Pyridoxamine phosphate transaminase
type: Protein
comment: SPECIES_TYPE=PROTEIN

D-Alanine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Pyridoxal_5_phosphate-RIGHT__Pyridoxal-_r124
controller: Pyridoxal kinase

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Pyridoxine_phosphate-RIGHT__Pyridoxine-_r126
controller: Pyridoxal kinase

ncbitaxon 10116 3
type: UnificationXref
id: 10116
db: ncbitaxon

Pyridoxamine 5'-phosphate oxidase
type: ProteinReference
xref: PTHR10851:SF0
xref: uniprot E2QTE2 24
organism: Canis lupus familiaris

STATE_TRANSITION_LEFT__Pyridoxine_phosphate-RIGHT__Pyridoxal_5_phosphate-_r112
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r112 114
participant stoichiometry: PARTICIPANT STOICHIOMETRY r112 113
left: Pyridoxine phosphate
interaction type: STATE_TRANSITION
right: Pyridoxal 5-phosphate

Pyridoxal kinase
type: ProteinReference
xref: uniprot Q0II59 75
xref: PTHR10534:SF2
organism: Bos taurus

Pyridoxal kinase
type: ProteinReference
xref: uniprot O00764 69
xref: PTHR10534:SF2
organism: Homo sapiens

Threonine synthase
type: ProteinReference
xref: PTHR10314:SF5
xref: uniprot O66740 48
organism: Aquifex aeolicus

PTHR10534:SF2
type: RelationshipXref
id: PTHR10534:SF2
db: PANTHER Family
relationship type: By Homology

Pyridoxal kinase
type: ProteinReference
xref: uniprot Q8K183 78
xref: PTHR10534:SF2
organism: Mus musculus

uniprot P40191 73
type: UnificationXref
id: P40191
db: uniprot

Probable pyridoxamine 5'-phosphate oxidase
type: ProteinReference
xref: PTHR10851:SF0
xref: uniprot Q9UTQ1 45
organism: Schizosaccharomyces pombe

PARTICIPANT STOICHIOMETRY r131 157
type: Stoichiometry
physical entity: Pyridoxine
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r131 158
type: Stoichiometry
physical entity: Isopyridoxal
stoichiometric coefficient: 1.0

uniprot P29363 53
type: UnificationXref
id: P29363
db: uniprot

Cryptococcus neoformans
type: BioSource
xref: ncbitaxon 214684 62

ncbitaxon 9615 25
type: UnificationXref
id: 9615
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r125 90
type: Stoichiometry
physical entity: Pyridoxine phosphate
stoichiometric coefficient: 1.0

PTHR10314:SF5
type: RelationshipXref
id: PTHR10314:SF5
db: PANTHER Family
relationship type: By Homology

Threonine synthase
type: ProteinReference
xref: uniprot Q42598 58
xref: PTHR42690:SF1
organism: Schizosaccharomyces pombe

ncbitaxon 224308 16
type: UnificationXref
id: 224308
db: ncbitaxon

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Pyridoxamine-RIGHT__Pyridoxal-_r110
controller: Pyridoxamine phosphate transaminase

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__2__Acetamidomethylene__succinate-RIGHT__Succinate_semialdehyde-_r87
controller: 2-(Acetamidomethylene) succinate hydrolase

Pyridoxal kinase
type: ProteinReference
xref: uniprot Q55EK9 76
xref: PTHR10534:SF2
organism: Dictyostelium discoideum

3-Hydroxy-2 methylpyridine-4,5-dicarboxylate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Phosphoserine aminotransferase
type: ProteinReference
xref: PTHR43247:SF1
xref: uniprot A0A0G2K931 2
organism: Rattus norvegicus

ncbitaxon 44689 77
type: UnificationXref
id: 44689
db: ncbitaxon

STATE_TRANSITION_LEFT__Pyridoxamine-RIGHT__Pyridoxamine_5_phosphate-_r127
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r127 85
participant stoichiometry: PARTICIPANT STOICHIOMETRY r127 86
left: Pyridoxamine
interaction type: STATE_TRANSITION
right: Pyridoxamine 5-phosphate

Mus musculus
type: BioSource
xref: ncbitaxon 10090 20

Phosphoserine aminotransferase
type: ProteinReference
xref: uniprot P23721 11
xref: PTHR43247:SF1
organism: Escherichia coli

STATE_TRANSITION_LEFT__Pyridoxal_5_phosphate-RIGHT__Pyridoxal-_r124
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r124 91
participant stoichiometry: PARTICIPANT STOICHIOMETRY r124 92
left: Pyridoxal 5-phosphate
interaction type: STATE_TRANSITION
right: Pyridoxal

Pyridoxine-5'-phosphate oxidase
type: ProteinReference
xref: PTHR10851:SF0
xref: uniprot A0A1D5Q928 23
organism: Macaca mulatta

Pyridoxal
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r125 89
type: Stoichiometry
physical entity: Pyridoxine
stoichiometric coefficient: 1.0

STATE_TRANSITION_LEFT__3_Amino_2_oxopropyl_phosphate-RIGHT__Pyridoxine_phosphate-_r148
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r148 106
participant stoichiometry: PARTICIPANT STOICHIOMETRY r148 105
left: 3-Amino-2-oxopropyl phosphate
interaction type: STATE_TRANSITION
right: Pyridoxine phosphate

Pyridoxine phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot F7H2J8 9
type: UnificationXref
id: F7H2J8
db: uniprot

uniprot P00934 51
type: UnificationXref
id: P00934
db: uniprot

Pyridoxine-5'-phosphate oxidase
type: ProteinReference
xref: PTHR10851:SF0
xref: uniprot Q91XF0 36
organism: Mus musculus

PARTICIPANT STOICHIOMETRY r122 96
type: Stoichiometry
physical entity: Pyridoxal
stoichiometric coefficient: 1.0

Saccharomyces cerevisiae
type: BioSource
xref: ncbitaxon 559292 14

Synechocystis
type: BioSource
xref: ncbitaxon 1111708 32

uniprot P80862 15
type: UnificationXref
id: P80862
db: uniprot

uniprot Q58860 59
type: UnificationXref
id: Q58860
db: uniprot

KNOWN_TRANSITION_OMITTED_LEFT__5_Pyridoxolactone-RIGHT__3_Hydroxy_4_hydroxymethyl_2_methylpyridine_5_carboxylate-_r137
type: Conversion
conversion direction: LEFT_TO_RIGHT
xref: KNOWN TRANSITION OMITTED
participant stoichiometry: PARTICIPANT STOICHIOMETRY r137 146
participant stoichiometry: PARTICIPANT STOICHIOMETRY r137 145
left: 5-Pyridoxolactone
interaction type: KNOWN_TRANSITION_OMITTED
right: 3-Hydroxy-4-hydroxymethyl-2-methylpyridine 5-carboxylate

PARTICIPANT STOICHIOMETRY r148 105
type: Stoichiometry
physical entity: 3-Amino-2-oxopropyl phosphate
stoichiometric coefficient: 1.0

D-Glutamate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r121 98
type: Stoichiometry
physical entity: Pyridoxine
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r121 97
type: Stoichiometry
physical entity: Pyridoxal
stoichiometric coefficient: 1.0

ncbitaxon 284812 46
type: UnificationXref
id: 284812
db: ncbitaxon

uniprot D6XI07 66
type: UnificationXref
id: D6XI07
db: uniprot

ISS
type: EvidenceCodeVocabulary
xref: eco ECO:0000250 8

Phosphoserine aminotransferase
type: ProteinReference
xref: uniprot P33330 13
xref: PTHR43247:SF1
organism: Saccharomyces cerevisiae

PARTICIPANT STOICHIOMETRY r148 106
type: Stoichiometry
physical entity: Pyridoxine phosphate
stoichiometric coefficient: 1.0

uniprot P77150 74
type: UnificationXref
id: P77150
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__O_Phospho_4_hydroxy_L_threonine-RIGHT__2_Oxo_3_hydroxy_4_phosphobutaonate-_r144
controller: Phosphoserine transaminase

4-hydroxythreonine-4-phosphate dehydrogenase
type: Protein
comment: SPECIES_TYPE=PROTEIN

Pyridoxine 4-oxidase
type: Protein
comment: SPECIES_TYPE=PROTEIN

PARTICIPANT STOICHIOMETRY r144 116
type: Stoichiometry
physical entity: 2-Oxo-3-hydroxy 4-phosphobutaonate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r150 102
type: Stoichiometry
physical entity: 4-Phospho D-erythronate
stoichiometric coefficient: 1.0

Pyridoxine/pyridoxamine 5'-phosphate oxidase
type: ProteinReference
xref: PTHR10851:SF0
xref: uniprot Q9K3V7 39
organism: Streptomyces coelicolor

PARTICIPANT STOICHIOMETRY r144 115
type: Stoichiometry
physical entity: O-Phospho 4-hydroxy L-threonine
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r150 101
type: Stoichiometry
physical entity: D-Erythrose 4-phosphate
stoichiometric coefficient: 1.0

STATE_TRANSITION_LEFT__3_Hydroxy_2_methylpyridine_4,5_dicarboxylate-RIGHT__3_Hydroxy_2_methylpyridine_5_carboxylate-_r92
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r92 138
participant stoichiometry: PARTICIPANT STOICHIOMETRY r92 137
left: 3-Hydroxy-2 methylpyridine-4,5-dicarboxylate
interaction type: STATE_TRANSITION
right: 3-Hydroxy-2 methylpyridine-5-carboxylate

PARTICIPANT STOICHIOMETRY r124 92
type: Stoichiometry
physical entity: Pyridoxal
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r124 91
type: Stoichiometry
physical entity: Pyridoxal 5-phosphate
stoichiometric coefficient: 1.0

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__2_Oxoglutarate-_Pyridoxal_5_phosphate-_Pyruvate-RIGHT__D_Glutamate-_Pyridoxamine_5_phosphate-_D_Alanine-_r111
controller: Pyridoxamine phosphate transaminase

ncbitaxon 3702 18
type: UnificationXref
id: 3702
db: ncbitaxon

3-Hydroxy-2 methylpyridine-5-carboxylate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Pyridoxine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Pyridoxal kinase
type: ProteinReference
xref: uniprot A0A2I3T5F1 64
xref: PTHR10534:SF2
organism: Pan troglodytes

ncbitaxon 9913 7
type: UnificationXref
id: 9913
db: ncbitaxon

PTHR42690:SF1
type: RelationshipXref
id: PTHR42690:SF1
db: PANTHER Family
relationship type: By Homology

uniprot O66864 50
type: UnificationXref
id: O66864
db: uniprot

uniprot A0A2I3T5F1 64
type: UnificationXref
id: A0A2I3T5F1
db: uniprot

MODULATION
type: Control
xref: MODULATION
controlled: STATE_TRANSITION_LEFT__Pyridoxine-RIGHT__Pyridoxal-_r122
controller: Pyridoxine 4-dehydrogenase

STATE_TRANSITION_LEFT__2__Acetamidomethylene__succinate-RIGHT__Succinate_semialdehyde-_r87
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r87 154
participant stoichiometry: PARTICIPANT STOICHIOMETRY r87 153
left: 2-(Acetamidomethylene) succinate
interaction type: STATE_TRANSITION
right: Succinate semialdehyde

3-Hydroxy-4-hydroxymethyl-2-methylpyridine 5-carboxylate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Threonine synthase
type: ProteinReference
xref: PTHR10314:SF96
xref: uniprot O66864 50
organism: Aquifex aeolicus

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__3_Hydroxy_2_methylpyridine_4,5_dicarboxylate-RIGHT__3_Hydroxy_2_methylpyridine_5_carboxylate-_r92
controller: 3-Hydroxy-2-methylpyridine 4,5-dicarboxylate 4-decarboxylase

Neurospora crassa
type: BioSource
xref: ncbitaxon 367110 57

Threonine synthase
type: ProteinReference
xref: uniprot P29363 53
xref: PTHR42690:SF1
organism: Pseudomonas aeruginosa

KNOWN_TRANSITION_OMITTED_LEFT__2_Methyl_3_Hydroxy_5_formylpyridine_4_carboxylate-RIGHT__3_Hydroxy_2_methylpyridine_4,5_dicarboxylate-_r93
type: Conversion
conversion direction: LEFT_TO_RIGHT
xref: KNOWN TRANSITION OMITTED
participant stoichiometry: PARTICIPANT STOICHIOMETRY r93 135
participant stoichiometry: PARTICIPANT STOICHIOMETRY r93 136
left: 2-Methyl-3-Hydroxy-5-formylpyridine-4-carboxylate
interaction type: KNOWN_TRANSITION_OMITTED
right: 3-Hydroxy-2 methylpyridine-4,5-dicarboxylate

STATE_TRANSITION_LEFT__O_Phospho_4_hydroxy_L_threonine-RIGHT__3_Amino_2_oxopropyl_phosphate-_r147
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r147 107
participant stoichiometry: PARTICIPANT STOICHIOMETRY r147 108
left: O-Phospho 4-hydroxy L-threonine
interaction type: STATE_TRANSITION
right: 3-Amino-2-oxopropyl phosphate

STATE_TRANSITION_LEFT__Pyridoxal-RIGHT__4_Pyridoxate-_r106
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r106 142
participant stoichiometry: PARTICIPANT STOICHIOMETRY r106 141
left: Pyridoxal
interaction type: STATE_TRANSITION
right: 4-Pyridoxate

uniprot O35331 71
type: UnificationXref
id: O35331
db: uniprot

ncbitaxon 185431 67
type: UnificationXref
id: 185431
db: ncbitaxon

uniprot Q9UTQ1 45
type: UnificationXref
id: Q9UTQ1
db: uniprot

uniprot Q96255 17
type: UnificationXref
id: Q96255
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__3_Hydroxy_4_hydroxymethyl_2_methylpyridine_5_carboxylate-RIGHT__2__Acetamidomethylene__3_hydroxymethyl_succinate-_r134
controller: 5-pyridoxate dioxygenase

Schizosaccharomyces pombe
type: BioSource
xref: ncbitaxon 284812 46

Ashbya gossypii
type: BioSource
xref: ncbitaxon 284811 55

STATE_TRANSITION_LEFT__2_Oxoglutarate-_Pyridoxal_5_phosphate-_Pyruvate-RIGHT__D_Glutamate-_Pyridoxamine_5_phosphate-_D_Alanine-_r111
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r111 124
participant stoichiometry: PARTICIPANT STOICHIOMETRY r111 120
participant stoichiometry: PARTICIPANT STOICHIOMETRY r111 119
participant stoichiometry: PARTICIPANT STOICHIOMETRY r111 122
participant stoichiometry: PARTICIPANT STOICHIOMETRY r111 121
participant stoichiometry: PARTICIPANT STOICHIOMETRY r111 123
left: Pyridoxal 5-phosphate
left: 2-Oxoglutarate
left: Pyruvate
interaction type: STATE_TRANSITION
right: D-Glutamate
right: Pyridoxamine 5-phosphate
right: D-Alanine

uniprot O74860 72
type: UnificationXref
id: O74860
db: uniprot

PARTICIPANT STOICHIOMETRY r93 136
type: Stoichiometry
physical entity: 3-Hydroxy-2 methylpyridine-4,5-dicarboxylate
stoichiometric coefficient: 1.0

Threonine synthase
type: ProteinReference
xref: PTHR10314:SF5
xref: uniprot Q58860 59
organism: Methanocaldococcus jannaschii

uniprot Q9RYF8 63
type: UnificationXref
id: Q9RYF8
db: uniprot

PARTICIPANT STOICHIOMETRY r93 135
type: Stoichiometry
physical entity: 2-Methyl-3-Hydroxy-5-formylpyridine-4-carboxylate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r137 145
type: Stoichiometry
physical entity: 5-Pyridoxolactone
stoichiometric coefficient: 1.0

Pyruvate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Pan troglodytes
type: BioSource
xref: ncbitaxon 9598 27

PARTICIPANT STOICHIOMETRY r135 149
type: Stoichiometry
physical entity: 2-(Acetamidomethylene) 3-hydroxymethyl succinate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r137 146
type: Stoichiometry
physical entity: 3-Hydroxy-4-hydroxymethyl-2-methylpyridine 5-carboxylate
stoichiometric coefficient: 1.0

ncbitaxon 9544 10
type: UnificationXref
id: 9544
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r92 137
type: Stoichiometry
physical entity: 3-Hydroxy-2 methylpyridine-4,5-dicarboxylate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r92 138
type: Stoichiometry
physical entity: 3-Hydroxy-2 methylpyridine-5-carboxylate
stoichiometric coefficient: 1.0

KNOWN_TRANSITION_OMITTED_LEFT__4_Pyridoxate-RIGHT__Excretion-_r96
type: Conversion
conversion direction: LEFT_TO_RIGHT
xref: KNOWN TRANSITION OMITTED
participant stoichiometry: PARTICIPANT STOICHIOMETRY r96 132
participant stoichiometry: PARTICIPANT STOICHIOMETRY r96 131
left: 4-Pyridoxate
interaction type: KNOWN_TRANSITION_OMITTED
right: Excretion

uniprot Q5E9K3 35
type: UnificationXref
id: Q5E9K3
db: uniprot

uniprot P23721 11
type: UnificationXref
id: P23721
db: uniprot

Threonine synthase
type: ProteinReference
xref: P03242
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Vitamin B6 metabolism.PROTEIN.GENERIC.Threonine_br_synthase
comment: ENTITY_REFERENCE_NOTES= Long Name: Threonine synthase Synonym: Synonym not specified Accession: P03242
member entity reference: Threonine synthase
member entity reference: Threonine synthase, putative

PARTICIPANT STOICHIOMETRY r94 133
type: Stoichiometry
physical entity: 4-Pyridoxate
stoichiometric coefficient: 1.0

PTHR43247:SF5
type: RelationshipXref
id: PTHR43247:SF5
db: PANTHER Family
relationship type: By Homology

PARTICIPANT STOICHIOMETRY r94 134
type: Stoichiometry
physical entity: 2-Methyl-3-Hydroxy-5-formylpyridine-4-carboxylate
stoichiometric coefficient: 1.0

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Pyridoxine-RIGHT__Pyridoxal-_r122
controller: Pyridoxine 4-oxidase

STATE_TRANSITION_LEFT__Pyridoxine_phosphate-RIGHT__Pyridoxine-_r126
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r126 88
participant stoichiometry: PARTICIPANT STOICHIOMETRY r126 87
left: Pyridoxine phosphate
interaction type: STATE_TRANSITION
right: Pyridoxine

PTHR43247:SF3
type: RelationshipXref
id: PTHR43247:SF3
db: PANTHER Family
relationship type: By Homology

PARTICIPANT STOICHIOMETRY r135 150
type: Stoichiometry
physical entity: Alpha-Hydroxymethyl succinate semialdehyde
stoichiometric coefficient: 1.0

uniprot H2QDB2 26
type: UnificationXref
id: H2QDB2
db: uniprot

PTHR43247:SF1
type: RelationshipXref
id: PTHR43247:SF1
db: PANTHER Family
relationship type: By Homology

PARTICIPANT STOICHIOMETRY r99 112
type: Stoichiometry
physical entity: Pyridoxal
stoichiometric coefficient: 1.0

3-Amino-2-oxopropyl phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

By Homology
type: RelationshipTypeVocabulary

Pyridoxal kinase
type: ProteinReference
xref: uniprot H9EWM2 68
xref: PTHR10534:SF2
organism: Macaca mulatta

ncbitaxon 9598 27
type: UnificationXref
id: 9598
db: ncbitaxon

Phosphoserine transaminase
type: Protein
entity reference: Phosphoserine transaminase
comment: SPECIES_TYPE=PROTEIN

Deinococcus radiodurans
type: BioSource
xref: ncbitaxon 243230 44

uniprot O14242 70
type: UnificationXref
id: O14242
db: uniprot

ncbitaxon 367110 57
type: UnificationXref
id: 367110
db: ncbitaxon

STATE_TRANSITION_LEFT__Pyridoxamine_5_phosphate-RIGHT__Pyridoxal_5_phosphate-_r105
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r105 144
participant stoichiometry: PARTICIPANT STOICHIOMETRY r105 143
left: Pyridoxamine 5-phosphate
interaction type: STATE_TRANSITION
right: Pyridoxal 5-phosphate

Pyridoxine/pyridoxamine 5'-phosphate oxidase
type: ProteinReference
xref: PTHR10851:SF0
xref: uniprot P74211 31
organism: Synechocystis

Homo sapiens
type: BioSource
xref: ncbitaxon 9606 22

PARTICIPANT STOICHIOMETRY r99 111
type: Stoichiometry
physical entity: 4-Pyridoxolactone
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r130 160
type: Stoichiometry
physical entity: Pyridoxine
stoichiometric coefficient: 1.0

Methanocaldococcus jannaschii
type: BioSource
xref: ncbitaxon 243232 60

2-Oxo-3-hydroxy 4-phosphobutaonate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

eco ECO:0000303 79
type: UnificationXref
id: ECO:0000303
db: eco

STATE_TRANSITION_LEFT__O_Phospho_4_hydroxy_L_threonine-RIGHT__4_Hydroxy_L_threonine-_r145
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r145 109
participant stoichiometry: PARTICIPANT STOICHIOMETRY r145 110
left: O-Phospho 4-hydroxy L-threonine
interaction type: STATE_TRANSITION
right: 4-Hydroxy L-threonine

uniprot E2QTE2 24
type: UnificationXref
id: E2QTE2
db: uniprot

STATE_TRANSITION_LEFT__O_Phospho_4_hydroxy_L_threonine-RIGHT__2_Oxo_3_hydroxy_4_phosphobutaonate-_r144
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r144 115
participant stoichiometry: PARTICIPANT STOICHIOMETRY r144 116
left: O-Phospho 4-hydroxy L-threonine
interaction type: STATE_TRANSITION
right: 2-Oxo-3-hydroxy 4-phosphobutaonate

PARTICIPANT STOICHIOMETRY r126 87
type: Stoichiometry
physical entity: Pyridoxine phosphate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r126 88
type: Stoichiometry
physical entity: Pyridoxine
stoichiometric coefficient: 1.0

Pyridoxal kinase PdxY
type: ProteinReference
xref: uniprot Q9HT57 81
xref: PTHR10534:SF2
organism: Pseudomonas aeruginosa

Arabidopsis thaliana
type: BioSource
xref: ncbitaxon 3702 18

uniprot Q8W1X2 80
type: UnificationXref
id: Q8W1X2
db: uniprot

Pyridoxine/pyridoxal/pyridoxamine kinase
type: ProteinReference
xref: uniprot P40191 73
xref: PTHR10534:SF15
organism: Escherichia coli

PARTICIPANT STOICHIOMETRY r130 159
type: Stoichiometry
physical entity: Glycoaldehyde
stoichiometric coefficient: 1.0

Pyridoxine 5-dehydrogenase
type: Protein
comment: SPECIES_TYPE=PROTEIN

PANTHER Pathway P02787 1
type: UnificationXref
id: P02787
db: PANTHER Pathway

KNOWN_TRANSITION_OMITTED_LEFT__Glycoaldehyde-RIGHT__Pyridoxine-_r130
type: Conversion
conversion direction: LEFT_TO_RIGHT
xref: KNOWN TRANSITION OMITTED
participant stoichiometry: PARTICIPANT STOICHIOMETRY r130 160
participant stoichiometry: PARTICIPANT STOICHIOMETRY r130 159
left: Glycoaldehyde
interaction type: KNOWN_TRANSITION_OMITTED
right: Pyridoxine

Pyridoxine 4-dehydrogenase
type: Protein
comment: SPECIES_TYPE=PROTEIN

Uncharacterized protein
type: ProteinReference
xref: uniprot D3Z8P5 65
xref: PTHR10534:SF2
organism: Rattus norvegicus

PARTICIPANT STOICHIOMETRY r123 94
type: Stoichiometry
physical entity: Pyridoxal 5-phosphate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r123 93
type: Stoichiometry
physical entity: Pyridoxal
stoichiometric coefficient: 1.0

Pyridoxal 5-phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Mycobacterium tuberculosis
type: BioSource
xref: ncbitaxon 83332 34

PARTICIPANT STOICHIOMETRY r147 107
type: Stoichiometry
physical entity: O-Phospho 4-hydroxy L-threonine
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r127 85
type: Stoichiometry
physical entity: Pyridoxamine
stoichiometric coefficient: 1.0

Threonine synthase
type: ProteinReference
xref: PTHR42690:SF1
xref: uniprot Q00063 54
organism: Ashbya gossypii

PARTICIPANT STOICHIOMETRY r147 108
type: Stoichiometry
physical entity: 3-Amino-2-oxopropyl phosphate
stoichiometric coefficient: 1.0

PTHR10534:SF15
type: RelationshipXref
id: PTHR10534:SF15
db: PANTHER Family
relationship type: By Homology

PARTICIPANT STOICHIOMETRY r127 86
type: Stoichiometry
physical entity: Pyridoxamine 5-phosphate
stoichiometric coefficient: 1.0

2-(Acetamidomethylene) 3-hydroxymethyl succinate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Pyridoxal kinase
type: ProteinReference
xref: P03244
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: Pyridoxal kinase Synonym: Synonym not specified Accession: P03244
comment: ENTITY_REFERENCE_ID_DESC=Vitamin B6 metabolism.PROTEIN.GENERIC.Pyridoxal_br_kinase
member entity reference: Pyridoxal kinase
member entity reference: Putative pyridoxal kinase C18.10
member entity reference: Pyridoxal kinase PdxY
member entity reference: Putative pyridoxal kinase C6F6.11c
member entity reference: Uncharacterized protein
member entity reference: Pyridoxine/pyridoxal/pyridoxamine kinase

PARTICIPANT STOICHIOMETRY r136 148
type: Stoichiometry
physical entity: 5-Pyridoxolactone
stoichiometric coefficient: 1.0

STATE_TRANSITION_LEFT__4_Pyridoxolactone-RIGHT__4_Pyridoxate-_r97
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r97 128
participant stoichiometry: PARTICIPANT STOICHIOMETRY r97 127
left: 4-Pyridoxolactone
interaction type: STATE_TRANSITION
right: 4-Pyridoxate

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Pyridoxine_phosphate-RIGHT__Pyridoxal_5_phosphate-_r112
controller: Pyridoxamine phosphate oxidase

uniprot A0A0G2K931 2
type: UnificationXref
id: A0A0G2K931
db: uniprot

Escherichia coli
type: BioSource
xref: ncbitaxon 83333 12

PARTICIPANT STOICHIOMETRY r136 147
type: Stoichiometry
physical entity: Isopyridoxal
stoichiometric coefficient: 1.0

uniprot P74211 31
type: UnificationXref
id: P74211
db: uniprot

Pyridoxamine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Phosphoserine aminotransferase
type: ProteinReference
xref: uniprot Q9Y617 21
xref: PTHR43247:SF5
organism: Homo sapiens

PARTICIPANT STOICHIOMETRY r87 153
type: Stoichiometry
physical entity: 2-(Acetamidomethylene) succinate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r87 154
type: Stoichiometry
physical entity: Succinate semialdehyde
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r145 110
type: Stoichiometry
physical entity: 4-Hydroxy L-threonine
stoichiometric coefficient: 1.0

Phosphoserine aminotransferase
type: ProteinReference
xref: uniprot P80862 15
xref: PTHR43247:SF1
organism: Bacillus subtilis

D-Erythrose 4-phosphate
type: SmallMolecule
cellular location: Pentose Phosphate Pathway c7
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Pyridoxal oxiadase
type: Protein
comment: SPECIES_TYPE=PROTEIN

Pyridoxal kinase PdxY
type: ProteinReference
xref: PTHR10534:SF2
xref: uniprot Q9RYX0 82
organism: Deinococcus radiodurans

IDA
type: EvidenceCodeVocabulary

KNOWN_TRANSITION_OMITTED_LEFT__D_Erythrose_4_phosphate-RIGHT__4_Phospho_D_erythronate-_r150
type: Conversion
conversion direction: LEFT_TO_RIGHT
xref: KNOWN TRANSITION OMITTED
participant stoichiometry: PARTICIPANT STOICHIOMETRY r150 102
participant stoichiometry: PARTICIPANT STOICHIOMETRY r150 101
left: D-Erythrose 4-phosphate
interaction type: KNOWN_TRANSITION_OMITTED
right: 4-Phospho D-erythronate

Phosphoserine aminotransferase
type: ProteinReference
xref: uniprot A0A3S5ZPF7 6
xref: PTHR43247:SF1
organism: Bos taurus

ncbitaxon 559292 14
type: UnificationXref
id: 559292
db: ncbitaxon

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Pyridoxamine_5_phosphate-RIGHT__Pyridoxamine-_r128
controller: Pyridoxal kinase

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Pyridoxamine-RIGHT__Pyridoxal-_r110
controller: Pyridoxamine oxaloacetate transaminase

ncbitaxon 224324 49
type: UnificationXref
id: 224324
db: ncbitaxon

PNPO isoform 1
type: ProteinReference
xref: PTHR10851:SF0
xref: uniprot H2QDB2 26
organism: Pan troglodytes

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Pyridoxamine_5_phosphate-RIGHT__Pyridoxal_5_phosphate-_r105
controller: Pyridoxamine phosphate oxidase

uniprot A0A1D5Q928 23
type: UnificationXref
id: A0A1D5Q928
db: uniprot

STATE_TRANSITION_LEFT__3_Hydroxy_4_hydroxymethyl_2_methylpyridine_5_carboxylate-RIGHT__2__Acetamidomethylene__3_hydroxymethyl_succinate-_r134
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r134 151
participant stoichiometry: PARTICIPANT STOICHIOMETRY r134 152
left: 3-Hydroxy-4-hydroxymethyl-2-methylpyridine 5-carboxylate
interaction type: STATE_TRANSITION
right: 2-(Acetamidomethylene) 3-hydroxymethyl succinate

4-Pyridoxolactone
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Succinate semialdehyde
type: SmallMolecule
cellular location: Butaonate Metabolism c4
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r91 139
type: Stoichiometry
physical entity: 3-Hydroxy-2 methylpyridine-5-carboxylate
stoichiometric coefficient: 1.0

Bacillus subtilis
type: BioSource
xref: ncbitaxon 224308 16

MODULATION
type: RelationshipTypeVocabulary

Pyridoxine/pyridoxamine 5'-phosphate oxidase
type: ProteinReference
xref: PTHR10851:SF0
xref: uniprot P0AFI7 28
organism: Escherichia coli

Dictyostelium discoideum
type: BioSource
xref: ncbitaxon 44689 77

uniprot Q0II59 75
type: UnificationXref
id: Q0II59
db: uniprot

Bos taurus
type: BioSource
xref: ncbitaxon 9913 7

Pyridoxine-5'-phosphate oxidase
type: ProteinReference
xref: PTHR10851:SF0
xref: uniprot Q5E9K3 35
organism: Bos taurus

Threonine synthase, putative
type: ProteinReference
xref: uniprot Q5KMM7 61
xref: PTHR42690:SF1
organism: Cryptococcus neoformans

Macaca mulatta
type: BioSource
xref: ncbitaxon 9544 10

uniprot Q9I4S5 37
type: UnificationXref
id: Q9I4S5
db: uniprot

Pyrodoxamine pyruvate transaminase
type: Protein
comment: SPECIES_TYPE=PROTEIN

KNOWN_TRANSITION_OMITTED_LEFT__4_Hydroxy_L_threonine-RIGHT__Pyridoxine-_r149
type: Conversion
conversion direction: LEFT_TO_RIGHT
xref: KNOWN TRANSITION OMITTED
participant stoichiometry: PARTICIPANT STOICHIOMETRY r149 103
participant stoichiometry: PARTICIPANT STOICHIOMETRY r149 104
left: 4-Hydroxy L-threonine
interaction type: KNOWN_TRANSITION_OMITTED
right: Pyridoxine

Pyridoxamine 5'-phosphate oxidase
type: ProteinReference
xref: PTHR10851:SF0
xref: uniprot P38075 30
organism: Saccharomyces cerevisiae

Phosphoserine transaminase
type: ProteinReference
xref: P03227
comment: ENTITY_REFERENCE_NOTES= Long Name: Phosphoserine transaminase Synonym: Synonym not specified Accession: P03227
comment: ENTITY_REFERENCE_ID_DESC=Vitamin B6 metabolism.PROTEIN.GENERIC.Phosphoserine_br_transaminase
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
member entity reference: Phosphoserine aminotransferase 1, chloroplastic
member entity reference: Phosphoserine aminotransferase

IEA
type: EvidenceCodeVocabulary
xref: eco ECO:0000501 47

KNOWN_TRANSITION_OMITTED_LEFT__Isopyridoxal-RIGHT__5_Pyridoxolactone-_r136
type: Conversion
conversion direction: LEFT_TO_RIGHT
xref: KNOWN TRANSITION OMITTED
participant stoichiometry: PARTICIPANT STOICHIOMETRY r136 148
participant stoichiometry: PARTICIPANT STOICHIOMETRY r136 147
left: Isopyridoxal
interaction type: KNOWN_TRANSITION_OMITTED
right: 5-Pyridoxolactone

Vitamin B6 metabolism
type: Pathway
pathway component: STATE_TRANSITION_LEFT__Pyridoxal_5_phosphate-RIGHT__Pyridoxal-_r124
pathway component: KNOWN_TRANSITION_OMITTED_LEFT__Isopyridoxal-RIGHT__5_Pyridoxolactone-_r136
pathway component: STATE_TRANSITION_LEFT__O_Phospho_4_hydroxy_L_threonine-RIGHT__2_Oxo_3_hydroxy_4_phosphobutaonate-_r144
pathway component: KNOWN_TRANSITION_OMITTED_LEFT__4_Pyridoxate-RIGHT__2_Methyl_3_Hydroxy_5_formylpyridine_4_carboxylate-_r94
pathway component: STATE_TRANSITION_LEFT__2_Oxo_3_hydroxy_4_phosphobutaonate-RIGHT__O_Phospho_4_hydroxy_L_threonine-_r143
pathway component: KNOWN_TRANSITION_OMITTED_LEFT__5_Pyridoxolactone-RIGHT__3_Hydroxy_4_hydroxymethyl_2_methylpyridine_5_carboxylate-_r137
pathway component: KNOWN_TRANSITION_OMITTED_LEFT__D_Erythrose_4_phosphate-RIGHT__4_Phospho_D_erythronate-_r150
pathway component: KNOWN_TRANSITION_OMITTED_LEFT__4_Hydroxy_L_threonine-RIGHT__Pyridoxine-_r149
pathway component: STATE_TRANSITION_LEFT__Pyridoxal-RIGHT__Pyridoxamine-_r100
pathway component: STATE_TRANSITION_LEFT__Pyridoxamine_5_phosphate-RIGHT__Pyridoxal_5_phosphate-_r105
pathway component: KNOWN_TRANSITION_OMITTED_LEFT__Glycoaldehyde-RIGHT__Pyridoxine-_r130
pathway component: STATE_TRANSITION_LEFT__3_Amino_2_oxopropyl_phosphate-RIGHT__Pyridoxine_phosphate-_r148
pathway component: STATE_TRANSITION_LEFT__Pyridoxine-RIGHT__Pyridoxal-_r122
pathway component: STATE_TRANSITION_LEFT__2_Oxoglutarate-_Pyridoxal_5_phosphate-_Pyruvate-RIGHT__D_Glutamate-_Pyridoxamine_5_phosphate-_D_Alanine-_r111
pathway component: STATE_TRANSITION_LEFT__Pyridoxine_phosphate-RIGHT__Pyridoxine-_r126
pathway component: STATE_TRANSITION_LEFT__O_Phospho_4_hydroxy_L_threonine-RIGHT__4_Hydroxy_L_threonine-_r145
pathway component: KNOWN_TRANSITION_OMITTED_LEFT__2_Methyl_3_Hydroxy_5_formylpyridine_4_carboxylate-RIGHT__3_Hydroxy_2_methylpyridine_4,5_dicarboxylate-_r93
pathway component: STATE_TRANSITION_LEFT__Pyridoxine-RIGHT__Isopyridoxal-_r131
pathway component: STATE_TRANSITION_LEFT__Pyridoxamine-RIGHT__Pyridoxamine_5_phosphate-_r127
pathway component: STATE_TRANSITION_LEFT__2__Acetamidomethylene__3_hydroxymethyl_succinate-RIGHT__Alpha_Hydroxymethyl_succinate_semialdehyde-_r135
pathway component: STATE_TRANSITION_LEFT__3_Hydroxy_2_methylpyridine_4,5_dicarboxylate-RIGHT__3_Hydroxy_2_methylpyridine_5_carboxylate-_r92
pathway component: STATE_TRANSITION_LEFT__4_Pyridoxolactone-RIGHT__4_Pyridoxate-_r97
pathway component: STATE_TRANSITION_LEFT__4_Pyridoxolactone-RIGHT__Pyridoxal-_r99
pathway component: STATE_TRANSITION_LEFT__Pyridoxal-RIGHT__4_Pyridoxolactone-_r98
pathway component: KNOWN_TRANSITION_OMITTED_LEFT__4_Phospho_D_erythronate-RIGHT__2_Oxo_3_hydroxy_4_phosphobutaonate-_r151
pathway component: STATE_TRANSITION_LEFT__2__Acetamidomethylene__succinate-RIGHT__Succinate_semialdehyde-_r87
pathway component: STATE_TRANSITION_LEFT__3_Hydroxy_4_hydroxymethyl_2_methylpyridine_5_carboxylate-RIGHT__2__Acetamidomethylene__3_hydroxymethyl_succinate-_r134
pathway component: STATE_TRANSITION_LEFT__Pyridoxamine_5_phosphate-RIGHT__Pyridoxamine-_r128
pathway component: STATE_TRANSITION_LEFT__3_Hydroxy_2_methylpyridine_5_carboxylate-RIGHT__2__Acetamidomethylene__succinate-_r91
pathway component: STATE_TRANSITION_LEFT__O_Phospho_4_hydroxy_L_threonine-RIGHT__3_Amino_2_oxopropyl_phosphate-_r147
pathway component: STATE_TRANSITION_LEFT__Pyridoxine-RIGHT__Pyridoxine_phosphate-_r125
pathway component: STATE_TRANSITION_LEFT__Pyridoxamine-RIGHT__Pyridoxal-_r110
pathway component: STATE_TRANSITION_LEFT__Pyridoxal-RIGHT__4_Pyridoxate-_r106
pathway component: STATE_TRANSITION_LEFT__Pyridoxal-RIGHT__Pyridoxine-_r121
pathway component: KNOWN_TRANSITION_OMITTED_LEFT__4_Pyridoxate-RIGHT__Excretion-_r96
pathway component: STATE_TRANSITION_LEFT__Pyridoxal-RIGHT__Pyridoxal_5_phosphate-_r123
pathway component: STATE_TRANSITION_LEFT__Pyridoxine_phosphate-RIGHT__Pyridoxal_5_phosphate-_r112
xref: PANTHER Pathway P02787 1
comment: MODEL_NOTES= Vitamin B6 is a collective name fore three substituted pyridines - pyridoxal, pyridoxol, and pyridoxamine. Pyridoxal carries an aldehyde group (-CHO) at C-4. Pyridoxol is the corresponding alcohol (-CH2OH), and pyridoxamine the homologous amine (-CH2NH2). The active form of vitamin B6, pyridoxal phosphate, is the most important coenzyme in amino acid metabolism. Glycogen phosphorylase, the enzyme catalyzing glycogen degradation, also contains pyridoxal phosphate. Vitamin B6 deficiency is very rare. Website=KEGG - Kyoto Encyclopedia of Genes and Genomes http://www.genome.jp/kegg/ free text=Biochemiscal Pathways - An Atlas of Biochemistry and Molecular Biology Edited by Gerhard Michal free text=Color Atlas of Biochemistry by Jan Koolman and Klaus-Heinrich Rohm free text=Human Metabolism by Ramsey Bronk

uniprot Q1K5C3 56
type: UnificationXref
id: Q1K5C3
db: uniprot

NAS
type: EvidenceCodeVocabulary
xref: eco ECO:0000303 79

Trypanosoma brucei
type: BioSource
xref: ncbitaxon 185431 67

Glycoaldehyde
type: SmallMolecule
cellular location: Glyoxylate and Dicarboxylate Metabolism c6
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Pyridoxine/pyridoxamine 5'-phosphate oxidase
type: ProteinReference
xref: PTHR10851:SF0
xref: uniprot Q9RX20 43
organism: Deinococcus radiodurans

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Pyridoxine-RIGHT__Isopyridoxal-_r131
controller: Pyridoxine 5-dehydrogenase

TAS
type: EvidenceCodeVocabulary
xref: eco ECO:0000304 4

PTHR10851:SF0
type: RelationshipXref
id: PTHR10851:SF0
db: PANTHER Family
relationship type: By Homology

2-Oxoglutarate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r91 140
type: Stoichiometry
physical entity: 2-(Acetamidomethylene) succinate
stoichiometric coefficient: 1.0

ncbitaxon 284811 55
type: UnificationXref
id: 284811
db: ncbitaxon

STATE_TRANSITION_LEFT__Pyridoxal-RIGHT__Pyridoxal_5_phosphate-_r123
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r123 94
participant stoichiometry: PARTICIPANT STOICHIOMETRY r123 93
left: Pyridoxal
interaction type: STATE_TRANSITION
right: Pyridoxal 5-phosphate

Pyridoxal 4-dehydrogenase
type: Protein
comment: SPECIES_TYPE=PROTEIN

uniprot Q9HT57 81
type: UnificationXref
id: Q9HT57
db: uniprot

Pyridoxamine phosphate oxidase
type: ProteinReference
xref: P03236
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Vitamin B6 metabolism.PROTEIN.GENERIC.Pyridoxamine_br_phosphate oxidase
comment: ENTITY_REFERENCE_NOTES= Long Name: Pyridoxamine phosphate oxidase Synonym: Synonym not specified Accession: P03236
member entity reference: Pyridoxine-5'-phosphate oxidase
member entity reference: Pyridoxine/pyridoxamine 5'-phosphate oxidase
member entity reference: Pyridoxine/pyridoxamine 5'-phosphate oxidase 1, chloroplastic
member entity reference: Probable pyridoxamine 5'-phosphate oxidase
member entity reference: Pyridoxine 5'-phosphate oxidase
member entity reference: Pyridoxamine 5'-phosphate oxidase
member entity reference: PNPO isoform 1

ncbitaxon 1111708 32
type: UnificationXref
id: 1111708
db: ncbitaxon

STATE_TRANSITION_LEFT__Pyridoxine-RIGHT__Isopyridoxal-_r131
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r131 158
participant stoichiometry: PARTICIPANT STOICHIOMETRY r131 157
left: Pyridoxine
interaction type: STATE_TRANSITION
right: Isopyridoxal

Pyridoxamine oxaloacetate transaminase
type: Protein
comment: SPECIES_TYPE=PROTEIN

STATE_TRANSITION_LEFT__3_Hydroxy_2_methylpyridine_5_carboxylate-RIGHT__2__Acetamidomethylene__succinate-_r91
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r91 140
participant stoichiometry: PARTICIPANT STOICHIOMETRY r91 139
left: 3-Hydroxy-2 methylpyridine-5-carboxylate
interaction type: STATE_TRANSITION
right: 2-(Acetamidomethylene) succinate

Pyridoxine/pyridoxamine 5'-phosphate oxidase
type: ProteinReference
xref: PTHR10851:SF0
xref: uniprot Q9I4S5 37
organism: Pseudomonas aeruginosa

ncbitaxon 9606 22
type: UnificationXref
id: 9606
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r128 84
type: Stoichiometry
physical entity: Pyridoxamine
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r128 83
type: Stoichiometry
physical entity: Pyridoxamine 5-phosphate
stoichiometric coefficient: 1.0

Rattus norvegicus
type: BioSource
xref: ncbitaxon 10116 3

uniprot Q5KMM7 61
type: UnificationXref
id: Q5KMM7
db: uniprot

Aquifex aeolicus
type: BioSource
xref: ncbitaxon 224324 49

PARTICIPANT STOICHIOMETRY r111 124
type: Stoichiometry
physical entity: D-Alanine
stoichiometric coefficient: 1.0

3-Hydroxy-2-methylpyridine 4,5-dicarboxylate 4-decarboxylase
type: Protein
comment: SPECIES_TYPE=PROTEIN

Canis lupus familiaris
type: BioSource
xref: ncbitaxon 9615 25

4-Phospho D-erythronate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r105 143
type: Stoichiometry
physical entity: Pyridoxamine 5-phosphate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r105 144
type: Stoichiometry
physical entity: Pyridoxal 5-phosphate
stoichiometric coefficient: 1.0

5-pyridoxate dioxygenase
type: Protein
comment: SPECIES_TYPE=PROTEIN

uniprot Q8K183 78
type: UnificationXref
id: Q8K183
db: uniprot

uniprot Q9K3V7 39
type: UnificationXref
id: Q9K3V7
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Pyridoxamine-RIGHT__Pyridoxal-_r110
controller: Pyrodoxamine pyruvate transaminase

KNOWN_TRANSITION_OMITTED_LEFT__4_Pyridoxate-RIGHT__2_Methyl_3_Hydroxy_5_formylpyridine_4_carboxylate-_r94
type: Conversion
conversion direction: LEFT_TO_RIGHT
xref: KNOWN TRANSITION OMITTED
participant stoichiometry: PARTICIPANT STOICHIOMETRY r94 133
participant stoichiometry: PARTICIPANT STOICHIOMETRY r94 134
left: 4-Pyridoxate
interaction type: KNOWN_TRANSITION_OMITTED
right: 2-Methyl-3-Hydroxy-5-formylpyridine-4-carboxylate

Threonine synthase
type: ProteinReference
xref: PTHR42690:SF1
xref: uniprot P16120 52
organism: Saccharomyces cerevisiae

uniprot P38075 30
type: UnificationXref
id: P38075
db: uniprot

Pyridoxine 5'-phosphate oxidase
type: ProteinReference
xref: PTHR10851:SF0
xref: uniprot P9WIJ1 33
organism: Mycobacterium tuberculosis

uniprot Q9Y617 21
type: UnificationXref
id: Q9Y617
db: uniprot

PARTICIPANT STOICHIOMETRY r145 109
type: Stoichiometry
physical entity: O-Phospho 4-hydroxy L-threonine
stoichiometric coefficient: 1.0

uniprot H9EWM2 68
type: UnificationXref
id: H9EWM2
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__4_Pyridoxolactone-RIGHT__4_Pyridoxate-_r97
controller: Pyridoxalactonase

uniprot P0AFI7 28
type: UnificationXref
id: P0AFI7
db: uniprot

STATE_TRANSITION_LEFT__Pyridoxal-RIGHT__4_Pyridoxolactone-_r98
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r98 118
participant stoichiometry: PARTICIPANT STOICHIOMETRY r98 117
left: Pyridoxal
interaction type: STATE_TRANSITION
right: 4-Pyridoxolactone

PARTICIPANT STOICHIOMETRY r134 152
type: Stoichiometry
physical entity: 2-(Acetamidomethylene) 3-hydroxymethyl succinate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r134 151
type: Stoichiometry
physical entity: 3-Hydroxy-4-hydroxymethyl-2-methylpyridine 5-carboxylate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r111 122
type: Stoichiometry
physical entity: D-Glutamate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r111 123
type: Stoichiometry
physical entity: Pyridoxamine 5-phosphate
stoichiometric coefficient: 1.0

Threonine synthase
type: ProteinReference
xref: PTHR42690:SF1
xref: uniprot Q9RYF8 63
organism: Deinococcus radiodurans

PARTICIPANT STOICHIOMETRY r111 120
type: Stoichiometry
physical entity: Pyridoxal 5-phosphate
stoichiometric coefficient: 1.0

Pyridoxamine 5-phosphate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

PARTICIPANT STOICHIOMETRY r111 121
type: Stoichiometry
physical entity: Pyruvate
stoichiometric coefficient: 1.0

Pyridoxalactonase
type: Protein
comment: SPECIES_TYPE=PROTEIN

PARTICIPANT STOICHIOMETRY r143 126
type: Stoichiometry
physical entity: O-Phospho 4-hydroxy L-threonine
stoichiometric coefficient: 1.0

eco ECO:0000501 47
type: UnificationXref
id: ECO:0000501
db: eco

PARTICIPANT STOICHIOMETRY r143 125
type: Stoichiometry
physical entity: 2-Oxo-3-hydroxy 4-phosphobutaonate
stoichiometric coefficient: 1.0

KNOWN_TRANSITION_OMITTED
type: RelationshipTypeVocabulary

STATE_TRANSITION_LEFT__Pyridoxine-RIGHT__Pyridoxine_phosphate-_r125
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r125 89
participant stoichiometry: PARTICIPANT STOICHIOMETRY r125 90
left: Pyridoxine
interaction type: STATE_TRANSITION
right: Pyridoxine phosphate

Isopyridoxal
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Threonine synthase
type: Protein
entity reference: Threonine synthase
comment: SPECIES_TYPE=PROTEIN

KNOWN_TRANSITION_OMITTED_LEFT__4_Phospho_D_erythronate-RIGHT__2_Oxo_3_hydroxy_4_phosphobutaonate-_r151
type: Conversion
conversion direction: LEFT_TO_RIGHT
xref: KNOWN TRANSITION OMITTED
participant stoichiometry: PARTICIPANT STOICHIOMETRY r151 100
participant stoichiometry: PARTICIPANT STOICHIOMETRY r151 99
left: 4-Phospho D-erythronate
interaction type: KNOWN_TRANSITION_OMITTED
right: 2-Oxo-3-hydroxy 4-phosphobutaonate

Phosphoserine aminotransferase 1, chloroplastic
type: ProteinReference
xref: uniprot Q96255 17
xref: PTHR43247:SF3
organism: Arabidopsis thaliana

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__O_Phospho_4_hydroxy_L_threonine-RIGHT__3_Amino_2_oxopropyl_phosphate-_r147
controller: 4-hydroxythreonine-4-phosphate dehydrogenase

Butaonate Metabolism c4
type: CellularLocationVocabulary
comment: Butaonate Metabolism

Phosphoserine aminotransferase
type: ProteinReference
xref: uniprot F7H2J8 9
xref: PTHR43247:SF1
organism: Macaca mulatta

uniprot A0A3S5ZPF7 6
type: UnificationXref
id: A0A3S5ZPF7
db: uniprot

uniprot Q9RX20 43
type: UnificationXref
id: Q9RX20
db: uniprot

PARTICIPANT STOICHIOMETRY r100 156
type: Stoichiometry
physical entity: Pyridoxamine
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r111 119
type: Stoichiometry
physical entity: 2-Oxoglutarate
stoichiometric coefficient: 1.0

Pyridoxal kinase
type: ProteinReference
xref: uniprot D6XI07 66
xref: PTHR10534:SF2
organism: Trypanosoma brucei

Streptomyces coelicolor
type: BioSource
xref: ncbitaxon 100226 40

PARTICIPANT STOICHIOMETRY r100 155
type: Stoichiometry
physical entity: Pyridoxal
stoichiometric coefficient: 1.0

uniprot O66740 48
type: UnificationXref
id: O66740
db: uniprot

STATE_TRANSITION_LEFT__Pyridoxamine-RIGHT__Pyridoxal-_r110
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r110 129
participant stoichiometry: PARTICIPANT STOICHIOMETRY r110 130
left: Pyridoxamine
interaction type: STATE_TRANSITION
right: Pyridoxal

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__4_Pyridoxolactone-RIGHT__Pyridoxal-_r99
controller: Pyridoxal 4-dehydrogenase

Pyridoxamine phosphate oxidase
type: Protein
entity reference: Pyridoxamine phosphate oxidase
comment: SPECIES_TYPE=PROTEIN

4-Pyridoxate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot Q99K85 19
type: UnificationXref
id: Q99K85
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Pyridoxamine-RIGHT__Pyridoxal-_r110
controller: Pyridoxamine phosphate oxidase

uniprot Q9RYX0 82
type: UnificationXref
id: Q9RYX0
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__O_Phospho_4_hydroxy_L_threonine-RIGHT__4_Hydroxy_L_threonine-_r145
controller: Threonine synthase

ncbitaxon 208964 38
type: UnificationXref
id: 208964
db: ncbitaxon

Excretion
type: PhysicalEntity
comment: SPECIES_TYPE=UNKNOWN

PTHR10314:SF96
type: RelationshipXref
id: PTHR10314:SF96
db: PANTHER Family
relationship type: By Homology

STATE_TRANSITION
type: RelationshipTypeVocabulary

STATE_TRANSITION
type: InteractionVocabulary

STATE_TRANSITION_LEFT__4_Pyridoxolactone-RIGHT__Pyridoxal-_r99
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r99 112
participant stoichiometry: PARTICIPANT STOICHIOMETRY r99 111
left: 4-Pyridoxolactone
interaction type: STATE_TRANSITION
right: Pyridoxal

P03244
type: UnificationXref
id: P03244
db: PANTHER Pathway Component

P03242
type: UnificationXref
id: P03242
db: PANTHER Pathway Component

ncbitaxon 10090 20
type: UnificationXref
id: 10090
db: ncbitaxon

uniprot Q91XF0 36
type: UnificationXref
id: Q91XF0
db: uniprot

STATE_TRANSITION_LEFT__Pyridoxamine_5_phosphate-RIGHT__Pyridoxamine-_r128
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r128 84
participant stoichiometry: PARTICIPANT STOICHIOMETRY r128 83
left: Pyridoxamine 5-phosphate
interaction type: STATE_TRANSITION
right: Pyridoxamine

uniprot O00764 69
type: UnificationXref
id: O00764
db: uniprot

Pyridoxine/pyridoxamine 5'-phosphate oxidase 1, chloroplastic
type: ProteinReference
xref: PTHR10851:SF0
xref: uniprot Q9LTX3 41
organism: Arabidopsis thaliana

PARTICIPANT STOICHIOMETRY r149 104
type: Stoichiometry
physical entity: Pyridoxine
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r149 103
type: Stoichiometry
physical entity: 4-Hydroxy L-threonine
stoichiometric coefficient: 1.0

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Pyridoxine-RIGHT__Pyridoxal-_r122
controller: Pyridoxamine phosphate oxidase

uniprot Q9NVS9 42
type: UnificationXref
id: Q9NVS9
db: uniprot

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__Pyridoxal-RIGHT__4_Pyridoxate-_r106
controller: Pyridoxal oxiadase

2-Methyl-3-Hydroxy-5-formylpyridine-4-carboxylate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

O-Phospho 4-hydroxy L-threonine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

eco ECO:0000304 4
type: UnificationXref
id: ECO:0000304
db: eco

PARTICIPANT STOICHIOMETRY r112 113
type: Stoichiometry
physical entity: Pyridoxine phosphate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r112 114
type: Stoichiometry
physical entity: Pyridoxal 5-phosphate
stoichiometric coefficient: 1.0

KNOWN_TRANSITION_OMITTED
type: InteractionVocabulary

PARTICIPANT STOICHIOMETRY r151 99
type: Stoichiometry
physical entity: 4-Phospho D-erythronate
stoichiometric coefficient: 1.0

uniprot D3Z8P5 65
type: UnificationXref
id: D3Z8P5
db: uniprot

ncbitaxon 83333 12
type: UnificationXref
id: 83333
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r98 117
type: Stoichiometry
physical entity: Pyridoxal
stoichiometric coefficient: 1.0

Pyridoxal kinase
type: ProteinReference
xref: uniprot Q8W1X2 80
xref: PTHR10534:SF2
organism: Arabidopsis thaliana

PARTICIPANT STOICHIOMETRY r98 118
type: Stoichiometry
physical entity: 4-Pyridoxolactone
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r96 132
type: Stoichiometry
physical entity: Excretion
stoichiometric coefficient: 1.0

Putative pyridoxal kinase C6F6.11c
type: ProteinReference
xref: uniprot O14242 70
xref: PTHR10534:SF2
organism: Schizosaccharomyces pombe

PARTICIPANT STOICHIOMETRY r96 131
type: Stoichiometry
physical entity: 4-Pyridoxate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r110 130
type: Stoichiometry
physical entity: Pyridoxal
stoichiometric coefficient: 1.0

uniprot P9WIJ1 33
type: UnificationXref
id: P9WIJ1
db: uniprot

ncbitaxon 100226 40
type: UnificationXref
id: 100226
db: ncbitaxon

uniprot P33330 13
type: UnificationXref
id: P33330
db: uniprot

Threonine synthase
type: ProteinReference
xref: PTHR42690:SF1
xref: uniprot Q1K5C3 56
organism: Neurospora crassa

uniprot Q55EK9 76
type: UnificationXref
id: Q55EK9
db: uniprot

Phosphoserine aminotransferase
type: ProteinReference
xref: uniprot Q99K85 19
xref: PTHR43247:SF1
organism: Mus musculus

Pyridoxine-5'-phosphate oxidase
type: ProteinReference
xref: PTHR10851:SF0
xref: uniprot Q9NVS9 42
organism: Homo sapiens

PARTICIPANT STOICHIOMETRY r122 95
type: Stoichiometry
physical entity: Pyridoxine
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r151 100
type: Stoichiometry
physical entity: 2-Oxo-3-hydroxy 4-phosphobutaonate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r97 128
type: Stoichiometry
physical entity: 4-Pyridoxate
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r97 127
type: Stoichiometry
physical entity: 4-Pyridoxolactone
stoichiometric coefficient: 1.0

Pyridoxal kinase
type: ProteinReference
xref: uniprot O35331 71
xref: PTHR10534:SF2
organism: Rattus norvegicus

Threonine synthase
type: ProteinReference
xref: uniprot P00934 51
xref: PTHR42690:SF1
organism: Escherichia coli

ncbitaxon 214684 62
type: UnificationXref
id: 214684
db: ncbitaxon

5-Pyridoxolactone
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Pyridoxal kinase PdxY
type: ProteinReference
xref: PTHR10534:SF2
xref: uniprot P77150 74
organism: Escherichia coli

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__2_Oxoglutarate-_Pyridoxal_5_phosphate-_Pyruvate-RIGHT__D_Glutamate-_Pyridoxamine_5_phosphate-_D_Alanine-_r111
controller: Pyridoxamine phosphate transaminase

2-(hydroxymethyl) 3-(acetamidomethylene) succinate hydrolase
type: Protein
comment: SPECIES_TYPE=PROTEIN

Pyridoxal kinase
type: Protein
entity reference: Pyridoxal kinase
comment: SPECIES_TYPE=PROTEIN

P03227
type: UnificationXref
id: P03227
db: PANTHER Pathway Component

uniprot P16120 52
type: UnificationXref
id: P16120
db: uniprot

STATE_TRANSITION_LEFT__Pyridoxal-RIGHT__Pyridoxine-_r121
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r121 98
participant stoichiometry: PARTICIPANT STOICHIOMETRY r121 97
left: Pyridoxal
interaction type: STATE_TRANSITION
right: Pyridoxine

uniprot Q00063 54
type: UnificationXref
id: Q00063
db: uniprot

uniprot Q9LTX3 41
type: UnificationXref
id: Q9LTX3
db: uniprot

uniprot Q42598 58
type: UnificationXref
id: Q42598
db: uniprot

STATE_TRANSITION_LEFT__2__Acetamidomethylene__3_hydroxymethyl_succinate-RIGHT__Alpha_Hydroxymethyl_succinate_semialdehyde-_r135
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r135 149
participant stoichiometry: PARTICIPANT STOICHIOMETRY r135 150
left: 2-(Acetamidomethylene) 3-hydroxymethyl succinate
interaction type: STATE_TRANSITION
right: Alpha-Hydroxymethyl succinate semialdehyde

Pentose Phosphate Pathway c7
type: CellularLocationVocabulary
comment: Pentose Phosphate Pathway

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__3_Hydroxy_2_methylpyridine_5_carboxylate-RIGHT__2__Acetamidomethylene__succinate-_r91
controller: 3-Hydroxy-2-methylpyridine carboxylate dioxygenase

STATE_TRANSITION_LEFT__Pyridoxine-RIGHT__Pyridoxal-_r122
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r122 96
participant stoichiometry: PARTICIPANT STOICHIOMETRY r122 95
left: Pyridoxine
interaction type: STATE_TRANSITION
right: Pyridoxal

Glyoxylate and Dicarboxylate Metabolism c6
type: CellularLocationVocabulary
comment: Glyoxylate and Dicarboxylate Metabolism

2-(Acetamidomethylene) succinate
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

STATE_TRANSITION_LEFT__Pyridoxal-RIGHT__Pyridoxamine-_r100
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r100 156
participant stoichiometry: PARTICIPANT STOICHIOMETRY r100 155
left: Pyridoxal
interaction type: STATE_TRANSITION
right: Pyridoxamine

PARTICIPANT STOICHIOMETRY r106 141
type: Stoichiometry
physical entity: Pyridoxal
stoichiometric coefficient: 1.0

eco ECO:0000250 8
type: UnificationXref
id: ECO:0000250
db: eco

Alpha-Hydroxymethyl succinate semialdehyde
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

ncbitaxon 243232 60
type: UnificationXref
id: 243232
db: ncbitaxon

PARTICIPANT STOICHIOMETRY r106 142
type: Stoichiometry
physical entity: 4-Pyridoxate
stoichiometric coefficient: 1.0

2-(Acetamidomethylene) succinate hydrolase
type: Protein
comment: SPECIES_TYPE=PROTEIN

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__2__Acetamidomethylene__3_hydroxymethyl_succinate-RIGHT__Alpha_Hydroxymethyl_succinate_semialdehyde-_r135
controller: 2-(hydroxymethyl) 3-(acetamidomethylene) succinate hydrolase

Pseudomonas aeruginosa
type: BioSource
xref: ncbitaxon 208964 38

Putative pyridoxal kinase C18.10
type: ProteinReference
xref: uniprot O74860 72
xref: PTHR10534:SF2
organism: Schizosaccharomyces pombe

STATE_TRANSITION_LEFT__2_Oxo_3_hydroxy_4_phosphobutaonate-RIGHT__O_Phospho_4_hydroxy_L_threonine-_r143
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r143 125
participant stoichiometry: PARTICIPANT STOICHIOMETRY r143 126
left: 2-Oxo-3-hydroxy 4-phosphobutaonate
interaction type: STATE_TRANSITION
right: O-Phospho 4-hydroxy L-threonine

ncbitaxon 83332 34
type: UnificationXref
id: 83332
db: ncbitaxon

ncbitaxon 243230 44
type: UnificationXref
id: 243230
db: ncbitaxon

3-Hydroxy-2-methylpyridine carboxylate dioxygenase
type: Protein
comment: SPECIES_TYPE=PROTEIN

PARTICIPANT STOICHIOMETRY r110 129
type: Stoichiometry
physical entity: Pyridoxamine
stoichiometric coefficient: 1.0

4-Hydroxy L-threonine
type: SmallMolecule
comment: SPECIES_TYPE=SIMPLE_MOLECULE

P03236
type: UnificationXref
id: P03236
db: PANTHER Pathway Component