No pathway definition 2.5 Long Name: GTP Synonym: Synonym not specified Accession: S06066 s2 SIMPLE_MOLECULE GTP Long Name: G-Protein (s) Synonym: Synonym not specified Accession: P05977 s2 PROTEIN p8 Long Name: GDP Synonym: Synonym not specified Accession: S06064 s24 SIMPLE_MOLECULE GDP Long Name: G-Protein (s) Synonym: Synonym not specified Accession: P05977 s24 PROTEIN p8 Long Name: GPCR (s) Synonym: Long Name: GPCR (s) Accession: P05975 s24 PROTEIN p2 Long Name: GDP Synonym: Synonym not specified Accession: S06064 s26 SIMPLE_MOLECULE GDP Long Name: G-Protein (i) Synonym: Synonym not specified Accession: P05974 s26 PROTEIN p4 Long Name: GPCR (i) Synonym: G-Protein coupled receptor,Long Name: GPCR (i) Accession: P05973 s26 PROTEIN p1 Long Name: GTP Synonym: Synonym not specified Accession: S06066 s28 SIMPLE_MOLECULE GTP Long Name: G-Protein (i) Synonym: Synonym not specified Accession: P05974 s28 PROTEIN p4 Long Name: cAMP response element binding protein Synonym: Long Name: CREB Accession: P05971 s35 PROTEIN p13 Long Name: preproenkephalin Synonym: Synonym not specified Accession: G06045 s35 GENE gn1 SQUARE_CLOSEUP_NORTH active inactive inactive active inactive inactive active inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive active inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive neuron Long Name: GDP Synonym: Synonym not specified Accession: S06064 inside SIMPLE_MOLECULE GDP Long Name: adenylate cyclase Synonym: Long Name: AC,adenylate cyclase,adenylate cyclase 2,adenylate cyclase 7,adenylyl cyclase Accession: P05978 inside PROTEIN p3 Long Name: GTP Synonym: Synonym not specified Accession: S06066 inside SIMPLE_MOLECULE GTP Long Name: ATP Synonym: Synonym not specified Accession: S06065 inside SIMPLE_MOLECULE ATP Long Name: cAMP Synonym: Synonym not specified Accession: S06067 inside SIMPLE_MOLECULE cAMP Long Name: Complex (GTP/G-Protein) Synonym: Synonym not specified Accession: U06175 Heterodimer Member Info: G-Protein (s)#PROTEIN#G-Protein (s)#P05977##;GTP#SIMPLE_MOLECULE#GTP#S06066## inside COMPLEX Complex_br_(GTP/G-Protein) Long Name: GPCR (s) Synonym: Long Name: GPCR (s) Accession: P05975 transmembrane PROTEIN p2 Long Name: GPCR (i) Synonym: G-Protein coupled receptor,Long Name: GPCR (i) Accession: P05973 transmembrane PROTEIN p1 Long Name: Complex (GDP/G-Protein (s)/ GPCR (s)) Synonym: Synonym not specified Accession: U06176 Heterodimer Member Info: GDP#SIMPLE_MOLECULE#GDP#S06064##;GPCR (s)#PROTEIN#GPCR (s)#P05975#Long Name: GPCR (s)#;G-Protein (s)#PROTEIN#G-Protein (s)#P05977## transmembrane COMPLEX Complex_br_(GDP/G-Protein (s)/_br_GPCR (s)) Long Name: Complex (GDP/G-Protein (i)/ GPCR (i)) Synonym: Synonym not specified Accession: U06177 Heterodimer Member Info: GPCR (i)#PROTEIN#GPCR (i)#P05973#G-Protein coupled receptor|Long Name: GPCR (i)#;GDP#SIMPLE_MOLECULE#GDP#S06064##;G-Protein (i)#PROTEIN#G-Protein (i)#P05974## transmembrane COMPLEX Complex_br_(GDP/G-Protein (i)/_br_GPCR (i)) Long Name: Complex (GTP/G-Protein (i)) Synonym: Synonym not specified Accession: U06178 Heterodimer Member Info: G-Protein (i)#PROTEIN#G-Protein (i)#P05974##;GTP#SIMPLE_MOLECULE#GTP#S06066## inside COMPLEX Complex_br_(GTP/G-Protein (i)) Long Name: adenylate cyclase Synonym: Long Name: AC,adenylate cyclase,adenylate cyclase 2,adenylate cyclase 7,adenylyl cyclase Accession: P05978 innerSurface PROTEIN p3 Long Name: cAMP response element binding protein Synonym: Long Name: CREB Accession: P05971 inside PROTEIN p13 Long Name: cAMP response element binding protein Synonym: Long Name: CREB Accession: P05971 inside PROTEIN p13 Long Name: PKA Synonym: Long Name: PKA,protein kinase A Accession: P05972 inside PROTEIN p5 Long Name: Enkephalin Synonym: Long Name: Enkephalin Accession: P05976 inside PROTEIN p6 Long Name: Complex (CREB/Protoenkephalin) Synonym: Synonym not specified Accession: U06179 Heterodimer Member Info: CREB#PROTEIN#cAMP response element binding protein#P05971#Long Name: CREB#;preproenkephalin#GENE#preproenkephalin#G06045## inside COMPLEX Complex_br_(CREB/Protoenkephalin) Long Name: Pain relief Analgesia Synonym: Synonym not specified Accession: U06181 inside PHENOTYPE Pain relief_br_Analgesia Long Name: Bind to opioid receptors Synonym: Synonym not specified Accession: U06180 inside PHENOTYPE Bind to opioid receptors Long Name: preproenkephalin mRNA Synonym: Synonym not specified Accession: G06046 inside RNA rn1 Long Name: preproenkephalin Synonym: Synonym not specified Accession: G06045 inside GENE gn1 STATE_TRANSITION 0.3333333333333339,-4.996003610813204E-16 0.6666666666666679,3.885780586188048E-16 a11 a12 a4 STATE_TRANSITION 0.33333333333333304,-8.881784197001252E-16 0.666666666666667,0.0 a5 a4 a2 a47 STATE_TRANSITION 0.33333333333333215,8.881784197001252E-16 0.6666666666666661,0.0 a6 a9 a49 DISSOCIATION 0.3333333333333339,-4.440892098500626E-16 0.6666666666666679,-6.661338147750939E-16 0.33333333333333215,0.0 0.6666666666666661,-1.7763568394002505E-15 0.3333333333333339,8.881784197001252E-16 0.666666666666667,0.0 0.3333333333333339,0.3333333333333333 a44 a46 a24 a47 a37 DISSOCIATION -0.04064568115369127,-0.0053654561822620295 0.47952270793203144,-0.004236520459195647 0.2736637855508107,0.26891674323140347 a35 a8 a19 a2 a3 STATE_TRANSITION 0.33333333333333304,4.440892098500626E-16 0.6666666666666652,8.881784197001252E-16 a48 a49 a12 KNOWN_TRANSITION_OMITTED 0.33333333333333215,4.440892098500626E-16 0.6666666666666679,-4.440892098500626E-16 a51 a52 HETERODIMER_ASSOCIATION 0.33333333333333304,0.0 0.666666666666667,8.881784197001252E-16 0.3754021645560357,0.02650599855667224 0.7508043291120714,0.05301199711334803 0.33333333333333304,0.0 0.6666666666666665,0.0 0.34332480297741075,0.31930787460835786 a9 a57 a54 KNOWN_TRANSITION_OMITTED 0.3333333333333335,4.440892098500626E-16 0.6666666666666667,4.440892098500626E-16 a54 a51 KNOWN_TRANSITION_OMITTED 0.33333333333333304,4.440892098500626E-16 0.6666666666666667,0.0 a52 a59 KNOWN_TRANSITION_OMITTED 0.33333333333333304,-8.881784197001252E-16 0.6666666666666661,-4.440892098500626E-16 a59 a58