Cholesterol is the origin of multitude of steroids, which are of high importance in metabolic processes. The common synthesis path starts with the partial removal of the cholesterol side chain, yielding the gestagen progesterone. Removal of the remaining side chain leads to androgens, a further aromatozation of ring A yields estrogens. free text=Biochemical Pathways - An atlas of Biochemistry and Molecular Biology - Gerhard Michal 4.0 inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive Long Name: Cholesterol ester Synonym: Synonym not specified Accession: S03326 inside SIMPLE_MOLECULE Cholesterol_space_ester Long Name: Cholesterol Synonym: Synonym not specified Accession: S03335 inside SIMPLE_MOLECULE Cholesterol Long Name: 22beta-hydroxycholesterol Synonym: Synonym not specified Accession: S03330 inside SIMPLE_MOLECULE 22_beta__minus_hydroxycholesterol Long Name: Pregnenolone Synonym: Synonym not specified Accession: S03342 inside SIMPLE_MOLECULE Pregnenolone Long Name: Progesterone Synonym: Synonym not specified Accession: S03329 inside SIMPLE_MOLECULE Progesterone Long Name: 20alpha/22beta dihydroxycholesterol Synonym: Synonym not specified Accession: S03341 inside SIMPLE_MOLECULE 20_alpha__slash_22_beta__space_dihydroxycholesterol Long Name: H2O Synonym: Synonym not specified Accession: S03347 inside SIMPLE_MOLECULE H_sub_2_endsub_O Long Name: fatty acid Synonym: Synonym not specified Accession: S03348 inside SIMPLE_MOLECULE fatty_space_acid Long Name: CoA-SH Synonym: Synonym not specified Accession: S03338 inside SIMPLE_MOLECULE CoA_minus_SH Long Name: Acyl-CoA Synonym: Synonym not specified Accession: S03334 inside SIMPLE_MOLECULE Acyl_minus_CoA Long Name: Cholesterol esterase Synonym: Cholesterol ester synthase,Triterpenol esterase Accession: P02830 inside PROTEIN p1 Long Name: Cholesterol acyltransferase Synonym: ACAT,acyl-CoA:cholesterol acyl transferase Accession: P02829 inside PROTEIN p2 Long Name: NADPH+H+ Synonym: Synonym not specified Accession: S03336 inside SIMPLE_MOLECULE NADPH_plus_H_super__plus__endsuper_ Long Name: O2 Synonym: Synonym not specified Accession: U04369 inside ION O_sub_2 Long Name: NADP+ Synonym: Synonym not specified Accession: S03325 inside SIMPLE_MOLECULE NADP_super__plus_ Long Name: Cholesterol monooxygenase Synonym: Synonym not specified Accession: P02835 inside PROTEIN p3 Long Name: Isocaproic aldehyde Synonym: Synonym not specified Accession: S03328 inside SIMPLE_MOLECULE Isocaproic_br_aldehyde Long Name: Steroid Delta-isomerase Synonym: Synonym not specified Accession: P02832 inside PROTEIN p4 Long Name: 3-beta-hydroxy-delta(5)-steroid dehydrogenase Synonym: 3-beta-hydroxy-5-ene steroid dehydrogenase,Progesterone reductase Accession: P02837 inside PROTEIN p5 Long Name: 7alpha/20alpha-dihydroxy-cholesterol Synonym: Synonym not specified Accession: S03350 inside SIMPLE_MOLECULE 7_alpha__slash_20_alpha__minus_dihydroxy_minus__br_cholesterol Long Name: 17alpha-hydroxy-prognenolone Synonym: Synonym not specified Accession: S03346 inside SIMPLE_MOLECULE 17_alpha__minus_hydroxy_minus__br_prognenolone Long Name: 17alpha-hydroxy-progesterone Synonym: Synonym not specified Accession: S03332 inside SIMPLE_MOLECULE 17_alpha__minus_hydroxy_minus__br_progesterone Long Name: Steroid 17alpha-monooxygenase Synonym: Synonym not specified Accession: P02838 inside PROTEIN p6 Long Name: Dehydroepiandro-sterone Synonym: Synonym not specified Accession: S03327 inside SIMPLE_MOLECULE Dehydroepiandro_minus__br_sterone Long Name: 4-Androstene-3/17-dione Synonym: Synonym not specified Accession: S03343 inside SIMPLE_MOLECULE 4_minus_Androstene_minus__br_3_slash_17_minus_dione Long Name: Hydroxyprogesterone aldolase Synonym: Synonym not specified Accession: P02836 inside PROTEIN p7 Long Name: 2-Methyl heptanone Synonym: Synonym not specified Accession: S03337 inside SIMPLE_MOLECULE 2_minus_Methyl_br_heptanone Long Name: Dihydroepiandro-sterone sulfate Synonym: Synonym not specified Accession: S03323 inside SIMPLE_MOLECULE Dihydroepiandro_minus__br_sterone_space_sulfate Long Name: H2SO4 Synonym: Synonym not specified Accession: S03333 inside SIMPLE_MOLECULE H_sub_2_endsub_SO_sub_4 Long Name: Sterylsulfatase Synonym: Synonym not specified Accession: P02839 inside PROTEIN p8 Long Name: 16alpha-hydroxydehydro-epiandrosterone Synonym: Synonym not specified Accession: S03351 inside SIMPLE_MOLECULE 16_alpha__minus_hydroxydehydro_minus__br_epiandrosterone Long Name: 3beta/17beta-Dihydroxy-5-androstene Synonym: Synonym not specified Accession: S03345 inside SIMPLE_MOLECULE 3_beta__slash_17_beta__minus_Dihydroxy_minus_5_minus__br_androstene Long Name: Testosterone Synonym: Synonym not specified Accession: S03324 inside SIMPLE_MOLECULE Testosterone Long Name: 3beta-Hydroxysteroid dehydrogenase Synonym: Synonym not specified Accession: P02833 inside PROTEIN p9 Long Name: Steroid 16alpha-hydroxylase Synonym: Synonym not specified Accession: P02831 inside PROTEIN p10 Long Name: 16alpha-hydroxyestrone Synonym: Synonym not specified Accession: S03340 inside SIMPLE_MOLECULE 16_alpha__minus_hydroxyestrone Long Name: 19-hydroxy-testosterone Synonym: Synonym not specified Accession: S03331 inside SIMPLE_MOLECULE 19_minus_hydroxy_minus__br_testosterone Long Name: 19-hydroxyandrost-4-ene-3/17-dione Synonym: Synonym not specified Accession: S03344 inside SIMPLE_MOLECULE 19_minus_hydroxyandrost_minus__br_4_minus_ene_minus_3_slash_17_minus_dione Long Name: Aromatase Synonym: Synonym not specified Accession: P02828 inside PROTEIN p11 Long Name: Steroid 19-hydroxylase Synonym: Synonym not specified Accession: P02834 inside PROTEIN p12 Long Name: Estriol Synonym: Synonym not specified Accession: S03322 inside SIMPLE_MOLECULE Estriol Long Name: Estradiol-17beta Synonym: Synonym not specified Accession: S03349 inside SIMPLE_MOLECULE Estradiol_minus_17_beta Long Name: Estrone Synonym: Synonym not specified Accession: S03339 inside SIMPLE_MOLECULE Estrone Long Name: Estradiol 17beta-dehydrogenase Synonym: Synonym not specified Accession: P02826 inside PROTEIN p13 Long Name: Steroid 16alpha-hydroxylase Synonym: Synonym not specified Accession: P02831 inside PROTEIN p14 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