Insulin-like growth factor-binding protein 1
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.FOXO
ENTITY_REFERENCE_NOTES= Long Name: FOXO Synonym: DAF-16,DAF_16,FKHRL1,FKHRL2,FKHRL3,FKHRL4,Forkhead box subgroup "O" protein,Forkhead transcription factor Accession: P01198
Guanine nucleotide-binding protein G(T) subunit gamma-T1
Guanine nucleotide-binding protein (G protein), alpha 11b (Gq class)
SOS Ras/Rac guanine nucleotide exchange factor 1
3-phosphoinositide dependent protein kinase 1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Guanine nucleotide-binding protein subunit beta-5a
Non-specific serine/threonine protein kinase
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit
ENTITY_REFERENCE_NOTES= Long Name: Cyclin d Synonym: PRAD1: parathyroid adenomatosis 1 Accession: G01546
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.GENE.GENE.Cyclin d
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.Ras
Guanine nucleotide-binding protein subunit alpha-11
Phosphatidylinositol 3-kinase regulatory subunit gamma
ENTITY_REFERENCE_NOTES= Long Name: p101 Synonym: Class IB PI3 Kinase,Class IB phosphoinositol 3-kinase Accession: P01203
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.p101
3-phosphoinositide-dependent protein kinase 1
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.PDK1
ENTITY_REFERENCE_NOTES= Long Name: PDK1 Synonym: 3-phosphoinositide dependent kinase 1 Accession: P01196
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
Guanine nucleotide-binding protein G(q) subunit alpha
Guanine nucleotide-binding protein G(i) subunit alpha-1
Guanine nucleotide-binding protein G(t) subunit alpha-2
ENTITY_REFERENCE_NOTES= Long Name: SOS Synonym: Son of sevenless Accession: P01185
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.SOS
ENTITY_REFERENCE_NOTES= Long Name: scl-1 Synonym: Synonym not specified Accession: G01545
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.GENE.GENE.scl-1
ENTITY_REFERENCE_NOTES= Long Name: p110 Synonym: Class IA PI3K catalytic subunit Accession: P01192
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.p110
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.G_sub__alpha_
Guanine nucleotide-binding protein G(i) subunit alpha-2
Phosphoinositide-3-kinase regulatory subunit 5
Guanine nucleotide-binding protein subunit beta-1
Guanine nucleotide-binding protein (G protein), alpha 11 (Gq class)
Guanine nucleotide-binding protein G(k) subunit alpha
Guanine nucleotide-binding protein subunit beta-4
Guanine nucleotide-binding protein subunit alpha-14
Complex (GPCR ligand/GPCR/ Galpha/Gbetagamma)
ENTITY_REFERENCE_NOTES= Long Name: Grb2 Synonym: Growth-factor-receptor-bound protein 2 Accession: P01178
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.Grb2
3-phosphoinositide-dependent protein kinase 1, active
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.PDK1 ACT
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.RECEPTOR.GPCR
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18
-Ha-ras Harvey rat sarcoma viral oncogene homolog, like
Phosphatidylinositol 3-kinase regulatory subunit beta
Phosphatidylinositol 3-kinase regulatory subunit alpha
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
ENTITY_REFERENCE_NOTES= Long Name: JAK Synonym: JAK1,JAK2,JAK3,Janus kinase Accession: P01176
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.JAK
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
SOS Ras/Rho guanine nucleotide exchange factor 2
Probable type I inositol 1,4,5-trisphosphate 5-phosphatase
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
RAC-gamma serine/threonine-protein kinase
Guanine nucleotide-binding protein subunit gamma
Inositol polyphosphate phosphatase like 1
Insulin-like growth factor binding protein-1
ENTITY_REFERENCE_NOTES= Long Name: GADD45 Synonym: Synonym not specified Accession: G01544
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.GENE.GENE.GADD45
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.PTEN
ENTITY_REFERENCE_NOTES= Long Name: PTEN Synonym: DAF-18,MMAC,TEP1,mutated in multiple advanced cancers,phosphatase and tensin homolog deleted on chromosome ten,tumour growth factor-beta-regulated and epithelial cell enriched phosphatase Accession: P01189
ENTITY_REFERENCE_NOTES= Long Name: Activated p110 Synonym: Activated Class IA PI3K catalytic subunit Accession: P01177
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.P110ACT
ENTITY_REFERENCE_NOTES= Long Name: IGFBP1 Synonym: Synonym not specified Accession: G01543
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.GENE.GENE.IGFBP1
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Guanine nucleotide-binding protein (G protein), q polypeptide
RAC-alpha serine/threonine-protein kinase
RAC-beta serine/threonine-protein kinase
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
Website http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd
Complex (ITK ligand/Int Tyr Kin/ p85/p110)
Phosphoinositide 3-kinase regulatory subunit 5
Guanine nucleotide-binding protein (G protein), alpha-inhibiting activity polypeptide 1
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.p85
ENTITY_REFERENCE_NOTES= Long Name: p85 Synonym: Class IA PI3K regulatory subunit Accession: P01202
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2
Guanine nucleotide-binding protein subunit beta
Phosphoinositide-3-kinase regulatory subunit 1
Guanine nucleotide-binding protein subunit beta-5
Type I inositol 1,4,5-trisphosphate 5-phosphatase
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.GSK3
ENTITY_REFERENCE_NOTES= Long Name: GSK3 Synonym: Glycogen synthase kinase 3 Accession: P01181
Growth arrest and DNA damage-inducible protein GADD45 alpha
MODEL_NOTES=Panther Pathway: P00048 Phosphoinositide 3-kinase (PI3K) catalyzes the production of phosphatidylinositol-3,4,5-trisphosphate, which is involved in several crucial biological processes, including cell survival, regulation of gene expression and cell metabolism, and cytoskeletal rearrangements. The PI3K pathway is also implicated in several human diseases, including diabetes and cancer. Medline=12040186 Medline=12062096 Medline=12646949 Medline=12829733 Medline=12871670 PMID: 12040186 PMID: 12062096 PMID: 12646949 PMID: 12829733 PMID: 12871670
Phosphoinositide-3-kinase regulatory subunit 3
Guanine nucleotide-binding protein subunit beta-2
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.IRS
ENTITY_REFERENCE_NOTES= Long Name: Insulin Receptor Substrate Synonym: IRS,chico,ist-1 Accession: P01193
Glycogen synthase kinase-3 beta isoform 1
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.S6K
ENTITY_REFERENCE_NOTES= Long Name: S6K Synonym: p70 S6 kinase Accession: P01194
Phosphoinositide-3-kinase regulatory subunit 2
Guanine nucleotide-binding protein G(K) subunit alpha
SH2 domain-containing inositol 5-phosphatase
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.SHIP
ENTITY_REFERENCE_NOTES= Long Name: SHIP Synonym: SH2-domain-containing inositol phosphatase Accession: P01200
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.RECEPTOR.IR
ENTITY_REFERENCE_NOTES= Long Name: Insulin Receptor Synonym: DAF-2,IGF-1R,IR,IRR,Insulin Growth Factor 1 Receptor,Insulin-receptor-like receptor Accession: P01187
Guanine nucleotide-binding protein (G protein), beta 5
Guanine nucleotide-binding protein (G protein), alpha-inhibiting activity polypeptide 2b
Guanine nucleotide-binding protein (G protein), alpha 14
ENTITY_REFERENCE_NOTES= Long Name: NOS Synonym: Nitric oxide synthase Accession: P01205
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.NOS
Guanine nucleotide-binding protein beta subunit
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.PKB
ENTITY_REFERENCE_NOTES= Long Name: PKB Synonym: Akt,Protein kinase B Accession: P01179
Guanine nucleotide binding protein, beta subunit
ENTITY_REFERENCE_NOTES= Long Name: 14-3-3 Synonym: GF14 Accession: P01206
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.14-3-3
Guanine nucleotide-binding protein (G protein), alpha-inhibiting activity polypeptide a
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.G_sub__beta__gamma_
ENTITY_REFERENCE_NOTES= Long Name: Gbetagamma Synonym: Heterotrimeric G-protein beta gamma subunit Accession: P01188
ENTITY_REFERENCE_NOTES= Long Name: Caspase-9 Synonym: Apaf-3,Cysteine containing aspartate specific protease 9,Cysteine-containing aspartate specific protease 9,ICE-LAP6,Mch6 Accession: P01197
ENTITY_REFERENCE_ID_DESC=PI3 kinase pathway.PROTEIN.GENERIC.Caspase-9
Complex (JAK Ligand/JAK receptor/ p85/p110)
Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 1