Non-specific serine/threonine protein kinase
Phosphatidylinositol 3-kinase catalytic subunit type 3
Mitogen activated protein kinase activated protein kinase
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.MAPKAP
ENTITY_REFERENCE_NOTES= Long Name: Mitogen activated protein kinase activated protein kinase Synonym: MK Accession: P04564
Mitogen-activated protein kinase kinase 3 and 6
ENTITY_REFERENCE_NOTES= Long Name: Mitogen activated protein kinase kinase 3/6 Synonym: MAPKK3/6,MKK3/6 Accession: P04568
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.MKK3/6
MODEL_NOTES=Panther Pathway: P04393 Cell proliferation is tightly regulated by exposure to serum, growth factors, survival factors and other cues from the cellular environment. The Ras signaling pathway plays an important role in transducing these extracellular cues, and stimulating cellular proliferation, differentiation and survival. Activating mutations in the Ras gene are frequently found in human cancers, leading to constitutive signaling throught the pathway and unregulated cell proliferation and survival. Medline=15519853 Medline=9685325 PMID: 15519853 PMID: 9685325
SOS Ras/Rac guanine nucleotide exchange factor 1
3-phosphoinositide dependent protein kinase 1
Dual specificity mitogen-activated protein kinase kinase 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Dual-specificity mitogen-activated protein kinase kinase 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit
Mitogen-activated protein kinase kinase 3
A-Raf proto-oncogene, serine/threonine kinase
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.Rho
ENTITY_REFERENCE_NOTES= Long Name: Rho Synonym: Synonym not specified Accession: P04578
Signal transducers and activators of transcription
ENTITY_REFERENCE_NOTES= Long Name: Signal transducer and activator of transcription Synonym: STAT Accession: P04566
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.Stat 1/3
Ral guanine nucleotide dissociation stimulator
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.AP1
ENTITY_REFERENCE_NOTES= Long Name: AP1 Synonym: Synonym not specified Accession: P04560
Cell division control protein 42 homolog isoform 2
T-lymphoma invasion and metastasis-inducing protein 1
T-cell lymphoma invasion and metastasis 1
Cyclic AMP-dependent transcription factor ATF-2
Mitogen-activated protein kinase kinase 6
Dual specificity mitogen-activated protein kinase kinase 3
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.GSK3
ENTITY_REFERENCE_NOTES= Long Name: Glycogen synthase kinase 3 Synonym: GSK3 Accession: P04546
T cell lymphoma invasion and metastasis 1
Ras-related C3 botulinum toxin substrate 1
V-ral simian leukemia viral oncogene homolog Ba (ras-related)
Mitogen activated protein kinase kinase 4/7
ENTITY_REFERENCE_NOTES= Long Name: Mitogen activated protein kinase kinase 4/7 Synonym: JNK kinase,JNKK,MKK4,MKK7,SEK1 Accession: P04565
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.MKK4/7
Website http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd
3-phosphoinositide-dependent protein kinase 1
SHC (Src homology 2 domain containing) transforming protein 1
B-Raf proto-oncogene, serine/threonine kinase
Mitogen-activated protein kinase kinase kinase 4
Raf-1 proto-oncogene, serine/threonine kinase
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.Tiam1
ENTITY_REFERENCE_NOTES= Long Name: T-cell lymphoma invasion and metastasis Synonym: T-cell lymphoma invasion and metastasis Accession: P04571
Dual specificity mitogen-activated protein kinase kinase 4
Mitogen-activated protein kinase kinase kinase 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Dual specificity mitogen-activated protein kinase kinase 7
Signal transducer and activator of transcription
-Ha-ras Harvey rat sarcoma viral oncogene homolog, like
Dual specificity mitogen-activated protein kinase kinase 2
ETS proto-oncogene 1, transcription factor
Mitogen-activated protein kinase kinase 7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
SOS Ras/Rho guanine nucleotide exchange factor 2
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Mitogen-activated protein kinase kinase 1
RAC-gamma serine/threonine-protein kinase
Mitogen-activated protein kinase-activated protein kinase 2
Signal transducer and activator of transcription 3
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.Sec5
ENTITY_REFERENCE_NOTES= Long Name: Sec5 Synonym: Synonym not specified Accession: P04545
Dual specificity mitogen-activated protein kinase kinase 6
Cell division control protein 42 homolog
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.MEK
ENTITY_REFERENCE_NOTES= Long Name: Mitogen activated protein kinase kinase Synonym: MAP kinase kinase,MAPKK,MEK Accession: P04557
V-ral simian leukemia viral oncogene homolog Ab (ras-related)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Ral guanine nucleotide dissociation stimulator,-like 1
RAC-alpha serine/threonine-protein kinase
Neuroblastoma RAS viral (v-ras) oncogene homolog
ENTITY_REFERENCE_NOTES= Long Name: Extracellular signal-regulated kinase Synonym: ERK,MAP kinase,MAPK,Mitogen activated protein kinase Accession: P04542
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.ERK
Ral guanine nucleotide dissociation stimulator-like 1
RAF proto-oncogene serine/threonine-protein kinase
ENTITY_REFERENCE_NOTES= Long Name: Ral guanine nucleotide dissociation stimulator Synonym: RalGDS Accession: P04551
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.RalGDS
3-phosphoinositide-dependent protein kinase
ENTITY_REFERENCE_NOTES= Long Name: Phosphoinositide dependent kinase Synonym: PDK Accession: P04555
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.PDK
ENTITY_REFERENCE_NOTES= Long Name: p90 ribosomal S6 kinase Synonym: MAPK-activated protein kinase-1,MAPKAP-KI,p90RSK Accession: P04541
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.p90RSK
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.Ras
ENTITY_REFERENCE_NOTES= Long Name: Ras Synonym: Synonym not specified Accession: P04547
ENTITY_REFERENCE_NOTES= Long Name: Phospholipase D Synonym: PLD Accession: P04574
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.PLD
Mitogen-activated protein kinase kinase 2
Mitogen activated protein kinase kinase kinase
ENTITY_REFERENCE_NOTES= Long Name: Mitogen activated protein kinase kinase kinase Synonym: MAPKKK,MEK kinase,MEKK1,MEKK4 Accession: P04543
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.MEKK1/4
Ral guanine nucleotide dissociation stimulator-like 2
Harvey rat sarcoma viral oncogene homolog
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.Grb2
ENTITY_REFERENCE_NOTES= Long Name: Growth factor receptor-bound protein-2 Synonym: Synonym not specified Accession: P04544
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.AKT
ENTITY_REFERENCE_NOTES= Long Name: AKT Synonym: PKB,Protein Kinase B Accession: P04570
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.PAK
ENTITY_REFERENCE_NOTES= Long Name: P21 activated kinase Synonym: PAK Accession: P04553
ENTITY_REFERENCE_NOTES= Long Name: Serum response factor Synonym: SRF Accession: P04561
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.SRF
Ras-related C3 botulinum toxin substrate
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.Rac
ENTITY_REFERENCE_NOTES= Long Name: Rac Synonym: Synonym not specified Accession: P04559
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.Ets
ENTITY_REFERENCE_NOTES= Long Name: Ets Synonym: Synonym not specified Accession: P04563
Ras-related C3 botulinum toxin substrate 2
Mitogen-activated protein kinase kinase 4A
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.Ral
ENTITY_REFERENCE_NOTES= Long Name: Ral Synonym: Synonym not specified Accession: P04550
Ras-related C3 botulinum toxin substrate 3
Signal transducer and activator of transcription 1-alpha/beta
Signal transducer and activator of transcription 1
V-ral simian leukemia viral oncogene homolog A (ras-related)
Mitogen-activated protein kinase kinase 4
V-ral simian leukemia viral oncogene homolog A (Ras related)
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.TAK
ENTITY_REFERENCE_NOTES= Long Name: TAK Synonym: Synonym not specified Accession: P04575
Glycogen synthase kinase-3 beta isoform 1
ENTITY_REFERENCE_NOTES= Long Name: Raf Synonym: A-Raf,B-Raf,C-RAF,MAPKKK,MEKK,Mitogen activated protein kinase kinase kinase Accession: P04556
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.Raf
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.SOS
ENTITY_REFERENCE_NOTES= Long Name: Son of sevenless Synonym: SOS Accession: P04552
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Cdc42hs complexed with A peptide derived from P-21 activated kinase
Kirsten rat sarcoma viral oncogene homolog
ENTITY_REFERENCE_NOTES= Long Name: Cdc42 Synonym: Synonym not specified Accession: P04569
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.Cdc42
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.JNK
ENTITY_REFERENCE_NOTES= Long Name: Jun kinase n-terminal kinase Synonym: JNK,SAPK,stress activated protein kinase Accession: P04572
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.ATF2
ENTITY_REFERENCE_NOTES= Long Name: Activating transcription factor 2 Synonym: Synonym not specified Accession: P04548
Complex (Growth Factor Receptor/Growth Factor)
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.Elk-1
ENTITY_REFERENCE_NOTES= Long Name: Elk-1 Synonym: Synonym not specified Accession: P04573
ENTITY_REFERENCE_NOTES= Long Name: p38 mitogen activated protein kinase Synonym: p38,p38MAPK Accession: P04558
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.p38
SH2 homology domain containing transforming protein
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.Shc
ENTITY_REFERENCE_NOTES= Long Name: Shc Synonym: Synonym not specified Accession: P04579
Mitogen-activated protein kinase-activated protein kinase 2a
Jun proto-oncogene, AP-1 transcription factor subunit
ENTITY_REFERENCE_ID_DESC=Ras Pathway.PROTEIN.GENERIC.PI3K
ENTITY_REFERENCE_NOTES= Long Name: Phosphoinositide-3 kinase Synonym: PI3 kinase,PI3K Accession: P04567