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<![CDATA[
No pathway definition
]]>
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<body>
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<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  PKA
Synonym:  protein kinase A
Accession:  P04470
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p6</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="re11"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="c2" id="s24" name="SNARE Complex">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  SNARE Complex
Synonym:  Synonym not specified
Accession:  P04468
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p10</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="re10"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s43" name="K+">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  K+
Synonym:  Synonym not specified
Accession:  U05178
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>ION</celldesigner:class>
<celldesigner:name>K+</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="c5" id="s44" name="K+">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  K+
Synonym:  Synonym not specified
Accession:  U05178
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>ION</celldesigner:class>
<celldesigner:name>K+</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="c5" id="s45" name="depolarization">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  depolarization
Synonym:  Synonym not specified
Accession:  U05179
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PHENOTYPE</celldesigner:class>
<celldesigner:name>depolarization</celldesigner:name>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="re6"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="c5" id="s47" name="Complex(GTP/G-protein)">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long name not specified
Synonym:  Synonym not specified
Accession:  U05175
Heterodimer Member Info:  G-protein#PROTEIN#G-protein#P04467#Gi#;GTP#SIMPLE_MOLECULE#GTP#S04778##
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>GTP</celldesigner:name>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p11</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="re3"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="c2" id="s52" name="Dopamine">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Dopamine
Synonym:  Synonym not specified
Accession:  S04777
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Dopamine</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="c5" id="s48" name="K+ channel">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  K+ channel
Synonym:  Kcnk3,Potassium channel subfamily K member 3,Potassium channel subfamily K member 9,TASK-1,TASK-3,TWIK
Accession:  P04469
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p2</celldesigner:proteinReference>
<celldesigner:state>
<celldesigner:listOfModifications>
<celldesigner:modification residue="rs1" state="phosphorylated"/>
</celldesigner:listOfModifications>
</celldesigner:state>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="c5" id="s49" name="K+ channel">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  K+ channel
Synonym:  Kcnk3,Potassium channel subfamily K member 3,Potassium channel subfamily K member 9,TASK-1,TASK-3,TWIK
Accession:  P04469
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p2</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="re12"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
</listOfSpecies>
<listOfReactions>
<reaction id="re1" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s4</celldesigner:baseReactants>
<celldesigner:baseProducts>s14</celldesigner:baseProducts>
<celldesigner:editPoints>0.33333333333333304,-4.440892098500626E-16 0.6666666666666679,-4.440892098500626E-16</celldesigner:editPoints>
<celldesigner:listOfModification>
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</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s4">
<annotation>
<celldesigner:alias>a5</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s14">
<annotation>
<celldesigner:alias>a19</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s28">
<annotation>
<celldesigner:alias>a18</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="re2" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s33</celldesigner:baseReactants>
<celldesigner:baseProducts>s33</celldesigner:baseProducts>
<celldesigner:editPoints>0.33333333333333304,0.0 0.666666666666667,0.0</celldesigner:editPoints>
<celldesigner:listOfModification>
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</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s33">
<annotation>
<celldesigner:alias>a20</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s33">
<annotation>
<celldesigner:alias>a6</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s14">
<annotation>
<celldesigner:alias>a19</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="re3" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s28</celldesigner:baseReactants>
<celldesigner:baseProducts>s28</celldesigner:baseProducts>
<celldesigner:editPoints>0.33333333333333304,8.881784197001252E-16 0.6666666666666661,8.881784197001252E-16</celldesigner:editPoints>
<celldesigner:listOfModification>
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</celldesigner:listOfModification>
</annotation>
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<speciesReference species="s28">
<annotation>
<celldesigner:alias>a9</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s28">
<annotation>
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</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s47">
<annotation>
<celldesigner:alias>a31</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="re4" reversible="false">
<annotation>
<celldesigner:reactionType>HETERODIMER_ASSOCIATION</celldesigner:reactionType>
<celldesigner:baseReactants>s30,s13</celldesigner:baseReactants>
<celldesigner:baseProducts>s2</celldesigner:baseProducts>
<celldesigner:offset x="1.0" y="-10.0"/>
<celldesigner:editPoints>0.33333333333333304,-4.440892098500626E-16 0.666666666666667,-8.881784197001252E-16 0.33333333333333304,0.0 0.666666666666667,8.881784197001252E-16 0.33333333333333304,-1.1102230246251565E-16 0.6666666666666661,-5.551115123125783E-16 0.3333333333333337,0.3333333333333335</celldesigner:editPoints>
</annotation>
<listOfReactants>
<speciesReference species="s30">
<annotation>
<celldesigner:alias>a16</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s13">
<annotation>
<celldesigner:alias>a17</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s2">
<annotation>
<celldesigner:alias>a3</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
</reaction>
<reaction id="re6" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s24</celldesigner:baseReactants>
<celldesigner:baseProducts>s24</celldesigner:baseProducts>
<celldesigner:editPoints>0.33333333333333304,0.0 0.6666666666666665,0.0</celldesigner:editPoints>
<celldesigner:listOfModification>
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</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s24">
<annotation>
<celldesigner:alias>a14</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s24">
<annotation>
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</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s45">
<annotation>
<celldesigner:alias>a27</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="re10" reversible="false">
<annotation>
<celldesigner:reactionType>TRANSPORT</celldesigner:reactionType>
<celldesigner:baseReactants>s52</celldesigner:baseReactants>
<celldesigner:baseProducts>s30</celldesigner:baseProducts>
<celldesigner:offset x="5.0" y="-4.0"/>
<celldesigner:editPoints>-0.07547360335933861,0.9611625901639673 1.066491521110816,0.966318410695918</celldesigner:editPoints>
<celldesigner:listOfModification>
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</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s52">
<annotation>
<celldesigner:alias>a22</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s30">
<annotation>
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</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s24">
<annotation>
<celldesigner:alias>a13</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="re11" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s49</celldesigner:baseReactants>
<celldesigner:baseProducts>s48</celldesigner:baseProducts>
<celldesigner:editPoints>0.3333333333333339,0.0 0.666666666666667,-8.881784197001252E-16</celldesigner:editPoints>
<celldesigner:listOfModification>
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</celldesigner:listOfModification>
</annotation>
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<speciesReference species="s49">
<annotation>
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</annotation>
</speciesReference>
</listOfReactants>
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<annotation>
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</annotation>
</speciesReference>
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<listOfModifiers>
<modifierSpeciesReference species="s33">
<annotation>
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</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="re12" reversible="false">
<annotation>
<celldesigner:reactionType>TRANSPORT</celldesigner:reactionType>
<celldesigner:baseReactants>s44</celldesigner:baseReactants>
<celldesigner:baseProducts>s43</celldesigner:baseProducts>
<celldesigner:editPoints>0.3333333333333337,0.0 0.6666666666666667,-8.881784197001252E-16</celldesigner:editPoints>
<celldesigner:listOfModification>
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</annotation>
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<annotation>
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</speciesReference>
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<annotation>
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</speciesReference>
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<annotation>
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</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="re16" reversible="false">
<annotation>
<celldesigner:reactionType>DISSOCIATION</celldesigner:reactionType>
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<celldesigner:baseProducts>s47,s1</celldesigner:baseProducts>
<celldesigner:listOfReactantLinks>
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</celldesigner:listOfReactantLinks>
<celldesigner:listOfProductLinks>
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</celldesigner:listOfProductLinks>
<celldesigner:editPoints>0.33333333333333326,4.440892098500626E-16 0.6666666666666667,4.440892098500626E-16 0.3333333333333337,-8.881784197001252E-16 0.6666666666666665,-8.881784197001252E-16 0.3333333333333335,-1.1102230246251565E-16 0.6666666666666667,0.0 0.3333333333333335,0.3333333333333335</celldesigner:editPoints>
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<annotation>
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</speciesReference>
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<annotation>
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</speciesReference>
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<annotation>
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</speciesReference>
<speciesReference species="s1">
<annotation>
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</speciesReference>
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<annotation>
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</annotation>
</speciesReference>
</listOfProducts>
</reaction>
<reaction id="re17" reversible="false">
<annotation>
<celldesigner:reactionType>KNOWN_TRANSITION_OMITTED</celldesigner:reactionType>
<celldesigner:baseReactants>s48</celldesigner:baseReactants>
<celldesigner:baseProducts>s45</celldesigner:baseProducts>
<celldesigner:editPoints>0.33333333333333304,-1.6653345369377348E-16 0.6666666666666665,-1.6653345369377348E-16</celldesigner:editPoints>
</annotation>
<listOfReactants>
<speciesReference species="s48">
<annotation>
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</speciesReference>
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<listOfProducts>
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<annotation>
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</annotation>
</speciesReference>
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</reaction>
</listOfReactions>
</model>
</sbml>

