uniprot Q9BT88 83
type: UnificationXref
id: Q9BT88
db: uniprot

PTHR10480:SF8
type: RelationshipXref
id: PTHR10480:SF8
db: PANTHER Family
relationship type: By Homology

Ras-related protein Rab-3A
type: ProteinReference
xref: PTHR47980:SF9
xref: uniprot P63012 193
organism: Rattus norvegicus

Ras-related protein Rab-3A
type: ProteinReference
xref: PTHR47980:SF9
xref: uniprot P63011 192
organism: Mus musculus

uniprot F7H4N5 107
type: UnificationXref
id: F7H4N5
db: uniprot

uniprot P17600 154
type: UnificationXref
id: P17600
db: uniprot

ncbitaxon 6239 61
type: UnificationXref
id: 6239
db: ncbitaxon

Synaptophysin
type: ProteinReference
xref: PTHR10306:SF10
xref: uniprot F7DFQ7 169
organism: Xenopus tropicalis

Uncharacterized protein
type: ProteinReference
xref: uniprot F6TAG2 37
organism: Monodelphis domestica

Synaptobrevin
type: Protein
entity reference: Synaptobrevin
feature: COMPLEX PARTICIPANT BINDING FEATURE s22 sa14 198
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

ncbitaxon 7227 53
type: UnificationXref
id: 7227
db: ncbitaxon

uniprot A0A2I3TBU2 90
type: UnificationXref
id: A0A2I3TBU2
db: uniprot

uniprot A0A3Q1LZT1 124
type: UnificationXref
id: A0A3Q1LZT1
db: uniprot

uniprot Q9R0N5 85
type: UnificationXref
id: Q9R0N5
db: uniprot

GO GO:0008021 2
type: UnificationXref
id: GO:0008021
db: GO

PTHR10480:SF2
type: RelationshipXref
id: PTHR10480:SF2
db: PANTHER Family
relationship type: By Homology

uniprot A0A2I3RZD4 9
type: UnificationXref
id: A0A2I3RZD4
db: uniprot

SNAP-25
type: Protein
entity reference: SNAP-25
cellular location: axon terminus
comment: SPECIES_TYPE=PROTEIN

uniprot F6QFD5 35
type: UnificationXref
id: F6QFD5
db: uniprot

Vesicle-fusing ATPase 2
type: ProteinReference
xref: PTHR23078:SF3
xref: uniprot P54351 148
organism: Drosophila melanogaster

uniprot P08247 171
type: UnificationXref
id: P08247
db: uniprot

uniprot E1BGL9 26
type: UnificationXref
id: E1BGL9
db: uniprot

SNARE complex
type: Complex
cellular location: synaptic vesicle

Mus musculus
type: BioSource
xref: ncbitaxon 10090 50

uniprot P97610 72
type: UnificationXref
id: P97610
db: uniprot

Synaptotagmin
type: Protein
entity reference: Synaptotagmin
feature: COMPLEX PARTICIPANT BINDING FEATURE s21 sa13 196
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

uniprot G7MDX8 44
type: UnificationXref
id: G7MDX8
db: uniprot

Synapsin
type: ProteinReference
xref: PTHR10841:SF17
xref: uniprot Q24546 155
organism: Drosophila melanogaster

RIM1alpha/2alpha
type: ProteinReference
xref: P05776
standard name: Rab3A-interacting protein 1alpha/2alpha
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Rab3A-interacting protein 1alpha/2alpha Synonym: Synonym not specified Accession: P05776
comment: ENTITY_REFERENCE_ID_DESC=Synaptic_vesicle_trafficking.PROTEIN.GENERIC.RIM1_alpha__slash_2_alpha_
member entity reference: Regulating synaptic membrane exocytosis protein 1
member entity reference: Uncharacterized protein
member entity reference: Regulating synaptic membrane exocytosis protein 2
member entity reference: Regulating synaptic membrane exocytosis 1

Synaptotagmin-12
type: ProteinReference
xref: uniprot Q920N7 78
organism: Mus musculus

Saccharomyces cerevisiae
type: BioSource
xref: ncbitaxon 559292 144

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A1D5RJ25 6
organism: Macaca mulatta

uniprot P11023 190
type: UnificationXref
id: P11023
db: uniprot

Drosophila melanogaster
type: BioSource
xref: ncbitaxon 7227 53

PTHR19305:SF14
type: RelationshipXref
id: PTHR19305:SF14
db: PANTHER Family
relationship type: By Homology

uniprot F6UNB0 92
type: UnificationXref
id: F6UNB0
db: uniprot

N-ethylmaleimide sensitive factor, vesicle fusing ATPase
type: ProteinReference
xref: uniprot H2QD95 142
xref: PTHR23078:SF3
organism: Pan troglodytes

Synaptotagmin
type: Protein
entity reference: Synaptotagmin
feature: COMPLEX PARTICIPANT BINDING FEATURE s56 sa35 204
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

ncbitaxon 9913 19
type: UnificationXref
id: 9913
db: ncbitaxon

ncbitaxon 8364 39
type: UnificationXref
id: 8364
db: ncbitaxon

uniprot P46460 146
type: UnificationXref
id: P46460
db: uniprot

uniprot H2QUQ1 108
type: UnificationXref
id: H2QUQ1
db: uniprot

uniprot F6VGB3 168
type: UnificationXref
id: F6VGB3
db: uniprot

Protein unc-13 homolog C
type: ProteinReference
xref: PTHR10480:SF2
xref: uniprot Q8NB66 134
organism: Homo sapiens

UNC13D isoform 1
type: ProteinReference
xref: PTHR45999:SF3
xref: uniprot H2QDW4 129
organism: Pan troglodytes

uniprot P07825 170
type: UnificationXref
id: P07825
db: uniprot

Synapsin-1
type: ProteinReference
xref: uniprot P17600 154
xref: PTHR10841:SF24
organism: Homo sapiens

uniprot O35526 109
type: UnificationXref
id: O35526
db: uniprot

Synaptotagmin XII
type: ProteinReference
xref: uniprot F7GWY8 43
organism: Macaca mulatta

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A1D5QBF1 122
xref: PTHR45999:SF3
organism: Macaca mulatta

Syntaxin-binding protein 1
type: ProteinReference
xref: PTHR11679:SF35
xref: uniprot O08599 96
organism: Mus musculus

uniprot P60879 175
type: UnificationXref
id: P60879
db: uniprot

Synapsin-2
type: ProteinReference
xref: PTHR10841:SF20
xref: uniprot Q64332 157
organism: Mus musculus

uniprot F6PIV9 140
type: UnificationXref
id: F6PIV9
db: uniprot

uniprot O35681 49
type: UnificationXref
id: O35681
db: uniprot

Synaptotagmin-8
type: ProteinReference
xref: uniprot Q925B4 79
organism: Rattus norvegicus

Synaptosomal-associated protein 25
type: ProteinReference
xref: uniprot P60879 175
organism: Mus musculus

uniprot P21579 55
type: UnificationXref
id: P21579
db: uniprot

Synaptotagmin-8
type: ProteinReference
xref: uniprot Q9R0N6 86
organism: Mus musculus

Synaptotagmin-5
type: ProteinReference
xref: uniprot Q9R0N5 85
organism: Mus musculus

Synaptotagmin-11
type: ProteinReference
xref: uniprot Q9R0N3 84
organism: Mus musculus

Syntaxin 2
type: ProteinReference
xref: uniprot F1PR71 103
organism: Canis lupus familiaris

Synaptotagmin-6
type: ProteinReference
xref: uniprot Q9R0N8 88
organism: Mus musculus

Synaptosomal-associated protein 25
type: ProteinReference
xref: uniprot Q5R1X1 179
organism: Pan troglodytes

Synaptotagmin-7
type: ProteinReference
xref: uniprot Q9R0N7 87
organism: Mus musculus

Synaptosomal-associated protein 25
type: ProteinReference
xref: uniprot P60877 174
organism: Macaca mulatta

PTHR10306:SF10
type: RelationshipXref
id: PTHR10306:SF10
db: PANTHER Family
relationship type: By Homology

Syntaxin 1B
type: ProteinReference
xref: PTHR19957:SF334
xref: uniprot Q1MTI1 120
organism: Danio rerio

uniprot F1N548 166
type: UnificationXref
id: F1N548
db: uniprot

synaptic vesicle
type: CellularLocationVocabulary
xref: GO GO:0008021 2

uniprot F6XL12 94
type: UnificationXref
id: F6XL12
db: uniprot

DISSOCIATION_LEFT__synaptic_vesicle_fusion_complex-RIGHT__Synaptobrevin-_RIM1alpha_2alpha-_Syntaxin_1_2-_Munc13-_SNAP_25-_Rab3A-_Munc18-_Synaptotagmin-_re5
type: ComplexAssembly
spontaneous: false
conversion direction: LEFT_TO_RIGHT
xref: DISSOCIATION
participant stoichiometry: PARTICIPANT STOICHIOMETRY re5 229
participant stoichiometry: PARTICIPANT STOICHIOMETRY re5 226
participant stoichiometry: PARTICIPANT STOICHIOMETRY re5 223
participant stoichiometry: PARTICIPANT STOICHIOMETRY re5 227
participant stoichiometry: PARTICIPANT STOICHIOMETRY re5 225
participant stoichiometry: PARTICIPANT STOICHIOMETRY re5 221
participant stoichiometry: PARTICIPANT STOICHIOMETRY re5 228
participant stoichiometry: PARTICIPANT STOICHIOMETRY re5 224
participant stoichiometry: PARTICIPANT STOICHIOMETRY re5 222
left: synaptic vesicle fusion complex
interaction type: DISSOCIATION
right: Rab3A
right: Munc13
right: Munc18
right: Syntaxin 1/2
right: RIM1alpha/2alpha
right: Synaptobrevin
right: SNAP-25
right: Synaptotagmin

Munc13 s100 sa84 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Munc13
stoichiometric coefficient: 2.0

Synaptosomal-associated protein 25
type: ProteinReference
xref: uniprot P60880 176
organism: Homo sapiens

Pan troglodytes
type: BioSource
xref: ncbitaxon 9598 8

Synaptotagmin 12
type: ProteinReference
xref: uniprot E1BEH9 25
organism: Bos taurus

Xenopus tropicalis
type: BioSource
xref: ncbitaxon 8364 39

PTHR10024:SF227
type: RelationshipXref
id: PTHR10024:SF227
db: PANTHER Family
relationship type: By Homology

uniprot A0A2I3S3S5 101
type: UnificationXref
id: A0A2I3S3S5
db: uniprot

ncbitaxon 6238 23
type: UnificationXref
id: 6238
db: ncbitaxon

PTHR10024:SF223
type: RelationshipXref
id: PTHR10024:SF223
db: PANTHER Family
relationship type: By Homology

Regulating synaptic membrane exocytosis protein 1
type: ProteinReference
xref: PTHR12157:SF18
xref: uniprot Q86UR5 163
organism: Homo sapiens

uniprot A4IFJ2 21
type: UnificationXref
id: A4IFJ2
db: uniprot

TRIGGER
type: RelationshipTypeVocabulary

Synaptotagmin-12
type: ProteinReference
xref: uniprot P97610 72
organism: Rattus norvegicus

Synaptotagmin-12
type: ProteinReference
xref: uniprot Q8IV01 75
organism: Homo sapiens

ncbitaxon 7955 121
type: UnificationXref
id: 7955
db: ncbitaxon

Ras-related protein Rab-3A
type: ProteinReference
xref: uniprot P11023 190
organism: Bos taurus

uniprot Q9R0N7 87
type: UnificationXref
id: Q9R0N7
db: uniprot

uniprot A0A3Q1MKW3 20
type: UnificationXref
id: A0A3Q1MKW3
db: uniprot

Rab3A
type: Protein
entity reference: Rab3A
feature: COMPLEX PARTICIPANT BINDING FEATURE s42 sa45 216
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

Uncharacterized protein
type: ProteinReference
xref: uniprot F6R960 161
xref: PTHR12157:SF18
organism: Macaca mulatta

ncbitaxon 9598 8
type: UnificationXref
id: 9598
db: ncbitaxon

uniprot Q94392 149
type: UnificationXref
id: Q94392
db: uniprot

TRIGGER
type: Control
xref: TRIGGER
controlled: TRANSPORT_LEFT__neurotransmitter-RIGHT__neurotransmitter-_re2
control type: ACTIVATION
controller: synaptic vesicle fusion complex

RIM1alpha 2alpha s96 sa44 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: RIM1alpha/2alpha
stoichiometric coefficient: 2.0

PTHR10024:SF239
type: RelationshipXref
id: PTHR10024:SF239
db: PANTHER Family
relationship type: By Homology

Syntaxin 1A
type: ProteinReference
xref: PTHR19957:SF84
xref: uniprot Q0VFR6 118
organism: Xenopus tropicalis

uniprot F7GFB1 42
type: UnificationXref
id: F7GFB1
db: uniprot

uniprot F7FXE2 189
type: UnificationXref
id: F7FXE2
db: uniprot

Protein unc-13 homolog B
type: ProteinReference
xref: uniprot O14795 130
xref: PTHR10480:SF8
organism: Homo sapiens

axon terminus
type: CellularLocationVocabulary
xref: GO GO:0043679 3

Synaptotagmin-1
type: ProteinReference
xref: PTHR10024:SF239
xref: uniprot P21579 55
organism: Homo sapiens

uniprot F6UBB9 38
type: UnificationXref
id: F6UBB9
db: uniprot

RAB3A isoform 1
type: ProteinReference
xref: PTHR47980:SF9
xref: uniprot A0A2I3SM83 185
organism: Pan troglodytes

SNAP
type: Protein
cellular location: axon terminus
comment: SPECIES_TYPE=PROTEIN

uniprot A0A3Q1LSE5 138
type: UnificationXref
id: A0A3Q1LSE5
db: uniprot

RIM1alpha/2alpha
type: Protein
entity reference: RIM1alpha/2alpha
feature: COMPLEX PARTICIPANT BINDING FEATURE s96 sa44 214
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

uniprot P36975 173
type: UnificationXref
id: P36975
db: uniprot

SYT3 isoform 1
type: ProteinReference
xref: uniprot A0A2J8J1B3 11
organism: Pan troglodytes

Synaptobrevin
type: Protein
entity reference: Synaptobrevin
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

Synaptotagmin I
type: ProteinReference
evidence: Evidence 34
xref: PTHR10024:SF239
xref: uniprot F7GFB1 42
organism: Macaca mulatta

Syntaxin 1/2
type: Protein
entity reference: Syntaxin 1/2
cellular location: axon terminus
comment: SPECIES_TYPE=PROTEIN

Vesicle-associated membrane protein 2
type: ProteinReference
xref: PTHR45701:SF5
xref: uniprot P63026 181
organism: Bos taurus

Uncharacterized protein
type: ProteinReference
xref: uniprot F6RH55 162
organism: Macaca mulatta

Synaptophysin
type: Protein
entity reference: Synaptophysin
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

ncbitaxon 13616 36
type: UnificationXref
id: 13616
db: ncbitaxon

Synaptophysin
type: ProteinReference
xref: PTHR10306:SF10
xref: uniprot P08247 171
organism: Homo sapiens

Synaptotagmin-6
type: ProteinReference
xref: uniprot Q5T7P8 73
organism: Homo sapiens

uniprot P60877 174
type: UnificationXref
id: P60877
db: uniprot

SyNapsiN
type: ProteinReference
xref: uniprot Q8MXU3 158
organism: Caenorhabditis elegans

Regulating synaptic membrane exocytosis 1
type: ProteinReference
xref: PTHR12157:SF18
xref: uniprot F1PM67 160
organism: Canis lupus familiaris

Synaptotagmin-2
type: ProteinReference
evidence: Evidence 15
evidence: Evidence 16
xref: uniprot F6XQZ0 40
xref: PTHR10024:SF223
organism: Macaca mulatta

uniprot F7AI08 41
type: UnificationXref
id: F7AI08
db: uniprot

Synaptotagmin s56 sa35 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Synaptotagmin
stoichiometric coefficient: 2.0

Syntaxin 1 2 s23 sa17 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Syntaxin 1/2
stoichiometric coefficient: 2.0

uniprot A0A1D5RJ25 6
type: UnificationXref
id: A0A1D5RJ25
db: uniprot

Synaptosomal-associated protein 25
type: ProteinReference
xref: uniprot P60881 177
organism: Rattus norvegicus

uniprot Q8K0T7 133
type: UnificationXref
id: Q8K0T7
db: uniprot

Protein unc-13 homolog B
type: ProteinReference
xref: uniprot Q9Z1N9 136
xref: PTHR10480:SF8
organism: Mus musculus

Syntaxin-1A
type: ProteinReference
xref: uniprot Q16623 119
xref: PTHR19957:SF84
organism: Homo sapiens

uniprot A0A1D5R7T9 4
type: UnificationXref
id: A0A1D5R7T9
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A2I3RZD4 9
organism: Pan troglodytes

uniprot F1MNQ8 102
type: UnificationXref
id: F1MNQ8
db: uniprot

SNAP-25
type: Protein
entity reference: SNAP-25
feature: COMPLEX PARTICIPANT BINDING FEATURE s24 sa30 202
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

Synaptophysin
type: ProteinReference
xref: PTHR10306:SF10
xref: uniprot F6VGB3 168
organism: Macaca mulatta

ncbitaxon 9031 67
type: UnificationXref
id: 9031
db: ncbitaxon

uniprot O14795 130
type: UnificationXref
id: O14795
db: uniprot

uniprot F7GWY8 43
type: UnificationXref
id: F7GWY8
db: uniprot

uniprot Q5T7P8 73
type: UnificationXref
id: Q5T7P8
db: uniprot

Vesicle-fusing ATPase
type: ProteinReference
xref: PTHR23078:SF3
xref: uniprot Q94392 149
organism: Caenorhabditis elegans

Synaptobrevin
type: Protein
entity reference: Synaptobrevin
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

uniprot Q0V7N0 182
type: UnificationXref
id: Q0V7N0
db: uniprot

Synaptotagmin-2
type: ProteinReference
evidence: Evidence 59
xref: PTHR10024:SF223
xref: uniprot P29101 57
organism: Rattus norvegicus

Synaptotagmin 1
type: ProteinReference
evidence: Evidence 34
xref: PTHR10024:SF239
xref: uniprot F1PNW4 33
organism: Canis lupus familiaris

SNAP-25
type: ProteinReference
xref: P05778
standard name: Synaptosomal-associated protein, 25KD
comment: ENTITY_REFERENCE_ID_DESC=Synaptic_vesicle_trafficking.PROTEIN.GENERIC.SNAP-25
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Synaptosomal-associated protein, 25KD Synonym: Synonym not specified Accession: P05778
member entity reference: Synaptosomal-associated protein 25
member entity reference: Synaptosomal-associated protein

Uncharacterized protein
type: ProteinReference
xref: PTHR23078:SF3
xref: uniprot A0A3Q1LSE5 138
organism: Bos taurus

Syntaxin-2
type: ProteinReference
xref: PTHR19957:SF36
xref: uniprot Q00262 116
organism: Mus musculus

uniprot Q63666 184
type: UnificationXref
id: Q63666
db: uniprot

Synaptotagmin 6
type: ProteinReference
xref: uniprot E1BGL9 26
organism: Bos taurus

Bos taurus
type: BioSource
xref: ncbitaxon 9913 19

Uncharacterized protein
type: ProteinReference
xref: uniprot F7H4N5 107
organism: Macaca mulatta

Synapsin
type: Protein
entity reference: Synapsin
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

Macaca mulatta
type: BioSource
xref: ncbitaxon 9544 5

uniprot Q9QUL6 150
type: UnificationXref
id: Q9QUL6
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR23078:SF3
xref: uniprot E1BQU4 139
organism: Gallus gallus

Synaptotagmin-1
type: ProteinReference
evidence: Evidence 70
xref: uniprot P48018 69
xref: PTHR10024:SF239
organism: Bos taurus

Ornithorhynchus anatinus
type: BioSource
xref: ncbitaxon 9258 93

uniprot E2QT50 28
type: UnificationXref
id: E2QT50
db: uniprot

STATE_TRANSITION_LEFT__RIM1alpha_2alpha-_SNARE_complex-_Munc13-_Rab3A-_Ca2_PLUS_-_Munc18-RIGHT__synaptic_vesicle_fusion_complex-_re3
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY re3 238
participant stoichiometry: PARTICIPANT STOICHIOMETRY re3 235
participant stoichiometry: PARTICIPANT STOICHIOMETRY re3 237
participant stoichiometry: PARTICIPANT STOICHIOMETRY re3 241
participant stoichiometry: PARTICIPANT STOICHIOMETRY re3 236
participant stoichiometry: PARTICIPANT STOICHIOMETRY re3 239
participant stoichiometry: PARTICIPANT STOICHIOMETRY re3 240
left: Rab3A
left: Munc13
left: Munc18
left: RIM1alpha/2alpha
left: SNARE complex
left: Ca2+
interaction type: STATE_TRANSITION
right: synaptic vesicle fusion complex

Synaptobrevin s22 sa14 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Synaptobrevin
stoichiometric coefficient: 2.0

uniprot Q86UR5 163
type: UnificationXref
id: Q86UR5
db: uniprot

Rab3A
type: ProteinReference
xref: P05780
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Rab3A Synonym: Synonym not specified Accession: P05780
comment: ENTITY_REFERENCE_ID_DESC=Synaptic_vesicle_trafficking.PROTEIN.GENERIC.Rab3A
member entity reference: RAB3A, member RAS oncogene family
member entity reference: Ras-related protein Rab-3A
member entity reference: Uncharacterized protein
member entity reference: RAB3A isoform 1

Uncharacterized protein
type: ProteinReference
xref: PTHR47980:SF9
xref: uniprot F7ASU4 188
organism: Macaca mulatta

Uncharacterized protein
type: ProteinReference
xref: PTHR10841:SF24
xref: uniprot F6VRW8 152
organism: Macaca mulatta

ncbitaxon 10116 32
type: UnificationXref
id: 10116
db: ncbitaxon

ncbitaxon 10090 50
type: UnificationXref
id: 10090
db: ncbitaxon

Syntaxin-binding protein 1 isoform a
type: ProteinReference
xref: PTHR11679:SF35
xref: uniprot A0A1D5Q217 89
organism: Macaca mulatta

ncbitaxon 559292 144
type: UnificationXref
id: 559292
db: ncbitaxon

Rab3A
type: Protein
entity reference: Rab3A
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

Protein unc-13 homolog C
type: ProteinReference
xref: PTHR10480:SF2
xref: uniprot Q62770 131
organism: Rattus norvegicus

RAB3A, member RAS oncogene family
type: ProteinReference
xref: PTHR47980:SF9
xref: uniprot Q28H43 194
organism: Xenopus tropicalis

SYT7 isoform 3
type: ProteinReference
xref: uniprot A0A2I3S3Y2 10
organism: Pan troglodytes

SYT12 isoform 1
type: ProteinReference
xref: uniprot A0A2J8QB49 12
organism: Pan troglodytes

Uncharacterized protein
type: ProteinReference
xref: uniprot F7AI08 41
organism: Macaca mulatta

Syntaxin 2
type: ProteinReference
xref: uniprot Q08D63 117
organism: Xenopus tropicalis

Synaptobrevin
type: ProteinReference
xref: P05779
comment: ENTITY_REFERENCE_NOTES=Long Name: Synaptobrevin Synonym: Vesicle-associated membrane protein,VAMP Accession: P05779
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Synaptic_vesicle_trafficking.PROTEIN.GENERIC.Synaptobrevin
member entity reference: Vesicle-associated membrane protein 2
member entity reference: Vesicle-associated membrane protein 1

uniprot P48018 69
type: UnificationXref
id: P48018
db: uniprot

uniprot F7ED11 95
type: UnificationXref
id: F7ED11
db: uniprot

uniprot Q9Z1N9 136
type: UnificationXref
id: Q9Z1N9
db: uniprot

DISSOCIATION
type: RelationshipTypeVocabulary

Synaptotagmin-3
type: ProteinReference
xref: uniprot P40748 62
organism: Rattus norvegicus

uniprot Q24546 155
type: UnificationXref
id: Q24546
db: uniprot

uniprot F6R960 161
type: UnificationXref
id: F6R960
db: uniprot

Synaptotagmin-7
type: ProteinReference
xref: uniprot O43581 51
organism: Homo sapiens

uniprot Q16623 119
type: UnificationXref
id: Q16623
db: uniprot

uniprot P63012 193
type: UnificationXref
id: P63012
db: uniprot

Canis lupus familiaris
type: BioSource
xref: ncbitaxon 9615 29

uniprot E2R521 30
type: UnificationXref
id: E2R521
db: uniprot

Synapsin
type: Protein
entity reference: Synapsin
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

Synaptotagmin-15
type: ProteinReference
xref: uniprot Q9BQS2 82
organism: Homo sapiens

Syntaxin binding protein 1
type: ProteinReference
xref: PTHR11679:SF35
xref: uniprot F6UNB0 92
organism: Ornithorhynchus anatinus

Munc18 s94 sa43 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Munc18
stoichiometric coefficient: 2.0

Synaptotagmin 1
type: ProteinReference
evidence: Evidence 34
xref: PTHR10024:SF239
xref: uniprot F6UBB9 38
organism: Xenopus tropicalis

uniprot Q9R0N8 88
type: UnificationXref
id: Q9R0N8
db: uniprot

Gallus gallus
type: BioSource
xref: ncbitaxon 9031 67

uniprot P61264 112
type: UnificationXref
id: P61264
db: uniprot

uniprot F6VRW8 152
type: UnificationXref
id: F6VRW8
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: PTHR23078:SF3
xref: uniprot A0A1D5R978 137
organism: Macaca mulatta

eco ECO:0000304 77
type: UnificationXref
id: ECO:0000304
db: eco

Ca2+
type: SmallMolecule
feature: COMPLEX PARTICIPANT BINDING FEATURE s71 sa62 218
cellular location: synaptic vesicle
comment: SPECIES_TYPE=ION

Syntaxin-1B
type: ProteinReference
xref: PTHR19957:SF334
xref: uniprot P61265 113
organism: Rattus norvegicus

Syntaxin-1B
type: ProteinReference
xref: PTHR19957:SF334
xref: uniprot P61264 112
organism: Mus musculus

Munc13
type: Protein
entity reference: Munc13
cellular location: axon terminus
comment: SPECIES_TYPE=PROTEIN

Uncharacterized protein
type: ProteinReference
xref: PTHR23078:SF3
xref: uniprot F6PIV9 140
organism: Xenopus tropicalis

Transmitter update and vesicle docking
type: Pathway

uniprot H2R3R2 45
type: UnificationXref
id: H2R3R2
db: uniprot

NSF
type: ProteinReference
xref: P05774
standard name: N-ethylmaleimide-sensitive factor
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: N-ethylmaleimide-sensitive factor Synonym: Synonym not specified Accession: P05774
comment: ENTITY_REFERENCE_ID_DESC=Synaptic_vesicle_trafficking.PROTEIN.GENERIC.NSF
member entity reference: Uncharacterized protein
member entity reference: Vesicle-fusing ATPase 2
member entity reference: N-ethylmaleimide sensitive factor, vesicle fusing ATPase
member entity reference: Vesicle-fusing ATPase
member entity reference: Vesicle-fusing ATPase 1
member entity reference: Vesicular-fusion protein SEC18

Synaptotagmin-5
type: ProteinReference
xref: uniprot P47861 68
organism: Rattus norvegicus

uniprot F6RH55 162
type: UnificationXref
id: F6RH55
db: uniprot

uniprot Q9R189 135
type: UnificationXref
id: Q9R189
db: uniprot

STATE_TRANSITION
type: RelationshipTypeVocabulary

SYT1 isoform 2
type: ProteinReference
evidence: Evidence 34
xref: PTHR10024:SF239
xref: uniprot H2R3R2 45
organism: Pan troglodytes

PTHR19957:SF84
type: RelationshipXref
id: PTHR19957:SF84
db: PANTHER Family
relationship type: By Homology

Uncharacterized protein
type: ProteinReference
xref: PTHR19957:SF334
xref: uniprot F7DNS6 105
organism: Macaca mulatta

Synaptotagmin 3
type: ProteinReference
xref: uniprot E1BJ13 27
organism: Bos taurus

PTHR10841:SF20
type: RelationshipXref
id: PTHR10841:SF20
db: PANTHER Family
relationship type: By Homology

PTHR11679:SF35
type: RelationshipXref
id: PTHR11679:SF35
db: PANTHER Family
relationship type: By Homology

Syntaxin-1B
type: ProteinReference
xref: PTHR19957:SF334
xref: uniprot P61266 114
organism: Homo sapiens

uniprot Q64332 157
type: UnificationXref
id: Q64332
db: uniprot

uniprot Q28HP6 178
type: UnificationXref
id: Q28HP6
db: uniprot

Syntaxin-1B
type: ProteinReference
xref: PTHR19957:SF334
xref: uniprot P61267 115
organism: Bos taurus

uniprot Q0VFR6 118
type: UnificationXref
id: Q0VFR6
db: uniprot

PTHR10841:SF17
type: RelationshipXref
id: PTHR10841:SF17
db: PANTHER Family
relationship type: By Homology

UNC13C isoform 1
type: ProteinReference
xref: PTHR10480:SF2
xref: uniprot H2Q9G8 128
organism: Pan troglodytes

Protein unc-13 homolog D
type: ProteinReference
xref: uniprot Q70J99 132
xref: PTHR45999:SF3
organism: Homo sapiens

RIM1alpha/2alpha
type: Protein
entity reference: RIM1alpha/2alpha
cellular location: axon terminus
comment: SPECIES_TYPE=PROTEIN

Synaptotagmin-11
type: ProteinReference
xref: uniprot O08835 48
organism: Rattus norvegicus

uniprot P63026 181
type: UnificationXref
id: P63026
db: uniprot

PARTICIPANT STOICHIOMETRY re4 230
type: Stoichiometry
physical entity: Synaptotagmin
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY re4 231
type: Stoichiometry
physical entity: Synaptobrevin
stoichiometric coefficient: 1.0

SNAP 25 s54 sa41 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: SNAP-25
stoichiometric coefficient: 2.0

uniprot E1BEH9 25
type: UnificationXref
id: E1BEH9
db: uniprot

PARTICIPANT STOICHIOMETRY re4 232
type: Stoichiometry
physical entity: Syntaxin 1/2
stoichiometric coefficient: 1.0

Uncharacterized protein
type: ProteinReference
xref: PTHR11679:SF35
xref: uniprot F6XL12 94
organism: Monodelphis domestica

Synapsin-2 isoform IIa
type: ProteinReference
xref: PTHR10841:SF20
xref: uniprot F6TA37 151
organism: Macaca mulatta

PARTICIPANT STOICHIOMETRY re4 233
type: Stoichiometry
physical entity: SNAP-25
stoichiometric coefficient: 1.0

STX1A isoform 3
type: ProteinReference
xref: PTHR19957:SF84
xref: uniprot H2QUQ1 108
organism: Pan troglodytes

uniprot F7DFQ7 169
type: UnificationXref
id: F7DFQ7
db: uniprot

PARTICIPANT STOICHIOMETRY re4 234
type: Stoichiometry
physical entity: SNARE complex
stoichiometric coefficient: 1.0

uniprot P60880 176
type: UnificationXref
id: P60880
db: uniprot

uniprot P40748 62
type: UnificationXref
id: P40748
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A1D5R7T9 4
organism: Macaca mulatta

Caenorhabditis briggsae
type: BioSource
xref: ncbitaxon 6238 23

uniprot F1N7B7 159
type: UnificationXref
id: F1N7B7
db: uniprot

Caenorhabditis elegans
type: BioSource
xref: ncbitaxon 6239 61

uniprot F7DNS6 105
type: UnificationXref
id: F7DNS6
db: uniprot

Syntaxin 1/2
type: Protein
entity reference: Syntaxin 1/2
feature: COMPLEX PARTICIPANT BINDING FEATURE s53 sa39 208
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

Vesicle-fusing ATPase
type: ProteinReference
xref: PTHR23078:SF3
xref: uniprot P46459 145
organism: Homo sapiens

Syntaxin 1B
type: ProteinReference
xref: PTHR19957:SF334
xref: uniprot F7EP58 106
organism: Xenopus tropicalis

PTHR10841:SF24
type: RelationshipXref
id: PTHR10841:SF24
db: PANTHER Family
relationship type: By Homology

uniprot Q00262 116
type: UnificationXref
id: Q00262
db: uniprot

Synaptotagmin-15
type: ProteinReference
xref: uniprot Q8C6N3 74
organism: Mus musculus

uniprot P61764 98
type: UnificationXref
id: P61764
db: uniprot

Synaptotagmin
type: Protein
entity reference: Synaptotagmin
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

uniprot P61765 99
type: UnificationXref
id: P61765
db: uniprot

Munc13
type: Protein
entity reference: Munc13
feature: COMPLEX PARTICIPANT BINDING FEATURE s100 sa84 220
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

Syntaxin-1A isoform 1
type: ProteinReference
xref: PTHR19957:SF84
xref: uniprot A0A1D5QEM1 100
organism: Macaca mulatta

Synaptophysin
type: ProteinReference
xref: PTHR10306:SF10
xref: uniprot P07825 170
organism: Rattus norvegicus

PTHR19957:SF334
type: RelationshipXref
id: PTHR19957:SF334
db: PANTHER Family
relationship type: By Homology

Synapsin-1
type: ProteinReference
xref: uniprot O88935 153
xref: PTHR10841:SF24
organism: Mus musculus

uniprot P46096 63
type: UnificationXref
id: P46096
db: uniprot

Vesicle-fusing ATPase
type: ProteinReference
xref: PTHR23078:SF3
xref: uniprot P46460 146
organism: Mus musculus

Vesicle-fusing ATPase 1
type: ProteinReference
xref: uniprot P46461 147
xref: PTHR23078:SF3
organism: Drosophila melanogaster

uniprot A0A1D5R978 137
type: UnificationXref
id: A0A1D5R978
db: uniprot

eco ECO:0000250 14
type: UnificationXref
id: ECO:0000250
db: eco

Synaptotagmin-1
type: ProteinReference
xref: uniprot P34693 60
organism: Caenorhabditis elegans

Synaptotagmin-1
type: ProteinReference
xref: uniprot P47191 66
organism: Gallus gallus

Uncharacterized protein
type: ProteinReference
xref: PTHR23078:SF3
xref: uniprot F7F4B9 141
organism: Monodelphis domestica

SYT5 protein
type: ProteinReference
xref: uniprot A4IFJ2 21
organism: Bos taurus

uniprot A0A2I3S3Y2 10
type: UnificationXref
id: A0A2I3S3Y2
db: uniprot

PARTICIPANT STOICHIOMETRY re3 238
type: Stoichiometry
physical entity: Rab3A
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY re3 239
type: Stoichiometry
physical entity: Ca2+
stoichiometric coefficient: 1.0

uniprot F1PNW4 33
type: UnificationXref
id: F1PNW4
db: uniprot

PARTICIPANT STOICHIOMETRY re3 236
type: Stoichiometry
physical entity: SNARE complex
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY re3 237
type: Stoichiometry
physical entity: Munc13
stoichiometric coefficient: 1.0

Synaptotagmin-11
type: ProteinReference
xref: uniprot Q9BT88 83
organism: Homo sapiens

uniprot H2QD95 142
type: UnificationXref
id: H2QD95
db: uniprot

uniprot F7ASU4 188
type: UnificationXref
id: F7ASU4
db: uniprot

Evidence 15
type: Evidence
evidence code: ISS
comment: SPACC SYT2_MOUSE

Uncharacterized protein
type: ProteinReference
xref: PTHR10480:SF8
xref: uniprot F1P9F6 126
organism: Canis lupus familiaris

uniprot P18759 143
type: UnificationXref
id: P18759
db: uniprot

Evidence 16
type: Evidence
evidence code: ISS
comment: SPACC SYT2_RAT

PARTICIPANT STOICHIOMETRY re3 235
type: Stoichiometry
physical entity: RIM1alpha/2alpha
stoichiometric coefficient: 1.0

uniprot O08835 48
type: UnificationXref
id: O08835
db: uniprot

TRANSPORT
type: RelationshipTypeVocabulary

Ca2 PLUS s71 sa62 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Ca2+
stoichiometric coefficient: 2.0

Synaptotagmin-2
type: ProteinReference
xref: uniprot Q8N9I0 76
xref: PTHR10024:SF223
organism: Homo sapiens

Synaptotagmin-3
type: ProteinReference
xref: uniprot O35681 49
organism: Mus musculus

RCA
type: EvidenceCodeVocabulary
xref: eco ECO:0000245 58

uniprot O08599 96
type: UnificationXref
id: O08599
db: uniprot

PARTICIPANT STOICHIOMETRY re3 240
type: Stoichiometry
physical entity: Munc18
stoichiometric coefficient: 1.0

Synaptotagmin-like 3
type: ProteinReference
xref: uniprot E9PU77 31
organism: Rattus norvegicus

PARTICIPANT STOICHIOMETRY re3 241
type: Stoichiometry
physical entity: synaptic vesicle fusion complex
stoichiometric coefficient: 1.0

uniprot Q8C6N3 74
type: UnificationXref
id: Q8C6N3
db: uniprot

Synaptotagmin 2
type: ProteinReference
evidence: Evidence 15
evidence: Evidence 16
xref: uniprot A0A3Q1LZP6 18
xref: PTHR10024:SF223
organism: Bos taurus

Synaptotagmin-11
type: ProteinReference
xref: uniprot G7MDX8 44
organism: Macaca mulatta

uniprot H2QDW4 129
type: UnificationXref
id: H2QDW4
db: uniprot

uniprot A0A1D5QEM1 100
type: UnificationXref
id: A0A1D5QEM1
db: uniprot

synaptic vesicle fusion complex
type: Complex
component stoichiometry: Syntaxin 1 2 s53 sa39 STOICHIOMETRY ID COMPLEX
component stoichiometry: Ca2 PLUS s71 sa62 STOICHIOMETRY ID COMPLEX
component stoichiometry: RIM1alpha 2alpha s96 sa44 STOICHIOMETRY ID COMPLEX
component stoichiometry: Munc18 s94 sa43 STOICHIOMETRY ID COMPLEX
component stoichiometry: Synaptotagmin s56 sa35 STOICHIOMETRY ID COMPLEX
component stoichiometry: Rab3A s42 sa45 STOICHIOMETRY ID COMPLEX
component stoichiometry: SNAP 25 s54 sa41 STOICHIOMETRY ID COMPLEX
component stoichiometry: Synaptobrevin s52 sa36 STOICHIOMETRY ID COMPLEX
component stoichiometry: Munc13 s100 sa84 STOICHIOMETRY ID COMPLEX
component: SNAP-25
component: Synaptobrevin
component: Synaptotagmin
component: Rab3A
component: Ca2+
component: Syntaxin 1/2
component: Munc18
component: Munc13
component: RIM1alpha/2alpha
feature: COMPLEX BINDING FEATURE s51 csa3 209
feature: COMPLEX BINDING FEATURE s51 csa3 215
feature: COMPLEX BINDING FEATURE s51 csa3 213
feature: COMPLEX BINDING FEATURE s51 csa3 203
feature: COMPLEX BINDING FEATURE s51 csa3 207
feature: COMPLEX BINDING FEATURE s51 csa3 211
feature: COMPLEX BINDING FEATURE s51 csa3 219
feature: COMPLEX BINDING FEATURE s51 csa3 205
feature: COMPLEX BINDING FEATURE s51 csa3 217
cellular location: synaptic vesicle

uniprot Q62770 131
type: UnificationXref
id: Q62770
db: uniprot

Munc18
type: ProteinReference
xref: P05770
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Munc18 Synonym: STXBP1,Syntaxin-binding protein 1 Accession: P05770
comment: ENTITY_REFERENCE_ID_DESC=Synaptic_vesicle_trafficking.PROTEIN.GENERIC.Munc18
member entity reference: Syntaxin-binding protein 1
member entity reference: Uncharacterized protein
member entity reference: STXBP1 isoform 10
member entity reference: Syntaxin-binding protein 1 isoform a
member entity reference: Syntaxin binding protein 1

uniprot P21521 52
type: UnificationXref
id: P21521
db: uniprot

Syntaxin 2
type: ProteinReference
xref: uniprot F1MNQ8 102
organism: Bos taurus

uniprot Q28H43 194
type: UnificationXref
id: Q28H43
db: uniprot

Rab3A s42 sa45 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Rab3A
stoichiometric coefficient: 2.0

uniprot Q63537 156
type: UnificationXref
id: Q63537
db: uniprot

Vesicle-associated membrane protein 1
type: ProteinReference
xref: PTHR45701:SF1
xref: uniprot Q63666 184
organism: Rattus norvegicus

Synaptophysin
type: ProteinReference
xref: uniprot F1N548 166
xref: PTHR10306:SF10
organism: Bos taurus

CATALYSIS
type: Catalysis
controlled: DISSOCIATION_LEFT__synaptic_vesicle_fusion_complex-RIGHT__Synaptobrevin-_RIM1alpha_2alpha-_Syntaxin_1_2-_Munc13-_SNAP_25-_Rab3A-_Munc18-_Synaptotagmin-_re5
controller: NSF

ISS
type: EvidenceCodeVocabulary
xref: eco ECO:0000250 14

Evidence 34
type: Evidence
evidence code: ISS
comment: SPACC SYT1_BOVIN

uniprot E1BQU4 139
type: UnificationXref
id: E1BQU4
db: uniprot

uniprot Q8N9I0 76
type: UnificationXref
id: Q8N9I0
db: uniprot

Syntaxin-1A
type: ProteinReference
xref: PTHR19957:SF84
xref: uniprot P32851 110
organism: Rattus norvegicus

GO GO:0043679 3
type: UnificationXref
id: GO:0043679
db: GO

Syntaxin binding protein 1
type: ProteinReference
xref: uniprot F1P7D2 91
xref: PTHR11679:SF35
organism: Canis lupus familiaris

uniprot Q62442 183
type: UnificationXref
id: Q62442
db: uniprot

Munc13
type: ProteinReference
xref: P05773
comment: ENTITY_REFERENCE_NOTES=Long Name: Munc13 Synonym: UNC13 Accession: P05773
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Synaptic_vesicle_trafficking.PROTEIN.GENERIC.Munc13
member entity reference: UNC13C isoform 1
member entity reference: Protein unc-13 homolog C
member entity reference: Protein unc-13 homolog B
member entity reference: UNC13D isoform 1
member entity reference: Uncharacterized protein
member entity reference: Protein unc-13 homolog D
member entity reference: Unc-13 homolog B

uniprot P32856 111
type: UnificationXref
id: P32856
db: uniprot

uniprot P47861 68
type: UnificationXref
id: P47861
db: uniprot

Synaptotagmin-2
type: ProteinReference
evidence: Evidence 65
xref: PTHR10024:SF223
xref: uniprot P46097 64
organism: Mus musculus

Synaptotagmin-1
type: ProteinReference
xref: PTHR10024:SF239
xref: uniprot P46096 63
organism: Mus musculus

Syntaxin-2
type: ProteinReference
xref: uniprot P32856 111
organism: Homo sapiens

Monodelphis domestica
type: BioSource
xref: ncbitaxon 13616 36

uniprot F6TAG2 37
type: UnificationXref
id: F6TAG2
db: uniprot

Regulating synaptic membrane exocytosis protein 2
type: ProteinReference
xref: uniprot Q9EQZ7 164
organism: Mus musculus

uniprot P61763 97
type: UnificationXref
id: P61763
db: uniprot

uniprot Q8IV01 75
type: UnificationXref
id: Q8IV01
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A3Q1MKW3 20
organism: Bos taurus

uniprot A0A2J8J1B3 11
type: UnificationXref
id: A0A2J8J1B3
db: uniprot

PTHR19305:SF5
type: RelationshipXref
id: PTHR19305:SF5
db: PANTHER Family
relationship type: By Homology

Evidence 59
type: Evidence
evidence code: RCA
comment: SPACC SYT2_RAT

uniprot A0A2J8QB49 12
type: UnificationXref
id: A0A2J8QB49
db: uniprot

SNARE complex
type: Complex
component stoichiometry: SNAP 25 s24 sa30 STOICHIOMETRY ID COMPLEX
component stoichiometry: Synaptobrevin s22 sa14 STOICHIOMETRY ID COMPLEX
component stoichiometry: Synaptotagmin s21 sa13 STOICHIOMETRY ID COMPLEX
component stoichiometry: Syntaxin 1 2 s23 sa17 STOICHIOMETRY ID COMPLEX
component: Synaptotagmin
component: Synaptobrevin
component: SNAP-25
component: Syntaxin 1/2
feature: COMPLEX BINDING FEATURE s20 csa1 195
feature: COMPLEX BINDING FEATURE s20 csa1 201
feature: COMPLEX BINDING FEATURE s20 csa1 197
feature: COMPLEX BINDING FEATURE s20 csa1 199
cellular location: synaptic vesicle

uniprot Q62277 172
type: UnificationXref
id: Q62277
db: uniprot

STXBP1 isoform 10
type: ProteinReference
xref: PTHR11679:SF35
xref: uniprot A0A2I3TBU2 90
organism: Pan troglodytes

Uncharacterized protein
type: ProteinReference
xref: uniprot F6TZ81 187
organism: Monodelphis domestica

PANTHER Pathway P05734 1
type: UnificationXref
id: P05734
db: PANTHER Pathway

SNAP-25
type: Protein
entity reference: SNAP-25
feature: COMPLEX PARTICIPANT BINDING FEATURE s54 sa41 210
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

Ras-related protein Rab-3A
type: ProteinReference
xref: uniprot P20336 191
xref: PTHR47980:SF9
organism: Homo sapiens

Protein unc-13 homolog D
type: ProteinReference
xref: uniprot B2RUP2 125
xref: PTHR45999:SF3
organism: Mus musculus

HETERODIMER_ASSOCIATION_LEFT__Synaptotagmin-_Synaptobrevin-_Syntaxin_1_2-_SNAP_25-RIGHT__SNARE_complex-_re4
type: ComplexAssembly
spontaneous: true
conversion direction: LEFT_TO_RIGHT
xref: HETERODIMER ASSOCIATION
participant stoichiometry: PARTICIPANT STOICHIOMETRY re4 232
participant stoichiometry: PARTICIPANT STOICHIOMETRY re4 234
participant stoichiometry: PARTICIPANT STOICHIOMETRY re4 231
participant stoichiometry: PARTICIPANT STOICHIOMETRY re4 230
participant stoichiometry: PARTICIPANT STOICHIOMETRY re4 233
left: Synaptobrevin
left: Syntaxin 1/2
left: Synaptotagmin
left: SNAP-25
interaction type: HETERODIMER_ASSOCIATION
right: SNARE complex

uniprot Q925B4 79
type: UnificationXref
id: Q925B4
db: uniprot

Synaptotagmin-like protein 3
type: ProteinReference
xref: uniprot Q99N48 80
organism: Mus musculus

Synaptotagmin-5
type: ProteinReference
xref: uniprot O00445 46
organism: Homo sapiens

DISSOCIATION
type: InteractionVocabulary

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A3Q1LZT1 124
xref: PTHR10480:SF8
organism: Bos taurus

Synaptotagmin 3
type: ProteinReference
xref: uniprot E2R521 30
organism: Canis lupus familiaris

uniprot B2RUP2 125
type: UnificationXref
id: B2RUP2
db: uniprot

uniprot E2RIA5 186
type: UnificationXref
id: E2RIA5
db: uniprot

uniprot Q99N48 80
type: UnificationXref
id: Q99N48
db: uniprot

PTHR12157:SF18
type: RelationshipXref
id: PTHR12157:SF18
db: PANTHER Family
relationship type: By Homology

Synaptotagmin
type: Protein
entity reference: Synaptotagmin
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

Syntaxin-1A
type: ProteinReference
xref: PTHR19957:SF84
xref: uniprot O35526 109
organism: Mus musculus

uniprot Q08D63 117
type: UnificationXref
id: Q08D63
db: uniprot

Synaptophysin
type: Protein
entity reference: Synaptophysin
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

uniprot Q5R1X1 179
type: UnificationXref
id: Q5R1X1
db: uniprot

uniprot P29101 57
type: UnificationXref
id: P29101
db: uniprot

Homo sapiens
type: BioSource
xref: ncbitaxon 9606 47

PTHR23078:SF3
type: RelationshipXref
id: PTHR23078:SF3
db: PANTHER Family
relationship type: By Homology

uniprot P61265 113
type: UnificationXref
id: P61265
db: uniprot

RAB3A, member RAS oncogene family
type: ProteinReference
xref: PTHR47980:SF9
xref: uniprot E2RIA5 186
organism: Canis lupus familiaris

uniprot F7EP58 106
type: UnificationXref
id: F7EP58
db: uniprot

Synaptotagmin 5
type: ProteinReference
xref: uniprot E2QT50 28
organism: Canis lupus familiaris

uniprot P47191 66
type: UnificationXref
id: P47191
db: uniprot

Evidence 70
type: Evidence
evidence code: RCA
comment: SPACC SYT1_BOVIN

Synaptobrevin
type: Protein
entity reference: Synaptobrevin
feature: COMPLEX PARTICIPANT BINDING FEATURE s52 sa36 206
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

Synaptosomal-associated protein
type: ProteinReference
xref: uniprot Q28HP6 178
xref: PTHR19305:SF5
organism: Xenopus tropicalis

STX2 isoform 2
type: ProteinReference
xref: uniprot A0A2I3S3S5 101
organism: Pan troglodytes

Vesicular-fusion protein SEC18
type: ProteinReference
xref: PTHR23078:SF3
xref: uniprot P18759 143
organism: Saccharomyces cerevisiae

Synaptotagmin-1
type: ProteinReference
xref: PTHR10024:SF239
xref: uniprot P21707 56
organism: Rattus norvegicus

PTHR45701:SF5
type: RelationshipXref
id: PTHR45701:SF5
db: PANTHER Family
relationship type: By Homology

uniprot Q9BQG1 81
type: UnificationXref
id: Q9BQG1
db: uniprot

PTHR45701:SF1
type: RelationshipXref
id: PTHR45701:SF1
db: PANTHER Family
relationship type: By Homology

NSF
type: Protein
entity reference: NSF
cellular location: axon terminus
comment: SPECIES_TYPE=PROTEIN

uniprot A0A2I3RAD9 7
type: UnificationXref
id: A0A2I3RAD9
db: uniprot

TRANSPORT_LEFT__neurotransmitter-RIGHT__neurotransmitter-_re2
type: TransportWithBiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: TRANSPORT
participant stoichiometry: PARTICIPANT STOICHIOMETRY re2 242
participant stoichiometry: PARTICIPANT STOICHIOMETRY re2 243
left: neurotransmitter
interaction type: TRANSPORT
right: neurotransmitter

uniprot A0A2I3SM83 185
type: UnificationXref
id: A0A2I3SM83
db: uniprot

Unc-13 homolog B
type: ProteinReference
xref: uniprot A0A2I3TIQ6 123
xref: PTHR10480:SF8
organism: Pan troglodytes

Ca2+
type: SmallMolecule
cellular location: axon terminus
comment: SPECIES_TYPE=ION

uniprot P46461 147
type: UnificationXref
id: P46461
db: uniprot

Evidence 65
type: Evidence
evidence code: RCA
comment: SPACC SYT2_MOUSE

Danio rerio
type: BioSource
xref: ncbitaxon 7955 121

PTHR47980:SF9
type: RelationshipXref
id: PTHR47980:SF9
db: PANTHER Family
relationship type: By Homology

CATALYSIS
type: Catalysis
controlled: DISSOCIATION_LEFT__synaptic_vesicle_fusion_complex-RIGHT__Synaptobrevin-_RIM1alpha_2alpha-_Syntaxin_1_2-_Munc13-_SNAP_25-_Rab3A-_Munc18-_Synaptotagmin-_re5
controller: SNAP

Protein unc-13 homolog C
type: ProteinReference
xref: PTHR10480:SF2
xref: uniprot Q8K0T7 133
organism: Mus musculus

uniprot Q8NB66 134
type: UnificationXref
id: Q8NB66
db: uniprot

PARTICIPANT STOICHIOMETRY re2 242
type: Stoichiometry
physical entity: neurotransmitter
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY re2 243
type: Stoichiometry
physical entity: neurotransmitter
stoichiometric coefficient: 1.0

Rab3A
type: Protein
entity reference: Rab3A
cellular location: axon terminus
comment: SPECIES_TYPE=PROTEIN

Synapsin-2
type: ProteinReference
xref: PTHR10841:SF20
xref: uniprot Q63537 156
organism: Rattus norvegicus

uniprot P61266 114
type: UnificationXref
id: P61266
db: uniprot

neurotransmitter
type: SmallMolecule
cellular location: synaptic vesicle
comment: SPECIES_TYPE=SIMPLE_MOLECULE

SyNapTotagmin
type: ProteinReference
xref: uniprot P91493 71
organism: Caenorhabditis elegans

Syntaxin 1B
type: ProteinReference
xref: PTHR19957:SF334
xref: uniprot F6WJB1 104
organism: Monodelphis domestica

uniprot P61267 115
type: UnificationXref
id: P61267
db: uniprot

uniprot F6TZ81 187
type: UnificationXref
id: F6TZ81
db: uniprot

Syntaxin 1 2 s53 sa39 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Syntaxin 1/2
stoichiometric coefficient: 2.0

Regulating synaptic membrane exocytosis 1
type: ProteinReference
xref: PTHR12157:SF18
xref: uniprot F1N7B7 159
organism: Bos taurus

uniprot F1PM67 160
type: UnificationXref
id: F1PM67
db: uniprot

Synaptotagmin
type: ProteinReference
xref: P05769
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Synaptic_vesicle_trafficking.PROTEIN.GENERIC.Synaptotagmin
comment: ENTITY_REFERENCE_NOTES=Long Name: Synaptotagmin Synonym: p65 Accession: P05769
member entity reference: Synaptotagmin 1
member entity reference: Synaptotagmin-2
member entity reference: Synaptotagmin-12
member entity reference: Synaptotagmin-1
member entity reference: SYT12 isoform 1
member entity reference: Synaptotagmin-3
member entity reference: Synaptotagmin-8
member entity reference: Synaptotagmin-11
member entity reference: Synaptotagmin 2
member entity reference: SYT1 isoform 2
member entity reference: SYT11 isoform 1
member entity reference: Uncharacterized protein
member entity reference: Synaptotagmin-like 3
member entity reference: SYT7 isoform 3
member entity reference: SyNapTotagmin
member entity reference: Synaptotagmin 3
member entity reference: Synaptotagmin-6
member entity reference: Synaptotagmin-7
member entity reference: Synaptotagmin 6
member entity reference: Synaptotagmin-15
member entity reference: Protein CBR-SNT-1
member entity reference: SYT3 isoform 1
member entity reference: Protein CBR-SNT-4
member entity reference: Synaptotagmin-5
member entity reference: SYT2 isoform 1
member entity reference: SYT5 protein
member entity reference: Synaptotagmin I
member entity reference: Synaptotagmin 12
member entity reference: Synaptotagmin-like protein 3
member entity reference: Synaptotagmin 5
member entity reference: Synaptotagmin XII

Synaptosomal-associated protein 25
type: ProteinReference
xref: uniprot P36975 173
xref: PTHR19305:SF14
organism: Drosophila melanogaster

uniprot F1P7D2 91
type: UnificationXref
id: F1P7D2
db: uniprot

Synaptophysin
type: ProteinReference
xref: uniprot Q62277 172
xref: PTHR10306:SF10
organism: Mus musculus

uniprot Q1MTI1 120
type: UnificationXref
id: Q1MTI1
db: uniprot

uniprot P63011 192
type: UnificationXref
id: P63011
db: uniprot

uniprot Q9BQS2 82
type: UnificationXref
id: Q9BQS2
db: uniprot

Synaptophysin
type: ProteinReference
xref: PTHR10306:SF10
xref: uniprot F1Q4G9 167
organism: Canis lupus familiaris

SYT2 isoform 1
type: ProteinReference
evidence: Evidence 15
evidence: Evidence 16
xref: PTHR10024:SF223
xref: uniprot A0A2J8QWL9 13
organism: Pan troglodytes

By Homology
type: RelationshipTypeVocabulary

Synaptotagmin 1
type: ProteinReference
xref: uniprot P21521 52
xref: PTHR10024:SF227
organism: Drosophila melanogaster

HETERODIMER_ASSOCIATION
type: InteractionVocabulary

uniprot A0A2I3TIQ6 123
type: UnificationXref
id: A0A2I3TIQ6
db: uniprot

SNARE complex dissembly
type: Pathway

Uncharacterized protein
type: ProteinReference
xref: uniprot F6TLL7 127
xref: PTHR10480:SF8
organism: Macaca mulatta

Uncharacterized protein
type: ProteinReference
xref: uniprot F6QFD5 35
organism: Monodelphis domestica

uniprot H2Q9G8 128
type: UnificationXref
id: H2Q9G8
db: uniprot

TAS
type: EvidenceCodeVocabulary
xref: eco ECO:0000304 77

uniprot F6XQZ0 40
type: UnificationXref
id: F6XQZ0
db: uniprot

Protein CBR-SNT-4
type: ProteinReference
xref: uniprot A8XG70 24
organism: Caenorhabditis briggsae

uniprot P60881 177
type: UnificationXref
id: P60881
db: uniprot

neurotransmitter
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot P34693 60
type: UnificationXref
id: P34693
db: uniprot

ncbitaxon 9615 29
type: UnificationXref
id: 9615
db: ncbitaxon

Fusion
type: Pathway

uniprot P21707 56
type: UnificationXref
id: P21707
db: uniprot

SNAP 25 s24 sa30 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: SNAP-25
stoichiometric coefficient: 2.0

uniprot E9PU77 31
type: UnificationXref
id: E9PU77
db: uniprot

uniprot F7F4B9 141
type: UnificationXref
id: F7F4B9
db: uniprot

Regulating synaptic membrane exocytosis protein 2
type: ProteinReference
xref: uniprot Q9JIS1 165
organism: Rattus norvegicus

Vesicle-fusing ATPase
type: ProteinReference
xref: uniprot Q9QUL6 150
xref: PTHR23078:SF3
organism: Rattus norvegicus

Vesicle-associated membrane protein 1
type: ProteinReference
xref: PTHR45701:SF1
xref: uniprot Q62442 183
organism: Mus musculus

Rattus norvegicus
type: BioSource
xref: ncbitaxon 10116 32

Munc18
type: Protein
entity reference: Munc18
feature: COMPLEX PARTICIPANT BINDING FEATURE s94 sa43 212
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

uniprot F6TLL7 127
type: UnificationXref
id: F6TLL7
db: uniprot

uniprot P91493 71
type: UnificationXref
id: P91493
db: uniprot

uniprot P23763 180
type: UnificationXref
id: P23763
db: uniprot

Synapsin
type: ProteinReference
xref: P05775
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Synaptic_vesicle_trafficking.PROTEIN.GENERIC.Synapsin
comment: ENTITY_REFERENCE_NOTES=Long Name: Synapsin Synonym: Syn1,Brain protein 4.1 Accession: P05775
member entity reference: Synapsin-1
member entity reference: Synapsin-2 isoform IIa
member entity reference: Synapsin-2
member entity reference: Synapsin
member entity reference: SyNapsiN
member entity reference: Uncharacterized protein

eco ECO:0000245 58
type: UnificationXref
id: ECO:0000245
db: eco

uniprot A8XCL2 22
type: UnificationXref
id: A8XCL2
db: uniprot

ncbitaxon 9258 93
type: UnificationXref
id: 9258
db: ncbitaxon

uniprot A0A2J8QWL9 13
type: UnificationXref
id: A0A2J8QWL9
db: uniprot

uniprot Q9EQZ7 164
type: UnificationXref
id: Q9EQZ7
db: uniprot

RAB3A, member RAS oncogene family
type: ProteinReference
xref: PTHR47980:SF9
xref: uniprot F7FXE2 189
organism: Ornithorhynchus anatinus

Vesicle-associated membrane protein 1
type: ProteinReference
xref: PTHR45701:SF1
xref: uniprot P23763 180
organism: Homo sapiens

uniprot Q9R0N3 84
type: UnificationXref
id: Q9R0N3
db: uniprot

PARTICIPANT STOICHIOMETRY re5 225
type: Stoichiometry
physical entity: Munc13
stoichiometric coefficient: 1.0

PTHR45999:SF3
type: RelationshipXref
id: PTHR45999:SF3
db: PANTHER Family
relationship type: By Homology

PARTICIPANT STOICHIOMETRY re5 226
type: Stoichiometry
physical entity: SNAP-25
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY re5 223
type: Stoichiometry
physical entity: RIM1alpha/2alpha
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY re5 224
type: Stoichiometry
physical entity: Syntaxin 1/2
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY re5 229
type: Stoichiometry
physical entity: Synaptotagmin
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY re5 227
type: Stoichiometry
physical entity: Rab3A
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY re5 228
type: Stoichiometry
physical entity: Munc18
stoichiometric coefficient: 1.0

uniprot O88935 153
type: UnificationXref
id: O88935
db: uniprot

Protein CBR-SNT-1
type: ProteinReference
xref: uniprot A8XCL2 22
organism: Caenorhabditis briggsae

Protein unc-13 homolog D
type: ProteinReference
xref: uniprot Q9R189 135
xref: PTHR45999:SF3
organism: Rattus norvegicus

STATE_TRANSITION
type: InteractionVocabulary

PARTICIPANT STOICHIOMETRY re5 221
type: Stoichiometry
physical entity: synaptic vesicle fusion complex
stoichiometric coefficient: 1.0

uniprot P46459 145
type: UnificationXref
id: P46459
db: uniprot

PARTICIPANT STOICHIOMETRY re5 222
type: Stoichiometry
physical entity: Synaptobrevin
stoichiometric coefficient: 1.0

TRANSPORT
type: InteractionVocabulary

Synaptobrevin s52 sa36 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Synaptobrevin
stoichiometric coefficient: 2.0

P05772
type: UnificationXref
id: P05772
db: PANTHER Pathway Component

Vesicle-associated membrane protein 1
type: ProteinReference
xref: PTHR45701:SF1
xref: uniprot Q0V7N0 182
organism: Bos taurus

P05774
type: UnificationXref
id: P05774
db: PANTHER Pathway Component

P05773
type: UnificationXref
id: P05773
db: PANTHER Pathway Component

P05776
type: UnificationXref
id: P05776
db: PANTHER Pathway Component

P05775
type: UnificationXref
id: P05775
db: PANTHER Pathway Component

P05778
type: UnificationXref
id: P05778
db: PANTHER Pathway Component

P05777
type: UnificationXref
id: P05777
db: PANTHER Pathway Component

uniprot O43581 51
type: UnificationXref
id: O43581
db: uniprot

uniprot Q70J99 132
type: UnificationXref
id: Q70J99
db: uniprot

Priming
type: Pathway

uniprot Q9JIS1 165
type: UnificationXref
id: Q9JIS1
db: uniprot

uniprot P32851 110
type: UnificationXref
id: P32851
db: uniprot

P05770
type: UnificationXref
id: P05770
db: PANTHER Pathway Component

uniprot Q9R0N6 86
type: UnificationXref
id: Q9R0N6
db: uniprot

Syntaxin 1/2
type: Protein
entity reference: Syntaxin 1/2
feature: COMPLEX PARTICIPANT BINDING FEATURE s23 sa17 200
cellular location: synaptic vesicle
comment: SPECIES_TYPE=PROTEIN

SYT11 isoform 1
type: ProteinReference
xref: uniprot A0A2I3RAD9 7
organism: Pan troglodytes

uniprot F1PR71 103
type: UnificationXref
id: F1PR71
db: uniprot

P05769
type: UnificationXref
id: P05769
db: PANTHER Pathway Component

uniprot P20336 191
type: UnificationXref
id: P20336
db: uniprot

uniprot F6TA37 151
type: UnificationXref
id: F6TA37
db: uniprot

ncbitaxon 9544 5
type: UnificationXref
id: 9544
db: ncbitaxon

PTHR19957:SF36
type: RelationshipXref
id: PTHR19957:SF36
db: PANTHER Family
relationship type: By Homology

uniprot F6WJB1 104
type: UnificationXref
id: F6WJB1
db: uniprot

uniprot E1BJ13 27
type: UnificationXref
id: E1BJ13
db: uniprot

P05780
type: UnificationXref
id: P05780
db: PANTHER Pathway Component

Munc18
type: Protein
entity reference: Munc18
cellular location: axon terminus
comment: SPECIES_TYPE=PROTEIN

uniprot A0A1D5QBF1 122
type: UnificationXref
id: A0A1D5QBF1
db: uniprot

uniprot O00445 46
type: UnificationXref
id: O00445
db: uniprot

Synaptotagmin s21 sa13 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: Synaptotagmin
stoichiometric coefficient: 2.0

Synaptotagmin-3
type: ProteinReference
xref: uniprot Q9BQG1 81
organism: Homo sapiens

Syntaxin-binding protein 1
type: ProteinReference
xref: PTHR11679:SF35
xref: uniprot F7ED11 95
organism: Xenopus tropicalis

Synaptic_vesicle_trafficking
type: Pathway
pathway component: HETERODIMER_ASSOCIATION_LEFT__Synaptotagmin-_Synaptobrevin-_Syntaxin_1_2-_SNAP_25-RIGHT__SNARE_complex-_re4
pathway component: TRANSPORT_LEFT__neurotransmitter-RIGHT__neurotransmitter-_re2
pathway component: DISSOCIATION_LEFT__synaptic_vesicle_fusion_complex-RIGHT__Synaptobrevin-_RIM1alpha_2alpha-_Syntaxin_1_2-_Munc13-_SNAP_25-_Rab3A-_Munc18-_Synaptotagmin-_re5
pathway component: STATE_TRANSITION_LEFT__RIM1alpha_2alpha-_SNARE_complex-_Munc13-_Rab3A-_Ca2_PLUS_-_Munc18-RIGHT__synaptic_vesicle_fusion_complex-_re3
xref: PANTHER Pathway P05734 1
comment: MODEL_NOTES=Synaptic vesicle trafficking at the presynaptic active zone is a key process regulating synatpci transmission. The increase of Ca++ concentration triggers the docking of synatptic vesicle to the presynatpci membrane. Vesicle proteins, such as synaptotagmin and synaptobrevin, interact with syntaxin and SNAP25 on the presynaptic membrane to for the SNARE complex. The vesicle membrane then fuses with the presynptic membrane, which results in neurotransmitter release to the synatpci cleft. Subsequently, the SNARE complex is disassembled, and the vesicle is recycled. Medline=16707259 Medline=12154365 Medline=12600315 Medline=15217342

ncbitaxon 9606 47
type: UnificationXref
id: 9606
db: ncbitaxon

uniprot F1Q4G9 167
type: UnificationXref
id: F1Q4G9
db: uniprot

P05779
type: UnificationXref
id: P05779
db: PANTHER Pathway Component

uniprot Q920N7 78
type: UnificationXref
id: Q920N7
db: uniprot

Syntaxin-binding protein 1
type: ProteinReference
xref: PTHR11679:SF35
xref: uniprot P61765 99
organism: Rattus norvegicus

HETERODIMER_ASSOCIATION
type: RelationshipTypeVocabulary

Syntaxin-binding protein 1
type: ProteinReference
xref: PTHR11679:SF35
xref: uniprot P61764 98
organism: Homo sapiens

uniprot P46097 64
type: UnificationXref
id: P46097
db: uniprot

Syntaxin-binding protein 1
type: ProteinReference
xref: PTHR11679:SF35
xref: uniprot P61763 97
organism: Bos taurus

uniprot P54351 148
type: UnificationXref
id: P54351
db: uniprot

uniprot Q8MXU3 158
type: UnificationXref
id: Q8MXU3
db: uniprot

uniprot A0A1D5Q217 89
type: UnificationXref
id: A0A1D5Q217
db: uniprot

uniprot A0A3Q1LZP6 18
type: UnificationXref
id: A0A3Q1LZP6
db: uniprot

uniprot A8XG70 24
type: UnificationXref
id: A8XG70
db: uniprot

Synaptophysin
type: ProteinReference
xref: P05777
comment: ENTITY_REFERENCE_ID_DESC=Synaptic_vesicle_trafficking.PROTEIN.GENERIC.Synaptophysin
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Synaptophysin Synonym: Synonym not specified Accession: P05777
member entity reference: Synaptophysin

IDA
type: EvidenceCodeVocabulary

Syntaxin 1/2
type: ProteinReference
xref: P05772
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=Long Name: Syntaxin 1/2 Synonym: Stx1/2 Accession: P05772
comment: ENTITY_REFERENCE_ID_DESC=Synaptic_vesicle_trafficking.PROTEIN.GENERIC.Syntaxin 1/2
member entity reference: Syntaxin-2
member entity reference: Syntaxin 1B
member entity reference: Uncharacterized protein
member entity reference: Syntaxin-1A
member entity reference: Syntaxin-1A isoform 1
member entity reference: STX1A isoform 3
member entity reference: Syntaxin 2
member entity reference: Syntaxin-1B
member entity reference: STX2 isoform 2
member entity reference: Syntaxin 1A

uniprot F1P9F6 126
type: UnificationXref
id: F1P9F6
db: uniprot