No pathway definition 2.5 Long Name: GTP Synonym: Synonym not specified Accession: S06114 s7 SIMPLE_MOLECULE GTP Long Name: G-protein Synonym: Synonym not specified Accession: P06012 s7 PROTEIN p11 Long Name: GDP Synonym: Synonym not specified Accession: S06112 s11 SIMPLE_MOLECULE GDP Long Name: G-protein Synonym: Synonym not specified Accession: P06012 s11 PROTEIN p11 Long Name: GDP Synonym: Synonym not specified Accession: S06112 s26 SIMPLE_MOLECULE GDP Long Name: G-protein Synonym: Synonym not specified Accession: P06012 s26 PROTEIN p11 Long Name: beta-Endorphin Synonym: Long Name: beta-Endorphin Accession: P06006 s26 PROTEIN p16 Long Name: beta-Endorphin Synonym: Long Name: beta-Endorphin Accession: P06006 s27 PROTEIN p16 Long Name: Anaelgesia Synonym: Synonym not specified Accession: U06206 s35 PHENOTYPE Anaelgesia Long Name: hyperpolarization Synonym: Synonym not specified Accession: U06204 s35 PHENOTYPE hyperpolarization Long Name: opioid receptor, delta or mu Synonym: Synonym not specified Accession: P06004 s11 PROTEIN p6 Long Name: opioid receptor, delta or mu Synonym: Synonym not specified Accession: P06004 s26 PROTEIN p6 Long Name: opioid receptor, delta or mu Synonym: Synonym not specified Accession: P06004 s27 PROTEIN p6 SQUARE SQUARE SQUARE_CLOSEUP_SOUTH SQUARE_CLOSEUP_NORTH active inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive active inactive inactive inactive active inactive inactive inactive inactive inactive inactive active inactive inactive inactive inactive inactive inactive inactive inactive Golgi apparatus synaptic vesicle neurons of nucleus tractus solitarius (also in anterior pituitary, neocortex, basal ganglia, amygldala) noxious stimuli sensitive cells around the central canal in spinal cord Long Name: beta-Endorphin Synonym: Long Name: beta-Endorphin Accession: P06006 inside PROTEIN p16 Long Name: stress response Synonym: Synonym not specified Accession: U06205 inside PHENOTYPE stress response Long Name: SNARE COMPLEX Synonym: Long Name: SNARE COMPLEX Accession: P06005 transmembrane PROTEIN p24 Long Name: corticotropin Synonym: Corticotropin ,Long Name: ACTH Accession: P06008 inside PROTEIN p17 Long Name: proopiomelanocortin Synonym: Corticotropin,Gamma-MSH,Lipotropin,Long Name: proopiomelanocortin,Melanocyte stimulating hormone,Melanotropin,POC Accession: P06010 inside PROTEIN p12 Long Name: beta-Endorphin Synonym: Long Name: beta-Endorphin Accession: P06006 inside PROTEIN p16 Long Name: corticotropin Synonym: Corticotropin ,Long Name: ACTH Accession: P06008 inside PROTEIN p17 Long Name: alpha-MSH Synonym: Long Name: alpha-MSH Accession: P06007 inside PROTEIN p18 Long Name: alpha-MSH Synonym: Long Name: alpha-MSH Accession: P06007 inside PROTEIN p18 Long Name: Complex (GTP/G-protein) Synonym: Synonym not specified Accession: U06198 Heterodimer Member Info: GTP#SIMPLE_MOLECULE#GTP#S06114##;G-protein#PROTEIN#G-protein#P06012## inside COMPLEX Complex_br_(GTP/G-protein) Long Name: GTP Synonym: Synonym not specified Accession: S06114 inside SIMPLE_MOLECULE GTP Long Name: GDP Synonym: Synonym not specified Accession: S06112 inside SIMPLE_MOLECULE GDP Long Name: cAMP Synonym: Synonym not specified Accession: S06115 inside SIMPLE_MOLECULE cAMP Long Name: ATP Synonym: Synonym not specified Accession: S06113 inside SIMPLE_MOLECULE ATP Long Name: adenylate cyclase Synonym: Long Name: AC,adenylate cyclase,adenylate cyclase 2,adenylate cyclase 7,adenylyl cyclase Accession: P06011 inside PROTEIN p7 Long Name: Complex (GDP/G-protein/ Sigma, Mu, Kappa) Synonym: Synonym not specified Accession: U06199 Heterodimer Member Info: Mu or Delta receptor#PROTEIN#opioid receptor, delta or mu#P06004##;GDP#SIMPLE_MOLECULE#GDP#S06112##;G-protein#PROTEIN#G-protein#P06012## transmembrane COMPLEX Complex_br_(GDP/G-protein/_br_Sigma, Mu, Kappa) Long Name: Complex (GDP/G-protein/ Mu or Kappa/beta-Endorphin) Synonym: Synonym not specified Accession: U06200 Heterodimer Member Info: Mu or Delta receptor#PROTEIN#opioid receptor, delta or mu#P06004##;GDP#SIMPLE_MOLECULE#GDP#S06112##;beta-Endorphin#PROTEIN#beta-Endorphin#P06006#Long Name: beta-Endorphin#;G-protein#PROTEIN#G-protein#P06012## transmembrane COMPLEX Complex_br_(GDP/G-protein/_br_Mu or Kappa/beta-Endorphin) Long Name: Complex (Mu or Kappa/beta-Endorphin) Synonym: Synonym not specified Accession: U06201 Heterodimer Member Info: Mu or Delta receptor#PROTEIN#opioid receptor, delta or mu#P06004##;beta-Endorphin#PROTEIN#beta-Endorphin#P06006#Long Name: beta-Endorphin# transmembrane COMPLEX Complex_br_(Mu or Kappa/beta-Endorphin) Long Name: K+ Synonym: Synonym not specified Accession: U06203 inside ION K+ Long Name: K+ Synonym: Synonym not specified Accession: U06203 inside ION K+ Long Name: Complex (Anaelgesia/hyperpolarization) Synonym: Synonym not specified Accession: U06202 Heterodimer Member Info: hyperpolarization#PHENOTYPE#hyperpolarization#U06204##;Anaelgesia#PHENOTYPE#Anaelgesia#U06206## inside COMPLEX Complex_br_(Anaelgesia/hyperpolarization) Long Name: K+ channel Synonym: Kcnk3,Long Name: K+ channel,Potassium channel subfamily K member 3,Potassium channel subfamily K member 9,TASK-1,TASK-3,TWIK Accession: P06009 transmembrane PROTEIN p2 DISSOCIATION 0.3333333333333337,-8.881784197001252E-16 0.6666666666666665,8.881784197001252E-16 0.2894460706123261,-0.01945447109270315 0.5788921412246513,-0.03890894218540497 0.3788733741320618,-0.017053317159928083 0.7577467482641254,-0.034106634319857276 0.29063206820271903,0.3828449282926947 a9 a8 a7 a6 TRANSPORT 0.48704901748271734,-0.06088404639725242 0.8559212268718404,-0.05155334982825699 a8 a5 a3 TRANSPORT 0.34940465815494903,-0.05327644509419249 0.7446551955880243,-0.02580513740296242 a6 a4 a3 KNOWN_TRANSITION_OMITTED 0.33333333333333304,0.0 0.666666666666667,4.440892098500626E-16 a4 a2 KNOWN_TRANSITION_OMITTED 0.33333333333333304,-1.1102230246251565E-16 0.666666666666667,0.0 a5 a2 TRANSPORT 0.37704261583838816,-0.050716262543532675 0.6908981133191476,-0.02990605698898552 a7 a1 a3 STATE_TRANSITION 0.33333333333333304,-4.440892098500626E-16 0.6666666666666679,-4.440892098500626E-16 a19 a16 a17 STATE_TRANSITION 0.33333333333333304,8.881784197001252E-16 0.6666666666666661,8.881784197001252E-16 a18 a17 a11 STATE_TRANSITION 0.3333333333333348,0.0 0.6666666666666674,1.7763568394002505E-15 a36 a35 a11 TRANSPORT a37 a34 a35 STATE_TRANSITION a35 a40 KNOWN_TRANSITION_OMITTED 0.33333333333333304,4.440892098500626E-16 0.6666666666666665,6.661338147750939E-16 a16 a40 HETERODIMER_ASSOCIATION 0.20285028765447244,0.1935920818918746 a1 a15 a32 DISSOCIATION 0.33333333333333304,-1.7763568394002505E-15 0.6666666666666661,0.0 0.3333333333333144,5.329070518200751E-15 0.6666666666666572,5.329070518200751E-15 0.33333333333333326,1.7763568394002505E-15 0.6666666666666676,1.7763568394002505E-15 0.3333333333333304,0.33333333333333304 a32 a13 a33 a11 a14