! version: 15.0 ! date: 10/3/2019 PC00175 oxidase PC00176 oxidoreductase 05 PC00191 protease inhibitor PC00095 protein-binding activity modulator 05 PC00196 pyrophosphatase PC00121 hydrolase 08 PC00186 phospholipase PC00143 lipase 01 PC00100 extracellular matrix glycoprotein PC00102 extracellular matrix protein 02 PC00156 microtubule binding motor protein PC00157 microtubule or microtubule-binding cytoskeletal protein 03 PC00091 dehydratase PC00144 lyase 02 PC00202 ribosomal protein PC00263 translational protein 01 PC00177 oxygenase PC00176 oxidoreductase 01 PC00017 DNA topoisomerase PC00009 DNA binding protein 08 PC00048 amylase PC00121 hydrolase 05 PC00221 transketolase PC00220 transferase 04 PC00038 acetyltransferase PC00220 transferase 06 PC00089 decarboxylase PC00144 lyase 04 PC00027 Hsp70 family chaperone PC00072 chaperone 03 PC00051 antimicrobial response protein PC00090 defense/immunity protein 03 PC00160 mutase PC00135 isomerase 02 PC00189 primase PC00031 RNA binding protein 03 PC00121 hydrolase PC00262 metabolite interconversion enzyme 03 PC00081 cysteine protease PC00190 protease 02 PC00216 transaminase PC00220 transferase 08 PC00013 DNA methyltransferase PC00009 DNA binding protein 07 PC00026 Hsp60 family chaperone PC00072 chaperone 02 PC00087 deacetylase PC00121 hydrolase 06 PC00065 carbohydrate kinase PC00137 kinase 02 PC00010 DNA glycosylase PC00009 DNA binding protein 06 PC00130 intermediate filament binding protein PC00129 intermediate filament 01 PC00246 winged helix/forkhead transcription factor PC00116 helix-turn-helix transcription factor 04 PC00025 Hsp100 family chaperone PC00072 chaperone 05 PC00060 calcium-binding protein PC00000 protein class 07 PC00097 esterase PC00121 hydrolase 02 PC00128 interleukin superfamily PC00083 cytokine 01 PC00174 nucleotidyltransferase PC00220 transferase 02 PC00176 oxidoreductase PC00262 metabolite interconversion enzyme 01 PC00150 membrane traffic protein PC00000 protein class 26 PC00200 reverse transcriptase PC00031 RNA binding protein 01 PC00235 vesicle coat protein PC00150 membrane traffic protein 01 PC00253 P53-like transcription factor PC00251 immunoglobulin fold transcription factor 02 PC00259 general transcription factor PC00031 RNA binding protein 12 PC00039 actin and actin related protein PC00041 actin or actin-binding cytoskeletal protein 01 PC00117 heterotrimeric G-protein PC00020 G-protein 01 PC00190 protease PC00260 protein modifying enzyme 03 PC00220 transferase PC00262 metabolite interconversion enzyme 02 PC00255 TATA-binding transcription factor PC00218 DNA-binding transcription factor 08 PC00066 carbohydrate phosphatase PC00181 phosphatase 01 PC00178 paired box transcription factor PC00116 helix-turn-helix transcription factor 02 PC00135 isomerase PC00262 metabolite interconversion enzyme 05 PC00041 actin or actin-binding cytoskeletal protein PC00085 cytoskeletal protein 01 PC00183 phosphatase inhibitor PC00184 phosphatase modulator 02 PC00085 cytoskeletal protein PC00000 protein class 13 PC00173 nucleotide phosphatase PC00181 phosphatase 02 PC00210 storage protein PC00000 protein class 31 PC00093 endodeoxyribonuclease PC00009 DNA binding protein 16 PC00234 ubiquitin-protein ligase PC00260 protein modifying enzyme 04 PC00070 cell junction protein PC00000 protein class 16 PC00071 centromere DNA-binding protein PC00009 DNA binding protein 10 PC00261 histone modifying enzyme PC00077 chromatin/chromatin-binding, or -regulatory protein 01 PC00223 translation factor PC00263 translational protein 02 PC00181 phosphatase PC00121 hydrolase 04 PC00215 transaldolase PC00220 transferase 05 PC00047 aminoacyl-tRNA synthetase PC00263 translational protein 03 PC00180 peroxidase PC00176 oxidoreductase 02 PC00142 ligase PC00262 metabolite interconversion enzyme 06 PC00016 DNA strand-pairing protein PC00009 DNA binding protein 12 PC00222 translation elongation factor PC00223 translation factor 02 PC00147 RNA processing factor PC00031 RNA binding protein 05 PC00006 CREB-related transcription factor PC00056 basic leucine zipper transcription factor 01 PC00096 epimerase/racemase PC00135 isomerase 01 PC00254 Runt transcription factor PC00251 immunoglobulin fold transcription factor 03 PC00198 reductase PC00176 oxidoreductase 04 PC00248 C2H2 zinc finger transcription factor PC00244 zinc finger transcription factor 02 PC00020 G-protein PC00095 protein-binding activity modulator 03 PC00099 exoribonuclease PC00031 RNA binding protein 09 PC00045 amino acid kinase PC00137 kinase 04 PC00152 membrane-bound signaling molecule PC00207 intercellular signal molecule 07 PC00127 interferon superfamily PC00083 cytokine 02 PC00252 Rel homology transcription factor PC00251 immunoglobulin fold transcription factor 01 PC00167 non-receptor serine/threonine protein kinase PC00260 protein modifying enzyme 04 PC00107 globin PC00219 transfer/carrier protein 02 PC00256 SMAD-like transcription factor PC00218 DNA-binding transcription factor 09 PC00163 neurotrophic factor PC00112 growth factor 01 PC00015 DNA polymerase processivity factor PC00009 DNA binding protein 02 PC00083 cytokine PC00207 intercellular signal molecule 01 PC00141 ligand-gated ion channel PC00133 ion channel 05 PC00114 guanylate cyclase PC00079 cyclase 02 PC00171 nucleic acid binding protein PC00000 protein class 09 PC00146 mRNA polyadenylation factor PC00147 RNA processing factor 02 PC00032 RNA helicase PC00031 RNA binding protein 11 PC00024 HMG box transcription factor PC00218 DNA-binding transcription factor 02 PC00011 DNA helicase PC00009 DNA binding protein 17 PC00012 DNA ligase PC00009 DNA binding protein 05 PC00226 scaffold/adaptor protein PC00000 protein class 29 PC00217 transcription cofactor PC00264 gene-specific transcriptional regulator 02 PC00197 transmembrane signal receptor PC00000 protein class 01 PC00126 integrin PC00069 cell adhesion molecule 03 PC00143 lipase PC00121 hydrolase 01 PC00034 SNARE protein PC00150 membrane traffic protein 02 PC00233 tyrosine protein kinase receptor PC00197 transmembrane signal receptor 02 PC00086 damaged DNA-binding protein PC00009 DNA binding protein 11 PC00101 extracellular matrix linker protein PC00102 extracellular matrix protein 03 PC00092 dehydrogenase PC00176 oxidoreductase 03 PC00157 microtubule or microtubule-binding cytoskeletal protein PC00085 cytoskeletal protein 02 PC00185 phosphodiesterase PC00121 hydrolase 03 PC00149 major histocompatibility complex protein PC00090 defense/immunity protein 02 PC00219 transfer/carrier protein PC00000 protein class 11 PC00199 replication origin binding protein PC00009 DNA binding protein 03 PC00195 protein phosphatase PC00260 protein modifying enzyme 02 PC00019 DNA-directed RNA polymerase PC00031 RNA binding protein 02 PC00110 glycosidase PC00121 hydrolase 09 PC00162 neuropeptide PC00179 peptide hormone 01 PC00227 transporter PC00000 protein class 10 PC00120 hydratase PC00144 lyase 03 PC00179 peptide hormone PC00207 intercellular signal molecule 04 PC00113 guanyl-nucleotide exchange factor PC00022 G-protein modulator 01 PC00168 non-receptor tyrosine protein kinase PC00260 protein modifying enzyme 02 PC00112 growth factor PC00207 intercellular signal molecule 03 PC00169 C4 zinc finger nuclear receptor PC00244 zinc finger transcription factor 01 PC00073 chaperonin PC00072 chaperone 01 PC00053 aspartic protease PC00190 protease 05 PC00033 RNA methyltransferase PC00031 RNA binding protein 04 PC00042 acyltransferase PC00220 transferase 09 PC00118 histone PC00009 DNA binding protein 13 PC00028 Hsp90 family chaperone PC00072 chaperone 04 PC00153 metalloprotease PC00190 protease 01 PC00094 endoribonuclease PC00031 RNA binding protein 10 PC00166 non-motor microtubule binding protein PC00157 microtubule or microtubule-binding cytoskeletal protein 02 PC00057 cadherin PC00069 cell adhesion molecule 02 PC00061 calmodulin-related PC00060 calcium-binding protein 01 PC00184 phosphatase modulator PC00095 protein-binding activity modulator 02 PC00104 galactosidase PC00121 hydrolase 11 PC00108 glucosidase PC00121 hydrolase 10 PC00205 serine/threonine protein kinase receptor PC00197 transmembrane signal receptor 03 PC00257 GTPase-activating protein PC00022 G-protein modulator 02 PC00258 secondary carrier transporter PC00227 transporter 03 PC00122 hydroxylase PC00176 oxidoreductase 06 PC00056 basic leucine zipper transcription factor PC00218 DNA-binding transcription factor 04 PC00002 ATP synthase PC00068 primary active transporter 01 PC00228 tubulin PC00157 microtubule or microtubule-binding cytoskeletal protein 01 PC00158 mitochondrial carrier protein PC00258 secondary carrier transporter 03 PC00249 C6 zinc finger transcription factor PC00244 zinc finger transcription factor 03 PC00251 immunoglobulin fold transcription factor PC00218 DNA-binding transcription factor 07 PC00218 DNA-binding transcription factor PC00264 gene-specific transcriptional regulator 01 PC00237 viral or transposable element protein PC00000 protein class 28 PC00203 serine protease PC00190 protease 03 PC00148 RNA splicing factor PC00147 RNA processing factor 03 PC00145 mRNA capping factor PC00147 RNA processing factor 01 PC00133 ion channel PC00227 transporter 01 PC00077 chromatin/chromatin-binding, or -regulatory protein PC00000 protein class 34 PC00247 Trp repressor-like transcription factor PC00116 helix-turn-helix transcription factor 05 PC00211 structural protein PC00000 protein class 30 PC00043 adenylate cyclase PC00079 cyclase 01 PC00140 kinase modulator PC00095 protein-binding activity modulator 01 PC00138 kinase activator PC00140 kinase modulator 01 PC00044 aldolase PC00144 lyase 01 PC00151 membrane trafficking regulatory protein PC00150 membrane traffic protein 03 PC00224 translation initiation factor PC00223 translation factor 01 PC00068 primary active transporter PC00227 transporter 02 PC00172 nucleotide kinase PC00137 kinase 03 PC00260 protein modifying enzyme PC00000 protein class 33 PC00022 G-protein modulator PC00095 protein-binding activity modulator 04 PC00072 chaperone PC00000 protein class 27 PC00155 methyltransferase PC00220 transferase 03 PC00207 intercellular signal molecule PC00000 protein class 02 PC00161 myelin protein PC00211 structural protein 01 PC00090 defense/immunity protein PC00000 protein class 25 PC00088 deaminase PC00121 hydrolase 07 PC00009 DNA binding protein PC00171 nucleic acid binding protein 01 PC00212 surfactant PC00211 structural protein 02 PC00095 protein-binding activity modulator PC00000 protein class 06 PC00264 gene-specific transcriptional regulator PC00000 protein class 08 PC00144 lyase PC00262 metabolite interconversion enzyme 04 PC00021 G-protein coupled receptor PC00197 transmembrane signal receptor 01 PC00123 immunoglobulin PC00090 defense/immunity protein 04 PC00003 ATP-binding cassette (ABC) transporter PC00068 primary active transporter 02 PC00105 gap junction PC00070 cell junction protein 01 PC00139 kinase inhibitor PC00140 kinase modulator 02 PC00262 metabolite interconversion enzyme PC00000 protein class 19 PC00040 actin binding motor protein PC00041 actin or actin-binding cytoskeletal protein 03 PC00074 chemokine PC00083 cytokine 05 PC00079 cyclase PC00144 lyase 05 PC00124 immunoglobulin receptor superfamily PC00090 defense/immunity protein 05 PC00225 translation release factor PC00223 translation factor 03 PC00129 intermediate filament PC00085 cytoskeletal protein 03 PC00263 translational protein PC00000 protein class 20 PC00018 DNA-directed DNA polymerase PC00009 DNA binding protein 01 PC00046 amino acid transporter PC00258 secondary carrier transporter 02 PC00103 extracellular matrix structural protein PC00102 extracellular matrix protein 01 PC00241 voltage-gated ion channel PC00133 ion channel 06 PC00125 immunoglobulin superfamily cell adhesion molecule PC00069 cell adhesion molecule 01 PC00250 MADS box transcription factor PC00218 DNA-binding transcription factor 06 PC00137 kinase PC00220 transferase 01 PC00069 cell adhesion molecule PC00000 protein class 12 PC00031 RNA binding protein PC00171 nucleic acid binding protein 02 PC00102 extracellular matrix protein PC00000 protein class 14 PC00111 glycosyltransferase PC00220 transferase 07 PC00014 DNA photolyase PC00009 DNA binding protein 04 PC00245 Lambda repressor-like transcription factor PC00116 helix-turn-helix transcription factor 03 PC00165 non-motor actin binding protein PC00041 actin or actin-binding cytoskeletal protein 02 PC00119 homeodomain transcription factor PC00116 helix-turn-helix transcription factor 01 PC00098 exodeoxyribonuclease PC00009 DNA binding protein 15 PC00182 phosphatase activator PC00184 phosphatase modulator 01 PC00078 complement component PC00090 defense/immunity protein 01 PC00265 histidine kinase receptor of two-component system PC00197 transmembrane signal receptor 04 PC00214 tight junction PC00070 cell junction protein 02 PC00116 helix-turn-helix transcription factor PC00218 DNA-binding transcription factor 05 PC00208 small GTPase PC00020 G-protein 02 PC00052 apolipoprotein PC00219 transfer/carrier protein 01 PC00244 zinc finger transcription factor PC00218 DNA-binding transcription factor 01 PC00055 basic helix-loop-helix transcription factor PC00218 DNA-binding transcription factor 03