The biosynthesis of S-adenosylmethionine (SAM). SAM is a cofactor that functions as a methyl group donor for a number of metabolic reactions. Website=www.biocyc.org/Ecoli/Pathways/ free text=Voet and Voet (textbook) Biochemistry 4.0 inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive Long Name: homocysteine Synonym: Synonym not specified Accession: S04120 inside SIMPLE_MOLECULE homocysteine Long Name: methionine Synonym: Synonym not specified Accession: S04124 inside SIMPLE_MOLECULE methionine Long Name: SAM Synonym: Synonym not specified Accession: S04123 inside SIMPLE_MOLECULE SAM Long Name: H2O Synonym: Synonym not specified Accession: S04126 inside SIMPLE_MOLECULE H_sub_2_endsub_O Long Name: ATP Synonym: Synonym not specified Accession: S04119 inside SIMPLE_MOLECULE ATP Long Name: PO4 Synonym: Synonym not specified Accession: S04122 inside SIMPLE_MOLECULE PO_sub_4 Long Name: PPi Synonym: Synonym not specified Accession: S04118 inside SIMPLE_MOLECULE PP_sub_i Long Name: 5-CH3-THF Synonym: Synonym not specified Accession: S04121 inside SIMPLE_MOLECULE 5-CH3-THF Long Name: THF Synonym: Synonym not specified Accession: S04125 inside SIMPLE_MOLECULE THF Long Name: Cobalamin-dependent homocysteine transmethylase Synonym: Synonym not specified Accession: P03142 inside PROTEIN p1 Long Name: S-Adenosyl methionine synthetase Synonym: Synonym not specified Accession: P03143 inside PROTEIN p2 STATE_TRANSITION 0.33333333333333326,0.0 0.6666666666666667,0.0 a1 a8 a2 a9 a10 STATE_TRANSITION 0.33333333333333326,-2.220446049250313E-16 0.6666666666666667,0.0 a2 a4 a5 a3 a6 a7 a11