uniprot Q9BQ50 150
type: UnificationXref
id: Q9BQ50
db: uniprot

ncbitaxon 44689 493
type: UnificationXref
id: 44689
db: ncbitaxon

ncbitaxon 188937 140
type: UnificationXref
id: 188937
db: ncbitaxon

26S proteasome non-ATPase regulatory subunit 13
type: ProteinReference
xref: uniprot Q9WVJ2 170
xref: PTHR10539:SF0
organism: Mus musculus

Eukaryotic translation initiation factor 3 subunit F
type: ProteinReference
xref: uniprot O04202 71
organism: Arabidopsis thaliana

uniprot O74762 82
type: UnificationXref
id: O74762
db: uniprot

uniprot F6Y460 543
type: UnificationXref
id: F6Y460
db: uniprot

uniprot E2R837 537
type: UnificationXref
id: E2R837
db: uniprot

PTHR24068:SF43
type: RelationshipXref
id: PTHR24068:SF43
db: PANTHER Family
relationship type: By Homology

uniprot Q9MAK9 156
type: UnificationXref
id: Q9MAK9
db: uniprot

Ubiquitin conjugating enzyme E2 D2
type: ProteinReference
xref: uniprot J9NS22 378
organism: Canis lupus familiaris

uniprot Q4QDA3 115
type: UnificationXref
id: Q4QDA3
db: uniprot

Lysine Protein target s15 a22 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Lysine
feature location: Lysine Protein target s15 a22 rs1 Lysine
modification type: MODIFICATION FEATURE ubiquitinated
comment: MODIFICATION_RESIDUE_NAME=Lysine
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=0.7454189465414205

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A1L1RJI2 179
organism: Gallus gallus

26S proteasome regulatory subunit 4 homolog A
type: ProteinReference
xref: uniprot Q9SZD4 166
organism: Arabidopsis thaliana

SUMO-activating enzyme subunit 1
type: ProteinReference
xref: uniprot A2VE14 533
organism: Bos taurus

uniprot Q921J4 503
type: UnificationXref
id: Q921J4
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F6SSD2 335
organism: Monodelphis domestica

uniprot Q7Z3V4 258
type: UnificationXref
id: Q7Z3V4
db: uniprot

Ubiquitin-conjugating enzyme E2 variant 1D
type: ProteinReference
xref: uniprot Q9SVD7 523
organism: Arabidopsis thaliana

uniprot Q32PA5 455
type: UnificationXref
id: Q32PA5
db: uniprot

uniprot A0A0G2K612 175
type: UnificationXref
id: A0A0G2K612
db: uniprot

uniprot F7GIS4 360
type: UnificationXref
id: F7GIS4
db: uniprot

UBE3B isoform 1
type: ProteinReference
xref: uniprot K7D8I3 232
organism: Pan troglodytes

uniprot Q6Z875 130
type: UnificationXref
id: Q6Z875
db: uniprot

Ubiquitin conjugating enzyme E2 E1
type: ProteinReference
xref: uniprot E2QXE6 317
organism: Canis lupus familiaris

Ubiquitin-activating enzyme E1 1
type: ProteinReference
xref: uniprot P93028 565
organism: Arabidopsis thaliana

Mus musculus
type: BioSource
xref: ncbitaxon 10090 75

Ubiquitin conjugating enzyme E2 D4 (putative)
type: ProteinReference
xref: uniprot F6VSA5 341
organism: Monodelphis domestica

Ubiquitin-like modifier-activating enzyme ATG7
type: ProteinReference
xref: uniprot F7ESQ7 548
organism: Macaca mulatta

26S proteasome non-ATPase regulatory subunit 1
type: ProteinReference
xref: uniprot Q5F418 122
organism: Gallus gallus

uniprot Q3T030 602
type: UnificationXref
id: Q3T030
db: uniprot

uniprot A9TVX5 31
type: UnificationXref
id: A9TVX5
db: uniprot

uniprot F6PPG7 330
type: UnificationXref
id: F6PPG7
db: uniprot

Predicted protein
type: ProteinReference
xref: uniprot A9U4R7 303
organism: Physcomitrella patens

Ubiquitin protein ligase E3C
type: ProteinReference
xref: uniprot F1PB35 205
organism: Canis lupus familiaris

E3 ubiquitin-protein ligase
type: ProteinReference
xref: PTHR11254:SF300
xref: uniprot F7A9B7 216
organism: Macaca mulatta

uniprot Q4FZT9 114
type: UnificationXref
id: Q4FZT9
db: uniprot

ncbitaxon 559292 92
type: UnificationXref
id: 559292
db: ncbitaxon

uniprot A8X150 292
type: UnificationXref
id: A8X150
db: uniprot

E3 ubiquitin-protein ligase Mdm2
type: ProteinReference
xref: PTHR13844:SF15
xref: uniprot F1MYE6 200
organism: Bos taurus

PTHR24068:SF67
type: RelationshipXref
id: PTHR24068:SF67
db: PANTHER Family
relationship type: By Homology

Ubiquitin-conjugating enzyme E2 D4
type: ProteinReference
xref: uniprot Q9Y2X8 527
organism: Homo sapiens

Ubiquitin-protein ligase E3A
type: ProteinReference
xref: uniprot Q05086 250
organism: Homo sapiens

26S proteasome non-ATPase regulatory subunit 6
type: ProteinReference
xref: uniprot Q8W425 145
organism: Oryza sativa

uniprot F1NFN4 203
type: UnificationXref
id: F1NFN4
db: uniprot

UBE2D2 isoform 7
type: ProteinReference
xref: uniprot A0A2I3S6N5 280
organism: Pan troglodytes

Ubiquitin/ISG15-conjugating enzyme E2 L6
type: ProteinReference
xref: PTHR24068:SF43
xref: uniprot Q9QZU9 520
organism: Mus musculus

uniprot O88761 87
type: UnificationXref
id: O88761
db: uniprot

Ubiquitin-conjugating enzyme E2 S
type: ProteinReference
xref: uniprot Q921J4 503
organism: Mus musculus

uniprot P51668 412
type: UnificationXref
id: P51668
db: uniprot

ncbitaxon 3702 70
type: UnificationXref
id: 3702
db: ncbitaxon

Predicted protein
type: ProteinReference
xref: uniprot A9SDW9 300
organism: Physcomitrella patens

ncbitaxon 3055 21
type: UnificationXref
id: 3055
db: ncbitaxon

uniprot H2R294 553
type: UnificationXref
id: H2R294
db: uniprot

uniprot P61085 245
type: UnificationXref
id: P61085
db: uniprot

uniprot Q19360 568
type: UnificationXref
id: Q19360
db: uniprot

UBE2G1 isoform 4
type: ProteinReference
xref: uniprot K7CGF3 382
organism: Pan troglodytes

uniprot F6W7B6 343
type: UnificationXref
id: F6W7B6
db: uniprot

UBE3A protein
type: ProteinReference
xref: uniprot A4IFN7 186
organism: Bos taurus

Ubiquitin-conjugating enzyme E2 E2
type: ProteinReference
xref: uniprot F7H5G8 362
organism: Macaca mulatta

Neurospora crassa
type: BioSource
xref: ncbitaxon 367110 110

uniprot H2Q7D5 370
type: UnificationXref
id: H2Q7D5
db: uniprot

STATE_TRANSITION_LEFT__Complex__ubiquitin_E1_-RIGHT__E1-_AMP-_r10
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r10 617
participant stoichiometry: PARTICIPANT STOICHIOMETRY r10 616
participant stoichiometry: PARTICIPANT STOICHIOMETRY r10 615
left: Complex (ubiquitin/E1)
interaction type: STATE_TRANSITION
right: E1
right: AMP

Ubiquitin conjugating enzyme E2 V2
type: ProteinReference
xref: uniprot A0A1L1RZV0 279
organism: Gallus gallus

uniprot Q5B9M0 464
type: UnificationXref
id: Q5B9M0
db: uniprot

26S proteasome non-ATPase regulatory subunit 2 homolog
type: ProteinReference
xref: uniprot B9FQQ6 34
organism: Oryza sativa

Uncharacterized protein
type: ProteinReference
xref: uniprot F7CC81 351
organism: Monodelphis domestica

Lysine Protein target s4 a4 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY Lysine
feature location: Lysine Protein target s4 a4 rs1 Lysine
comment: MODIFICATION_RESIDUE_NAME=Lysine
comment: MODIFICATION_RESIDUE_SIDE=none
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_ANGLE=0.7454189465414205

Uncharacterized protein
type: ProteinReference
xref: uniprot Q0UZR5 443
organism: Phaeosphaeria nodorum

26S protease regulatory subunit 4, putative, expressed
type: ProteinReference
xref: uniprot Q8W422 143
organism: Oryza sativa

Uncharacterized protein
type: ProteinReference
xref: uniprot E2RKT9 320
xref: PTHR24068:SF67
organism: Canis lupus familiaris

26S proteasome regulatory particle non-ATPase subunit12
type: ProteinReference
xref: uniprot Q8W423 144
organism: Oryza sativa

uniprot A8XMM5 295
type: UnificationXref
id: A8XMM5
db: uniprot

E3 ubiquitin-protein ligase
type: ProteinReference
xref: PTHR11254:SF293
xref: uniprot A0A0G2K612 175
organism: Rattus norvegicus

uniprot A9TJC3 30
type: UnificationXref
id: A9TJC3
db: uniprot

uniprot F7FCV2 549
type: UnificationXref
id: F7FCV2
db: uniprot

uniprot Q5SNC0 124
type: UnificationXref
id: Q5SNC0
db: uniprot

Ubiquitin-protein ligase E3B
type: ProteinReference
xref: uniprot Q9ES34 266
organism: Mus musculus

uniprot A0A1L1RJI2 179
type: UnificationXref
id: A0A1L1RJI2
db: uniprot

uniprot Q6DDC8 470
type: UnificationXref
id: Q6DDC8
db: uniprot

ncbitaxon 36329 84
type: UnificationXref
id: 36329
db: ncbitaxon

Ubiquitin-conjugating enzyme E2 20
type: ProteinReference
xref: uniprot Q8L7T3 494
organism: Arabidopsis thaliana

26S proteasome regulatory subunit 7 homolog A
type: ProteinReference
xref: uniprot Q9SSB5 165
organism: Arabidopsis thaliana

Ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome)
type: ProteinReference
xref: uniprot F6U235 212
organism: Xenopus tropicalis

uniprot A0A3Q1MNS5 285
type: UnificationXref
id: A0A3Q1MNS5
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F1NR71 46
organism: Gallus gallus

Ubiquitin conjugating enzyme E2 B
type: ProteinReference
xref: uniprot E2RRR7 322
organism: Canis lupus familiaris

Ubiquitin conjugating enzyme E2 V2
type: ProteinReference
xref: uniprot F7CL20 352
organism: Ornithorhynchus anatinus

uniprot Q94CD5 576
type: UnificationXref
id: Q94CD5
db: uniprot

uniprot F6R1X3 50
type: UnificationXref
id: F6R1X3
db: uniprot

26S proteasome non-ATPase regulatory subunit 1
type: ProteinReference
xref: uniprot G2HJQ1 61
organism: Pan troglodytes

uniprot O94609 557
type: UnificationXref
id: O94609
db: uniprot

uniprot E2RRR7 322
type: UnificationXref
id: E2RRR7
db: uniprot

uniprot P51965 413
type: UnificationXref
id: P51965
db: uniprot

Pan troglodytes
type: BioSource
xref: ncbitaxon 9598 4

SH E2 s14 a19 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY SH
feature location: SH E2 s14 a19 rs1 SH
modification type: MODIFICATION FEATURE ubiquitinated
comment: MODIFICATION_RESIDUE_SIDE=outside
comment: MODIFICATION_RESIDUE_ANGLE=0.78837880158871
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=SH

uniprot P50524 98
type: UnificationXref
id: P50524
db: uniprot

Os03g0214600 protein
type: ProteinReference
xref: uniprot Q10Q05 106
organism: Oryza sativa

PANTHER Pathway P00060 1
type: UnificationXref
id: P00060
db: PANTHER Pathway

PARTICIPANT STOICHIOMETRY r12 632
type: Stoichiometry
physical entity: Protein target
stoichiometric coefficient: 1.0

uniprot F6VCY8 340
type: UnificationXref
id: F6VCY8
db: uniprot

PARTICIPANT STOICHIOMETRY r12 631
type: Stoichiometry
physical entity: E2
stoichiometric coefficient: 1.0

RCG32249
type: ProteinReference
xref: uniprot D3ZUW6 312
organism: Rattus norvegicus

PARTICIPANT STOICHIOMETRY r12 630
type: Stoichiometry
physical entity: Protein target
stoichiometric coefficient: 1.0

uniprot Q69Q32 126
type: UnificationXref
id: Q69Q32
db: uniprot

Ubiquitin-like modifier-activating enzyme 1
type: ProteinReference
xref: uniprot Q02053 249
organism: Mus musculus

UBA6 isoform 1
type: ProteinReference
xref: uniprot H2QPJ4 552
organism: Pan troglodytes

uniprot Q4V8H7 254
type: UnificationXref
id: Q4V8H7
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot Q5ZL59 466
organism: Gallus gallus

ncbitaxon 3218 10
type: UnificationXref
id: 3218
db: ncbitaxon

Uncharacterized protein
type: ProteinReference
xref: uniprot F7G2B2 359
organism: Monodelphis domestica

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A3Q1MJI4 531
organism: Bos taurus

uniprot F7H5G8 362
type: UnificationXref
id: F7H5G8
db: uniprot

NEDD4-like E3 ubiquitin-protein ligase WWP1
type: ProteinReference
xref: uniprot Q9H0M0 267
organism: Homo sapiens

uniprot A0A2I3TGY5 182
type: UnificationXref
id: A0A2I3TGY5
db: uniprot

26S proteasome regulatory subunit 6B homolog
type: ProteinReference
xref: uniprot P34123 599
organism: Dictyostelium discoideum

Probable ubiquitin-conjugating enzyme E2 7
type: ProteinReference
xref: uniprot P34477 401
organism: Caenorhabditis elegans

Proteasome regulatory particle subunit Rpt3, putative (AFU_orthologue AFUA_3G11390)
type: ProteinReference
xref: uniprot C8VJ79 590
organism: Emericella nidulans

uniprot O14933 387
type: UnificationXref
id: O14933
db: uniprot

UBE3A isoform 14
type: ProteinReference
xref: uniprot A0A2I3SJZ1 181
organism: Pan troglodytes

Ubiquitin proteasome pathway
type: Pathway
pathway component: STATE_TRANSITION_LEFT__E2-_Protein_target-RIGHT__E2-_Protein_target-_r12
pathway component: STATE_TRANSITION_LEFT__E2-_E1-RIGHT__E1-_E2-_r11
pathway component: STATE_TRANSITION_LEFT__Complex__ubiquitin_E1_-RIGHT__E1-_AMP-_r10
pathway component: STATE_TRANSITION_LEFT__E1-_ubiquitin-_ATP-RIGHT__Complex__ubiquitin_E1_-_PPi-_r9
pathway component: STATE_TRANSITION_LEFT__ATP-_Protein_target-RIGHT__ADP-_ubiquitin-_a24_degraded-_Pi-_r7
xref: PANTHER Pathway P00060 1
comment: MODEL_NOTES=Panther Pathway: P00060 Various proteins are covalently modified on lysine side chain residues with the 76 amino acid peptide ubiquitin. This can lead to targeting for degradation by the proteasome machinery or can merely be the basis for regulatory control such as activation of receptor endocytosis. Medline=14685250 Medline=14723977 Medline=14744430 PMID: 14685250 PMID: 14723977 PMID: 14744430

Uncharacterized protein
type: ProteinReference
xref: uniprot C3ZGJ2 309
organism: Branchiostoma floridae

uniprot O77397 393
type: UnificationXref
id: O77397
db: uniprot

uniprot F1PQT6 207
type: UnificationXref
id: F1PQT6
db: uniprot

26S proteasome non-ATPase regulatory subunit 7 homolog A
type: ProteinReference
xref: uniprot O24412 73
xref: PTHR10540:SF7
organism: Arabidopsis thaliana

26S proteasome non-ATPase regulatory subunit 13 homolog A
type: ProteinReference
xref: uniprot Q8RWF0 138
organism: Arabidopsis thaliana

Ubiquitin-protein ligase E3C
type: ProteinReference
xref: uniprot Q15386 251
organism: Homo sapiens

P-loop containing nucleoside triphosphate hydrolases superfamily protein
type: ProteinReference
xref: uniprot Q9LIM2 154
organism: Arabidopsis thaliana

Proteasome 26S subunit, non-ATPase 4
type: ProteinReference
xref: PTHR10223:SF0
xref: uniprot A0A452DI44 13
organism: Bos taurus

E3 ubiquitin-protein ligase
type: ProteinReference
xref: PTHR11254:SF293
xref: uniprot F1PQT6 207
organism: Canis lupus familiaris

uniprot Q8TBC4 574
type: UnificationXref
id: Q8TBC4
db: uniprot

uniprot A7E947 15
type: UnificationXref
id: A7E947
db: uniprot

SAE1 isoform 9
type: ProteinReference
xref: uniprot G2HJS6 550
organism: Pan troglodytes

uniprot O74201 389
type: UnificationXref
id: O74201
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F7BMV0 545
organism: Monodelphis domestica

uniprot A0A2I3SAT6 281
type: UnificationXref
id: A0A2I3SAT6
db: uniprot

26S proteasome s16 sa1 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: 26S proteasome
stoichiometric coefficient: 1.0

uniprot F7CC81 351
type: UnificationXref
id: F7CC81
db: uniprot

Ubiquitin-conjugating enzyme E2 D2
type: ProteinReference
xref: uniprot P62838 432
organism: Mus musculus

Ubiquitin-conjugating enzyme E2 D2
type: ProteinReference
xref: uniprot P62837 431
organism: Homo sapiens

Uncharacterized protein
type: ProteinReference
xref: uniprot A7E947 15
organism: Sclerotinia sclerotiorum

Ubiquitin-conjugating enzyme E2 E3
type: ProteinReference
xref: uniprot A0A1D5QJN8 273
organism: Macaca mulatta

uniprot Q86IZ3 492
type: UnificationXref
id: Q86IZ3
db: uniprot

Ubiquitin carboxyl-terminal hydrolase
type: ProteinReference
xref: uniprot Q1K7Z3 111
organism: Neurospora crassa

uniprot Q9LT08 155
type: UnificationXref
id: Q9LT08
db: uniprot

uniprot Q0DK90 440
type: UnificationXref
id: Q0DK90
db: uniprot

Ubiquitin-conjugating enzyme E2 29
type: ProteinReference
xref: uniprot Q9SLE4 522
organism: Arabidopsis thaliana

ncbitaxon 6669 44
type: UnificationXref
id: 6669
db: ncbitaxon

uniprot F6SU17 336
type: UnificationXref
id: F6SU17
db: uniprot

uniprot Q9UTG2 270
type: UnificationXref
id: Q9UTG2
db: uniprot

uniprot A7F3F7 588
type: UnificationXref
id: A7F3F7
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot C3ZMI7 310
organism: Branchiostoma floridae

uniprot Q3ZBD0 113
type: UnificationXref
id: Q3ZBD0
db: uniprot

uniprot F6RKN5 210
type: UnificationXref
id: F6RKN5
db: uniprot

Ubiquitin-conjugating enzyme E2 E2
type: ProteinReference
xref: uniprot Q96LR5 506
organism: Homo sapiens

uniprot P15731 395
type: UnificationXref
id: P15731
db: uniprot

26S proteasome non-ATPase regulatory subunit 2
type: ProteinReference
xref: uniprot Q4FZT9 114
organism: Rattus norvegicus

uniprot O48844 80
type: UnificationXref
id: O48844
db: uniprot

uniprot P32496 91
type: UnificationXref
id: P32496
db: uniprot

E3 ubiquitin-protein ligase Mdm2
type: ProteinReference
xref: uniprot H9FUJ1 228
xref: PTHR13844:SF15
organism: Macaca mulatta

Activator of SUMO 1
type: ProteinReference
xref: uniprot Q7KSM5 572
organism: Drosophila melanogaster

uniprot F6Z480 346
type: UnificationXref
id: F6Z480
db: uniprot

Ubiquitin-conjugating enzyme E2 B
type: ProteinReference
xref: uniprot Q32P99 454
organism: Bos taurus

uniprot A7F0Q4 289
type: UnificationXref
id: A7F0Q4
db: uniprot

Predicted protein
type: ProteinReference
xref: uniprot A9RXP4 297
organism: Physcomitrella patens

uniprot F7EVY1 354
type: UnificationXref
id: F7EVY1
db: uniprot

PARTICIPANT STOICHIOMETRY r12 629
type: Stoichiometry
physical entity: E2
stoichiometric coefficient: 1.0

26S proteasome non-ATPase regulatory subunit 13
type: ProteinReference
xref: uniprot Q9UNM6 167
xref: PTHR10539:SF0
organism: Homo sapiens

Uncharacterized protein
type: ProteinReference
xref: uniprot F6ZC17 347
xref: PTHR24068:SF67
organism: Macaca mulatta

uniprot Q9FI61 511
type: UnificationXref
id: Q9FI61
db: uniprot

Ubiquitin-conjugating enzyme E2 2
type: ProteinReference
xref: uniprot Q96UP5 507
organism: Emericella nidulans

UBE2G2 isoform 1
type: ProteinReference
xref: uniprot H2QL51 371
organism: Pan troglodytes

Ubiquitin-like modifier-activating enzyme 6
type: ProteinReference
xref: uniprot H9FWM4 554
organism: Macaca mulatta

Uncharacterized protein
type: ProteinReference
xref: uniprot F1ME38 538
organism: Bos taurus

uniprot O82143 85
type: UnificationXref
id: O82143
db: uniprot

uniprot P52490 418
type: UnificationXref
id: P52490
db: uniprot

uniprot H2R545 226
type: UnificationXref
id: H2R545
db: uniprot

uniprot Q9UBE0 582
type: UnificationXref
id: Q9UBE0
db: uniprot

uniprot Q3ZCF7 457
type: UnificationXref
id: Q3ZCF7
db: uniprot

uniprot Q96UP5 507
type: UnificationXref
id: Q96UP5
db: uniprot

uniprot K7BPT6 381
type: UnificationXref
id: K7BPT6
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A2K1JHJ3 9
organism: Physcomitrella patens

Uncharacterized protein
type: ProteinReference
xref: uniprot H2Q7D5 370
xref: PTHR24068:SF67
organism: Pan troglodytes

E3 ubiquitin-protein ligase Itchy
type: ProteinReference
xref: uniprot Q8C863 261
organism: Mus musculus

uniprot Q9WVJ2 170
type: UnificationXref
id: Q9WVJ2
db: uniprot

uniprot P62253 428
type: UnificationXref
id: P62253
db: uniprot

ncbitaxon 227321 119
type: UnificationXref
id: 227321
db: ncbitaxon

Predicted protein
type: ProteinReference
xref: uniprot A9T1P2 29
organism: Physcomitrella patens

NEDD4-like E3 ubiquitin-protein ligase WWP2
type: ProteinReference
xref: uniprot O00308 233
organism: Homo sapiens

uniprot F6RWK8 333
type: UnificationXref
id: F6RWK8
db: uniprot

uniprot A9SCM3 299
type: UnificationXref
id: A9SCM3
db: uniprot

uniprot Q8RWF0 138
type: UnificationXref
id: Q8RWF0
db: uniprot

uniprot O95352 558
type: UnificationXref
id: O95352
db: uniprot

Three prime repair exonuclease 2
type: ProteinReference
xref: uniprot Q9BQ50 150
organism: Homo sapiens

uniprot B9FQQ6 34
type: UnificationXref
id: B9FQQ6
db: uniprot

26S proteasome regulatory subunit T3
type: ProteinReference
xref: uniprot Q7PGR3 605
organism: Anopheles gambiae

uniprot Q641Y5 570
type: UnificationXref
id: Q641Y5
db: uniprot

E3 ubiquitin-protein ligase
type: ProteinReference
xref: PTHR11254:SF293
xref: uniprot F1NFN4 203
organism: Gallus gallus

uniprot O65041 556
type: UnificationXref
id: O65041
db: uniprot

uniprot A0JM78 286
type: UnificationXref
id: A0JM78
db: uniprot

Ubiquitin-like modifier-activating enzyme ATG7
type: ProteinReference
xref: uniprot O95352 558
organism: Homo sapiens

PTHR10410:SF27
type: RelationshipXref
id: PTHR10410:SF27
db: PANTHER Family
relationship type: By Homology

ncbitaxon 6945 307
type: UnificationXref
id: 6945
db: ncbitaxon

Uncharacterized protein
type: ProteinReference
xref: uniprot F7GU37 361
organism: Macaca mulatta

ncbitaxon 8364 53
type: UnificationXref
id: 8364
db: ncbitaxon

uniprot Q7GCH3 131
type: UnificationXref
id: Q7GCH3
db: uniprot

Macaca mulatta
type: BioSource
xref: ncbitaxon 9544 51

uniprot O35593 76
type: UnificationXref
id: O35593
db: uniprot

uniprot P52486 416
type: UnificationXref
id: P52486
db: uniprot

uniprot F7HIL8 596
type: UnificationXref
id: F7HIL8
db: uniprot

Ubiquitin-conjugating enzyme E2 V2
type: ProteinReference
xref: uniprot Q28G19 450
organism: Xenopus tropicalis

Autophagy related 7
type: ProteinReference
xref: uniprot F1PI66 539
organism: Canis lupus familiaris

Uncharacterized protein
type: ProteinReference
xref: uniprot F6QW29 332
organism: Monodelphis domestica

Ubiquitin-conjugating enzyme
type: ProteinReference
xref: uniprot Q9W6F3 526
organism: Gallus gallus

uniprot A0A2I3TPZ7 8
type: UnificationXref
id: A0A2I3TPZ7
db: uniprot

uniprot Q8LGF7 495
type: UnificationXref
id: Q8LGF7
db: uniprot

uniprot F7EP98 547
type: UnificationXref
id: F7EP98
db: uniprot

Physcomitrella patens
type: BioSource
xref: ncbitaxon 3218 10

Ubiquitin-conjugating enzyme E2 4
type: ProteinReference
xref: uniprot P46595 410
organism: Schizosaccharomyces pombe

uniprot P63149 435
type: UnificationXref
id: P63149
db: uniprot

uniprot P62255 430
type: UnificationXref
id: P62255
db: uniprot

Ubiquitin-conjugating enzyme E2B (RAD6 homolog)
type: ProteinReference
xref: uniprot Q6DGE1 471
organism: Danio rerio

uniprot O04202 71
type: UnificationXref
id: O04202
db: uniprot

Methanosarcina acetivorans
type: BioSource
xref: ncbitaxon 188937 140

Uncharacterized protein
type: ProteinReference
xref: uniprot E9FRE8 323
organism: Daphnia pulex

Ubiquitin-conjugating enzyme E2 2
type: ProteinReference
xref: uniprot O74201 389
organism: Candida albicans

uniprot A0A2I3RTF4 3
type: UnificationXref
id: A0A2I3RTF4
db: uniprot

Ubiquitin-conjugating enzyme E2 G2
type: ProteinReference
xref: uniprot Q28I82 451
organism: Xenopus tropicalis

SUMO-activating enzyme subunit 2
type: ProteinReference
xref: uniprot Q9SJT1 581
organism: Arabidopsis thaliana

E3
type: Protein
entity reference: E3
cellular location: cytosol
comment: SPECIES_TYPE=PROTEIN

Ubiquitin like modifier activating enzyme 3
type: ProteinReference
xref: uniprot F7EP98 547
organism: Ornithorhynchus anatinus

uniprot P61079 424
type: UnificationXref
id: P61079
db: uniprot

26S proteasome regulatory complex subunit p39A
type: ProteinReference
xref: uniprot Q7KMP8 132
xref: PTHR10539:SF0
organism: Drosophila melanogaster

Predicted protein
type: ProteinReference
xref: uniprot A9REE1 22
organism: Physcomitrella patens

PTHR10678:SF2
type: RelationshipXref
id: PTHR10678:SF2
db: PANTHER Family
relationship type: By Homology

uniprot B0BN93 32
type: UnificationXref
id: B0BN93
db: uniprot

uniprot P22314 238
type: UnificationXref
id: P22314
db: uniprot

Os01g0925800 protein
type: ProteinReference
xref: uniprot Q8S1Y5 496
organism: Oryza sativa

Uncharacterized protein
type: ProteinReference
xref: uniprot F7GIS4 360
organism: Macaca mulatta

NEDD8-activating enzyme E1 catalytic subunit
type: ProteinReference
xref: uniprot Q8C878 573
organism: Mus musculus

uniprot P38764 93
type: UnificationXref
id: P38764
db: uniprot

uniprot P52483 415
type: UnificationXref
id: P52483
db: uniprot

uniprot O00762 385
type: UnificationXref
id: O00762
db: uniprot

UBA7 isoform 1
type: ProteinReference
xref: uniprot K7BL13 231
organism: Pan troglodytes

Predicted protein
type: ProteinReference
xref: uniprot A9SRU1 26
organism: Physcomitrella patens

PTHR13844:SF15
type: RelationshipXref
id: PTHR13844:SF15
db: PANTHER Family
relationship type: By Homology

UBE2A isoform 1
type: ProteinReference
xref: uniprot H2QZ18 373
organism: Pan troglodytes

uniprot Q80U95 259
type: UnificationXref
id: Q80U95
db: uniprot

Ubiquitin-conjugating enzyme E2 2
type: ProteinReference
xref: uniprot P23566 398
organism: Schizosaccharomyces pombe

uniprot F7C462 349
type: UnificationXref
id: F7C462
db: uniprot

uniprot P46595 410
type: UnificationXref
id: P46595
db: uniprot

Ubiquitin conjugating enzyme E2 K
type: ProteinReference
xref: uniprot F7AQ16 348
organism: Monodelphis domestica

Predicted protein
type: ProteinReference
xref: uniprot A9S5I6 25
organism: Physcomitrella patens

NEDD8-activating enzyme E1 catalytic subunit
type: ProteinReference
xref: uniprot Q09765 566
organism: Schizosaccharomyces pombe

uniprot Q4V9I8 461
type: UnificationXref
id: Q4V9I8
db: uniprot

uniprot P22515 560
type: UnificationXref
id: P22515
db: uniprot

uniprot Q92462 262
type: UnificationXref
id: Q92462
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F6Y9A7 595
organism: Monodelphis domestica

uniprot Q69X47 127
type: UnificationXref
id: Q69X47
db: uniprot

Ubiquitin-conjugating enzyme E2 E1
type: ProteinReference
xref: uniprot P51965 413
organism: Homo sapiens

SH E1 s12 a17 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY SH
feature location: SH E1 s12 a17 rs1 SH
modification type: MODIFICATION FEATURE ubiquitinated
comment: MODIFICATION_RESIDUE_SIDE=outside
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=SH
comment: MODIFICATION_RESIDUE_ANGLE=0.715273327379819

ncbitaxon 284812 78
type: UnificationXref
id: 284812
db: ncbitaxon

uniprot H9FWM4 554
type: UnificationXref
id: H9FWM4
db: uniprot

Ubiquitin protein ligase, putative
type: ProteinReference
xref: uniprot B7Q0U7 308
organism: Ixodes scapularis

E3 ubiquitin-protein ligase pub3
type: ProteinReference
xref: uniprot O14326 236
organism: Schizosaccharomyces pombe

STATE_TRANSITION
type: RelationshipTypeVocabulary

uniprot P41226 240
type: UnificationXref
id: P41226
db: uniprot

Ubiquitin-conjugating enzyme E2 A
type: ProteinReference
xref: uniprot Q9Z255 529
organism: Mus musculus

Chlamydomonas reinhardtii
type: BioSource
xref: ncbitaxon 3055 21

uniprot F6PLU9 209
type: UnificationXref
id: F6PLU9
db: uniprot

26S proteasome regulatory subunit 7A
type: ProteinReference
xref: uniprot P0DKJ9 90
organism: Oryza sativa

26S proteasome regulatory subunit RPN10
type: ProteinReference
xref: uniprot P38886 94
organism: Saccharomyces cerevisiae

PTHR48177:SF1
type: RelationshipXref
id: PTHR48177:SF1
db: PANTHER Family
relationship type: By Homology

uniprot F6ZC17 347
type: UnificationXref
id: F6ZC17
db: uniprot

uniprot A0A1D5QWZ3 276
type: UnificationXref
id: A0A1D5QWZ3
db: uniprot

uniprot F7HMX1 60
type: UnificationXref
id: F7HMX1
db: uniprot

PSMD7 isoform 1
type: ProteinReference
xref: uniprot H2QBI1 62
xref: PTHR10540:SF12
organism: Pan troglodytes

uniprot A0A452DI44 13
type: UnificationXref
id: A0A452DI44
db: uniprot

uniprot F6TXY0 339
type: UnificationXref
id: F6TXY0
db: uniprot

uniprot P40985 239
type: UnificationXref
id: P40985
db: uniprot

Ubiquitin conjugating enzyme E2 S
type: ProteinReference
xref: uniprot J9PAH6 380
organism: Canis lupus familiaris

Proteasome 26S subunit, ATPase 4
type: ProteinReference
xref: uniprot A0A2I3TDC1 587
organism: Pan troglodytes

uniprot E2RCP9 42
type: UnificationXref
id: E2RCP9
db: uniprot

uniprot E2RBA6 193
type: UnificationXref
id: E2RBA6
db: uniprot

uniprot Q9SVD7 523
type: UnificationXref
id: Q9SVD7
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F7HBX8 363
organism: Macaca mulatta

P01490
type: UnificationXref
id: P01490
db: PANTHER Pathway Component

P01491
type: UnificationXref
id: P01491
db: PANTHER Pathway Component

Ubiquitin-conjugating enzyme E2 D2B
type: ProteinReference
xref: uniprot P70711 438
organism: Rattus norvegicus

P01494
type: UnificationXref
id: P01494
db: PANTHER Pathway Component

P01492
type: UnificationXref
id: P01492
db: PANTHER Pathway Component

UBA (Human ubiquitin) related
type: ProteinReference
xref: uniprot Q27481 569
organism: Caenorhabditis elegans

uniprot P61088 426
type: UnificationXref
id: P61088
db: uniprot

Caenorhabditis briggsae
type: BioSource
xref: ncbitaxon 6238 293

E1
type: Protein
entity reference: E1
feature: SH E1 s1 a1 rs1
cellular location: cytosol
comment: SPECIES_TYPE=PROTEIN

Ubiquitin like modifier activating enzyme 1
type: ProteinReference
xref: uniprot E2RGH5 194
organism: Canis lupus familiaris

uniprot Q8GYA6 137
type: UnificationXref
id: Q8GYA6
db: uniprot

Caenorhabditis elegans
type: BioSource
xref: ncbitaxon 6239 402

P01489
type: UnificationXref
id: P01489
db: PANTHER Pathway Component

Os07g0166800 protein
type: ProteinReference
xref: uniprot Q7XIC8 487
organism: Oryza sativa

E3 ubiquitin-protein ligase
type: ProteinReference
xref: uniprot A0A0G2K9T1 176
organism: Rattus norvegicus

uniprot A3KMV5 185
type: UnificationXref
id: A3KMV5
db: uniprot

uniprot Q8C863 261
type: UnificationXref
id: Q8C863
db: uniprot

Pristionchus pacificus
type: BioSource
xref: ncbitaxon 54126 376

uniprot P25867 400
type: UnificationXref
id: P25867
db: uniprot

Ubiquitin-activating enzyme E1 1
type: ProteinReference
xref: uniprot P22515 560
organism: Saccharomyces cerevisiae

ATP
type: SmallMolecule
cellular location: cytosol
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot A0A1D5QWJ2 275
type: UnificationXref
id: A0A1D5QWJ2
db: uniprot

uniprot O00103 384
type: UnificationXref
id: O00103
db: uniprot

uniprot Q27481 569
type: UnificationXref
id: Q27481
db: uniprot

26S proteasome regulatory subunit rpn8
type: ProteinReference
xref: uniprot O74440 81
xref: PTHR10540:SF7
organism: Schizosaccharomyces pombe

uniprot P52488 562
type: UnificationXref
id: P52488
db: uniprot

Ubiquitin-conjugating enzyme E2 T
type: ProteinReference
xref: uniprot Q9NPD8 517
organism: Homo sapiens

UBE3C isoform 1
type: ProteinReference
xref: uniprot H2QVP1 224
organism: Pan troglodytes

SUMO-activating enzyme subunit 2
type: ProteinReference
xref: uniprot A4FV12 534
organism: Bos taurus

Ubiquitin-conjugating enzyme E2 G2
type: ProteinReference
xref: uniprot P60605 421
organism: Mus musculus

Ubiquitin-conjugating enzyme E2 G2
type: ProteinReference
xref: uniprot P60604 420
organism: Homo sapiens

uniprot Q9UNM6 167
type: UnificationXref
id: Q9UNM6
db: uniprot

Ubiquitin-conjugating enzyme E2 C
type: ProteinReference
xref: uniprot Q32PA5 455
organism: Bos taurus

uniprot E2R6W9 192
type: UnificationXref
id: E2R6W9
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F7HH32 364
organism: Macaca mulatta

uniprot F6Z075 345
type: UnificationXref
id: F6Z075
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F1N703 202
organism: Bos taurus

SH E1 s1 a1 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY SH
feature location: SH E1 s1 a1 rs1 SH
comment: MODIFICATION_RESIDUE_SIDE=outside
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=SH
comment: MODIFICATION_RESIDUE_ANGLE=0.715273327379819

Ubiquitin-conjugating enzyme E2 15
type: ProteinReference
xref: uniprot Q9Y818 528
organism: Schizosaccharomyces pombe

Proteasome 26S subunit, ATPase 4
type: ProteinReference
xref: uniprot E2RH48 592
organism: Canis lupus familiaris

UBA3 isoform 2
type: ProteinReference
xref: uniprot H2R294 553
organism: Pan troglodytes

Ubiquitin/ISG15-conjugating enzyme E2 L6
type: ProteinReference
xref: PTHR24068:SF43
xref: uniprot O14933 387
organism: Homo sapiens

uniprot B7PKN3 306
type: UnificationXref
id: B7PKN3
db: uniprot

26S proteasome regulatory subunit
type: ProteinReference
xref: uniprot A8IV67 20
organism: Chlamydomonas reinhardtii

Ubiquitin-conjugating enzyme E2 C
type: ProteinReference
xref: uniprot O00762 385
organism: Homo sapiens

26S proteasome regulatory subunit rpn-8
type: ProteinReference
xref: uniprot Q8WZY4 146
xref: PTHR10540:SF7
organism: Neurospora crassa

uniprot Q8C878 573
type: UnificationXref
id: Q8C878
db: uniprot

Ubiquitin-conjugating enzyme E2 pex4
type: ProteinReference
xref: uniprot Q86IZ3 492
organism: Dictyostelium discoideum

Ubiquitin conjugating enzyme E2 B
type: ProteinReference
xref: uniprot F6RWK8 333
organism: Ornithorhynchus anatinus

Ubiquitin-conjugating enzyme E2 A
type: ProteinReference
xref: uniprot P49459 411
organism: Homo sapiens

Sclerotinia sclerotiorum
type: BioSource
xref: ncbitaxon 665079 16

uniprot A0A0G2K9T1 176
type: UnificationXref
id: A0A0G2K9T1
db: uniprot

26S proteasome
type: ProteinReference
xref: P01489
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Ubiquitin proteasome pathway.PROTEIN.GENERIC.26S proteasome
comment: ENTITY_REFERENCE_NOTES=
member entity reference: 26S proteasome non-ATPase regulatory subunit 4
member entity reference: 26S proteasome non-ATPase regulatory subunit 7 homolog A
member entity reference: 26S proteasome regulatory complex subunit p39A
member entity reference: 26S proteasome regulatory subunit RPN1
member entity reference: Proteasome subunit beta type-5-A
member entity reference: 26S proteasome regulatory subunit 6A homolog A
member entity reference: Proteasome-activating nucleotidase
member entity reference: Predicted protein
member entity reference: Uncharacterized protein
member entity reference: Proteasome 26S subunit, non-ATPase 7
member entity reference: 26S proteasome non-ATPase regulatory subunit 14
member entity reference: Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14
member entity reference: 26S proteasome non-ATPase regulatory subunit 1
member entity reference: Probable 26S proteasome regulatory subunit rpn3
member entity reference: 26S proteasome non-ATPase regulatory subunit 2 homolog
member entity reference: 26S proteasome regulatory subunit rpn12
member entity reference: 26S proteasome regulatory subunit
member entity reference: 26S proteasome regulatory subunit RPN12,putative
member entity reference: 26S proteasome non-ATPase regulatory subunit 1 homolog B
member entity reference: 26S proteasome regulatory subunit rpn10
member entity reference: 26S proteasome regulatory particle triple-A ATPase subunit4
member entity reference: 26S proteasome non-ATPase regulatory subunit 2
member entity reference: 26S proteasome non-ATPase regulatory subunit 13 homolog A
member entity reference: 26S proteasome regulatory subunit 4 homolog
member entity reference: 26S proteasome regulatory subunit rpn-8
member entity reference: 26S proteasome regulatory subunit 4 homolog B
member entity reference: 26S proteasome regulatory subunit rpn8
member entity reference: Probable 26S proteasome regulatory subunit rpn6
member entity reference: Os01g0511300 protein
member entity reference: Probable 26S proteasome regulatory subunit rpn7
member entity reference: 26S proteasome non-ATPase regulatory subunit 2 homolog A
member entity reference: 26S proteasome regulatory particle non-ATPase subunit11
member entity reference: Proteasome 26S subunit, non-ATPase 4
member entity reference: 26S proteasome non-ATPase regulatory subunit 7
member entity reference: 26S protease regulatory subunit 4, putative, expressed
member entity reference: Putative proteasome regulatory non-ATP-ase subunit
member entity reference: 26S proteasome regulatory subunit 7A
member entity reference: 26S proteasome non-ATPase regulatory subunit 11
member entity reference: Antisecretory factor
member entity reference: 26S proteasome regulatory subunit 10B homolog A
member entity reference: 26S proteasome regulatory particle triple-A ATPase subunit6
member entity reference: PSMD14 isoform 1
member entity reference: 26S protease regulatory subunit 7
member entity reference: 26S proteasome non-ATPase regulatory subunit 13 homolog B
member entity reference: 26S proteasome regulatory subunit 4 homolog A
member entity reference: Probable 26S proteasome regulatory subunit p27
member entity reference: Three prime repair exonuclease 2
member entity reference: 26S proteasome regulatory subunit T4
member entity reference: Os06g0607800 protein
member entity reference: 26S proteasome regulatory subunit 6A homolog

uniprot P68036 436
type: UnificationXref
id: P68036
db: uniprot

uniprot O94393 88
type: UnificationXref
id: O94393
db: uniprot

uniprot Q5U300 255
type: UnificationXref
id: Q5U300
db: uniprot

uniprot A0A2I3TDC1 587
type: UnificationXref
id: A0A2I3TDC1
db: uniprot

uniprot A0A2K1JHJ3 9
type: UnificationXref
id: A0A2K1JHJ3
db: uniprot

SH E2 s2 a2 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY SH
feature location: SH E2 s2 a2 rs1 SH
comment: MODIFICATION_RESIDUE_SIDE=outside
comment: MODIFICATION_RESIDUE_ANGLE=0.78837880158871
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=SH

Uncharacterized protein
type: ProteinReference
xref: uniprot F1PDI6 326
organism: Canis lupus familiaris

uniprot Q9V3P6 168
type: UnificationXref
id: Q9V3P6
db: uniprot

uniprot P62254 429
type: UnificationXref
id: P62254
db: uniprot

Protein CBR-LET-70
type: ProteinReference
xref: uniprot A8X150 292
organism: Caenorhabditis briggsae

uniprot P55036 100
type: UnificationXref
id: P55036
db: uniprot

uniprot F1PYX5 327
type: UnificationXref
id: F1PYX5
db: uniprot

E3 ubiquitin-protein ligase Mdm2
type: ProteinReference
xref: PTHR13844:SF15
xref: uniprot Q00987 248
organism: Homo sapiens

Uncharacterized protein
type: ProteinReference
xref: uniprot F0ZYD1 593
organism: Dictyostelium purpureum

uniprot P56701 101
type: UnificationXref
id: P56701
db: uniprot

Branchiostoma floridae
type: BioSource
xref: ncbitaxon 7739 37

26S proteasome regulatory subunit 6B
type: ProteinReference
xref: uniprot Q63570 603
organism: Rattus norvegicus

uniprot Q6K5H9 128
type: UnificationXref
id: Q6K5H9
db: uniprot

uniprot F6QW29 332
type: UnificationXref
id: F6QW29
db: uniprot

ISS
type: EvidenceCodeVocabulary
xref: eco ECO:0000250 6

Ubiquitin conjugating enzyme E2 V2
type: ProteinReference
xref: uniprot A0A3Q1MNS5 285
organism: Bos taurus

uniprot B0R1D0 589
type: UnificationXref
id: B0R1D0
db: uniprot

Ubiquitin-conjugating enzyme E2-22 kDa
type: ProteinReference
xref: uniprot P52486 416
organism: Drosophila melanogaster

Ubiquitin-conjugating enzyme E2-18 kDa
type: ProteinReference
xref: uniprot P52487 417
xref: PTHR24068:SF116
organism: Drosophila melanogaster

uniprot P42750 242
type: UnificationXref
id: P42750
db: uniprot

ncbitaxon 185431 463
type: UnificationXref
id: 185431
db: ncbitaxon

Ubiquitin-conjugating enzyme E2 E1
type: ProteinReference
xref: uniprot P52482 414
organism: Mus musculus

Ubiquitin-conjugating enzyme E2 E3
type: ProteinReference
xref: uniprot P52483 415
organism: Mus musculus

Protein CBR-UBC-7
type: ProteinReference
xref: uniprot A8XA84 294
organism: Caenorhabditis briggsae

Uncharacterized protein
type: ProteinReference
xref: uniprot F6YMX6 544
organism: Macaca mulatta

uniprot E1C6N0 38
type: UnificationXref
id: E1C6N0
db: uniprot

26S proteasome non-ATPase regulatory subunit 2
type: ProteinReference
xref: uniprot F7EGU4 59
organism: Monodelphis domestica

uniprot A0A1D5QJN8 273
type: UnificationXref
id: A0A1D5QJN8
db: uniprot

uniprot B5DFI8 305
type: UnificationXref
id: B5DFI8
db: uniprot

ncbitaxon 284811 479
type: UnificationXref
id: 284811
db: ncbitaxon

Monodelphis domestica
type: BioSource
xref: ncbitaxon 13616 57

uniprot F7FZ60 355
type: UnificationXref
id: F7FZ60
db: uniprot

26S proteasome non-ATPase regulatory subunit 13
type: ProteinReference
xref: uniprot B0BN93 32
xref: PTHR10539:SF0
organism: Rattus norvegicus

26S proteasome non-ATPase regulatory subunit 14
type: ProteinReference
xref: PTHR10410:SF5
xref: uniprot O35593 76
organism: Mus musculus

E3 ubiquitin-protein ligase
type: ProteinReference
xref: uniprot F7DI62 217
organism: Monodelphis domestica

26S proteasome non-ATPase regulatory subunit 1
type: ProteinReference
xref: uniprot Q9V3P6 168
organism: Drosophila melanogaster

uniprot P34477 401
type: UnificationXref
id: P34477
db: uniprot

uniprot H9FZA7 377
type: UnificationXref
id: H9FZA7
db: uniprot

ncbitaxon 10090 75
type: UnificationXref
id: 10090
db: ncbitaxon

uniprot J9PAH6 380
type: UnificationXref
id: J9PAH6
db: uniprot

uniprot O74983 392
type: UnificationXref
id: O74983
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot E9H6I3 45
organism: Daphnia pulex

ncbitaxon 45351 19
type: UnificationXref
id: 45351
db: ncbitaxon

uniprot E2RGY5 318
type: UnificationXref
id: E2RGY5
db: uniprot

SUMO-activating enzyme subunit 1B-2
type: ProteinReference
xref: uniprot P0DI13 559
organism: Arabidopsis thaliana

uniprot Q8VY78 575
type: UnificationXref
id: Q8VY78
db: uniprot

uniprot D3ZUW6 312
type: UnificationXref
id: D3ZUW6
db: uniprot

uniprot Q02159 439
type: UnificationXref
id: Q02159
db: uniprot

uniprot A9JRT4 296
type: UnificationXref
id: A9JRT4
db: uniprot

Ubiquitin-conjugating enzyme E2 16
type: ProteinReference
xref: uniprot Q9P6I1 518
organism: Schizosaccharomyces pombe

26S proteasome regulatory subunit RPN12
type: ProteinReference
xref: uniprot P32496 91
organism: Saccharomyces cerevisiae

E3 ubiquitin-protein ligase
type: ProteinReference
xref: uniprot Q32PG0 253
organism: Bos taurus

uniprot A0A1D5QXE9 277
type: UnificationXref
id: A0A1D5QXE9
db: uniprot

19S proteasome
type: ProteinReference
xref: P01494
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES=
comment: ENTITY_REFERENCE_ID_DESC=Ubiquitin proteasome pathway.PROTEIN.GENERIC.19S proteasome
member entity reference: 26S proteasome regulatory subunit 6B homolog
member entity reference: Os02g0325100 protein
member entity reference: Proteasome regulatory ATPase subunit 3
member entity reference: 26S protease regulatory subunit 6B isoform 1
member entity reference: Uncharacterized protein
member entity reference: Novel protein (Zgc:63709)
member entity reference: 26S proteasome regulatory subunit 6B
member entity reference: Proteasome regulatory particle subunit Rpt3, putative (AFU_orthologue AFUA_3G11390)
member entity reference: Proteasome 26S subunit, ATPase 4
member entity reference: 26S proteasome regulatory subunit T3
member entity reference: Predicted protein
member entity reference: OTTXETP00000006803

Ubiquitin-conjugating enzyme E2 A
type: ProteinReference
xref: uniprot Q6GL05 472
organism: Xenopus tropicalis

26S proteasome non-ATPase regulatory subunit 7
type: ProteinReference
xref: uniprot Q3ZBD0 113
organism: Bos taurus

ncbitaxon 5664 116
type: UnificationXref
id: 5664
db: ncbitaxon

uniprot H2QBI1 62
type: UnificationXref
id: H2QBI1
db: uniprot

uniprot F6Q430 331
type: UnificationXref
id: F6Q430
db: uniprot

E3 ubiquitin-protein ligase SMURF2
type: ProteinReference
xref: PTHR11254:SF300
xref: uniprot Q9HAU4 268
organism: Homo sapiens

uniprot Q7PRY1 482
type: UnificationXref
id: Q7PRY1
db: uniprot

NEDD4-like E3 ubiquitin-protein ligase WWP2
type: ProteinReference
xref: uniprot Q9DBH0 265
organism: Mus musculus

ncbitaxon 321614 104
type: UnificationXref
id: 321614
db: ncbitaxon

ubiquitin
type: SmallMolecule
cellular location: cytosol
comment: SPECIES_TYPE=SIMPLE_MOLECULE

Ubiquitin-activating enzyme E1-like
type: ProteinReference
xref: uniprot P52488 562
organism: Saccharomyces cerevisiae

ncbitaxon 9913 14
type: UnificationXref
id: 9913
db: ncbitaxon

Ubiquitin-like modifier-activating enzyme 1 Y
type: ProteinReference
xref: uniprot P31254 561
organism: Mus musculus

uniprot Q6AXR9 469
type: UnificationXref
id: Q6AXR9
db: uniprot

ncbitaxon 665079 16
type: UnificationXref
id: 665079
db: ncbitaxon

uniprot F6TJ28 211
type: UnificationXref
id: F6TJ28
db: uniprot

uniprot Q42540 458
type: UnificationXref
id: Q42540
db: uniprot

PTHR10539:SF0
type: RelationshipXref
id: PTHR10539:SF0
db: PANTHER Family
relationship type: By Homology

uniprot F7A9B7 216
type: UnificationXref
id: F7A9B7
db: uniprot

SUMO-activating enzyme subunit 2
type: ProteinReference
xref: uniprot E2R837 537
organism: Canis lupus familiaris

uniprot Q8S920 498
type: UnificationXref
id: Q8S920
db: uniprot

ncbitaxon 54126 376
type: UnificationXref
id: 54126
db: ncbitaxon

Uncharacterized protein
type: ProteinReference
xref: uniprot F6YN15 214
organism: Monodelphis domestica

E2
type: Protein
entity reference: E2
feature: SH E2 s14 a19 rs1
cellular location: cytosol
comment: SPECIES_TYPE=PROTEIN

uniprot O77345 83
type: UnificationXref
id: O77345
db: uniprot

uniprot P33298 598
type: UnificationXref
id: P33298
db: uniprot

uniprot P46935 243
type: UnificationXref
id: P46935
db: uniprot

At2g32790
type: ProteinReference
xref: uniprot O48838 388
organism: Arabidopsis thaliana

uniprot Q96LR5 506
type: UnificationXref
id: Q96LR5
db: uniprot

26S proteasome non-ATPase regulatory subunit 1 homolog A
type: ProteinReference
xref: uniprot O48844 80
organism: Arabidopsis thaliana

E3 ubiquitin-protein ligase NEDD4
type: ProteinReference
xref: uniprot P46935 243
organism: Mus musculus

uniprot H2Q1X5 367
type: UnificationXref
id: H2Q1X5
db: uniprot

uniprot Q8VDM4 141
type: UnificationXref
id: Q8VDM4
db: uniprot

uniprot P61078 423
type: UnificationXref
id: P61078
db: uniprot

Ubiquitin-conjugating enzyme E2 13
type: ProteinReference
xref: uniprot P52490 418
organism: Saccharomyces cerevisiae

Predicted protein
type: ProteinReference
xref: uniprot A9SLJ8 301
organism: Physcomitrella patens

uniprot Q91W82 502
type: UnificationXref
id: Q91W82
db: uniprot

uniprot Q0UZR5 443
type: UnificationXref
id: Q0UZR5
db: uniprot

Ubiquitin-conjugating enzyme E2 2
type: ProteinReference
xref: uniprot P52493 419
organism: Neurospora crassa

uniprot F6YN15 214
type: UnificationXref
id: F6YN15
db: uniprot

uniprot W4YTT9 174
type: UnificationXref
id: W4YTT9
db: uniprot

uniprot E2R529 536
type: UnificationXref
id: E2R529
db: uniprot

26S proteasome regulatory particle chain RPT6-like protein
type: ProteinReference
xref: uniprot Q9FJC9 152
organism: Arabidopsis thaliana

ncbitaxon 9544 51
type: UnificationXref
id: 9544
db: ncbitaxon

Ubiquitin-conjugating enzyme E2 variant 2
type: ProteinReference
xref: uniprot Q9D2M8 509
organism: Mus musculus

uniprot E1C9E7 316
type: UnificationXref
id: E1C9E7
db: uniprot

26S proteasome non-ATPase regulatory subunit 1
type: ProteinReference
xref: uniprot O88761 87
organism: Rattus norvegicus

Ubiquitin-conjugating enzyme E2 C
type: ProteinReference
xref: uniprot F7CZ16 353
organism: Xenopus tropicalis

Uncharacterized protein
type: ProteinReference
xref: uniprot F7HMX1 60
xref: PTHR10410:SF5
organism: Macaca mulatta

Ubiquitin-like modifier-activating enzyme 1
type: ProteinReference
xref: uniprot P22314 238
organism: Homo sapiens

uniprot H2QG08 551
type: UnificationXref
id: H2QG08
db: uniprot

Arabidopsis thaliana
type: BioSource
xref: ncbitaxon 3702 70

uniprot Q5F418 122
type: UnificationXref
id: Q5F418
db: uniprot

uniprot J9P6R1 66
type: UnificationXref
id: J9P6R1
db: uniprot

Ubiquitin-conjugating enzyme E2 6
type: ProteinReference
xref: uniprot P42750 242
organism: Arabidopsis thaliana

Uncharacterized protein
type: ProteinReference
xref: uniprot Q5B963 118
organism: Emericella nidulans

uniprot Q63570 603
type: UnificationXref
id: Q63570
db: uniprot

Ubiquitin-conjugating enzyme E2 2
type: ProteinReference
xref: uniprot P42745 408
organism: Arabidopsis thaliana

uniprot P42743 407
type: UnificationXref
id: P42743
db: uniprot

Ubiquitin-conjugating enzyme 15
type: ProteinReference
xref: uniprot P42743 407
organism: Arabidopsis thaliana

E3 ubiquitin-protein ligase SMURF1
type: ProteinReference
xref: PTHR11254:SF293
xref: uniprot Q9CUN6 264
organism: Mus musculus

Ubiquitin-conjugating enzyme E2 4
type: ProteinReference
xref: uniprot P42748 241
organism: Arabidopsis thaliana

uniprot Q969T4 505
type: UnificationXref
id: Q969T4
db: uniprot

uniprot P52493 419
type: UnificationXref
id: P52493
db: uniprot

uniprot W4YGS7 173
type: UnificationXref
id: W4YGS7
db: uniprot

Ubiquitin-conjugating enzyme E2 14
type: ProteinReference
xref: uniprot P42747 409
organism: Arabidopsis thaliana

Ubiquitin protein ligase
type: ProteinReference
xref: uniprot B7PKN3 306
organism: Ixodes scapularis

uniprot P52487 417
type: UnificationXref
id: P52487
db: uniprot

ncbitaxon 9606 68
type: UnificationXref
id: 9606
db: ncbitaxon

Ubiquitin-conjugating enzyme E2 variant 2
type: ProteinReference
xref: uniprot Q6PEH5 476
organism: Danio rerio

uniprot Q8L7T3 494
type: UnificationXref
id: Q8L7T3
db: uniprot

uniprot Q6ZWY6 477
type: UnificationXref
id: Q6ZWY6
db: uniprot

uniprot G7N2F6 365
type: UnificationXref
id: G7N2F6
db: uniprot

uniprot A2A5Z6 184
type: UnificationXref
id: A2A5Z6
db: uniprot

uniprot H9FXF7 65
type: UnificationXref
id: H9FXF7
db: uniprot

uniprot F7BSZ9 546
type: UnificationXref
id: F7BSZ9
db: uniprot

uniprot P63146 433
type: UnificationXref
id: P63146
db: uniprot

Danio rerio
type: BioSource
xref: ncbitaxon 7955 12

uniprot G2HJS6 550
type: UnificationXref
id: G2HJS6
db: uniprot

Ubiquitin-conjugating enzyme E2L 3a
type: ProteinReference
xref: uniprot A0A2R8QI56 283
xref: PTHR24068:SF116
organism: Danio rerio

uniprot Q9GNC1 514
type: UnificationXref
id: Q9GNC1
db: uniprot

uniprot P61087 247
type: UnificationXref
id: P61087
db: uniprot

uniprot Q8TI88 139
type: UnificationXref
id: Q8TI88
db: uniprot

Proteasome regulatory ATPase subunit 3
type: ProteinReference
xref: uniprot D6XHJ3 591
organism: Trypanosoma brucei

Ubiquitin-conjugating enzyme E2 D1
type: ProteinReference
xref: uniprot P51668 412
organism: Homo sapiens

Ubiquitin-like modifier-activating enzyme 1
type: ProteinReference
xref: uniprot A3KMV5 185
organism: Bos taurus

26S proteasome non-ATPase regulatory subunit 7
type: ProteinReference
xref: PTHR10540:SF12
xref: uniprot P51665 99
organism: Homo sapiens

E3 ubiquitin-protein ligase
type: ProteinReference
xref: PTHR11254:SF293
xref: uniprot F1MLS5 199
organism: Bos taurus

uniprot Q0UNW6 442
type: UnificationXref
id: Q0UNW6
db: uniprot

uniprot P70711 438
type: UnificationXref
id: P70711
db: uniprot

uniprot B0S6A7 304
type: UnificationXref
id: B0S6A7
db: uniprot

ACTIVE 614
type: EntityFeature
comment: Active state

Uncharacterized protein
type: ProteinReference
xref: uniprot F6SAT6 334
organism: Monodelphis domestica

SH E1 s6 sa4 rs1
type: ModificationFeature
feature location type: SEQUENCE REGION VOCABULARY SH
feature location: SH E1 s6 sa4 rs1 SH
comment: MODIFICATION_RESIDUE_SIDE=outside
comment: MODIFICATION_RESIDUE_TYPE=residue
comment: MODIFICATION_RESIDUE_NAME=SH
comment: MODIFICATION_RESIDUE_ANGLE=0.715273327379819

uniprot O88321 86
type: UnificationXref
id: O88321
db: uniprot

uniprot F7G1C1 357
type: UnificationXref
id: F7G1C1
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot Q0UNW6 442
organism: Phaeosphaeria nodorum

Proteasome-activating nucleotidase
type: ProteinReference
xref: uniprot Q8TI88 139
organism: Methanosarcina acetivorans

Eukaryotic translation initiation factor 3 subunit F
type: ProteinReference
xref: uniprot O43060 79
organism: Schizosaccharomyces pombe

E3 ubiquitin-protein ligase SMURF2
type: ProteinReference
xref: PTHR11254:SF300
xref: uniprot A2A5Z6 184
organism: Mus musculus

Os06g0173100 protein
type: ProteinReference
xref: uniprot Q5SNC0 124
organism: Oryza sativa

Proteasome 26S subunit, non-ATPase 7
type: ProteinReference
xref: uniprot Q5M8I9 123
organism: Xenopus tropicalis

uniprot Q9NED4 516
type: UnificationXref
id: Q9NED4
db: uniprot

uniprot O00102 383
type: UnificationXref
id: O00102
db: uniprot

SUMO-activating enzyme subunit 2
type: ProteinReference
xref: uniprot Q9UBT2 583
organism: Homo sapiens

Ubiquitin-conjugating enzyme-like protein
type: ProteinReference
xref: uniprot Q4QFZ6 460
organism: Leishmania major

PARTICIPANT STOICHIOMETRY r7 628
type: Stoichiometry
physical entity: Pi
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r7 627
type: Stoichiometry
physical entity: a24_degraded
stoichiometric coefficient: 1.0

Ubiquitin-conjugating enzyme E2D 1a
type: ProteinReference
xref: uniprot Q7SXH5 485
organism: Danio rerio

uniprot A9S453 24
type: UnificationXref
id: A9S453
db: uniprot

PARTICIPANT STOICHIOMETRY r7 626
type: Stoichiometry
physical entity: ubiquitin
stoichiometric coefficient: 1.0

uniprot Q15819 444
type: UnificationXref
id: Q15819
db: uniprot

Proteasome 26S subunit, non-ATPase 13
type: ProteinReference
xref: PTHR10539:SF0
xref: uniprot E2R5N5 40
organism: Canis lupus familiaris

PARTICIPANT STOICHIOMETRY r7 625
type: Stoichiometry
physical entity: ADP
stoichiometric coefficient: 1.0

26S proteasome non-ATPase regulatory subunit 4
type: ProteinReference
xref: PTHR10223:SF7
xref: uniprot P55036 100
organism: Homo sapiens

PARTICIPANT STOICHIOMETRY r7 624
type: Stoichiometry
physical entity: Protein target
stoichiometric coefficient: 1.0

Uncharacterized protein
type: ProteinReference
xref: uniprot Q5B9M0 464
organism: Emericella nidulans

UBE2NL isoform 1
type: ProteinReference
xref: uniprot H2R4I1 374
organism: Pan troglodytes

PARTICIPANT STOICHIOMETRY r7 623
type: Stoichiometry
physical entity: ATP
stoichiometric coefficient: 1.0

Ubiquitin-conjugating enzyme E2
type: ProteinReference
xref: uniprot A7F0Q4 289
organism: Sclerotinia sclerotiorum

Three prime repair exonuclease 2
type: ProteinReference
xref: uniprot A0A2I3RTF4 3
organism: Pan troglodytes

Ubiquitin-like modifier-activating enzyme 1
type: ProteinReference
xref: uniprot Q5U300 255
organism: Rattus norvegicus

Ubiquitin-conjugating enzyme E2-18 kDa
type: ProteinReference
xref: uniprot O00102 383
organism: Schizosaccharomyces pombe

uniprot H2QVP1 224
type: UnificationXref
id: H2QVP1
db: uniprot

uniprot O08759 234
type: UnificationXref
id: O08759
db: uniprot

uniprot C3ZMI7 310
type: UnificationXref
id: C3ZMI7
db: uniprot

uniprot Q8VZX3 500
type: UnificationXref
id: Q8VZX3
db: uniprot

uniprot P60605 421
type: UnificationXref
id: P60605
db: uniprot

Ubiquitin-conjugating enzyme E2-20 kDa
type: ProteinReference
xref: uniprot O00103 384
organism: Schizosaccharomyces pombe

UBE2S isoform 1
type: ProteinReference
xref: uniprot K7BPT6 381
organism: Pan troglodytes

uniprot Q9SJ44 521
type: UnificationXref
id: Q9SJ44
db: uniprot

uniprot Q9SJT1 581
type: UnificationXref
id: Q9SJT1
db: uniprot

uniprot F6YMX6 544
type: UnificationXref
id: F6YMX6
db: uniprot

uniprot E1BT61 535
type: UnificationXref
id: E1BT61
db: uniprot

uniprot Q0P5K3 441
type: UnificationXref
id: Q0P5K3
db: uniprot

uniprot P42748 241
type: UnificationXref
id: P42748
db: uniprot

Ubiquitin-conjugating enzyme E2 D1 isoform 1
type: ProteinReference
xref: uniprot G7N2F6 365
organism: Macaca mulatta

Uncharacterized protein
type: ProteinReference
xref: uniprot F7A2Q4 215
organism: Monodelphis domestica

uniprot E2R5N5 40
type: UnificationXref
id: E2R5N5
db: uniprot

uniprot Q7QFT1 483
type: UnificationXref
id: Q7QFT1
db: uniprot

PTHR11254:SF300
type: RelationshipXref
id: PTHR11254:SF300
db: PANTHER Family
relationship type: By Homology

uniprot Q1K7Z3 111
type: UnificationXref
id: Q1K7Z3
db: uniprot

Ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)
type: ProteinReference
xref: uniprot Q6PC58 475
organism: Danio rerio

26S proteasome non-ATPase regulatory subunit 1
type: ProteinReference
xref: uniprot A7MBA2 17
organism: Bos taurus

Ubiquitin-conjugating enzyme E2 E1
type: ProteinReference
xref: uniprot F7C462 349
organism: Xenopus tropicalis

AMP
type: SmallMolecule
cellular location: cytosol
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot A8IV67 20
type: UnificationXref
id: A8IV67
db: uniprot

uniprot O13834 235
type: UnificationXref
id: O13834
db: uniprot

uniprot H2Q6L8 369
type: UnificationXref
id: H2Q6L8
db: uniprot

uniprot P42745 408
type: UnificationXref
id: P42745
db: uniprot

uniprot H2QZ18 373
type: UnificationXref
id: H2QZ18
db: uniprot

E3 ubiquitin-protein ligase
type: ProteinReference
xref: PTHR11254:SF300
xref: uniprot F7EF57 218
organism: Ornithorhynchus anatinus

uniprot A0A2I3RE00 180
type: UnificationXref
id: A0A2I3RE00
db: uniprot

Ubiquitin-conjugating enzyme E2D 3
type: ProteinReference
xref: uniprot A9JRT4 296
organism: Danio rerio

uniprot Q94BQ2 147
type: UnificationXref
id: Q94BQ2
db: uniprot

Proteasome 26S subunit, non-ATPase 7
type: ProteinReference
xref: uniprot J9P6R1 66
organism: Canis lupus familiaris

UBiquitin Conjugating enzyme
type: ProteinReference
xref: uniprot Q9TZ69 524
organism: Caenorhabditis elegans

uniprot P42747 409
type: UnificationXref
id: P42747
db: uniprot

uniprot A0A1D5Q8Y9 178
type: UnificationXref
id: A0A1D5Q8Y9
db: uniprot

26S proteasome regulatory particle non-ATPase subunit11
type: ProteinReference
xref: uniprot Q9SDD1 159
organism: Oryza sativa

uniprot Q94E72 148
type: UnificationXref
id: Q94E72
db: uniprot

E3 ubiquitin-protein ligase
type: ProteinReference
xref: PTHR11254:SF293
xref: uniprot F1QEG9 208
organism: Danio rerio

Rattus norvegicus
type: BioSource
xref: ncbitaxon 10116 33

Predicted protein
type: ProteinReference
xref: uniprot A7RXR8 290
organism: Nematostella vectensis

Ubiquitin-conjugating enzyme E2N-like
type: ProteinReference
xref: uniprot Q7T3F3 486
organism: Danio rerio

uniprot F7C495 350
type: UnificationXref
id: F7C495
db: uniprot

PTHR10410:SF5
type: RelationshipXref
id: PTHR10410:SF5
db: PANTHER Family
relationship type: By Homology

uniprot E9H6I3 45
type: UnificationXref
id: E9H6I3
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A1D5QWJ2 275
organism: Macaca mulatta

Ubiquitin-conjugating enzyme E2 1
type: ProteinReference
xref: uniprot P21734 397
organism: Saccharomyces cerevisiae

Ubiquitin-conjugating enzyme E2 N
type: ProteinReference
xref: uniprot Q0P5K3 441
organism: Bos taurus

Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14
type: ProteinReference
xref: PTHR10410:SF5
xref: uniprot Q17QP9 108
organism: Bos taurus

Daphnia pulex
type: BioSource
xref: ncbitaxon 6669 44

uniprot Q9UTN8 525
type: UnificationXref
id: Q9UTN8
db: uniprot

AER173Cp
type: ProteinReference
xref: uniprot Q756T0 478
organism: Ashbya gossypii

uniprot Q2T9X7 452
type: UnificationXref
id: Q2T9X7
db: uniprot

uniprot Q17820 567
type: UnificationXref
id: Q17820
db: uniprot

Ubiquitin conjugating enzyme E2 D1
type: ProteinReference
xref: uniprot F7G1C1 357
organism: Ornithorhynchus anatinus

uniprot Q9D906 578
type: UnificationXref
id: Q9D906
db: uniprot

uniprot F1NR71 46
type: UnificationXref
id: F1NR71
db: uniprot

Ubiquitin-conjugating enzyme E2 36
type: ProteinReference
xref: uniprot Q9FZ48 513
organism: Arabidopsis thaliana

uniprot Q17QP9 108
type: UnificationXref
id: Q17QP9
db: uniprot

Regulatory particle triple-A ATPase 4
type: ProteinReference
xref: uniprot Q9W414 169
organism: Drosophila melanogaster

Ubiquitin-conjugating enzyme spm2
type: ProteinReference
xref: uniprot O74983 392
organism: Schizosaccharomyces pombe

Uncharacterized protein
type: ProteinReference
xref: uniprot F4PEG9 328
organism: Batrachochytrium dendrobatidis

uniprot F7AQ16 348
type: UnificationXref
id: F7AQ16
db: uniprot

ncbitaxon 237561 390
type: UnificationXref
id: 237561
db: ncbitaxon

uniprot E9FRE8 323
type: UnificationXref
id: E9FRE8
db: uniprot

E3 ubiquitin-protein ligase SMURF2
type: ProteinReference
xref: PTHR11254:SF300
xref: uniprot A9JRZ0 187
organism: Danio rerio

E3 ubiquitin-protein ligase
type: ProteinReference
xref: uniprot H2QWD9 225
organism: Pan troglodytes

uniprot Q05086 250
type: UnificationXref
id: Q05086
db: uniprot

Os06g0600100 protein
type: ProteinReference
xref: uniprot Q69X47 127
organism: Oryza sativa

E3 ubiquitin-protein ligase
type: ProteinReference
xref: uniprot E2RBA6 193
organism: Canis lupus familiaris

Ubiquitin-conjugating enzyme E2 5A
type: ProteinReference
xref: uniprot Q8S920 498
organism: Oryza sativa

Uncharacterized protein
type: ProteinReference
xref: uniprot W4XFS1 171
organism: Strongylocentrotus purpuratus

Uncharacterized protein
type: ProteinReference
xref: PTHR11254:SF293
xref: uniprot F7HPB0 222
organism: Macaca mulatta

PARTICIPANT STOICHIOMETRY r9 621
type: Stoichiometry
physical entity: Complex (ubiquitin/E1)
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r9 622
type: Stoichiometry
physical entity: PPi
stoichiometric coefficient: 1.0

uniprot Q9C5U3 151
type: UnificationXref
id: Q9C5U3
db: uniprot

uniprot Q9ES34 266
type: UnificationXref
id: Q9ES34
db: uniprot

PARTICIPANT STOICHIOMETRY r9 620
type: Stoichiometry
physical entity: ATP
stoichiometric coefficient: 1.0

uniprot F6VSA5 341
type: UnificationXref
id: F6VSA5
db: uniprot

uniprot F1RCA1 540
type: UnificationXref
id: F1RCA1
db: uniprot

Probable E3 ubiquitin-protein ligase mug30
type: ProteinReference
xref: uniprot O94275 237
organism: Schizosaccharomyces pombe

uniprot Q9P7R4 519
type: UnificationXref
id: Q9P7R4
db: uniprot

Os03g0791800 protein
type: ProteinReference
xref: uniprot Q8SBC1 499
organism: Oryza sativa

Ubiquitin-conjugating enzyme E2 5B
type: ProteinReference
xref: uniprot Q8S919 497
organism: Oryza sativa

uniprot P25153 399
type: UnificationXref
id: P25153
db: uniprot

uniprot P79064 563
type: UnificationXref
id: P79064
db: uniprot

Ubiquitin-conjugating enzyme E2 7
type: ProteinReference
xref: uniprot Q42540 458
organism: Arabidopsis thaliana

Dictyostelium purpureum
type: BioSource
xref: ncbitaxon 5786 594

Ubiquitin-conjugating enzyme E2 13
type: ProteinReference
xref: uniprot Q42541 459
organism: Arabidopsis thaliana

UBE2T isoform 1
type: ProteinReference
xref: uniprot H2Q0X0 366
organism: Pan troglodytes

ncbitaxon 367110 110
type: UnificationXref
id: 367110
db: ncbitaxon

uniprot Q9Z1F9 584
type: UnificationXref
id: Q9Z1F9
db: uniprot

SUMO-activating enzyme subunit 2
type: ProteinReference
xref: uniprot Q9Z1F9 584
organism: Mus musculus

PARTICIPANT STOICHIOMETRY r9 618
type: Stoichiometry
physical entity: E1
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r9 619
type: Stoichiometry
physical entity: ubiquitin
stoichiometric coefficient: 1.0

Putative ubiquitin-activating enzyme e1
type: ProteinReference
xref: uniprot Q9NF77 579
organism: Leishmania major

26S proteasome regulatory subunit rpn2
type: ProteinReference
xref: uniprot O74762 82
organism: Schizosaccharomyces pombe

E3 ubiquitin-protein ligase
type: ProteinReference
xref: uniprot K7BGN1 229
organism: Pan troglodytes

Uncharacterized protein
type: ProteinReference
xref: uniprot F7C495 350
organism: Macaca mulatta

uniprot O94444 89
type: UnificationXref
id: O94444
db: uniprot

E3 ubiquitin-protein ligase
type: ProteinReference
xref: uniprot Q7RV01 257
organism: Neurospora crassa

Ubiquitin-conjugating enzyme E2 variant 2
type: ProteinReference
xref: uniprot Q15819 444
organism: Homo sapiens

eco ECO:0000250 6
type: UnificationXref
id: ECO:0000250
db: eco

ncbitaxon 5786 594
type: UnificationXref
id: 5786
db: ncbitaxon

uniprot Q42541 459
type: UnificationXref
id: Q42541
db: uniprot

uniprot Q9MAT0 157
type: UnificationXref
id: Q9MAT0
db: uniprot

uniprot Q9LIM2 154
type: UnificationXref
id: Q9LIM2
db: uniprot

Ubiquitin-like modifier-activating enzyme 7
type: ProteinReference
xref: uniprot P41226 240
organism: Homo sapiens

ncbitaxon 9598 4
type: UnificationXref
id: 9598
db: ncbitaxon

Ubiquitin protein ligase E3C
type: ProteinReference
xref: uniprot D3ZHB7 188
organism: Rattus norvegicus

Ubiquitin conjugating enzyme E2 T
type: ProteinReference
xref: uniprot E2RGY5 318
organism: Canis lupus familiaris

26S proteasome regulatory subunit rpn10
type: ProteinReference
xref: PTHR10223:SF0
xref: uniprot O94444 89
organism: Schizosaccharomyces pombe

Putative ubiquitin-conjugating enzyme e2
type: ProteinReference
xref: uniprot Q9NED4 516
organism: Leishmania major

Os06g0607800 protein
type: ProteinReference
xref: uniprot Q69Q32 126
organism: Oryza sativa

Emericella nidulans
type: BioSource
xref: ncbitaxon 227321 119

uniprot F1N703 202
type: UnificationXref
id: F1N703
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F6TXY0 339
organism: Monodelphis domestica

Uncharacterized protein
type: ProteinReference
xref: uniprot F7G1G8 358
organism: Monodelphis domestica

ncbitaxon 9615 41
type: UnificationXref
id: 9615
db: ncbitaxon

uniprot C3XXY6 36
type: UnificationXref
id: C3XXY6
db: uniprot

uniprot E2QUU3 191
type: UnificationXref
id: E2QUU3
db: uniprot

Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
type: ProteinReference
xref: uniprot Q7ZUK1 488
organism: Danio rerio

Ubiquitin conjugating enzyme E2 C
type: ProteinReference
xref: uniprot E2RN95 321
organism: Canis lupus familiaris

uniprot A0A2I3S463 5
type: UnificationXref
id: A0A2I3S463
db: uniprot

uniprot P38886 94
type: UnificationXref
id: P38886
db: uniprot

uniprot Q6DGE1 471
type: UnificationXref
id: Q6DGE1
db: uniprot

Ubiquitin-conjugating enzyme E2 G1
type: ProteinReference
xref: uniprot P62254 429
organism: Mus musculus

E3 ubiquitin-protein ligase
type: ProteinReference
xref: PTHR11254:SF293
xref: uniprot H2R545 226
organism: Pan troglodytes

Ubiquitin-conjugating enzyme E2 G1
type: ProteinReference
xref: uniprot P62255 430
organism: Rattus norvegicus

Ubiquitin-conjugating enzyme E2 G1
type: ProteinReference
xref: uniprot P62253 428
organism: Homo sapiens

uniprot F1M3F2 196
type: UnificationXref
id: F1M3F2
db: uniprot

uniprot Q32PG0 253
type: UnificationXref
id: Q32PG0
db: uniprot

UBE2L6 isoform 2
type: ProteinReference
xref: PTHR24068:SF43
xref: uniprot H2Q3P2 368
organism: Pan troglodytes

26S proteasome regulatory subunit 6B
type: ProteinReference
xref: uniprot Q3T030 602
organism: Bos taurus

MDM2 proto-oncogene
type: ProteinReference
xref: PTHR13844:SF15
xref: uniprot A0A2I3RE00 180
organism: Pan troglodytes

uniprot Q6PC58 475
type: UnificationXref
id: Q6PC58
db: uniprot

uniprot P34123 599
type: UnificationXref
id: P34123
db: uniprot

26S proteasome non-ATPase regulatory subunit 2
type: ProteinReference
xref: uniprot P56701 101
organism: Bos taurus

uniprot Q7RVS7 484
type: UnificationXref
id: Q7RVS7
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A2I3SAT6 281
organism: Pan troglodytes

uniprot Q8W0I1 501
type: UnificationXref
id: Q8W0I1
db: uniprot

uniprot E1BQY2 314
type: UnificationXref
id: E1BQY2
db: uniprot

STATE_TRANSITION_LEFT__E2-_Protein_target-RIGHT__E2-_Protein_target-_r12
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r12 631
participant stoichiometry: PARTICIPANT STOICHIOMETRY r12 630
participant stoichiometry: PARTICIPANT STOICHIOMETRY r12 629
participant stoichiometry: PARTICIPANT STOICHIOMETRY r12 632
left: E2
left: Protein target
interaction type: STATE_TRANSITION
right: Protein target
right: E2

uniprot P68037 437
type: UnificationXref
id: P68037
db: uniprot

UBE2N isoform 2
type: ProteinReference
xref: uniprot H2Q6L8 369
organism: Pan troglodytes

Complex (ubiquitin/E1)
type: Complex
component stoichiometry: ubiquitin s5 sa3 STOICHIOMETRY ID COMPLEX
component stoichiometry: E1 s6 sa4 STOICHIOMETRY ID COMPLEX
component: E1
component: ubiquitin
feature: COMPLEX BINDING FEATURE s9 a11 610
feature: ACTIVE 614
feature: COMPLEX BINDING FEATURE s9 a11 612
cellular location: cytosol

uniprot Q99460 149
type: UnificationXref
id: Q99460
db: uniprot

WW domain-containing E3 ubiquitin protein ligase 2 (Fragment)
type: ProteinReference
xref: uniprot F7EYF1 219
organism: Rattus norvegicus

Putative ubiquitin-conjugating enzyme E2 N-like
type: ProteinReference
xref: uniprot Q5JXB2 465
organism: Homo sapiens

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__ATP-_Protein_target-RIGHT__ADP-_ubiquitin-_a24_degraded-_Pi-_r7
controller: Complex (26S proteasome/19S proteasome)

uniprot A0A1D5QQB8 274
type: UnificationXref
id: A0A1D5QQB8
db: uniprot

DNA damage tolerance protein rad31
type: ProteinReference
xref: uniprot P79064 563
organism: Schizosaccharomyces pombe

26S proteasome regulatory subunit rpn12
type: ProteinReference
xref: uniprot P50524 98
organism: Schizosaccharomyces pombe

Ubiquitin-conjugating enzyme E2 B
type: ProteinReference
xref: uniprot Q6DDC8 470
organism: Xenopus tropicalis

Huntingtin interacting protein 2 (Predicted), isoform CRA_a
type: ProteinReference
xref: uniprot D3ZXS8 189
organism: Rattus norvegicus

Ubiquitin-conjugating enzyme E2 G1
type: ProteinReference
xref: uniprot F6Y655 344
organism: Xenopus tropicalis

uniprot H2QL51 371
type: UnificationXref
id: H2QL51
db: uniprot

Ubiquitin-conjugating enzyme E2
type: ProteinReference
xref: uniprot Q7RVS7 484
organism: Neurospora crassa

ADP
type: SmallMolecule
cellular location: cytosol
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot A9SLJ8 301
type: UnificationXref
id: A9SLJ8
db: uniprot

uniprot Q9NF77 579
type: UnificationXref
id: Q9NF77
db: uniprot

uniprot F1MGQ5 198
type: UnificationXref
id: F1MGQ5
db: uniprot

uniprot P46465 96
type: UnificationXref
id: P46465
db: uniprot

uniprot Q8BZZ3 260
type: UnificationXref
id: Q8BZZ3
db: uniprot

uniprot F7EGU4 59
type: UnificationXref
id: F7EGU4
db: uniprot

SUMO-activating enzyme subunit aos-1
type: ProteinReference
xref: uniprot Q17820 567
organism: Caenorhabditis elegans

uniprot F6U235 212
type: UnificationXref
id: F6U235
db: uniprot

uniprot A0A3Q1LV60 284
type: UnificationXref
id: A0A3Q1LV60
db: uniprot

Predicted protein
type: ProteinReference
xref: uniprot A9TIG8 302
organism: Physcomitrella patens

E1
type: Protein
entity reference: E1
feature: SH E1 s6 sa4 rs1
feature: COMPLEX PARTICIPANT BINDING FEATURE s6 sa4 613
cellular location: cytosol
comment: SPECIES_TYPE=PROTEIN

Saccharomyces cerevisiae
type: BioSource
xref: ncbitaxon 559292 92

Ubiquitin-conjugating enzyme E2 D1
type: ProteinReference
xref: uniprot P61080 425
organism: Mus musculus

Drosophila melanogaster
type: BioSource
xref: ncbitaxon 7227 133

uniprot P35134 406
type: UnificationXref
id: P35134
db: uniprot

uniprot O74810 391
type: UnificationXref
id: O74810
db: uniprot

Ubiquitin-conjugating enzyme E2 K
type: ProteinReference
xref: uniprot P61085 245
organism: Bos taurus

E3 ubiquitin-protein ligase SMURF1
type: ProteinReference
xref: PTHR11254:SF293
xref: uniprot Q9HCE7 269
organism: Homo sapiens

uniprot A9S5I6 25
type: UnificationXref
id: A9S5I6
db: uniprot

Ubiquitin-conjugating enzyme E2G 1a (UBC7 homolog, yeast)
type: ProteinReference
xref: uniprot Q7ZVK2 489
organism: Danio rerio

Ubiquitin-conjugating enzyme E2 N
type: ProteinReference
xref: uniprot P61089 427
organism: Mus musculus

Ubiquitin-conjugating enzyme E2 N
type: ProteinReference
xref: uniprot P61088 426
organism: Homo sapiens

Ubiquitin-conjugating enzyme E2 K
type: ProteinReference
xref: uniprot P61087 247
organism: Mus musculus

PTHR10758:SF2
type: RelationshipXref
id: PTHR10758:SF2
db: PANTHER Family
relationship type: By Homology

Ubiquitin-conjugating enzyme E2 K
type: ProteinReference
xref: uniprot P61086 246
organism: Homo sapiens

uniprot Q9QZU9 520
type: UnificationXref
id: Q9QZU9
db: uniprot

uniprot Q62940 256
type: UnificationXref
id: Q62940
db: uniprot

uniprot Q9HCE7 269
type: UnificationXref
id: Q9HCE7
db: uniprot

Ubiquitin-conjugating enzyme E2 D3
type: ProteinReference
xref: uniprot P61079 424
organism: Mus musculus

uniprot Q9W414 169
type: UnificationXref
id: Q9W414
db: uniprot

uniprot P49459 411
type: UnificationXref
id: P49459
db: uniprot

uniprot G2HJQ1 61
type: UnificationXref
id: G2HJQ1
db: uniprot

uniprot J9NTA2 379
type: UnificationXref
id: J9NTA2
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot W4YGS7 173
organism: Strongylocentrotus purpuratus

uniprot O42939 555
type: UnificationXref
id: O42939
db: uniprot

E3 ubiquitin-protein ligase
type: ProteinReference
xref: PTHR11254:SF293
xref: uniprot F7GHZ3 220
organism: Monodelphis domestica

uniprot Q8S1Y5 496
type: UnificationXref
id: Q8S1Y5
db: uniprot

Os01g0673600 protein
type: ProteinReference
xref: uniprot Q8W0I1 501
organism: Oryza sativa

E3 ubiquitin-protein ligase
type: ProteinReference
xref: uniprot H9ERF6 227
organism: Macaca mulatta

E1
type: Protein
entity reference: E1
feature: SH E1 s12 a17 rs1
cellular location: cytosol
comment: SPECIES_TYPE=PROTEIN

Uncharacterized protein
type: ProteinReference
xref: uniprot F6Z480 346
organism: Monodelphis domestica

uniprot O48838 388
type: UnificationXref
id: O48838
db: uniprot

Ubiquitin-conjugating enzyme E2 D1
type: ProteinReference
xref: uniprot A0JM78 286
organism: Xenopus tropicalis

uniprot F7GHZ3 220
type: UnificationXref
id: F7GHZ3
db: uniprot

Plasmodium falciparum
type: BioSource
xref: ncbitaxon 36329 84

uniprot Q28G19 450
type: UnificationXref
id: Q28G19
db: uniprot

uniprot A9U4R7 303
type: UnificationXref
id: A9U4R7
db: uniprot

ncbitaxon 13616 57
type: UnificationXref
id: 13616
db: ncbitaxon

a24_degraded
type: PhysicalEntity
cellular location: cytosol
comment: SPECIES_TYPE=DEGRADED

Uncharacterized protein
type: ProteinReference
xref: PTHR10410:SF5
xref: uniprot W4YTT9 174
organism: Strongylocentrotus purpuratus

uniprot Q9D2M8 509
type: UnificationXref
id: Q9D2M8
db: uniprot

uniprot Q9SZD4 166
type: UnificationXref
id: Q9SZD4
db: uniprot

26S proteasome non-ATPase regulatory subunit 1
type: ProteinReference
xref: uniprot H9FXF7 65
organism: Macaca mulatta

uniprot H2QM68 372
type: UnificationXref
id: H2QM68
db: uniprot

PTHR10540:SF7
type: RelationshipXref
id: PTHR10540:SF7
db: PANTHER Family
relationship type: By Homology

E3 ubiquitin-protein ligase Itchy homolog
type: ProteinReference
xref: uniprot Q96J02 263
organism: Homo sapiens

uniprot H2Q0X0 366
type: UnificationXref
id: H2Q0X0
db: uniprot

Ubiquitin-conjugating enzyme E2 S
type: ProteinReference
xref: uniprot Q16763 445
organism: Homo sapiens

uniprot Q00987 248
type: UnificationXref
id: Q00987
db: uniprot

E3 ubiquitin-protein ligase
type: ProteinReference
xref: PTHR11254:SF300
xref: uniprot A0A2I3TGY5 182
organism: Pan troglodytes

uniprot C8VJ79 590
type: UnificationXref
id: C8VJ79
db: uniprot

uniprot P93028 565
type: UnificationXref
id: P93028
db: uniprot

Ubiquitin-conjugating enzyme E2 D4
type: ProteinReference
xref: uniprot F6PPG7 330
organism: Macaca mulatta

26S proteasome regulatory subunit rpn1
type: ProteinReference
xref: uniprot P87048 102
organism: Schizosaccharomyces pombe

uniprot Q9R1T2 580
type: UnificationXref
id: Q9R1T2
db: uniprot

uniprot F7CHT9 56
type: UnificationXref
id: F7CHT9
db: uniprot

PPi
type: SmallMolecule
cellular location: cytosol
comment: SPECIES_TYPE=SIMPLE_MOLECULE

26S proteasome non-ATPase regulatory subunit 1 homolog B
type: ProteinReference
xref: uniprot Q9MAT0 157
organism: Arabidopsis thaliana

Xenopus tropicalis
type: BioSource
xref: ncbitaxon 8364 53

uniprot A9JRZ0 187
type: UnificationXref
id: A9JRZ0
db: uniprot

Ubiquitin-conjugating enzyme E2 S
type: ProteinReference
xref: uniprot Q1RML1 447
organism: Bos taurus

Ubiquitin-conjugating enzyme E2 B
type: ProteinReference
xref: uniprot P63147 434
organism: Mus musculus

Ubiquitin-conjugating enzyme E2 B
type: ProteinReference
xref: uniprot P63149 435
organism: Rattus norvegicus

uniprot F7HMU1 221
type: UnificationXref
id: F7HMU1
db: uniprot

Probable E3 ubiquitin-protein ligase HUL5
type: ProteinReference
xref: uniprot P53119 244
organism: Saccharomyces cerevisiae

Ubiquitin-conjugating enzyme E2 B
type: ProteinReference
xref: uniprot P63146 433
organism: Homo sapiens

Ubiquitin-conjugating enzyme E2 D3
type: ProteinReference
xref: uniprot P61077 422
organism: Homo sapiens

uniprot Q13200 107
type: UnificationXref
id: Q13200
db: uniprot

Ubiquitin-conjugating enzyme E2 D3
type: ProteinReference
xref: uniprot P61078 423
organism: Rattus norvegicus

uniprot P53119 244
type: UnificationXref
id: P53119
db: uniprot

Ubiquitin conjugating enzyme E2 L5
type: ProteinReference
xref: uniprot F7EVY1 354
xref: PTHR24068:SF170
organism: Macaca mulatta

Ubiquitin conjugating enzyme E2 E3
type: ProteinReference
xref: uniprot E2RHN3 319
organism: Canis lupus familiaris

Uncharacterized protein
type: ProteinReference
xref: uniprot E1BQY2 314
organism: Gallus gallus

Ubiquitin conjugating enzyme E2 E1
type: ProteinReference
xref: uniprot H2QM68 372
organism: Pan troglodytes

uniprot Q4QFZ6 460
type: UnificationXref
id: Q4QFZ6
db: uniprot

uniprot P61080 425
type: UnificationXref
id: P61080
db: uniprot

uniprot P35133 405
type: UnificationXref
id: P35133
db: uniprot

E1
type: ProteinReference
xref: P01492
standard name: Ubiquitin activating enzyme E1
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_ID_DESC=Ubiquitin proteasome pathway.PROTEIN.GENERIC.E1
comment: ENTITY_REFERENCE_NOTES= Long Name: Ubiquitin activating enzyme E1 Synonym: Synonym not specified Accession: P01492
member entity reference: Ubiquitin-like modifier-activating enzyme ATG7
member entity reference: NEDD8-activating enzyme E1 catalytic subunit
member entity reference: Uncharacterized protein
member entity reference: Ubiquitin-activating enzyme E1 3
member entity reference: SUMO-activating enzyme subunit 2
member entity reference: Ubiquitin-like modifier-activating enzyme 7
member entity reference: Ubiquitin-activating enzyme E1 1
member entity reference: UBA (Human ubiquitin) related
member entity reference: NEDD8-activating enzyme E1 catalytic subunit isoform 1
member entity reference: Ubiquitin-like modifier-activating enzyme 1 Y
member entity reference: DNA damage tolerance protein rad31
member entity reference: SUMO-activating enzyme subunit 1
member entity reference: Putative ubiquitin-activating enzyme e1
member entity reference: UBA7 isoform 1
member entity reference: Ubiquitin-like modifier-activating enzyme 1
member entity reference: Ubiquitin like modifier activating enzyme 3
member entity reference: SAE1 isoform 9
member entity reference: Ubiquitin like modifier activating enzyme 6
member entity reference: Ubiquitin-like modifier-activating enzyme 6
member entity reference: Activator of SUMO 1
member entity reference: Ubiquitin-activating enzyme E1-like
member entity reference: SUMO-activating enzyme subunit 1B-2
member entity reference: Ubiquitin-like modifier-activating enzyme 3
member entity reference: Ubiquitin-activating enzyme E1 2
member entity reference: Ubiquitin like modifier activating enzyme 1
member entity reference: Autophagy related 7
member entity reference: UBA6 isoform 1
member entity reference: SUMO-activating enzyme subunit aos-1
member entity reference: Ubiquitin-like modifier-activating enzyme atg7
member entity reference: NEDD8-activating enzyme E1 regulatory subunit AXL
member entity reference: SUMO-activating enzyme subunit 1A
member entity reference: UBA3 isoform 2

Proteasome 26S subunit, non-ATPase 14
type: ProteinReference
xref: uniprot F1QHE5 49
organism: Danio rerio

Ubiquitin-conjugating enzyme E2 D1
type: ProteinReference
xref: uniprot D3ZDK2 311
organism: Rattus norvegicus

uniprot F6TV67 338
type: UnificationXref
id: F6TV67
db: uniprot

26S proteasome regulatory subunit 6B
type: ProteinReference
xref: uniprot P54775 601
organism: Mus musculus

uniprot F6SAT6 334
type: UnificationXref
id: F6SAT6
db: uniprot

uniprot P15732 396
type: UnificationXref
id: P15732
db: uniprot

26S proteasome regulatory subunit 10B homolog A
type: ProteinReference
xref: uniprot Q9SEI3 161
organism: Arabidopsis thaliana

STATE_TRANSITION_LEFT__E1-_ubiquitin-_ATP-RIGHT__Complex__ubiquitin_E1_-_PPi-_r9
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r9 620
participant stoichiometry: PARTICIPANT STOICHIOMETRY r9 619
participant stoichiometry: PARTICIPANT STOICHIOMETRY r9 621
participant stoichiometry: PARTICIPANT STOICHIOMETRY r9 618
participant stoichiometry: PARTICIPANT STOICHIOMETRY r9 622
left: ATP
left: E1
left: ubiquitin
interaction type: STATE_TRANSITION
right: PPi
right: Complex (ubiquitin/E1)

26S proteasome regulatory subunit 6A homolog A
type: ProteinReference
xref: uniprot Q9SEI2 160
organism: Arabidopsis thaliana

uniprot P92974 564
type: UnificationXref
id: P92974
db: uniprot

uniprot A4FV12 534
type: UnificationXref
id: A4FV12
db: uniprot

26S proteasome regulatory subunit 6B homolog
type: ProteinReference
xref: uniprot Q9SEI4 162
organism: Arabidopsis thaliana

uniprot Q6XJG8 129
type: UnificationXref
id: Q6XJG8
db: uniprot

uniprot F6SSD2 335
type: UnificationXref
id: F6SSD2
db: uniprot

uniprot Q32P99 454
type: UnificationXref
id: Q32P99
db: uniprot

uniprot P61086 246
type: UnificationXref
id: P61086
db: uniprot

uniprot F1PI66 539
type: UnificationXref
id: F1PI66
db: uniprot

Proteasome 26S subunit, non-ATPase 4
type: ProteinReference
xref: uniprot A0A2I3TPZ7 8
xref: PTHR10223:SF7
organism: Pan troglodytes

26S proteasome regulatory particle triple-A ATPase subunit4
type: ProteinReference
xref: uniprot Q9FXT8 153
organism: Oryza sativa

uniprot F7EF57 218
type: UnificationXref
id: F7EF57
db: uniprot

uniprot P54775 601
type: UnificationXref
id: P54775
db: uniprot

uniprot Q10Q05 106
type: UnificationXref
id: Q10Q05
db: uniprot

Ubiquitin protein ligase E3A
type: ProteinReference
xref: uniprot F1PBV3 206
organism: Canis lupus familiaris

26S proteasome non-ATPase regulatory subunit 2
type: ProteinReference
xref: uniprot F6R1X3 50
organism: Macaca mulatta

uniprot Q5M8I9 123
type: UnificationXref
id: Q5M8I9
db: uniprot

26S proteasome regulatory subunit RPN12,putative
type: ProteinReference
xref: uniprot O77345 83
organism: Plasmodium falciparum

uniprot Q96J02 263
type: UnificationXref
id: Q96J02
db: uniprot

uniprot Q7ZUK1 488
type: UnificationXref
id: Q7ZUK1
db: uniprot

ncbitaxon 7227 133
type: UnificationXref
id: 7227
db: ncbitaxon

Uncharacterized protein
type: ProteinReference
xref: PTHR10410:SF5
xref: uniprot C3XXY6 36
organism: Branchiostoma floridae

STATE_TRANSITION_LEFT__ATP-_Protein_target-RIGHT__ADP-_ubiquitin-_a24_degraded-_Pi-_r7
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r7 625
participant stoichiometry: PARTICIPANT STOICHIOMETRY r7 626
participant stoichiometry: PARTICIPANT STOICHIOMETRY r7 624
participant stoichiometry: PARTICIPANT STOICHIOMETRY r7 627
participant stoichiometry: PARTICIPANT STOICHIOMETRY r7 628
participant stoichiometry: PARTICIPANT STOICHIOMETRY r7 623
left: Protein target
left: ATP
interaction type: STATE_TRANSITION
right: Pi
right: a24_degraded
right: ADP
right: ubiquitin

uniprot Q9UBT2 583
type: UnificationXref
id: Q9UBT2
db: uniprot

uniprot Q9SDD1 159
type: UnificationXref
id: Q9SDD1
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A3Q1LXA9 530
organism: Bos taurus

uniprot V5IMY0 586
type: UnificationXref
id: V5IMY0
db: uniprot

ncbitaxon 7165 135
type: UnificationXref
id: 7165
db: ncbitaxon

uniprot P62838 432
type: UnificationXref
id: P62838
db: uniprot

uniprot Q9H0M0 267
type: UnificationXref
id: Q9H0M0
db: uniprot

Ubiquitin-conjugating enzyme E2 D1
type: ProteinReference
xref: uniprot Q2TA10 453
organism: Bos taurus

OTTXETP00000006803
type: ProteinReference
xref: uniprot Q66JJ6 604
organism: Xenopus tropicalis

Predicted protein
type: ProteinReference
xref: uniprot A7S6Q0 291
organism: Nematostella vectensis

uniprot P23566 398
type: UnificationXref
id: P23566
db: uniprot

Ubiquitin-conjugating enzyme E2
type: ProteinReference
xref: uniprot A7EC83 288
organism: Sclerotinia sclerotiorum

uniprot Q9SEI3 161
type: UnificationXref
id: Q9SEI3
db: uniprot

26S proteasome non-ATPase regulatory subunit 2 homolog B
type: ProteinReference
xref: uniprot Q6XJG8 129
organism: Arabidopsis thaliana

uniprot Q9ZV69 585
type: UnificationXref
id: Q9ZV69
db: uniprot

Protein target
type: Protein
feature: Lysine Protein target s4 a4 rs1
cellular location: cytosol
comment: SPECIES_TYPE=PROTEIN

Os01g0819400 protein
type: ProteinReference
xref: uniprot A0A0P0V9Q4 271
organism: Oryza sativa

uniprot P61089 427
type: UnificationXref
id: P61089
db: uniprot

uniprot Q5ZLH8 467
type: UnificationXref
id: Q5ZLH8
db: uniprot

Ubiquitin-protein ligase E3C
type: ProteinReference
xref: uniprot Q80U95 259
organism: Mus musculus

uniprot F7BMV0 545
type: UnificationXref
id: F7BMV0
db: uniprot

uniprot Q9FZ48 513
type: UnificationXref
id: Q9FZ48
db: uniprot

26S proteasome non-ATPase regulatory subunit 2 homolog A
type: ProteinReference
xref: uniprot Q9SIV2 163
organism: Arabidopsis thaliana

Ubiquitin-like modifier-activating enzyme ATG7
type: ProteinReference
xref: uniprot Q641Y5 570
organism: Rattus norvegicus

uniprot A0A2R8Q5H4 11
type: UnificationXref
id: A0A2R8Q5H4
db: uniprot

uniprot A4QNX5 287
type: UnificationXref
id: A4QNX5
db: uniprot

Ubiquitin like modifier activating enzyme 3
type: ProteinReference
xref: uniprot F6Y460 543
organism: Canis lupus familiaris

Ubiquitin-conjugating enzyme E2 7
type: ProteinReference
xref: uniprot Q02159 439
organism: Saccharomyces cerevisiae

uniprot Q9P7S2 158
type: UnificationXref
id: Q9P7S2
db: uniprot

uniprot Q789K9 480
type: UnificationXref
id: Q789K9
db: uniprot

uniprot A0A2R8QI56 283
type: UnificationXref
id: A0A2R8QI56
db: uniprot

uniprot F7CL20 352
type: UnificationXref
id: F7CL20
db: uniprot

26S proteasome non-ATPase regulatory subunit 4 homolog
type: ProteinReference
xref: uniprot O82143 85
organism: Oryza sativa

26S proteasome non-ATPase regulatory subunit 2
type: ProteinReference
xref: uniprot E2RCP9 42
organism: Canis lupus familiaris

Ubiquitin-conjugating enzyme E2 D2
type: ProteinReference
xref: uniprot Q1RMX2 448
organism: Bos taurus

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A1D5QWZ3 276
organism: Macaca mulatta

uniprot Q8SBC1 499
type: UnificationXref
id: Q8SBC1
db: uniprot

uniprot Q3TXS7 112
type: UnificationXref
id: Q3TXS7
db: uniprot

uniprot P60604 420
type: UnificationXref
id: P60604
db: uniprot

Os05g0460200 protein
type: ProteinReference
xref: uniprot Q6L508 474
organism: Oryza sativa

NEDD8-activating enzyme E1 catalytic subunit
type: ProteinReference
xref: uniprot O65041 556
organism: Arabidopsis thaliana

26S proteasome regulatory subunit 8 homolog B
type: ProteinReference
xref: uniprot Q94BQ2 147
organism: Arabidopsis thaliana

26S protease regulatory subunit 7
type: ProteinReference
xref: uniprot Q7SDQ8 136
organism: Neurospora crassa

Ubiquitin conjugating enzyme E2 B
type: ProteinReference
xref: uniprot A0A2I3SGQ4 282
organism: Pan troglodytes

Ubiquitin-conjugating enzyme E2 E3
type: ProteinReference
xref: uniprot Q2T9X7 452
organism: Bos taurus

Proteasome 26S subunit, non-ATPase 4
type: ProteinReference
xref: PTHR10223:SF0
xref: uniprot F1PRW0 47
organism: Canis lupus familiaris

uniprot Q9Y2X8 527
type: UnificationXref
id: Q9Y2X8
db: uniprot

Bos taurus
type: BioSource
xref: ncbitaxon 9913 14

Ubiquitin-protein ligase E3B
type: ProteinReference
xref: uniprot Q7Z3V4 258
organism: Homo sapiens

uniprot D3ZDK2 311
type: UnificationXref
id: D3ZDK2
db: uniprot

ncbitaxon 10116 33
type: UnificationXref
id: 10116
db: ncbitaxon

Ornithorhynchus anatinus
type: BioSource
xref: ncbitaxon 9258 55

26S proteasome regulatory subunit 6B
type: ProteinReference
xref: uniprot P43686 600
organism: Homo sapiens

uniprot F7G1G8 358
type: UnificationXref
id: F7G1G8
db: uniprot

Proteasome 26S subunit, non-ATPase 13
type: ProteinReference
xref: uniprot A0A2I3S463 5
xref: PTHR10539:SF0
organism: Pan troglodytes

uniprot E2RGH5 194
type: UnificationXref
id: E2RGH5
db: uniprot

26S proteasome non-ATPase regulatory subunit 2
type: ProteinReference
xref: uniprot Q13200 107
organism: Homo sapiens

Uncharacterized protein
type: ProteinReference
xref: uniprot E1BT61 535
organism: Gallus gallus

uniprot P35131 404
type: UnificationXref
id: P35131
db: uniprot

E3 ubiquitin-protein ligase
type: ProteinReference
xref: PTHR11254:SF293
xref: uniprot F6TJ28 211
organism: Ornithorhynchus anatinus

Ubiquitin-conjugating enzyme E2 L3
type: ProteinReference
xref: uniprot P68037 437
xref: PTHR24068:SF67
organism: Mus musculus

Ubiquitin-conjugating enzyme E2 L3
type: ProteinReference
xref: uniprot P68036 436
xref: PTHR24068:SF67
organism: Homo sapiens

uniprot F4PEG9 328
type: UnificationXref
id: F4PEG9
db: uniprot

uniprot H2QPJ4 552
type: UnificationXref
id: H2QPJ4
db: uniprot

uniprot E2RKT9 320
type: UnificationXref
id: E2RKT9
db: uniprot

uniprot D3ZYE1 313
type: UnificationXref
id: D3ZYE1
db: uniprot

SUMO-activating enzyme subunit 1
type: ProteinReference
xref: uniprot Q9UBE0 582
organism: Homo sapiens

uniprot Q66JJ6 604
type: UnificationXref
id: Q66JJ6
db: uniprot

Ubiquitin conjugating enzyme E2 D3
type: ProteinReference
xref: uniprot F7FZ60 355
organism: Ornithorhynchus anatinus

Os02g0634800 protein
type: ProteinReference
xref: uniprot Q6H7I5 473
organism: Oryza sativa

uniprot A7S6Q0 291
type: UnificationXref
id: A7S6Q0
db: uniprot

uniprot A0A2I3S6N5 280
type: UnificationXref
id: A0A2I3S6N5
db: uniprot

Ixodes scapularis
type: BioSource
xref: ncbitaxon 6945 307

uniprot Q7T3F3 486
type: UnificationXref
id: Q7T3F3
db: uniprot

uniprot P21734 397
type: UnificationXref
id: P21734
db: uniprot

Predicted protein
type: ProteinReference
xref: uniprot A9TVX5 31
organism: Physcomitrella patens

Ubiquitin-conjugating enzyme E2 N
type: ProteinReference
xref: uniprot Q9EQX9 510
organism: Rattus norvegicus

uniprot Q09765 566
type: UnificationXref
id: Q09765
db: uniprot

uniprot F6W7A5 342
type: UnificationXref
id: F6W7A5
db: uniprot

uniprot F7AZ85 54
type: UnificationXref
id: F7AZ85
db: uniprot

Ubiquitin-conjugating enzyme E2 14
type: ProteinReference
xref: uniprot Q9UTN8 525
organism: Schizosaccharomyces pombe

ncbitaxon 684364 329
type: UnificationXref
id: 684364
db: ncbitaxon

Ubiquitin-activating enzyme E1 3
type: ProteinReference
xref: uniprot V5IMY0 586
organism: Neurospora crassa

uniprot F7CS21 58
type: UnificationXref
id: F7CS21
db: uniprot

Ubiquitin-conjugating enzyme E2, putative
type: ProteinReference
xref: uniprot Q57W45 462
organism: Trypanosoma brucei

uniprot Q943L1 504
type: UnificationXref
id: Q943L1
db: uniprot

Ubiquitin-conjugating enzyme E2D 4 (putative)
type: ProteinReference
xref: uniprot A4QNX5 287
organism: Danio rerio

Canis lupus familiaris
type: BioSource
xref: ncbitaxon 9615 41

uniprot F1NKD9 325
type: UnificationXref
id: F1NKD9
db: uniprot

uniprot F6Y655 344
type: UnificationXref
id: F6Y655
db: uniprot

PARTICIPANT STOICHIOMETRY r11 636
type: Stoichiometry
physical entity: E2
stoichiometric coefficient: 1.0

uniprot P62837 431
type: UnificationXref
id: P62837
db: uniprot

PARTICIPANT STOICHIOMETRY r11 635
type: Stoichiometry
physical entity: E1
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r11 634
type: Stoichiometry
physical entity: E1
stoichiometric coefficient: 1.0

Putative proteasome regulatory non-ATP-ase subunit
type: ProteinReference
xref: uniprot Q4QDA3 115
organism: Leishmania major

uniprot O94275 237
type: UnificationXref
id: O94275
db: uniprot

PARTICIPANT STOICHIOMETRY r11 633
type: Stoichiometry
physical entity: E2
stoichiometric coefficient: 1.0

uniprot P35129 403
type: UnificationXref
id: P35129
db: uniprot

uniprot E9I205 324
type: UnificationXref
id: E9I205
db: uniprot

Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)
type: ProteinReference
xref: uniprot Q4V9I8 461
organism: Danio rerio

uniprot Q99MI7 577
type: UnificationXref
id: Q99MI7
db: uniprot

uniprot Q8S919 497
type: UnificationXref
id: Q8S919
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F1NKD9 325
xref: PTHR48177:SF1
organism: Gallus gallus

26S proteasome regulatory subunit 4 homolog B
type: ProteinReference
xref: uniprot Q9SL67 164
organism: Arabidopsis thaliana

26S proteasome non-ATPase regulatory subunit 11
type: ProteinReference
xref: PTHR10678:SF2
xref: uniprot Q1K564 109
organism: Neurospora crassa

PTHR10540:SF12
type: RelationshipXref
id: PTHR10540:SF12
db: PANTHER Family
relationship type: By Homology

Novel protein (Zgc:63709)
type: ProteinReference
xref: uniprot B0R1D0 589
organism: Danio rerio

26S proteasome non-ATPase regulatory subunit 14 homolog
type: ProteinReference
xref: uniprot Q9LT08 155
xref: PTHR10410:SF27
organism: Arabidopsis thaliana

uniprot Q9D1C1 508
type: UnificationXref
id: Q9D1C1
db: uniprot

Gallus gallus
type: BioSource
xref: ncbitaxon 9031 39

Uncharacterized protein
type: ProteinReference
xref: uniprot F1PYX5 327
organism: Canis lupus familiaris

Ubiquitin-activating enzyme E1-like
type: ProteinReference
xref: uniprot O42939 555
organism: Schizosaccharomyces pombe

Os01g0511300 protein
type: ProteinReference
xref: uniprot Q94E72 148
organism: Oryza sativa

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A3Q1LV60 284
organism: Bos taurus

uniprot F6TQE0 337
type: UnificationXref
id: F6TQE0
db: uniprot

Ubiquitin-conjugating enzyme E2 L3
type: ProteinReference
xref: uniprot Q3MHP1 456
xref: PTHR24068:SF67
organism: Bos taurus

uniprot F1PX57 48
type: UnificationXref
id: F1PX57
db: uniprot

uniprot O43060 79
type: UnificationXref
id: O43060
db: uniprot

Ubiquitin-activating enzyme E1 1
type: ProteinReference
xref: uniprot O94609 557
organism: Schizosaccharomyces pombe

uniprot F7CZ16 353
type: UnificationXref
id: F7CZ16
db: uniprot

uniprot Q9FMM0 512
type: UnificationXref
id: Q9FMM0
db: uniprot

26S proteasome non-ATPase regulatory subunit 12 homolog B
type: ProteinReference
xref: uniprot Q8VWK0 142
organism: Arabidopsis thaliana

uniprot A0A3Q1MJI4 531
type: UnificationXref
id: A0A3Q1MJI4
db: uniprot

26S proteasome
type: Protein
entity reference: 26S proteasome
feature: COMPLEX PARTICIPANT BINDING FEATURE s16 sa1 607
cellular location: cytosol
comment: SPECIES_TYPE=PROTEIN

uniprot Q9SL67 164
type: UnificationXref
id: Q9SL67
db: uniprot

Ubiquitin-conjugating enzyme E2A
type: ProteinReference
xref: uniprot Q6AXR9 469
organism: Rattus norvegicus

uniprot Q7RV01 257
type: UnificationXref
id: Q7RV01
db: uniprot

uniprot E2RH48 592
type: UnificationXref
id: E2RH48
db: uniprot

uniprot Q02053 249
type: UnificationXref
id: Q02053
db: uniprot

Ubiquitin-conjugating enzyme E2 L3
type: ProteinReference
xref: PTHR24068:SF116
xref: uniprot F6W7B6 343
organism: Xenopus tropicalis

uniprot F7ESQ7 548
type: UnificationXref
id: F7ESQ7
db: uniprot

uniprot O14326 236
type: UnificationXref
id: O14326
db: uniprot

NEDD8-activating enzyme E1 catalytic subunit
type: ProteinReference
xref: uniprot Q19360 568
organism: Caenorhabditis elegans

Uncharacterized protein
type: ProteinReference
xref: PTHR10410:SF5
xref: uniprot E1C6N0 38
organism: Gallus gallus

Ubiquitin-conjugating enzyme E2 variant 1C
type: ProteinReference
xref: uniprot Q9SJ44 521
organism: Arabidopsis thaliana

Ubiquitin conjugating enzyme E2 N like (gene/pseudogene)
type: ProteinReference
xref: uniprot F6Q430 331
organism: Ornithorhynchus anatinus

Predicted protein
type: ProteinReference
xref: uniprot A7RQF7 18
organism: Nematostella vectensis

Os09g0297100 protein
type: ProteinReference
xref: uniprot Q69TB0 468
organism: Oryza sativa

uniprot H9ERF6 227
type: UnificationXref
id: H9ERF6
db: uniprot

UBE2K isoform 1
type: ProteinReference
xref: uniprot G2HEI6 223
organism: Pan troglodytes

uniprot Q7ZVK2 489
type: UnificationXref
id: Q7ZVK2
db: uniprot

uniprot P52482 414
type: UnificationXref
id: P52482
db: uniprot

uniprot Q8W422 143
type: UnificationXref
id: Q8W422
db: uniprot

uniprot E2RN95 321
type: UnificationXref
id: E2RN95
db: uniprot

E3 ubiquitin-protein ligase pub2
type: ProteinReference
xref: uniprot Q9UTG2 270
organism: Schizosaccharomyces pombe

uniprot A9T0R6 28
type: UnificationXref
id: A9T0R6
db: uniprot

26S proteasome non-ATPase regulatory subunit 4
type: ProteinReference
xref: PTHR10223:SF0
xref: uniprot O35226 74
organism: Mus musculus

26S proteasome non-ATPase regulatory subunit 2
type: ProteinReference
xref: uniprot H2QNV3 64
organism: Pan troglodytes

uniprot Q15386 251
type: UnificationXref
id: Q15386
db: uniprot

Ubiquitin-conjugating enzyme E2 N
type: ProteinReference
xref: uniprot F6W7A5 342
organism: Xenopus tropicalis

uniprot K7BK39 230
type: UnificationXref
id: K7BK39
db: uniprot

ncbitaxon 7668 172
type: UnificationXref
id: 7668
db: ncbitaxon

Antisecretory factor
type: ProteinReference
xref: PTHR10223:SF0
xref: uniprot O88321 86
organism: Rattus norvegicus

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A1D5Q067 272
organism: Macaca mulatta

26S proteasome non-ATPase regulatory subunit 1
type: ProteinReference
xref: uniprot F6WGT0 52
organism: Xenopus tropicalis

uniprot O00308 233
type: UnificationXref
id: O00308
db: uniprot

SUMO-activating enzyme subunit 1
type: ProteinReference
xref: uniprot Q6AXQ0 571
organism: Rattus norvegicus

Ubiquitin-like modifier-activating enzyme ATG7
type: ProteinReference
xref: uniprot Q9D906 578
organism: Mus musculus

Uncharacterized protein
type: ProteinReference
xref: uniprot H3EGL4 375
organism: Pristionchus pacificus

uniprot D3ZHB7 188
type: UnificationXref
id: D3ZHB7
db: uniprot

AGAP000145-PA
type: ProteinReference
xref: uniprot Q7PRY1 482
organism: Anopheles gambiae

Uncharacterized protein
type: ProteinReference
xref: uniprot F7HMU1 221
organism: Macaca mulatta

uniprot A0A2I3SJZ1 181
type: UnificationXref
id: A0A2I3SJZ1
db: uniprot

uniprot W4XFS1 171
type: UnificationXref
id: W4XFS1
db: uniprot

26S proteasome non-ATPase regulatory subunit 1
type: ProteinReference
xref: uniprot Q3TXS7 112
organism: Mus musculus

E3 ubiquitin-protein ligase ptr1
type: ProteinReference
xref: uniprot O13834 235
organism: Schizosaccharomyces pombe

Predicted protein
type: ProteinReference
xref: uniprot A9T0R6 28
organism: Physcomitrella patens

Ubiquitin-conjugating enzyme E2 E3
type: ProteinReference
xref: uniprot Q969T4 505
organism: Homo sapiens

Ubiquitin-conjugating enzyme E2D 4 (putative)
type: ProteinReference
xref: uniprot F6VCY8 340
organism: Xenopus tropicalis

uniprot Q9LIY1 515
type: UnificationXref
id: Q9LIY1
db: uniprot

uniprot Q7KMP8 132
type: UnificationXref
id: Q7KMP8
db: uniprot

uniprot Q9SSB5 165
type: UnificationXref
id: Q9SSB5
db: uniprot

uniprot O35226 74
type: UnificationXref
id: O35226
db: uniprot

uniprot F1PDI6 326
type: UnificationXref
id: F1PDI6
db: uniprot

uniprot Q9P6I1 518
type: UnificationXref
id: Q9P6I1
db: uniprot

uniprot E2QXE6 317
type: UnificationXref
id: E2QXE6
db: uniprot

26S proteasome regulatory particle triple-A ATPase subunit6
type: ProteinReference
xref: uniprot Q7GCH3 131
organism: Oryza sativa

E2
type: ProteinReference
xref: P01491
standard name: Ubiquitin-conjugating enzyme E2
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: Ubiquitin-conjugating enzyme E2 Synonym: Synonym not specified Accession: P01491
comment: ENTITY_REFERENCE_ID_DESC=Ubiquitin proteasome pathway.PROTEIN.GENERIC.E2
member entity reference: Ubiquitin-conjugating enzyme E2 A
member entity reference: UBE2N isoform 2
member entity reference: Ubiquitin-conjugating enzyme E2, putative
member entity reference: AGAP000145-PA
member entity reference: Predicted protein
member entity reference: Ubiquitin-conjugating enzyme E2 G2
member entity reference: Uncharacterized protein
member entity reference: Ubiquitin-conjugating enzyme E2 14
member entity reference: Ubiquitin-conjugating enzyme E2 E3
member entity reference: Ubiquitin-conjugating enzyme E2 K
member entity reference: Os09g0297100 protein
member entity reference: Ubiquitin conjugating enzyme E2 B
member entity reference: Ubiquitin protein ligase, putative
member entity reference: Ubiquitin-conjugating enzyme E2 D1
member entity reference: Ubiquitin-conjugating enzyme E2 G1
member entity reference: Ubiquitin-conjugating enzyme E2 D4
member entity reference: Ubiquitin-conjugating enzyme E2 L3
member entity reference: Ubiquitin conjugating enzyme E2 V2
member entity reference: Ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
member entity reference: Ubiquitin-conjugating enzyme E2 B
member entity reference: Ubiquitin-conjugating enzyme E2D 1a
member entity reference: Ubiquitin-conjugating enzyme E2 S
member entity reference: Ubiquitin-conjugating enzyme E2 2
member entity reference: Putative ubiquitin-conjugating enzyme e2
member entity reference: Ubiquitin-conjugating enzyme E2
member entity reference: Ubiquitin-conjugating enzyme E2 D3
member entity reference: Ubiquitin-conjugating enzyme
member entity reference: Ubiquitin-conjugating enzyme E2 27
member entity reference: Ubiquitin-conjugating enzyme E2 7
member entity reference: Protein CBR-LET-70
member entity reference: Protein CBR-UBC-20
member entity reference: Ubiquitin-conjugating enzyme E2-18 kDa
member entity reference: Ubiquitin-conjugating enzyme E2 1
member entity reference: Probable ubiquitin-conjugating enzyme E2 18
member entity reference: Protein PEROXIN-4
member entity reference: UBE2D2 isoform 7
member entity reference: Ubiquitin-conjugating enzyme E2 V2
member entity reference: Ubiquitin-conjugating enzyme E2 C
member entity reference: AGAP003857-PA
member entity reference: Os01g0839700 protein
member entity reference: Ubiquitin-conjugating enzyme E2 8
member entity reference: Ubiquitin-conjugating enzyme E2 E2
member entity reference: Ubiquitin conjugating enzyme E2 N like (gene/pseudogene)
member entity reference: Ubiquitin/ISG15-conjugating enzyme E2 L6
member entity reference: Ubiquitin-conjugating enzyme E2-17 kDa
member entity reference: Ubiquitin protein ligase

uniprot Q7M767 481
type: UnificationXref
id: Q7M767
db: uniprot

uniprot F1MLS5 199
type: UnificationXref
id: F1MLS5
db: uniprot

uniprot Q7PGR3 605
type: UnificationXref
id: Q7PGR3
db: uniprot

26S proteasome non-ATPase regulatory subunit 1
type: ProteinReference
xref: uniprot F1PX57 48
organism: Canis lupus familiaris

uniprot F1PB35 205
type: UnificationXref
id: F1PB35
db: uniprot

ncbitaxon 7739 37
type: UnificationXref
id: 7739
db: ncbitaxon

Probable ubiquitin-conjugating enzyme e2-17 kDa
type: ProteinReference
xref: uniprot Q9GNC1 514
organism: Leishmania major

uniprot A0A1L1RZV0 279
type: UnificationXref
id: A0A1L1RZV0
db: uniprot

uniprot Q9FJC9 152
type: UnificationXref
id: Q9FJC9
db: uniprot

uniprot O13685 386
type: UnificationXref
id: O13685
db: uniprot

26S proteasome regulatory subunit RPN1
type: ProteinReference
xref: uniprot P38764 93
organism: Saccharomyces cerevisiae

26S proteasome regulatory subunit 8 homolog A
type: ProteinReference
xref: uniprot Q9C5U3 151
organism: Arabidopsis thaliana

Oryza sativa
type: BioSource
xref: ncbitaxon 39947 35

uniprot Q8W425 145
type: UnificationXref
id: Q8W425
db: uniprot

26S proteasome regulatory subunit 6A homolog
type: ProteinReference
xref: uniprot P46465 96
organism: Oryza sativa

CATALYSIS
type: Catalysis
controlled: STATE_TRANSITION_LEFT__E2-_Protein_target-RIGHT__E2-_Protein_target-_r12
controller: E3

26S proteasome regulatory subunit 4 homolog
type: ProteinReference
xref: uniprot P46466 97
organism: Oryza sativa

Protein PEROXIN-4
type: ProteinReference
xref: uniprot Q8LGF7 495
organism: Arabidopsis thaliana

PTHR11254:SF293
type: RelationshipXref
id: PTHR11254:SF293
db: PANTHER Family
relationship type: By Homology

NEDD4-like E3 ubiquitin-protein ligase WWP1
type: ProteinReference
xref: uniprot Q8BZZ3 260
organism: Mus musculus

Ubiquitin-protein ligase E3A
type: ProteinReference
xref: uniprot O08759 234
organism: Mus musculus

Uncharacterized protein
type: ProteinReference
xref: uniprot A7F3F7 588
organism: Sclerotinia sclerotiorum

uniprot Q7XIC8 487
type: UnificationXref
id: Q7XIC8
db: uniprot

uniprot Q8VWK0 142
type: UnificationXref
id: Q8VWK0
db: uniprot

uniprot Q1K827 252
type: UnificationXref
id: Q1K827
db: uniprot

uniprot Q9SLE4 522
type: UnificationXref
id: Q9SLE4
db: uniprot

uniprot O04019 69
type: UnificationXref
id: O04019
db: uniprot

Pi
type: SmallMolecule
cellular location: cytosol
comment: SPECIES_TYPE=ION

SMAD-specific E3 ubiquitin protein ligase 2
type: ProteinReference
xref: PTHR11254:SF300
xref: uniprot F1M3F2 196
organism: Rattus norvegicus

26S proteasome non-ATPase regulatory subunit 14
type: ProteinReference
xref: PTHR10410:SF5
xref: uniprot O00487 67
organism: Homo sapiens

uniprot C3ZGJ2 309
type: UnificationXref
id: C3ZGJ2
db: uniprot

uniprot P31254 561
type: UnificationXref
id: P31254
db: uniprot

Anopheles gambiae
type: BioSource
xref: ncbitaxon 7165 135

Uncharacterized protein
type: ProteinReference
xref: uniprot D3ZYE1 313
organism: Rattus norvegicus

Uncharacterized protein
type: ProteinReference
xref: uniprot E1BCU1 190
organism: Bos taurus

PSMD14 isoform 1
type: ProteinReference
xref: uniprot H2QIW0 63
xref: PTHR10410:SF5
organism: Pan troglodytes

uniprot Q7PXH7 134
type: UnificationXref
id: Q7PXH7
db: uniprot

uniprot Q9HAU4 268
type: UnificationXref
id: Q9HAU4
db: uniprot

uniprot H2QIW0 63
type: UnificationXref
id: H2QIW0
db: uniprot

uniprot F6TLE0 541
type: UnificationXref
id: F6TLE0
db: uniprot

uniprot A0A1D5RFZ4 278
type: UnificationXref
id: A0A1D5RFZ4
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F6SU17 336
organism: Monodelphis domestica

uniprot Q6PEH5 476
type: UnificationXref
id: Q6PEH5
db: uniprot

Protein target
type: Protein
feature: Lysine Protein target s15 a22 rs1
cellular location: cytosol
comment: SPECIES_TYPE=PROTEIN

uniprot O97241 394
type: UnificationXref
id: O97241
db: uniprot

UBE2D1 isoform 1
type: ProteinReference
xref: uniprot H2Q1X5 367
organism: Pan troglodytes

uniprot F6UEX6 213
type: UnificationXref
id: F6UEX6
db: uniprot

NEDD8-activating enzyme E1 catalytic subunit
type: ProteinReference
xref: uniprot Q8TBC4 574
organism: Homo sapiens

uniprot E1BCU1 190
type: UnificationXref
id: E1BCU1
db: uniprot

Ubiquitin protein ligase E3B
type: ProteinReference
xref: uniprot E2QUU3 191
organism: Canis lupus familiaris

uniprot F7A2Q4 215
type: UnificationXref
id: F7A2Q4
db: uniprot

uniprot F1MYE6 200
type: UnificationXref
id: F1MYE6
db: uniprot

MODIFICATION FEATURE ubiquitinated
type: SequenceModificationVocabulary
comment: DATA_SOURCE=CellDesigner

uniprot Q6GL05 472
type: UnificationXref
id: Q6GL05
db: uniprot

uniprot Q1RML1 447
type: UnificationXref
id: Q1RML1
db: uniprot

Probable 26S proteasome regulatory subunit rpn3
type: ProteinReference
xref: PTHR10758:SF2
xref: uniprot O42897 77
organism: Schizosaccharomyces pombe

26S proteasome non-ATPase regulatory subunit 2
type: ProteinReference
xref: uniprot Q8VDM4 141
organism: Mus musculus

Protein CBR-UBC-20
type: ProteinReference
xref: uniprot A8XMM5 295
organism: Caenorhabditis briggsae

Ubiquitin-conjugating enzyme E2 8
type: ProteinReference
xref: uniprot P35131 404
organism: Arabidopsis thaliana

PTHR24068:SF116
type: RelationshipXref
id: PTHR24068:SF116
db: PANTHER Family
relationship type: By Homology

uniprot Q16763 445
type: UnificationXref
id: Q16763
db: uniprot

Ubiquitin-conjugating enzyme E2 11
type: ProteinReference
xref: uniprot P35134 406
organism: Arabidopsis thaliana

Ubiquitin-conjugating enzyme E2 10
type: ProteinReference
xref: uniprot P35133 405
organism: Arabidopsis thaliana

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A1D5QQB8 274
xref: PTHR24068:SF67
organism: Macaca mulatta

E3 ubiquitin-protein ligase
type: ProteinReference
xref: uniprot E2RSE2 195
organism: Canis lupus familiaris

NEDD8-activating enzyme E1 catalytic subunit isoform 1
type: ProteinReference
xref: uniprot F7FCV2 549
organism: Macaca mulatta

uniprot Q8W423 144
type: UnificationXref
id: Q8W423
db: uniprot

uniprot F7G2B2 359
type: UnificationXref
id: F7G2B2
db: uniprot

uniprot P87048 102
type: UnificationXref
id: P87048
db: uniprot

ncbitaxon 6238 293
type: UnificationXref
id: 6238
db: ncbitaxon

uniprot Q6H7I5 473
type: UnificationXref
id: Q6H7I5
db: uniprot

uniprot Q5B963 118
type: UnificationXref
id: Q5B963
db: uniprot

uniprot F7DI62 217
type: UnificationXref
id: F7DI62
db: uniprot

uniprot A9SDW9 300
type: UnificationXref
id: A9SDW9
db: uniprot

uniprot Q9TZ69 524
type: UnificationXref
id: Q9TZ69
db: uniprot

uniprot A0A0P0V9Q4 271
type: UnificationXref
id: A0A0P0V9Q4
db: uniprot

uniprot P0DKJ9 90
type: UnificationXref
id: P0DKJ9
db: uniprot

uniprot A9TIG8 302
type: UnificationXref
id: A9TIG8
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A1D5QXE9 277
organism: Macaca mulatta

Ubiquitin-conjugating enzyme E2 variant 2
type: ProteinReference
xref: uniprot Q7M767 481
organism: Rattus norvegicus

E3 ubiquitin-protein ligase NEDD4
type: ProteinReference
xref: uniprot Q62940 256
organism: Rattus norvegicus

uniprot Q3MHP1 456
type: UnificationXref
id: Q3MHP1
db: uniprot

Ubiquitin-conjugating enzyme E2 2
type: ProteinReference
xref: uniprot P35129 403
organism: Caenorhabditis elegans

uniprot A7MBA2 17
type: UnificationXref
id: A7MBA2
db: uniprot

uniprot G2HEI6 223
type: UnificationXref
id: G2HEI6
db: uniprot

Ube2n protein
type: ProteinReference
xref: uniprot Q803J2 490
organism: Danio rerio

Ubiquitin-conjugating enzyme E2 13
type: ProteinReference
xref: uniprot O13685 386
organism: Schizosaccharomyces pombe

Ubiquitin conjugating enzyme E2 D1
type: ProteinReference
xref: uniprot J9NTA2 379
organism: Canis lupus familiaris

26S proteasome non-ATPase regulatory subunit 1
type: ProteinReference
xref: uniprot Q99460 149
organism: Homo sapiens

Ubiquitin-conjugating enzyme E2 1
type: ProteinReference
xref: uniprot O74810 391
organism: Schizosaccharomyces pombe

uniprot K7BL13 231
type: UnificationXref
id: K7BL13
db: uniprot

NEDD8-activating enzyme E1 regulatory subunit AXL
type: ProteinReference
xref: uniprot Q9ZV69 585
organism: Arabidopsis thaliana

Ubiquitin conjugating enzyme E2 K
type: ProteinReference
xref: uniprot E2R6W9 192
organism: Canis lupus familiaris

uniprot P63147 434
type: UnificationXref
id: P63147
db: uniprot

uniprot F1QEG9 208
type: UnificationXref
id: F1QEG9
db: uniprot

Schizosaccharomyces pombe
type: BioSource
xref: ncbitaxon 284812 78

E3 ubiquitin-protein ligase
type: ProteinReference
xref: uniprot F1MGQ5 198
organism: Bos taurus

Ashbya gossypii
type: BioSource
xref: ncbitaxon 284811 479

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A1D5PYT9 177
organism: Gallus gallus

Proteasome 26S subunit, non-ATPase 7
type: ProteinReference
xref: uniprot A0A2R8Q5H4 11
organism: Danio rerio

uniprot H9FUJ1 228
type: UnificationXref
id: H9FUJ1
db: uniprot

uniprot A0A1D5PYT9 177
type: UnificationXref
id: A0A1D5PYT9
db: uniprot

uniprot P40016 95
type: UnificationXref
id: P40016
db: uniprot

26S proteasome non-ATPase regulatory subunit 13 homolog B
type: ProteinReference
xref: uniprot Q8GYA6 137
organism: Arabidopsis thaliana

uniprot K7D8I3 232
type: UnificationXref
id: K7D8I3
db: uniprot

Ubiquitin-conjugating enzyme E2A (RAD6 homolog)
type: ProteinReference
xref: uniprot Q789K9 480
organism: Danio rerio

uniprot Q9Z255 529
type: UnificationXref
id: Q9Z255
db: uniprot

uniprot Q9W6F3 526
type: UnificationXref
id: Q9W6F3
db: uniprot

uniprot P0DI13 559
type: UnificationXref
id: P0DI13
db: uniprot

E2
type: Protein
entity reference: E2
feature: SH E2 s2 a2 rs1
cellular location: cytosol
comment: SPECIES_TYPE=PROTEIN

Batrachochytrium dendrobatidis
type: BioSource
xref: ncbitaxon 684364 329

Uncharacterized protein
type: ProteinReference
xref: uniprot F6Z075 345
organism: Monodelphis domestica

GO GO:0005829 2
type: UnificationXref
id: GO:0005829
db: GO

PTHR24068:SF170
type: RelationshipXref
id: PTHR24068:SF170
db: PANTHER Family
relationship type: By Homology

Ubiquitin-conjugating enzyme E2 A,-like
type: ProteinReference
xref: uniprot Q803M4 491
organism: Danio rerio

Probable E3 ubiquitin-protein ligase HUL4
type: ProteinReference
xref: uniprot P40985 239
organism: Saccharomyces cerevisiae

uniprot Q803M4 491
type: UnificationXref
id: Q803M4
db: uniprot

uniprot Q6AXQ0 571
type: UnificationXref
id: Q6AXQ0
db: uniprot

26S proteasome regulatory subunit RPN3
type: ProteinReference
xref: PTHR10758:SF2
xref: uniprot P40016 95
organism: Saccharomyces cerevisiae

uniprot A0AVT1 532
type: UnificationXref
id: A0AVT1
db: uniprot

uniprot P51665 99
type: UnificationXref
id: P51665
db: uniprot

uniprot O74894 597
type: UnificationXref
id: O74894
db: uniprot

uniprot Q28EY6 449
type: UnificationXref
id: Q28EY6
db: uniprot

SUMO-activating enzyme subunit 2
type: ProteinReference
xref: uniprot H2QG08 551
organism: Pan troglodytes

Ubiquitin like modifier activating enzyme 6
type: ProteinReference
xref: uniprot E2R529 536
organism: Canis lupus familiaris

uniprot H3EGL4 375
type: UnificationXref
id: H3EGL4
db: uniprot

uniprot O42897 77
type: UnificationXref
id: O42897
db: uniprot

ncbitaxon 39947 35
type: UnificationXref
id: 39947
db: ncbitaxon

Homo sapiens
type: BioSource
xref: ncbitaxon 9606 68

Proteasome 26S subunit, non-ATPase 14
type: ProteinReference
xref: PTHR10410:SF5
xref: uniprot F7AZ85 54
organism: Ornithorhynchus anatinus

uniprot Q9DBH0 265
type: UnificationXref
id: Q9DBH0
db: uniprot

uniprot Q9SEI4 162
type: UnificationXref
id: Q9SEI4
db: uniprot

Predicted protein
type: ProteinReference
xref: uniprot A9T0I0 27
organism: Physcomitrella patens

Ubiquitin-conjugating enzyme E2 D3
type: ProteinReference
xref: uniprot Q3ZCF7 457
organism: Bos taurus

By Homology
type: RelationshipTypeVocabulary

ncbitaxon 7955 12
type: UnificationXref
id: 7955
db: ncbitaxon

uniprot K7BGN1 229
type: UnificationXref
id: K7BGN1
db: uniprot

AGAP003857-PA
type: ProteinReference
xref: uniprot Q7QFT1 483
organism: Anopheles gambiae

uniprot Q5JXB2 465
type: UnificationXref
id: Q5JXB2
db: uniprot

uniprot P46466 97
type: UnificationXref
id: P46466
db: uniprot

Ubiquitin-conjugating enzyme E2 K
type: ProteinReference
xref: uniprot F6UEX6 213
organism: Macaca mulatta

uniprot A8XA84 294
type: UnificationXref
id: A8XA84
db: uniprot

19S proteasome s18 sa2 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: 19S proteasome
stoichiometric coefficient: 1.0

Ubiquitin protein ligase E3C
type: ProteinReference
xref: uniprot F6PLU9 209
organism: Ornithorhynchus anatinus

26S protease regulatory subunit 6B isoform 1
type: ProteinReference
xref: uniprot F7HIL8 596
organism: Macaca mulatta

uniprot A2VE14 533
type: UnificationXref
id: A2VE14
db: uniprot

Predicted protein
type: ProteinReference
xref: uniprot A9SCD7 298
organism: Physcomitrella patens

uniprot O00487 67
type: UnificationXref
id: O00487
db: uniprot

Predicted protein
type: ProteinReference
xref: uniprot A9TJC3 30
organism: Physcomitrella patens

uniprot F1N3W8 201
type: UnificationXref
id: F1N3W8
db: uniprot

Strongylocentrotus purpuratus
type: BioSource
xref: ncbitaxon 7668 172

uniprot F1PRW0 47
type: UnificationXref
id: F1PRW0
db: uniprot

uniprot A9REE1 22
type: UnificationXref
id: A9REE1
db: uniprot

Ubiquitin-like modifier-activating enzyme 1
type: ProteinReference
xref: uniprot F1RCA1 540
organism: Danio rerio

Os02g0325100 protein
type: ProteinReference
xref: uniprot Q6Z875 130
organism: Oryza sativa

uniprot Q9SIV2 163
type: UnificationXref
id: Q9SIV2
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot Q0TVC0 103
organism: Phaeosphaeria nodorum

Uncharacterized protein
type: ProteinReference
xref: uniprot E1BZJ2 315
organism: Gallus gallus

uniprot Q7SDQ8 136
type: UnificationXref
id: Q7SDQ8
db: uniprot

26S proteasome non-ATPase regulatory subunit 13
type: ProteinReference
xref: PTHR10539:SF0
xref: uniprot Q5E964 121
organism: Bos taurus

uniprot E2RSE2 195
type: UnificationXref
id: E2RSE2
db: uniprot

Os05g0182500 protein
type: ProteinReference
xref: uniprot Q0DK90 440
organism: Oryza sativa

E3 ubiquitin-protein ligase pub1
type: ProteinReference
xref: uniprot Q92462 262
organism: Schizosaccharomyces pombe

uniprot F7HBX8 363
type: UnificationXref
id: F7HBX8
db: uniprot

uniprot K7CGF3 382
type: UnificationXref
id: K7CGF3
db: uniprot

uniprot Q8WZY4 146
type: UnificationXref
id: Q8WZY4
db: uniprot

uniprot A0A3Q1MXC6 183
type: UnificationXref
id: A0A3Q1MXC6
db: uniprot

uniprot H2QNV3 64
type: UnificationXref
id: H2QNV3
db: uniprot

uniprot A4IFN7 186
type: UnificationXref
id: A4IFN7
db: uniprot

Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14
type: ProteinReference
xref: uniprot Q4V8E2 117
xref: PTHR10410:SF5
organism: Rattus norvegicus

PTHR10223:SF0
type: RelationshipXref
id: PTHR10223:SF0
db: PANTHER Family
relationship type: By Homology

PTHR10223:SF7
type: RelationshipXref
id: PTHR10223:SF7
db: PANTHER Family
relationship type: By Homology

26S proteasome regulatory subunit 6B homolog
type: ProteinReference
xref: uniprot P33298 598
organism: Saccharomyces cerevisiae

uniprot Q9SEI2 160
type: UnificationXref
id: Q9SEI2
db: uniprot

PARTICIPANT STOICHIOMETRY r10 615
type: Stoichiometry
physical entity: Complex (ubiquitin/E1)
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r10 617
type: Stoichiometry
physical entity: AMP
stoichiometric coefficient: 1.0

PARTICIPANT STOICHIOMETRY r10 616
type: Stoichiometry
physical entity: E1
stoichiometric coefficient: 1.0

Uncharacterized protein
type: ProteinReference
xref: uniprot E9I205 324
organism: Daphnia pulex

Complex (26S proteasome/19S proteasome)
type: Complex
component stoichiometry: 19S proteasome s18 sa2 STOICHIOMETRY ID COMPLEX
component stoichiometry: 26S proteasome s16 sa1 STOICHIOMETRY ID COMPLEX
component: 19S proteasome
component: 26S proteasome
feature: COMPLEX BINDING FEATURE s7 a7 608
feature: COMPLEX BINDING FEATURE s7 a7 606
cellular location: cytosol

Ubiquitin-conjugating enzyme E2 E2
type: ProteinReference
xref: uniprot Q91W82 502
organism: Mus musculus

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A1D5Q8Y9 178
organism: Macaca mulatta

Ubiquitin-like modifier-activating enzyme 6
type: ProteinReference
xref: uniprot A0AVT1 532
organism: Homo sapiens

uniprot H2R4I1 374
type: UnificationXref
id: H2R4I1
db: uniprot

Dictyostelium discoideum
type: BioSource
xref: ncbitaxon 44689 493

Os05g0371200 protein
type: ProteinReference
xref: PTHR10410:SF5
xref: uniprot Q60EW3 125
organism: Oryza sativa

uniprot A7EC83 288
type: UnificationXref
id: A7EC83
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F6TQE0 337
organism: Monodelphis domestica

Uncharacterized protein
type: ProteinReference
xref: uniprot F7CHT9 56
xref: PTHR10410:SF5
organism: Monodelphis domestica

Ubiquitin-conjugating enzyme E2 S
type: ProteinReference
xref: uniprot B5DFI8 305
organism: Rattus norvegicus

uniprot O23717 72
type: UnificationXref
id: O23717
db: uniprot

uniprot E1BZJ2 315
type: UnificationXref
id: E1BZJ2
db: uniprot

uniprot J9NS22 378
type: UnificationXref
id: J9NS22
db: uniprot

uniprot Q1RMX2 448
type: UnificationXref
id: Q1RMX2
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot Q5ZLH8 467
organism: Gallus gallus

Trypanosoma brucei
type: BioSource
xref: ncbitaxon 185431 463

E3
type: ProteinReference
xref: P01490
standard name: Ubiquitin protein ligase E3
comment: ENTITY_REFERENCE_PROTEIN_TYPE=GENERIC
comment: ENTITY_REFERENCE_NOTES= Long Name: Ubiquitin protein ligase E3 Synonym: E6AP Accession: P01490
comment: ENTITY_REFERENCE_ID_DESC=Ubiquitin proteasome pathway.PROTEIN.GENERIC.E3
member entity reference: E3 ubiquitin-protein ligase pub2
member entity reference: E3 ubiquitin-protein ligase
member entity reference: Ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome)
member entity reference: E3 ubiquitin-protein ligase SMURF1
member entity reference: E3 ubiquitin-protein ligase pub3
member entity reference: E3 ubiquitin-protein ligase ptr1
member entity reference: Uncharacterized protein
member entity reference: UBE3A protein
member entity reference: Ubiquitin protein ligase E3B
member entity reference: Ubiquitin-like modifier-activating enzyme 7
member entity reference: Ubiquitin-conjugating enzyme E2 K
member entity reference: Probable E3 ubiquitin-protein ligase mug30
member entity reference: Ubiquitin-protein ligase E3A
member entity reference: Ubiquitin protein ligase E3A
member entity reference: E3 ubiquitin-protein ligase NEDD4
member entity reference: UBE3B isoform 1
member entity reference: UBA7 isoform 1
member entity reference: Huntingtin interacting protein 2 (Predicted), isoform CRA_a
member entity reference: E3 ubiquitin-protein ligase Mdm2
member entity reference: MDM2 proto-oncogene
member entity reference: SMAD-specific E3 ubiquitin protein ligase 2
member entity reference: E3 ubiquitin-protein ligase pub1
member entity reference: Ubiquitin-like modifier-activating enzyme 1
member entity reference: Ubiquitin protein ligase E3C
member entity reference: Ubiquitin-conjugating enzyme E2 4
member entity reference: SMAD specific E3 ubiquitin protein ligase 2
member entity reference: E3 ubiquitin-protein ligase SMURF2
member entity reference: Ubiquitin-protein ligase E3C
member entity reference: E3 ubiquitin-protein ligase Itchy
member entity reference: E3 ubiquitin-protein ligase Itchy homolog
member entity reference: Ubiquitin conjugating enzyme
member entity reference: UBE3A isoform 14
member entity reference: UBE3C isoform 1
member entity reference: Ubiquitin-protein ligase E3B
member entity reference: NEDD4-like E3 ubiquitin-protein ligase WWP2
member entity reference: Ubiquitin-conjugating enzyme E2 6
member entity reference: Ubiquitin conjugating enzyme E2 K

uniprot Q5ZL59 466
type: UnificationXref
id: Q5ZL59
db: uniprot

uniprot F7HPB0 222
type: UnificationXref
id: F7HPB0
db: uniprot

uniprot F7EYF1 219
type: UnificationXref
id: F7EYF1
db: uniprot

uniprot F7HH32 364
type: UnificationXref
id: F7HH32
db: uniprot

26S proteasome regulatory subunit T4
type: ProteinReference
xref: uniprot Q7PXH7 134
organism: Anopheles gambiae

Nematostella vectensis
type: BioSource
xref: ncbitaxon 45351 19

Ubiquitin-conjugating enzyme E2
type: ProteinReference
xref: uniprot Q8VZX3 500
organism: Chlamydomonas reinhardtii

MGC97603 protein
type: ProteinReference
xref: uniprot Q5BJ72 120
organism: Xenopus tropicalis

Probable ubiquitin-conjugating enzyme E2 18
type: ProteinReference
xref: uniprot Q9FMM0 512
organism: Arabidopsis thaliana

Ubiquitin-conjugating enzyme E2-16 kDa
type: ProteinReference
xref: uniprot P15732 396
organism: Saccharomyces cerevisiae

Ubiquitin-conjugating enzyme E2 4
type: ProteinReference
xref: uniprot P15731 395
organism: Saccharomyces cerevisiae

uniprot Q57W45 462
type: UnificationXref
id: Q57W45
db: uniprot

E3 ubiquitin-protein ligase
type: ProteinReference
xref: uniprot K7BK39 230
organism: Pan troglodytes

Probable 26S proteasome regulatory subunit rpn7
type: ProteinReference
xref: uniprot Q10335 105
organism: Schizosaccharomyces pombe

E3 ubiquitin-protein ligase
type: ProteinReference
xref: PTHR11254:SF300
xref: uniprot F1N3W8 201
organism: Bos taurus

Uncharacterized protein
type: ProteinReference
xref: uniprot F6RKN5 210
organism: Macaca mulatta

uniprot A9T0I0 27
type: UnificationXref
id: A9T0I0
db: uniprot

E3 ubiquitin-protein ligase
type: ProteinReference
xref: uniprot Q4V8H7 254
organism: Rattus norvegicus

uniprot Q1K7R0 446
type: UnificationXref
id: Q1K7R0
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot F6TV67 338
organism: Macaca mulatta

uniprot F6Y9A7 595
type: UnificationXref
id: F6Y9A7
db: uniprot

uniprot Q5E964 121
type: UnificationXref
id: Q5E964
db: uniprot

uniprot F1M7B8 197
type: UnificationXref
id: F1M7B8
db: uniprot

uniprot E2RHN3 319
type: UnificationXref
id: E2RHN3
db: uniprot

E1 s6 sa4 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: E1
stoichiometric coefficient: 1.0

Ubiquitin-conjugating enzyme E2 D3
type: ProteinReference
xref: uniprot Q28EY6 449
organism: Xenopus tropicalis

ncbitaxon 6239 402
type: UnificationXref
id: 6239
db: ncbitaxon

SUMO-activating enzyme subunit 1A
type: ProteinReference
xref: uniprot Q8VY78 575
organism: Arabidopsis thaliana

uniprot F7FZL4 356
type: UnificationXref
id: F7FZL4
db: uniprot

26S proteasome regulatory subunit 6B homolog
type: ProteinReference
xref: uniprot O74894 597
organism: Schizosaccharomyces pombe

uniprot P43686 600
type: UnificationXref
id: P43686
db: uniprot

uniprot A0A2I3SGQ4 282
type: UnificationXref
id: A0A2I3SGQ4
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot E1C9E7 316
organism: Gallus gallus

uniprot Q9EQX9 510
type: UnificationXref
id: Q9EQX9
db: uniprot

Ubiquitin protein ligase E3A
type: ProteinReference
xref: uniprot F1M7B8 197
organism: Rattus norvegicus

uniprot A9RJ42 23
type: UnificationXref
id: A9RJ42
db: uniprot

uniprot E9GN25 43
type: UnificationXref
id: E9GN25
db: uniprot

Ubiquitin-conjugating enzyme, putative
type: ProteinReference
xref: uniprot O77397 393
organism: Plasmodium falciparum

Ubiquitin-conjugating enzyme E2 27
type: ProteinReference
xref: uniprot Q9FI61 511
organism: Arabidopsis thaliana

uniprot Q28I82 451
type: UnificationXref
id: Q28I82
db: uniprot

Os01g0839700 protein
type: ProteinReference
xref: uniprot Q943L1 504
organism: Oryza sativa

uniprot P61077 422
type: UnificationXref
id: P61077
db: uniprot

uniprot F0ZYD1 593
type: UnificationXref
id: F0ZYD1
db: uniprot

uniprot Q756T0 478
type: UnificationXref
id: Q756T0
db: uniprot

ubiquitin s5 sa3 STOICHIOMETRY ID COMPLEX
type: Stoichiometry
physical entity: ubiquitin
stoichiometric coefficient: 1.0

uniprot F7GU37 361
type: UnificationXref
id: F7GU37
db: uniprot

STATE_TRANSITION_LEFT__E2-_E1-RIGHT__E1-_E2-_r11
type: BiochemicalReaction
conversion direction: LEFT_TO_RIGHT
xref: STATE TRANSITION
participant stoichiometry: PARTICIPANT STOICHIOMETRY r11 635
participant stoichiometry: PARTICIPANT STOICHIOMETRY r11 634
participant stoichiometry: PARTICIPANT STOICHIOMETRY r11 633
participant stoichiometry: PARTICIPANT STOICHIOMETRY r11 636
left: E1
left: E2
interaction type: STATE_TRANSITION
right: E2
right: E1

SUMO-activating enzyme subunit 1
type: ProteinReference
xref: uniprot Q9R1T2 580
organism: Mus musculus

uniprot F1PBV3 206
type: UnificationXref
id: F1PBV3
db: uniprot

uniprot Q10335 105
type: UnificationXref
id: Q10335
db: uniprot

Ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
type: ProteinReference
xref: uniprot B0S6A7 304
organism: Danio rerio

Os01g0273100 protein
type: ProteinReference
xref: uniprot Q9LIY1 515
organism: Oryza sativa

Ubiquitin-activating enzyme E1 2
type: ProteinReference
xref: uniprot P92974 564
organism: Arabidopsis thaliana

Predicted protein
type: ProteinReference
xref: uniprot A9S453 24
organism: Physcomitrella patens

Proteasome subunit beta type-5-A
type: ProteinReference
xref: uniprot O23717 72
organism: Arabidopsis thaliana

Uncharacterized protein
type: ProteinReference
xref: uniprot F7BSZ9 546
organism: Monodelphis domestica

STATE_TRANSITION
type: InteractionVocabulary

uniprot A9RXP4 297
type: UnificationXref
id: A9RXP4
db: uniprot

Ubiquitin-conjugating enzyme E2 C
type: ProteinReference
xref: uniprot Q9D1C1 508
organism: Mus musculus

ubiquitin
type: SmallMolecule
feature: COMPLEX PARTICIPANT BINDING FEATURE s5 sa3 611
cellular location: cytosol
comment: SPECIES_TYPE=SIMPLE_MOLECULE

uniprot A7RQF7 18
type: UnificationXref
id: A7RQF7
db: uniprot

uniprot A7RXR8 290
type: UnificationXref
id: A7RXR8
db: uniprot

uniprot Q5BJ72 120
type: UnificationXref
id: Q5BJ72
db: uniprot

uniprot F1NJU6 204
type: UnificationXref
id: F1NJU6
db: uniprot

Ubiquitin-conjugating enzyme E2 N
type: ProteinReference
xref: uniprot H9FZA7 377
organism: Macaca mulatta

uniprot Q7KSM5 572
type: UnificationXref
id: Q7KSM5
db: uniprot

uniprot Q9CUN6 264
type: UnificationXref
id: Q9CUN6
db: uniprot

Candida albicans
type: BioSource
xref: ncbitaxon 237561 390

uniprot Q0TVC0 103
type: UnificationXref
id: Q0TVC0
db: uniprot

26S proteasome regulatory subunit S10B homolog B
type: ProteinReference
xref: uniprot Q9MAK9 156
organism: Arabidopsis thaliana

uniprot Q9NPD8 517
type: UnificationXref
id: Q9NPD8
db: uniprot

Ubiquitin-conjugating enzyme E2-17 kDa
type: ProteinReference
xref: uniprot P25867 400
organism: Drosophila melanogaster

uniprot A9SCD7 298
type: UnificationXref
id: A9SCD7
db: uniprot

Ubiquitin-conjugating enzyme E2 8
type: ProteinReference
xref: uniprot Q9P7R4 519
organism: Schizosaccharomyces pombe

uniprot Q9Y818 528
type: UnificationXref
id: Q9Y818
db: uniprot

Predicted protein
type: ProteinReference
xref: uniprot A9SCM3 299
organism: Physcomitrella patens

Uncharacterized protein
type: ProteinReference
xref: uniprot F7FZL4 356
organism: Monodelphis domestica

uniprot H2QWD9 225
type: UnificationXref
id: H2QWD9
db: uniprot

Ubiquitin conjugating enzyme
type: ProteinReference
xref: uniprot Q1K827 252
organism: Neurospora crassa

SUMO-activating enzyme subunit 2
type: ProteinReference
xref: uniprot F6TLE0 541
organism: Macaca mulatta

26S proteasome non-ATPase regulatory subunit 2
type: ProteinReference
xref: uniprot F7CS21 58
organism: Xenopus tropicalis

uniprot A9SRU1 26
type: UnificationXref
id: A9SRU1
db: uniprot

Predicted protein
type: ProteinReference
xref: uniprot A9RJ42 23
organism: Physcomitrella patens

uniprot Q803J2 490
type: UnificationXref
id: Q803J2
db: uniprot

Leishmania major
type: BioSource
xref: ncbitaxon 5664 116

Uncharacterized protein
type: ProteinReference
xref: uniprot A0A1D5RFZ4 278
organism: Macaca mulatta

uniprot F1QHE5 49
type: UnificationXref
id: F1QHE5
db: uniprot

uniprot Q9FXT8 153
type: UnificationXref
id: Q9FXT8
db: uniprot

cytosol
type: CellularLocationVocabulary
xref: GO GO:0005829 2

Ubiquitin-conjugating enzyme E
type: ProteinReference
xref: uniprot Q1K7R0 446
organism: Neurospora crassa

uniprot Q60EW3 125
type: UnificationXref
id: Q60EW3
db: uniprot

uniprot Q1K564 109
type: UnificationXref
id: Q1K564
db: uniprot

uniprot D3ZXS8 189
type: UnificationXref
id: D3ZXS8
db: uniprot

uniprot Q6L508 474
type: UnificationXref
id: Q6L508
db: uniprot

uniprot F6WGT0 52
type: UnificationXref
id: F6WGT0
db: uniprot

uniprot D6XHJ3 591
type: UnificationXref
id: D6XHJ3
db: uniprot

Phaeosphaeria nodorum
type: BioSource
xref: ncbitaxon 321614 104

uniprot Q7SXH5 485
type: UnificationXref
id: Q7SXH5
db: uniprot

26S proteasome regulatory subunit 6A homolog B
type: ProteinReference
xref: uniprot O04019 69
organism: Arabidopsis thaliana

19S proteasome
type: Protein
entity reference: 19S proteasome
feature: COMPLEX PARTICIPANT BINDING FEATURE s18 sa2 609
cellular location: cytosol
comment: SPECIES_TYPE=PROTEIN

Os02g0600100 protein
type: ProteinReference
xref: uniprot Q6K5H9 128
organism: Oryza sativa

E3 ubiquitin-protein ligase
type: ProteinReference
xref: uniprot A0A3Q1MXC6 183
organism: Bos taurus

uniprot Q4V8E2 117
type: UnificationXref
id: Q4V8E2
db: uniprot

Probable 26S proteasome regulatory subunit rpn6
type: ProteinReference
xref: uniprot Q9P7S2 158
xref: PTHR10678:SF2
organism: Schizosaccharomyces pombe

uniprot F6VFZ5 542
type: UnificationXref
id: F6VFZ5
db: uniprot

uniprot A9T1P2 29
type: UnificationXref
id: A9T1P2
db: uniprot

Uncharacterized protein
type: ProteinReference
xref: uniprot E9GN25 43
organism: Daphnia pulex

Ubiquitin-conjugating enzyme E2-17 kDa
type: ProteinReference
xref: uniprot P25153 399
organism: Drosophila melanogaster

Probable 26S proteasome regulatory subunit p27
type: ProteinReference
xref: uniprot O94393 88
organism: Schizosaccharomyces pombe

uniprot Q69TB0 468
type: UnificationXref
id: Q69TB0
db: uniprot

Ubiquitin-like modifier-activating enzyme atg7
type: ProteinReference
xref: uniprot Q94CD5 576
organism: Arabidopsis thaliana

uniprot O74440 81
type: UnificationXref
id: O74440
db: uniprot

uniprot F1ME38 538
type: UnificationXref
id: F1ME38
db: uniprot

uniprot B7Q0U7 308
type: UnificationXref
id: B7Q0U7
db: uniprot

uniprot A0A3Q1LXA9 530
type: UnificationXref
id: A0A3Q1LXA9
db: uniprot

ncbitaxon 9258 55
type: UnificationXref
id: 9258
db: ncbitaxon

SMAD specific E3 ubiquitin protein ligase 2
type: ProteinReference
xref: PTHR11254:SF300
xref: uniprot F1NJU6 204
organism: Gallus gallus

uniprot O24412 73
type: UnificationXref
id: O24412
db: uniprot

uniprot H2Q3P2 368
type: UnificationXref
id: H2Q3P2
db: uniprot

Ubiquitin-conjugating enzyme E2 D2B
type: ProteinReference
xref: uniprot Q6ZWY6 477
organism: Mus musculus

uniprot Q2TA10 453
type: UnificationXref
id: Q2TA10
db: uniprot

NEDD8-activating enzyme E1 catalytic subunit
type: ProteinReference
xref: uniprot Q99MI7 577
organism: Rattus norvegicus

Ubiquitin-conjugating enzyme E2, putative
type: ProteinReference
xref: uniprot O97241 394
organism: Plasmodium falciparum

uniprot A0A1D5Q067 272
type: UnificationXref
id: A0A1D5Q067
db: uniprot

ncbitaxon 9031 39
type: UnificationXref
id: 9031
db: ncbitaxon

Ubiquitin-like modifier-activating enzyme 3
type: ProteinReference
xref: uniprot F6VFZ5 542
organism: Xenopus tropicalis