uniprot Q9S7H4 19
type: UnificationXref
id: Q9S7H4
db: uniprot

Chorismate mutase
type: ProteinReference
xref: uniprot Q7S8R4 12
organism: Neurospora crassa

Aromatic amino acid aminotransferase
type: Protein
comment: SPECIES_TYPE=PROTEIN

Prephenate dehydrogenase
type: ProteinReference
xref: uniprot P20692 22
organism: Bacillus subtilis

chorismate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Gloeobacter violaceus
type: BioSource
xref: ncbitaxon 251221 11

Chorismate mutase
type: Protein
entity reference: Chorismate mutase
comment: SPECIES_TYPE=PROTEIN

Bacillus subtilis
type: BioSource
xref: ncbitaxon 224308 5

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__chorismate-RIGHT__prephenate-_r1
controller: Chorismate mutase

Prephenate dehydrogenase
type: ProteinReference
xref: uniprot Q9WYH9 30
organism: Thermotoga maritima

Thermotoga maritima
type: BioSource
xref: ncbitaxon 243274 31

PARTICIPANT STOICHIOMETRY r3 33
type: Stoichiometry
physical entity: glutamate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r3 34
type: Stoichiometry
physical entity: P-hydroxyphenylpyruvate
stoichiometric coefficient: 1.0

ncbitaxon 367110 13
type: UnificationXref
id: 367110
db: ncbitaxon

Tyrosine biosynthesis
type: Pathway
pathway component: STATE_TRANSITION_LEFT__chorismate-RIGHT__prephenate-_r1
pathway component: STATE_TRANSITION_LEFT__glutamate-_P_hydroxyphenylpyruvate-RIGHT__tyrosine-_ketoglutarate-_r3
pathway component: STATE_TRANSITION_LEFT__NAD-_prephenate-RIGHT__CO2-_NADH-_P_hydroxyphenylpyruvate-_r2
xref: PANTHER Pathway P02784 1
comment: MODEL_NOTES= Biosynthesis of the aromatic amino acid tyrosine involved in protein biosynthesis. Website=www.biocyc.org/Ecoli Website=www.biocyc.org/Ecoli/Pathways/ free text=Biochemistry (text) Voet and Voet

Bifunctional prephenate dehydrogenase/chorismate mutase
type: ProteinReference
xref: uniprot Q8F6P6 26
organism: Leptospira interrogans

uniprot Q9C544 16
type: UnificationXref
id: Q9C544
db: uniprot

Chorismate mutase
type: ProteinReference
xref: P03212
comment: ENTITY_REFERENCE_ID_DESC=Tyrosine biosynthesis.PROTEIN.GENERIC.Chorismate mutase
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: Chorismate mutase Synonym: Synonym not specified Accession: P03212
member entity reference: Chorismate mutase AroH
member entity reference: Chorismate mutase 1, chloroplastic
member entity reference: Chorismate mutase
member entity reference: Chorismate mutase 3, chloroplastic
member entity reference: Probable chorismate mutase
member entity reference: Chorismate mutase 2

Saccharomyces cerevisiae
type: BioSource
xref: ncbitaxon 559292 7

uniprot O67636 20
type: UnificationXref
id: O67636
db: uniprot

CO2
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r1 43
type: Stoichiometry
physical entity: prephenate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r3 36
type: Stoichiometry
physical entity: ketoglutarate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r1 42
type: Stoichiometry
physical entity: chorismate
stoichiometric coefficient: 1.0

P03214
type: UnificationXref
id: P03214
db: PANTHER Pathway Component

PARTICIPANT STOICHIOMETRY r3 35
type: Stoichiometry
physical entity: tyrosine
stoichiometric coefficient: 1.0

P03212
type: UnificationXref
id: P03212
db: PANTHER Pathway Component

Probable chorismate mutase
type: ProteinReference
xref: uniprot O13739 2
organism: Schizosaccharomyces pombe

ncbitaxon 243274 31
type: UnificationXref
id: 243274
db: ncbitaxon

uniprot Q8CK19 25
type: UnificationXref
id: Q8CK19
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__glutamate-_P_hydroxyphenylpyruvate-RIGHT__tyrosine-_ketoglutarate-_r3
controller: Aromatic amino acid aminotransferase

Chorismate mutase
type: ProteinReference
xref: uniprot Q9S238 17
organism: Streptomyces coelicolor

Aquifex aeolicus
type: BioSource
xref: ncbitaxon 224324 21

ncbitaxon 224324 21
type: UnificationXref
id: 224324
db: ncbitaxon

Prephenate dehydrogenase
type: ProteinReference
xref: P03214
comment: ENTITY_REFERENCE_NOTES= Long Name: Prephenate dehydrogenase Synonym: Synonym not specified Accession: P03214
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Tyrosine biosynthesis.PROTEIN.GENERIC.Prephenate_br_dehydrogenase
member entity reference: Prephenate dehydrogenase
member entity reference: Putative cyclohexadienyl dehydrogenase
member entity reference: Bifunctional prephenate dehydrogenase/chorismate mutase
member entity reference: Putative oxidoreductase

Neurospora crassa
type: BioSource
xref: ncbitaxon 367110 13

uniprot Q7URX9 24
type: UnificationXref
id: Q7URX9
db: uniprot

NAD
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ncbitaxon 243090 15
type: UnificationXref
id: 243090
db: ncbitaxon

uniprot Q9WYH9 30
type: UnificationXref
id: Q9WYH9
db: uniprot

ncbitaxon 243230 29
type: UnificationXref
id: 243230
db: ncbitaxon

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__NAD-_prephenate-RIGHT__CO2-_NADH-_P_hydroxyphenylpyruvate-_r2
controller: Prephenate dehydrogenase

ncbitaxon 224308 5
type: UnificationXref
id: 224308
db: ncbitaxon

tyrosine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ncbitaxon 559292 7
type: UnificationXref
id: 559292
db: ncbitaxon

uniprot P32178 6
type: UnificationXref
id: P32178
db: uniprot

Schizosaccharomyces pombe
type: BioSource
xref: ncbitaxon 284812 3

Prephenate dehydrogenase
type: ProteinReference
xref: uniprot Q9RVA7 28
organism: Deinococcus radiodurans

Chorismate mutase
type: ProteinReference
xref: uniprot Q7UMM1 14
organism: Rhodopirellula baltica

Rhodopirellula baltica
type: BioSource
xref: ncbitaxon 243090 15

STATE_TRANSITION_LEFT__chorismate-RIGHT__prephenate-_r1
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 43
participant stoichiometry: PARTICIPANT STOICHIOMETRY r1 42
left: chorismate
interaction type: STATE_TRANSITION
right: prephenate

Streptomyces coelicolor
type: BioSource
xref: ncbitaxon 100226 18

ncbitaxon 251221 11
type: UnificationXref
id: 251221
db: ncbitaxon

Chorismate mutase AroH
type: ProteinReference
xref: uniprot P19080 4
organism: Bacillus subtilis

uniprot P42738 8
type: UnificationXref
id: P42738
db: uniprot

STATE_TRANSITION_LEFT__NAD-_prephenate-RIGHT__CO2-_NADH-_P_hydroxyphenylpyruvate-_r2
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 38
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 40
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 39
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 37
participant stoichiometry: PARTICIPANT STOICHIOMETRY r2 41
left: prephenate
left: NAD
interaction type: STATE_TRANSITION
right: CO2
right: P-hydroxyphenylpyruvate
right: NADH

uniprot Q7S8R4 12
type: UnificationXref
id: Q7S8R4
db: uniprot

prephenate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q8F6P6 26
type: UnificationXref
id: Q8F6P6
db: uniprot

STATE_TRANSITION
type: InteractionVocabulary

STATE_TRANSITION
type: RelationshipTypeVocabulary

ncbitaxon 189518 27
type: UnificationXref
id: 189518
db: ncbitaxon

ncbitaxon 284812 3
type: UnificationXref
id: 284812
db: ncbitaxon

Prephenate dehydrogenase
type: ProteinReference
xref: uniprot Q7NNK5 23
organism: Gloeobacter violaceus

uniprot P19080 4
type: UnificationXref
id: P19080
db: uniprot

PANTHER Pathway P02784 1
type: UnificationXref
id: P02784
db: PANTHER Pathway

Chorismate mutase 1, chloroplastic
type: ProteinReference
xref: uniprot P42738 8
organism: Arabidopsis thaliana

Leptospira interrogans
type: BioSource
xref: ncbitaxon 189518 27

Deinococcus radiodurans
type: BioSource
xref: ncbitaxon 243230 29

Chorismate mutase 3, chloroplastic
type: ProteinReference
xref: uniprot Q9C544 16
organism: Arabidopsis thaliana

Chorismate mutase 2
type: ProteinReference
xref: uniprot Q9S7H4 19
organism: Arabidopsis thaliana

Putative cyclohexadienyl dehydrogenase
type: ProteinReference
xref: uniprot Q8CK19 25
organism: Streptomyces coelicolor

Chorismate mutase AroH
type: ProteinReference
xref: uniprot Q7NH32 10
organism: Gloeobacter violaceus

Chorismate mutase
type: ProteinReference
xref: uniprot P32178 6
organism: Saccharomyces cerevisiae

STATE_TRANSITION_LEFT__glutamate-_P_hydroxyphenylpyruvate-RIGHT__tyrosine-_ketoglutarate-_r3
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 35
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 36
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 34
participant stoichiometry: PARTICIPANT STOICHIOMETRY r3 33
left: glutamate
left: P-hydroxyphenylpyruvate
interaction type: STATE_TRANSITION
right: ketoglutarate
right: tyrosine

uniprot Q7UMM1 14
type: UnificationXref
id: Q7UMM1
db: uniprot

Arabidopsis thaliana
type: BioSource
xref: ncbitaxon 3702 9

uniprot Q7NH32 10
type: UnificationXref
id: Q7NH32
db: uniprot

Putative oxidoreductase
type: ProteinReference
xref: uniprot Q9Z4W3 32
organism: Streptomyces coelicolor

uniprot P20692 22
type: UnificationXref
id: P20692
db: uniprot

Prephenate dehydrogenase
type: Protein
entity reference: Prephenate dehydrogenase
comment: SPECIES_TYPE=PROTEIN

ketoglutarate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Prephenate dehydrogenase
type: ProteinReference
xref: uniprot O67636 20
organism: Aquifex aeolicus

P-hydroxyphenylpyruvate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ncbitaxon 3702 9
type: UnificationXref
id: 3702
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r2 38
type: Stoichiometry
physical entity: prephenate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r2 39
type: Stoichiometry
physical entity: CO2
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r2 37
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

uniprot O13739 2
type: UnificationXref
id: O13739
db: uniprot

uniprot Q9RVA7 28
type: UnificationXref
id: Q9RVA7
db: uniprot

uniprot Q9Z4W3 32
type: UnificationXref
id: Q9Z4W3
db: uniprot

glutamate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q9S238 17
type: UnificationXref
id: Q9S238
db: uniprot

uniprot Q7NNK5 23
type: UnificationXref
id: Q7NNK5
db: uniprot

PARTICIPANT STOICHIOMETRY r2 41
type: Stoichiometry
physical entity: P-hydroxyphenylpyruvate
stoichiometric coefficient: 1.0

NADH
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ncbitaxon 100226 18
type: UnificationXref
id: 100226
db: ncbitaxon

Prephenate dehydrogenase
type: ProteinReference
xref: uniprot Q7URX9 24
organism: Rhodopirellula baltica

PARTICIPANT STOICHIOMETRY r2 40
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0