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The blood coagulation cascade and fibrinolytic pathway.
Medline=10856975
Medline=12871284
free text=Loscalzo J., Schafer A.I. (ed). Thrombosis and Hemorrhage (Third Edition). Lippincott  Williams & Wilkins (2003).
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<celldesigner:protein id="p69" name="ZPI" type="GENERIC"/>
<celldesigner:protein id="p70" name="PZ" type="GENERIC"/>
<celldesigner:protein id="p80" name="uPAR" type="RECEPTOR"/>
<celldesigner:protein id="p81" name="uPA" type="GENERIC"/>
<celldesigner:protein id="p84" name="mPAR-3" type="RECEPTOR"/>
<celldesigner:protein id="p86" name="GP IIIa" type="RECEPTOR"/>
<celldesigner:protein id="p87" name="GP IIb" type="RECEPTOR"/>
<celldesigner:protein id="p88" name="GP 1b_beta_" type="RECEPTOR"/>
<celldesigner:protein id="p89" name="GP IX" type="RECEPTOR"/>
<celldesigner:protein id="p90" name="GP Ib_alpha_" type="RECEPTOR"/>
<celldesigner:protein id="p91" name="GP V" type="RECEPTOR"/>
<celldesigner:protein id="p92" name="EPCR" type="RECEPTOR"/>
<celldesigner:protein id="p93" name="Kininogen" type="TRUNCATED"/>
<celldesigner:protein id="p94" name="Bradykinin" type="TRUNCATED"/>
<celldesigner:protein id="p44" name="TFPI" type="GENERIC"/>
<celldesigner:protein id="p35" name="Fibrin polymer_br_cross-linked" type="GENERIC"/>
<celldesigner:protein id="p95" name="?" type="TRUNCATED"/>
</celldesigner:listOfProteins>
<celldesigner:listOfBlockDiagrams/>
</annotation>
<listOfCompartments>
<compartment name="default" volume="1.0"/>
<compartment name="c1" outside="default" volume="1.0">
<annotation>
<celldesigner:name>activated platelet</celldesigner:name>
</annotation>
</compartment>
</listOfCompartments>
<listOfSpecies>
<species compartment="default" initialAmount="0.0" name="s3">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  calcium
Synonym:  Synonym not specified
Accession:  U02177
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>ION</celldesigner:class>
<celldesigner:name>Ca_super_2_plus_</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s6">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Factor Xa
Synonym:  Stuart-Prower Factor
Accession:  P00445
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p5</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r87"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s4">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Factor V
Synonym:  FV,Proaccelerin,accelerator (Ac-) globulin,labile factor
Accession:  P00432
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p3</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s5">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Factor X
Synonym:  Stuart-Prower Factor
Accession:  P00430
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p4</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s19">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Factor IX
Synonym:  Christmas Factor,antihemophilic factor B,plasma thromboplastin component (PTC
Accession:  P00444
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p11</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s20">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Factor IXa
Synonym:  Christmas Factor,FIXa,antihemophilic factor B,plasma thromboplastin component, PTC
Accession:  P00422
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p12</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s25">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Fibrinogen
Synonym:  Factor I
Accession:  P00406
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p15</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s28">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  FXIa
Synonym:  plasma thromboplastin antecedent
Accession:  P00434
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p18</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r157"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s29">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Factor XIIa
Synonym:  Hageman Factor
Accession:  P00441
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p19</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r152"/>
<celldesigner:catalyzed reaction="r154"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s30">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Factor XII
Synonym:  Hageman Factor
Accession:  P00442
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p20</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s31">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  anionic phospholipids
Synonym:  Synonym not specified
Accession:  S01611
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>PL</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s36">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  negative charged surface
Synonym:  Synonym not specified
Accession:  S01613
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>negative charged surface</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s35">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Prekallikrein
Synonym:  Fletcher factor
Accession:  P00439
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p24</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s37">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  High molecular weight kininogen
Synonym:  Fitzgerald, Flaujeac Williams factor,HMWK,contact activation cofactor,plasma thromboplastin antecedent
Accession:  P00413
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p22</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s38">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  kallikrein
Synonym:  Fletcher factor
Accession:  P00437
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p25</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r87"/>
<celldesigner:catalyzed reaction="r90"/>
<celldesigner:catalyzed reaction="r153"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s1">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Prothrombin
Synonym:  Factor II
Accession:  P00416
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p28</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s2">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Thrombin
Synonym:  Factor IIa
Accession:  P00414
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p29</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r129"/>
<celldesigner:catalyzed reaction="r147"/>
<celldesigner:catalyzed reaction="r148"/>
<celldesigner:catalyzed reaction="r149"/>
<celldesigner:catalyzed reaction="r156"/>
<celldesigner:catalyzed reaction="r160"/>
<celldesigner:catalyzed reaction="r162"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s26">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Fibrin monomer
Synonym:  Synonym not specified
Accession:  P00418
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p30</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s42">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Factor XIII
Synonym:  FXIII,Protransglutaminase,fibrin stabilizing factor, FSF,fibrinoligase
Accession:  P00453
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p32</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s43">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Factor XIIIa
Synonym:  FXIIIa,Protransglutaminase,fibrin stabilizing factor, FSF,fibrinoligase
Accession:  P00419
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p33</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r163"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s47">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Protein C
Synonym:  FXIV,PC,anticoagulant protein C,autoprothrombin IIA,vitamin K-dependent protein C
Accession:  P00426
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p39</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s52">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  Protein S
Synonym:  Synonym not specified
Accession:  U05119
Heterodimer Member Info:  PS#PROTEIN#Protein S#P00412#PS#;APC#PROTEIN#Activated Protein C#P00423#FXIV|anticoagulant protein C|autoprothrombin IIA|vitamin K-dependent protein C#
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p43</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p40</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r165"/>
<celldesigner:catalyzed reaction="r166"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s56">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Fibrin degradation
Synonym:  Synonym not specified
Accession:  U02179
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>DEGRADED</celldesigner:class>
<celldesigner:name>a52_degraded</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s57">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Plasminogen
Synonym:  Synonym not specified
Accession:  P00408
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p46</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s62">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Plasmin
Synonym:  Synonym not specified
Accession:  P00415
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p50</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r41"/>
<celldesigner:catalyzed reaction="r87"/>
<celldesigner:catalyzed reaction="r90"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s63">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Tissue plasminogen activator
Synonym:  tPA
Accession:  P00431
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p51</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r164"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s65">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  plasminogen activator inhibitor type-1
Synonym:  PAI-1,endothelial plasminogen activator inhibitor,serine (or cysteine) protease inhibitor, clade E, member 1
Accession:  P00411
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p53</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s66">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  alpha2-antiplasmin
Synonym:  Alpha-2-AP,Alpha-2-PI,plasmin inhibitor alpha2,serine (or cysteine) protease inhibitor, clade F, member 2
Accession:  P00428
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p55</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s67">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  alpha-2-macroglobulin
Synonym:  alpha2M
Accession:  P00427
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p56</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s68">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  plasminogen activator-inhibitors type 2
Synonym:  PAI-2,serine (or cysteine) protease inhibitor, clade B, member 2
Accession:  P00409
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p57</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s69">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Antithrombin III
Synonym:  ATIII
Accession:  P00440
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p58</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s70">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  heparan
Synonym:  Synonym not specified
Accession:  S01612
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Heparan</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s71">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  heparin cofactor II
Synonym:  HCII
Accession:  P00456
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p59</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s72">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  alpha1-antitrypsin
Synonym:  AAT,APS,alpha-1-antiproteinase,alpha-1-protease inhibitor,alpha1-AT
Accession:  P00421
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p62</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="c1" initialAmount="0.0" name="s74">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Protease-activated receptor1
Synonym:  PAR-1,coagulation factor II receptor,thrombin receptor
Accession:  P00404
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p64</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="c1" initialAmount="0.0" name="s76">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Protease-activated receptor4
Synonym:  PAR-4,coagulation factor II receptor-like 3,thrombin receptor-like 3
Accession:  P00461
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p66</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s77">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  Factor XI
Synonym:  Synonym not specified
Accession:  U05124
Heterodimer Member Info:  HMWK#PROTEIN#High molecular weight kininogen#P00413#Fitzgerald, Flaujeac Williams factor|HMWK|contact activation cofactor|plasma thromboplastin antecedent#;FXI#PROTEIN#Factor XI#P00460#plasma thromboplastin antecedent#
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p22</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p17</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s78">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Zn2+
Synonym:  Synonym not specified
Accession:  U02178
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>ION</celldesigner:class>
<celldesigner:name>Zn_super_2_plus_</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s79">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Protease nexin II
Synonym:  A4,AAA,AD1,Alzheimer's disease amyloid A4 protein precursor ,CVAP,PN2,amyloid beta (A4) precursor protein (APP)
Accession:  P00429
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p67</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s80">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  protein Z-dependent protease inhibitor
Synonym:  ZPI
Accession:  P00425
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p69</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s100">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  urokinase plasminogen activator
Synonym:  uPA
Accession:  P00424
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p81</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r164"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s101">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  urokinase plasminogen activator
Synonym:  Synonym not specified
Accession:  U05113
Heterodimer Member Info:  uPA#PROTEIN#urokinase plasminogen activator#P00424#uPA#;uPAR#PROTEIN#urokinase-type plasminogen activator receptor#P00433#CD87|uPAR#
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p81</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p80</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
</annotation>
</species>
<species compartment="c1" initialAmount="0.0" name="s103">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  mouse Protease-activated receptor 3
Synonym:  mPAR-3
Accession:  P00452
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p84</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="c1" initialAmount="0.0" name="s115">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  glycoprotein 1b-beta
Synonym:  Synonym not specified
Accession:  U05114
Heterodimer Member Info:  GP 1bbeta#PROTEIN#Glycoprotein 1bbeta#P00436#GP Ibbeta|GPIb#;GP Ibalpha#PROTEIN#Glycoprotein Ibalpha#P00449#GP 1balpha|GPIb#
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p88</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p90</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
</annotation>
</species>
<species compartment="c1" initialAmount="0.0" name="s116">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  glycoprotein IX
Synonym:  Synonym not specified
Accession:  U05110
Heterodimer Member Info:  GP V#PROTEIN#Glycoprotein V#P00420##;GP IX#PROTEIN#Glycoprotein IX#P00455#CD42a|GP IX|GP9#
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p91</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p89</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s120">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  Protein C
Synonym:  Synonym not specified
Accession:  U05120
Heterodimer Member Info:  EPCR#PROTEIN#Endothelial cell protein C receptor #P00403#EPCR#;PC#PROTEIN#Protein C#P00426#FXIV|PC|anticoagulant protein C|autoprothrombin IIA|vitamin K-dependent protein C#
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p39</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p92</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s121">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  Long name not specified
Synonym:  Synonym not specified
Accession:  U05129
Heterodimer Member Info:  HMWK#PROTEIN#High molecular weight kininogen#P00413#Fitzgerald, Flaujeac Williams factor|HMWK|contact activation cofactor|plasma thromboplastin antecedent#;Kallikrein#PROTEIN#kallikrein#P00437#Fletcher factor#
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p25</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p22</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r168"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s122">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Kininogen
Synonym:  Alpha-2-thiol proteinase inhibitor,KNG
Accession:  P00451
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p93</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s123">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Bradykinin
Synonym:  Synonym not specified
Accession:  P00438
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p94</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="c1" initialAmount="0.0" name="s126">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  Long name not specified
Synonym:  Synonym not specified
Accession:  U05130
Heterodimer Member Info:  GP IIb#PROTEIN#Glycoprotein IIb#P00410#CD41|GPalphaIIb|integrin alpha-2B#;GP IIIa#PROTEIN#Glycoprotein IIIa#P00458#CD61|GP3A|GPIIIa|beta 3 integrin#
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p87</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p86</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
</annotation>
</species>
<species compartment="c1" initialAmount="0.0" name="s131">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  Long name not specified
Synonym:  Synonym not specified
Accession:  U05127
Heterodimer Member Info:  Fibrinogen#PROTEIN#Fibrinogen#P00406#Factor I#;GP IIb#PROTEIN#Glycoprotein IIb#P00410#CD41|GPalphaIIb|integrin alpha-2B#;GP IIIa#PROTEIN#Glycoprotein IIIa#P00458#CD61|GP3A|GPIIIa|beta 3 integrin#
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p86</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p87</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner2" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p15</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
</annotation>
</species>
<species compartment="c1" initialAmount="0.0" name="s132">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  activated platelet response
Synonym:  Synonym not specified
Accession:  U02180
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PHENOTYPE</celldesigner:class>
<celldesigner:name>activated platelet_br_response</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s137">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  Long name not specified
Synonym:  Synonym not specified
Accession:  U05111
Heterodimer Member Info:  PL#SIMPLE_MOLECULE#anionic phospholipids#S01611##;Ca2+#ION#calcium#U02177##;Thrombomodulin#PROTEIN#Thrombomodulin#P00457#CD141|TM|fetomodulin#
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p36</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>ION</celldesigner:class>
<celldesigner:name>Ca_super_2_plus_</celldesigner:name>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner2" originalSpecies="unknown">
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>PL</celldesigner:name>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s140">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  Long name not specified
Synonym:  Synonym not specified
Accession:  U05126
Heterodimer Member Info:  Thrombin#PROTEIN#Thrombin#P00414#Factor IIa#;PL#SIMPLE_MOLECULE#anionic phospholipids#S01611##;Ca2+#ION#calcium#U02177##;Thrombomodulin#PROTEIN#Thrombomodulin#P00457#CD141|TM|fetomodulin#
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p36</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p29</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner2" originalSpecies="unknown">
<celldesigner:class>ION</celldesigner:class>
<celldesigner:name>Ca_super_2_plus_</celldesigner:name>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner3" originalSpecies="unknown">
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>PL</celldesigner:name>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r132"/>
<celldesigner:catalyzed reaction="r133"/>
<celldesigner:catalyzed reaction="r155"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s141">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  Long name not specified
Synonym:  Synonym not specified
Accession:  U05109
Heterodimer Member Info:  FVIII#PROTEIN#Factor VIII#P00405##;vWF#PROTEIN#von Willebrand Factor#P00448##
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p49</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p48</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s61">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  von Willebrand Factor
Synonym:  Synonym not specified
Accession:  P00448
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p49</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s142">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  FVIIIa
Synonym:  Synonym not specified
Accession:  P00446
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p13</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s15">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  FVII
Synonym:  Proconvertin,cothromboplastin,serum prothrombin conversion accelerator (SPCA)
Accession:  P00454
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p9</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s145">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  Long name not specified
Synonym:  Synonym not specified
Accession:  U05123
Heterodimer Member Info:  PL#SIMPLE_MOLECULE#anionic phospholipids#S01611##;Ca2+#ION#calcium#U02177##;Tissue Factor#PROTEIN#Tissue Factor#P00450#CD142|Factor III|thromboplastin#
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p26</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>PL</celldesigner:name>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner2" originalSpecies="unknown">
<celldesigner:class>ION</celldesigner:class>
<celldesigner:name>Ca_super_2_plus_</celldesigner:name>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s148">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  Long name not specified
Synonym:  Synonym not specified
Accession:  U05122
Heterodimer Member Info:  PL#SIMPLE_MOLECULE#anionic phospholipids#S01611##;Ca2+#ION#calcium#U02177##;FVIIa#PROTEIN#Factor VIIa#P00447#Proconvertin|cothromboplastin|serum prothrombin conversion accelerator (SPCA)#;Tissue Factor#PROTEIN#Tissue Factor#P00450#CD142|Factor III|thromboplastin#
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p27</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p26</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner2" originalSpecies="unknown">
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>PL</celldesigner:name>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner3" originalSpecies="unknown">
<celldesigner:class>ION</celldesigner:class>
<celldesigner:name>Ca_super_2_plus_</celldesigner:name>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r157"/>
<celldesigner:catalyzed reaction="r159"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s53">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Tissue Factor Pathway Inhibitor
Synonym:  TFPI,anticonvertin,extrinsic pathway inhibitor (EPI),lipoprotein-associated coagulation inhibitor (LACI)
Accession:  P00417
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p44</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s154">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  Long name not specified
Synonym:  Synonym not specified
Accession:  U05121
Heterodimer Member Info:  PL#SIMPLE_MOLECULE#anionic phospholipids#S01611##;Ca2+#ION#calcium#U02177##;FXa#PROTEIN#Factor Xa#P00445#Stuart-Prower Factor#;FVIIa#PROTEIN#Factor VIIa#P00447#Proconvertin|cothromboplastin|serum prothrombin conversion accelerator (SPCA)#;Tissue Factor#PROTEIN#Tissue Factor#P00450#CD142|Factor III|thromboplastin#
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p26</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p27</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner2" originalSpecies="unknown">
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>PL</celldesigner:name>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner3" originalSpecies="unknown">
<celldesigner:class>ION</celldesigner:class>
<celldesigner:name>Ca_super_2_plus_</celldesigner:name>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner4" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p5</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s159">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  Long name not specified
Synonym:  Synonym not specified
Accession:  U05116
Heterodimer Member Info:  TFPI#PROTEIN#Tissue Factor Pathway Inhibitor#P00417#TFPI|anticonvertin|extrinsic pathway inhibitor (EPI)|lipoprotein-associated coagulation inhibitor (LACI)#;PL#SIMPLE_MOLECULE#anionic phospholipids#S01611##;Ca2+#ION#calcium#U02177##;FXa#PROTEIN#Factor Xa#P00445#Stuart-Prower Factor#;FVIIa#PROTEIN#Factor VIIa#P00447#Proconvertin|cothromboplastin|serum prothrombin conversion accelerator (SPCA)#;Tissue Factor#PROTEIN#Tissue Factor#P00450#CD142|Factor III|thromboplastin#
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p44</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p26</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner2" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p27</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner3" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p5</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner4" originalSpecies="unknown">
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>PL</celldesigner:name>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner5" originalSpecies="unknown">
<celldesigner:class>ION</celldesigner:class>
<celldesigner:name>Ca_super_2_plus_</celldesigner:name>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s41">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Fibrin polymer cross-linked
Synonym:  Synonym not specified
Accession:  P00443
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p35</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s163">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  Long name not specified
Synonym:  Synonym not specified
Accession:  U05117
Heterodimer Member Info:  PL#SIMPLE_MOLECULE#anionic phospholipids#S01611##;FVa#PROTEIN#Factor Va#P00435#FVa|accelerator (Ac-) globulin|labile factor|proaccelerin#;Ca2+#ION#calcium#U02177##;FXa#PROTEIN#Factor Xa#P00445#Stuart-Prower Factor#
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p5</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p6</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner2" originalSpecies="unknown">
<celldesigner:class>ION</celldesigner:class>
<celldesigner:name>Ca_super_2_plus_</celldesigner:name>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner3" originalSpecies="unknown">
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>PL</celldesigner:name>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r167"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s164">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Protein S
Synonym:  PS
Accession:  P00412
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p43</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s165">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Activated Protein C
Synonym:  FXIV,anticoagulant protein C,autoprothrombin IIA,vitamin K-dependent protein C
Accession:  P00423
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p40</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s166">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Endothelial cell protein C receptor
Synonym:  EPCR
Accession:  P00403
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p92</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s177">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  Long name not specified
Synonym:  Synonym not specified
Accession:  U05115
Heterodimer Member Info:  PZ#PROTEIN#Protein Z#P00407##;ZPI#PROTEIN#protein Z-dependent protease inhibitor#P00425#ZPI#
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p69</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p70</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s180">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  Long name not specified
Synonym:  Synonym not specified
Accession:  U05118
Heterodimer Member Info:  PZ#PROTEIN#Protein Z#P00407##;ZPI#PROTEIN#protein Z-dependent protease inhibitor#P00425#ZPI#;PL#SIMPLE_MOLECULE#anionic phospholipids#S01611##;Ca2+#ION#calcium#U02177##;FXa#PROTEIN#Factor Xa#P00445#Stuart-Prower Factor#
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p69</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p70</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner2" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p5</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner3" originalSpecies="unknown">
<celldesigner:class>ION</celldesigner:class>
<celldesigner:name>Ca_super_2_plus_</celldesigner:name>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner4" originalSpecies="unknown">
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>PL</celldesigner:name>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s181">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  urokinase-type plasminogen activator receptor
Synonym:  CD87,uPAR
Accession:  P00433
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p80</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" initialAmount="0.0" name="s184">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  Long name not specified
Synonym:  Synonym not specified
Accession:  U05125
Heterodimer Member Info:  FIXa#PROTEIN#Factor IXa#P00422#Christmas Factor|FIXa|antihemophilic factor B|plasma thromboplastin component, PTC#;PL#SIMPLE_MOLECULE#anionic phospholipids#S01611##;Ca2+#ION#calcium#U02177##;FVIIIa#PROTEIN#FVIIIa#P00446##
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p12</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>ION</celldesigner:class>
<celldesigner:name>Ca_super_2_plus_</celldesigner:name>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner2" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p13</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner3" originalSpecies="unknown">
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>PL</celldesigner:name>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r159"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="c1" initialAmount="0.0" name="s193">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  Long name not specified
Synonym:  Synonym not specified
Accession:  U05112
Heterodimer Member Info:  GP V#PROTEIN#Glycoprotein V#P00420##;GP 1bbeta#PROTEIN#Glycoprotein 1bbeta#P00436#GP Ibbeta|GPIb#;GP Ibalpha#PROTEIN#Glycoprotein Ibalpha#P00449#GP 1balpha|GPIb#;GP IX#PROTEIN#Glycoprotein IX#P00455#CD42a|GP IX|GP9#
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p89</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner1" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p88</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner2" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p90</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
<celldesigner:heterodimerEntry innerId="inner3" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p91</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
</celldesigner:listOfHeterodimerEntries>
</celldesigner:heterodimerIdentity>
</annotation>
</species>
<species compartment="c1" initialAmount="0.0" name="s198">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Long Name:  Long name not specified
Synonym:  Synonym not specified
Accession:  U05128
Heterodimer Member Info:  GP V#PROTEIN#Glycoprotein V#P00420##;GP 1bbeta#PROTEIN#Glycoprotein 1bbeta#P00436#GP Ibbeta|GPIb#;vWF#PROTEIN#von Willebrand Factor#P00448##;GP Ibalpha#PROTEIN#Glycoprotein Ibalpha#P00449#GP 1balpha|GPIb#;GP IX#PROTEIN#Glycoprotein IX#P00455#CD42a|GP IX|GP9#
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>transmembrane</celldesigner:positionToCompartment>
<celldesigner:heterodimerIdentity>
<celldesigner:listOfHeterodimerEntries>
<celldesigner:heterodimerEntry innerId="inner0" originalSpecies="unknown">
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p89</celldesigner:proteinReference>
</celldesigner:heterodimerEntry>
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Long Name:  ?
Synonym:  Synonym not specified
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Long Name:  Factor Va
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</annotation>
</speciesReference>
</listOfProducts>
</reaction>
<reaction name="r168" reversible="false">
<annotation>
<celldesigner:reactionType>TRUNCATION</celldesigner:reactionType>
<celldesigner:baseReactants>s121</celldesigner:baseReactants>
<celldesigner:baseProducts>s122,s123</celldesigner:baseProducts>
<celldesigner:listOfProductLinks>
<celldesigner:productLink alias="a180" product="s38" targetLineIndex="0,1"/>
</celldesigner:listOfProductLinks>
<celldesigner:editPoints>0.3333333333333335,-4.440892098500626E-16 0.6666666666666665,-4.440892098500626E-16 0.33333333333333337,0.0 0.6666666666666669,8.881784197001252E-16 0.33333333333333304,2.220446049250313E-16 0.6666666666666661,2.220446049250313E-16 0.33333333333333326,0.33333333333333304</celldesigner:editPoints>
<celldesigner:listOfModification>
<celldesigner:modification aliases="a179" editPoints="-1.9694480854329184,-2.055641080333336 1.5945816257272165,-2.2683992628162866" modifiers="s121" offsetX="7.0" offsetY="-37.0" targetLineIndex="0,0" type="CATALYSIS"/>
</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s121">
<annotation>
<celldesigner:alias>a179</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s122">
<annotation>
<celldesigner:alias>a183</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s123">
<annotation>
<celldesigner:alias>a185</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s38">
<annotation>
<celldesigner:alias>a180</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
</reaction>
</listOfReactions>
</model>
</sbml>

