (Eurofung)
member entity reference: Synaptosomal-associated protein 23
member entity reference: Syntaxin-3
member entity reference: Neuronal synaptobrevin, isoform J
member entity reference: Synaptobrevin-1
member entity reference: Synaptobrevin homolog 2
member entity reference: Soluble NSF attachment protein 29
member entity reference: SNAP29 isoform 1
member entity reference: LD03592p
member entity reference: Syntaxin 3
member entity reference: Vesicle associated membrane protein 1
member entity reference: t-SNARE protein aex-4
member entity reference: Synaptosomal-associated protein 25-A
member entity reference: Vesicle-associated membrane protein 8 (Endobrevin)

TRIGGER
type: Control
xref: TRIGGER
controlled: muscle contraction
controller: Ca2+

uniprot A0A2I3SR99 157
type: UnificationXref
id: A0A2I3SR99
db: uniprot

uniprot F1QLX2 45
type: UnificationXref
id: F1QLX2
db: uniprot

STATE_TRANSITION_LEFT__Ca2_PLUS__channel-RIGHT__Ca2_PLUS__channel-_re16
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY re16 530
participant stoichiometry: PARTICIPANT STOICHIOMETRY re16 529
left: Ca2+ channel
interaction type: STATE_TRANSITION
right: Ca2+ channel

uniprot Q64617 305
type: UnificationXref
id: Q64617
db: uniprot

Synaptosomal-associated protein 29
type: ProteinReference
xref: uniprot Q9Z2P6 235
xref: PTHR19305:SF9
organism: Rattus norvegicus

Vesicle-associated membrane protein 8
type: ProteinReference
xref: PTHR45701:SF7
xref: uniprot Q9WUF4 234
organism: Rattus norvegicus

uniprot Q28FH0 448
type: UnificationXref
id: Q28FH0
db: uniprot

uniprot Q9Z1B3 145
type: UnificationXref
id: Q9Z1B3
db: uniprot

uniprot F6XMN6 258
type: UnificationXref
id: F6XMN6
db: uniprot

Synaptosomal-associated protein 25
type: ProteinReference
xref: uniprot Q5R1X1 216
xref: PTHR19305:SF5
organism: Pan troglodytes

uniprot F6TAH0 53
type: UnificationXref
id: F6TAH0
db: uniprot

uniprot P50148 417
type: UnificationXref
id: P50148
db: uniprot

uniprot P36975 194
type: UnificationXref
id: P36975
db: uniprot

Protein kinase C eta type
type: ProteinReference
xref: uniprot P23298 284
xref: PTHR24356:SF192
organism: Mus musculus

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot F1PL99 41
organism: Canis lupus familiaris

Xenopus tropicalis
type: BioSource
xref: ncbitaxon 8364 58

uniprot P05130 274
type: UnificationXref
id: P05130
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1
type: ProteinReference
xref: uniprot Q1RML2 103
xref: PTHR10336:SF29
organism: Bos taurus

TRIGGER
type: RelationshipTypeVocabulary

TRANSPORT_LEFT__Ca2_PLUS_-RIGHT__Ca2_PLUS_-_re17
type: TransportWithBiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: TRANSPORT
participant stoichiometry: PARTICIPANT STOICHIOMETRY re17 528
participant stoichiometry: PARTICIPANT STOICHIOMETRY re17 527
left: Ca2+
interaction type: TRANSPORT
right: Ca2+

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma
type: ProteinReference
xref: uniprot Q7QHE3 119
organism: Anopheles gambiae

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
type: ProteinReference
xref: PTHR10336:SF12
xref: uniprot F1PL90 40
organism: Canis lupus familiaris

PKC
type: Protein
entity reference: PKC
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=PROTEIN

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
type: ProteinReference
xref: uniprot O14610 395
organism: Homo sapiens

uniprot B7Q3T6 323
type: UnificationXref
id: B7Q3T6
db: uniprot

uniprot E2RT75 35
type: UnificationXref
id: E2RT75
db: uniprot

uniprot A8XTZ1 30
type: UnificationXref
id: A8XTZ1
db: uniprot

uniprot Q5ASG1 214
type: UnificationXref
id: Q5ASG1
db: uniprot

Oxytocin s8 sa6 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Oxytocin
stoichiometric coefficient: 1.0

Guanine nucleotide-binding protein subunit beta
type: ProteinReference
xref: uniprot P49177 416
organism: Arabidopsis thaliana

uniprot G5EBH0 65
type: UnificationXref
id: G5EBH0
db: uniprot

PARTICIPANT STOICHIOMETRY re6 512
type: Stoichiometry
physical entity: PIP2
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY re6 513
type: Stoichiometry
physical entity: IP3
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY re6 514
type: Stoichiometry
physical entity: DAG
stoichiometric coefficient: 1.0

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
type: ProteinReference
xref: uniprot P11017 399
organism: Bos taurus

Protein kinase C
type: ProteinReference
xref: uniprot E1BMG4 245
xref: PTHR24356:SF181
organism: Bos taurus

uniprot A8KBH6 243
type: UnificationXref
id: A8KBH6
db: uniprot

Protein kinase C eta type
type: ProteinReference
xref: uniprot P24723 285
xref: PTHR24356:SF192
organism: Homo sapiens

uniprot A8XRA5 29
type: UnificationXref
id: A8XRA5
db: uniprot

uniprot F1PS03 43
type: UnificationXref
id: F1PS03
db: uniprot

uniprot H2QJ75 68
type: UnificationXref
id: H2QJ75
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F7H6T7 380
organism: Macaca mulatta

uniprot P63026 201
type: UnificationXref
id: P63026
db: uniprot

uniprot P10894 83
type: UnificationXref
id: P10894
db: uniprot

endoplasmic reticulum
type: CellularLocationVocabulary
xref: GO GO:0005783 2

Vesicle associated membrane protein 8
type: ProteinReference
xref: PTHR45701:SF7
xref: uniprot E2QUL2 162
organism: Canis lupus familiaris

uniprot Q08BT6 301
type: UnificationXref
id: Q08BT6
db: uniprot

Guanine nucleotide-binding protein beta subunit
type: ProteinReference
xref: uniprot F5HH30 348
organism: Neurospora crassa

uniprot P43425 415
type: UnificationXref
id: P43425
db: uniprot

uniprot A4IGZ2 319
type: UnificationXref
id: A4IGZ2
db: uniprot

uniprot Q90Z40 479
type: UnificationXref
id: Q90Z40
db: uniprot

uniprot A0A1D5QXV8 12
type: UnificationXref
id: A0A1D5QXV8
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
type: ProteinReference
xref: uniprot P43425 415
organism: Rattus norvegicus

uniprot G5EEN8 177
type: UnificationXref
id: G5EEN8
db: uniprot

uniprot F7HC75 265
type: UnificationXref
id: F7HC75
db: uniprot

uniprot F1MKT3 37
type: UnificationXref
id: F1MKT3
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot A4IGZ2 319
organism: Xenopus tropicalis

uniprot Q28024 447
type: UnificationXref
id: Q28024
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
type: ProteinReference
xref: uniprot Q02158 99
organism: Dictyostelium discoideum

Protein kinase C epsilon type
type: ProteinReference
xref: uniprot Q02156 296
xref: PTHR24356:SF159
organism: Homo sapiens

uniprot A8WR64 244
type: UnificationXref
id: A8WR64
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
type: ProteinReference
xref: uniprot Q28024 447
organism: Bos taurus

ncbitaxon 665079 322
type: UnificationXref
id: 665079
db: ncbitaxon

uniprot P59768 425
type: UnificationXref
id: P59768
db: uniprot

PTHR24351:SF182
type: RelationshipXref
id: PTHR24351:SF182
db: PANTHER Family
relationship type: By Homology

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F6XWE8 358
organism: Monodelphis domestica

Synaptobrevin homolog 1
type: ProteinReference
xref: uniprot Q92356 225
organism: Schizosaccharomyces pombe

ncbitaxon 227321 215
type: UnificationXref
id: 227321
db: ncbitaxon

ncbitaxon 7668 187
type: UnificationXref
id: 7668
db: ncbitaxon

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__PLC_beta-RIGHT__PLC_beta-_re19
controller: Complex (GTP/G-Protein)

AGAP005911-PA
type: ProteinReference
xref: uniprot Q7Q6D4 476
organism: Anopheles gambiae

uniprot H9EU39 269
type: UnificationXref
id: H9EU39
db: uniprot

AGAP005913-PA
type: ProteinReference
xref: uniprot Q7Q6D2 474
organism: Anopheles gambiae

PTHR24356:SF240
type: RelationshipXref
id: PTHR24356:SF240
db: PANTHER Family
relationship type: By Homology

AGAP005912-PA
type: ProteinReference
xref: uniprot Q7Q6D3 475
organism: Anopheles gambiae

uniprot E1BQN6 246
type: UnificationXref
id: E1BQN6
db: uniprot

uniprot A0A1D5QLW6 11
type: UnificationXref
id: A0A1D5QLW6
db: uniprot

uniprot Q5ZJ03 460
type: UnificationXref
id: Q5ZJ03
db: uniprot

Bos taurus
type: BioSource
xref: ncbitaxon 9913 22

uniprot Q7QHE3 119
type: UnificationXref
id: Q7QHE3
db: uniprot

uniprot Q8K3R3 128
type: UnificationXref
id: Q8K3R3
db: uniprot

Ornithorhynchus anatinus
type: BioSource
xref: ncbitaxon 9258 56

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot H2Q3W7 386
organism: Pan troglodytes

uniprot E2RQM0 33
type: UnificationXref
id: E2RQM0
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
type: ProteinReference
xref: uniprot P10895 84
xref: PTHR10336:SF80
organism: Bos taurus

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
type: ProteinReference
xref: uniprot P10894 83
xref: PTHR10336:SF12
organism: Bos taurus

uniprot Q9UK08 485
type: UnificationXref
id: Q9UK08
db: uniprot

Oxytocin Receptor s9 sa7 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Oxytocin Receptor
stoichiometric coefficient: 1.0

G Protein s4 sa4 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: G-Protein
stoichiometric coefficient: 1.0

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
type: ProteinReference
xref: uniprot O89040 78
xref: PTHR10336:SF10
organism: Rattus norvegicus

ncbitaxon 6669 339
type: UnificationXref
id: 6669
db: ncbitaxon

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma
type: ProteinReference
xref: uniprot F7BVQ1 61
xref: PTHR10336:SF25
organism: Monodelphis domestica

uniprot F7G1U7 376
type: UnificationXref
id: F7G1U7
db: uniprot

uniprot H2R3A6 390
type: UnificationXref
id: H2R3A6
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q28H40 449
organism: Xenopus tropicalis

uniprot P63025 200
type: UnificationXref
id: P63025
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
type: ProteinReference
xref: uniprot P30671 410
organism: Bos taurus

G Protein s10 sa8 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: G-Protein
stoichiometric coefficient: 1.0

GTP
type: SmallMolecule
feature: COMPLEX PARTICIPANT BINDING FEATURE s1 sa1 489
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Ixodes scapularis
type: BioSource
xref: ncbitaxon 6945 324

uniprot J9JHK9 75
type: UnificationXref
id: J9JHK9
db: uniprot

uniprot P63215 438
type: UnificationXref
id: P63215
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
type: ProteinReference
xref: PTHR10336:SF173
xref: uniprot P08487 79
organism: Bos taurus

uniprot E1C795 331
type: UnificationXref
id: E1C795
db: uniprot

PTHR24356:SF214
type: RelationshipXref
id: PTHR24356:SF214
db: PANTHER Family
relationship type: By Homology

Protein kinase C
type: ProteinReference
xref: uniprot A0A2I3SR38 238
xref: PTHR24356:SF181
organism: Pan troglodytes

Guanine nucleotide-binding protein subunit beta
type: ProteinReference
xref: uniprot F1A421 341
organism: Dictyostelium purpureum

uniprot H2RB55 71
type: UnificationXref
id: H2RB55
db: uniprot

uniprot F1NLV4 344
type: UnificationXref
id: F1NLV4
db: uniprot

Canis lupus familiaris
type: BioSource
xref: ncbitaxon 9615 34

uniprot Q7Q6D4 476
type: UnificationXref
id: Q7Q6D4
db: uniprot

Protein kinase C epsilon type
type: ProteinReference
xref: PTHR24356:SF159
xref: uniprot Q08BT6 301
organism: Xenopus tropicalis

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A3Q1NGS8 316
organism: Bos taurus

G protein subunit beta 4
type: ProteinReference
xref: uniprot H2QNS5 388
organism: Pan troglodytes

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F7G7I9 378
organism: Ornithorhynchus anatinus

uniprot H2QJY5 69
type: UnificationXref
id: H2QJY5
db: uniprot

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot Q7SE08 122
organism: Neurospora crassa

uniprot P23298 284
type: UnificationXref
id: P23298
db: uniprot

uniprot Q9BV40 226
type: UnificationXref
id: Q9BV40
db: uniprot

VAMP3 isoform 1
type: ProteinReference
xref: PTHR45701:SF6
xref: uniprot G2HIJ9 176
organism: Pan troglodytes

PTHR45701:SF10
type: RelationshipXref
id: PTHR45701:SF10
db: PANTHER Family
relationship type: By Homology

Synaptosomal-associated protein
type: ProteinReference
xref: PTHR19305:SF5
xref: uniprot E2R907 163
organism: Canis lupus familiaris

uniprot Q02111 295
type: UnificationXref
id: Q02111
db: uniprot

Ca2+
type: SmallMolecule
comment: SPECIES_TYPE=ION

Guanine nucleotide-binding protein subunit alpha-14
type: ProteinReference
xref: uniprot P30677 411
xref: PTHR10218:SF213
organism: Mus musculus

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F7CFG8 365
organism: Monodelphis domestica

Gallus gallus
type: BioSource
xref: ncbitaxon 9031 24

uniprot A4IFL6 318
type: UnificationXref
id: A4IFL6
db: uniprot

uniprot Q61017 463
type: UnificationXref
id: Q61017
db: uniprot

Protein kinase C theta type
type: ProteinReference
xref: uniprot Q02111 295
xref: PTHR24356:SF181
organism: Mus musculus

uniprot E2QUL2 162
type: UnificationXref
id: E2QUL2
db: uniprot

Oxytocin
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Protein kinase C delta type
type: ProteinReference
xref: PTHR24356:SF365
xref: uniprot Q5PU49 303
organism: Canis lupus familiaris

Guanine nucleotide-binding protein subunit alpha-11
type: ProteinReference
xref: uniprot P21278 403
xref: PTHR10218:SF328
organism: Mus musculus

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F7GI54 379
organism: Monodelphis domestica

Uncharacterized protein
type: ProteinReference
xref: PTHR10218:SF328
xref: uniprot F7ECA6 370
organism: Monodelphis domestica

Guanine nucleotide-binding protein G(q) subunit alpha
type: ProteinReference
xref: PTHR10218:SF316
xref: uniprot P21279 404
organism: Mus musculus

uniprot Q10282 444
type: UnificationXref
id: Q10282
db: uniprot

uniprot F5HMS4 165
type: UnificationXref
id: F5HMS4
db: uniprot

SNAP25 homologous protein SNAP33
type: ProteinReference
xref: uniprot Q9S7P9 230
organism: Arabidopsis thaliana

ncbitaxon 6239 66
type: UnificationXref
id: 6239
db: ncbitaxon

uniprot F7CFG8 365
type: UnificationXref
id: F7CFG8
db: uniprot

Synaptosomal-associated protein
type: ProteinReference
xref: uniprot Q9VH76 232
xref: PTHR19305:SF14
organism: Drosophila melanogaster

uniprot P63216 439
type: UnificationXref
id: P63216
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
type: ProteinReference
xref: PTHR10336:SF106
xref: uniprot F1PLB3 42
organism: Canis lupus familiaris

Phosphoinositide phospholipase C 8
type: ProteinReference
xref: uniprot Q9STZ3 142
organism: Arabidopsis thaliana

Gnb3 protein
type: ProteinReference
xref: uniprot Q6P025 468
organism: Danio rerio

uniprot H2QM02 148
type: UnificationXref
id: H2QM02
db: uniprot

Protein kinase C beta type
type: ProteinReference
xref: uniprot P68404 292
xref: PTHR24356:SF158
organism: Mus musculus

Uncharacterized protein
type: ProteinReference
xref: uniprot Q5KI86 456
organism: Cryptococcus neoformans

uniprot F7EBE7 369
type: UnificationXref
id: F7EBE7
db: uniprot

Guanine nucleotide binding protein, beta subunit
type: ProteinReference
xref: uniprot E9FUX0 338
organism: Daphnia pulex

uniprot O60262 397
type: UnificationXref
id: O60262
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
type: ProteinReference
xref: uniprot P51178 95
xref: PTHR10336:SF80
organism: Homo sapiens

uniprot F7D5G3 62
type: UnificationXref
id: F7D5G3
db: uniprot

uniprot Q7PW25 118
type: UnificationXref
id: Q7PW25
db: uniprot

eco ECO:0000305 160
type: UnificationXref
id: ECO:0000305
db: eco

Guanine nucleotide-binding protein (G protein), q polypeptide
type: ProteinReference
xref: PTHR10218:SF316
xref: uniprot Q28FH0 448
organism: Xenopus tropicalis

uniprot Q8IA75 125
type: UnificationXref
id: Q8IA75
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
type: ProteinReference
xref: PTHR10336:SF12
xref: uniprot F6VVA6 55
organism: Ornithorhynchus anatinus

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
type: ProteinReference
xref: uniprot Q9UBI6 484
organism: Homo sapiens

uniprot H2PZA6 384
type: UnificationXref
id: H2PZA6
db: uniprot

Protein kinase C
type: ProteinReference
xref: uniprot F7DVL1 262
xref: PTHR24356:SF214
organism: Xenopus tropicalis

Protein kinase C
type: ProteinReference
xref: uniprot H2QAS6 267
xref: PTHR24356:SF158
organism: Pan troglodytes

uniprot Q9WUF4 234
type: UnificationXref
id: Q9WUF4
db: uniprot

uniprot Q6PBY0 470
type: UnificationXref
id: Q6PBY0
db: uniprot

Oxytocin
type: SmallMolecule
cellular location: vesicle
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Uncharacterized protein
type: ProteinReference
xref: uniprot F6PVT7 350
organism: Monodelphis domestica

uniprot Q99P84 136
type: UnificationXref
id: Q99P84
db: uniprot

Protein kinase C
type: ProteinReference
xref: uniprot E1BQN6 246
xref: PTHR24356:SF170
organism: Gallus gallus

Guanine nucleotide-binding protein subunit alpha-14
type: ProteinReference
xref: uniprot F7AQR3 362
xref: PTHR10218:SF213
organism: Macaca mulatta

uniprot E1BA29 329
type: UnificationXref
id: E1BA29
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F6Y3N2 359
organism: Monodelphis domestica

THO complex subunit, putative
type: ProteinReference
xref: uniprot B7Q3T6 323
organism: Ixodes scapularis

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F6XHP0 357
organism: Macaca mulatta

uniprot H2QNS5 388
type: UnificationXref
id: H2QNS5
db: uniprot

uniprot Q1RML2 103
type: UnificationXref
id: Q1RML2
db: uniprot

Phosphoinositide phospholipase C
type: ProteinReference
xref: PTHR10336:SF6
xref: uniprot H2RB55 71
organism: Pan troglodytes

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
type: ProteinReference
xref: uniprot Q9DAS9 481
organism: Mus musculus

uniprot F7BIC2 260
type: UnificationXref
id: F7BIC2
db: uniprot

Protein kinase C eta type
type: ProteinReference
xref: uniprot H2Q8F2 266
xref: PTHR24356:SF192
organism: Pan troglodytes

uniprot F1NU41 345
type: UnificationXref
id: F1NU41
db: uniprot

uniprot Q6DH55 467
type: UnificationXref
id: Q6DH55
db: uniprot

Guanine nucleotide-binding protein subunit alpha-14
type: ProteinReference
xref: uniprot O95837 398
xref: PTHR10218:SF213
organism: Homo sapiens

uniprot O70404 188
type: UnificationXref
id: O70404
db: uniprot

uniprot Q7SZZ5 223
type: UnificationXref
id: Q7SZZ5
db: uniprot

uniprot F1MYW8 343
type: UnificationXref
id: F1MYW8
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F7ASR8 363
organism: Macaca mulatta

Protein kinase C beta type
type: ProteinReference
xref: PTHR24356:SF158
xref: uniprot P05771 275
organism: Homo sapiens

Guanine nucleotide-binding protein subunit beta-1
type: ProteinReference
xref: uniprot P26308 406
organism: Drosophila melanogaster

Oryza sativa
type: BioSource
xref: ncbitaxon 39947 117

uniprot Q9WTQ0 312
type: UnificationXref
id: Q9WTQ0
db: uniprot

uniprot E2RGU7 248
type: UnificationXref
id: E2RGU7
db: uniprot

Oxytocin receptor
type: ProteinReference
xref: PTHR24241:SF89
xref: uniprot H2QM02 148
organism: Pan troglodytes

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot Q7SBR2 120
organism: Neurospora crassa

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot F1R8S3 47
xref: PTHR10336:SF80
organism: Danio rerio

uniprot O02495 184
type: UnificationXref
id: O02495
db: uniprot

Protein kinase C
type: ProteinReference
xref: uniprot A0A1D5R985 236
xref: PTHR24356:SF193
organism: Macaca mulatta

Uncharacterized protein
type: ProteinReference
xref: uniprot F7CXD0 367
organism: Monodelphis domestica

G-protein beta subunit
type: ProteinReference
xref: uniprot Q5BH99 452
organism: Emericella nidulans

GO GO:0031982 3
type: UnificationXref
id: GO:0031982
db: GO

uniprot P18851 402
type: UnificationXref
id: P18851
db: uniprot

Synaptosomal-associated protein
type: ProteinReference
xref: PTHR19305:SF5
xref: uniprot F6VM87 169
organism: Monodelphis domestica

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
type: ProteinReference
xref: uniprot Q99P84 136
xref: PTHR10336:SF6
organism: Rattus norvegicus

Protein kinase C delta type
type: ProteinReference
xref: PTHR24356:SF365
xref: uniprot P28867 286
organism: Mus musculus

Protein kinase C
type: ProteinReference
xref: uniprot E2RNP2 249
xref: PTHR24356:SF181
organism: Canis lupus familiaris

uniprot Q5RKP9 458
type: UnificationXref
id: Q5RKP9
db: uniprot

uniprot Q9UBI6 484
type: UnificationXref
id: Q9UBI6
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR10218:SF316
xref: uniprot Q5F3B5 455
organism: Gallus gallus

ncbitaxon 13616 51
type: UnificationXref
id: 13616
db: ncbitaxon

uniprot Q39033 108
type: UnificationXref
id: Q39033
db: uniprot

Anopheles gambiae
type: BioSource
xref: ncbitaxon 7165 49

uniprot P19174 89
type: UnificationXref
id: P19174
db: uniprot

uniprot E1BWA3 247
type: UnificationXref
id: E1BWA3
db: uniprot

Protein kinase C
type: ProteinReference
xref: uniprot F7A632 259
xref: PTHR24356:SF158
organism: Monodelphis domestica

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F1MYW8 343
organism: Bos taurus

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
type: ProteinReference
xref: uniprot Q9P212 140
xref: PTHR10336:SF6
organism: Homo sapiens

uniprot H2Q3R5 178
type: UnificationXref
id: H2Q3R5
db: uniprot

uniprot Q5R1X1 216
type: UnificationXref
id: Q5R1X1
db: uniprot

TRANSPORT_LEFT__Oxytocin-RIGHT__Oxytocin-_re12
type: TransportWithBiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: TRANSPORT
participant stoichiometry: PARTICIPANT STOICHIOMETRY re12 532
participant stoichiometry: PARTICIPANT STOICHIOMETRY re12 531
left: Oxytocin
interaction type: TRANSPORT
right: Oxytocin

uniprot Q5KI86 456
type: UnificationXref
id: Q5KI86
db: uniprot

uniprot F1PJE5 346
type: UnificationXref
id: F1PJE5
db: uniprot

uniprot P30559 149
type: UnificationXref
id: P30559
db: uniprot

Synaptosomal-associated protein 23
type: ProteinReference
xref: PTHR19305:SF4
xref: uniprot O09044 185
organism: Mus musculus

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F7BB02 364
organism: Macaca mulatta

uniprot K6ZCJ5 392
type: UnificationXref
id: K6ZCJ5
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__PKC-RIGHT__PKC-_re8
controller: DAG

Gnb1l protein
type: ProteinReference
xref: uniprot Q803H5 477
organism: Danio rerio

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot K7C8Z4 77
xref: PTHR10336:SF80
organism: Pan troglodytes

Oxytocin Receptor
type: Protein
entity reference: Oxytocin Receptor
feature: COMPLEX PARTICIPANT BINDING FEATURE s13 sa11 501
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=PROTEIN

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot F6SRP9 52
xref: PTHR10336:SF80
organism: Macaca mulatta

uniprot F7ERP8 371
type: UnificationXref
id: F7ERP8
db: uniprot

DISSOCIATION_LEFT__PIP2-RIGHT__IP3-_DAG-_re6
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: DISSOCIATION
participant stoichiometry: PARTICIPANT STOICHIOMETRY re6 513
participant stoichiometry: PARTICIPANT STOICHIOMETRY re6 512
participant stoichiometry: PARTICIPANT STOICHIOMETRY re6 514
left: PIP2
interaction type: DISSOCIATION
right: IP3
right: DAG

Synaptosomal-associated protein
type: ProteinReference
xref: uniprot A8X8S6 161
xref: PTHR19305:SF14
organism: Caenorhabditis briggsae

Oxytocin
type: SmallMolecule
feature: COMPLEX PARTICIPANT BINDING FEATURE s12 sa10 499
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot O14610 395
type: UnificationXref
id: O14610
db: uniprot

uniprot Q19266 302
type: UnificationXref
id: Q19266
db: uniprot

uniprot Q5TZ66 217
type: UnificationXref
id: Q5TZ66
db: uniprot

uniprot P62874 429
type: UnificationXref
id: P62874
db: uniprot

Vesicle-associated membrane protein 1
type: ProteinReference
xref: PTHR45701:SF1
xref: uniprot Q63666 219
organism: Rattus norvegicus

G-Protein
type: Protein
entity reference: G-Protein
feature: COMPLEX PARTICIPANT BINDING FEATURE s2 sa2 491
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=PROTEIN

uniprot P32383 91
type: UnificationXref
id: P32383
db: uniprot

Vesicle-associated membrane protein 2
type: ProteinReference
xref: uniprot Q7SZZ5 223
organism: Danio rerio

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q3KRE3 450
organism: Rattus norvegicus

By Homology
type: RelationshipTypeVocabulary

Protein kinase C epsilon type
type: ProteinReference
xref: PTHR24356:SF159
xref: uniprot P16054 281
organism: Mus musculus

vesicle
type: CellularLocationVocabulary
xref: GO GO:0031982 3

uniprot F7H3B3 264
type: UnificationXref
id: F7H3B3
db: uniprot

uniprot A0A3Q1MRR6 240
type: UnificationXref
id: A0A3Q1MRR6
db: uniprot

Protein kinase C delta type
type: ProteinReference
xref: PTHR24356:SF365
xref: uniprot F7EG64 263
organism: Xenopus tropicalis

G protein subunit beta 5
type: ProteinReference
xref: uniprot E2RHY4 336
organism: Canis lupus familiaris

uniprot P16885 87
type: UnificationXref
id: P16885
db: uniprot

uniprot Q3T0Y8 213
type: UnificationXref
id: Q3T0Y8
db: uniprot

Protein kinase C delta type
type: ProteinReference
xref: PTHR24356:SF365
xref: uniprot F1P3G1 254
organism: Gallus gallus

PARTICIPANT STOICHIOMETRY re8 511
type: Stoichiometry
physical entity: PKC
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY re8 510
type: Stoichiometry
physical entity: PKC
stoichiometric coefficient: 1.0

uniprot H2QAS6 267
type: UnificationXref
id: H2QAS6
db: uniprot

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
type: ProteinReference
xref: uniprot O60262 397
organism: Homo sapiens

Phosphoinositide phospholipase C
type: ProteinReference
xref: PTHR10336:SF33
xref: uniprot D4A978 31
organism: Rattus norvegicus

ncbitaxon 7739 327
type: UnificationXref
id: 7739
db: ncbitaxon

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4
type: ProteinReference
xref: PTHR10336:SF31
xref: uniprot Q8K3R3 128
organism: Mus musculus

uniprot A0A2I3RVP2 17
type: UnificationXref
id: A0A2I3RVP2
db: uniprot

uniprot P08487 79
type: UnificationXref
id: P08487
db: uniprot

uniprot P38408 413
type: UnificationXref
id: P38408
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot D3ZLD6 328
organism: Rattus norvegicus

uniprot Q5F3B5 455
type: UnificationXref
id: Q5F3B5
db: uniprot

uniprot F6SD46 50
type: UnificationXref
id: F6SD46
db: uniprot

uniprot P60878 196
type: UnificationXref
id: P60878
db: uniprot

TRANSPORT_LEFT__Oxytocin-RIGHT__Oxytocin-_re25
type: TransportWithBiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: TRANSPORT
participant stoichiometry: PARTICIPANT STOICHIOMETRY re25 516
participant stoichiometry: PARTICIPANT STOICHIOMETRY re25 515
left: Oxytocin
interaction type: TRANSPORT
right: Oxytocin

uniprot G5EFI8 67
type: UnificationXref
id: G5EFI8
db: uniprot

uniprot P09216 277
type: UnificationXref
id: P09216
db: uniprot

PTHR19305:SF5
type: RelationshipXref
id: PTHR19305:SF5
db: PANTHER Family
relationship type: By Homology

uniprot P31109 192
type: UnificationXref
id: P31109
db: uniprot

Schizosaccharomyces pombe
type: BioSource
xref: ncbitaxon 284812 94

uniprot P49177 416
type: UnificationXref
id: P49177
db: uniprot

uniprot G3V6P8 381
type: UnificationXref
id: G3V6P8
db: uniprot

PTHR19305:SF9
type: RelationshipXref
id: PTHR19305:SF9
db: PANTHER Family
relationship type: By Homology

uniprot P60880 198
type: UnificationXref
id: P60880
db: uniprot

uniprot F6Z5I2 173
type: UnificationXref
id: F6Z5I2
db: uniprot

PLC beta
type: ProteinReference
xref: P04530
standard name: Phospholipase C beta
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: PLC beta Synonym: Synonym not specified Accession: P04530
comment: ENTITY_REFERENCE_ID_DESC=Oxytocin receptor mediated signaling pathway.PROTEIN.GENERIC.PLC beta
member entity reference: Inactive phospholipase C-like protein 1
member entity reference: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma plc-3
member entity reference: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
member entity reference: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
member entity reference: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma
member entity reference: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
member entity reference: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
member entity reference: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
member entity reference: Phosphoinositide phospholipase C
member entity reference: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
member entity reference: Inactive phospholipase C-like protein 2
member entity reference: Uncharacterized protein
member entity reference: Phosphoinositide phospholipase C 5
member entity reference: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1
member entity reference: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
member entity reference: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
member entity reference: Phosphoinositide phospholipase C (Fragment)
member entity reference: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1
member entity reference: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4
member entity reference: Phosphoinositide phospholipase C 4
member entity reference: Phosphoinositide phospholipase C 7
member entity reference: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II
member entity reference: Phosphoinositide phospholipase C 1
member entity reference: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4
member entity reference: Phosphoinositide phospholipase C 2

PTHR19305:SF4
type: RelationshipXref
id: PTHR19305:SF4
db: PANTHER Family
relationship type: By Homology

uniprot F1R8S3 47
type: UnificationXref
id: F1R8S3
db: uniprot

DISSOCIATION
type: InteractionVocabulary

uniprot Q6Z3Y9 116
type: UnificationXref
id: Q6Z3Y9
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q0VFC4 443
organism: Xenopus tropicalis

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q6TH03 472
organism: Danio rerio

ncbitaxon 44689 100
type: UnificationXref
id: 44689
db: ncbitaxon

Oxytocin Receptor
type: Protein
entity reference: Oxytocin Receptor
feature: COMPLEX PARTICIPANT BINDING FEATURE s3 sa3 493
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=PROTEIN

Guanine nucleotide-binding protein subunit beta-2
type: ProteinReference
xref: uniprot Q20636 446
organism: Caenorhabditis elegans

uniprot P13217 85
type: UnificationXref
id: P13217
db: uniprot

GNB4 protein
type: ProteinReference
xref: uniprot A5PKD6 320
organism: Bos taurus

uniprot Q7T2C5 309
type: UnificationXref
id: Q7T2C5
db: uniprot

uniprot Q9STZ3 142
type: UnificationXref
id: Q9STZ3
db: uniprot

GDP
type: SmallMolecule
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Homo sapiens
type: BioSource
xref: ncbitaxon 9606 88

Oxytocin Receptor s3 sa3 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Oxytocin Receptor
stoichiometric coefficient: 1.0

uniprot Q944C2 134
type: UnificationXref
id: Q944C2
db: uniprot

Supraoptic nucleus also Amygdala and uterus c6
type: CellularLocationVocabulary
comment: Supraoptic nucleus (also Amygdala and uterus)

uniprot Q6PHV0 222
type: UnificationXref
id: Q6PHV0
db: uniprot

uniprot K7CBH8 270
type: UnificationXref
id: K7CBH8
db: uniprot

uniprot P50151 419
type: UnificationXref
id: P50151
db: uniprot

uniprot P26308 406
type: UnificationXref
id: P26308
db: uniprot

Synaptosomal-associated protein
type: ProteinReference
xref: uniprot Q28HP6 211
xref: PTHR19305:SF5
organism: Xenopus tropicalis

ncbitaxon 7955 46
type: UnificationXref
id: 7955
db: ncbitaxon

uniprot F6TFY2 352
type: UnificationXref
id: F6TFY2
db: uniprot

uniprot Q9HAV0 482
type: UnificationXref
id: Q9HAV0
db: uniprot

uniprot Q6P025 468
type: UnificationXref
id: Q6P025
db: uniprot

uniprot Q7Q6D2 474
type: UnificationXref
id: Q7Q6D2
db: uniprot

uniprot E2R9G5 334
type: UnificationXref
id: E2R9G5
db: uniprot

Strongylocentrotus purpuratus
type: BioSource
xref: ncbitaxon 7668 187

uniprot F7CXD0 367
type: UnificationXref
id: F7CXD0
db: uniprot

uniprot Q6TH03 472
type: UnificationXref
id: Q6TH03
db: uniprot

uniprot F1P354 39
type: UnificationXref
id: F1P354
db: uniprot

uniprot Q21754 104
type: UnificationXref
id: Q21754
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot E1C795 331
organism: Gallus gallus

uniprot P10686 80
type: UnificationXref
id: P10686
db: uniprot

uniprot Q9JID2 483
type: UnificationXref
id: Q9JID2
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1
type: ProteinReference
xref: uniprot P32383 91
organism: Saccharomyces cerevisiae

PTHR10336:SF173
type: RelationshipXref
id: PTHR10336:SF173
db: PANTHER Family
relationship type: By Homology

uniprot P63319 291
type: UnificationXref
id: P63319
db: uniprot

uniprot Q15836 209
type: UnificationXref
id: Q15836
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot R4GKD1 487
organism: Gallus gallus

Oxytocin
type: SmallMolecule
cellular location: endoplasmic reticulum
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Atypical protein kinase C
type: ProteinReference
xref: PTHR24356:SF303
xref: uniprot A1Z9X0 242
organism: Drosophila melanogaster

uniprot Q9DAS9 481
type: UnificationXref
id: Q9DAS9
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F7ES96 372
organism: Macaca mulatta

uniprot F1P3G1 254
type: UnificationXref
id: F1P3G1
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F1NLV4 344
organism: Gallus gallus

uniprot P16054 281
type: UnificationXref
id: P16054
db: uniprot

uniprot Q64704 220
type: UnificationXref
id: Q64704
db: uniprot

Guanine nucleotide-binding protein (G protein), q polypeptide
type: ProteinReference
xref: uniprot B8JLJ7 325
xref: PTHR10218:SF316
organism: Danio rerio

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot G3V8K2 382
organism: Rattus norvegicus

Synaptobrevin homolog 1
type: ProteinReference
xref: uniprot P31109 192
organism: Saccharomyces cerevisiae

uniprot P16520 400
type: UnificationXref
id: P16520
db: uniprot

uniprot A1Z9X0 242
type: UnificationXref
id: A1Z9X0
db: uniprot

uniprot P50150 418
type: UnificationXref
id: P50150
db: uniprot

uniprot F7ECA6 370
type: UnificationXref
id: F7ECA6
db: uniprot

uniprot D4A978 31
type: UnificationXref
id: D4A978
db: uniprot

Phosphoinositide phospholipase C
type: ProteinReference
xref: PTHR10336:SF31
xref: uniprot F1MKT3 37
organism: Bos taurus

Protein kinase C
type: ProteinReference
xref: PTHR24356:SF158
xref: uniprot Q7T2C5 309
organism: Danio rerio

uniprot A0A1D5QYR9 156
type: UnificationXref
id: A0A1D5QYR9
db: uniprot

Guanine nucleotide-binding protein beta subunit
type: ProteinReference
xref: uniprot A7EDU2 321
organism: Sclerotinia sclerotiorum

uniprot Q7SE08 122
type: UnificationXref
id: Q7SE08
db: uniprot

Complex (Oxytocin Receptor/G-Protein/ GDP)
type: Complex
component stoichiometry: G Protein s4 sa4 STOICHIOMETRY ID COMPLEX
component stoichiometry: GDP s6 sa5 STOICHIOMETRY ID COMPLEX
component stoichiometry: Oxytocin Receptor s3 sa3 STOICHIOMETRY ID COMPLEX
component: Oxytocin Receptor
component: GDP
component: G-Protein
feature: COMPLEX BINDING FEATURE s60 a82 492
feature: COMPLEX BINDING FEATURE s60 a82 494
feature: COMPLEX BINDING FEATURE s60 a82 496
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8

SNAP29 isoform 1
type: ProteinReference
xref: PTHR19305:SF9
xref: uniprot H2QLA1 180
organism: Pan troglodytes

uniprot P30671 410
type: UnificationXref
id: P30671
db: uniprot

uniprot Q6PBR4 469
type: UnificationXref
id: Q6PBR4
db: uniprot

ACTIVE 146
type: EntityFeature
comment: Active state

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
type: ProteinReference
xref: uniprot A0A2J8QDF6 20
xref: PTHR10336:SF10
organism: Pan troglodytes

uniprot F6THW2 353
type: UnificationXref
id: F6THW2
db: uniprot

Inactive phospholipase C-like protein 1
type: ProteinReference
xref: uniprot Q3USB7 109
organism: Mus musculus

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
type: ProteinReference
xref: PTHR10336:SF25
xref: uniprot P16885 87
organism: Homo sapiens

Protein kinase C theta type
type: ProteinReference
xref: uniprot Q9WTQ0 312
xref: PTHR24356:SF181
organism: Rattus norvegicus

Dictyostelium discoideum
type: BioSource
xref: ncbitaxon 44689 100

uniprot Q5XGD8 459
type: UnificationXref
id: Q5XGD8
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma
type: ProteinReference
xref: PTHR10336:SF173
xref: uniprot F6Z8A1 57
organism: Xenopus tropicalis

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F2Z3T8 347
organism: Rattus norvegicus

HETERODIMER_ASSOCIATION
type: InteractionVocabulary

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
type: ProteinReference
xref: uniprot P10688 82
xref: PTHR10336:SF80
organism: Rattus norvegicus

uniprot E1BMG4 245
type: UnificationXref
id: E1BMG4
db: uniprot

uniprot H2Q8F2 266
type: UnificationXref
id: H2Q8F2
db: uniprot

IC
type: EvidenceCodeVocabulary
xref: eco ECO:0000305 160

PKC
type: ProteinReference
xref: P04533
standard name: Protein kinase C
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: PKC Synonym: Protein Kinase C Accession: P04533
comment: ENTITY_REFERENCE_ID_DESC=Oxytocin receptor mediated signaling pathway.PROTEIN.GENERIC.PKC
member entity reference: Protein kinase C iota type
member entity reference: Protein kinase C gamma type (Fragment)
member entity reference: Protein kinase C epsilon type
member entity reference: Protein kinase C beta type
member entity reference: Protein kinase C
member entity reference: Protein kinase C delta type
member entity reference: Protein kinase C-like 3
member entity reference: Protein kinase C theta type
member entity reference: Protein kinase C, eye isozyme
member entity reference: Protein kinase C-like 1B
member entity reference: Protein kinase C-like 1
member entity reference: Protein kinase C zeta type
member entity reference: Protein kinase C eta type
member entity reference: Protein kinase C gamma type
member entity reference: AGAP012252-PA (Fragment)
member entity reference: Atypical protein kinase C
member entity reference: Protein kinase C alpha type
member entity reference: Putative protein kinase C delta type homolog
member entity reference: Protein kinase C-like 2
member entity reference: Protein kinase C, brain isozyme

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot K7E376 394
organism: Monodelphis domestica

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
type: ProteinReference
xref: PTHR10336:SF11
xref: uniprot J9JHK9 75
organism: Canis lupus familiaris

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
type: ProteinReference
xref: uniprot Q80SZ7 478
organism: Mus musculus

Protein kinase C zeta type
type: ProteinReference
xref: uniprot P09217 278
xref: PTHR24356:SF170
organism: Rattus norvegicus

Protein kinase C epsilon type
type: ProteinReference
xref: uniprot P09216 277
xref: PTHR24356:SF159
organism: Rattus norvegicus

uniprot F6UFJ7 168
type: UnificationXref
id: F6UFJ7
db: uniprot

Protein kinase C delta type
type: ProteinReference
xref: PTHR24356:SF365
xref: uniprot P09215 276
organism: Rattus norvegicus

DISSOCIATION_LEFT__Complex__Oxytocin_Oxytocin_Receptor__G_Protein_GDP_-_GTP-RIGHT__Complex__Oxytocin_Oxytocin_Receptor_-_Complex__GTP_G_Protein_-_GDP-_re24
type: ComplexAssembly
spontaneous: false
conversion direction: LEFT_TO_RIGHT
xref: DISSOCIATION
participant stoichiometry: PARTICIPANT STOICHIOMETRY re24 520
participant stoichiometry: PARTICIPANT STOICHIOMETRY re24 521
participant stoichiometry: PARTICIPANT STOICHIOMETRY re24 519
participant stoichiometry: PARTICIPANT STOICHIOMETRY re24 517
participant stoichiometry: PARTICIPANT STOICHIOMETRY re24 518
left: Complex (Oxytocin/Oxytocin Receptor/ G-Protein/GDP)
left: GTP
interaction type: DISSOCIATION
right: Complex (Oxytocin/Oxytocin Receptor)
right: GDP
right: Complex (GTP/G-Protein)

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
type: ProteinReference
xref: PTHR10336:SF173
xref: uniprot P10686 80
organism: Rattus norvegicus

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
type: ProteinReference
xref: PTHR10336:SF12
xref: uniprot P10687 81
organism: Rattus norvegicus

uniprot R4GKD1 487
type: UnificationXref
id: R4GKD1
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot Q90Z40 479
organism: Danio rerio

uniprot P05129 273
type: UnificationXref
id: P05129
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma
type: ProteinReference
xref: PTHR10336:SF25
xref: uniprot A0A1D5QLW6 11
organism: Macaca mulatta

uniprot F6ZC55 59
type: UnificationXref
id: F6ZC55
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
type: ProteinReference
xref: uniprot Q8R3B1 131
xref: PTHR10336:SF80
organism: Mus musculus

Protein kinase C-like 1
type: ProteinReference
xref: PTHR24356:SF347
xref: uniprot P34722 287
organism: Caenorhabditis elegans

uniprot E2RGI5 335
type: UnificationXref
id: E2RGI5
db: uniprot

EGL-30
type: ProteinReference
xref: PTHR10218:SF329
xref: uniprot G5EGU1 383
organism: Caenorhabditis elegans

uniprot H2QZN8 389
type: UnificationXref
id: H2QZN8
db: uniprot

uniprot Q9W1I8 233
type: UnificationXref
id: Q9W1I8
db: uniprot

Phosphoinositide phospholipase C
type: ProteinReference
xref: uniprot F7E2P1 63
organism: Monodelphis domestica

Protein kinase C zeta type
type: ProteinReference
xref: uniprot Q05513 299
xref: PTHR24356:SF170
organism: Homo sapiens

Guanine nucleotide-binding protein subunit beta-4
type: ProteinReference
xref: uniprot F6ZIZ9 361
organism: Macaca mulatta

TRIGGER
type: Control
xref: TRIGGER
controlled: TRANSPORT_LEFT__Ca2_PLUS_-RIGHT__Ca2_PLUS_-_re17
control type: ACTIVATION
controller: Ca2+ channel

uniprot P29992 409
type: UnificationXref
id: P29992
db: uniprot

Protein kinase C
type: ProteinReference
xref: PTHR24356:SF162
xref: uniprot F7H3B3 264
organism: Macaca mulatta

AGAP012252-PA (Fragment)
type: ProteinReference
xref: uniprot Q7Q042 306
xref: PTHR24356:SF390
organism: Anopheles gambiae

uniprot F6PGC8 349
type: UnificationXref
id: F6PGC8
db: uniprot

Protein kinase C delta type
type: ProteinReference
xref: PTHR24356:SF365
xref: uniprot H9EU39 269
organism: Macaca mulatta

uniprot Q9CXP8 480
type: UnificationXref
id: Q9CXP8
db: uniprot

t-SNARE protein aex-4
type: ProteinReference
xref: uniprot G5EEN8 177
organism: Caenorhabditis elegans

Ca2+ channel
type: Protein
feature: ACTIVE 146
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=PROTEIN

uniprot H2Q3W7 386
type: UnificationXref
id: H2Q3W7
db: uniprot

PARTICIPANT STOICHIOMETRY re12 532
type: Stoichiometry
physical entity: Oxytocin
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY re12 531
type: Stoichiometry
physical entity: Oxytocin
stoichiometric coefficient: 1.0

uniprot F6XYX9 171
type: UnificationXref
id: F6XYX9
db: uniprot

uniprot Q56W08 111
type: UnificationXref
id: Q56W08
db: uniprot

Protein kinase C alpha type
type: ProteinReference
xref: uniprot P17252 282
xref: PTHR24356:SF193
organism: Homo sapiens

Vesicle-associated membrane protein 1
type: ProteinReference
xref: PTHR45701:SF1
xref: uniprot P23763 191
organism: Homo sapiens

uniprot P05128 272
type: UnificationXref
id: P05128
db: uniprot

uniprot Q05655 300
type: UnificationXref
id: Q05655
db: uniprot

G protein subunit beta 3
type: ProteinReference
xref: uniprot H2R3A6 390
organism: Pan troglodytes

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma
type: ProteinReference
xref: uniprot Q9VXH3 143
organism: Drosophila melanogaster

Oxytocin receptor
type: ProteinReference
xref: PTHR24241:SF89
xref: uniprot P97926 153
organism: Mus musculus

Protein kinase C
type: ProteinReference
xref: uniprot A0A2R8QJ48 239
xref: PTHR24356:SF192
organism: Danio rerio

uniprot Q17QQ3 210
type: UnificationXref
id: Q17QQ3
db: uniprot

STATE_TRANSITION
type: InteractionVocabulary

TRANSPORT
type: InteractionVocabulary

uniprot P34885 288
type: UnificationXref
id: P34885
db: uniprot

HETERODIMER_ASSOCIATION_LEFT__Complex__Oxytocin_Receptor_G_Protein__GDP_-_Oxytocin-RIGHT__Complex__Oxytocin_Oxytocin_Receptor__G_Protein_GDP_-_re23
type: ComplexAssembly
spontaneous: true
conversion direction: LEFT_TO_RIGHT
xref: HETERODIMER ASSOCIATION
participant stoichiometry: PARTICIPANT STOICHIOMETRY re23 524
participant stoichiometry: PARTICIPANT STOICHIOMETRY re23 522
participant stoichiometry: PARTICIPANT STOICHIOMETRY re23 523
left: Oxytocin
left: Complex (Oxytocin Receptor/G-Protein/ GDP)
interaction type: HETERODIMER_ASSOCIATION
right: Complex (Oxytocin/Oxytocin Receptor/ G-Protein/GDP)

uniprot F1A421 341
type: UnificationXref
id: F1A421
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
type: ProteinReference
xref: PTHR10336:SF25
xref: uniprot Q8CIH5 124
organism: Mus musculus

CATALYSIS
type: Catalysis
controlled: DISSOCIATION_LEFT__PIP2-RIGHT__IP3-_DAG-_re6
controller: PLC beta

uniprot A0A3Q1LYB4 158
type: UnificationXref
id: A0A3Q1LYB4
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
type: ProteinReference
xref: uniprot A0A1D5Q4D0 10
xref: PTHR10336:SF11
organism: Macaca mulatta

uniprot B8JLJ7 325
type: UnificationXref
id: B8JLJ7
db: uniprot

Phosphoinositide phospholipase C
type: ProteinReference
xref: PTHR10336:SF51
xref: uniprot A0A096MJW8 4
organism: Rattus norvegicus

ncbitaxon 7227 86
type: UnificationXref
id: 7227
db: ncbitaxon

uniprot A0A2I3RKF6 14
type: UnificationXref
id: A0A2I3RKF6
db: uniprot

uniprot Q0V7N0 207
type: UnificationXref
id: Q0V7N0
db: uniprot

ncbitaxon 9544 9
type: UnificationXref
id: 9544
db: ncbitaxon

G-Protein
type: Protein
entity reference: G-Protein
feature: COMPLEX PARTICIPANT BINDING FEATURE s4 sa4 495
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=PROTEIN

GTP
type: SmallMolecule
cellular location: mammary cells, uterus, also some brain cells entry of Ca2 PLUS does not cause muscle contraction in neurons c8
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot F7AQR3 362
type: UnificationXref
id: F7AQR3
db: uniprot

uniprot P63213 436
type: UnificationXref
id: P63213
db: uniprot

uniprot Q6PC54 221
type: UnificationXref
id: Q6PC54
db: uniprot

uniprot P28867 286
type: UnificationXref
id: P28867
db: uniprot

Protein kinase C theta type
type: ProteinReference
xref: uniprot Q04759 298
xref: PTHR24356:SF181
organism: Homo sapiens

Protein kinase C
type: ProteinReference
xref: uniprot A0A3Q1MSP9 241
xref: PTHR24356:SF170
organism: Bos taurus

uniprot F6VVA6 55
type: UnificationXref
id: F6VVA6
db: uniprot

uniprot F1M7Y5 250
type: UnificationXref
id: F1M7Y5
db: uniprot

uniprot P13677 279
type: UnificationXref
id: P13677
db: uniprot

uniprot Q91UZ1 132
type: UnificationXref
id: Q91UZ1
db: uniprot

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II
type: ProteinReference
xref: uniprot P25455 90
organism: Drosophila melanogaster

Syntaxin 3A
type: ProteinReference
xref: PTHR19957:SF34
xref: uniprot Q6PHV0 222
organism: Danio rerio

uniprot A0A3Q2U0G2 23
type: UnificationXref
id: A0A3Q2U0G2
db: uniprot

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F7ERP8 371
organism: Ornithorhynchus anatinus

Guanine nucleotide-binding protein subunit gamma
type: ProteinReference
xref: uniprot F6VPY1 355
organism: Ornithorhynchus anatinus

Syntaxin 3
type: ProteinReference
xref: PTHR19957:SF34
xref: uniprot F7EPG4 175
organism: Ornithorhynchus anatinus

uniprot A0A1D5QDW1 154
type: UnificationXref
id: A0A1D5QDW1
db: uniprot

uniprot P10895 84
type: UnificationXref
id: P10895
db: uniprot

Guanine nucleotide-binding protein subunit beta
type: ProteinReference
xref: uniprot P36408 412
organism: Dictyostelium discoideum

PARTICIPANT STOICHIOMETRY re23 524
type: Stoichiometry
physical entity: Complex (Oxytocin/Oxytocin Receptor/ G-Protein/GDP)
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY re23 522
type: Stoichiometry
physical entity: Complex (Oxytocin Receptor/G-Protein/ GDP)
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY re23 523
type: Stoichiometry
physical entity: Oxytocin
stoichiometric coefficient: 1.0

uniprot P83351 205
type: UnificationXref
id: P83351
db: uniprot

Oxytocin s12 sa10 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Oxytocin
stoichiometric coefficient: 1.0

uniprot A0A096MJW8 4
type: UnificationXref
id: A0A096MJW8
db: uniprot

uniprot G2HIJ9 176
type: UnificationXref
id: G2HIJ9
db: uniprot

uniprot P62872 427
type: UnificationXref
id: P62872
db: uniprot

uniprot P40977 93
type: UnificationXref
id: P40977
db: uniprot

uniprot A0A2I3T8F7 19
type: UnificationXref
id: A0A2I3T8F7
db: uniprot