uniprot P39692 6
type: UnificationXref
id: P39692
db: uniprot

Sulfite reductase [NADPH] flavoprotein alpha-component
type: ProteinReference
xref: uniprot O32214 2
organism: Bacillus subtilis

Sulfite reductase
type: Protein
entity reference: Sulfite reductase
comment: SPECIES_TYPE=PROTEIN

3 NADP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

NADPH oxidoreductase A
type: ProteinReference
xref: uniprot Q54B10 8
organism: Dictyostelium discoideum

ncbitaxon 559292 7
type: UnificationXref
id: 559292
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r3 10
type: Stoichiometry
physical entity: RSH
stoichiometric coefficient: 1.0

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__3__NADPH-_SO3-RIGHT__3_NADP-_SH2-_r4
controller: Sulfite reductase

Sulfate assimilation
type: Pathway
pathway component: STATE_TRANSITION_LEFT__RSH-_PAPS-RIGHT__RSSR-_SO3-_r3
pathway component: STATE_TRANSITION_LEFT__3__NADPH-_SO3-RIGHT__3_NADP-_SH2-_r4
pathway component: STATE_TRANSITION_LEFT__ATP-_SO4-RIGHT__APS-_PPi-_r1
pathway component: STATE_TRANSITION_LEFT__APS-_ATP-RIGHT__ADP-_PAPS-_r2
xref: PANTHER Pathway P02778 1
comment: MODEL_NOTES= Sulfur assimilation is the enzymatic conversion of sulfate to hydrogen sulfide. Sulfur in sulfate can't be utilized directly by prokaryotes and must be converted to hydrogen sulfide for sulfur utilization. Website=www.biocyc.org/Ecoli/Pathways/ free text=Voet and Voet (textbook) Biochemistry

PPi
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r3 11
type: Stoichiometry
physical entity: PAPS
stoichiometric coefficient: 1.0

RSH
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r3 12
type: Stoichiometry
physical entity: RSSR
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r3 13
type: Stoichiometry
physical entity: SO3
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r1 20
type: Stoichiometry
physical entity: APS
stoichiometric coefficient: 1.0

Sulfate adenylyltransferase
type: Protein
comment: SPECIES_TYPE=PROTEIN

STATE_TRANSITION
type: InteractionVocabulary

STATE_TRANSITION
type: RelationshipTypeVocabulary

PARTICIPANT STOICHIOMETRY r1 21
type: Stoichiometry
physical entity: PPi
stoichiometric coefficient: 1.0

Bacillus subtilis
type: BioSource
xref: ncbitaxon 224308 3

STATE_TRANSITION_LEFT__3__NADPH-_SO3-RIGHT__3_NADP-_SH2-_r4
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 24
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 25
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 22
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 23
left: SO3
left: 3 NADPH
interaction type: STATE_TRANSITION
right: SH2
right: 3 NADP

PANTHER Pathway P02778 1
type: UnificationXref
id: P02778
db: PANTHER Pathway

uniprot O32214 2
type: UnificationXref
id: O32214
db: uniprot

ADP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Dictyostelium discoideum
type: BioSource
xref: ncbitaxon 44689 9

PARTICIPANT STOICHIOMETRY r4 24
type: Stoichiometry
physical entity: 3 NADP
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r4 25
type: Stoichiometry
physical entity: SH2
stoichiometric coefficient: 1.0

uniprot P38038 4
type: UnificationXref
id: P38038
db: uniprot

SO4
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r4 22
type: Stoichiometry
physical entity: 3 NADPH
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r4 23
type: Stoichiometry
physical entity: SO3
stoichiometric coefficient: 1.0

Sulfite reductase [NADPH] flavoprotein alpha-component
type: ProteinReference
xref: uniprot P38038 4
organism: Escherichia coli

PARTICIPANT STOICHIOMETRY r2 14
type: Stoichiometry
physical entity: APS
stoichiometric coefficient: 1.0

Adenylylsulfate kinase
type: Protein
comment: SPECIES_TYPE=PROTEIN

STATE_TRANSITION_LEFT__RSH-_PAPS-RIGHT__RSSR-_SO3-_r3
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 13
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 12
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 11
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 10
left: RSH
left: PAPS
interaction type: STATE_TRANSITION
right: SO3
right: RSSR

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__ATP-_SO4-RIGHT__APS-_PPi-_r1
controller: Sulfate adenylyltransferase

PARTICIPANT STOICHIOMETRY r2 17
type: Stoichiometry
physical entity: PAPS
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r2 16
type: Stoichiometry
physical entity: ADP
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r2 15
type: Stoichiometry
physical entity: ATP
stoichiometric coefficient: 1.0

SO3
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Saccharomyces cerevisiae
type: BioSource
xref: ncbitaxon 559292 7

STATE_TRANSITION_LEFT__ATP-_SO4-RIGHT__APS-_PPi-_r1
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 20
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 19
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 21
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 18
left: SO4
left: ATP
interaction type: STATE_TRANSITION
right: APS
right: PPi

RSSR
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

3 NADPH
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

APS
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

3-Phospho-adenylylsulfate reductase
type: Protein
comment: SPECIES_TYPE=PROTEIN

PAPS
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ncbitaxon 44689 9
type: UnificationXref
id: 44689
db: ncbitaxon

ncbitaxon 224308 3
type: UnificationXref
id: 224308
db: ncbitaxon

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__APS-_ATP-RIGHT__ADP-_PAPS-_r2
controller: Adenylylsulfate kinase

P03165
type: UnificationXref
id: P03165
db: PANTHER Pathway Component

Sulfite reductase [NADPH] flavoprotein component
type: ProteinReference
xref: uniprot P39692 6
organism: Saccharomyces cerevisiae

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__RSH-_PAPS-RIGHT__RSSR-_SO3-_r3
controller: 3-Phospho-adenylylsulfate reductase

Sulfite reductase
type: ProteinReference
xref: P03165
comment: ENTITY_REFERENCE_NOTES= Long Name: Sulfite reductase Synonym: Synonym not specified Accession: P03165
comment: ENTITY_REFERENCE_ID_DESC=Sulfate assimilation.PROTEIN.GENERIC.Sulfite reductase
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
member entity reference: NADPH oxidoreductase A
member entity reference: Sulfite reductase [NADPH] flavoprotein component
member entity reference: Sulfite reductase [NADPH] flavoprotein alpha-component

STATE_TRANSITION_LEFT__APS-_ATP-RIGHT__ADP-_PAPS-_r2
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 14
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 16
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 17
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 15
left: APS
left: ATP
interaction type: STATE_TRANSITION
right: ADP
right: PAPS

ncbitaxon 83333 5
type: UnificationXref
id: 83333
db: ncbitaxon

Escherichia coli
type: BioSource
xref: ncbitaxon 83333 5

PARTICIPANT STOICHIOMETRY r1 19
type: Stoichiometry
physical entity: SO4
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r1 18
type: Stoichiometry
physical entity: ATP
stoichiometric coefficient: 1.0

ATP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q54B10 8
type: UnificationXref
id: Q54B10
db: uniprot

SH2
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE