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The degradation of many polysaccharides and glycoproteins yields mannose, which is phosphorylated by hexokinase to generate mannose-6-phosphate. Mannose-6-phosphate is converted to fructose-6-phosphate, and then enters the glycolytic pathway or is converted to glucose-6-phosphate by the gluconeogenic pathway.
free text=Biochemiscal Pathways - An Atlas of Biochemistry and Molecular Biology Edited by Gerhard Michal
free text=Biochemistry by Voet and Voet
free text=Color Atlas of Biochemistry by Jan Koolman and Klaus-Heinrich Rohm
]]>
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Synonym:  Synonym not specified
Accession:  P03016
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p43</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s122" initialAmount="0.0" name="Glycoprotein">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Glycoprotein
Synonym:  Synonym not specified
Accession:  P03020
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p44</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s124" initialAmount="0.0" name="(Alginate)_sub_n+1_endsub">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  (Alginate)n+1
Synonym:  Synonym not specified
Accession:  S03799
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>(Alginate)_sub_n+1_endsub</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s125" initialAmount="0.0" name="GDP Mannose_br_6-dehydrogenase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  GDP Mannose 6-dehydrogenase
Synonym:  Synonym not specified
Accession:  P03021
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p45</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r59"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s126" initialAmount="0.0" name="Alginate synthase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Alginate synthase
Synonym:  Synonym not specified
Accession:  P03022
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p46</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r61"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s127" initialAmount="0.0" name="(Alginate)_sub_n_endsub">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  (Alginate)n
Synonym:  Synonym not specified
Accession:  S03805
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>(Alginate)_sub_n_endsub</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s128" initialAmount="0.0" name="GDP">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  GDP
Synonym:  Synonym not specified
Accession:  S03793
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>GDP</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
</listOfSpecies>
<listOfReactions>
<reaction id="r5" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s3</celldesigner:baseReactants>
<celldesigner:baseProducts>s4</celldesigner:baseProducts>
<celldesigner:listOfReactantLinks>
<celldesigner:reactantLink alias="a3" reactant="s3" targetLineIndex="-1,1"/>
</celldesigner:listOfReactantLinks>
<celldesigner:editPoints>0.33333333333333337,-4.440892098500626E-16 0.6666666666666669,0.0</celldesigner:editPoints>
</annotation>
<listOfReactants>
<speciesReference species="s3">
<annotation>
<celldesigner:alias>a3</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s3">
<annotation>
<celldesigner:alias>a3</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s4">
<annotation>
<celldesigner:alias>a2</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
</reaction>
<reaction id="r6" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s4</celldesigner:baseReactants>
<celldesigner:baseProducts>s6</celldesigner:baseProducts>
<celldesigner:offset x="1.0" y="0.0"/>
<celldesigner:editPoints>0.3333333333333335,-4.440892098500626E-16 0.6666666666666672,-8.881784197001252E-16</celldesigner:editPoints>
</annotation>
<listOfReactants>
<speciesReference species="s4">
<annotation>
<celldesigner:alias>a2</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s6">
<annotation>
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</annotation>
</speciesReference>
</listOfProducts>
</reaction>
<reaction id="r38" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s6</celldesigner:baseReactants>
<celldesigner:baseProducts>s71</celldesigner:baseProducts>
<celldesigner:editPoints>0.3333333333333335,8.881784197001252E-16 0.6666666666666679,0.0</celldesigner:editPoints>
</annotation>
<listOfReactants>
<speciesReference species="s6">
<annotation>
<celldesigner:alias>a4</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s71">
<annotation>
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</annotation>
</speciesReference>
</listOfProducts>
</reaction>
<reaction id="r39" reversible="false">
<annotation>
<celldesigner:reactionType>TRUNCATION</celldesigner:reactionType>
<celldesigner:baseReactants>s71</celldesigner:baseReactants>
<celldesigner:baseProducts>s90,s74</celldesigner:baseProducts>
<celldesigner:offset x="3.0" y="0.0"/>
<celldesigner:editPoints>0.3333333333333339,0.0 0.666666666666667,1.7763568394002505E-15 0.3333333333333339,-8.881784197001252E-16 0.6666666666666679,0.0 0.3333333333333339,-4.440892098500626E-16 0.6666666666666661,4.440892098500626E-16 0.30190189197491457,0.3296855800034484</celldesigner:editPoints>
</annotation>
<listOfReactants>
<speciesReference species="s71">
<annotation>
<celldesigner:alias>a79</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s90">
<annotation>
<celldesigner:alias>a80</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s74">
<annotation>
<celldesigner:alias>a81</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
</reaction>
<reaction id="r40" reversible="false">
<annotation>
<celldesigner:reactionType>KNOWN_TRANSITION_OMITTED</celldesigner:reactionType>
<celldesigner:baseReactants>s74</celldesigner:baseReactants>
<celldesigner:baseProducts>s75</celldesigner:baseProducts>
<celldesigner:editPoints>0.3333333333333339,-8.881784197001252E-16 0.6666666666666679,-8.881784197001252E-16</celldesigner:editPoints>
</annotation>
<listOfReactants>
<speciesReference species="s74">
<annotation>
<celldesigner:alias>a81</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s75">
<annotation>
<celldesigner:alias>a82</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
</reaction>
<reaction id="r41" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s77</celldesigner:baseReactants>
<celldesigner:baseProducts>s78</celldesigner:baseProducts>
<celldesigner:editPoints>0.33333333333333326,0.0 0.6666666666666667,0.0</celldesigner:editPoints>
<celldesigner:listOfModification>
<celldesigner:modification aliases="a88" editPoints="0.33333333333333326,0.0 0.6666666666666665,1.3322676295501878E-15" modifiers="s83" targetLineIndex="-1,1" type="CATALYSIS"/>
</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s77">
<annotation>
<celldesigner:alias>a83</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s78">
<annotation>
<celldesigner:alias>a84</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s83">
<annotation>
<celldesigner:alias>a88</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r44" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s78</celldesigner:baseReactants>
<celldesigner:baseProducts>s79</celldesigner:baseProducts>
<celldesigner:editPoints>0.3333333333333335,0.0 0.666666666666667,0.0</celldesigner:editPoints>
<celldesigner:listOfModification>
<celldesigner:modification aliases="a89" editPoints="0.33333333333333337,0.0 0.6666666666666669,0.0" modifiers="s85" targetLineIndex="-1,1" type="CATALYSIS"/>
</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s78">
<annotation>
<celldesigner:alias>a84</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s79">
<annotation>
<celldesigner:alias>a85</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s85">
<annotation>
<celldesigner:alias>a89</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r55" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s79</celldesigner:baseReactants>
<celldesigner:baseProducts>s81</celldesigner:baseProducts>
<celldesigner:editPoints>0.3333333333333339,0.0 0.6666666666666661,-1.7763568394002505E-15</celldesigner:editPoints>
<celldesigner:listOfModification>
<celldesigner:modification aliases="a108" editPoints="0.33333333333333304,4.440892098500626E-16 0.666666666666667,8.881784197001252E-16" modifiers="s120" targetLineIndex="-1,1" type="CATALYSIS"/>
</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s79">
<annotation>
<celldesigner:alias>a85</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s81">
<annotation>
<celldesigner:alias>a87</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s120">
<annotation>
<celldesigner:alias>a108</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r56" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s6</celldesigner:baseReactants>
<celldesigner:baseProducts>s77</celldesigner:baseProducts>
<celldesigner:editPoints>0.33333333333333326,-6.661338147750939E-16 0.6666666666666665,-1.3322676295501878E-15</celldesigner:editPoints>
<celldesigner:listOfModification>
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</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s6">
<annotation>
<celldesigner:alias>a4</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s77">
<annotation>
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</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s117">
<annotation>
<celldesigner:alias>a107</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r57" reversible="false">
<annotation>
<celldesigner:reactionType>KNOWN_TRANSITION_OMITTED</celldesigner:reactionType>
<celldesigner:baseReactants>s81</celldesigner:baseReactants>
<celldesigner:baseProducts>s82</celldesigner:baseProducts>
<celldesigner:editPoints>0.3333333333333339,0.0 0.6666666666666661,0.0</celldesigner:editPoints>
</annotation>
<listOfReactants>
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<annotation>
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</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s82">
<annotation>
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</annotation>
</speciesReference>
</listOfProducts>
</reaction>
<reaction id="r58" reversible="false">
<annotation>
<celldesigner:reactionType>KNOWN_TRANSITION_OMITTED</celldesigner:reactionType>
<celldesigner:baseReactants>s82</celldesigner:baseReactants>
<celldesigner:baseProducts>s122</celldesigner:baseProducts>
<celldesigner:editPoints>0.3333333333333339,0.0 0.666666666666667,0.0</celldesigner:editPoints>
</annotation>
<listOfReactants>
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<annotation>
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</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s122">
<annotation>
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</annotation>
</speciesReference>
</listOfProducts>
</reaction>
<reaction id="r59" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s79</celldesigner:baseReactants>
<celldesigner:baseProducts>s79</celldesigner:baseProducts>
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<celldesigner:listOfModification>
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<annotation>
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</speciesReference>
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<listOfProducts>
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</speciesReference>
</listOfProducts>
<listOfModifiers>
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<annotation>
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</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r61" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s79</celldesigner:baseReactants>
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<celldesigner:listOfReactantLinks>
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</celldesigner:listOfReactantLinks>
<celldesigner:listOfProductLinks>
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</celldesigner:listOfProductLinks>
<celldesigner:editPoints>0.33333333333333304,0.0 0.6666666666666661,1.7763568394002505E-15</celldesigner:editPoints>
<celldesigner:listOfModification>
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</annotation>
<listOfReactants>
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<annotation>
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</speciesReference>
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<annotation>
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</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
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<annotation>
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</annotation>
</speciesReference>
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<annotation>
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</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
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<annotation>
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</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
</listOfReactions>
</model>
</sbml>


