PARTICIPANT STOICHIOMETRY r101 27
type: Stoichiometry
physical entity: Pi
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r101 26
type: Stoichiometry
physical entity: Diacylglycerol
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r101 25
type: Stoichiometry
physical entity: Phosphatidate
stoichiometric coefficient: 1.0

STATE_TRANSITION_LEFT__ATP-RIGHT__PPi-_Cyclic_AMP-_r93
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r93 45
participant stoichiometry: PARTICIPANT STOICHIOMETRY r93 46
participant stoichiometry: PARTICIPANT STOICHIOMETRY r93 44
left: ATP
interaction type: STATE_TRANSITION
right: Cyclic-AMP
right: PPi

ADP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q7JR83 16
type: UnificationXref
id: Q7JR83
db: uniprot

STATE_TRANSITION_LEFT__Protein_Kinase_A-RIGHT__Protein_Kinase_A-_r91
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r91 51
participant stoichiometry: PARTICIPANT STOICHIOMETRY r91 50
left: Protein Kinase A
interaction type: STATE_TRANSITION
right: Protein Kinase A

uniprot F7EWI0 3
type: UnificationXref
id: F7EWI0
db: uniprot

STATE_TRANSITION_LEFT__Protein_Kinase_A-_Cyclic_AMP-RIGHT__Protein_Kinase_A-_r92
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r92 47
participant stoichiometry: PARTICIPANT STOICHIOMETRY r92 49
participant stoichiometry: PARTICIPANT STOICHIOMETRY r92 48
left: Protein Kinase A
left: Cyclic-AMP
interaction type: STATE_TRANSITION
right: Protein Kinase A

uniprot P07867 7
type: UnificationXref
id: P07867
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__H2O-_Monoacylglycerol-RIGHT__Fatty_acid-_Glycerol-_r105
controller: Monoacylglycerol lipase

ncbitaxon 9598 6
type: UnificationXref
id: 9598
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r103 67
type: Stoichiometry
physical entity: Diacylglycerol
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r103 66
type: Stoichiometry
physical entity: Fatty acid
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r103 65
type: Stoichiometry
physical entity: Triacylglycerol
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r103 64
type: Stoichiometry
physical entity: H2O
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r105 56
type: Stoichiometry
physical entity: H2O
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r105 57
type: Stoichiometry
physical entity: Monoacylglycerol
stoichiometric coefficient: 1.0

Macaca mulatta
type: BioSource
xref: ncbitaxon 9544 4

PARTICIPANT STOICHIOMETRY r105 58
type: Stoichiometry
physical entity: Fatty acid
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r105 59
type: Stoichiometry
physical entity: Glycerol
stoichiometric coefficient: 1.0

H2O
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Adrenaline Noradrenaline
type: Protein
comment: SPECIES_TYPE=PROTEIN

Mus musculus
type: BioSource
xref: ncbitaxon 10090 13

Triacylglycerol metabolism
type: Pathway
pathway component: STATE_TRANSITION_LEFT__Protein_Kinase_A-RIGHT__Protein_Kinase_A-_r91
pathway component: STATE_TRANSITION_LEFT__Fatty_acids-_ATP__PLUS____CoA_SH-RIGHT__ATP__PLUS____PPi-_Fatty_acyl_CoA-_r106
pathway component: STATE_TRANSITION_LEFT__H2O-_Monoacylglycerol-RIGHT__Fatty_acid-_Glycerol-_r105
pathway component: STATE_TRANSITION_LEFT__Insulin-_Cyclic_AMP-RIGHT__5_QUOTE_SINGLE_AMP-_r95
pathway component: STATE_TRANSITION_LEFT__H2O-_Phosphatidate-RIGHT__Diacylglycerol-_Pi-_r101
pathway component: STATE_TRANSITION_LEFT__Fatty_acyl_CoA-_Glycerol_3_P-RIGHT__Phosphatidate-_CoA_SH-_r100
pathway component: STATE_TRANSITION_LEFT__Triacylglycerol_lipase-RIGHT__Pi-_Triacylglycerol_lipase-_r98
pathway component: STATE_TRANSITION_LEFT__Fatty_acyl_CoA-_Diacylglycerol-RIGHT__CoA_SH-_Triacylglycerol-_r102
pathway component: KNOWN_TRANSITION_OMITTED_LEFT__Glucose-RIGHT__Glycerol_3_P-_r99
pathway component: STATE_TRANSITION_LEFT__H2O-_Diacylglycerol-RIGHT__Fatty_acid-_Monoacylglycerol-_r104
pathway component: STATE_TRANSITION_LEFT__H2O-_Triacylglycerol-RIGHT__Fatty_acid-_Diacylglycerol-_r103
pathway component: STATE_TRANSITION_LEFT__ATP-_Triacylglycerol_lipase-RIGHT__ADP-_Triacylglycerol_lipase-_r114
pathway component: STATE_TRANSITION_LEFT__ATP-RIGHT__PPi-_Cyclic_AMP-_r93
pathway component: STATE_TRANSITION_LEFT__Protein_Kinase_A-_Cyclic_AMP-RIGHT__Protein_Kinase_A-_r92
xref: PANTHER Pathway P02782 1
comment: MODEL_NOTES=

ATP + PPi
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r114 37
type: Stoichiometry
physical entity: ATP
stoichiometric coefficient: 1.0

STATE_TRANSITION_LEFT__H2O-_Diacylglycerol-RIGHT__Fatty_acid-_Monoacylglycerol-_r104
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r104 60
participant stoichiometry: PARTICIPANT STOICHIOMETRY r104 61
participant stoichiometry: PARTICIPANT STOICHIOMETRY r104 63
participant stoichiometry: PARTICIPANT STOICHIOMETRY r104 62
left: H2O
left: Diacylglycerol
interaction type: STATE_TRANSITION
right: Monoacylglycerol
right: Fatty acid

PARTICIPANT STOICHIOMETRY r114 39
type: Stoichiometry
physical entity: ADP
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r114 38
type: Stoichiometry
physical entity: Triacylglycerol lipase
stoichiometric coefficient: 1.0

Drosophila melanogaster
type: BioSource
xref: ncbitaxon 7227 17

ATP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Diacylglycerol acyltransferase
type: Protein
comment: SPECIES_TYPE=PROTEIN

Phosphodiesterase
type: Protein
comment: SPECIES_TYPE=PROTEIN

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Fatty_acyl_CoA-_Glycerol_3_P-RIGHT__Phosphatidate-_CoA_SH-_r100
controller: Glycerophosphate acyltransferase

uniprot H2QGG6 5
type: UnificationXref
id: H2QGG6
db: uniprot

P03205
type: UnificationXref
id: P03205
db: PANTHER Pathway Component

PARTICIPANT STOICHIOMETRY r114 40
type: Stoichiometry
physical entity: Triacylglycerol lipase
stoichiometric coefficient: 1.0

Pi
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Lipase E, hormone sensitive type
type: ProteinReference
xref: uniprot H2QGG6 5
organism: Pan troglodytes

Glycerophosphate acyltransferase
type: Protein
comment: SPECIES_TYPE=PROTEIN

Rattus norvegicus
type: BioSource
xref: ncbitaxon 10116 8

ncbitaxon 9606 10
type: UnificationXref
id: 9606
db: ncbitaxon

uniprot P54310 14
type: UnificationXref
id: P54310
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Triacylglycerol_lipase-RIGHT__Pi-_Triacylglycerol_lipase-_r98
controller: Phosphatase

STATE_TRANSITION_LEFT__Insulin-_Cyclic_AMP-RIGHT__5_QUOTE_SINGLE_AMP-_r95
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r95 41
participant stoichiometry: PARTICIPANT STOICHIOMETRY r95 42
participant stoichiometry: PARTICIPANT STOICHIOMETRY r95 43
left: Insulin
left: Cyclic-AMP
interaction type: STATE_TRANSITION
right: 5'-AMP

Hepatic triacylglycerol lipase
type: ProteinReference
xref: uniprot P07867 7
organism: Rattus norvegicus

5'-AMP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PANTHER Pathway P02782 1
type: UnificationXref
id: P02782
db: PANTHER Pathway

Hormone-sensitive lipase
type: ProteinReference
xref: uniprot Q05469 15
organism: Homo sapiens

uniprot Q966P1 18
type: UnificationXref
id: Q966P1
db: uniprot

ncbitaxon 7227 17
type: UnificationXref
id: 7227
db: ncbitaxon

Phosphotidate phosphohydrolase
type: Protein
comment: SPECIES_TYPE=PROTEIN

Hormone-sensitive lipase, isoform A
type: ProteinReference
xref: uniprot Q7JR83 16
organism: Drosophila melanogaster

ncbitaxon 10116 8
type: UnificationXref
id: 10116
db: ncbitaxon

Triacylglycerol
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r100 28
type: Stoichiometry
physical entity: Fatty acyl-CoA
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r100 29
type: Stoichiometry
physical entity: Glycerol-3-P
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r95 43
type: Stoichiometry
physical entity: 5'-AMP
stoichiometric coefficient: 1.0

uniprot P27656 12
type: UnificationXref
id: P27656
db: uniprot

PARTICIPANT STOICHIOMETRY r100 30
type: Stoichiometry
physical entity: Phosphatidate
stoichiometric coefficient: 1.0

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__H2O-_Phosphatidate-RIGHT__Diacylglycerol-_Pi-_r101
controller: Phosphotidate phosphohydrolase

PARTICIPANT STOICHIOMETRY r95 41
type: Stoichiometry
physical entity: Insulin
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r95 42
type: Stoichiometry
physical entity: Cyclic-AMP
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r91 50
type: Stoichiometry
physical entity: Protein Kinase A
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r91 51
type: Stoichiometry
physical entity: Protein Kinase A
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r100 31
type: Stoichiometry
physical entity: CoA-SH
stoichiometric coefficient: 1.0

Glycerol-3-P
type: SmallMolecule
cellular location: Glycolysis c2
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Monoacylglycerol lipase
type: Protein
comment: SPECIES_TYPE=PROTEIN

Protein Kinase A
type: Protein
feature: ACTIVE 2
comment: SPECIES_TYPE=PROTEIN

PARTICIPANT STOICHIOMETRY r93 44
type: Stoichiometry
physical entity: ATP
stoichiometric coefficient: 1.0

KNOWN_TRANSITION_OMITTED
type: RelationshipTypeVocabulary

PARTICIPANT STOICHIOMETRY r93 45
type: Stoichiometry
physical entity: PPi
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r93 46
type: Stoichiometry
physical entity: Cyclic-AMP
stoichiometric coefficient: 1.0

Monoacylglycerol
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Fatty acids
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot P15304 11
type: UnificationXref
id: P15304
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__H2O-_Diacylglycerol-RIGHT__Fatty_acid-_Monoacylglycerol-_r104
controller: Diacylglycerol lipase

Hormone-sensitive lipase
type: ProteinReference
xref: uniprot P54310 14
organism: Mus musculus

Pan troglodytes
type: BioSource
xref: ncbitaxon 9598 6

STATE_TRANSITION_LEFT__H2O-_Triacylglycerol-RIGHT__Fatty_acid-_Diacylglycerol-_r103
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r103 66
participant stoichiometry: PARTICIPANT STOICHIOMETRY r103 67
participant stoichiometry: PARTICIPANT STOICHIOMETRY r103 65
participant stoichiometry: PARTICIPANT STOICHIOMETRY r103 64
left: Triacylglycerol
left: H2O
interaction type: STATE_TRANSITION
right: Diacylglycerol
right: Fatty acid

Glycerol
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Hormone-sensitive lipase
type: ProteinReference
xref: uniprot P15304 11
organism: Rattus norvegicus

Glycolysis c2
type: CellularLocationVocabulary
comment: Glycolysis

STATE_TRANSITION
type: InteractionVocabulary

STATE_TRANSITION
type: RelationshipTypeVocabulary

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__ATP-_Triacylglycerol_lipase-RIGHT__ADP-_Triacylglycerol_lipase-_r114
controller: Protein Kinase A

Fatty acid
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q05469 15
type: UnificationXref
id: Q05469
db: uniprot

PARTICIPANT STOICHIOMETRY r104 63
type: Stoichiometry
physical entity: Monoacylglycerol
stoichiometric coefficient: 1.0

Phosphatidate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r104 62
type: Stoichiometry
physical entity: Fatty acid
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r104 61
type: Stoichiometry
physical entity: Diacylglycerol
stoichiometric coefficient: 1.0

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__ATP-RIGHT__PPi-_Cyclic_AMP-_r93
controller: Adrenaline Noradrenaline

Phosphatase
type: Protein
comment: SPECIES_TYPE=PROTEIN

PARTICIPANT STOICHIOMETRY r104 60
type: Stoichiometry
physical entity: H2O
stoichiometric coefficient: 1.0

KNOWN_TRANSITION_OMITTED_LEFT__Glucose-RIGHT__Glycerol_3_P-_r99
type: Conversion
conversion direction: LEFT_TO_RIGHT
xref: KNOWN TRANSITION OMITTED
participant stoichiometry: PARTICIPANT STOICHIOMETRY r99 32
participant stoichiometry: PARTICIPANT STOICHIOMETRY r99 33
left: Glucose
interaction type: KNOWN_TRANSITION_OMITTED
right: Glycerol-3-P

Protein Kinase A
type: Protein
comment: SPECIES_TYPE=PROTEIN

ncbitaxon 6239 19
type: UnificationXref
id: 6239
db: ncbitaxon

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__H2O-_Triacylglycerol-RIGHT__Fatty_acid-_Diacylglycerol-_r103
controller: Triacylglycerol lipase

Fatty acyl-CoA synthetase
type: Protein
comment: SPECIES_TYPE=PROTEIN

ncbitaxon 9544 4
type: UnificationXref
id: 9544
db: ncbitaxon

Uncharacterized protein
type: ProteinReference
xref: uniprot F7EWI0 3
organism: Macaca mulatta

ATP + CoA-SH
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Fatty_acyl_CoA-_Diacylglycerol-RIGHT__CoA_SH-_Triacylglycerol-_r102
controller: Diacylglycerol acyltransferase

Triacylglycerol lipase
type: Protein
entity reference: Triacylglycerol lipase
feature: ACTIVE 2
comment: SPECIES_TYPE=PROTEIN

PARTICIPANT STOICHIOMETRY r106 55
type: Stoichiometry
physical entity: Fatty acyl-CoA
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r106 53
type: Stoichiometry
physical entity: ATP + CoA-SH
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r106 54
type: Stoichiometry
physical entity: ATP + PPi
stoichiometric coefficient: 1.0

KNOWN_TRANSITION_OMITTED
type: InteractionVocabulary

STATE_TRANSITION_LEFT__H2O-_Monoacylglycerol-RIGHT__Fatty_acid-_Glycerol-_r105
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r105 56
participant stoichiometry: PARTICIPANT STOICHIOMETRY r105 58
participant stoichiometry: PARTICIPANT STOICHIOMETRY r105 57
participant stoichiometry: PARTICIPANT STOICHIOMETRY r105 59
left: H2O
left: Monoacylglycerol
interaction type: STATE_TRANSITION
right: Fatty acid
right: Glycerol

PARTICIPANT STOICHIOMETRY r106 52
type: Stoichiometry
physical entity: Fatty acids
stoichiometric coefficient: 1.0

Homo sapiens
type: BioSource
xref: ncbitaxon 9606 10

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Fatty_acyl_CoA-_Glycerol_3_P-RIGHT__Phosphatidate-_CoA_SH-_r100
controller: Acylglycerophosphate acyltransferase

Acylglycerophosphate acyltransferase
type: Protein
comment: SPECIES_TYPE=PROTEIN

Uncharacterized protein
type: ProteinReference
xref: uniprot Q966P1 18
organism: Caenorhabditis elegans

STATE_TRANSITION_LEFT__Fatty_acyl_CoA-_Diacylglycerol-RIGHT__CoA_SH-_Triacylglycerol-_r102
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r102 22
participant stoichiometry: PARTICIPANT STOICHIOMETRY r102 20
participant stoichiometry: PARTICIPANT STOICHIOMETRY r102 23
participant stoichiometry: PARTICIPANT STOICHIOMETRY r102 21
left: Fatty acyl-CoA
left: Diacylglycerol
interaction type: STATE_TRANSITION
right: Triacylglycerol
right: CoA-SH

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Fatty_acids-_ATP__PLUS____CoA_SH-RIGHT__ATP__PLUS____PPi-_Fatty_acyl_CoA-_r106
controller: Fatty acyl-CoA synthetase

Hepatic triacylglycerol lipase
type: ProteinReference
xref: uniprot P11150 9
organism: Homo sapiens

STATE_TRANSITION_LEFT__Fatty_acids-_ATP__PLUS____CoA_SH-RIGHT__ATP__PLUS____PPi-_Fatty_acyl_CoA-_r106
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r106 55
participant stoichiometry: PARTICIPANT STOICHIOMETRY r106 52
participant stoichiometry: PARTICIPANT STOICHIOMETRY r106 54
participant stoichiometry: PARTICIPANT STOICHIOMETRY r106 53
left: Fatty acids
left: ATP + CoA-SH
interaction type: STATE_TRANSITION
right: Fatty acyl-CoA
right: ATP + PPi

Triacylglycerol lipase
type: ProteinReference
xref: P03205
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: Triacylglycerol lipase Synonym: Synonym not specified Accession: P03205
comment: ENTITY_REFERENCE_ID_DESC=Triacylglycerol metabolism.PROTEIN.GENERIC.Triacylglycerol_br_lipase
member entity reference: Lipase E, hormone sensitive type
member entity reference: Hormone-sensitive lipase, isoform A
member entity reference: Hormone-sensitive lipase
member entity reference: Uncharacterized protein
member entity reference: Hepatic triacylglycerol lipase

Triacylglycerol lipase
type: Protein
entity reference: Triacylglycerol lipase
comment: SPECIES_TYPE=PROTEIN

Caenorhabditis elegans
type: BioSource
xref: ncbitaxon 6239 19

PARTICIPANT STOICHIOMETRY r92 47
type: Stoichiometry
physical entity: Protein Kinase A
stoichiometric coefficient: 1.0

Diacylglycerol lipase
type: Protein
comment: SPECIES_TYPE=PROTEIN

Cyclic-AMP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r92 49
type: Stoichiometry
physical entity: Protein Kinase A
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r92 48
type: Stoichiometry
physical entity: Cyclic-AMP
stoichiometric coefficient: 1.0

STATE_TRANSITION_LEFT__ATP-_Triacylglycerol_lipase-RIGHT__ADP-_Triacylglycerol_lipase-_r114
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r114 39
participant stoichiometry: PARTICIPANT STOICHIOMETRY r114 38
participant stoichiometry: PARTICIPANT STOICHIOMETRY r114 37
participant stoichiometry: PARTICIPANT STOICHIOMETRY r114 40
left: ATP
left: Triacylglycerol lipase
interaction type: STATE_TRANSITION
right: ADP
right: Triacylglycerol lipase

CoA-SH
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PPi
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ACTIVE 2
type: EntityFeature
comment: Active state

ncbitaxon 10090 13
type: UnificationXref
id: 10090
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r101 24
type: Stoichiometry
physical entity: H2O
stoichiometric coefficient: 1.0

uniprot P11150 9
type: UnificationXref
id: P11150
db: uniprot

Glucose
type: SmallMolecule
cellular location: Glycolysis c2
comment: SPECIES_TYPE=SIMPLE_MOLECULE

STATE_TRANSITION_LEFT__Fatty_acyl_CoA-_Glycerol_3_P-RIGHT__Phosphatidate-_CoA_SH-_r100
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r100 31
participant stoichiometry: PARTICIPANT STOICHIOMETRY r100 29
participant stoichiometry: PARTICIPANT STOICHIOMETRY r100 28
participant stoichiometry: PARTICIPANT STOICHIOMETRY r100 30
left: Fatty acyl-CoA
left: Glycerol-3-P
interaction type: STATE_TRANSITION
right: CoA-SH
right: Phosphatidate

Diacylglycerol
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

STATE_TRANSITION_LEFT__H2O-_Phosphatidate-RIGHT__Diacylglycerol-_Pi-_r101
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r101 27
participant stoichiometry: PARTICIPANT STOICHIOMETRY r101 24
participant stoichiometry: PARTICIPANT STOICHIOMETRY r101 25
participant stoichiometry: PARTICIPANT STOICHIOMETRY r101 26
left: Phosphatidate
left: H2O
interaction type: STATE_TRANSITION
right: Pi
right: Diacylglycerol

PARTICIPANT STOICHIOMETRY r98 34
type: Stoichiometry
physical entity: Triacylglycerol lipase
stoichiometric coefficient: 1.0

Hepatic triacylglycerol lipase
type: ProteinReference
xref: uniprot P27656 12
organism: Mus musculus

PARTICIPANT STOICHIOMETRY r98 35
type: Stoichiometry
physical entity: Pi
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r99 32
type: Stoichiometry
physical entity: Glucose
stoichiometric coefficient: 1.0

Fatty acyl-CoA
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r102 21
type: Stoichiometry
physical entity: Diacylglycerol
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r98 36
type: Stoichiometry
physical entity: Triacylglycerol lipase
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r99 33
type: Stoichiometry
physical entity: Glycerol-3-P
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r102 20
type: Stoichiometry
physical entity: Fatty acyl-CoA
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r102 23
type: Stoichiometry
physical entity: Triacylglycerol
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r102 22
type: Stoichiometry
physical entity: CoA-SH
stoichiometric coefficient: 1.0

STATE_TRANSITION_LEFT__Triacylglycerol_lipase-RIGHT__Pi-_Triacylglycerol_lipase-_r98
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r98 34
participant stoichiometry: PARTICIPANT STOICHIOMETRY r98 36
participant stoichiometry: PARTICIPANT STOICHIOMETRY r98 35
left: Triacylglycerol lipase
interaction type: STATE_TRANSITION
right: Triacylglycerol lipase
right: Pi

Insulin
type: Protein
comment: SPECIES_TYPE=PROTEIN

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Insulin-_Cyclic_AMP-RIGHT__5_QUOTE_SINGLE_AMP-_r95
controller: Phosphodiesterase