2.2 SQUARE_CLOSEUP_NORTHEAST OVAL OVAL inactive inactive inactive inactive active inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive active active active active inactive inactive inactive inactive inactive inactive inactive inactive inactive active inactive nucleus Neuronal axon terminal Synaptic Vessicle Long Name: Glutamate Synonym: Synonym not specified Accession: S01764 inside SIMPLE_MOLECULE Glutamate Long Name: GTP Synonym: Synonym not specified Accession: S01767 inside SIMPLE_MOLECULE GTP Long Name: GDP Synonym: Synonym not specified Accession: S01768 inside SIMPLE_MOLECULE GDP Long Name: Long Name: Long name not specified Synonym: Synonym not specified Accession: U05381 Heterodimer Member Info: Glutamate#SIMPLE_MOLECULE#Glutamate#S01764##;mGluR2/3#PROTEIN#Metabotropic Glutamate Receptor 2, Metabotropic Glutamate Receptor 3#P01048#GRM2|GRM3|mGlu 2|mGlu 3|mGlu2|mGlu3|mGluR2|mGluR3# transmembrane PROTEIN p1 SIMPLE_MOLECULE Glutamate Long Name: cAMP Synonym: Synonym not specified Accession: S01766 inside SIMPLE_MOLECULE cAMP Long Name: ATP Synonym: Synonym not specified Accession: S01765 inside SIMPLE_MOLECULE ATP Long Name: Steps Omitted Synonym: Synonym not specified Accession: U02466 inside PHENOTYPE Steps Omitted Long Name: brain-derived neurotrophic factor Synonym: Synonym not specified Accession: G01540 inside GENE BDNF Long Name: Ca2+ Synonym: Synonym not specified Accession: U02465 inside ION Ca_super_2+ Long Name: Glutamate Synonym: Synonym not specified Accession: S01764 inside SIMPLE_MOLECULE Glutamate Long Name: N-ethylmaleimide-sensitive factor attachment protein receptor Synonym: SNARE Accession: P01049 transmembrane PROTEIN p10 Long Name: Long Name: Metabotropic Glutamate Receptor 2, Metabotropic Glutamate Receptor 3 Synonym: Synonym not specified Accession: U05382 Heterodimer Member Info: G-protein#PROTEIN#G-protein#P01047#Gi#;mGluR2/3#PROTEIN#Metabotropic Glutamate Receptor 2, Metabotropic Glutamate Receptor 3#P01048#GRM2|GRM3|mGlu 2|mGlu 3|mGlu2|mGlu3|mGluR2|mGluR3#;GDP#SIMPLE_MOLECULE#GDP#S01768## transmembrane PROTEIN p1 PROTEIN p11 SIMPLE_MOLECULE GDP Long Name: Calcium Channel Synonym: Ca++ Channel,Ca2+ channel Accession: P01051 transmembrane PROTEIN p7 Long Name: Long Name: Long name not specified Synonym: Synonym not specified Accession: U05383 Heterodimer Member Info: G-protein#PROTEIN#G-protein#P01047#Gi#;GTP#SIMPLE_MOLECULE#GTP#S01767## inside SIMPLE_MOLECULE GTP PROTEIN p11 Long Name: Adenylate Cyclase Synonym: AC Accession: P01052 inside PROTEIN p5 Long Name: Protein Kinase A Synonym: PKA Accession: P01050 inside PROTEIN p6 Long Name: Long Name: Long name not specified Synonym: Synonym not specified Accession: U05380 Heterodimer Member Info: Glutamate#SIMPLE_MOLECULE#Glutamate#S01764##;G-protein#PROTEIN#G-protein#P01047#Gi#;mGluR2/3#PROTEIN#Metabotropic Glutamate Receptor 2, Metabotropic Glutamate Receptor 3#P01048#GRM2|GRM3|mGlu 2|mGlu 3|mGlu2|mGlu3|mGluR2|mGluR3#;GDP#SIMPLE_MOLECULE#GDP#S01768## transmembrane PROTEIN p1 SIMPLE_MOLECULE Glutamate PROTEIN p11 SIMPLE_MOLECULE GDP Long Name: Ca2+ Synonym: Synonym not specified Accession: U02465 inside ION Ca_super_2+ Long Name: Long Name: Long name not specified Synonym: Synonym not specified Accession: U05379 Heterodimer Member Info: Ca2+#ION#Ca2+#U02465##;SNARE Complex#PROTEIN#N-ethylmaleimide-sensitive factor attachment protein receptor#P01049#SNARE# transmembrane PROTEIN p10 ION Ca_super_2+ STATE_TRANSITION s51 s50 0.33333333333333304,-4.440892098500626E-16 0.6666666666666679,-4.440892098500626E-16 a57 a56 TRANSCRIPTIONAL_INHIBITION s54 s53 0.33333333333333215,0.0 0.6666666666666661,-8.881784197001252E-16 a60 a59 STATE_TRANSITION s52 s52 0.33333333333333304,0.0 0.666666666666667,0.0 a58 a82 TRANSPORT s65 s4 0.06713329293607434,-0.2928046960576023 0.6675516051926378,-0.10369512994321539 a71 a4 HETERODIMER_ASSOCIATION s4,s69 s80 0.33333333333333215,0.0 0.6666666666666663,5.551115123125783E-17 0.33333333333333215,0.0 0.6666666666666661,0.0 0.33333333333333304,1.1102230246251565E-16 0.6666666666666665,2.220446049250313E-16 0.3333333333333332,0.3333333333333335 a4 a79 a94 DISSOCIATION s80 s35,s71 0.3333333333333339,-6.661338147750939E-16 0.666666666666667,-4.440892098500626E-16 0.33333333333333304,8.881784197001252E-16 0.6666666666666661,0.0 0.33333333333333215,0.0 0.6666666666666661,8.881784197001252E-16 0.33333333333333304,0.3333333333333335 a94 a19 a37 a84 a23 STATE_TRANSITION s48 s48 0.3333333333333335,8.881784197001252E-16 0.6666666666666661,8.881784197001252E-16 a53 a81 STATE_TRANSITION s55 s55 0.3333333333333335,2.220446049250313E-15 0.666666666666667,4.884981308350689E-15 a61 a83 TRANSPORT s58 s82 0.33333333333333304,-2.220446049250313E-16 0.6666666666666663,0.0 a64 a65 HETERODIMER_ASSOCIATION s61,s82 s85 0.33333333333333925,3.552713678800501E-15 -0.2156625508902934,0.03362246230812094 0.33333333333333304,-6.661338147750939E-16 0.6666666666666661,-6.661338147750939E-16 0.33333333333333304,0.0 0.6666666666666665,-2.220446049250313E-16 0.33333333333333215,0.33333333333333215 a95 a65 a96 KNOWN_TRANSITION_OMITTED s52 s54 0.33333333333333337,0.0 0.6666666666666669,-4.440892098500626E-16 a82 a60