2.3 inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive Long Name: Cholesterol ester Synonym: Synonym not specified Accession: S03326 inside SIMPLE_MOLECULE Cholesterol_space_ester Long Name: Cholesterol Synonym: Synonym not specified Accession: S03335 inside SIMPLE_MOLECULE Cholesterol Long Name: 22beta-hydroxycholesterol Synonym: Synonym not specified Accession: S03330 inside SIMPLE_MOLECULE 22_beta__minus_hydroxycholesterol Long Name: Pregnenolone Synonym: Synonym not specified Accession: S03342 inside SIMPLE_MOLECULE Pregnenolone Long Name: Progesterone Synonym: Synonym not specified Accession: S03329 inside SIMPLE_MOLECULE Progesterone Long Name: 20alpha/22beta dihydroxycholesterol Synonym: Synonym not specified Accession: S03341 inside SIMPLE_MOLECULE 20_alpha__slash_22_beta__space_dihydroxycholesterol Long Name: H2O Synonym: Synonym not specified Accession: S03347 inside SIMPLE_MOLECULE H_sub_2_endsub_O Long Name: fatty acid Synonym: Synonym not specified Accession: S03348 inside SIMPLE_MOLECULE fatty_space_acid Long Name: CoA-SH Synonym: Synonym not specified Accession: S03338 inside SIMPLE_MOLECULE CoA_minus_SH Long Name: Acyl-CoA Synonym: Synonym not specified Accession: S03334 inside SIMPLE_MOLECULE Acyl_minus_CoA Long Name: Cholesterol esterase Synonym: Cholesterol ester synthase,Triterpenol esterase Accession: P02830 inside PROTEIN p1 Long Name: Cholesterol acyltransferase Synonym: ACAT,acyl-CoA:cholesterol acyl transferase Accession: P02829 inside PROTEIN p2 Long Name: NADPH+H+ Synonym: Synonym not specified Accession: S03336 inside SIMPLE_MOLECULE NADPH_plus_H_super__plus__endsuper_ Long Name: O2 Synonym: Synonym not specified Accession: U04369 inside ION O_sub_2 Long Name: NADP+ Synonym: Synonym not specified Accession: S03325 inside SIMPLE_MOLECULE NADP_super__plus_ Long Name: Cholesterol monooxygenase Synonym: Synonym not specified Accession: P02835 inside PROTEIN p3 Long Name: Isocaproic aldehyde Synonym: Synonym not specified Accession: S03328 inside SIMPLE_MOLECULE Isocaproic_br_aldehyde Long Name: Steroid Delta-isomerase Synonym: Synonym not specified Accession: P02832 inside PROTEIN p4 Long Name: 3-beta-hydroxy-delta(5)-steroid dehydrogenase Synonym: 3-beta-hydroxy-5-ene steroid dehydrogenase,Progesterone reductase Accession: P02837 inside PROTEIN p5 Long Name: 7alpha/20alpha-dihydroxy-cholesterol Synonym: Synonym not specified Accession: S03350 inside SIMPLE_MOLECULE 7_alpha__slash_20_alpha__minus_dihydroxy_minus__br_cholesterol Long Name: 17alpha-hydroxy-prognenolone Synonym: Synonym not specified Accession: S03346 inside SIMPLE_MOLECULE 17_alpha__minus_hydroxy_minus__br_prognenolone Long Name: 17alpha-hydroxy-progesterone Synonym: Synonym not specified Accession: S03332 inside SIMPLE_MOLECULE 17_alpha__minus_hydroxy_minus__br_progesterone Long Name: Steroid 17alpha-monooxygenase Synonym: Synonym not specified Accession: P02838 inside PROTEIN p6 Long Name: Dehydroepiandro-sterone Synonym: Synonym not specified Accession: S03327 inside SIMPLE_MOLECULE Dehydroepiandro_minus__br_sterone Long Name: 4-Androstene-3/17-dione Synonym: Synonym not specified Accession: S03343 inside SIMPLE_MOLECULE 4_minus_Androstene_minus__br_3_slash_17_minus_dione Long Name: Hydroxyprogesterone aldolase Synonym: Synonym not specified Accession: P02836 inside PROTEIN p7 Long Name: 2-Methyl heptanone Synonym: Synonym not specified Accession: S03337 inside SIMPLE_MOLECULE 2_minus_Methyl_br_heptanone Long Name: Dihydroepiandro-sterone sulfate Synonym: Synonym not specified Accession: S03323 inside SIMPLE_MOLECULE Dihydroepiandro_minus__br_sterone_space_sulfate Long Name: H2SO4 Synonym: Synonym not specified Accession: S03333 inside SIMPLE_MOLECULE H_sub_2_endsub_SO_sub_4 Long Name: Sterylsulfatase Synonym: Synonym not specified Accession: P02839 inside PROTEIN p8 Long Name: 16alpha-hydroxydehydro-epiandrosterone Synonym: Synonym not specified Accession: S03351 inside SIMPLE_MOLECULE 16_alpha__minus_hydroxydehydro_minus__br_epiandrosterone Long Name: 3beta/17beta-Dihydroxy-5-androstene Synonym: Synonym not specified Accession: S03345 inside SIMPLE_MOLECULE 3_beta__slash_17_beta__minus_Dihydroxy_minus_5_minus__br_androstene Long Name: Testosterone Synonym: Synonym not specified Accession: S03324 inside SIMPLE_MOLECULE Testosterone Long Name: 3beta-Hydroxysteroid dehydrogenase Synonym: Synonym not specified Accession: P02833 inside PROTEIN p9 Long Name: Steroid 16alpha-hydroxylase Synonym: Synonym not specified Accession: P02831 inside PROTEIN p10 Long Name: 16alpha-hydroxyestrone Synonym: Synonym not specified Accession: S03340 inside SIMPLE_MOLECULE 16_alpha__minus_hydroxyestrone Long Name: 19-hydroxy-testosterone Synonym: Synonym not specified Accession: S03331 inside SIMPLE_MOLECULE 19_minus_hydroxy_minus__br_testosterone Long Name: 19-hydroxyandrost-4-ene-3/17-dione Synonym: Synonym not specified Accession: S03344 inside SIMPLE_MOLECULE 19_minus_hydroxyandrost_minus__br_4_minus_ene_minus_3_slash_17_minus_dione Long Name: Aromatase Synonym: Synonym not specified Accession: P02828 inside PROTEIN p11 Long Name: Steroid 19-hydroxylase Synonym: Synonym not specified Accession: P02834 inside PROTEIN p12 Long Name: Estriol Synonym: Synonym not specified Accession: S03322 inside SIMPLE_MOLECULE Estriol Long Name: Estradiol-17beta Synonym: Synonym not specified Accession: S03349 inside SIMPLE_MOLECULE Estradiol_minus_17_beta Long Name: Estrone Synonym: Synonym not specified Accession: S03339 inside SIMPLE_MOLECULE Estrone Long Name: Estradiol 17beta-dehydrogenase Synonym: Synonym not specified Accession: P02826 inside PROTEIN p13 Long Name: Steroid 16alpha-hydroxylase Synonym: Synonym not specified Accession: P02831 inside PROTEIN p14 STATE_TRANSITION s1 s2 0.33333333333333304,0.0 0.6666666666666667,4.440892098500626E-16 a1 a7 a2 a8 a11 STATE_TRANSITION s2 s1 0.3333333333333335,-2.220446049250313E-16 0.6666666666666669,0.0 a2 a10 a1 a9 a12 STATE_TRANSITION s2 s3 0.33333333333333326,4.440892098500626E-16 0.6666666666666665,0.0 a2 a13 a14 a3 a16 a15 a17 STATE_TRANSITION s3 s4 0.3333333333333335,2.220446049250313E-16 0.6666666666666665,-2.220446049250313E-16 a3 a18 a19 a4 a20 a21 a22 STATE_TRANSITION s4 s5 0.3333333333333335,0.0 0.6666666666666665,0.0 a4 a23 a24 a5 a25 a26 a27 a28 STATE_TRANSITION s5 s6 0.33333333333333304,2.220446049250313E-16 0.6666666666666661,-2.220446049250313E-16 a5 a6 a29 a30 a31 STATE_TRANSITION s2 s20 0.33333333333333326,0.0 0.6666666666666665,0.0 a2 a32 STATE_TRANSITION s5 s21 0.30336414010085644,0.2493226191561866 0.7338052527368562,0.007039779264959023 a5 a36 a35 a33 a37 a38 a39 STATE_TRANSITION s6 s22 0.33333333333333326,-4.440892098500626E-16 0.6666666666666665,-1.3322676295501878E-15 a6 a42 a41 a34 a43 a44 a39 STATE_TRANSITION s6 s5 0.3333333333333339,0.0 0.6666666666666661,0.0 a6 a5 a45 a30 a31 STATE_TRANSITION s21 s22 0.3333333333333339,-4.440892098500626E-16 0.6666666666666679,-4.440892098500626E-16 a33 a34 a48 a46 a47 STATE_TRANSITION s22 s21 0.33333333333333215,0.0 0.666666666666667,4.440892098500626E-16 a34 a33 a49 a46 a47 STATE_TRANSITION s21 s24 0.3333333333333335,0.0 0.6666666666666667,0.0 a33 a52 a53 a50 a54 a55 a60 STATE_TRANSITION s22 s25 0.33333333333333326,-1.7763568394002505E-15 0.6666666666666665,-3.552713678800501E-15 a34 a56 a57 a51 a58 a59 a60 DISSOCIATION s20 s24,s27 0.3333333333333339,5.551115123125783E-17 0.6666666666666665,5.551115123125783E-17 0.33333333333333304,2.220446049250313E-16 0.6666666666666665,-2.220446049250313E-16 0.33333333333333326,-1.7763568394002505E-15 0.6666666666666672,-1.7763568394002505E-15 0.43227111295356146,0.010015630916553109 a32 a50 a61 STATE_TRANSITION s28 s24 0.33333333333333326,-4.440892098500626E-16 0.6666666666666667,0.0 a62 a63 a50 a64 a65 STATE_TRANSITION s24 s31 0.33333333333333326,0.0 0.6666666666666665,0.0 a50 a70 a71 a66 a72 a73 a85 STATE_TRANSITION s24 s32 0.33333333333333304,-1.7763568394002505E-15 0.666666666666667,-2.6645352591003757E-15 a50 a74 a67 a75 a84 STATE_TRANSITION s25 s33 0.3333333333333326,-1.7763568394002505E-15 0.6666666666666665,-3.9968028886505635E-15 a51 a76 a68 a77 a84 STATE_TRANSITION s24 s25 0.3333333333333335,0.0 0.6666666666666661,8.881784197001252E-16 a50 a51 a81 a82 a83 STATE_TRANSITION s25 s24 0.3333333333333339,0.0 0.666666666666667,8.881784197001252E-16 a51 a50 a78 a82 a83 STATE_TRANSITION s32 s33 0.33333333333333304,8.881784197001252E-16 0.6666666666666665,0.0 a67 a68 a80 a83 a82 STATE_TRANSITION s33 s32 0.33333333333333304,0.0 0.6666666666666665,0.0 a68 a67 a79 a83 a82 STATE_TRANSITION s31 s36 0.33333333333333304,-2.220446049250313E-16 0.6666666666666665,-6.661338147750939E-16 a66 a86 a97 STATE_TRANSITION s33 s37 0.3333333333333335,0.0 0.6666666666666667,8.881784197001252E-16 a68 a93 a94 a87 a95 a96 a97 a98 STATE_TRANSITION s25 s38 0.034680883947297625,-0.07059681184018851 1.081872950627347,-0.15185430223044416 a51 a90 a89 a88 a91 a92 a97 a98 STATE_TRANSITION s36 s41 0.3333333333333339,4.440892098500626E-16 0.666666666666667,6.661338147750939E-16 a86 a112 a99 a111 a113 STATE_TRANSITION s37 s42 0.33333333333333304,3.552713678800501E-15 0.6666666666666661,7.105427357601002E-15 a87 a104 a103 a100 a105 a106 a102 STATE_TRANSITION s38 s43 0.3333333333333339,-8.881784197001252E-16 0.6666666666666679,-1.3322676295501878E-15 a88 a108 a107 a101 a109 a110 a102 STATE_TRANSITION s42 s43 0.33333333333333304,-8.881784197001252E-16 0.6666666666666665,0.0 a100 a101 a115 a116 a117 STATE_TRANSITION s43 s42 0.3333333333333339,-8.881784197001252E-16 0.6666666666666674,0.0 a101 a100 a114 a116 a117 STATE_TRANSITION s43 s36 0.23638943199426699,-0.12616001378837738 0.635881118322803,0.024638645932810954 a101 a119 a120 a86 a122 a121 a118