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<![CDATA[
Amino sugars such as N-acetylglucosamine, N-acetylmannosamine and N-acetylneuraminic acid serve multiple roles in biology. In bacteria these amino sugars are components of the peptidoglycan layer and outer membrane lipopolysaccharide layer of bacteria cell walls. They also can serve as a source of carbon and nitrogen for energy production. 
Website=www.biocyc.org/Ecoli/Pathways/
free text=Voet and Voet  (textbook)  Biochemistry
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</annotation>
</species>
<species compartment="default" id="s18" initialAmount="0.0" name="Fructose-6-_br_phosphate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Fructose-6-phosphate
Synonym:  Synonym not specified
Accession:  S03851
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Fructose-6-_br_phosphate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s19" initialAmount="0.0" name="glutamine">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  glutamine
Synonym:  Synonym not specified
Accession:  S03842
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>glutamine</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s20" initialAmount="0.0" name="glutamate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  glutamate
Synonym:  Synonym not specified
Accession:  S03856
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>glutamate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s21" initialAmount="0.0" name="NH_sub_3">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  NH3
Synonym:  Synonym not specified
Accession:  S03841
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>NH_sub_3</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s22" initialAmount="0.0" name="fructose-6-phosphate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  fructose-6-phosphate
Synonym:  Synonym not specified
Accession:  S03853
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>fructose-6-phosphate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s23" initialAmount="0.0" name="N-acetylneuraminate_br_lyase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  N-acetylneuraminate lyase
Synonym:  Synonym not specified
Accession:  P03040
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p1</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r1"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s24" initialAmount="0.0" name="N-acetylmannosamine_br_kinase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  N-acetylmannosamine kinase
Synonym:  Synonym not specified
Accession:  P03038
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p2</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r2"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s25" initialAmount="0.0" name="N-acetylmannosamine-_br_6-phospate epimerase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  N-acetylmannosamine-6-phospate epimerase
Synonym:  Synonym not specified
Accession:  P03037
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p3</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r3"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s26" initialAmount="0.0" name="N-acetylglucosamine-6-_br_phosphate deacetylase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  N-acetylglucosamine-6-phosphate deacetylase
Synonym:  Synonym not specified
Accession:  P03036
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p4</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r4"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s27" initialAmount="0.0" name="Fructose-6-phosphate_br_aminotransferase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Fructose-6-phosphate aminotransferase
Synonym:  Synonym not specified
Accession:  P03042
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p5</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r5"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s28" initialAmount="0.0" name="Glucosamine-6-phosphate_br_deaminase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Glucosamine-6-phosphate deaminase
Synonym:  Synonym not specified
Accession:  P03041
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p6</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r6"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s29" initialAmount="0.0" name="Phosphoglucosamine_br_mutase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Phosphoglucosamine mutase
Synonym:  Synonym not specified
Accession:  P03035
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p7</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r7"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s30" initialAmount="0.0" name="Glucosamine-1-phosphate_br_acetyltransferase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Glucosamine-1-phosphate acetyltransferase
Synonym:  Synonym not specified
Accession:  P03039
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p8</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r8"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s31" initialAmount="0.0" name="N-acetylglucosamine-1-_br_phosphate uridyltransferase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  N-acetylglucosamine-1-phosphate uridyltransferase
Synonym:  Synonym not specified
Accession:  P03043
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p9</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r9"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s4" initialAmount="0.0" name="N-acetyl-D-mannosamine-_br_6-phosphate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  N-acetyl-D-mannose-amine-6-phosphate
Synonym:  Synonym not specified
Accession:  S03860
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>N-acetyl-D-mannosamine-_br_6-phosphate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s12" initialAmount="0.0" name="N-acetylglucosamine-_br_1-phosphate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  N-acetyl-glucos-amine-1-phosphate
Synonym:  Synonym not specified
Accession:  S03843
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>N-acetylglucosamine-_br_1-phosphate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
</listOfSpecies>
<listOfReactions>
<reaction id="r1" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s1</celldesigner:baseReactants>
<celldesigner:baseProducts>s2</celldesigner:baseProducts>
<celldesigner:listOfProductLinks>
<celldesigner:productLink alias="a3" product="s3" targetLineIndex="-1,1"/>
</celldesigner:listOfProductLinks>
<celldesigner:editPoints>0.3333333333333333,-4.440892098500626E-16 0.6666666666666665,-8.881784197001252E-16</celldesigner:editPoints>
<celldesigner:listOfModification>
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</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s1">
<annotation>
<celldesigner:alias>a1</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s2">
<annotation>
<celldesigner:alias>a2</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s3">
<annotation>
<celldesigner:alias>a3</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s23">
<annotation>
<celldesigner:alias>a24</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r2" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s2</celldesigner:baseReactants>
<celldesigner:baseProducts>s4</celldesigner:baseProducts>
<celldesigner:listOfReactantLinks>
<celldesigner:reactantLink alias="a5" reactant="s5" targetLineIndex="-1,1"/>
</celldesigner:listOfReactantLinks>
<celldesigner:listOfProductLinks>
<celldesigner:productLink alias="a6" product="s6" targetLineIndex="-1,1"/>
</celldesigner:listOfProductLinks>
<celldesigner:editPoints>0.33333333333333337,-8.881784197001252E-16 0.6666666666666666,-4.440892098500626E-16</celldesigner:editPoints>
<celldesigner:listOfModification>
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</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s2">
<annotation>
<celldesigner:alias>a2</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s5">
<annotation>
<celldesigner:alias>a5</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
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<annotation>
<celldesigner:alias>a4</celldesigner:alias>
</annotation>
</speciesReference>
<speciesReference species="s6">
<annotation>
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</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s24">
<annotation>
<celldesigner:alias>a25</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r3" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s4</celldesigner:baseReactants>
<celldesigner:baseProducts>s7</celldesigner:baseProducts>
<celldesigner:editPoints>0.3333333333333335,-8.881784197001252E-16 0.6666666666666665,-8.881784197001252E-16</celldesigner:editPoints>
<celldesigner:listOfModification>
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</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s4">
<annotation>
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</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s7">
<annotation>
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</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s25">
<annotation>
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</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r4" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s7</celldesigner:baseReactants>
<celldesigner:baseProducts>s10</celldesigner:baseProducts>
<celldesigner:listOfReactantLinks>
<celldesigner:reactantLink alias="a8" reactant="s8" targetLineIndex="-1,0"/>
</celldesigner:listOfReactantLinks>
<celldesigner:listOfProductLinks>
<celldesigner:productLink alias="a9" product="s9" targetLineIndex="-1,1"/>
</celldesigner:listOfProductLinks>
<celldesigner:editPoints>0.3333333333333339,0.0 0.666666666666667,0.0</celldesigner:editPoints>
<celldesigner:listOfModification>
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</annotation>
<listOfReactants>
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<annotation>
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</annotation>
</speciesReference>
<speciesReference species="s8">
<annotation>
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</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
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<annotation>
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</annotation>
</speciesReference>
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<annotation>
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</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s26">
<annotation>
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</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r5" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s10</celldesigner:baseReactants>
<celldesigner:baseProducts>s18</celldesigner:baseProducts>
<celldesigner:listOfReactantLinks>
<celldesigner:reactantLink alias="a19" reactant="s19" targetLineIndex="-1,0"/>
</celldesigner:listOfReactantLinks>
<celldesigner:listOfProductLinks>
<celldesigner:productLink alias="a20" product="s20" targetLineIndex="-1,1"/>
</celldesigner:listOfProductLinks>
<celldesigner:editPoints>0.33333333333333337,4.440892098500626E-16 0.6666666666666667,1.1102230246251565E-15</celldesigner:editPoints>
<celldesigner:listOfModification>
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</annotation>
<listOfReactants>
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<annotation>
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</annotation>
</speciesReference>
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<annotation>
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</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
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<annotation>
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</annotation>
</speciesReference>
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<annotation>
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</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
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<annotation>
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</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r6" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s10</celldesigner:baseReactants>
<celldesigner:baseProducts>s22</celldesigner:baseProducts>
<celldesigner:listOfReactantLinks>
<celldesigner:reactantLink alias="a21" reactant="s8" targetLineIndex="-1,0"/>
</celldesigner:listOfReactantLinks>
<celldesigner:listOfProductLinks>
<celldesigner:productLink alias="a22" product="s21" targetLineIndex="-1,1"/>
</celldesigner:listOfProductLinks>
<celldesigner:editPoints>0.33333333333333326,1.3322676295501878E-15 0.6666666666666667,1.7763568394002505E-15</celldesigner:editPoints>
<celldesigner:listOfModification>
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</annotation>
<listOfReactants>
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<annotation>
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</speciesReference>
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<annotation>
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</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
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<annotation>
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</annotation>
</speciesReference>
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<annotation>
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</annotation>
</speciesReference>
</listOfProducts>
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<annotation>
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</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r7" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
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<celldesigner:baseProducts>s11</celldesigner:baseProducts>
<celldesigner:editPoints>0.3333333333333339,-4.440892098500626E-16 0.666666666666667,0.0</celldesigner:editPoints>
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</annotation>
<listOfReactants>
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<annotation>
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</speciesReference>
</listOfReactants>
<listOfProducts>
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<annotation>
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</annotation>
</speciesReference>
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