Anandamide is an endocannabinoid. After it is released to the extracellular space from postsynaptic terminal, it binds to the cannabinoid receptor on the presynaptic terminal (see Endogenous cannabinoid signaling pathway). Anandamide is also transported via carrier-mediated uptake into nerve endings and glia. The nature of the carrier or transporter has not been characterized. It is believed to be through a selective process if facilitated diffusion. After anandamide is internalized in nerve endings or glia, it is degraded by fatty acid amide hydrolase (FAAH) into arachidonic acid and ethanolamine. 4.0 SQUARE_CLOSEUP_NORTH inactive inactive inactive inactive inactive active intracellular Long Name: ? Synonym: Synonym not specified Accession: U05873 transmembrane UNKNOWN ? Long Name: anandamide Synonym: Synonym not specified Accession: S05790 inside SIMPLE_MOLECULE anandamide Long Name: arachidonic acid Synonym: Synonym not specified Accession: S05789 inside SIMPLE_MOLECULE arachidonic acid Long Name: ethanolamine Synonym: Synonym not specified Accession: S05788 inside SIMPLE_MOLECULE ethanolamine Long Name: anandamide Synonym: Synonym not specified Accession: S05790 inside SIMPLE_MOLECULE anandamide Long Name: Fatty acid amide hydrolase Synonym: Synonym not specified Accession: P05741 inside PROTEIN pr1 TRANSPORT sa2 sa5 sa1 DISSOCIATION 0.35617418332908846,0.255396216728222 sa5 sa3 sa4 sa6