Tryptophan synthase beta chain
type: ProteinReference
xref: uniprot Q9RVT1 86
organism: Deinococcus radiodurans

N-(5'-phosphoribosyl)anthranilate isomerase
type: ProteinReference
xref: uniprot O84331 120
organism: Chlamydia trachomatis

Halobacterium salinarum
type: BioSource
xref: ncbitaxon 64091 50

uniprot Q8LPI9 129
type: UnificationXref
id: Q8LPI9
db: uniprot

uniprot P74130 21
type: UnificationXref
id: P74130
db: uniprot

ncbitaxon 1111708 16
type: UnificationXref
id: 1111708
db: ncbitaxon

N-(5'-phosphoribosyl)anthranilate isomerase
type: ProteinReference
xref: uniprot Q8AAD7 127
organism: Bacteroides thetaiotaomicron

Indole-3-glycerol phosphate synthase
type: ProteinReference
xref: uniprot Q8AAD6 113
organism: Bacteroides thetaiotaomicron

Phosphribosyl anthranilate isomerase
type: ProteinReference
xref: P03211
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: Phosphribosyl anthranilate isomerase Synonym: Synonym not specified Accession: P03211
comment: ENTITY_REFERENCE_ID_DESC=Tryptophan biosynthesis.PROTEIN.GENERIC.Phosphribosyl_br_anthranilate_br_isomerase
member entity reference: N-(5'-phosphoribosyl)anthranilate isomerase
member entity reference: N-(5'-phosphoribosyl)anthranilate isomerase 1, chloroplastic
member entity reference: N-(5'-phosphoribosyl)anthranilate isomerase 3, chloroplastic
member entity reference: N-(5'-phosphoribosyl)anthranilate isomerase 2, chloroplastic

Anthranilate phosphoribosyltransferase
type: ProteinReference
xref: uniprot Q8AAD5 101
organism: Bacteroides thetaiotaomicron

Anthranilate synthase component II
type: ProteinReference
xref: uniprot Q8AAD4 35
organism: Bacteroides thetaiotaomicron

PARTICIPANT STOICHIOMETRY r2 136
type: Stoichiometry
physical entity: PPi
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r2 137
type: Stoichiometry
physical entity: 5-phosphoribosyl anthranilate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r2 134
type: Stoichiometry
physical entity: 2-aminobenzoate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r2 135
type: Stoichiometry
physical entity: PRPP
stoichiometric coefficient: 1.0

Gloeobacter violaceus
type: BioSource
xref: ncbitaxon 251221 32

Anthranilate phosphoribosyltransferase
type: ProteinReference
xref: uniprot Q8F708 102
organism: Leptospira interrogans

Tryptophan synthase B
type: ProteinReference
xref: P03208
comment: ENTITY_REFERENCE_ID_DESC=Tryptophan biosynthesis.PROTEIN.GENERIC.Tryptophan synthase B
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: Tryptophan synthase B Synonym: Synonym not specified Accession: P03208
member entity reference: Tryptophan synthase beta chain
member entity reference: Tryptophan synthase beta chain 1
member entity reference: Tryptophan synthase
member entity reference: Tryptophan synthase beta chain 2
member entity reference: Tryptophan synthase beta subunit (TrpB), authentic frameshift

indole-3-glycerol phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q9HPG5 49
type: UnificationXref
id: Q9HPG5
db: uniprot

uniprot Q9RY28 131
type: UnificationXref
id: Q9RY28
db: uniprot

ncbitaxon 64091 50
type: UnificationXref
id: 64091
db: ncbitaxon

uniprot O66576 91
type: UnificationXref
id: O66576
db: uniprot

uniprot P03964 109
type: UnificationXref
id: P03964
db: uniprot

ncbitaxon 83332 23
type: UnificationXref
id: 83332
db: ncbitaxon

uniprot Q8RI82 39
type: UnificationXref
id: Q8RI82
db: uniprot

Chlamydia trachomatis
type: BioSource
xref: ncbitaxon 272561 67

Thermotoga maritima
type: BioSource
xref: ncbitaxon 243274 25

uniprot Q9RTJ5 104
type: UnificationXref
id: Q9RTJ5
db: uniprot

Anthranilate synthase beta subunit
type: ProteinReference
xref: uniprot Q9FE37 47
organism: Arabidopsis thaliana

Tryptophan synthase beta subunit (TrpB), authentic frameshift
type: ProteinReference
xref: uniprot Q8ZZH7 83
organism: Pyrobaculum aerophilum

G-3-P
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Anthranilate phosphoribosyltransferase
type: ProteinReference
xref: uniprot Q7UYS5 100
organism: Rhodopirellula baltica

Indole-3-glycerol phosphate synthase
type: ProteinReference
xref: P03210
comment: ENTITY_REFERENCE_NOTES= Long Name: Indole-3-glycerol phosphate synthase Synonym: Synonym not specified Accession: P03210
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Tryptophan biosynthesis.PROTEIN.GENERIC.Indole-3-glycerol_br_phosphate synthase
member entity reference: Indole-3-glycerol phosphate synthase
member entity reference: Indole-3-glycerol phosphate synthase 1
member entity reference: Indole-3-glycerol phosphate synthase 2
member entity reference: AT5g48220/MIF21_11

ncbitaxon 227321 77
type: UnificationXref
id: 227321
db: ncbitaxon

uniprot Q42440 122
type: UnificationXref
id: Q42440
db: uniprot

Anthranilate synthase component II
type: ProteinReference
xref: uniprot Q7NM84 31
organism: Gloeobacter violaceus

Saccharomyces cerevisiae
type: BioSource
xref: ncbitaxon 559292 12

uniprot O67409 65
type: UnificationXref
id: O67409
db: uniprot

Synechocystis
type: BioSource
xref: ncbitaxon 1111708 16

Anthranilate synthase beta subunit 1, chloroplastic
type: ProteinReference
xref: uniprot Q42565 27
organism: Arabidopsis thaliana

ncbitaxon 559292 12
type: UnificationXref
id: 559292
db: ncbitaxon

uniprot Q9I2Y1 51
type: UnificationXref
id: Q9I2Y1
db: uniprot

Tryptophan synthase beta chain 1
type: ProteinReference
xref: uniprot P50909 73
organism: Thermotoga maritima

P03211
type: UnificationXref
id: P03211
db: PANTHER Pathway Component

P03210
type: UnificationXref
id: P03210
db: PANTHER Pathway Component

uniprot P28819 19
type: UnificationXref
id: P28819
db: uniprot

uniprot F4I5H7 89
type: UnificationXref
id: F4I5H7
db: uniprot

uniprot P00912 121
type: UnificationXref
id: P00912
db: uniprot

ncbitaxon 367110 10
type: UnificationXref
id: 367110
db: ncbitaxon

Anthranilate synthase component 1
type: ProteinReference
xref: uniprot Q9S2U2 54
organism: Streptomyces coelicolor

uniprot Q92370 46
type: UnificationXref
id: Q92370
db: uniprot

uniprot P00903 7
type: UnificationXref
id: P00903
db: uniprot

uniprot O66923 64
type: UnificationXref
id: O66923
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__chorismate-_glutamine-RIGHT__2_aminobenzoate-_glutamate-_pyruvate-_r1
controller: Anthranilate synthase

uniprot Q58475 29
type: UnificationXref
id: Q58475
db: uniprot

P03208
type: UnificationXref
id: P03208
db: PANTHER Pathway Component

uniprot O13831 63
type: UnificationXref
id: O13831
db: uniprot

Anthranilate phosphoribosyltransferase
type: ProteinReference
xref: uniprot Q7NGU2 97
organism: Gloeobacter violaceus

P03206
type: UnificationXref
id: P03206
db: PANTHER Pathway Component

STATE_TRANSITION_LEFT__chorismate-_glutamine-RIGHT__2_aminobenzoate-_glutamate-_pyruvate-_r1
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 142
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 138
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 139
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 141
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 140
left: chorismate
left: glutamine
interaction type: STATE_TRANSITION
right: 2-aminobenzoate
right: pyruvate
right: glutamate

P03209
type: UnificationXref
id: P03209
db: PANTHER Pathway Component

ncbitaxon 3702 28
type: UnificationXref
id: 3702
db: ncbitaxon

uniprot P20580 17
type: UnificationXref
id: P20580
db: uniprot

uniprot Q7NML1 125
type: UnificationXref
id: Q7NML1
db: uniprot

Anthranilate phosphoribosyl transferase
type: Protein
entity reference: Anthranilate phosphoribosyl transferase
comment: SPECIES_TYPE=PROTEIN

uniprot Q7RZ63 99
type: UnificationXref
id: Q7RZ63
db: uniprot

uniprot P03963 13
type: UnificationXref
id: P03963
db: uniprot

STATE_TRANSITION_LEFT__5_phosphoribosyl_anthranilate-RIGHT__O_carboxyphenylamino_1_deoxyribuloose_5_phosphate-_r3
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 133
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 132
left: 5-phosphoribosyl anthranilate
interaction type: STATE_TRANSITION
right: O-carboxyphenylamino 1-deoxyribuloose-5-phosphate

Tryptophan synthase beta chain
type: ProteinReference
xref: uniprot O05625 62
organism: Streptomyces coelicolor

Neurospora crassa
type: BioSource
xref: ncbitaxon 367110 10

uniprot Q8AAD7 127
type: UnificationXref
id: Q8AAD7
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Serine-_indole-RIGHT__tryptophan-_H2O-_r6
controller: Tryptophan synthase B

Tryptophan synthase
type: ProteinReference
xref: uniprot A8IFZ9 60
organism: Chlamydomonas reinhardtii

uniprot Q7NGU2 97
type: UnificationXref
id: Q7NGU2
db: uniprot

ncbitaxon 224324 3
type: UnificationXref
id: 224324
db: ncbitaxon

Thermococcus kodakaraensis
type: BioSource
xref: ncbitaxon 69014 57

uniprot Q9YGB3 56
type: UnificationXref
id: Q9YGB3
db: uniprot

Bacteroides thetaiotaomicron
type: BioSource
xref: ncbitaxon 226186 36

Phosphribosyl anthranilate isomerase
type: Protein
entity reference: Phosphribosyl anthranilate isomerase
comment: SPECIES_TYPE=PROTEIN

uniprot Q7UKJ7 112
type: UnificationXref
id: Q7UKJ7
db: uniprot

Anthranilate phosphoribosyltransferase
type: ProteinReference
xref: uniprot P07285 95
organism: Saccharomyces cerevisiae

Tryptophan synthase beta chain
type: ProteinReference
xref: uniprot Q60179 78
organism: Methanocaldococcus jannaschii

Anthranilate phosphoribosyltransferase
type: ProteinReference
xref: uniprot Q7RZ63 99
organism: Neurospora crassa

uniprot Q7NHI0 111
type: UnificationXref
id: Q7NHI0
db: uniprot

uniprot O94582 5
type: UnificationXref
id: O94582
db: uniprot

ncbitaxon 208964 18
type: UnificationXref
id: 208964
db: ncbitaxon

uniprot Q9Z4W9 106
type: UnificationXref
id: Q9Z4W9
db: uniprot

uniprot Q8AAD4 35
type: UnificationXref
id: Q8AAD4
db: uniprot

N-(5'-phosphoribosyl)anthranilate isomerase
type: ProteinReference
xref: uniprot Q7UMC3 126
organism: Rhodopirellula baltica

Schizosaccharomyces pombe
type: BioSource
xref: ncbitaxon 284812 6

STATE_TRANSITION_LEFT__2_aminobenzoate-_PRPP-RIGHT__PPi-_5_phosphoribosyl_anthranilate-_r2
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 137
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 135
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 134
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 136
left: 2-aminobenzoate
left: PRPP
interaction type: STATE_TRANSITION
right: 5-phosphoribosyl anthranilate
right: PPi

PRPP
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

N-(5'-phosphoribosyl)anthranilate isomerase 3, chloroplastic
type: ProteinReference
xref: uniprot Q8LPI9 129
organism: Arabidopsis thaliana

PARTICIPANT STOICHIOMETRY r5 147
type: Stoichiometry
physical entity: indole-3-glycerol phosphate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r5 148
type: Stoichiometry
physical entity: G-3-P
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r5 149
type: Stoichiometry
physical entity: indole
stoichiometric coefficient: 1.0

Aminodeoxychorismate synthase component 1
type: ProteinReference
xref: uniprot P28820 20
organism: Bacillus subtilis

uniprot Q8ZZH7 83
type: UnificationXref
id: Q8ZZH7
db: uniprot

Anthranilate synthase component II
type: ProteinReference
xref: uniprot Q7UTD9 33
organism: Rhodopirellula baltica

AT5g48220/MIF21_11
type: ProteinReference
xref: uniprot Q9LUB2 116
organism: Arabidopsis thaliana

glutamate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Aminodeoxychorismate/anthranilate synthase component 2
type: ProteinReference
xref: uniprot P28819 19
organism: Bacillus subtilis

uniprot Q08653 24
type: UnificationXref
id: Q08653
db: uniprot

chorismate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot P07600 70
type: UnificationXref
id: P07600
db: uniprot

ncbitaxon 243232 30
type: UnificationXref
id: 243232
db: ncbitaxon

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__5_phosphoribosyl_anthranilate-RIGHT__O_carboxyphenylamino_1_deoxyribuloose_5_phosphate-_r3
controller: Phosphribosyl anthranilate isomerase

uniprot Q8TLP8 43
type: UnificationXref
id: Q8TLP8
db: uniprot

uniprot P9WFX9 74
type: UnificationXref
id: P9WFX9
db: uniprot

uniprot Q9FE37 47
type: UnificationXref
id: Q9FE37
db: uniprot

Anthranilate synthase beta subunit 2, chloroplastic
type: ProteinReference
xref: uniprot Q9FJM5 48
organism: Arabidopsis thaliana

Anthranilate synthase component 1
type: ProteinReference
xref: uniprot O66849 4
organism: Aquifex aeolicus

O-carboxyphenylamino 1-deoxyribuloose-5-phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot P00937 11
type: UnificationXref
id: P00937
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__indole_3_glycerol_phosphate-RIGHT__G_3_P-_indole-_r5
controller: Tryptophan synthase A

uniprot Q8AAD6 113
type: UnificationXref
id: Q8AAD6
db: uniprot

Leptospira interrogans
type: BioSource
xref: ncbitaxon 189518 38

uniprot P13228 72
type: UnificationXref
id: P13228
db: uniprot

uniprot P20170 15
type: UnificationXref
id: P20170
db: uniprot

Glr1559 protein
type: ProteinReference
xref: uniprot Q7NKB9 98
organism: Gloeobacter violaceus

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__O_carboxyphenylamino_1_deoxyribuloose_5_phosphate-RIGHT__CO2-_indole_3_glycerol_phosphate-_H2O-_r4
controller: Indole-3-glycerol phosphate synthase

Deinococcus radiodurans
type: BioSource
xref: ncbitaxon 243230 53

Anthranilate phosphoribosyltransferase
type: ProteinReference
xref: uniprot P03947 94
organism: Bacillus subtilis

uniprot Q9HSC0 85
type: UnificationXref
id: Q9HSC0
db: uniprot

Methanocaldococcus jannaschii
type: BioSource
xref: ncbitaxon 243232 30

Anthranilate phosphoribosyltransferase
type: ProteinReference
xref: uniprot O60122 90
organism: Schizosaccharomyces pombe

uniprot P00931 68
type: UnificationXref
id: P00931
db: uniprot

uniprot Q8F7V2 114
type: UnificationXref
id: Q8F7V2
db: uniprot

Indole-3-glycerol phosphate synthase
type: ProteinReference
xref: uniprot Q7NHI0 111
organism: Gloeobacter violaceus

Anthranilate synthase component 1
type: ProteinReference
xref: uniprot P03963 13
organism: Bacillus subtilis

Indole-3-glycerol phosphate synthase
type: ProteinReference
xref: uniprot P03964 109
organism: Bacillus subtilis

ncbitaxon 243274 25
type: UnificationXref
id: 243274
db: ncbitaxon

uniprot Q8TLP3 81
type: UnificationXref
id: Q8TLP3
db: uniprot

uniprot Q9RVT1 86
type: UnificationXref
id: Q9RVT1
db: uniprot

uniprot Q59992 75
type: UnificationXref
id: Q59992
db: uniprot

Arabidopsis thaliana
type: BioSource
xref: ncbitaxon 3702 28

Bifunctional protein TrpGD
type: ProteinReference
xref: uniprot Q08654 26
organism: Thermotoga maritima

Anthranilate synthase component 1
type: ProteinReference
xref: uniprot Q08653 24
organism: Thermotoga maritima

Anthranilate synthase component II
type: ProteinReference
xref: uniprot Q8F067 37
organism: Leptospira interrogans

N-(5'-phosphoribosyl)anthranilate isomerase
type: ProteinReference
xref: uniprot Q8F495 128
organism: Leptospira interrogans

ncbitaxon 83333 8
type: UnificationXref
id: 83333
db: ncbitaxon

uniprot O66849 4
type: UnificationXref
id: O66849
db: uniprot

ncbitaxon 272561 67
type: UnificationXref
id: 272561
db: ncbitaxon

ncbitaxon 226186 36
type: UnificationXref
id: 226186
db: ncbitaxon

uniprot O68814 108
type: UnificationXref
id: O68814
db: uniprot

uniprot O60122 90
type: UnificationXref
id: O60122
db: uniprot

uniprot Q8RGH8 79
type: UnificationXref
id: Q8RGH8
db: uniprot

uniprot O68608 93
type: UnificationXref
id: O68608
db: uniprot

Mycobacterium tuberculosis
type: BioSource
xref: ncbitaxon 83332 23

uniprot Q08654 26
type: UnificationXref
id: Q08654
db: uniprot

Serine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r6 146
type: Stoichiometry
physical entity: H2O
stoichiometric coefficient: 1.0

uniprot Q8ZV44 82
type: UnificationXref
id: Q8ZV44
db: uniprot

PARTICIPANT STOICHIOMETRY r6 145
type: Stoichiometry
physical entity: tryptophan
stoichiometric coefficient: 1.0

Anthranilate synthase component 1 1
type: ProteinReference
xref: uniprot Q9HPG5 49
organism: Halobacterium salinarum

PARTICIPANT STOICHIOMETRY r6 144
type: Stoichiometry
physical entity: indole
stoichiometric coefficient: 1.0

Anthranilate phosphoribosyltransferase
type: ProteinReference
xref: uniprot Q9RTJ5 104
organism: Deinococcus radiodurans

PARTICIPANT STOICHIOMETRY r6 143
type: Stoichiometry
physical entity: Serine
stoichiometric coefficient: 1.0

Anthranilate synthase component II
type: ProteinReference
xref: uniprot Q9RTJ6 52
organism: Deinococcus radiodurans

Anthranilate synthase component II
type: ProteinReference
xref: uniprot O66825 2
organism: Aquifex aeolicus

uniprot P9WFX3 22
type: UnificationXref
id: P9WFX3
db: uniprot

Escherichia coli
type: BioSource
xref: ncbitaxon 83333 8

N-(5'-phosphoribosyl)anthranilate isomerase
type: ProteinReference
xref: uniprot Q7NML1 125
organism: Gloeobacter violaceus

uniprot O66825 2
type: UnificationXref
id: O66825
db: uniprot

Anthranilate phosphoribosyltransferase, chloroplastic
type: ProteinReference
xref: uniprot Q02166 96
organism: Arabidopsis thaliana

STATE_TRANSITION_LEFT__indole_3_glycerol_phosphate-RIGHT__G_3_P-_indole-_r5
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 148
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 149
participant stoichiometry: PARTICIPANT STOICHIOMETRY r5 147
left: indole-3-glycerol phosphate
interaction type: STATE_TRANSITION
right: indole
right: G-3-P

uniprot Q9FFW8 84
type: UnificationXref
id: Q9FFW8
db: uniprot

PARTICIPANT STOICHIOMETRY r3 133
type: Stoichiometry
physical entity: O-carboxyphenylamino 1-deoxyribuloose-5-phosphate
stoichiometric coefficient: 1.0

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__2_aminobenzoate-_PRPP-RIGHT__PPi-_5_phosphoribosyl_anthranilate-_r2
controller: Anthranilate phosphoribosyl transferase

PARTICIPANT STOICHIOMETRY r3 132
type: Stoichiometry
physical entity: 5-phosphoribosyl anthranilate
stoichiometric coefficient: 1.0

ncbitaxon 188937 42
type: UnificationXref
id: 188937
db: ncbitaxon

uniprot A8IFZ9 60
type: UnificationXref
id: A8IFZ9
db: uniprot

Tryptophan synthase beta chain 1
type: ProteinReference
xref: uniprot Q9YGB0 88
organism: Thermococcus kodakaraensis

uniprot Q8TLP2 115
type: UnificationXref
id: Q8TLP2
db: uniprot

Tryptophan synthase beta chain 2
type: ProteinReference
xref: uniprot Q9WZ09 87
organism: Thermotoga maritima

uniprot P0A879 71
type: UnificationXref
id: P0A879
db: uniprot

ncbitaxon 189518 38
type: UnificationXref
id: 189518
db: ncbitaxon

Putative glutamine amidotransferase
type: ProteinReference
xref: uniprot Q9XA13 105
organism: Streptomyces coelicolor

uniprot Q56320 124
type: UnificationXref
id: Q56320
db: uniprot

uniprot Q7NM84 31
type: UnificationXref
id: Q7NM84
db: uniprot

uniprot Q42565 27
type: UnificationXref
id: Q42565
db: uniprot

Tryptophan synthase beta chain 1
type: ProteinReference
xref: uniprot O66923 64
organism: Aquifex aeolicus

uniprot Q8TLP7 41
type: UnificationXref
id: Q8TLP7
db: uniprot

uniprot Q9Z4W8 59
type: UnificationXref
id: Q9Z4W8
db: uniprot

Anthranilate synthase component 1
type: ProteinReference
xref: uniprot P20170 15
organism: Synechocystis

uniprot O67657 107
type: UnificationXref
id: O67657
db: uniprot

Bacillus subtilis
type: BioSource
xref: ncbitaxon 224308 14

Fusobacterium nucleatum
type: BioSource
xref: ncbitaxon 190304 40

uniprot Q60179 78
type: UnificationXref
id: Q60179
db: uniprot

5-phosphoribosyl anthranilate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q9XA13 105
type: UnificationXref
id: Q9XA13
db: uniprot

Multifunctional tryptophan biosynthesis protein
type: ProteinReference
xref: uniprot Q92370 46
organism: Schizosaccharomyces pombe

Tryptophan synthase beta chain 2
type: ProteinReference
xref: uniprot O67409 65
organism: Aquifex aeolicus

Anthranilate synthase
type: ProteinReference
xref: P03206
comment: ENTITY_REFERENCE_NOTES= Long Name: Anthranilate synthase Synonym: Synonym not specified Accession: P03206
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Tryptophan biosynthesis.PROTEIN.GENERIC.Anthranilate_br_synthase
member entity reference: Anthranilate synthase component II
member entity reference: Anthranilate synthase beta subunit 2, chloroplastic
member entity reference: Multifunctional tryptophan biosynthesis protein
member entity reference: Anthranilate synthase component 1
member entity reference: Para-aminobenzoate synthase component I
member entity reference: Bifunctional protein TrpGD
member entity reference: Anthranilate synthase component I-like protein
member entity reference: Probable anthranilate synthase component II
member entity reference: Aminodeoxychorismate synthase component 1
member entity reference: Anthranilate synthase beta subunit 1, chloroplastic
member entity reference: Anthranilate synthase component 1 1
member entity reference: Anthranilate synthase beta subunit
member entity reference: Anthranilate synthase component I
member entity reference: Aminodeoxychorismate synthase component 2
member entity reference: Probable anthranilate synthase component 1
member entity reference: Anthranilate synthase, component II
member entity reference: Aminodeoxychorismate/anthranilate synthase component 2

uniprot O67853 119
type: UnificationXref
id: O67853
db: uniprot

Tryptophan synthase beta chain
type: ProteinReference
xref: uniprot Q8RGH8 79
organism: Fusobacterium nucleatum

Tryptophan synthase
type: ProteinReference
xref: uniprot P13228 72
organism: Neurospora crassa

Tryptophan synthase beta chain
type: ProteinReference
xref: uniprot P07600 70
organism: Bacillus subtilis

uniprot Q9FJM5 48
type: UnificationXref
id: Q9FJM5
db: uniprot

Tryptophan biosynthesis
type: Pathway
pathway component: STATE_TRANSITION_LEFT__5_phosphoribosyl_anthranilate-RIGHT__O_carboxyphenylamino_1_deoxyribuloose_5_phosphate-_r3
pathway component: STATE_TRANSITION_LEFT__Serine-_indole-RIGHT__tryptophan-_H2O-_r6
pathway component: STATE_TRANSITION_LEFT__2_aminobenzoate-_PRPP-RIGHT__PPi-_5_phosphoribosyl_anthranilate-_r2
pathway component: STATE_TRANSITION_LEFT__O_carboxyphenylamino_1_deoxyribuloose_5_phosphate-RIGHT__CO2-_indole_3_glycerol_phosphate-_H2O-_r4
pathway component: STATE_TRANSITION_LEFT__chorismate-_glutamine-RIGHT__2_aminobenzoate-_glutamate-_pyruvate-_r1
pathway component: STATE_TRANSITION_LEFT__indole_3_glycerol_phosphate-RIGHT__G_3_P-_indole-_r5
xref: PANTHER Pathway P02783 1
comment: MODEL_NOTES= The biosynthesis of the aromatic amino acid tryptophan critical for protein biosynthesis. Website=www.biocyc.org/Ecoli/Pathways/ free text=Biochemistry (text) Voet and Voet

STATE_TRANSITION_LEFT__O_carboxyphenylamino_1_deoxyribuloose_5_phosphate-RIGHT__CO2-_indole_3_glycerol_phosphate-_H2O-_r4
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 151
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 150
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 153
participant stoichiometry: PARTICIPANT STOICHIOMETRY r4 152
left: O-carboxyphenylamino 1-deoxyribuloose-5-phosphate
interaction type: STATE_TRANSITION
right: H2O
right: indole-3-glycerol phosphate
right: CO2

Anthranilate synthase component 1
type: ProteinReference
xref: uniprot Q9YGB3 56
organism: Thermococcus kodakaraensis

CO2
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot O66585 92
type: UnificationXref
id: O66585
db: uniprot

uniprot Q8ZV46 44
type: UnificationXref
id: Q8ZV46
db: uniprot

Anthranilate synthase component 1
type: ProteinReference
xref: uniprot P9WFX3 22
organism: Mycobacterium tuberculosis

Anthranilate synthase component 1
type: ProteinReference
xref: uniprot Q58475 29
organism: Methanocaldococcus jannaschii

Methanosarcina acetivorans
type: BioSource
xref: ncbitaxon 188937 42

uniprot Q9Z4W7 58
type: UnificationXref
id: Q9Z4W7
db: uniprot

uniprot Q8TLP6 130
type: UnificationXref
id: Q8TLP6
db: uniprot

Tryptophan synthase beta chain
type: ProteinReference
xref: uniprot P07345 69
organism: Pseudomonas aeruginosa

ncbitaxon 243230 53
type: UnificationXref
id: 243230
db: ncbitaxon

uniprot Q02166 96
type: UnificationXref
id: Q02166
db: uniprot

uniprot Q5AZP9 76
type: UnificationXref
id: Q5AZP9
db: uniprot

Indole-3-glycerol phosphate synthase
type: ProteinReference
xref: uniprot Q8F7V2 114
organism: Leptospira interrogans

PPi
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Tryptophan synthase beta chain
type: ProteinReference
xref: uniprot P9WFX9 74
organism: Mycobacterium tuberculosis

uniprot Q7UMC3 126
type: UnificationXref
id: Q7UMC3
db: uniprot

uniprot Q7UYS5 100
type: UnificationXref
id: Q7UYS5
db: uniprot

Aquifex aeolicus
type: BioSource
xref: ncbitaxon 224324 3

Anthranilate synthase component 1
type: ProteinReference
xref: uniprot P20580 17
organism: Pseudomonas aeruginosa

uniprot Q9LUB2 116
type: UnificationXref
id: Q9LUB2
db: uniprot

Para-aminobenzoate synthase component I
type: ProteinReference
xref: uniprot Q9I2Y1 51
organism: Pseudomonas aeruginosa

uniprot P03947 94
type: UnificationXref
id: P03947
db: uniprot

tryptophan
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Tryptophan synthase beta chain
type: ProteinReference
xref: uniprot Q9HSC0 85
organism: Halobacterium salinarum

Anthranilate synthase component I-like protein
type: ProteinReference
xref: uniprot P74130 21
organism: Synechocystis

uniprot Q7NKB9 98
type: UnificationXref
id: Q7NKB9
db: uniprot

N-(5'-phosphoribosyl)anthranilate isomerase
type: ProteinReference
xref: uniprot Q56320 124
organism: Thermotoga maritima

Indole-3-glycerol phosphate synthase
type: ProteinReference
xref: uniprot Q56319 110
organism: Thermotoga maritima

uniprot P07345 69
type: UnificationXref
id: P07345
db: uniprot

ncbitaxon 69014 57
type: UnificationXref
id: 69014
db: ncbitaxon

Tryptophan synthase beta chain 2
type: ProteinReference
xref: uniprot Q8TL44 80
organism: Methanosarcina acetivorans

Indole-3-glycerol phosphate synthase
type: ProteinReference
xref: uniprot Q9RUG0 117
organism: Deinococcus radiodurans

Indole-3-glycerol phosphate synthase
type: Protein
entity reference: Indole-3-glycerol phosphate synthase
comment: SPECIES_TYPE=PROTEIN

2-aminobenzoate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Anthranilate phosphoribosyltransferase
type: ProteinReference
xref: uniprot O66576 91
organism: Aquifex aeolicus

Pyrobaculum aerophilum
type: BioSource
xref: ncbitaxon 178306 45

H2O
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Tryptophan synthase beta chain
type: ProteinReference
xref: uniprot O84172 66
organism: Chlamydia trachomatis

uniprot Q7UTD9 33
type: UnificationXref
id: Q7UTD9
db: uniprot

uniprot Q8F067 37
type: UnificationXref
id: Q8F067
db: uniprot

ncbitaxon 224308 14
type: UnificationXref
id: 224308
db: ncbitaxon

pyruvate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PANTHER Pathway P02783 1
type: UnificationXref
id: P02783
db: PANTHER Pathway

Rhodopirellula baltica
type: BioSource
xref: ncbitaxon 243090 34

Anthranilate phosphoribosyltransferase 1
type: ProteinReference
xref: uniprot O68608 93
organism: Streptomyces coelicolor

Streptomyces coelicolor
type: BioSource
xref: ncbitaxon 100226 55

glutamine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r4 150
type: Stoichiometry
physical entity: O-carboxyphenylamino 1-deoxyribuloose-5-phosphate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r4 151
type: Stoichiometry
physical entity: CO2
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r4 152
type: Stoichiometry
physical entity: indole-3-glycerol phosphate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r4 153
type: Stoichiometry
physical entity: H2O
stoichiometric coefficient: 1.0

ncbitaxon 243090 34
type: UnificationXref
id: 243090
db: ncbitaxon

N-(5'-phosphoribosyl)anthranilate isomerase
type: ProteinReference
xref: uniprot P00912 121
organism: Saccharomyces cerevisiae

Uncharacterized protein aq_209
type: ProteinReference
xref: uniprot O66585 92
organism: Aquifex aeolicus

PARTICIPANT STOICHIOMETRY r1 139
type: Stoichiometry
physical entity: glutamine
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r1 138
type: Stoichiometry
physical entity: chorismate
stoichiometric coefficient: 1.0

STATE_TRANSITION
type: RelationshipTypeVocabulary

STATE_TRANSITION
type: InteractionVocabulary

uniprot Q9RUG0 117
type: UnificationXref
id: Q9RUG0
db: uniprot

Indole-3-glycerol phosphate synthase
type: ProteinReference
xref: uniprot O67657 107
organism: Aquifex aeolicus

Anthranilate synthase
type: Protein
entity reference: Anthranilate synthase
comment: SPECIES_TYPE=PROTEIN

uniprot Q56319 110
type: UnificationXref
id: Q56319
db: uniprot

ncbitaxon 178306 45
type: UnificationXref
id: 178306
db: ncbitaxon

Chlamydomonas reinhardtii
type: BioSource
xref: ncbitaxon 3055 61

PARTICIPANT STOICHIOMETRY r1 141
type: Stoichiometry
physical entity: glutamate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r1 140
type: Stoichiometry
physical entity: 2-aminobenzoate
stoichiometric coefficient: 1.0

Anthranilate synthase, component II
type: ProteinReference
xref: uniprot Q8TLP8 43
organism: Methanosarcina acetivorans

uniprot Q8AAD5 101
type: UnificationXref
id: Q8AAD5
db: uniprot

ncbitaxon 100226 55
type: UnificationXref
id: 100226
db: ncbitaxon

uniprot P50909 73
type: UnificationXref
id: P50909
db: uniprot

Anthranilate synthase component I
type: ProteinReference
xref: uniprot Q8ZV46 44
organism: Pyrobaculum aerophilum

Tryptophan synthase beta chain
type: ProteinReference
xref: uniprot P0A879 71
organism: Escherichia coli

Tryptophan synthase beta chain
type: ProteinReference
xref: uniprot Q8ZV44 82
organism: Pyrobaculum aerophilum

Anthranilate phosphoribosyltransferase
type: ProteinReference
xref: uniprot F4I5H7 89
organism: Arabidopsis thaliana

Tryptophan synthase beta chain
type: ProteinReference
xref: uniprot Q59992 75
organism: Synechocystis

uniprot Q9YGB0 88
type: UnificationXref
id: Q9YGB0
db: uniprot

N-(5'-phosphoribosyl)anthranilate isomerase
type: ProteinReference
xref: uniprot Q9RY28 131
organism: Deinococcus radiodurans

Indole-3-glycerol phosphate synthase 2
type: ProteinReference
xref: uniprot Q9Z4X0 118
organism: Streptomyces coelicolor

uniprot Q42527 123
type: UnificationXref
id: Q42527
db: uniprot

Tryptophan synthase B
type: Protein
entity reference: Tryptophan synthase B
comment: SPECIES_TYPE=PROTEIN

STATE_TRANSITION_LEFT__Serine-_indole-RIGHT__tryptophan-_H2O-_r6
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 145
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 146
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 143
participant stoichiometry: PARTICIPANT STOICHIOMETRY r6 144
left: Serine
left: indole
interaction type: STATE_TRANSITION
right: H2O
right: tryptophan

uniprot P28820 20
type: UnificationXref
id: P28820
db: uniprot

ncbitaxon 3055 61
type: UnificationXref
id: 3055
db: ncbitaxon

Aminodeoxychorismate synthase component 2
type: ProteinReference
xref: uniprot P00903 7
organism: Escherichia coli

Multifunctional tryptophan biosynthesis protein
type: ProteinReference
xref: uniprot P00908 9
organism: Neurospora crassa

N-(5'-phosphoribosyl)anthranilate isomerase 1, chloroplastic
type: ProteinReference
xref: uniprot Q42440 122
organism: Arabidopsis thaliana

uniprot P00908 9
type: UnificationXref
id: P00908
db: uniprot

PARTICIPANT STOICHIOMETRY r1 142
type: Stoichiometry
physical entity: pyruvate
stoichiometric coefficient: 1.0

uniprot O05625 62
type: UnificationXref
id: O05625
db: uniprot

N-(5'-phosphoribosyl)anthranilate isomerase 2, chloroplastic
type: ProteinReference
xref: uniprot Q42527 123
organism: Arabidopsis thaliana

Indole-3-glycerol phosphate synthase 1
type: ProteinReference
xref: uniprot O68814 108
organism: Streptomyces coelicolor

Anthranilate synthase component II
type: ProteinReference
xref: uniprot Q8RI82 39
organism: Fusobacterium nucleatum

Tryptophan synthase A
type: Protein
comment: SPECIES_TYPE=PROTEIN

uniprot O84172 66
type: UnificationXref
id: O84172
db: uniprot

uniprot P07285 95
type: UnificationXref
id: P07285
db: uniprot

Indole-3-glycerol phosphate synthase
type: ProteinReference
xref: uniprot Q7UKJ7 112
organism: Rhodopirellula baltica

uniprot Q8TLP5 103
type: UnificationXref
id: Q8TLP5
db: uniprot

N-(5'-phosphoribosyl)anthranilate isomerase
type: ProteinReference
xref: uniprot O67853 119
organism: Aquifex aeolicus

indole
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Multifunctional tryptophan biosynthesis protein
type: ProteinReference
xref: uniprot P00937 11
organism: Saccharomyces cerevisiae

Tryptophan synthase
type: ProteinReference
xref: uniprot P00931 68
organism: Saccharomyces cerevisiae

N-(5'-phosphoribosyl)anthranilate isomerase
type: ProteinReference
xref: uniprot Q8TLP6 130
organism: Methanosarcina acetivorans

Probable anthranilate synthase component II
type: ProteinReference
xref: uniprot Q9Z4W8 59
organism: Streptomyces coelicolor

Anthranilate phosphoribosyltransferase 2
type: ProteinReference
xref: uniprot Q9Z4W9 106
organism: Streptomyces coelicolor

Anthranilate synthase component 1
type: ProteinReference
xref: uniprot Q8TLP7 41
organism: Methanosarcina acetivorans

Anthranilate phosphoribosyltransferase
type: ProteinReference
xref: uniprot Q8TLP5 103
organism: Methanosarcina acetivorans

Indole-3-glycerol phosphate synthase
type: ProteinReference
xref: uniprot Q8TLP2 115
organism: Methanosarcina acetivorans

Probable anthranilate synthase component 1
type: ProteinReference
xref: uniprot O94582 5
organism: Schizosaccharomyces pombe

Tryptophan synthase beta chain 1
type: ProteinReference
xref: uniprot Q8TLP3 81
organism: Methanosarcina acetivorans

uniprot O84331 120
type: UnificationXref
id: O84331
db: uniprot

uniprot Q9Z4X0 118
type: UnificationXref
id: Q9Z4X0
db: uniprot

Anthranilate phosphoribosyl transferase
type: ProteinReference
xref: P03209
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: Anthranilate phosphoribosyl transferase Synonym: Synonym not specified Accession: P03209
comment: ENTITY_REFERENCE_ID_DESC=Tryptophan biosynthesis.PROTEIN.GENERIC.Anthranilate_br_phosphoribosyl_br_transferase
member entity reference: Anthranilate synthase component II
member entity reference: Anthranilate synthase beta subunit 2, chloroplastic
member entity reference: Multifunctional tryptophan biosynthesis protein
member entity reference: Anthranilate phosphoribosyltransferase, chloroplastic
member entity reference: Anthranilate phosphoribosyltransferase 1
member entity reference: Anthranilate phosphoribosyltransferase
member entity reference: Bifunctional protein TrpGD
member entity reference: Probable anthranilate synthase component II
member entity reference: Anthranilate synthase beta subunit 1, chloroplastic
member entity reference: Anthranilate synthase beta subunit
member entity reference: Aminodeoxychorismate synthase component 2
member entity reference: Anthranilate synthase, component II
member entity reference: Aminodeoxychorismate/anthranilate synthase component 2
member entity reference: Glr1559 protein
member entity reference: Anthranilate phosphoribosyltransferase 2
member entity reference: Putative glutamine amidotransferase
member entity reference: Uncharacterized protein aq_209

Anthranilate synthase component 1
type: ProteinReference
xref: uniprot Q9Z4W7 58
organism: Streptomyces coelicolor

Tryptophan synthase
type: ProteinReference
xref: uniprot Q5AZP9 76
organism: Emericella nidulans

Tryptophan synthase beta chain
type: ProteinReference
xref: uniprot Q9FFW8 84
organism: Arabidopsis thaliana

uniprot Q9WZ09 87
type: UnificationXref
id: Q9WZ09
db: uniprot

uniprot Q8TL44 80
type: UnificationXref
id: Q8TL44
db: uniprot

uniprot Q8F708 102
type: UnificationXref
id: Q8F708
db: uniprot

Tryptophan synthase
type: ProteinReference
xref: uniprot O13831 63
organism: Schizosaccharomyces pombe

Emericella nidulans
type: BioSource
xref: ncbitaxon 227321 77

Pseudomonas aeruginosa
type: BioSource
xref: ncbitaxon 208964 18

uniprot Q8F495 128
type: UnificationXref
id: Q8F495
db: uniprot

uniprot Q9RTJ6 52
type: UnificationXref
id: Q9RTJ6
db: uniprot

ncbitaxon 251221 32
type: UnificationXref
id: 251221
db: ncbitaxon

ncbitaxon 284812 6
type: UnificationXref
id: 284812
db: ncbitaxon

uniprot Q9S2U2 54
type: UnificationXref
id: Q9S2U2
db: uniprot

ncbitaxon 190304 40
type: UnificationXref
id: 190304
db: ncbitaxon