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<![CDATA[
Vitamin B6 is a collective name fore three substituted pyridines - pyridoxal, pyridoxol, and pyridoxamine.  Pyridoxal carries an aldehyde group (-CHO) at C-4.  Pyridoxol is the corresponding alcohol (-CH2OH), and pyridoxamine the homologous amine (-CH2NH2).  The active form of vitamin B6, pyridoxal phosphate, is the most important coenzyme in amino acid metabolism.  Glycogen phosphorylase, the enzyme catalyzing glycogen degradation, also contains pyridoxal phosphate.  Vitamin B6 deficiency is very rare.
Website=KEGG - Kyoto Encyclopedia of Genes and Genomes http://www.genome.jp/kegg/
free text=Biochemiscal Pathways - An Atlas of Biochemistry and Molecular Biology Edited by Gerhard Michal
free text=Color Atlas of Biochemistry by Jan Koolman and Klaus-Heinrich Rohm
free text=Human Metabolism by Ramsey Bronk
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<celldesigner:protein id="p68" name="3-Hydroxy-2-methylpyridine_br_carboxylate dioxygenase" type="GENERIC"/>
<celldesigner:protein id="p69" name="3-Hydroxy-2-methylpyridine_br_4,5-dicarboxylate 4-decarboxylase" type="GENERIC"/>
<celldesigner:protein id="p70" name="Pyridoxalactonase" type="GENERIC"/>
<celldesigner:protein id="p73" name="Pyridoxal_br_4-dehydrogenase" type="GENERIC"/>
<celldesigner:protein id="p74" name="Pyridoxal_br_oxiadase" type="GENERIC"/>
<celldesigner:protein id="p75" name="Pyridoxamine_br_phosphate oxidase" type="GENERIC"/>
<celldesigner:protein id="p76" name="Pyrodoxamine_br_pyruvate transaminase" type="GENERIC"/>
<celldesigner:protein id="p77" name="Pyridoxamine_br_oxaloacetate transaminase" type="GENERIC"/>
<celldesigner:protein id="p78" name="Pyridoxamine_br_phosphate transaminase" type="GENERIC"/>
<celldesigner:protein id="p79" name="Pyridoxal_br_kinase" type="GENERIC"/>
<celldesigner:protein id="p81" name="Pyridoxine_br_4-dehydrogenase" type="GENERIC"/>
<celldesigner:protein id="p83" name="Pyridoxine_br_4-oxidase" type="GENERIC"/>
<celldesigner:protein id="p84" name="2-(hydroxymethyl)_br_3-(acetamidomethylene)_br_succinate hydrolase" type="GENERIC"/>
<celldesigner:protein id="p85" name="Pyridoxine_br_5-dehydrogenase" type="GENERIC"/>
<celldesigner:protein id="p86" name="5-pyridoxate dioxygenase" type="GENERIC"/>
<celldesigner:protein id="p87" name="Phosphoserine_br_transaminase" type="GENERIC"/>
<celldesigner:protein id="p88" name="Threonine_br_synthase" type="GENERIC"/>
<celldesigner:protein id="p89" name="4-hydroxythreonine-4-phosphate_br_dehydrogenase" type="GENERIC"/>
</celldesigner:listOfProteins>
<celldesigner:listOfBlockDiagrams/>
</annotation>
<listOfCompartments>
<compartment id="default" size="1.0"/>
<compartment id="c4" name="Butaonate Metabolism" outside="default" size="1.0">
<annotation>
<celldesigner:name>Butaonate Metabolism</celldesigner:name>
</annotation>
</compartment>
<compartment id="c6" name="Glyoxylate and _br_Dicarboxylate Metabolism" outside="default" size="1.0">
<annotation>
<celldesigner:name>Glyoxylate and _br_Dicarboxylate Metabolism</celldesigner:name>
</annotation>
</compartment>
<compartment id="c7" name="Pentose Phosphate Pathway" outside="default" size="1.0">
<annotation>
<celldesigner:name>Pentose Phosphate Pathway</celldesigner:name>
</annotation>
</compartment>
</listOfCompartments>
<listOfSpecies>
<species compartment="c4" id="s3" initialAmount="0.0" name="Succinate_br_semialdehyde">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Succinate semialdehyde
Synonym:  Synonym not specified
Accession:  S04333
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Succinate_br_semialdehyde</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s194" initialAmount="0.0" name="2-(Acetamidomethylene)_br_succinate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  2-(Acetamidomethylene) succinate
Synonym:  Synonym not specified
Accession:  S04325
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>2-(Acetamidomethylene)_br_succinate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s197" initialAmount="0.0" name="3-Hydroxy-2_br_methylpyridine-_br_5-carboxylate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  3-Hydroxy-2 methylpyridine-5-carboxylate
Synonym:  Synonym not specified
Accession:  S04319
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>3-Hydroxy-2_br_methylpyridine-_br_5-carboxylate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s198" initialAmount="0.0" name="3-Hydroxy-2_br_methylpyridine-_br_4,5-dicarboxylate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  3-Hydroxy-2 methylpyridine-4,5-dicarboxylate
Synonym:  Synonym not specified
Accession:  S04330
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>3-Hydroxy-2_br_methylpyridine-_br_4,5-dicarboxylate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s200" initialAmount="0.0" name="2-Methyl-3-Hydroxy-_br_5-formylpyridine-_br_4-carboxylate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  2-Methyl-3-Hydroxy-5-formylpyridine-4-carboxylate
Synonym:  Synonym not specified
Accession:  S04310
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>2-Methyl-3-Hydroxy-_br_5-formylpyridine-_br_4-carboxylate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s202" initialAmount="0.0" name="2-(Acetamidomethylene)_br_succinate hydrolase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  2-(Acetamidomethylene) succinate hydrolase
Synonym:  Synonym not specified
Accession:  P03233
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p66</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r87"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s204" initialAmount="0.0" name="3-Hydroxy-2-methylpyridine_br_carboxylate dioxygenase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  3-Hydroxy-2-methylpyridine carboxylate dioxygenase
Synonym:  Synonym not specified
Accession:  P03230
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p68</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r91"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s205" initialAmount="0.0" name="3-Hydroxy-2-methylpyridine_br_4,5-dicarboxylate 4-decarboxylase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  3-Hydroxy-2-methylpyridine 4,5-dicarboxylate 4-decarboxylase
Synonym:  Synonym not specified
Accession:  P03237
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p69</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r92"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s206" initialAmount="0.0" name="Excretion">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Excretion
Synonym:  Synonym not specified
Accession:  U04370
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>UNKNOWN</celldesigner:class>
<celldesigner:name>Excretion</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s215" initialAmount="0.0" name="4-Pyridoxate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  4-Pyridoxate
Synonym:  Synonym not specified
Accession:  S04326
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>4-Pyridoxate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s216" initialAmount="0.0" name="4-Pyridoxolactone">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  4-Pyridoxolactone
Synonym:  Synonym not specified
Accession:  S04311
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>4-Pyridoxolactone</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s217" initialAmount="0.0" name="Pyridoxamine">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Pyridoxamine
Synonym:  Synonym not specified
Accession:  S04327
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Pyridoxamine</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s218" initialAmount="0.0" name="Pyridoxal">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Pyridoxal
Synonym:  Synonym not specified
Accession:  S04331
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Pyridoxal</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s219" initialAmount="0.0" name="Pyridoxalactonase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Pyridoxalactonase
Synonym:  Synonym not specified
Accession:  P03239
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p70</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r97"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s222" initialAmount="0.0" name="Pyridoxal_br_4-dehydrogenase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Pyridoxal 4-dehydrogenase
Synonym:  Synonym not specified
Accession:  P03243
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p73</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r99"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s223" initialAmount="0.0" name="Pyridoxal_br_oxiadase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Pyridoxal oxiadase
Synonym:  Synonym not specified
Accession:  P03226
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p74</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r106"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s224" initialAmount="0.0" name="Pyridoxamine_br_phosphate oxidase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Pyridoxamine phosphate oxidase
Synonym:  Synonym not specified
Accession:  P03236
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p75</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r105"/>
<celldesigner:catalyzed reaction="r110"/>
<celldesigner:catalyzed reaction="r112"/>
<celldesigner:catalyzed reaction="r122"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s225" initialAmount="0.0" name="Pyrodoxamine_br_pyruvate transaminase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Pyrodoxamine pyruvate transaminase
Synonym:  Synonym not specified
Accession:  P03228
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p76</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r110"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s226" initialAmount="0.0" name="Pyridoxamine_br_oxaloacetate transaminase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Pyridoxamine oxaloacetate transaminase
Synonym:  Synonym not specified
Accession:  P03238
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p77</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r110"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s227" initialAmount="0.0" name="Pyridoxamine_br_phosphate transaminase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Pyridoxamine phosphate transaminase
Synonym:  Synonym not specified
Accession:  P03234
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p78</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r110"/>
<celldesigner:catalyzed reaction="r111"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s228" initialAmount="0.0" name="Pyridoxal_br_kinase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Pyridoxal kinase
Synonym:  Synonym not specified
Accession:  P03244
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p79</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r124"/>
<celldesigner:catalyzed reaction="r126"/>
<celldesigner:catalyzed reaction="r128"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s230" initialAmount="0.0" name="D-Glutamate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  D-Glutamate
Synonym:  Synonym not specified
Accession:  S04317
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>D-Glutamate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s229" initialAmount="0.0" name="2-Oxoglutarate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  2-Oxoglutarate
Synonym:  Synonym not specified
Accession:  S04313
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>2-Oxoglutarate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s231" initialAmount="0.0" name="Pyruvate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Pyruvate
Synonym:  Synonym not specified
Accession:  S04307
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Pyruvate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s232" initialAmount="0.0" name="D-Alanine">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  D-Alanine
Synonym:  Synonym not specified
Accession:  S04314
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>D-Alanine</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s234" initialAmount="0.0" name="Pyridoxine">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Pyridoxine
Synonym:  Synonym not specified
Accession:  S04318
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Pyridoxine</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s236" initialAmount="0.0" name="Pyridoxine_br_phosphate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Pyridoxine phosphate
Synonym:  Synonym not specified
Accession:  S04335
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Pyridoxine_br_phosphate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s237" initialAmount="0.0" name="Pyridoxamine_br_5-phosphate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Pyridoxamine 5-phosphate
Synonym:  Synonym not specified
Accession:  S04312
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Pyridoxamine_br_5-phosphate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s238" initialAmount="0.0" name="Pyridoxal_br_5-phosphate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Pyridoxal 5-phosphate
Synonym:  Synonym not specified
Accession:  S04321
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Pyridoxal_br_5-phosphate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s240" initialAmount="0.0" name="Pyridoxine_br_4-dehydrogenase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Pyridoxine 4-dehydrogenase
Synonym:  Synonym not specified
Accession:  P03229
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p81</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r122"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s242" initialAmount="0.0" name="Pyridoxine_br_4-oxidase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Pyridoxine 4-oxidase
Synonym:  Synonym not specified
Accession:  P03231
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p83</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r122"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="c6" id="s244" initialAmount="0.0" name="Glycoaldehyde">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Glycoaldehyde
Synonym:  Synonym not specified
Accession:  S04320
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Glycoaldehyde</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s246" initialAmount="0.0" name="Isopyridoxal">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Isopyridoxal
Synonym:  Synonym not specified
Accession:  S04308
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>Isopyridoxal</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s247" initialAmount="0.0" name="5-Pyridoxolactone">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  5-Pyridoxolactone
Synonym:  Synonym not specified
Accession:  S04334
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>5-Pyridoxolactone</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s248" initialAmount="0.0" name="3-Hydroxy-4-hydroxymethyl-_br_2-methylpyridine_br_5-carboxylate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  3-Hydroxy-4-hydroxymethyl-2-methylpyridine 5-carboxylate
Synonym:  Synonym not specified
Accession:  S04322
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>3-Hydroxy-4-hydroxymethyl-_br_2-methylpyridine_br_5-carboxylate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s249" initialAmount="0.0" name="2-(Acetamidomethylene)_br_3-hydroxymethyl_br_succinate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  2-(Acetamidomethylene) 3-hydroxymethyl succinate
Synonym:  Synonym not specified
Accession:  S04323
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>2-(Acetamidomethylene)_br_3-hydroxymethyl_br_succinate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s250" initialAmount="0.0" name="_Alpha_-Hydroxymethyl_br_succinate semialdehyde">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Alpha-Hydroxymethyl succinate semialdehyde
Synonym:  Synonym not specified
Accession:  S04309
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>_Alpha_-Hydroxymethyl_br_succinate semialdehyde</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="c7" id="s251" initialAmount="0.0" name="D-Erythrose_br_4-phosphate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  D-Erythrose 4-phosphate
Synonym:  Synonym not specified
Accession:  S04316
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>D-Erythrose_br_4-phosphate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s252" initialAmount="0.0" name="4-Phospho_br_D-erythronate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  4-Phospho D-erythronate
Synonym:  Synonym not specified
Accession:  S04329
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>4-Phospho_br_D-erythronate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s253" initialAmount="0.0" name="2-Oxo-3-hydroxy_br_4-phosphobutaonate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  2-Oxo-3-hydroxy 4-phosphobutaonate
Synonym:  Synonym not specified
Accession:  S04332
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>2-Oxo-3-hydroxy_br_4-phosphobutaonate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s255" initialAmount="0.0" name="O-Phospho_br_4-hydroxy L-threonine">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  O-Phospho 4-hydroxy L-threonine
Synonym:  Synonym not specified
Accession:  S04328
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>O-Phospho_br_4-hydroxy L-threonine</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s256" initialAmount="0.0" name="4-Hydroxy L-threonine">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  4-Hydroxy L-threonine
Synonym:  Synonym not specified
Accession:  S04315
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>4-Hydroxy L-threonine</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s257" initialAmount="0.0" name="3-Amino-_br_2-oxopropyl_br_phosphate">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  3-Amino-2-oxopropyl phosphate
Synonym:  Synonym not specified
Accession:  S04324
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>SIMPLE_MOLECULE</celldesigner:class>
<celldesigner:name>3-Amino-_br_2-oxopropyl_br_phosphate</celldesigner:name>
</celldesigner:speciesIdentity>
</annotation>
</species>
<species compartment="default" id="s258" initialAmount="0.0" name="2-(hydroxymethyl)_br_3-(acetamidomethylene)_br_succinate hydrolase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  2-(hydroxymethyl) 3-(acetamidomethylene) succinate hydrolase
Synonym:  Synonym not specified
Accession:  P03240
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p84</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r135"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s259" initialAmount="0.0" name="Pyridoxine_br_5-dehydrogenase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Pyridoxine 5-dehydrogenase
Synonym:  Synonym not specified
Accession:  P03241
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p85</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r131"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s260" initialAmount="0.0" name="5-pyridoxate dioxygenase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  5-pyridoxate dioxygenase
Synonym:  Synonym not specified
Accession:  P03232
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p86</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r134"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s261" initialAmount="0.0" name="Phosphoserine_br_transaminase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Phosphoserine transaminase
Synonym:  Synonym not specified
Accession:  P03227
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p87</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r144"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s262" initialAmount="0.0" name="Threonine_br_synthase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  Threonine synthase
Synonym:  Synonym not specified
Accession:  P03242
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p88</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r145"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
<species compartment="default" id="s263" initialAmount="0.0" name="4-hydroxythreonine-4-phosphate_br_dehydrogenase">
<notes>
<html xmlns="http://www.w3.org/1999/xhtml">
<!--Notes by CellDesigner-->
<body>
Long Name:  4-hydroxythreonine-4-phosphate dehydrogenase
Synonym:  Synonym not specified
Accession:  P03235
</body>
</html>
</notes>
<annotation>
<celldesigner:positionToCompartment>inside</celldesigner:positionToCompartment>
<celldesigner:speciesIdentity>
<celldesigner:class>PROTEIN</celldesigner:class>
<celldesigner:proteinReference>p89</celldesigner:proteinReference>
</celldesigner:speciesIdentity>
<celldesigner:listOfCatalyzedReactions>
<celldesigner:catalyzed reaction="r147"/>
</celldesigner:listOfCatalyzedReactions>
</annotation>
</species>
</listOfSpecies>
<listOfReactions>
<reaction id="r87" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s194</celldesigner:baseReactants>
<celldesigner:baseProducts>s3</celldesigner:baseProducts>
<celldesigner:editPoints>0.3333333333333335,2.220446049250313E-16 0.666666666666667,0.0</celldesigner:editPoints>
<celldesigner:listOfModification>
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</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s194">
<annotation>
<celldesigner:alias>a195</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s3">
<annotation>
<celldesigner:alias>a3</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s202">
<annotation>
<celldesigner:alias>a200</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r91" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s197</celldesigner:baseReactants>
<celldesigner:baseProducts>s194</celldesigner:baseProducts>
<celldesigner:editPoints>0.33333333333333326,-1.2323475573339238E-14 0.6666666666666666,-2.4646951146678475E-14</celldesigner:editPoints>
<celldesigner:listOfModification>
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</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s197">
<annotation>
<celldesigner:alias>a196</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s194">
<annotation>
<celldesigner:alias>a195</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s204">
<annotation>
<celldesigner:alias>a202</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r92" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s198</celldesigner:baseReactants>
<celldesigner:baseProducts>s197</celldesigner:baseProducts>
<celldesigner:editPoints>0.33333333333333304,1.5432100042289676E-14 0.6666666666666665,3.064215547965432E-14</celldesigner:editPoints>
<celldesigner:listOfModification>
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</celldesigner:listOfModification>
</annotation>
<listOfReactants>
<speciesReference species="s198">
<annotation>
<celldesigner:alias>a197</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s197">
<annotation>
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</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s205">
<annotation>
<celldesigner:alias>a203</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r93" reversible="false">
<annotation>
<celldesigner:reactionType>KNOWN_TRANSITION_OMITTED</celldesigner:reactionType>
<celldesigner:baseReactants>s200</celldesigner:baseReactants>
<celldesigner:baseProducts>s198</celldesigner:baseProducts>
<celldesigner:editPoints>0.3333333333333335,1.5432100042289676E-14 0.666666666666667,3.086420008457935E-14</celldesigner:editPoints>
</annotation>
<listOfReactants>
<speciesReference species="s200">
<annotation>
<celldesigner:alias>a198</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s198">
<annotation>
<celldesigner:alias>a197</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
</reaction>
<reaction id="r94" reversible="false">
<annotation>
<celldesigner:reactionType>KNOWN_TRANSITION_OMITTED</celldesigner:reactionType>
<celldesigner:baseReactants>s215</celldesigner:baseReactants>
<celldesigner:baseProducts>s200</celldesigner:baseProducts>
<celldesigner:editPoints>0.3333333333333339,-1.1102230246251565E-15 0.6666666666666661,-2.220446049250313E-15</celldesigner:editPoints>
</annotation>
<listOfReactants>
<speciesReference species="s215">
<annotation>
<celldesigner:alias>a192</celldesigner:alias>
</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s200">
<annotation>
<celldesigner:alias>a198</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
</reaction>
<reaction id="r96" reversible="false">
<annotation>
<celldesigner:reactionType>KNOWN_TRANSITION_OMITTED</celldesigner:reactionType>
<celldesigner:baseReactants>s215</celldesigner:baseReactants>
<celldesigner:baseProducts>s206</celldesigner:baseProducts>
<celldesigner:editPoints>0.3333333333333339,0.0 0.666666666666667,-3.552713678800501E-15</celldesigner:editPoints>
</annotation>
<listOfReactants>
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<annotation>
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</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s206">
<annotation>
<celldesigner:alias>a204</celldesigner:alias>
</annotation>
</speciesReference>
</listOfProducts>
</reaction>
<reaction id="r97" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s216</celldesigner:baseReactants>
<celldesigner:baseProducts>s215</celldesigner:baseProducts>
<celldesigner:editPoints>0.33333333333333326,0.0 0.6666666666666667,0.0</celldesigner:editPoints>
<celldesigner:listOfModification>
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</annotation>
<listOfReactants>
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<annotation>
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</annotation>
</speciesReference>
</listOfReactants>
<listOfProducts>
<speciesReference species="s215">
<annotation>
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</annotation>
</speciesReference>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="s219">
<annotation>
<celldesigner:alias>a210</celldesigner:alias>
</annotation>
</modifierSpeciesReference>
</listOfModifiers>
</reaction>
<reaction id="r98" reversible="false">
<annotation>
<celldesigner:reactionType>STATE_TRANSITION</celldesigner:reactionType>
<celldesigner:baseReactants>s218</celldesigner:baseReactants>
<celldesigner:baseProducts>s216</celldesigner:baseProducts>
<celldesigner:editPoints>0.3333333333333335,1.1102230246251565E-16 0.666666666666667,3.3306690738754696E-16</celldesigner:editPoints>
</annotation>
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