Phosphatidylinositol 3-kinase catalytic subunit type 3
Mitogen-activated protein kinase kinase 1
ENTITY_REFERENCE_NOTES= Long Name: MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1 Synonym: MAPK/ERK KINASE 1,MAPKK1,MKK1,PROTEIN KINASE, MITOGEN-ACTIVATED, KINASE 1 Accession: P01162
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.MEK
Platelet-derived growth factor receptor-like protein
Mitogen-activated protein kinase kinase 2
SOS Ras/Rac guanine nucleotide exchange factor 1
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.Grb2
3-phosphoinositide dependent protein kinase 1
Ras-related and estrogen-regulated growth inhibitor
Dual specificity mitogen-activated protein kinase kinase 1
Signal transducer and activator of transcription
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
MAP kinase-interacting serine/threonine-protein kinase 1
Dual-specificity mitogen-activated protein kinase kinase 2
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.Jak
ENTITY_REFERENCE_NOTES= Long Name: Jak Synonym: Janus kinase Accession: P01155
Inhibitor of nuclear factor kappa B kinase subunit beta
ENTITY_REFERENCE_NOTES= Long Name: Phospholipase C, gamma Synonym: PLCG,PLCGamma,Phospholipase C-148 Accession: P01171
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.PLC_gamma_
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit
Phosphatidylinositol 3-kinase regulatory subunit gamma
StAR-related lipid transfer domain-containing 8
A-Raf proto-oncogene, serine/threonine kinase
MAP kinase-interacting serine/threonine-protein kinase 2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma
Conserved helix-loop-helix ubiquitous kinase
Inositol 1,4,5-trisphosphate receptor type 1
SLIT-ROBO Rho GTPase activating protein 3
SLIT-ROBO Rho GTPase-activating protein 2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
SAM pointed domain containing ETS transcription factor
Website http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd
Platelet derived growth factor receptor like
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.PI3K
ENTITY_REFERENCE_NOTES= Long Name: PHOSPHATIDYLINOSITOL 3-KINASE, CATALYTIC, ALPHA Synonym: Synonym not specified Accession: P01168
SLIT-ROBO Rho GTPase-activating protein 3
Mitogen-activated protein kinase-activated protein kinase 2
Phosphoinositide-3-kinase regulatory subunit 1
Phosphoinositide-3-kinase regulatory subunit 5
Vav guanine nucleotide exchange factor 1
Signal transducer and activator of transcription 5B
Inhibitor of nuclear factor kappa-B kinase subunit beta
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.PDGF
ENTITY_REFERENCE_NOTES= Long Name: PDGF Synonym: Platelet-derived growth factor Accession: P01170
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.c-fos
ENTITY_REFERENCE_NOTES= Long Name: c-fos Synonym: Cellular oncogene fos,Proto-oncogene protein c-fos Accession: P01145
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.Vav
ENTITY_REFERENCE_NOTES= Long Name: Vav Synonym: family of guanine nucleotide exchange factors for Rho family GTPases Accession: P01169
3-phosphoinositide-dependent protein kinase 1
GA repeat binding protein, alpha (Predicted)
Inositol 1,4,5-trisphosphate receptor type 3
SHC (Src homology 2 domain containing) transforming protein 1
B-Raf proto-oncogene, serine/threonine kinase
Mitogen-activated protein kinase kinase kinase 4
Inositol 1,4,5-trisphosphate receptor itr-1
Platelet-derived growth factor alpha polypeptide a
Putative ribosomal protein S6 kinase alpha-1
Raf-1 proto-oncogene, serine/threonine kinase
Non-specific serine/threonine protein kinase
ENTITY_REFERENCE_NOTES= Long Name: Ras Synonym: Synonym not specified Accession: P01154
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.Ras
Inositol 1,4,5-trisphosphate receptor type 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
ETS domain-containing transcription factor ERF
Complex (PDGF receptor A/PDGF receptor B)
GA binding protein transcription factor subunit alpha
Upstream transcription factor 2, c-fos interacting
Vav guanine nucleotide exchange factor 3
SLIT-ROBO Rho GTPase activating protein 1
Inhibitor of nuclear factor kappa-B kinase subunit alpha
-Ha-ras Harvey rat sarcoma viral oncogene homolog, like
Friend leukemia integration 1 transcription factor
SAM pointed domain containing ets transcription factor
Phosphatidylinositol 3-kinase regulatory subunit beta
Phosphatidylinositol 3-kinase regulatory subunit alpha
Dual specificity mitogen-activated protein kinase kinase 2
ETS proto-oncogene 1, transcription factor
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
3-phosphoinositide-dependent protein kinase 1 and 2
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.PDK1/2
ENTITY_REFERENCE_NOTES= Long Name: 3'-Phosphoinositide-dependent protein kinase1/2 Synonym: PDK1,PDPK1 Accession: P01164
SLIT-ROBO Rho GTPase-activating protein 1
SOS Ras/Rho guanine nucleotide exchange factor 2
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Raf-1 proto-oncogene, serine/threonine kinase a
RAB11B, member RAS oncogene family, gene 1
Signal transducer and transcription activator
Signal transducer and activator of transcription 4
Signal transducers and activators of transcription
ENTITY_REFERENCE_NOTES= Long Name: STAT Synonym: STAT1,STAT2,STAT3,STAT4,STAT5A,STAT5B,STAT6,Signal transducers and activators of transcription Accession: P01173
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.STAT
Mitogen-activated protein kinase-interacting serine/threonine kinase1/2
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.MNK1/2
ENTITY_REFERENCE_NOTES= Long Name: MNK1/2 Synonym: MAPK-interacting kinase 1/2,MKNK1,MNK2 Accession: P01149
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.ION_CHANNEL.IP3_br_receptor
ENTITY_REFERENCE_NOTES= Long Name: IP3 receptor Synonym: INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR Accession: P01160
Signal transducer and activator of transcription 3
Platelet-derived growth factor receptor beta
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.c-Jun
ENTITY_REFERENCE_NOTES= Long Name: c-Jun Synonym: Synonym not specified Accession: P01163
Platelet-derived growth factor subunit A
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.c-Myc
ENTITY_REFERENCE_NOTES= Long Name: c-Myc Synonym: Synonym not specified Accession: P01172
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.PKB
ENTITY_REFERENCE_NOTES= Long Name: PROTEIN KINASE B-BETA Synonym: AKT2,PKB,V-AKT MURINE THYMOMA VIRAL ONCOGENE HOMOLOG 2 Accession: P01151
Rho GTPase activating protein at 16F, isoform E
Putative glycogen synthase kinase-3 homolog
RAC-beta serine/threonine-protein kinase
SLIT-ROBO Rho GTPase-activating protein 1b
ENTITY_REFERENCE_NOTES= Long Name: ELK Synonym: MEMBER OF ETS ONCOGENE FAMILY Accession: P01140
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.ELK
Ras guanine nucleotide exchange factor P
Mitogen-activated protein kinase kinase kinase 2
RAS p21 protein activator (GTPase activating protein) 1
Platelet-derived growth factor subunit B
RAF proto-oncogene serine/threonine-protein kinase
ENTITY_REFERENCE_NOTES= Long Name: mTOR Synonym: FK506-BINDING PROTEIN 12-RAPAMYCIN COMPLEX-ASSOCIATED PROTEIN 1,FRAP,mTOR Accession: P01144
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.mTOR
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.RECEPTOR.PDGF_br_receptor A
ENTITY_REFERENCE_NOTES= Long Name: PDGF receptor A Synonym: PDGF receptor/CSF1 receptor family,PDGFR2 Accession: P01158
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.Raf
ENTITY_REFERENCE_NOTES= Long Name: MURINE LEUKEMIA VIRAL ONCOGENE HOMOLOG 1 Synonym: ONCOGENE RAF1 Accession: P01161
Fli-1 proto-oncogene, ETS transcription factor a
Phosphatidylinositol 3-kinase VPS34-like
Phosphoinositide 3-kinase regulatory subunit 5
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.PKC
ENTITY_REFERENCE_NOTES= Long Name: Protein kinase C Synonym: Synonym not specified Accession: P01150
Harvey rat sarcoma viral oncogene homolog
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
V-ets avian erythroblastosis virus E26 oncogene homolog
V-fos FBJ murine osteosarcoma viral oncogene homolog
Signal transducer and activator of transcription 2
SH2 homology domain containing transforming protein
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.Shc
ENTITY_REFERENCE_NOTES= Long Name: Shc Synonym: Synonym not specified Accession: P01175
Dual specificity mitogen-activated protein kinase kinase mek-2
Raf homolog serine/threonine-protein kinase Raf
Platelet-derived growth factor receptor alpha
MODEL_NOTES=Panther Pathway: P00047 Platelet derived growth factor (PDGF) plays a critical role in cellular proliferation and development. PDGF signaling is initiated upon binding of PDGF to the PDGF receptor complex. The PDGF receptors belong to the family of receptor protein tyrosine kinases (RPTK). Upon ligand binding, the receptors chains trans-phosphorylate each other, resulting in recruitment of adaptor molecules via SH2 domains and leading to phosphorylation of other cellular proteins. Medline=1339664 Medline=7888178 Medline=973976 Website=http://www.biocarta.com/pathfiles/h_pdgfPathway.asp PMID: 1339664 PMID: 7888178 PMID: 973976
SLIT-ROBO Rho GTPase-activating protein 2 isoform a
Phosphoinositide-3-kinase regulatory subunit 3
Rho GTPase activating protein 26 (Predicted)
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.MAPKAPK2
ENTITY_REFERENCE_NOTES= Long Name: MAPKAPK2 Synonym: MAPKAP kinase 2,MAPKAPK2 Accession: P01157
Signal transducer and activator of transcription 1-alpha/beta
Signal transducer and activator of transcription 5A
Ras guanine nucleotide exchange factor R
Signal transducer and activator of transcription 1
Signal transducer and activator of transcription 6
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.Ikk
ENTITY_REFERENCE_NOTES= Long Name: cytokine-responsive IkappaB kinase Synonym: IKK,IkappaB kinase Accession: P01146
Glycogen synthase kinase-3 beta isoform 1
Guanine nucleotide exchange factor VAV2 isoform 1
Phosphoinositide-3-kinase regulatory subunit 2
Rho GTPase activating protein 4, isoform CRA_a
Serine/threonine-protein kinase RIM11/MSD1
Signal transducer and transcription activator 6
RAS-like, estrogen-regulated, growth-inhibitor
Ras guanine nucleotide exchange factor B
Ras guanine nucleotide exchange factor A
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.Nck
ENTITY_REFERENCE_NOTES= Long Name: Nck Synonym: GRB4,MELANOMA NCK PROTEIN,NCK ADAPTOR PROTEIN Accession: P01147
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Ras guanine nucleotide exchange factor E
GA binding protein transcription factor, alpha subunit 60kDa
Extracellular signal-regulated kinase family
ENTITY_REFERENCE_NOTES= Long Name: Extracellular signal-regulated kinase family Synonym: ERK,Maturation- or mitogen-activated protein (MAP) kinase family Accession: P01143
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.ERK
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.Rho
ENTITY_REFERENCE_NOTES= Long Name: GTPase-activating protein Rho Synonym: Rho-GTPase-activating protein,RhoGAP Accession: P01174
Fli-1 proto-oncogene, ETS transcription factor
RAS like estrogen regulated growth inhibitor
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
ETS domain-containing protein Elk-4 isoform a
RAB11B, member RAS oncogene family, gene 2
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.GSK3
ENTITY_REFERENCE_NOTES= Long Name: GSK3 Synonym: GLYCOGEN SYNTHASE KINASE 3 Accession: P01153
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma plc-3
MAP kinase interacting serine/threonine kinase 2
StAR-related lipid transfer domain-containing 13
Dual specificity mitogen-activated protein kinase kinase dSOR1
Fos proto-oncogene, AP-1 transcription factor subunit
ENTITY_REFERENCE_NOTES= Long Name: PDGF receptor B Synonym: PDGFRB,PDGFR,PDGFR1 Accession: P01156
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.RECEPTOR.PDGF_br_receptor B
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.Ets
ENTITY_REFERENCE_NOTES= Long Name: Ets Synonym: Ets transcription factors Accession: P01167
Inositol 1,4,5-trisphosphate receptor type 1 isoform 3
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.SRF
ENTITY_REFERENCE_NOTES= Long Name: SRF Synonym: C-FOS SERUM RESPONSE ELEMENT-BINDING FACTOR,SERUM RESPONSE FACTOR Accession: P01165
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
SAM pointed domain-containing Ets transcription factor
GTPase regulator associated with FAK, isoform G
Chromosomal serine/threonine-protein kinase JIL-1
ENTITY_REFERENCE_NOTES= Long Name: p90RSK Synonym: RIBOSOMAL PROTEIN S6 KINASE,RPS6KA1,RSK1,p90RSK Accession: P01142
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.p90RSK
Vav guanine nucleotide exchange factor 2
MAP kinase-interacting serine/threonine-protein kinase 2 isoform 2
FBJ murine osteosarcoma viral oncogene homolog
Raf homolog serine/threonine-protein kinase
ETS-related transcription factor Elf-2 isoform 1
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.RasGAP
ENTITY_REFERENCE_NOTES= Long Name: Ras GTPase Activity Protein Synonym: RasGAP Accession: P01152
SLIT-ROBO Rho GTPase activating protein 2
Platelet-derived growth factor A chain long form
ENTITY_REFERENCE_NOTES= Long Name: Son of Sevenless Synonym: SON OF SEVENLESS,SOS Accession: P01159
ENTITY_REFERENCE_ID_DESC=PDGF signaling pathway.PROTEIN.GENERIC.SOS
Jun proto-oncogene, AP-1 transcription factor subunit
Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 1
Ras guanine nucleotide exchange factor Y