Panther Pathway: P04386 No pathway definition 4.0 s6 SIMPLE_MOLECULE GTP s6 PROTEIN p8 s19 SIMPLE_MOLECULE histamine s19 PROTEIN p1 s94 SIMPLE_MOLECULE GDP s94 PROTEIN p8 s94 PROTEIN p1 s99 SIMPLE_MOLECULE GDP s99 PROTEIN p8 s99 PROTEIN p1 s99 SIMPLE_MOLECULE histamine SQUARE_CLOSEUP_NORTHEAST active inactive inactive inactive inactive inactive inactive inactive active inactive active inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive inactive SRI International Smooth Muscle (gastric secretory cells) Long Name: histamine Synonym: Synonym not specified Accession: S04811 inside SIMPLE_MOLECULE histamine Long Name: GDP Synonym: Synonym not specified Accession: S04814 inside SIMPLE_MOLECULE GDP Long Name: GTP Synonym: Synonym not specified Accession: S04810 inside SIMPLE_MOLECULE GTP Long Name: Long name not specified Synonym: Synonym not specified Accession: U05277 Heterodimer Member Info: GTP#SIMPLE_MOLECULE#GTP#S04810##;G-Protein#PROTEIN#G-Protein#P04490## inside COMPLEX Complex_br_(GTP/G-Protein) Long Name: cAMP Synonym: Synonym not specified Accession: S04808 inside SIMPLE_MOLECULE cAMP Long Name: ATP Synonym: Synonym not specified Accession: S04807 inside SIMPLE_MOLECULE ATP Long Name: Long name not specified Synonym: Synonym not specified Accession: U05275 Heterodimer Member Info: H2#PROTEIN#H2#P04489##;histamine#SIMPLE_MOLECULE#histamine#S04811## transmembrane COMPLEX Complex_br_(histamine/H2) Long Name: AC Synonym: adenylate cyclase,adenylate cyclase 2,adenylate cyclase 7,adenylyl cyclase Accession: P04492 inside PROTEIN p2 Long Name: PKA Synonym: protein kinase A Accession: P04491 inside PROTEIN p15 Long Name: cimetidine (tagamet) Synonym: Synonym not specified Accession: S04806 inside SIMPLE_MOLECULE cimetidine (tagamet) Long Name: ranitidine (zantac) Synonym: Synonym not specified Accession: S04813 inside SIMPLE_MOLECULE ranitidine (zantac) Long Name: tiotidine Synonym: Synonym not specified Accession: S04809 inside SIMPLE_MOLECULE tiotidine Long Name: Arachiodonic acid (AA) Synonym: Synonym not specified Accession: S04812 inside SIMPLE_MOLECULE Arachiodonic acid (AA) Long Name: Long name not specified Synonym: Synonym not specified Accession: U05276 Heterodimer Member Info: H2#PROTEIN#H2#P04489##;G-Protein#PROTEIN#G-Protein#P04490##;GDP#SIMPLE_MOLECULE#GDP#S04814## transmembrane COMPLEX Complex_br_(GDP/G-Protein/_br_H2) Long Name: Long name not specified Synonym: Synonym not specified Accession: U05274 Heterodimer Member Info: H2#PROTEIN#H2#P04489##;G-Protein#PROTEIN#G-Protein#P04490##;histamine#SIMPLE_MOLECULE#histamine#S04811##;GDP#SIMPLE_MOLECULE#GDP#S04814## transmembrane COMPLEX Complex_br_(GDP/G-Protein/_br_H2/histamine) Long Name: gastric acid secretion Synonym: Synonym not specified Accession: U05279 inside PHENOTYPE gastric acid secretion Long Name: prostaglandin secretion/mucosal defense Synonym: Synonym not specified Accession: U05278 inside PHENOTYPE prostaglandin secretion/mucosal defense STATE_TRANSITION a12 a9 a8 STATE_TRANSITION a11 a10 a9 STATE_TRANSITION a7 a8 a6 HETERODIMER_ASSOCIATION 0.6001787748133016,-0.0030241095504299764 0.3203350277777399,0.4961989727451709 a1 a41 a47 a29 a31 a30 DISSOCIATION 0.2204953988585645,0.002042812453378673 0.7047015230410159,0.004463750277964529 0.3293742764006077,0.2906783143110969 a47 a5 a26 a6 a4 UNKNOWN_INHIBITION a6 a50 PHYSICAL_STIMULATION a10 a48 PHYSICAL_STIMULATION a32 a50