Membrane primary amine oxidase
type: ProteinReference
xref: uniprot Q16853 32
organism: Homo sapiens

ncbitaxon 3702 19
type: UnificationXref
id: 3702
db: ncbitaxon

PTHR11699:SF211
type: RelationshipXref
id: PTHR11699:SF211
db: PANTHER Family
relationship type: By Homology

NADH
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Amine oxidase
type: ProteinReference
xref: uniprot E9Q745 8
organism: Mus musculus

uniprot O75106 24
type: UnificationXref
id: O75106
db: uniprot

Phenylacetaldehyde dehydrogenase
type: ProteinReference
xref: uniprot P80668 2
xref: PTHR11699:SF211
organism: Escherichia coli

H2O2
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

O2
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Bos taurus
type: BioSource
xref: ncbitaxon 9913 7

Macaca mulatta
type: BioSource
xref: ncbitaxon 9544 11

eco ECO:0000250 4
type: UnificationXref
id: ECO:0000250
db: eco

Amine oxidase
type: ProteinReference
xref: uniprot Q8L742 37
organism: Arabidopsis thaliana

Copper amine oxidase 1
type: ProteinReference
xref: uniprot Q9P7F2 40
organism: Schizosaccharomyces pombe

uniprot F7GP69 13
type: UnificationXref
id: F7GP69
db: uniprot

Mus musculus
type: BioSource
xref: ncbitaxon 10090 9

uniprot P36633 28
type: UnificationXref
id: P36633
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__NAD-_H2O-_phenylacetaldehyde-RIGHT__phenylacetate-_NADH-_r2
controller: Phenylacetaldehyde dehydrogenase

ncbitaxon 10090 9
type: UnificationXref
id: 10090
db: ncbitaxon

uniprot P46883 31
type: UnificationXref
id: P46883
db: uniprot

PARTICIPANT STOICHIOMETRY r1 52
type: Stoichiometry
physical entity: H2O2
stoichiometric coefficient: 1.0

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__phenylethylamine-_H2O-_O2-RIGHT__NH3-_H2O2-_phenylacetaldehyde-_r1
controller: Phenylethylamine oxidase

PARTICIPANT STOICHIOMETRY r1 51
type: Stoichiometry
physical entity: NH3
stoichiometric coefficient: 1.0

NH3
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r1 53
type: Stoichiometry
physical entity: phenylacetaldehyde
stoichiometric coefficient: 1.0

Retina-specific copper amine oxidase
type: ProteinReference
xref: uniprot O75106 24
organism: Homo sapiens

Amine oxidase
type: ProteinReference
xref: uniprot Q6WIZ7 34
organism: Mus musculus

ISS
type: EvidenceCodeVocabulary
xref: eco ECO:0000250 4

Amine oxidase
type: ProteinReference
xref: uniprot Q6IMK7 33
organism: Mus musculus

uniprot Q812C9 35
type: UnificationXref
id: Q812C9
db: uniprot

uniprot H2R9Q9 17
type: UnificationXref
id: H2R9Q9
db: uniprot

ncbitaxon 9913 7
type: UnificationXref
id: 9913
db: ncbitaxon

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A452DHX8 6
organism: Bos taurus

ncbitaxon 9598 15
type: UnificationXref
id: 9598
db: ncbitaxon

Rattus norvegicus
type: BioSource
xref: ncbitaxon 10116 29

uniprot O46406 22
type: UnificationXref
id: O46406
db: uniprot

Amine oxidase
type: ProteinReference
xref: uniprot H2R2M5 16
organism: Pan troglodytes

Amine oxidase
type: ProteinReference
xref: uniprot F7GP69 13
organism: Macaca mulatta

uniprot Q6IMK7 33
type: UnificationXref
id: Q6IMK7
db: uniprot

uniprot Q9P7F2 40
type: UnificationXref
id: Q9P7F2
db: uniprot

Amine oxidase
type: ProteinReference
xref: uniprot F7GP66 12
organism: Macaca mulatta

ncbitaxon 284812 21
type: UnificationXref
id: 284812
db: ncbitaxon

Primary amine oxidase 1
type: ProteinReference
xref: uniprot O23349 18
organism: Arabidopsis thaliana

uniprot Q9STI3 41
type: UnificationXref
id: Q9STI3
db: uniprot

Amine oxidase
type: ProteinReference
xref: uniprot Q8L866 38
organism: Arabidopsis thaliana

uniprot Q8JZQ5 36
type: UnificationXref
id: Q8JZQ5
db: uniprot

Schizosaccharomyces pombe
type: BioSource
xref: ncbitaxon 284812 21

Amiloride-sensitive amine oxidase [copper-containing]
type: ProteinReference
xref: uniprot P36633 28
organism: Rattus norvegicus

uniprot O42890 20
type: UnificationXref
id: O42890
db: uniprot

uniprot P80668 2
type: UnificationXref
id: P80668
db: uniprot

Amine oxidase
type: ProteinReference
xref: uniprot Q9STI3 41
organism: Arabidopsis thaliana

Primary amine oxidase
type: ProteinReference
xref: uniprot P46883 31
organism: Escherichia coli

Amine oxidase
type: ProteinReference
xref: uniprot Q9STI4 42
organism: Arabidopsis thaliana

uniprot Q9M2B9 39
type: UnificationXref
id: Q9M2B9
db: uniprot

Pan troglodytes
type: BioSource
xref: ncbitaxon 9598 15

P03102
type: UnificationXref
id: P03102
db: PANTHER Pathway Component

ncbitaxon 9606 25
type: UnificationXref
id: 9606
db: ncbitaxon

P03103
type: UnificationXref
id: P03103
db: PANTHER Pathway Component

ncbitaxon 83333 3
type: UnificationXref
id: 83333
db: ncbitaxon

STATE_TRANSITION
type: RelationshipTypeVocabulary

STATE_TRANSITION
type: InteractionVocabulary

Amine oxidase
type: ProteinReference
xref: uniprot F6TU25 10
organism: Macaca mulatta

uniprot O70423 23
type: UnificationXref
id: O70423
db: uniprot

Primary amine oxidase 2
type: ProteinReference
xref: uniprot P0DO00 26
organism: Arabidopsis thaliana

uniprot F7GP66 12
type: UnificationXref
id: F7GP66
db: uniprot

phenylethylamine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

phenylacetate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

STATE_TRANSITION_LEFT__NAD-_H2O-_phenylacetaldehyde-RIGHT__phenylacetate-_NADH-_r2
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 44
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 45
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 43
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 47
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 46
left: H2O
left: NAD
left: phenylacetaldehyde
interaction type: STATE_TRANSITION
right: phenylacetate
right: NADH

Amiloride-sensitive amine oxidase [copper-containing]
type: ProteinReference
xref: uniprot Q8JZQ5 36
organism: Mus musculus

PARTICIPANT STOICHIOMETRY r2 44
type: Stoichiometry
physical entity: H2O
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r2 43
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r2 46
type: Stoichiometry
physical entity: phenylacetate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r2 45
type: Stoichiometry
physical entity: phenylacetaldehyde
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r2 47
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

uniprot F6TU25 10
type: UnificationXref
id: F6TU25
db: uniprot

Membrane primary amine oxidase
type: ProteinReference
xref: uniprot O70423 23
organism: Mus musculus

uniprot A0A452DHX8 6
type: UnificationXref
id: A0A452DHX8
db: uniprot

uniprot Q9STI4 42
type: UnificationXref
id: Q9STI4
db: uniprot

uniprot H2QD42 14
type: UnificationXref
id: H2QD42
db: uniprot

Copper amine oxidase-like protein cao2
type: ProteinReference
xref: uniprot O42890 20
organism: Schizosaccharomyces pombe

uniprot H2R2M5 16
type: UnificationXref
id: H2R2M5
db: uniprot

phenylacetaldehyde
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Amine oxidase
type: ProteinReference
xref: uniprot Q9M2B9 39
organism: Arabidopsis thaliana

Phenylethylamine oxidase
type: Protein
entity reference: Phenylethylamine oxidase
comment: SPECIES_TYPE=PROTEIN

Homo sapiens
type: BioSource
xref: ncbitaxon 9606 25

uniprot P0DO00 26
type: UnificationXref
id: P0DO00
db: uniprot

uniprot P19801 27
type: UnificationXref
id: P19801
db: uniprot

PANTHER Pathway P02766 1
type: UnificationXref
id: P02766
db: PANTHER Pathway

NAD
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Phenylethylamine oxidase
type: ProteinReference
xref: P03103
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Phenylethylamine degradation.PROTEIN.GENERIC.Phenylethylamine_br_oxidase
comment: ENTITY_REFERENCE_NOTES= Long Name: Phenylethylamine oxidase Synonym: Synonym not specified Accession: P03103
member entity reference: Amine oxidase
member entity reference: Uncharacterized protein
member entity reference: Primary amine oxidase, lung isozyme
member entity reference: Amiloride-sensitive amine oxidase [copper-containing]
member entity reference: Membrane primary amine oxidase
member entity reference: Copper amine oxidase 1
member entity reference: Retina-specific copper amine oxidase
member entity reference: Primary amine oxidase 1
member entity reference: Copper amine oxidase-like protein cao2
member entity reference: Glucose-6-phosphatase
member entity reference: Primary amine oxidase 2
member entity reference: Primary amine oxidase

PARTICIPANT STOICHIOMETRY r1 50
type: Stoichiometry
physical entity: O2
stoichiometric coefficient: 1.0

Arabidopsis thaliana
type: BioSource
xref: ncbitaxon 3702 19

Phenylethylamine degradation
type: Pathway
pathway component: STATE_TRANSITION_LEFT__NAD-_H2O-_phenylacetaldehyde-RIGHT__phenylacetate-_NADH-_r2
pathway component: STATE_TRANSITION_LEFT__phenylethylamine-_H2O-_O2-RIGHT__NH3-_H2O2-_phenylacetaldehyde-_r1
xref: PANTHER Pathway P02766 1
comment: MODEL_NOTES= Phenylethylamine degradation is the breakdown of phenylethylamine to phenylacetate and ultimately to succinyl-CoA for energy production. Website=www.biocyc.org/Ecoli/Pathways/ free text=Voet and Voet (textbook) Biochemistry

H2O
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Phenylacetaldehyde dehydrogenase
type: Protein
entity reference: Phenylacetaldehyde dehydrogenase
comment: SPECIES_TYPE=PROTEIN

Retina-specific copper amine oxidase
type: ProteinReference
xref: uniprot Q812C9 35
organism: Mus musculus

Primary amine oxidase, lung isozyme
type: ProteinReference
xref: uniprot O46406 22
organism: Bos taurus

uniprot E9Q745 8
type: UnificationXref
id: E9Q745
db: uniprot

PARTICIPANT STOICHIOMETRY r1 48
type: Stoichiometry
physical entity: phenylethylamine
stoichiometric coefficient: 1.0

Amine oxidase
type: ProteinReference
xref: uniprot H2R9Q9 17
organism: Pan troglodytes

Phenylacetaldehyde dehydrogenase
type: ProteinReference
xref: P03102
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Phenylethylamine degradation.PROTEIN.GENERIC.Phenylacetaldehyde_br_dehydrogenase
comment: ENTITY_REFERENCE_NOTES= Long Name: Phenylacetaldehyde dehydrogenase Synonym: Synonym not specified Accession: P03102
member entity reference: Phenylacetaldehyde dehydrogenase

PARTICIPANT STOICHIOMETRY r1 49
type: Stoichiometry
physical entity: H2O
stoichiometric coefficient: 1.0

uniprot O23349 18
type: UnificationXref
id: O23349
db: uniprot

uniprot Q8L866 38
type: UnificationXref
id: Q8L866
db: uniprot

STATE_TRANSITION_LEFT__phenylethylamine-_H2O-_O2-RIGHT__NH3-_H2O2-_phenylacetaldehyde-_r1
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 50
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 51
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 52
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 53
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 49
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 48
left: H2O
left: phenylethylamine
left: O2
interaction type: STATE_TRANSITION
right: H2O2
right: phenylacetaldehyde
right: NH3

Amiloride-sensitive amine oxidase [copper-containing]
type: ProteinReference
xref: uniprot P19801 27
organism: Homo sapiens

uniprot Q16853 32
type: UnificationXref
id: Q16853
db: uniprot

By Homology
type: RelationshipTypeVocabulary

uniprot Q8L742 37
type: UnificationXref
id: Q8L742
db: uniprot

Escherichia coli
type: BioSource
xref: ncbitaxon 83333 3

uniprot Q6WIZ7 34
type: UnificationXref
id: Q6WIZ7
db: uniprot

uniprot P43428 30
type: UnificationXref
id: P43428
db: uniprot

ncbitaxon 10116 29
type: UnificationXref
id: 10116
db: ncbitaxon

Amine oxidase
type: ProteinReference
xref: uniprot H2QD42 14
organism: Pan troglodytes

Glucose-6-phosphatase
type: ProteinReference
xref: uniprot P43428 30
organism: Rattus norvegicus

ncbitaxon 9544 11
type: UnificationXref
id: 9544
db: ncbitaxon