uniprot O08651 72
type: UnificationXref
id: O08651
db: uniprot

Phosphoserine phosphatase
type: ProteinReference
xref: uniprot Q5M819 57
organism: Rattus norvegicus

3-phosph-hydroxypyruvate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Halobacterium salinarum
type: BioSource
xref: ncbitaxon 64091 63

ncbitaxon 224308 17
type: UnificationXref
id: 224308
db: ncbitaxon

D-3-phosphoglycerate dehydrogenase
type: ProteinReference
xref: uniprot P0A9T0 78
organism: Escherichia coli

Phosphoserine aminotransferase
type: Protein
entity reference: Phosphoserine aminotransferase
comment: SPECIES_TYPE=PROTEIN

ncbitaxon 9606 40
type: UnificationXref
id: 9606
db: ncbitaxon

uniprot Q58989 55
type: UnificationXref
id: Q58989
db: uniprot

ncbitaxon 64091 63
type: UnificationXref
id: 64091
db: ncbitaxon

Phosphoglycerate dehydrogenase, putative
type: ProteinReference
xref: uniprot Q9WYG2 100
organism: Thermotoga maritima

uniprot E2RPN5 42
type: UnificationXref
id: E2RPN5
db: uniprot

Anopheles gambiae
type: BioSource
xref: ncbitaxon 7165 25

5,10-CH2-THF
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ncbitaxon 6238 9
type: UnificationXref
id: 6238
db: ncbitaxon

PANTHER Pathway P02776 1
type: UnificationXref
id: P02776
db: PANTHER Pathway

D-3-phosphoglycerate dehydrogenase 1
type: ProteinReference
xref: uniprot P40054 80
organism: Saccharomyces cerevisiae

eco ECO:0000250 4
type: UnificationXref
id: ECO:0000250
db: eco

D-3-phosphoglycerate dehydrogenase
type: ProteinReference
xref: uniprot P73821 82
organism: Synechocystis

uniprot P23721 12
type: UnificationXref
id: P23721
db: uniprot

Phosphoserine phosphatase
type: ProteinReference
xref: uniprot Q9HMR1 62
organism: Halobacterium salinarum

D-3-phosphoglycerate dehydrogenase
type: ProteinReference
xref: uniprot Q9HMR0 93
organism: Halobacterium salinarum

uniprot Q9HZ66 34
type: UnificationXref
id: Q9HZ66
db: uniprot

Phosphoserine phosphatase
type: Protein
entity reference: Phosphoserine phosphatase
comment: SPECIES_TYPE=PROTEIN

Phosphoserine phosphatase, chloroplastic
type: ProteinReference
xref: uniprot O82796 50
organism: Arabidopsis thaliana

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__H2O-_3_phospho_serine-RIGHT__PO4-_serine-_r3
controller: Phosphoserine phosphatase

Phosphoserine aminotransferase
type: ProteinReference
xref: PTHR43247:SF1
xref: uniprot A0A0G2K931 2
organism: Rattus norvegicus

Thermotoga maritima
type: BioSource
xref: ncbitaxon 243274 101

D-3-phosphoglycerate dehydrogenase 3, chloroplastic
type: ProteinReference
xref: uniprot Q9LT69 96
organism: Arabidopsis thaliana

H2O
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PO4
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Mus musculus
type: BioSource
xref: ncbitaxon 10090 31

Phosphoserine aminotransferase
type: ProteinReference
xref: uniprot P23721 12
xref: PTHR43247:SF1
organism: Escherichia coli

uniprot A8Y1C7 8
type: UnificationXref
id: A8Y1C7
db: uniprot

ncbitaxon 243274 101
type: UnificationXref
id: 243274
db: ncbitaxon

Probable phosphoserine aminotransferase
type: ProteinReference
xref: uniprot P91856 18
organism: Caenorhabditis elegans

Phosphoserine aminotransferase
type: ProteinReference
xref: uniprot Q5TRW7 24
organism: Anopheles gambiae

uniprot A0A061ACK7 41
type: UnificationXref
id: A0A061ACK7
db: uniprot

uniprot O53289 48
type: UnificationXref
id: O53289
db: uniprot

uniprot P78330 53
type: UnificationXref
id: P78330
db: uniprot

Saccharomyces cerevisiae
type: BioSource
xref: ncbitaxon 559292 15

Synechocystis
type: BioSource
xref: ncbitaxon 1111708 83

Drosophila melanogaster
type: BioSource
xref: ncbitaxon 7227 38

uniprot Q10349 22
type: UnificationXref
id: Q10349
db: uniprot

ncbitaxon 83332 21
type: UnificationXref
id: 83332
db: ncbitaxon

D-3-phosphoglycerate dehydrogenase
type: ProteinReference
xref: uniprot P35136 79
organism: Bacillus subtilis

ISS
type: EvidenceCodeVocabulary
xref: eco ECO:0000250 4

Phosphoserine aminotransferase
type: ProteinReference
xref: uniprot P33330 14
xref: PTHR43247:SF1
organism: Saccharomyces cerevisiae

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__glutamate-_3_phosph_hydroxypyruvate-RIGHT__3_phospho_serine-_ketoglutarate-_r2
controller: Phosphoserine aminotransferase

uniprot P80862 16
type: UnificationXref
id: P80862
db: uniprot

D-3-phosphoglycerate dehydrogenase
type: ProteinReference
xref: uniprot O67741 76
organism: Aquifex aeolicus

uniprot Q9S281 65
type: UnificationXref
id: Q9S281
db: uniprot

Phosphoserine aminotransferase
type: ProteinReference
xref: uniprot Q9F2Y1 32
organism: Streptomyces coelicolor

uniprot O17626 73
type: UnificationXref
id: O17626
db: uniprot

ncbitaxon 188937 60
type: UnificationXref
id: 188937
db: ncbitaxon

uniprot O74382 49
type: UnificationXref
id: O74382
db: uniprot

ncbitaxon 10116 3
type: UnificationXref
id: 10116
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r1 117
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

STATE_TRANSITION_LEFT__NAD-_3_phosphoglycerate-RIGHT__NADH-_3_phosph_hydroxypyruvate-_r1
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 119
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 118
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 120
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 117
left: NAD
left: 3-phosphoglycerate
interaction type: STATE_TRANSITION
right: 3-phosph-hydroxypyruvate
right: NADH

Phosphoserine phosphatase
type: ProteinReference
xref: uniprot P78330 53
organism: Homo sapiens

PARTICIPANT STOICHIOMETRY r1 118
type: Stoichiometry
physical entity: 3-phosphoglycerate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r1 119
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Monodelphis domestica
type: BioSource
xref: ncbitaxon 13616 45

STATE_TRANSITION_LEFT__H2O-_3_phospho_serine-RIGHT__PO4-_serine-_r3
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 112
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 110
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 109
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 111
left: 3-phospho-serine
left: H2O
interaction type: STATE_TRANSITION
right: PO4
right: serine

ncbitaxon 224324 77
type: UnificationXref
id: 224324
db: ncbitaxon

uniprot P91856 18
type: UnificationXref
id: P91856
db: uniprot

uniprot Q8LMR0 26
type: UnificationXref
id: Q8LMR0
db: uniprot

Schizosaccharomyces pombe
type: BioSource
xref: ncbitaxon 284812 23

Phosphoserine phosphatase
type: ProteinReference
xref: uniprot Q2KHU0 54
organism: Bos taurus

ncbitaxon 9544 11
type: UnificationXref
id: 9544
db: ncbitaxon

D-3-phosphoglycerate dehydrogenase
type: ProteinReference
xref: uniprot O08651 72
organism: Rattus norvegicus

Pan troglodytes
type: BioSource
xref: ncbitaxon 9598 47

D-isomer specific 2-hydroxyacid dehydrogenase family
type: ProteinReference
xref: uniprot P73990 84
organism: Synechocystis

PSPH isoform 1
type: ProteinReference
xref: uniprot H2QUL8 46
organism: Pan troglodytes

ncbitaxon 6239 19
type: UnificationXref
id: 6239
db: ncbitaxon

Probable phosphoserine phosphatase
type: ProteinReference
xref: uniprot Q9HUK5 64
organism: Pseudomonas aeruginosa

uniprot A0A3S5ZPF7 6
type: UnificationXref
id: A0A3S5ZPF7
db: uniprot

Phosphoserine aminotransferase
type: ProteinReference
xref: uniprot P9WQ73 20
organism: Mycobacterium tuberculosis

Putative phosphoserine aminotransferase
type: ProteinReference
xref: uniprot Q10349 22
organism: Schizosaccharomyces pombe

PARTICIPANT STOICHIOMETRY r1 120
type: Stoichiometry
physical entity: 3-phosph-hydroxypyruvate
stoichiometric coefficient: 1.0

Phosphoserine aminotransferase
type: ProteinReference
xref: P03157
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: Phosphoserine aminotransferase Synonym: Synonym not specified Accession: P03157
comment: ENTITY_REFERENCE_ID_DESC=Serine glycine biosynthesis.PROTEIN.GENERIC.Phosphoserine_br_aminotransferase
member entity reference: Phosphoserine aminotransferase
member entity reference: Probable phosphoserine aminotransferase
member entity reference: Putative phosphoserine aminotransferase
member entity reference: Phosphoserine aminotransferase 2, chloroplastic
member entity reference: Phosphoserine aminotransferase 1, chloroplastic

uniprot Q8THT3 59
type: UnificationXref
id: Q8THT3
db: uniprot

PTHR43247:SF5
type: RelationshipXref
id: PTHR43247:SF5
db: PANTHER Family
relationship type: By Homology

ncbitaxon 83333 13
type: UnificationXref
id: 83333
db: ncbitaxon

PTHR43247:SF3
type: RelationshipXref
id: PTHR43247:SF3
db: PANTHER Family
relationship type: By Homology

PTHR43247:SF1
type: RelationshipXref
id: PTHR43247:SF1
db: PANTHER Family
relationship type: By Homology

uniprot Q7Q038 58
type: UnificationXref
id: Q7Q038
db: uniprot

uniprot Q9X1C1 102
type: UnificationXref
id: Q9X1C1
db: uniprot

ketoglutarate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot F7DRL6 69
type: UnificationXref
id: F7DRL6
db: uniprot

ncbitaxon 100226 33
type: UnificationXref
id: 100226
db: ncbitaxon

Hydroxypyruvate reductase
type: ProteinReference
xref: uniprot Q9X1C1 102
organism: Thermotoga maritima

Deinococcus radiodurans
type: BioSource
xref: ncbitaxon 243230 98

uniprot O04130 71
type: UnificationXref
id: O04130
db: uniprot

Homo sapiens
type: BioSource
xref: ncbitaxon 9606 40

ncbitaxon 3702 29
type: UnificationXref
id: 3702
db: ncbitaxon

uniprot Q8TT47 90
type: UnificationXref
id: Q8TT47
db: uniprot

Methanocaldococcus jannaschii
type: BioSource
xref: ncbitaxon 243232 56

Phosphoglycerate dehydrogenase
type: ProteinReference
xref: P03160
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: Phosphoglycerate dehydrogenase Synonym: Synonym not specified Accession: P03160
comment: ENTITY_REFERENCE_ID_DESC=Serine glycine biosynthesis.PROTEIN.GENERIC.Phosphoglycerate_br_dehydrogenase
member entity reference: D-3-phosphoglycerate dehydrogenase
member entity reference: Phosphoglycerate dehydrogenase
member entity reference: D-3-phosphoglycerate dehydrogenase (SerA)
member entity reference: Putative D-3-phosphoglycerate dehydrogenase
member entity reference: D-isomer specific 2-hydroxyacid dehydrogenase family
member entity reference: D-3-phosphoglycerate dehydrogenase 2
member entity reference: D-3-phosphoglycerate dehydrogenase 3, chloroplastic
member entity reference: AGAP008849-PA
member entity reference: D-3-phosphoglycerate dehydrogenase 1
member entity reference: GH03305p
member entity reference: D-3-phosphoglycerate dehydrogenase 2, chloroplastic
member entity reference: D-3-phosphoglycerate dehydrogenase 1, chloroplastic
member entity reference: Uncharacterized protein
member entity reference: Phosphoglycerate dehydrogenase, putative
member entity reference: Hydroxypyruvate reductase
member entity reference: Protein CBG20736

uniprot Q9WYG2 100
type: UnificationXref
id: Q9WYG2
db: uniprot

Phosphoserine phosphatase
type: ProteinReference
xref: uniprot P42941 52
organism: Saccharomyces cerevisiae

NADH
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Arabidopsis thaliana
type: BioSource
xref: ncbitaxon 3702 29

uniprot Q99LS3 61
type: UnificationXref
id: Q99LS3
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F7B7E7 44
organism: Monodelphis domestica

D-3-phosphoglycerate dehydrogenase
type: ProteinReference
xref: uniprot K7DD09 70
organism: Pan troglodytes

D-3-phosphoglycerate dehydrogenase 1, chloroplastic
type: ProteinReference
xref: uniprot O49485 75
organism: Arabidopsis thaliana

uniprot Q9VKI8 99
type: UnificationXref
id: Q9VKI8
db: uniprot

Mycobacterium tuberculosis
type: BioSource
xref: ncbitaxon 83332 21

ncbitaxon 13616 45
type: UnificationXref
id: 13616
db: ncbitaxon

uniprot F7B7E7 44
type: UnificationXref
id: F7B7E7
db: uniprot

Escherichia coli
type: BioSource
xref: ncbitaxon 83333 13

Glycine hydroxymethyltransferase
type: Protein
comment: SPECIES_TYPE=PROTEIN

uniprot Q9HMR1 62
type: UnificationXref
id: Q9HMR1
db: uniprot

Probable phosphoserine aminotransferase
type: ProteinReference
xref: uniprot Q9VAN0 37
organism: Drosophila melanogaster

uniprot Q5M819 57
type: UnificationXref
id: Q5M819
db: uniprot

glycine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q2KHU0 54
type: UnificationXref
id: Q2KHU0
db: uniprot

Phosphoserine phosphatase
type: ProteinReference
xref: uniprot Q9S281 65
organism: Streptomyces coelicolor

Phosphoserine aminotransferase
type: ProteinReference
xref: uniprot Q9Y617 39
xref: PTHR43247:SF5
organism: Homo sapiens

NAD
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q9HSS1 94
type: UnificationXref
id: Q9HSS1
db: uniprot

uniprot A8XYH5 68
type: UnificationXref
id: A8XYH5
db: uniprot

D-3-phosphoglycerate dehydrogenase
type: ProteinReference
xref: uniprot Q9I6H5 95
organism: Pseudomonas aeruginosa

Putative D-3-phosphoglycerate dehydrogenase
type: ProteinReference
xref: uniprot P87228 85
organism: Schizosaccharomyces pombe

ncbitaxon 10090 31
type: UnificationXref
id: 10090
db: ncbitaxon

STATE_TRANSITION_LEFT__serine-_THF-RIGHT__H2O-_5,10_CH2_THF-_glycine-_re5
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY re5 108
participant stoichiometry: PARTICIPANT STOICHIOMETRY re5 104
participant stoichiometry: PARTICIPANT STOICHIOMETRY re5 106
participant stoichiometry: PARTICIPANT STOICHIOMETRY re5 105
participant stoichiometry: PARTICIPANT STOICHIOMETRY re5 107
left: THF
left: serine
interaction type: STATE_TRANSITION
right: 5,10-CH2-THF
right: H2O
right: glycine

THF
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q9Z564 103
type: UnificationXref
id: Q9Z564
db: uniprot

Phosphoserine aminotransferase
type: ProteinReference
xref: uniprot P80862 16
xref: PTHR43247:SF1
organism: Bacillus subtilis

Phosphoserine phosphatase
type: ProteinReference
xref: P03159
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: Phosphoserine phosphatase Synonym: Synonym not specified Accession: P03159
comment: ENTITY_REFERENCE_ID_DESC=Serine glycine biosynthesis.PROTEIN.GENERIC.Phosphoserine_br_phosphatase
member entity reference: Phosphoserine phosphatase
member entity reference: Uncharacterized protein
member entity reference: Probable phosphoserine phosphatase
member entity reference: PSPH isoform 1
member entity reference: AGAP012247-PA (Fragment)
member entity reference: Phosphoserine phosphatase, chloroplastic
member entity reference: Phosphoserine phosphatase SerB2

serine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

D-3-phosphoglycerate dehydrogenase
type: ProteinReference
xref: uniprot F7DRL6 69
organism: Macaca mulatta

ncbitaxon 559292 15
type: UnificationXref
id: 559292
db: ncbitaxon

uniprot O49485 75
type: UnificationXref
id: O49485
db: uniprot

ncbitaxon 9913 7
type: UnificationXref
id: 9913
db: ncbitaxon

Phosphoserine aminotransferase
type: ProteinReference
xref: uniprot A0A3S5ZPF7 6
xref: PTHR43247:SF1
organism: Bos taurus

uniprot O67741 76
type: UnificationXref
id: O67741
db: uniprot

D-3-phosphoglycerate dehydrogenase
type: ProteinReference
xref: uniprot Q9Z564 103
organism: Streptomyces coelicolor

Serine glycine biosynthesis
type: Pathway
pathway component: STATE_TRANSITION_LEFT__H2O-_3_phospho_serine-RIGHT__PO4-_serine-_r3
pathway component: STATE_TRANSITION_LEFT__serine-_THF-RIGHT__H2O-_5,10_CH2_THF-_glycine-_re5
pathway component: STATE_TRANSITION_LEFT__NAD-_3_phosphoglycerate-RIGHT__NADH-_3_phosph_hydroxypyruvate-_r1
pathway component: STATE_TRANSITION_LEFT__glutamate-_3_phosph_hydroxypyruvate-RIGHT__3_phospho_serine-_ketoglutarate-_r2
xref: PANTHER Pathway P02776 1
comment: MODEL_NOTES= The biosynthesis of amino acids serine and glycine both critical for protein synthesis. Website=www.biocyc.org/Ecoli/Pathways/ free text=Biochemistry (text) Voet and Voet

STATE_TRANSITION_LEFT__glutamate-_3_phosph_hydroxypyruvate-RIGHT__3_phospho_serine-_ketoglutarate-_r2
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 116
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 114
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 113
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 115
left: 3-phosph-hydroxypyruvate
left: glutamate
interaction type: STATE_TRANSITION
right: 3-phospho-serine
right: ketoglutarate

uniprot P33330 14
type: UnificationXref
id: P33330
db: uniprot

uniprot P9WQ73 20
type: UnificationXref
id: P9WQ73
db: uniprot

uniprot P0AGB0 51
type: UnificationXref
id: P0AGB0
db: uniprot

uniprot P35136 79
type: UnificationXref
id: P35136
db: uniprot

Bacillus subtilis
type: BioSource
xref: ncbitaxon 224308 17

Bos taurus
type: BioSource
xref: ncbitaxon 9913 7

Macaca mulatta
type: BioSource
xref: ncbitaxon 9544 11

AGAP008849-PA
type: ProteinReference
xref: uniprot Q7PWU4 89
organism: Anopheles gambiae

D-3-phosphoglycerate dehydrogenase (SerA)
type: ProteinReference
xref: uniprot Q8ZTC7 91
organism: Pyrobaculum aerophilum

uniprot Q9HMR0 93
type: UnificationXref
id: Q9HMR0
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A061ACK7 41
organism: Caenorhabditis elegans

D-3-phosphoglycerate dehydrogenase
type: ProteinReference
xref: uniprot Q61753 88
organism: Mus musculus

Phosphoserine phosphatase
type: ProteinReference
xref: uniprot E2RPN5 42
organism: Canis lupus familiaris

P03157
type: UnificationXref
id: P03157
db: PANTHER Pathway Component

uniprot O43175 74
type: UnificationXref
id: O43175
db: uniprot

P03159
type: UnificationXref
id: P03159
db: PANTHER Pathway Component

ncbitaxon 9615 43
type: UnificationXref
id: 9615
db: ncbitaxon

Protein CBG20736
type: ProteinReference
xref: uniprot A8XYH5 68
organism: Caenorhabditis briggsae

uniprot Q9F2Y1 32
type: UnificationXref
id: Q9F2Y1
db: uniprot

ncbitaxon 7165 25
type: UnificationXref
id: 7165
db: ncbitaxon

Methanosarcina acetivorans
type: BioSource
xref: ncbitaxon 188937 60

uniprot P73990 84
type: UnificationXref
id: P73990
db: uniprot

P03160
type: UnificationXref
id: P03160
db: PANTHER Pathway Component

ncbitaxon 243230 98
type: UnificationXref
id: 243230
db: ncbitaxon

uniprot Q9I6H5 95
type: UnificationXref
id: Q9I6H5
db: uniprot

Phosphoglycerate dehydrogenase
type: ProteinReference
xref: uniprot Q9HSS1 94
organism: Halobacterium salinarum

Rattus norvegicus
type: BioSource
xref: ncbitaxon 10116 3

Aquifex aeolicus
type: BioSource
xref: ncbitaxon 224324 77

Probable phosphoserine phosphatase
type: ProteinReference
xref: uniprot O74382 49
organism: Schizosaccharomyces pombe

uniprot Q9RUU0 97
type: UnificationXref
id: Q9RUU0
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot O17626 73
organism: Caenorhabditis elegans

uniprot Q9LT69 96
type: UnificationXref
id: Q9LT69
db: uniprot

Canis lupus familiaris
type: BioSource
xref: ncbitaxon 9615 43

3-phosphoglycerate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

D-3-phosphoglycerate dehydrogenase
type: ProteinReference
xref: uniprot O43175 74
organism: Homo sapiens

ncbitaxon 7227 38
type: UnificationXref
id: 7227
db: ncbitaxon

uniprot P0A9T0 78
type: UnificationXref
id: P0A9T0
db: uniprot

glutamate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Phosphoserine phosphatase
type: ProteinReference
xref: uniprot Q99LS3 61
organism: Mus musculus

AGAP012247-PA (Fragment)
type: ProteinReference
xref: uniprot Q7Q038 58
organism: Anopheles gambiae

Phosphoserine phosphatase
type: ProteinReference
xref: uniprot Q8THT3 59
organism: Methanosarcina acetivorans

D-3-phosphoglycerate dehydrogenase
type: ProteinReference
xref: uniprot Q58424 87
organism: Methanocaldococcus jannaschii

PARTICIPANT STOICHIOMETRY r2 116
type: Stoichiometry
physical entity: ketoglutarate
stoichiometric coefficient: 1.0

GH03305p
type: ProteinReference
xref: uniprot Q9VKI8 99
organism: Drosophila melanogaster

D-3-phosphoglycerate dehydrogenase
type: ProteinReference
xref: uniprot P9WNX3 86
organism: Mycobacterium tuberculosis

PARTICIPANT STOICHIOMETRY r2 113
type: Stoichiometry
physical entity: glutamate
stoichiometric coefficient: 1.0

ncbitaxon 1111708 83
type: UnificationXref
id: 1111708
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r2 115
type: Stoichiometry
physical entity: 3-phospho-serine
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r2 114
type: Stoichiometry
physical entity: 3-phosph-hydroxypyruvate
stoichiometric coefficient: 1.0

Phosphoserine phosphatase
type: ProteinReference
xref: uniprot Q58989 55
organism: Methanocaldococcus jannaschii

Phosphoserine aminotransferase
type: ProteinReference
xref: uniprot Q9HZ66 34
organism: Pseudomonas aeruginosa

uniprot Q9VAN0 37
type: UnificationXref
id: Q9VAN0
db: uniprot

Pyrobaculum aerophilum
type: BioSource
xref: ncbitaxon 178306 92

uniprot P40054 80
type: UnificationXref
id: P40054
db: uniprot

uniprot Q58424 87
type: UnificationXref
id: Q58424
db: uniprot

uniprot P73821 82
type: UnificationXref
id: P73821
db: uniprot

Phosphoserine aminotransferase 1, chloroplastic
type: ProteinReference
xref: uniprot Q96255 28
xref: PTHR43247:SF3
organism: Arabidopsis thaliana

uniprot P40510 81
type: UnificationXref
id: P40510
db: uniprot

Phosphoserine aminotransferase
type: ProteinReference
xref: uniprot F7H2J8 10
xref: PTHR43247:SF1
organism: Macaca mulatta

By Homology
type: RelationshipTypeVocabulary

Phosphoserine phosphatase
type: ProteinReference
xref: uniprot Q9VSY6 66
organism: Drosophila melanogaster

Streptomyces coelicolor
type: BioSource
xref: ncbitaxon 100226 33

uniprot Q96255 28
type: UnificationXref
id: Q96255
db: uniprot

uniprot F7H2J8 10
type: UnificationXref
id: F7H2J8
db: uniprot

ncbitaxon 208964 35
type: UnificationXref
id: 208964
db: ncbitaxon

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__NAD-_3_phosphoglycerate-RIGHT__NADH-_3_phosph_hydroxypyruvate-_r1
controller: Phosphoglycerate dehydrogenase

uniprot Q9Y617 39
type: UnificationXref
id: Q9Y617
db: uniprot

uniprot Q9HUK5 64
type: UnificationXref
id: Q9HUK5
db: uniprot

uniprot Q5TRW7 24
type: UnificationXref
id: Q5TRW7
db: uniprot

STATE_TRANSITION
type: RelationshipTypeVocabulary

STATE_TRANSITION
type: InteractionVocabulary

D-3-phosphoglycerate dehydrogenase 2, chloroplastic
type: ProteinReference
xref: uniprot O04130 71
organism: Arabidopsis thaliana

D-3-phosphoglycerate dehydrogenase
type: ProteinReference
xref: uniprot A0A140T866 67
organism: Bos taurus

D-3-phosphoglycerate dehydrogenase
type: ProteinReference
xref: uniprot Q9RUU0 97
organism: Deinococcus radiodurans

uniprot H2QUL8 46
type: UnificationXref
id: H2QUL8
db: uniprot

D-3-phosphoglycerate dehydrogenase
type: ProteinReference
xref: uniprot Q8TT47 90
organism: Methanosarcina acetivorans

uniprot Q9SHP0 36
type: UnificationXref
id: Q9SHP0
db: uniprot

uniprot K7DD09 70
type: UnificationXref
id: K7DD09
db: uniprot

Phosphoserine phosphatase SerB2
type: ProteinReference
xref: uniprot O53289 48
organism: Mycobacterium tuberculosis

uniprot P87228 85
type: UnificationXref
id: P87228
db: uniprot

uniprot Q8ZTC7 91
type: UnificationXref
id: Q8ZTC7
db: uniprot

PARTICIPANT STOICHIOMETRY re5 105
type: Stoichiometry
physical entity: THF
stoichiometric coefficient: 1.0

uniprot O82796 50
type: UnificationXref
id: O82796
db: uniprot

PARTICIPANT STOICHIOMETRY re5 106
type: Stoichiometry
physical entity: H2O
stoichiometric coefficient: 1.0

Phosphoserine aminotransferase
type: ProteinReference
xref: uniprot A8Y1C7 8
organism: Caenorhabditis briggsae

uniprot P9WNX3 86
type: UnificationXref
id: P9WNX3
db: uniprot

PARTICIPANT STOICHIOMETRY re5 107
type: Stoichiometry
physical entity: 5,10-CH2-THF
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY re5 108
type: Stoichiometry
physical entity: glycine
stoichiometric coefficient: 1.0

uniprot A0A0G2K931 2
type: UnificationXref
id: A0A0G2K931
db: uniprot

uniprot Q7PWU4 89
type: UnificationXref
id: Q7PWU4
db: uniprot

Phosphoserine aminotransferase 2, chloroplastic
type: ProteinReference
xref: uniprot Q9SHP0 36
organism: Arabidopsis thaliana

Phosphoserine aminotransferase
type: ProteinReference
xref: uniprot Q8LMR0 26
organism: Oryza sativa

PARTICIPANT STOICHIOMETRY re5 104
type: Stoichiometry
physical entity: serine
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r3 110
type: Stoichiometry
physical entity: 3-phospho-serine
stoichiometric coefficient: 1.0

Phosphoserine aminotransferase
type: ProteinReference
xref: uniprot Q99K85 30
xref: PTHR43247:SF1
organism: Mus musculus

ncbitaxon 284812 23
type: UnificationXref
id: 284812
db: ncbitaxon

Caenorhabditis briggsae
type: BioSource
xref: ncbitaxon 6238 9

Caenorhabditis elegans
type: BioSource
xref: ncbitaxon 6239 19

ncbitaxon 243232 56
type: UnificationXref
id: 243232
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r3 112
type: Stoichiometry
physical entity: serine
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r3 111
type: Stoichiometry
physical entity: PO4
stoichiometric coefficient: 1.0

uniprot P42941 52
type: UnificationXref
id: P42941
db: uniprot

uniprot A0A140T866 67
type: UnificationXref
id: A0A140T866
db: uniprot

uniprot Q9VSY6 66
type: UnificationXref
id: Q9VSY6
db: uniprot

ncbitaxon 178306 92
type: UnificationXref
id: 178306
db: ncbitaxon

D-3-phosphoglycerate dehydrogenase 2
type: ProteinReference
xref: uniprot P40510 81
organism: Saccharomyces cerevisiae

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__serine-_THF-RIGHT__H2O-_5,10_CH2_THF-_glycine-_re5
controller: Glycine hydroxymethyltransferase

ncbitaxon 9598 47
type: UnificationXref
id: 9598
db: ncbitaxon

Phosphoserine phosphatase
type: ProteinReference
xref: uniprot P0AGB0 51
organism: Escherichia coli

uniprot Q99K85 30
type: UnificationXref
id: Q99K85
db: uniprot

Oryza sativa
type: BioSource
xref: ncbitaxon 39947 27

Pseudomonas aeruginosa
type: BioSource
xref: ncbitaxon 208964 35

ncbitaxon 39947 27
type: UnificationXref
id: 39947
db: ncbitaxon

uniprot Q61753 88
type: UnificationXref
id: Q61753
db: uniprot

PARTICIPANT STOICHIOMETRY r3 109
type: Stoichiometry
physical entity: H2O
stoichiometric coefficient: 1.0

Phosphoglycerate dehydrogenase
type: Protein
entity reference: Phosphoglycerate dehydrogenase
comment: SPECIES_TYPE=PROTEIN

3-phospho-serine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE