Aromatic-amino-acid aminotransferase
type: ProteinReference
xref: uniprot P04693 43
organism: Escherichia coli

ncbitaxon 208964 46
type: UnificationXref
id: 208964
db: ncbitaxon

Putative prephenate dehydratase
type: ProteinReference
xref: uniprot P32452 10
organism: Saccharomyces cerevisiae

Chorismate mutase
type: ProteinReference
xref: uniprot Q7S8R4 37
organism: Neurospora crassa

uniprot O14361 2
type: UnificationXref
id: O14361
db: uniprot

Gloeobacter violaceus
type: BioSource
xref: ncbitaxon 251221 13

Chorismate mutase
type: ProteinReference
xref: P03100
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: Chorismate mutase Synonym: Synonym not specified Accession: P03100
comment: ENTITY_REFERENCE_ID_DESC=Phenylalanine biosynthesis.PROTEIN.GENERIC.Chorismate mutase
member entity reference: Chorismate mutase
member entity reference: Chorismate mutase AroH
member entity reference: Chorismate mutase 2
member entity reference: Chorismate mutase 1, chloroplastic
member entity reference: Chorismate mutase 3, chloroplastic
member entity reference: Probable chorismate mutase

uniprot P32452 10
type: UnificationXref
id: P32452
db: uniprot

Arogenate dehydratase/prephenate dehydratase 2, chloroplastic
type: ProteinReference
xref: uniprot Q9SSE7 26
organism: Arabidopsis thaliana

Prephenate dehydratase
type: ProteinReference
xref: P03099
comment: ENTITY_REFERENCE_NOTES= Long Name: Prephenate dehydratase Synonym: Synonym not specified Accession: P03099
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Phenylalanine biosynthesis.PROTEIN.GENERIC.Prephenate dehydratase
member entity reference: p-protein (PheA)
member entity reference: Prephenate dehydratase
member entity reference: Arogenate dehydratase 3, chloroplastic
member entity reference: Putative prephenate dehydratase
member entity reference: Bifunctional prephenate dehydratase/chorismate mutase
member entity reference: Arogenate dehydratase/prephenate dehydratase 6, chloroplastic
member entity reference: Chorismate mutase/prephenate dehydratase
member entity reference: Arogenate dehydratase/prephenate dehydratase 2, chloroplastic
member entity reference: Arogenate dehydratase 5, chloroplastic
member entity reference: Bifunctional chorismate mutase/prephenate dehydratase
member entity reference: Arogenate dehydratase 4, chloroplastic

Putative prephenate dehydratase
type: ProteinReference
xref: uniprot O14361 2
organism: Schizosaccharomyces pombe

uniprot O67085 6
type: UnificationXref
id: O67085
db: uniprot

Prephenate dehydratase
type: Protein
entity reference: Prephenate dehydratase
comment: SPECIES_TYPE=PROTEIN

Bacillus subtilis
type: BioSource
xref: ncbitaxon 224308 9

uniprot Q9S7H4 42
type: UnificationXref
id: Q9S7H4
db: uniprot

uniprot Q9ZBX0 29
type: UnificationXref
id: Q9ZBX0
db: uniprot

ncbitaxon 83333 44
type: UnificationXref
id: 83333
db: ncbitaxon

uniprot P32178 34
type: UnificationXref
id: P32178
db: uniprot

ncbitaxon 251221 13
type: UnificationXref
id: 251221
db: ncbitaxon

STATE_TRANSITION_LEFT__chorismate-RIGHT__prephenate-_r1
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 55
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 56
left: chorismate
interaction type: STATE_TRANSITION
right: prephenate

Thermotoga maritima
type: BioSource
xref: ncbitaxon 243274 28

STATE_TRANSITION_LEFT__glutamate-_phenylpyruvate-RIGHT__ketolgutarate-_phenylalanine-_r3
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 48
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 49
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 50
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 47
left: phenylpyruvate
left: glutamate
interaction type: STATE_TRANSITION
right: phenylalanine
right: ketolgutarate

uniprot Q9RV82 23
type: UnificationXref
id: Q9RV82
db: uniprot

ncbitaxon 3702 5
type: UnificationXref
id: 3702
db: ncbitaxon

Bifunctional prephenate dehydratase/chorismate mutase
type: ProteinReference
xref: uniprot Q8F6P7 18
organism: Leptospira interrogans

uniprot Q8TL89 20
type: UnificationXref
id: Q8TL89
db: uniprot

Arogenate dehydratase 4, chloroplastic
type: ProteinReference
xref: uniprot O22241 4
organism: Arabidopsis thaliana

ncbitaxon 243090 15
type: UnificationXref
id: 243090
db: ncbitaxon

Saccharomyces cerevisiae
type: BioSource
xref: ncbitaxon 559292 11

Prephenate dehydratase
type: ProteinReference
xref: uniprot Q8A0T5 16
organism: Bacteroides thetaiotaomicron

Methanosarcina acetivorans
type: BioSource
xref: ncbitaxon 188937 21

Aromatic amino acid aminotransferase
type: ProteinReference
xref: P03101
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: Aromatic amino acid aminotransferase Synonym: Synonym not specified Accession: P03101
comment: ENTITY_REFERENCE_ID_DESC=Phenylalanine biosynthesis.PROTEIN.GENERIC.Aromatic amino acid_br_aminotransferase
member entity reference: Aromatic-amino-acid aminotransferase
member entity reference: Aspartate aminotransferase

ncbitaxon 284812 3
type: UnificationXref
id: 284812
db: ncbitaxon

Chorismate mutase
type: Protein
entity reference: Chorismate mutase
comment: SPECIES_TYPE=PROTEIN

phenylpyruvate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q8F6P7 18
type: UnificationXref
id: Q8F6P7
db: uniprot

P03099
type: UnificationXref
id: P03099
db: PANTHER Pathway Component

Probable chorismate mutase
type: ProteinReference
xref: uniprot O13739 32
organism: Schizosaccharomyces pombe

uniprot Q7S8R4 37
type: UnificationXref
id: Q7S8R4
db: uniprot

Bifunctional chorismate mutase/prephenate dehydratase
type: ProteinReference
xref: uniprot O67085 6
organism: Aquifex aeolicus

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__chorismate-RIGHT__prephenate-_r1
controller: Chorismate mutase

ncbitaxon 243274 28
type: UnificationXref
id: 243274
db: ncbitaxon

Aquifex aeolicus
type: BioSource
xref: ncbitaxon 224324 7

Prephenate dehydratase
type: ProteinReference
xref: uniprot P21203 8
organism: Bacillus subtilis

Chorismate mutase
type: ProteinReference
xref: uniprot Q9S238 41
organism: Streptomyces coelicolor

STATE_TRANSITION_LEFT__prephenate-RIGHT__H2O-_CO2-_phenylpyruvate-_r2
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 51
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 53
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 52
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 54
left: prephenate
interaction type: STATE_TRANSITION
right: H2O
right: phenylpyruvate
right: CO2

Prephenate dehydratase
type: ProteinReference
xref: uniprot Q9ZBX0 29
organism: Streptomyces coelicolor

Neurospora crassa
type: BioSource
xref: ncbitaxon 367110 38

ncbitaxon 189518 19
type: UnificationXref
id: 189518
db: ncbitaxon

Chorismate mutase/prephenate dehydratase
type: ProteinReference
xref: uniprot Q9RV82 23
organism: Deinococcus radiodurans

H2O
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Bacteroides thetaiotaomicron
type: BioSource
xref: ncbitaxon 226186 17

uniprot Q9ZUY3 31
type: UnificationXref
id: Q9ZUY3
db: uniprot

Arogenate dehydratase/prephenate dehydratase 6, chloroplastic
type: ProteinReference
xref: uniprot Q9SGD6 25
organism: Arabidopsis thaliana

uniprot Q7UMM1 39
type: UnificationXref
id: Q7UMM1
db: uniprot

Schizosaccharomyces pombe
type: BioSource
xref: ncbitaxon 284812 3

glutamate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__glutamate-_phenylpyruvate-RIGHT__ketolgutarate-_phenylalanine-_r3
controller: Aromatic amino acid aminotransferase

PANTHER Pathway P02765 1
type: UnificationXref
id: P02765
db: PANTHER Pathway

Chorismate mutase
type: ProteinReference
xref: uniprot Q7UMM1 39
organism: Rhodopirellula baltica

Rhodopirellula baltica
type: BioSource
xref: ncbitaxon 243090 15

Streptomyces coelicolor
type: BioSource
xref: ncbitaxon 100226 30

uniprot P21203 8
type: UnificationXref
id: P21203
db: uniprot

Chorismate mutase AroH
type: ProteinReference
xref: uniprot P19080 33
organism: Bacillus subtilis

P03100
type: UnificationXref
id: P03100
db: PANTHER Pathway Component

P03101
type: UnificationXref
id: P03101
db: PANTHER Pathway Component

ncbitaxon 559292 11
type: UnificationXref
id: 559292
db: ncbitaxon

uniprot O22241 4
type: UnificationXref
id: O22241
db: uniprot

STATE_TRANSITION
type: RelationshipTypeVocabulary

STATE_TRANSITION
type: InteractionVocabulary

uniprot Q9SGD6 25
type: UnificationXref
id: Q9SGD6
db: uniprot

uniprot P72173 45
type: UnificationXref
id: P72173
db: uniprot

uniprot Q7NN89 12
type: UnificationXref
id: Q7NN89
db: uniprot

ketolgutarate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q9S238 41
type: UnificationXref
id: Q9S238
db: uniprot

ncbitaxon 188937 21
type: UnificationXref
id: 188937
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r1 55
type: Stoichiometry
physical entity: chorismate
stoichiometric coefficient: 1.0

Arogenate dehydratase 5, chloroplastic
type: ProteinReference
xref: uniprot Q9FNJ8 22
organism: Arabidopsis thaliana

CO2
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot O13739 32
type: UnificationXref
id: O13739
db: uniprot

Chorismate mutase 1, chloroplastic
type: ProteinReference
xref: uniprot P42738 35
organism: Arabidopsis thaliana

Leptospira interrogans
type: BioSource
xref: ncbitaxon 189518 19

PARTICIPANT STOICHIOMETRY r1 56
type: Stoichiometry
physical entity: prephenate
stoichiometric coefficient: 1.0

prephenate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Deinococcus radiodurans
type: BioSource
xref: ncbitaxon 243230 24

Chorismate mutase 3, chloroplastic
type: ProteinReference
xref: uniprot Q9C544 40
organism: Arabidopsis thaliana

Chorismate mutase 2
type: ProteinReference
xref: uniprot Q9S7H4 42
organism: Arabidopsis thaliana

uniprot Q7NH32 36
type: UnificationXref
id: Q7NH32
db: uniprot

Chorismate mutase AroH
type: ProteinReference
xref: uniprot Q7NH32 36
organism: Gloeobacter violaceus

phenylalanine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ncbitaxon 243230 24
type: UnificationXref
id: 243230
db: ncbitaxon

Prephenate dehydratase
type: ProteinReference
xref: uniprot Q7NN89 12
organism: Gloeobacter violaceus

Arogenate dehydratase 3, chloroplastic
type: ProteinReference
xref: uniprot Q9ZUY3 31
organism: Arabidopsis thaliana

uniprot Q9FNJ8 22
type: UnificationXref
id: Q9FNJ8
db: uniprot

PARTICIPANT STOICHIOMETRY r2 51
type: Stoichiometry
physical entity: prephenate
stoichiometric coefficient: 1.0

Chorismate mutase
type: ProteinReference
xref: uniprot P32178 34
organism: Saccharomyces cerevisiae

PARTICIPANT STOICHIOMETRY r2 52
type: Stoichiometry
physical entity: H2O
stoichiometric coefficient: 1.0

Arabidopsis thaliana
type: BioSource
xref: ncbitaxon 3702 5

Phenylalanine biosynthesis
type: Pathway
pathway component: STATE_TRANSITION_LEFT__chorismate-RIGHT__prephenate-_r1
pathway component: STATE_TRANSITION_LEFT__glutamate-_phenylpyruvate-RIGHT__ketolgutarate-_phenylalanine-_r3
pathway component: STATE_TRANSITION_LEFT__prephenate-RIGHT__H2O-_CO2-_phenylpyruvate-_r2
xref: PANTHER Pathway P02765 1
comment: MODEL_NOTES= The biosynthesis of the aromatic amino acid phenylalanine critical for protein biosynthesis. Website=www.biocyc.org/Ecoli/Pathways/ free text=Biochemistry (text) Voet and Voet

ncbitaxon 224308 9
type: UnificationXref
id: 224308
db: ncbitaxon

uniprot Q9C544 40
type: UnificationXref
id: Q9C544
db: uniprot

uniprot Q9SSE7 26
type: UnificationXref
id: Q9SSE7
db: uniprot

uniprot Q8A0T5 16
type: UnificationXref
id: Q8A0T5
db: uniprot

uniprot Q9WY02 27
type: UnificationXref
id: Q9WY02
db: uniprot

ncbitaxon 100226 30
type: UnificationXref
id: 100226
db: ncbitaxon

ncbitaxon 367110 38
type: UnificationXref
id: 367110
db: ncbitaxon

uniprot Q7UM30 14
type: UnificationXref
id: Q7UM30
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__prephenate-RIGHT__H2O-_CO2-_phenylpyruvate-_r2
controller: Prephenate dehydratase

Chorismate mutase/prephenate dehydratase
type: ProteinReference
xref: uniprot Q8TL89 20
organism: Methanosarcina acetivorans

uniprot P04693 43
type: UnificationXref
id: P04693
db: uniprot

uniprot P42738 35
type: UnificationXref
id: P42738
db: uniprot

Aspartate aminotransferase
type: ProteinReference
xref: uniprot P72173 45
organism: Pseudomonas aeruginosa

PARTICIPANT STOICHIOMETRY r3 49
type: Stoichiometry
physical entity: ketolgutarate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r3 47
type: Stoichiometry
physical entity: glutamate
stoichiometric coefficient: 1.0

Escherichia coli
type: BioSource
xref: ncbitaxon 83333 44

PARTICIPANT STOICHIOMETRY r3 48
type: Stoichiometry
physical entity: phenylpyruvate
stoichiometric coefficient: 1.0

ncbitaxon 224324 7
type: UnificationXref
id: 224324
db: ncbitaxon

ncbitaxon 226186 17
type: UnificationXref
id: 226186
db: ncbitaxon

uniprot P19080 33
type: UnificationXref
id: P19080
db: uniprot

Chorismate mutase/prephenate dehydratase
type: ProteinReference
xref: uniprot Q9WY02 27
organism: Thermotoga maritima

PARTICIPANT STOICHIOMETRY r2 54
type: Stoichiometry
physical entity: phenylpyruvate
stoichiometric coefficient: 1.0

Pseudomonas aeruginosa
type: BioSource
xref: ncbitaxon 208964 46

PARTICIPANT STOICHIOMETRY r2 53
type: Stoichiometry
physical entity: CO2
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r3 50
type: Stoichiometry
physical entity: phenylalanine
stoichiometric coefficient: 1.0

chorismate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Aromatic amino acid aminotransferase
type: Protein
entity reference: Aromatic amino acid aminotransferase
comment: SPECIES_TYPE=PROTEIN

p-protein (PheA)
type: ProteinReference
xref: uniprot Q7UM30 14
organism: Rhodopirellula baltica