<?xml version="1.0" encoding="UTF-8"?>
<!-- Terms and Conditions -->
<!-- 
Copyright (C)) 2005 Applied Biosystems.  
This file may be copied and redistributed freely, without advance permission, 
provided that this Copyright statement is reproduced with each copy.  
 
LIMITATION OF WARRANTY 
NOTHING IN THIS AGREEMENT WILL BE CONSTRUED AS A REPRESENTATION MADE OR 
WARRANTY GIVEN BY APPLIED BIOSYSTEMS OR ANY THIRD PARTY THAT THE USE OF 
DATA PROVIDED HEREUNDER WILL NOT INFRINGE ANY PATENT, COPYRIGHT, TRADEMARK 
OR OTHER RIGHTS OF ANY THIRD PARTY. DATA IS PROVIDED "AS IS" WITHOUT 
WARRANTY OF ANY KIND WHATSOEVER, EXPRESS OR IMPLIED, INCLUDING IMPLIED 
WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. APPLIED 
BIOSYSTEMS MAKES NO WARRANTY THAT ITS DATA DOES NOT CONTAIN ERRORS.
-->

<!-- Created by SBML API 2.0(a17.0) -->
<sbml level="2" version="1" xmlns="http://www.sbml.org/sbml/level2" xmlns:celldesigner="http://www.sbml.org/2001/ns/celldesigner">
<model id="Purine_space_metabolism">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
<![CDATA[
The pattern of breakdown is very different for the two types of nucletide bases, purines and pyrimidines.  In the case of pyrimidines the ring is reduced and then opened, and with the exception 
of beta-alanine the nitrogen is removed by deamination and transamination as ammonia, which must ultimately be converted into urea.  However, in the case of purines only the amino nitrogen outside the ring is removed as ammonia.  The purine ring itself is oxidized to uric acid by xanthine oxidase and excreted.  In humans and primates, the conversion of urate to allantoin occurs non-enzymatically by interaction with oxygen free radicals.
free text=Biochemiscal Pathways - An Atlas of Biochemistry and Molecular Biology Edited by Gerhard Michal
free text=Color Atlas of Biochemistry by Jan Koolman and Klaus-Heinrich Rohm
free text=Human Metabolism by Ramsey Bronk
]]>
</body>
</html>
</notes>
<annotation>
<celldesigner:modelVersion>2.3</celldesigner:modelVersion>
<celldesigner:modelDisplay sizeX="900" sizeY="600"/>
<celldesigner:listOfCompartmentAliases/>
<celldesigner:listOfSpeciesAliases>
<celldesigner:speciesAlias id="a3" species="s3">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="33.0" w="118.0" x="124.5" y="64.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a157" species="s168">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="33.0" w="118.0" x="125.0" y="271.5"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a158" species="s171">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="33.0" w="118.0" x="667.0" y="29.5"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a159" species="s170">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="35.0" w="126.0" x="299.0" y="163.5"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a160" species="s169">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="33.0" w="118.0" x="125.0" y="483.5"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a161" species="s174">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="33.0" w="118.0" x="501.0" y="397.5"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a162" species="s173">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="33.0" w="118.0" x="503.0" y="269.5"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a163" species="s172">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="33.0" w="118.0" x="501.0" y="129.5"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a164" species="s175">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="33.0" w="118.0" x="749.0" y="397.5"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a165" species="s176">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="33.0" w="118.0" x="749.0" y="537.5"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a166" species="s177">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="28.0" w="76.0" x="264.0" y="58.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a167" species="s179">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="26.0" w="64.0" x="329.0" y="108.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a168" species="s180">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="24.0" w="54.0" x="316.0" y="232.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a169" species="s181">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="28.0" w="112.0" x="96.0" y="153.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ff66ccff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a170" species="s182">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="28.0" w="112.0" x="96.0" y="196.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ff66ccff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a171" species="s183">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="24.0" w="54.0" x="261.0" y="280.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a172" species="s183">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="24.0" w="54.0" x="109.0" y="326.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a173" species="s184">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="33.0" w="118.0" x="235.0" y="423.5"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a174" species="s185">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="25.0" w="152.0" x="10.0" y="436.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ff66ccff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a175" species="s186">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="28.0" w="72.0" x="267.0" y="506.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a176" species="s189">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="32.0" w="78.0" x="445.0" y="468.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a177" species="s190">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="28.0" w="98.0" x="353.0" y="511.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ff66ccff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a178" species="s180">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="24.0" w="54.0" x="601.0" y="36.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a179" species="s183">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="24.0" w="54.0" x="527.0" y="74.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a180" species="s182">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="28.0" w="112.0" x="708.0" y="108.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ff66ccff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a181" species="s183">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="24.0" w="54.0" x="473.0" y="164.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a182" species="s184">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="33.0" w="118.0" x="609.0" y="241.5"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a183" species="s185">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="27.0" w="152.0" x="643.0" y="177.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ff66ccff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a184" species="s177">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="28.0" w="76.0" x="466.0" y="310.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a185" species="s179">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="26.0" w="64.0" x="596.0" y="367.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a186" species="s191">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="28.0" w="120.0" x="642.0" y="307.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ff66ccff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a187" species="s186">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="28.0" w="72.0" x="586.0" y="432.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a188" species="s189">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="32.0" w="78.0" x="711.0" y="432.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a189" species="s190">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="28.0" w="98.0" x="635.0" y="468.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ff66ccff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a190" species="s192">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="28.0" w="56.0" x="834.0" y="438.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
<celldesigner:speciesAlias id="a191" species="s193">
<celldesigner:activity>inactive</celldesigner:activity>
<celldesigner:bounds h="24.0" w="54.0" x="833.0" y="504.0"/>
<celldesigner:singleLine width="1.0"/>
<celldesigner:paint color="ffffffff" scheme="Color"/>
</celldesigner:speciesAlias>
</celldesigner:listOfSpeciesAliases>
<celldesigner:listOfGroups/>
<celldesigner:listOfProteins>
<celldesigner:protein id="p60" name="5_super_'_endsuper_-AMP Deaminase" type="GENERIC"/>
<celldesigner:protein id="p61" name="5_super_'_endsuper_-Nucleotidase" type="GENERIC"/>
<celldesigner:protein id="p62" name="Nucleoside Phosphorylase" type="GENERIC"/>
<celldesigner:protein id="p63" name="Xanthine Oxidase" type="GENERIC"/>
<celldesigner:protein id="p64" name="Guanine Deaminase" type="GENERIC"/>
</celldesigner:listOfProteins>
<celldesigner:listOfBlockDiagrams/>
</annotation>
<listOfCompartments>
<compartment id="default" size="1.0"/>
</listOfCompartments>
<listOfSpecies>
<species compartment="default" id="s3" initialAmount="0.0" name="AMP">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  AMP
Synonym:  Synonym not specified
Accession:  S04054
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>AMP</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s168" initialAmount="0.0" name="Inosine">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Inosine
Synonym:  Synonym not specified
Accession:  S04055
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Inosine</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s169" initialAmount="0.0" name="Hypoxanthine">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Hypoxanthine
Synonym:  Synonym not specified
Accession:  S04040
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Hypoxanthine</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s171" initialAmount="0.0" name="GMP">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  GMP
Synonym:  Synonym not specified
Accession:  S04041
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>GMP</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s172" initialAmount="0.0" name="Guanosine">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Guanosine
Synonym:  Synonym not specified
Accession:  S04051
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Guanosine</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s173" initialAmount="0.0" name="Guanine">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Guanine
Synonym:  Synonym not specified
Accession:  S04039
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Guanine</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s174" initialAmount="0.0" name="Xanthine">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Xanthine
Synonym:  Synonym not specified
Accession:  S04038
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Xanthine</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s175" initialAmount="0.0" name="Urate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Urate
Synonym:  Synonym not specified
Accession:  S04049
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Urate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s176" initialAmount="0.0" name="Allantoin">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Allantoin
Synonym:  Synonym not specified
Accession:  S04047
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Allantoin</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s177" initialAmount="0.0" name="H_sub_2_endsub_O + H_super_+">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  H2O + H+
Synonym:  Synonym not specified
Accession:  S04043
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>H_sub_2_endsub_O + H_super_+</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s179" initialAmount="0.0" name="NH_sub_4_endsub_ _super_+">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  NH4 +
Synonym:  Synonym not specified
Accession:  S04052
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>NH_sub_4_endsub_ _super_+</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s180" initialAmount="0.0" name="H_sub_2_endsub_O">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  H2O
Synonym:  Synonym not specified
Accession:  S04042
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>H_sub_2_endsub_O</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s181" initialAmount="0.0" name="5_super_'_endsuper_-AMP Deaminase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  5'-AMP Deaminase
Synonym:  Synonym not specified
Accession:  P03117
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p60</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r80"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s182" initialAmount="0.0" name="5_super_'_endsuper_-Nucleotidase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  5'-Nucleotidase
Synonym:  Synonym not specified
Accession:  P03119
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p61</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r79"/>
<celldesigner:catalyzed reaction="r81"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s183" initialAmount="0.0" name="P_sub_i_endsub_">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Pi
Synonym:  Synonym not specified
Accession:  S04050
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>P_sub_i_endsub_</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s184" initialAmount="0.0" name="Ribose 1-Phosphate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Ribose 1-Phosphate
Synonym:  Synonym not specified
Accession:  S04048
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Ribose 1-Phosphate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s185" initialAmount="0.0" name="Nucleoside Phosphorylase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Nucleoside Phosphorylase
Synonym:  Synonym not specified
Accession:  P03115
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p62</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r78"/>
<celldesigner:catalyzed reaction="r82"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s186" initialAmount="0.0" name="H_sub_2_endsub_O + O_sub_2_endsub_">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  H2O + O2
Synonym:  Synonym not specified
Accession:  S04053
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>H_sub_2_endsub_O + O_sub_2_endsub_</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s189" initialAmount="0.0" name="2H_super_+_endsuper_ + O_sub_2_endsub_ _super_-._endsuper">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  2H+ + O2 -.
Synonym:  Synonym not specified
Accession:  S04045
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>2H_super_+_endsuper_ + O_sub_2_endsub_ _super_-._endsuper</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s190" initialAmount="0.0" name="Xanthine Oxidase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Xanthine Oxidase
Synonym:  Synonym not specified
Accession:  P03116
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p63</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r84"/>
<celldesigner:catalyzed reaction="r86"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s191" initialAmount="0.0" name="Guanine Deaminase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Guanine Deaminase
Synonym:  Synonym not specified
Accession:  P03118
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p64</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r83"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s192" initialAmount="0.0" name="O_sub_2_endsub_ _super_-._endsuper">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  O2 -.
Synonym:  Synonym not specified
Accession:  S04056
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>O_sub_2_endsub_ _super_-._endsuper</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s193" initialAmount="0.0" name="CO_sub_2_endsub">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  CO2
Synonym:  Synonym not specified
Accession:  S04046
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>CO_sub_2_endsub</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s170" initialAmount="0.0" name="Inosine-5_super_'_endsuper_-phosphate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Inosine-5'-phosphate
Synonym:  Synonym not specified
Accession:  S04044
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Inosine-5_super_'_endsuper_-phosphate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
</listOfSpecies>
<listOfReactions>
<reaction id="r78" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s168</celldesigner:baseReactants>
<celldesigner:baseProducts>s169</celldesigner:baseProducts>
<celldesigner:listOfReactantLinks>
<celldesigner:reactantLink alias="a172" reactant="s183" targetLineIndex="-1,1"/>
</celldesigner:listOfReactantLinks>
<celldesigner:listOfProductLinks>
<celldesigner:productLink alias="a173" product="s184" targetLineIndex="-1,1"/>
</celldesigner:listOfProductLinks>
<celldesigner:editPoints>0.3333333333333335,0.0 0.6666666666666667,0.0</celldesigner:editPoints>
<celldesigner:listOfModification>
<celldesigner:modification aliases="a174" editPoints="0.3333333333333328,8.881784197001252E-16 0.6666666666666663,0.0" modifiers="s185" targetLineIndex="-1,-1" type="CATALYSIS"/>
</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s168">
<annotation>
<celldesigner:alias>a157</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s183">
<annotation>
<celldesigner:alias>a172</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s169">
<annotation>
<celldesigner:alias>a160</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s184">
<annotation>
<celldesigner:alias>a173</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s185">
<annotation>
<celldesigner:alias>a174</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r79" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s170</celldesigner:baseReactants>
<celldesigner:baseProducts>s168</celldesigner:baseProducts>
<celldesigner:listOfReactantLinks>
<celldesigner:reactantLink alias="a168" reactant="s180" targetLineIndex="-1,1"/>
</celldesigner:listOfReactantLinks>
<celldesigner:listOfProductLinks>
<celldesigner:productLink alias="a171" product="s183" targetLineIndex="-1,-1"/>
</celldesigner:listOfProductLinks>
<celldesigner:editPoints>0.3333333333333337,2.220446049250313E-16 0.666666666666667,0.0</celldesigner:editPoints>
<celldesigner:listOfModification>
<celldesigner:modification aliases="a170" editPoints="0.33333333333333326,-4.440892098500626E-16 0.6666666666666665,-1.1102230246251565E-15" modifiers="s182" targetLineIndex="-1,0" type="CATALYSIS"/>
</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s170">
<annotation>
<celldesigner:alias>a159</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s180">
<annotation>
<celldesigner:alias>a168</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s168">
<annotation>
<celldesigner:alias>a157</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s183">
<annotation>
<celldesigner:alias>a171</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s182">
<annotation>
<celldesigner:alias>a170</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r80" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s3</celldesigner:baseReactants>
<celldesigner:baseProducts>s170</celldesigner:baseProducts>
<celldesigner:listOfReactantLinks>
<celldesigner:reactantLink alias="a166" reactant="s177" targetLineIndex="-1,1"/>
</celldesigner:listOfReactantLinks>
<celldesigner:listOfProductLinks>
<celldesigner:productLink alias="a167" product="s179" targetLineIndex="-1,1"/>
</celldesigner:listOfProductLinks>
<celldesigner:editPoints>0.3333333333333335,-8.326672684688674E-17 0.666666666666667,-1.3877787807814457E-16</celldesigner:editPoints>
<celldesigner:listOfModification>
<celldesigner:modification aliases="a169" editPoints="0.33333333333333326,-2.220446049250313E-16 0.6666666666666665,0.0" modifiers="s181" targetLineIndex="-1,1" type="CATALYSIS"/>
</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s3">
<annotation>
<celldesigner:alias>a3</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s177">
<annotation>
<celldesigner:alias>a166</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s170">
<annotation>
<celldesigner:alias>a159</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s179">
<annotation>
<celldesigner:alias>a167</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s181">
<annotation>
<celldesigner:alias>a169</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r81" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s171</celldesigner:baseReactants>
<celldesigner:baseProducts>s172</celldesigner:baseProducts>
<celldesigner:listOfReactantLinks>
<celldesigner:reactantLink alias="a178" reactant="s180" targetLineIndex="-1,1"/>
</celldesigner:listOfReactantLinks>
<celldesigner:listOfProductLinks>
<celldesigner:productLink alias="a179" product="s183" targetLineIndex="-1,1"/>
</celldesigner:listOfProductLinks>
<celldesigner:editPoints>0.33333333333333304,-4.440892098500626E-16 0.6666666666666661,-4.440892098500626E-16</celldesigner:editPoints>
<celldesigner:listOfModification>
<celldesigner:modification aliases="a180" editPoints="0.3333333333333339,-4.440892098500626E-16 0.6666666666666661,-2.220446049250313E-16" modifiers="s182" targetLineIndex="-1,1" type="CATALYSIS"/>
</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s171">
<annotation>
<celldesigner:alias>a158</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s180">
<annotation>
<celldesigner:alias>a178</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s172">
<annotation>
<celldesigner:alias>a163</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s183">
<annotation>
<celldesigner:alias>a179</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s182">
<annotation>
<celldesigner:alias>a180</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r82" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s172</celldesigner:baseReactants>
<celldesigner:baseProducts>s173</celldesigner:baseProducts>
<celldesigner:listOfReactantLinks>
<celldesigner:reactantLink alias="a181" reactant="s183" targetLineIndex="-1,1"/>
</celldesigner:listOfReactantLinks>
<celldesigner:listOfProductLinks>
<celldesigner:productLink alias="a182" product="s184" targetLineIndex="-1,1"/>
</celldesigner:listOfProductLinks>
<celldesigner:editPoints>0.3333333333333335,-8.881784197001252E-16 0.6666666666666667,-8.881784197001252E-16</celldesigner:editPoints>
<celldesigner:listOfModification>
<celldesigner:modification aliases="a183" editPoints="0.3333333333333339,0.0 0.6666666666666679,-4.440892098500626E-16" modifiers="s185" targetLineIndex="-1,1" type="CATALYSIS"/>
</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s172">
<annotation>
<celldesigner:alias>a163</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s183">
<annotation>
<celldesigner:alias>a181</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s173">
<annotation>
<celldesigner:alias>a162</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s184">
<annotation>
<celldesigner:alias>a182</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s185">
<annotation>
<celldesigner:alias>a183</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r83" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s173</celldesigner:baseReactants>
<celldesigner:baseProducts>s174</celldesigner:baseProducts>
<celldesigner:listOfReactantLinks>
<celldesigner:reactantLink alias="a184" reactant="s177" targetLineIndex="-1,1"/>
</celldesigner:listOfReactantLinks>
<celldesigner:listOfProductLinks>
<celldesigner:productLink alias="a185" product="s179" targetLineIndex="-1,1"/>
</celldesigner:listOfProductLinks>
<celldesigner:editPoints>0.3333333333333335,0.0 0.6666666666666665,-8.881784197001252E-16</celldesigner:editPoints>
<celldesigner:listOfModification>
<celldesigner:modification aliases="a186" editPoints="0.3333333333333339,0.0 0.666666666666667,-8.881784197001252E-16" modifiers="s191" targetLineIndex="-1,1" type="CATALYSIS"/>
</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s173">
<annotation>
<celldesigner:alias>a162</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s177">
<annotation>
<celldesigner:alias>a184</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s174">
<annotation>
<celldesigner:alias>a161</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s179">
<annotation>
<celldesigner:alias>a185</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s191">
<annotation>
<celldesigner:alias>a186</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r84" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s174</celldesigner:baseReactants>
<celldesigner:baseProducts>s175</celldesigner:baseProducts>
<celldesigner:listOfReactantLinks>
<celldesigner:reactantLink alias="a187" reactant="s186" targetLineIndex="-1,1"/>
</celldesigner:listOfReactantLinks>
<celldesigner:listOfProductLinks>
<celldesigner:productLink alias="a188" product="s189" targetLineIndex="-1,1"/>
</celldesigner:listOfProductLinks>
<celldesigner:editPoints>0.33333333333333304,-2.220446049250313E-16 0.6666666666666665,-2.220446049250313E-16</celldesigner:editPoints>
<celldesigner:listOfModification>
<celldesigner:modification aliases="a189" editPoints="0.3333333333333339,0.0 0.666666666666667,0.0" modifiers="s190" targetLineIndex="-1,1" type="CATALYSIS"/>
</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s174">
<annotation>
<celldesigner:alias>a161</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s186">
<annotation>
<celldesigner:alias>a187</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s175">
<annotation>
<celldesigner:alias>a164</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s189">
<annotation>
<celldesigner:alias>a188</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s190">
<annotation>
<celldesigner:alias>a189</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r85" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s175</celldesigner:baseReactants>
<celldesigner:baseProducts>s176</celldesigner:baseProducts>
<celldesigner:listOfReactantLinks>
<celldesigner:reactantLink alias="a190" reactant="s192" targetLineIndex="-1,1"/>
</celldesigner:listOfReactantLinks>
<celldesigner:listOfProductLinks>
<celldesigner:productLink alias="a191" product="s193" targetLineIndex="-1,1"/>
</celldesigner:listOfProductLinks>
<celldesigner:editPoints>0.3333333333333335,-8.881784197001252E-16 0.666666666666667,0.0</celldesigner:editPoints>
</annotation>
<listOfReactants>
<speciesReference species="s175">
<annotation>
<celldesigner:alias>a164</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s192">
<annotation>
<celldesigner:alias>a190</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s176">
<annotation>
<celldesigner:alias>a165</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s193">
<annotation>
<celldesigner:alias>a191</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
</reaction>
<reaction id="r86" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s169</celldesigner:baseReactants>
<celldesigner:baseProducts>s174</celldesigner:baseProducts>
<celldesigner:listOfReactantLinks>
<celldesigner:reactantLink alias="a175" reactant="s186" targetLineIndex="-1,1"/>
</celldesigner:listOfReactantLinks>
<celldesigner:listOfProductLinks>
<celldesigner:productLink alias="a176" product="s189" targetLineIndex="-1,1"/>
</celldesigner:listOfProductLinks>
<celldesigner:editPoints>0.3333333333333332,0.0 0.6666666666666665,0.0</celldesigner:editPoints>
<celldesigner:listOfModification>
<celldesigner:modification aliases="a177" editPoints="0.33333333333333215,0.0 0.6666666666666661,0.0" modifiers="s190" targetLineIndex="-1,1" type="CATALYSIS"/>
</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s169">
<annotation>
<celldesigner:alias>a160</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s186">
<annotation>
<celldesigner:alias>a175</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s174">
<annotation>
<celldesigner:alias>a161</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s189">
<annotation>
<celldesigner:alias>a176</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s190">
<annotation>
<celldesigner:alias>a177</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
</listOfReactions>
</model>
</sbml>

