No pathway definition 2.5 Long Name: GTP Synonym: Synonym not specified Accession: S06110 s22 SIMPLE_MOLECULE GTP Long Name: G-protein Synonym: Synonym not specified Accession: P06002 s22 PROTEIN p11 Long Name: GDP Synonym: Synonym not specified Accession: S06108 s31 SIMPLE_MOLECULE GDP Long Name: G-protein Synonym: Synonym not specified Accession: P06002 s31 PROTEIN p11 Long Name: GDP Synonym: Synonym not specified Accession: S06108 s57 SIMPLE_MOLECULE GDP Long Name: G-protein Synonym: Synonym not specified Accession: P06002 s57 PROTEIN p11 Long Name: dynorphin Synonym: Synonym not specified Accession: P06003 s54 PROTEIN p25 Long Name: dynorphin Synonym: Synonym not specified Accession: P06003 s57 PROTEIN p25 Long Name: opioid receptor, kappa Synonym: OPRK Accession: P05998 s31 PROTEIN p6 Long Name: opioid receptor, kappa Synonym: OPRK Accession: P05998 s54 PROTEIN p6 Long Name: opioid receptor, kappa Synonym: OPRK Accession: P05998 s57 PROTEIN p6 SQUARE_CLOSEUP_SOUTH SQUARE SQUARE SQUARE SQUARE_CLOSEUP_NORTH active inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive active inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive default magnocellular cells in hypothalamus secretory vesicle endoplasmic reticulum nucleus Long Name: SNARE COMPLEX Synonym: Long Name: SNARE COMPLEX Accession: P05996 transmembrane PROTEIN p24 Long Name: prodynorphin Synonym: Synonym not specified Accession: P05997 inside PROTEIN p14 Long Name: dehydration or salt loading stress Synonym: Synonym not specified Accession: U06196 inside PHENOTYPE dehydration or salt loading stress Long Name: vasopressin Synonym: ADH,Long Name: vasopressin,antidiuretic hormone Accession: P06000 inside PROTEIN p2 Long Name: vasopressin Synonym: ADH,Long Name: vasopressin,antidiuretic hormone Accession: P06000 inside PROTEIN p2 Long Name: prepropressophysin Synonym: Synonym not specified Accession: G06050 inside GENE gn2 Long Name: prepropressophysin Synonym: Synonym not specified Accession: G06048 inside RNA rn2 Long Name: antidiuretic effects Synonym: Synonym not specified Accession: U06195 inside PHENOTYPE antidiuretic effects Long Name: Complex (GTP/G-protein) Synonym: Synonym not specified Accession: U06191 Heterodimer Member Info: GTP#SIMPLE_MOLECULE#GTP#S06110##;G-protein#PROTEIN#G-protein#P06002## inside COMPLEX Complex_br_(GTP/G-protein) Long Name: GDP Synonym: Synonym not specified Accession: S06108 inside SIMPLE_MOLECULE GDP Long Name: GTP Synonym: Synonym not specified Accession: S06110 inside SIMPLE_MOLECULE GTP Long Name: ATP Synonym: Synonym not specified Accession: S06109 inside SIMPLE_MOLECULE ATP Long Name: cAMP Synonym: Synonym not specified Accession: S06111 inside SIMPLE_MOLECULE cAMP Long Name: Complex (GDP/G-protein/ Sigma Receptor) Synonym: Synonym not specified Accession: U06192 Heterodimer Member Info: GDP#SIMPLE_MOLECULE#GDP#S06108##;Kappa Receptor#PROTEIN#opioid receptor, kappa#P05998#OPRK#;G-protein#PROTEIN#G-protein#P06002## transmembrane COMPLEX Complex_br_(GDP/G-protein/_br_Sigma Receptor) Long Name: Complex (Sigma Receptor/endorphins (morphine like)) Synonym: Synonym not specified Accession: U06193 Heterodimer Member Info: Kappa Receptor#PROTEIN#opioid receptor, kappa#P05998#OPRK#;dynorphin#PROTEIN#dynorphin#P06003## transmembrane COMPLEX Complex_br_(Sigma Receptor/endorphins (morphine like)) Long Name: Complex (GDP/G-protein/ Sigma Receptor/endorphins (morphine like)) Synonym: Synonym not specified Accession: U06194 Heterodimer Member Info: GDP#SIMPLE_MOLECULE#GDP#S06108##;Kappa Receptor#PROTEIN#opioid receptor, kappa#P05998#OPRK#;G-protein#PROTEIN#G-protein#P06002##;dynorphin#PROTEIN#dynorphin#P06003## transmembrane COMPLEX Complex_br_(GDP/G-protein/_br_Sigma Receptor/endorphins (morphine like)) Long Name: dynorphin Synonym: Synonym not specified Accession: P06003 inside PROTEIN p25 Long Name: dynorphin Synonym: Synonym not specified Accession: P06003 inside PROTEIN p25 Long Name: preprodynorphin Synonym: Synonym not specified Accession: G06047 inside GENE gn1 Long Name: preprodynorphin Synonym: Synonym not specified Accession: G06049 inside RNA rn1 Long Name: provasopressin Synonym: Synonym not specified Accession: P05999 inside PROTEIN pr12 Long Name: analgesic pain relief Synonym: Synonym not specified Accession: U06197 inside PHENOTYPE analgesic_br_pain relief Long Name: adenylate cyclase Synonym: Long Name: AC,adenylate cyclase,adenylate cyclase 2,adenylate cyclase 7,adenylyl cyclase Accession: P06001 inside PROTEIN p7 TRANSCRIPTIONAL_ACTIVATION 0.3333333333333335,0.0 0.666666666666667,-5.551115123125783E-17 a10 a11 a12 TRANSPORT 0.5045246980000302,-0.06627788539380175 0.7031413994003168,-0.06580022812597708 a16 a17 a2 TRANSCRIPTIONAL_ACTIVATION 0.3306233062330626,0.005879937587253359 0.6531165311653122,0.009788946374311713 a13 a14 a12 KNOWN_TRANSITION_OMITTED 0.22463105107285952,0.0915092727371031 0.4818953198262921,0.16751579809286213 a11 a6 KNOWN_TRANSITION_OMITTED 0.3001949885147628,-0.1485811450067671 0.6786097571976386,-0.08186905631000307 a17 a18 STATE_TRANSITION 0.33333333333333304,-4.440892098500626E-16 0.6666666666666679,-4.440892098500626E-16 a26 a28 a29 STATE_TRANSITION 0.33333333333333304,8.881784197001252E-16 0.6666666666666661,8.881784197001252E-16 a30 a29 a22 KNOWN_TRANSITION_OMITTED 0.3333333333333335,8.881784197001252E-16 0.6666666666666663,8.881784197001252E-16 a28 a18 HETERODIMER_ASSOCIATION 0.3246610160900856,0.011980014946941273 a43 a32 a49 DISSOCIATION 0.33333333333333337,-8.881784197001252E-16 0.6666666666666666,0.0 0.3333333333333339,8.881784197001252E-16 0.6666666666666679,8.881784197001252E-16 0.3333333333333339,0.0 0.666666666666667,8.881784197001252E-16 0.3333333333333339,0.33333333333333304 a49 a25 a46 a22 a23 TRANSPORT sa37 a43 a2 KNOWN_TRANSITION_OMITTED a6 sa37 KNOWN_TRANSITION_OMITTED a14 sa38 KNOWN_TRANSITION_OMITTED sa38 a16 KNOWN_TRANSITION_OMITTED a28 sa39