2.3 SQUARE_CLOSEUP_NORTHEAST inactive inactive inactive active inactive inactive inactive active inactive active inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive Smooth Muscle (gastric secretory cells) Long Name: histamine Synonym: Synonym not specified Accession: S04811 inside SIMPLE_MOLECULE histamine Long Name: GDP Synonym: Synonym not specified Accession: S04814 inside SIMPLE_MOLECULE GDP Long Name: GTP Synonym: Synonym not specified Accession: S04810 inside SIMPLE_MOLECULE GTP Long Name: Long name not specified Synonym: Synonym not specified Accession: U05277 Heterodimer Member Info: GTP#SIMPLE_MOLECULE#GTP#S04810##;G-Protein#PROTEIN#G-Protein#P04490## inside SIMPLE_MOLECULE GTP PROTEIN p8 Long Name: cAMP Synonym: Synonym not specified Accession: S04808 inside SIMPLE_MOLECULE cAMP Long Name: ATP Synonym: Synonym not specified Accession: S04807 inside SIMPLE_MOLECULE ATP Long Name: Long name not specified Synonym: Synonym not specified Accession: U05275 Heterodimer Member Info: H2#PROTEIN#H2#P04489##;histamine#SIMPLE_MOLECULE#histamine#S04811## transmembrane SIMPLE_MOLECULE histamine PROTEIN p1 Long Name: AC Synonym: adenylate cyclase,adenylate cyclase 2,adenylate cyclase 7,adenylyl cyclase Accession: P04492 inside PROTEIN p2 Long Name: PKA Synonym: protein kinase A Accession: P04491 inside PROTEIN p15 Long Name: cimetidine (tagamet) Synonym: Synonym not specified Accession: S04806 inside SIMPLE_MOLECULE cimetidine (tagamet) Long Name: ranitidine (zantac) Synonym: Synonym not specified Accession: S04813 inside SIMPLE_MOLECULE ranitidine (zantac) Long Name: tiotidine Synonym: Synonym not specified Accession: S04809 inside SIMPLE_MOLECULE tiotidine Long Name: Arachiodonic acid (AA) Synonym: Synonym not specified Accession: S04812 innerSurface SIMPLE_MOLECULE Arachiodonic acid (AA) Long Name: Long name not specified Synonym: Synonym not specified Accession: U05276 Heterodimer Member Info: H2#PROTEIN#H2#P04489##;G-Protein#PROTEIN#G-Protein#P04490##;GDP#SIMPLE_MOLECULE#GDP#S04814## transmembrane SIMPLE_MOLECULE GDP PROTEIN p8 PROTEIN p1 Long Name: Long name not specified Synonym: Synonym not specified Accession: U05274 Heterodimer Member Info: H2#PROTEIN#H2#P04489##;G-Protein#PROTEIN#G-Protein#P04490##;histamine#SIMPLE_MOLECULE#histamine#S04811##;GDP#SIMPLE_MOLECULE#GDP#S04814## transmembrane SIMPLE_MOLECULE GDP PROTEIN p8 PROTEIN p1 SIMPLE_MOLECULE histamine Long Name: gastric acid secretion Synonym: Synonym not specified Accession: U05279 inside PHENOTYPE gastric acid secretion Long Name: prostaglandin secretion/mucosal defense Synonym: Synonym not specified Accession: U05278 inside PHENOTYPE prostaglandin secretion/mucosal defense STATE_TRANSITION s10 s8 0.3333333333333339,-4.996003610813204E-16 0.6666666666666679,3.885780586188048E-16 a12 a9 a8 STATE_TRANSITION s88 s88 0.3333333333333339,-1.6653345369377348E-16 0.666666666666667,5.551115123125783E-17 a11 a10 a9 STATE_TRANSITION s60 s60 0.3333333333333339,-2.220446049250313E-15 0.6666666666666661,-3.9968028886505635E-15 a7 a8 a6 HETERODIMER_ASSOCIATION s1,s94 s99 0.3333333333333335,2.7755575615628914E-17 0.6666666666666667,1.3877787807814457E-16 0.3333333333333336,-4.440892098500626E-16 0.6666666666666669,-4.440892098500626E-16 0.3333333333333335,-1.1102230246251565E-16 0.6666666666666667,-2.220446049250313E-16 0.21613918403748966,0.3412069948961395 a1 a41 a47 a29 a31 a30 DISSOCIATION s99 s19,s6 0.3333333333333335,-2.220446049250313E-16 0.6666666666666665,-5.551115123125783E-16 0.33333333333333304,0.0 0.666666666666667,0.0 0.06882561562086664,-0.015449165150725919 0.24171484162094892,-0.019950352898643442 0.33333333333333304,0.3333333333333335 a47 a5 a26 a6 a4 KNOWN_TRANSITION_OMITTED s88 s100 0.33333333333333337,0.0 0.6666666666666667,-4.440892098500626E-16 a10 a48 KNOWN_TRANSITION_OMITTED s25 s102 0.33333333333333404,1.7763568394002505E-15 0.666666666666668,0.0 a32 a50 UNKNOWN_INHIBITION s6 s25 0.07336869585577688,-0.6210201307850642 0.8892112016952711,-0.476465265726957 a6 a32