Growth arrest and DNA damage inducible gamma
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.SIRT_minus_1
ENTITY_REFERENCE_NOTES=Long Name: Sirtuin Synonym: Sir2 Accession: P04632
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit
ENTITY_REFERENCE_NOTES=Long Name: Seven in absentia homolog 1 Synonym: Synonym not specified Accession: G04696
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.Siah
Tumor necrosis factor receptor superfamily member 6
ENTITY_REFERENCE_NOTES=Long Name: Cyclin G Synonym: CCNG,Cyclin G1 Accession: G04689
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.Cyclin G
3-phosphoinositide dependent protein kinase 1
Non-specific serine/threonine protein kinase
Growth arrest and DNA damage-inducible protein GADD45 gamma
ENTITY_REFERENCE_NOTES=Long Name: p53 Synonym: Synonym not specified Accession: G04702
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.p53
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.14-3-3
ENTITY_REFERENCE_NOTES=Long Name: 14-3-3 Synonym: Synonym not specified Accession: P04628
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.P21
ENTITY_REFERENCE_NOTES=Long Name: Cyclin-dependent kinase inhibitor 1A Synonym: CDK-interacting protein 1,CDKN1A,CIP1,Waf1,Wildteype p53-activated fragment 1,p21 Accession: P04631
ENTITY_REFERENCE_NOTES=Long Name: Cyclin B Synonym: Synonym not specified Accession: P04614
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.Cyclin B
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.PAI
ENTITY_REFERENCE_NOTES=Long Name: Plasminogen activator inhibitor 1 Synonym: Serpine 1 Accession: G04700
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.P300
ENTITY_REFERENCE_NOTES=Long Name: P300 Synonym: E1A-binding protein, 300-kD,EP300 Accession: P04611
ENTITY_REFERENCE_NOTES=Long Name: Histon deacetylase 1 Synonym: HD1,RPD3-like Accession: P04612
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.HDAC1
DNA Damage Stress Telomere shortening UV
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
3-phosphoinositide-dependent protein kinase 1
p53 apoptosis effector related to PMP-22
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.PTEN
ENTITY_REFERENCE_NOTES=Long Name: PTEN Synonym: Synonym not specified Accession: G01579
Apoptosis-inducing factor, mitochondria-associated 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Serine/threonine-protein phosphatase PP2A
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18
Spindle damage rNTP depletion Nitric oxide and inflammation Hypoxia
Growth arrest and DNA damage-inducible protein GADD45 beta
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.TSP1
ENTITY_REFERENCE_NOTES=Long Name: Thrombospondin-1 Synonym: Synonym not specified Accession: G01566
SIN3 transcription regulator family member A
Growth arrest and DNA damage-inducible protein GADD45 alpha
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN2A
Insulin-like growth factor-binding protein 3
Growth arrest and DNA damage inducible beta
High-mobility group (nonhistone chromosomal) protein 1-like 1
RAC-gamma serine/threonine-protein kinase
NAD-dependent protein deacetylase sirtuin-1
Putative tyrosine-protein phosphatase TPTE
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN1
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
RAC-alpha serine/threonine-protein kinase
RAC-beta serine/threonine-protein kinase
Growth arrest and DNA-damage-inducible 45 beta
Phosphatase and tensin homolog deleted on chromosome 10
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.PTEN
ENTITY_REFERENCE_NOTES=Long Name: Phosphatase and tensin homolog deleted on chromosome 10 Synonym: Synonym not specified Accession: P01480
Werner syndrome ATP-dependent helicase homolog
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.Cdk2
ENTITY_REFERENCE_NOTES=Long Name: Maspin Synonym: Mp Accession: G01569
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.Maspin
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.BAX
ENTITY_REFERENCE_NOTES=Long Name: BCL2-associated X protein Synonym: Synonym not specified Accession: G01581
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.p110_alpha_
ENTITY_REFERENCE_NOTES=Long Name: p110alpha Synonym: P110-alpha,PIK3CA Accession: G04694
ENTITY_REFERENCE_NOTES=Long Name: p53 Synonym: Synonym not specified Accession: P01485 Pathway Link: P00006|P00273|Apoptosis signaling pathway*P00033|P04497|Insulin/IGF pathway-protein kinase B signaling cascade*P04397|P04640|p53 pathway by glucose deprivation*P04398|P04668|p53 pathway feedback loops 2*P04392|P04539|P53 pathway feedback loops 1
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.p53
ENTITY_REFERENCE_NOTES=Long Name: Small ubiquitin-like modifier 1 Synonym: PIC1,SMT3 homolog 3,SUMO1,Sentrin,UBL1,Ubiquitin-like 1 Accession: P04635
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.Sumo_minus_1_br_ligase
ENTITY_REFERENCE_NOTES=Long Name: High mobility group protein 1 Synonym: Amphoterin,HMGB1,High mobility group box 1,Nonhistone chromosomal protein HMG1 Accession: P04619
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.HMG1
ENTITY_REFERENCE_NOTES=Long Name: Cyclin-dependent kinase inhibitor 1A Synonym: p21CIP1,p21WAF1 Accession: G01580
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.p21
ENTITY_REFERENCE_NOTES=Long Name: BAI-1 Synonym: Synonym not specified Accession: G04699
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.BAI_minus_1
ENTITY_REFERENCE_NOTES=Long Name: Cell division cycle 25C Synonym: Mitosis incucer CDC25 Accession: P04624
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.Cdc25C
ENTITY_REFERENCE_NOTES=Long Name: Cell division cycle 2 Synonym: Cdk1,Cell cycle controller,Cyclin-dependent kinase 1,P34 Accession: P04634
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.Cdc2
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.ARF
ENTITY_REFERENCE_NOTES=Long Name: Alternative reading frame (tumor-suppresor protein) Synonym: Cyclin-dependent kinase inhibitor 2A,p14ARF(humans),p19ARF (mouse) Accession: P01482 Pathway Link: P04393|P04576|Ras Pathway*P04398|P04655|p53 pathway feedback loops 2
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.WRN
ENTITY_REFERENCE_NOTES=Long Name: WRN gene Synonym: DNA helicase, RECQ-like, type 3,RECQ3,RECQL2 Accession: P04617
Metastasis-associated 1 family, member 2
3-phosphoinositide-dependent protein kinase 1 and 2
ENTITY_REFERENCE_NOTES=Long Name: 3-phosphoinositide-dependent protein kinase 1 and 2 Synonym: Synonym not specified Accession: P04616
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.PDK1_slash_2
Ribonucleoside-diphosphate reductase subunit M2
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.B99
ENTITY_REFERENCE_NOTES=Long Name: B99 Synonym: Gtse1 Accession: G04697
Growth arrest and DNA damage-inducible gamma
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.PP2A
ENTITY_REFERENCE_NOTES=Long Name: Protein phosphatase 2A Synonym: Synonym not specified Accession: P04630
Tumor necrosis factor receptor superfamily member 10B
Ribonucleotide reductase regulatory subunit M2
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.IGF_minus_BP3
ENTITY_REFERENCE_NOTES=Long Name: Insulin-like growth factor-binding protein 3 Synonym: IBP3,IGFBP3 Accession: G04691
Growth arrest and DNA-damage-inducible, alpha, a
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.PAG608
ENTITY_REFERENCE_NOTES=Long Name: Wildtype p53-induced gene Synonym: WIG1,p53-activated gene 608 Accession: G04690
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.PERP
ENTITY_REFERENCE_NOTES=Long Name: p53 apoptosis effector related to PMP-22 Synonym: Synonym not specified Accession: G01565
Tumor necrosis factor receptor superfamily member 10A
Cell division related protein kinase 2, putative
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.R2
ENTITY_REFERENCE_NOTES=Long Name: p53-inducible ribonucleotide reductase small subunit 2-like Synonym: RRM2B,Ribonucleotide reductase, M2 B,p53R2 Accession: G04692
p53-inducible ribonucleotide reductase small subunit 2-like
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.Akt
ENTITY_REFERENCE_NOTES=Long Name: V-akt murine thymoma viral oncogene homolog Synonym: PKB,Protein kinase B Accession: P01486 Pathway Link: P00033|P00894|Insulin/IGF pathway-protein kinase B signaling cascade*P04397|P04641|p53 pathway by glucose deprivation*P04398|P04665|p53 pathway feedback loops 2
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.CBP
ENTITY_REFERENCE_NOTES=Long Name: CREB binding protein Synonym: CREB binding protein Accession: P04623
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.E2F_minus_1
ENTITY_REFERENCE_NOTES=Long Name: E2F transcription factor 1 Synonym: Transcription factor E2F Accession: P04627
BCL2-associated X, apoptosis regulator a
ENTITY_REFERENCE_NOTES=Long Name: PML Synonym: Synonym not specified Accession: G04701
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.PML
ENTITY_REFERENCE_NOTES=Long Name: p300/CBP-associated factor Synonym: P/CAF Accession: P04629
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.PCAF
ENTITY_REFERENCE_NOTES=Long Name: Kangai 1 Synonym: CD82,Leukocyte surface antigen R2,SAR2,ST6,Suppressor of tumorigenicity 6 Accession: G04704
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.KAI
Growth arrest and DNA-damage-inducible, alpha
ENTITY_REFERENCE_NOTES=Long Name: Growth arrest-and DNA-damage-inducible, alpha Synonym: Synonym not specified Accession: P04626
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.GADD45
ENTITY_REFERENCE_NOTES=Long Name: NOXA Synonym: Synonym not specified Accession: G01572
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.NOXA
ENTITY_REFERENCE_NOTES=Long Name: TRAF Synonym: TRAP Accession: P04620
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.TRAF
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.Apaf
ENTITY_REFERENCE_NOTES=Long Name: Apoptotic protease activating factor 1 Synonym: Synonym not specified Accession: G04703
Phorbol-12-myristate-13-acetate-induced protein 1
Cell division control protein 2 homolog 2
Ataxia telangiectasia mutated (ATM) and Rad3-related (ATR)
ENTITY_REFERENCE_NOTES=Long Name: Ataxia telangiectasia mutated (ATM) and Rad3-related (ATR) Synonym: Synonym not specified Accession: P01481
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.ATM/ATR
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.B99
ENTITY_REFERENCE_NOTES=Long Name: G2- and S- phase expressed gene 1 Synonym: Gtse1 Accession: P04613
ENTITY_REFERENCE_NOTES=Long Name: 14-3-3 sigma Synonym: Synonym not specified Accession: G01576
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.14-3-3
ENTITY_REFERENCE_NOTES=Long Name: Checkpoint kinase 2 Synonym: Synonym not specified Accession: P01484
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.Chk2
ENTITY_REFERENCE_NOTES=Long Name: Mouse double minute 2 Synonym: Synonym not specified Accession: P01483 Pathway Link: P00033|P04496|Insulin/IGF pathway-protein kinase B signaling cascade*P04398|P04663|p53 pathway feedback loops 2*P04392|P04536|P53 pathway feedback loops 1
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.Mdm2
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.Cyclin E
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.GADD45
ENTITY_REFERENCE_NOTES=Long Name: Growth arrest and DNA-damage-inducible, alpha Synonym: Synonym not specified Accession: G01575
ENTITY_REFERENCE_NOTES=Long Name: Metastasis-associated 2 Synonym: MTA1L1,MTA2,Metastasis-associated protein 1-like,PID Accession: P04615
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.MTA2
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.PML
ENTITY_REFERENCE_NOTES=Long Name: Promyelocytic leukemia protein Synonym: Synonym not specified Accession: P04618
ENTITY_REFERENCE_NOTES=Long Name: DNA damage-binding protein 2 Synonym: DDB2 Accession: G04705
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.p48
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.FAS
ENTITY_REFERENCE_NOTES=Long Name: APO-1 or CD95 Synonym: APO-1, CD95 Accession: G01571
CHK2 checkpoint homolog (S. pombe), isoform CRA_a
ENTITY_REFERENCE_NOTES=Long Name: KILLER/death receptor (DR)5 Synonym: Synonym not specified Accession: G01568
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.KILLER/DR5
ENTITY_REFERENCE_NOTES=Long Name: ARF Synonym: Cyclin-dependent kinase inhibitor 2A,p14ARF(humans),p19ARF (mouse) Accession: G01574
ENTITY_REFERENCE_ID_DESC=p53 pathway.GENE.GENE.ARF
Inhibition of Angiogenesis and Metastasis
Phosphatidylinositol 3-kinase, catalytic subunit, alpha
ENTITY_REFERENCE_NOTES=Long Name: Phosphatidylinositol 3-kinase, catalytic subunit, alpha Synonym: P110-alpha,PIK3CA Accession: P04633
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.P110_alpha_
Histone deacetylase complex subunit Sin3
ENTITY_REFERENCE_ID_DESC=p53 pathway.PROTEIN.GENERIC.Sin3
ENTITY_REFERENCE_NOTES=Long Name: Sin3 Synonym: Synonym not specified Accession: P04622