ECOLI|EnsemblGenome=b1158|UniProtKB=P03014	P03014	pinE	PTHR30461:SF2	DNA-INVERTASE FROM LAMBDOID PROPHAGE	SERINE RECOMBINASE PINE-RELATED	catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824	nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310			
ECOLI|EnsemblGenome=b3922|UniProtKB=P32162	P32162	yiiS	PTHR38769:SF1	UPF0381 PROTEIN YFCZ-RELATED	UPF0381 PROTEIN YFCZ-RELATED			cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b3573|UniProtKB=P56256	P56256	ysaA	PTHR42859:SF18	OXIDOREDUCTASE	ELECTRON TRANSPORT PROTEIN YSAA-RELATED				metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2578|UniProtKB=P38101	P38101	eamB	PTHR30086:SF22	ARGININE EXPORTER PROTEIN ARGO	CYSTEINE_O-ACETYLSERINE EFFLUX PROTEIN	amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	organic acid transport#GO:0015849;amino acid transport#GO:0006865;transport#GO:0006810;carboxylic acid transport#GO:0046942;localization#GO:0051179;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;L-amino acid transport#GO:0015807;L-alpha-amino acid transmembrane transport#GO:1902475;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;export from cell#GO:0140352;carboxylic acid transmembrane transport#GO:1905039	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0930|UniProtKB=P0A8M0	P0A8M0	asnS	PTHR22594:SF34	ASPARTYL/LYSYL-TRNA SYNTHETASE	ASPARAGINE--TRNA LIGASE		protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987		translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047	
ECOLI|EnsemblGenome=b3789|UniProtKB=P61887	P61887	rffH	PTHR43532:SF4	GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE	GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE 2	transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740	carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;polysaccharide biosynthetic process#GO:0000271;metabolic process#GO:0008152	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	nucleotidyltransferase#PC00174;metabolite interconversion enzyme#PC00262	O-antigen biosynthesis#P02757>dTDP-glucose pyrophosphorylase#P03046
ECOLI|EnsemblGenome=b0139|UniProtKB=P33129	P33129	htrE	PTHR30451:SF3	OUTER MEMBRANE USHER PROTEIN	OUTER MEMBRANE USHER PROTEIN HTRE-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829	cell adhesion#GO:0007155;cellular process#GO:0009987	membrane#GO:0016020;cell outer membrane#GO:0009279;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;outer membrane#GO:0019867;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313		
ECOLI|EnsemblGenome=b2147|UniProtKB=P25889	P25889	preA	PTHR43073:SF2	DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]	NAD-DEPENDENT DIHYDROPYRIMIDINE DEHYDROGENASE SUBUNIT PREA				oxidoreductase#PC00176;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b1113|UniProtKB=P75954	P75954	ycfS	PTHR30582:SF27	L,D-TRANSPEPTIDASE	L,D-TRANSPEPTIDASE YCFS-RELATED	catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236	macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;cell wall macromolecule biosynthetic process#GO:0044038;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;cell wall organization or biogenesis#GO:0071554;peptidoglycan-based cell wall biogenesis#GO:0009273;peptidoglycan metabolic process#GO:0000270;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;glycosaminoglycan biosynthetic process#GO:0006024;macromolecule metabolic process#GO:0043170;glycosaminoglycan metabolic process#GO:0030203;aminoglycan biosynthetic process#GO:0006023;peptidoglycan biosynthetic process#GO:0009252;aminoglycan metabolic process#GO:0006022;cell wall macromolecule metabolic process#GO:0044036;cell wall biogenesis#GO:0042546	extracellular region#GO:0005576;cellular anatomical structure#GO:0110165	protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260	
ECOLI|EnsemblGenome=b2935|UniProtKB=P27302	P27302	tktA	PTHR43522:SF2	TRANSKETOLASE	TRANSKETOLASE 1-RELATED	transketolase activity#GO:0004802;transketolase or transaldolase activity#GO:0016744;catalytic activity#GO:0003824;transferase activity#GO:0016740	pentose-phosphate shunt#GO:0006098;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing small molecule metabolic process#GO:0055086;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;nucleobase-containing compound metabolic process#GO:0006139	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	transferase#PC00220;transketolase#PC00221;metabolite interconversion enzyme#PC00262	Pentose phosphate pathway#P02762>Transketolase#P03082
ECOLI|EnsemblGenome=b1937|UniProtKB=P0A8T5	P0A8T5	fliE	PTHR34653:SF1	FAMILY NOT NAMED	FLAGELLAR HOOK-BASAL BODY COMPLEX PROTEIN FLIE					
ECOLI|EnsemblGenome=b0440|UniProtKB=P0ACF4	P0ACF4	hupB	PTHR33175:SF14	DNA-BINDING PROTEIN HU	DNA-BINDING PROTEIN HU-BETA	DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110	regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556	intracellular organelle#GO:0043229;bacterial nucleoid#GO:0043590;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;chromosome#GO:0005694;replisome#GO:0030894;replication fork#GO:0005657;nucleoid#GO:0009295;organelle#GO:0043226;protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b3062|UniProtKB=P0AC35	P0AC35	ttdB	PTHR43351:SF3	L(+)-TARTRATE DEHYDRATASE SUBUNIT BETA	L(+)-TARTRATE DEHYDRATASE SUBUNIT BETA				dehydratase#PC00091;lyase#PC00144;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1260|UniProtKB=P0A877	P0A877	trpA	PTHR43406:SF1	TRYPTOPHAN SYNTHASE, ALPHA CHAIN	TRYPTOPHAN SYNTHASE ALPHA CHAIN	catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836	cellular process#GO:0009987;amine metabolic process#GO:0009308;amino acid metabolic process#GO:0006520;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;proteinogenic amino acid biosynthetic process#GO:0170038;carboxylic acid biosynthetic process#GO:0046394;indole-containing compound metabolic process#GO:0042430;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;aromatic amino acid biosynthetic process#GO:0009073;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	lyase#PC00144;metabolite interconversion enzyme#PC00262	Tryptophan biosynthesis#P02783>Tryptophan synthase A#P03207
ECOLI|EnsemblGenome=b2539|UniProtKB=Q47140	Q47140	hcaF	PTHR41534:SF1	BLR3401 PROTEIN	3-PHENYLPROPIONATE_CINNAMIC ACID DIOXYGENASE SUBUNIT BETA		cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;cellular response to xenobiotic stimulus#GO:0071466;monocarboxylic acid catabolic process#GO:0072329;response to chemical#GO:0042221;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;xenobiotic metabolic process#GO:0006805;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;oxoacid metabolic process#GO:0043436			
ECOLI|EnsemblGenome=b1779|UniProtKB=P0A9B2	P0A9B2	gapA	PTHR10836:SF76	GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE	GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE-RELATED	glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903	organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;carbohydrate metabolic process#GO:0005975;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide catabolic process#GO:0009166;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;oxoacid metabolic process#GO:0043436;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;ADP catabolic process#GO:0046032;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	dehydrogenase#PC00092	Huntington disease#P00029>GAPDH#P00810;Glycolysis#P00024>Glyceraldehyde 3-phosphate dehydrogenase#P00676
ECOLI|EnsemblGenome=b3930|UniProtKB=P32166	P32166	menA	PTHR13929:SF18	1,4-DIHYDROXY-2-NAPHTHOATE OCTAPRENYLTRANSFERASE	1,4-DIHYDROXY-2-NAPHTHOATE OCTAPRENYLTRANSFERASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765	ketone metabolic process#GO:0042180;vitamin K metabolic process#GO:0042373;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;small molecule metabolic process#GO:0044281;menaquinone biosynthetic process#GO:0009234;biosynthetic process#GO:0009058;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transferase#PC00220	
ECOLI|EnsemblGenome=b1015|UniProtKB=P07117	P07117	putP	PTHR48086:SF3	SODIUM/PROLINE SYMPORTER-RELATED	SODIUM_PROLINE SYMPORTER	monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943;active transmembrane transporter activity#GO:0022804;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857	transport#GO:0006810;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;organic acid transport#GO:0015849;neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	primary active transporter#PC00068	
ECOLI|EnsemblGenome=b3262|UniProtKB=P28638	P28638	yhdJ	PTHR13370:SF33	RNA METHYLASE-RELATED	DNA ADENINE METHYLTRANSFERASE YHDJ	catalytic activity, acting on DNA#GO:0140097;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757		cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	RNA methyltransferase#PC00033;RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b0972|UniProtKB=P69739	P69739	hyaA	PTHR30013:SF6	NIFE / NIFESE HYDROGENASE SMALL SUBUNIT FAMILY MEMBER	HYDROGENASE-1 SMALL CHAIN		cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;anaerobic respiration#GO:0009061;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980	cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;membrane#GO:0016020	metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0334|UniProtKB=P77243	P77243	prpD	PTHR16943:SF17	2-METHYLCITRATE DEHYDRATASE-RELATED	2-METHYLCITRATE DEHYDRATASE		lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281		dehydratase#PC00091;lyase#PC00144;metabolite interconversion enzyme#PC00262	Methylcitrate cycle#P02754>2-Methylcitrate dehydratase#P03031
ECOLI|EnsemblGenome=b0914|UniProtKB=P60752	P60752	msbA	PTHR24221:SF672	ATP-BINDING CASSETTE SUB-FAMILY B	ATP-DEPENDENT LIPID A-CORE FLIPPASE	active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626	cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234		ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b3772|UniProtKB=P04968	P04968	ilvA	PTHR48078:SF11	THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED	THREONINE DEHYDRATASE, MITOCHONDRIAL	catalytic activity#GO:0003824;lyase activity#GO:0016829	amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;aspartate family amino acid biosynthetic process#GO:0009067;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;branched-chain amino acid biosynthetic process#GO:0009082;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436		lyase#PC00144;dehydratase#PC00091	Isoleucine biosynthesis#P02748>Threonine dehydratase#P02995
ECOLI|EnsemblGenome=b2518|UniProtKB=P0A763	P0A763	ndk	PTHR11349:SF91	NUCLEOSIDE DIPHOSPHATE KINASE	NUCLEOSIDE DIPHOSPHATE KINASE	nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776	biosynthetic process#GO:0009058;nucleoside triphosphate metabolic process#GO:0009141;metabolic process#GO:0008152;phosphorus metabolic process#GO:0006793;nucleoside triphosphate biosynthetic process#GO:0009142;cellular process#GO:0009987	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	transferase#PC00220;kinase#PC00137	De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919
ECOLI|EnsemblGenome=b4335|UniProtKB=P39384	P39384	yjiM	PTHR30548:SF6	2-HYDROXYGLUTARYL-COA DEHYDRATASE, D-COMPONENT-RELATED	DEHYDRATASE SUBUNIT YJIM-RELATED				dehydratase#PC00091;lyase#PC00144	
ECOLI|EnsemblGenome=b3166|UniProtKB=P60340	P60340	truB	PTHR13767:SF3	TRNA-PSEUDOURIDINE SYNTHASE	TRNA PSEUDOURIDINE SYNTHASE B	catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853	pseudouridine synthesis#GO:0001522;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA modification#GO:0016556;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170		isomerase#PC00135;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3564|UniProtKB=P09099	P09099	xylB	PTHR43095:SF6	SUGAR KINASE	XYLULOSE KINASE	transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824			carbohydrate kinase#PC00065	Ascorbate degradation#P02729>L-xylulose kinase#P02849
ECOLI|EnsemblGenome=b2483|UniProtKB=P77858	P77858	hyfC	PTHR43359:SF1	FORMATE HYDROGENLYASE SUBUNIT 4	FORMATE HYDROGENLYASE SUBUNIT 4-RELATED		generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;anaerobic electron transport chain#GO:0019645;anaerobic respiration#GO:0009061	oxidoreductase complex#GO:1990204;membrane#GO:0016020;cell periphery#GO:0071944;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886	metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1398|UniProtKB=P76085	P76085	paaK	PTHR43439:SF1	PHENYLACETATE-COENZYME A LIGASE	PHENYLACETATE-COENZYME A LIGASE	ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874	cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;response to xenobiotic stimulus#GO:0009410;xenobiotic metabolic process#GO:0006805;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987		ligase#PC00142	
ECOLI|EnsemblGenome=b3086|UniProtKB=P42598	P42598	ygjQ	PTHR30336:SF6	INNER MEMBRANE PROTEIN, PROBABLE PERMEASE	INTEGRAL MEMBRANE PROTEIN			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b3965|UniProtKB=P23003	P23003	trmA	PTHR47790:SF2	TRNA/TMRNA (URACIL-C(5))-METHYLTRANSFERASE	TRNA_TMRNA (URACIL-C(5))-METHYLTRANSFERASE	RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;rRNA binding#GO:0019843;catalytic activity#GO:0003824;transferase activity#GO:0016740;tRNA binding#GO:0000049;catalytic activity, acting on a tRNA#GO:0140101;RNA binding#GO:0003723;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;nucleic acid binding#GO:0003676;binding#GO:0005488		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	RNA processing factor#PC00147;RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b0571|UniProtKB=P0ACZ8	P0ACZ8	cusR	PTHR48111:SF41	REGULATOR OF RPOS	TRANSCRIPTIONAL REGULATORY PROTEIN CUSR-RELATED	nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;molecular transducer activity#GO:0060089;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b1314|UniProtKB=P76044	P76044	ycjR	PTHR43489:SF7	ISOMERASE	3-DEHYDRO-D-GULOSIDE 4-EPIMERASE				isomerase#PC00135;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2125|UniProtKB=P0AFT5	P0AFT5	btsR	PTHR48111:SF3	REGULATOR OF RPOS	TRANSCRIPTIONAL REGULATORY PROTEIN BTSR	transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993	helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b2835|UniProtKB=P39196	P39196	lplT	PTHR43266:SF2	MACROLIDE-EFFLUX PROTEIN	LYSOPHOSPHOLIPID TRANSPORTER LPLT		transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;biological regulation#GO:0065007;membrane organization#GO:0061024;lipid localization#GO:0010876;localization#GO:0051179;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1301|UniProtKB=P37906	P37906	puuB	PTHR13847:SF275	SARCOSINE DEHYDROGENASE-RELATED	GAMMA-GLUTAMYLPUTRESCINE OXIDOREDUCTASE			cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b4072|UniProtKB=P0AAK7	P0AAK7	nrfC	PTHR43177:SF9	PROTEIN NRFC	PROTEIN NRFC	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0429|UniProtKB=P0ABJ6	P0ABJ6	cyoD	PTHR36835:SF1	CYTOCHROME BO(3) UBIQUINOL OXIDASE SUBUNIT 4	CYTOCHROME BO(3) UBIQUINOL OXIDASE SUBUNIT 4	electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804	transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;establishment of localization#GO:0051234;energy derivation by oxidation of organic compounds#GO:0015980;proton transmembrane transport#GO:1902600;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;aerobic electron transport chain#GO:0019646;monoatomic ion transport#GO:0006811;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;transmembrane transport#GO:0055085;oxidative phosphorylation#GO:0006119;localization#GO:0051179;monoatomic cation transport#GO:0006812	catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;respiratory chain complex#GO:0098803;cytochrome complex#GO:0070069;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165	oxidase#PC00175;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3657|UniProtKB=P31435	P31435	yicJ	PTHR11328:SF52	MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN	INNER MEMBRANE SYMPORTER YICJ-RELATED		transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	primary active transporter#PC00068	
ECOLI|EnsemblGenome=b1390|UniProtKB=P76079	P76079	paaC	PTHR30458:SF0	PHENYLACETIC ACID DEGRADATION PROTEIN PAA	1,2-PHENYLACETYL-COA EPOXIDASE, SUBUNIT C		oxoacid metabolic process#GO:0043436;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;cellular response to stimulus#GO:0051716;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;xenobiotic metabolic process#GO:0006805;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;response to stimulus#GO:0050896;metabolic process#GO:0008152;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;cellular response to xenobiotic stimulus#GO:0071466;monocarboxylic acid catabolic process#GO:0072329;response to chemical#GO:0042221	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3665|UniProtKB=P31441	P31441	ade	PTHR11113:SF2	N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE	ADENINE DEAMINASE	catalytic activity#GO:0003824;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810			metabolite interconversion enzyme#PC00262;deacetylase#PC00087	
ECOLI|EnsemblGenome=b1659|UniProtKB=P0ACR2	P0ACR2	punR	PTHR30126:SF18	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR PUNR	double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090		gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b2342|UniProtKB=P76503	P76503	fadI	PTHR18919:SF177	ACETYL-COA C-ACYLTRANSFERASE	3-KETOACYL-COA THIOLASE FADI	acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	transferase#PC00220;acyltransferase#PC00042	
ECOLI|EnsemblGenome=b0873|UniProtKB=P75825	P75825	hcp	PTHR30109:SF0	HYDROXYLAMINE REDUCTASE	HYDROXYLAMINE REDUCTASE	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601	metabolic process#GO:0008152;response to oxygen-containing compound#GO:1901700;response to oxidative stress#GO:0006979;response to reactive oxygen species#GO:0000302;response to stress#GO:0006950;cellular process#GO:0009987;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to chemical#GO:0042221		oxidoreductase#PC00176;reductase#PC00198	
ECOLI|EnsemblGenome=b1593|UniProtKB=P0A6E9	P0A6E9	bioD2	PTHR43210:SF4	DETHIOBIOTIN SYNTHETASE	ATP-DEPENDENT DETHIOBIOTIN SYNTHETASE BIOD 2	catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879	small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;biotin metabolic process#GO:0006768;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b3962|UniProtKB=P27306	P27306	sthA	PTHR22912:SF93	DISULFIDE OXIDOREDUCTASE	SOLUBLE PYRIDINE NUCLEOTIDE TRANSHYDROGENASE	nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491	small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2556|UniProtKB=P52101	P52101	glrK	PTHR42878:SF7	TWO-COMPONENT HISTIDINE KINASE	SENSOR HISTIDINE KINASE GLRK	phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;protein histidine kinase activity#GO:0004673;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772	signaling#GO:0023052;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;osmosensory signaling pathway#GO:0007231;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;phosphorelay signal transduction system#GO:0000160;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stress#GO:0033554;cellular response to osmotic stress#GO:0071470;cellular response to chemical stimulus#GO:0070887;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;cellular response to abiotic stimulus#GO:0071214;cellular response to chemical stress#GO:0062197;response to osmotic stress#GO:0006970		transmembrane signal receptor#PC00197;histidine kinase receptor of two-component system#PC00265	
ECOLI|EnsemblGenome=b3562|UniProtKB=P0ADJ8	P0ADJ8	yiaA	PTHR37290:SF1	INNER MEMBRANE PROTEIN YIAA-RELATED	INNER MEMBRANE PROTEIN YIAA		response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b2341|UniProtKB=P77399	P77399	fadJ	PTHR43612:SF8	TRIFUNCTIONAL ENZYME SUBUNIT ALPHA	FATTY ACID OXIDATION COMPLEX SUBUNIT ALPHA					
ECOLI|EnsemblGenome=b4354|UniProtKB=P39396	P39396	btsT	PTHR30252:SF3	INNER MEMBRANE PEPTIDE TRANSPORTER	PYRUVATE_PROTON SYMPORTER BTST	secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;monocarboxylic acid transmembrane transporter activity#GO:0008028	carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;cellular response to nutrient levels#GO:0031669;monocarboxylic acid transport#GO:0015718;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to nutrient levels#GO:0031667;carboxylic acid transmembrane transport#GO:1905039;response to stimulus#GO:0050896	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b1695|UniProtKB=P0A9U8	P0A9U8	ydiO	PTHR48083:SF2	MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED	COMPLEX I ASSEMBLY FACTOR EGM, MITOCHONDRIAL	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824	cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;lipid modification#GO:0030258;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b3318|UniProtKB=P0ADZ0	P0ADZ0	rplW	PTHR11620:SF2	60S RIBOSOMAL PROTEIN L23A	LARGE RIBOSOMAL SUBUNIT PROTEIN UL23	structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735		membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840	ribosomal protein#PC00202;translational protein#PC00263	
ECOLI|EnsemblGenome=b2430|UniProtKB=P77619	P77619	yfeW	PTHR43283:SF11	BETA-LACTAMASE-RELATED	D-ALANYL-D-ALANINE CARBOXYPEPTIDASE-RELATED	carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824			metabolite interconversion enzyme#PC00262;hydrolase#PC00121	
ECOLI|EnsemblGenome=b1667|UniProtKB=P0ACX3	P0ACX3	ydhR	PTHR39169:SF1	FAMILY NOT NAMED	MONOOXYGENASE YDHR-RELATED					
ECOLI|EnsemblGenome=b2057|UniProtKB=P71237	P71237	wcaC	PTHR12526:SF632	GLYCOSYLTRANSFERASE	COLANIC ACID BIOSYNTHESIS GLYCOSYL TRANSFERASE WCAC-RELATED				glycosyltransferase#PC00111;transferase#PC00220	
ECOLI|EnsemblGenome=b3485|UniProtKB=P0AGH1	P0AGH1	yhhJ	PTHR30294:SF49	MEMBRANE COMPONENT OF ABC TRANSPORTER YHHJ-RELATED	INNER MEMBRANE TRANSPORT PERMEASE YHHJ			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0329|UniProtKB=P75694	P75694	yahO	PTHR34156:SF8	OUTER MEMBRANE PROTEIN-RELATED-RELATED	PERIPLASMIC PROTEIN		response to stress#GO:0006950;response to stimulus#GO:0050896			
ECOLI|EnsemblGenome=b3290|UniProtKB=P0AGI8	P0AGI8	trkA	PTHR43833:SF5	POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED	TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKA	channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803	monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	ion channel#PC00133;transporter#PC00227	
ECOLI|EnsemblGenome=b3949|UniProtKB=P32672	P32672	frwC	PTHR30505:SF34	FRUCTOSE-LIKE PERMEASE	FRUCTOSE-LIKE PERMEASE IIC COMPONENT 2	protein-phosphocysteine-sugar phosphotransferase activity#GO:0090563;carbohydrate transmembrane transporter activity#GO:0015144;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;active transmembrane transporter activity#GO:0022804	cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739;transport#GO:0006810;carbohydrate transport#GO:0008643;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b4396|UniProtKB=P0ACI0	P0ACI0	rob	PTHR47504:SF5	RIGHT ORIGIN-BINDING PROTEIN	RIGHT ORIGIN-BINDING PROTEIN	protein binding#GO:0005515;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899	regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119	
ECOLI|EnsemblGenome=b3811|UniProtKB=P0A8P6	P0A8P6	xerC	PTHR30349:SF64	PHAGE INTEGRASE-RELATED	TYROSINE RECOMBINASE XERC	catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640	chromosome segregation#GO:0007059;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139		viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b4218|UniProtKB=P0AE45	P0AE45	paeA	PTHR22777:SF16	HEMOLYSIN-RELATED	POLYAMINE EXPORT PROTEIN			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b4202|UniProtKB=P0A7T7	P0A7T7	rpsR	PTHR13479:SF67	30S RIBOSOMAL PROTEIN S18	SMALL RIBOSOMAL SUBUNIT PROTEIN BS18	structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198			translational protein#PC00263;ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b3162|UniProtKB=P0A9P6	P0A9P6	deaD	PTHR47963:SF8	DEAD-BOX ATP-DEPENDENT RNA HELICASE 47, MITOCHONDRIAL	ATP-DEPENDENT RNA HELICASE DEAD	RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded RNA binding#GO:0003727;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824	response to cold#GO:0009409;response to stimulus#GO:0050896;response to temperature stimulus#GO:0009266;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628	intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232	RNA metabolism protein#PC00031;RNA helicase#PC00032	
ECOLI|EnsemblGenome=b1831|UniProtKB=P45577	P45577	proQ	PTHR38106:SF1	RNA CHAPERONE PROQ	RNA CHAPERONE PROQ	double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;single-stranded RNA binding#GO:0003727	regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b2262|UniProtKB=P0ABU0	P0ABU0	menB	PTHR43113:SF3	NUCLEOSIDE-DIPHOSPHATE-SUGAR EPIMERASE	1,4-DIHYDROXY-2-NAPHTHOYL-COA SYNTHASE	lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824	small molecule metabolic process#GO:0044281;menaquinone biosynthetic process#GO:0009234;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	epimerase/racemase#PC00096	
ECOLI|EnsemblGenome=b0940|UniProtKB=P75857	P75857	elfC	PTHR30451:SF21	OUTER MEMBRANE USHER PROTEIN	FIMBRIAL USHER DOMAIN-CONTAINING PROTEIN YDET-RELATED	passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;channel activity#GO:0015267	cell adhesion#GO:0007155;cellular process#GO:0009987	cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane#GO:0019867;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;membrane#GO:0016020;cell outer membrane#GO:0009279		
ECOLI|EnsemblGenome=b1737|UniProtKB=P17334	P17334	chbC	PTHR33989:SF4	FAMILY NOT NAMED	PTS SYSTEM N,N'-DIACETYLCHITOBIOSE-SPECIFIC EIIC COMPONENT					
ECOLI|EnsemblGenome=b3168|UniProtKB=P0A705	P0A705	infB	PTHR43381:SF22	TRANSLATION INITIATION FACTOR IF-2-RELATED	TRANSLATION INITIATION FACTOR IF-2	translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051	macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	translation initiation factor#PC00224	
ECOLI|EnsemblGenome=b1800|UniProtKB=P76251	P76251	dmlA	PTHR43275:SF1	D-MALATE DEHYDROGENASE [DECARBOXYLATING]	D-MALATE DEHYDROGENASE [DECARBOXYLATING]	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616			oxidoreductase#PC00176;dehydrogenase#PC00092	Leucine biosynthesis#P02749>3-Isopropylmalate dehydrogenase#P03001
ECOLI|EnsemblGenome=b0851|UniProtKB=P17117	P17117	nfsA	PTHR43425:SF4	OXYGEN-INSENSITIVE NADPH NITROREDUCTASE	OXYGEN-INSENSITIVE NADPH NITROREDUCTASE	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;oxidoreductase activity, acting on NAD(P)H#GO:0016651;NAD(P)H dehydrogenase (quinone) activity#GO:0003955;catalytic activity#GO:0003824		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176;peroxidase#PC00180;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3684|UniProtKB=P31453	P31453	yidP	PTHR44846:SF1	MANNOSYL-D-GLYCERATE TRANSPORT/METABOLISM SYSTEM REPRESSOR MNGR-RELATED	HTH-TYPE TRANSCRIPTIONAL REGULATOR GGAR-RELATED		negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355		DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b3031|UniProtKB=P0A8Z7	P0A8Z7	yqiA	PTHR35602:SF3	ESTERASE YQIA-RELATED	ESTERASE YQIA				hydrolase#PC00121;esterase#PC00097;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0045|UniProtKB=P31679	P31679	yaaU	PTHR23511:SF14	SYNAPTIC VESICLE GLYCOPROTEIN 2	METABOLITE TRANSPORT PROTEIN YAAU-RELATED			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b0726|UniProtKB=P0AFG3	P0AFG3	sucA	PTHR23152:SF39	2-OXOGLUTARATE DEHYDROGENASE	2-OXOGLUTARATE DEHYDROGENASE E1 COMPONENT				oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	TCA cycle#P00051>alphaketoglutarate Dehydrogenase#P01269
ECOLI|EnsemblGenome=b1938|UniProtKB=P25798	P25798	fliF	PTHR30046:SF0	FLAGELLAR M-RING PROTEIN	FLAGELLAR M-RING PROTEIN				structural protein#PC00211	
ECOLI|EnsemblGenome=b4170|UniProtKB=P23367	P23367	mutL	PTHR10073:SF56	DNA MISMATCH REPAIR PROTEIN  MLH, PMS, MUTL	DNA MISMATCH REPAIR PROTEIN MUTL	ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111	response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;mismatch repair#GO:0006298;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554	intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b1330|UniProtKB=P0AEB5	P0AEB5	ynaI	PTHR43634:SF2	OW CONDUCTANCE MECHANOSENSITIVE CHANNEL	LOW CONDUCTANCE MECHANOSENSITIVE CHANNEL YNAI	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216	response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to environmental stimulus#GO:0104004;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to osmotic stress#GO:0071470;cellular response to chemical stimulus#GO:0070887;response to osmotic stress#GO:0006970;cellular response to stress#GO:0033554;cellular response to abiotic stimulus#GO:0071214;cellular response to chemical stress#GO:0062197		ion channel#PC00133	
ECOLI|EnsemblGenome=b2314|UniProtKB=P09549	P09549	dedD	PTHR38687:SF1	CELL DIVISION PROTEIN DEDD-RELATED	CELL DIVISION PROTEIN DEDD		cytokinesis#GO:0000910;cytokinetic process#GO:0032506;cellular component organization or biogenesis#GO:0071840;division septum assembly#GO:0000917;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cell cycle#GO:0007049;cell septum assembly#GO:0090529;cellular process#GO:0009987;cell cycle process#GO:0022402;cell division#GO:0051301;cellular component assembly#GO:0022607	cell division site#GO:0032153;division septum#GO:0000935;cell septum#GO:0030428;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1203|UniProtKB=P0ABU2	P0ABU2	ychF	PTHR23305:SF18	OBG GTPASE FAMILY	OBG-LIKE ATPASE HOMOLOG	catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887		cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	G-protein#PC00020	
ECOLI|EnsemblGenome=b0821|UniProtKB=P75791	P75791	ybiU	PTHR30613:SF1	UNCHARACTERIZED PROTEIN YBIU-RELATED	DUF1479 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G09280)					
ECOLI|EnsemblGenome=b0073|UniProtKB=P30125	P30125	leuB	PTHR42979:SF1	3-ISOPROPYLMALATE DEHYDROGENASE	3-ISOPROPYLMALATE DEHYDROGENASE	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616	carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;branched-chain amino acid biosynthetic process#GO:0009082;proteinogenic amino acid biosynthetic process#GO:0170038	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	dehydrogenase#PC00092	Leucine biosynthesis#P02749>3-Isopropylmalate dehydrogenase#P03001
ECOLI|EnsemblGenome=b2335|UniProtKB=P76501	P76501	yfcR	PTHR33420:SF34	FIMBRIAL SUBUNIT ELFA-RELATED	MINOR FIMBRIAL SUBUNIT		cellular process#GO:0009987;cell adhesion#GO:0007155;single-species biofilm formation#GO:0044010;cell-substrate adhesion#GO:0031589	cellular anatomical structure#GO:0110165;cell projection#GO:0042995		
ECOLI|EnsemblGenome=b2519|UniProtKB=P76577	P76577	pbpC	PTHR32282:SF15	BINDING PROTEIN TRANSPEPTIDASE, PUTATIVE-RELATED	PENICILLIN-BINDING PROTEIN 1C	hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757	cellular component biogenesis#GO:0044085;cell wall macromolecule biosynthetic process#GO:0044038;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cell wall organization or biogenesis#GO:0071554;biosynthetic process#GO:0009058;peptidoglycan metabolic process#GO:0000270;metabolic process#GO:0008152;peptidoglycan-based cell wall biogenesis#GO:0009273;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;glycosaminoglycan biosynthetic process#GO:0006024;carbohydrate derivative biosynthetic process#GO:1901137;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan metabolic process#GO:0030203;peptidoglycan biosynthetic process#GO:0009252;aminoglycan metabolic process#GO:0006022;cell wall biogenesis#GO:0042546;cell wall macromolecule metabolic process#GO:0044036	cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;extracellular region#GO:0005576;periplasmic space#GO:0042597		
ECOLI|EnsemblGenome=b0053|UniProtKB=P0ABZ6	P0ABZ6	surA	PTHR47637:SF1	CHAPERONE SURA	CHAPERONE SURA	catalytic activity, acting on a protein#GO:0140096;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859;catalytic activity#GO:0003824	protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059	periplasmic space#GO:0042597;extracellular region#GO:0005576;cell envelope#GO:0030313;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165	chaperone#PC00072	
ECOLI|EnsemblGenome=b2804|UniProtKB=P0AEN8	P0AEN8	fucU	PTHR31690:SF4	FUCOSE MUTAROTASE	FUCOSE MUTAROTASE	binding#GO:0005488;small molecule binding#GO:0036094;carbohydrate binding#GO:0030246;monosaccharide binding#GO:0048029;isomerase activity#GO:0016853;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857	small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;hexose metabolic process#GO:0019318;monosaccharide metabolic process#GO:0005996;primary metabolic process#GO:0044238;cellular process#GO:0009987			
ECOLI|EnsemblGenome=b4178|UniProtKB=P0AF63	P0AF63	nsrR	PTHR33221:SF4	WINGED HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, RRF2 FAMILY	HTH-TYPE TRANSCRIPTIONAL REPRESSOR NSRR	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b2172|UniProtKB=P33029	P33029	yeiQ	PTHR43362:SF1	MANNITOL DEHYDROGENASE DSF1-RELATED	D-MANNONATE OXIDOREDUCTASE	oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824			oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2023|UniProtKB=P60595	P60595	hisH	PTHR42701:SF1	IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISH	IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISH	glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763	oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;aromatic amino acid biosynthetic process#GO:0009073;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;transferase complex#GO:1990234		Histidine biosynthesis#P02747>Imidazol glycerol phosphate synthase#P02992
ECOLI|EnsemblGenome=b0010|UniProtKB=P0AC98	P0AC98	satP	PTHR30178:SF3	INNER MEMBRANE PROTEIN YAAH	SUCCINATE-ACETATE_PROTON SYMPORTER SATP				primary active transporter#PC00068;transporter#PC00227	
ECOLI|EnsemblGenome=b3887|UniProtKB=P0A6M4	P0A6M4	dtd	PTHR10472:SF5	D-TYROSYL-TRNA TYR  DEACYLASE	D-AMINOACYL-TRNA DEACYLASE 1	catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;deacylase activity#GO:0160215;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101;carboxylic ester hydrolase activity#GO:0052689	RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097	
ECOLI|EnsemblGenome=b1322|UniProtKB=P0A8R7	P0A8R7	ycjF	PTHR39342:SF1	UPF0283 MEMBRANE PROTEIN YCJF	UPF0283 MEMBRANE PROTEIN YCJF			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2193|UniProtKB=P31802	P31802	narP	PTHR43214:SF43	TWO-COMPONENT RESPONSE REGULATOR	NITRATE_NITRITE RESPONSE REGULATOR PROTEIN NARP	DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889		helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b1422|UniProtKB=P77171	P77171	ydcI	PTHR30419:SF8	HTH-TYPE TRANSCRIPTIONAL REGULATOR YBHD	HTH-TYPE TRANSCRIPTIONAL REGULATOR YDCI	DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488	regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b4043|UniProtKB=P0A7C2	P0A7C2	lexA	PTHR33516:SF2	LEXA REPRESSOR	LEXA REPRESSOR-RELATED	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA-binding transcription repressor activity#GO:0001217;DNA binding#GO:0003677	negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;cellular response to stress#GO:0033554;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;SOS response#GO:0009432;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;DNA damage response#GO:0006974;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468	protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991	DNA-binding transcription factor#PC00218;Lambda repressor-like transcription factor#PC00245;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b1284|UniProtKB=P76034	P76034	yciT	PTHR30363:SF44	HTH-TYPE TRANSCRIPTIONAL REGULATOR SRLR-RELATED	HTH DEOR-TYPE DOMAIN-CONTAINING PROTEIN	double-stranded DNA binding#GO:0003690;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252		helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b3784|UniProtKB=P0AC78	P0AC78	wecA	PTHR22926:SF3	PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE	UNDECAPRENYL-PHOSPHATE ALPHA-N-ACETYLGLUCOSAMINYL 1-PHOSPHATE TRANSFERASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780	carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell wall macromolecule biosynthetic process#GO:0044038;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;cell wall organization or biogenesis#GO:0071554;cell wall organization#GO:0071555;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;lipopolysaccharide biosynthetic process#GO:0009103;liposaccharide metabolic process#GO:1903509;polysaccharide metabolic process#GO:0005976;polysaccharide biosynthetic process#GO:0000271;external encapsulating structure organization#GO:0045229;cell wall macromolecule metabolic process#GO:0044036;cell wall biogenesis#GO:0042546;lipopolysaccharide metabolic process#GO:0008653	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	glycosyltransferase#PC00111;transferase#PC00220	
ECOLI|EnsemblGenome=b0344|UniProtKB=P00722	P00722	lacZ	PTHR46323:SF2	BETA-GALACTOSIDASE	BETA-GALACTOSIDASE	hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553	cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;oligosaccharide catabolic process#GO:0009313;catabolic process#GO:0009056;metabolic process#GO:0008152;oligosaccharide metabolic process#GO:0009311;carbohydrate catabolic process#GO:0016052	catalytic complex#GO:1902494;protein-containing complex#GO:0032991	metabolite interconversion enzyme#PC00262;hydrolase#PC00121;galactosidase#PC00104	
ECOLI|EnsemblGenome=b2406|UniProtKB=P45562	P45562	xapB	PTHR23522:SF9	BLL5896 PROTEIN	XANTHOSINE PERMEASE	carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleoside transmembrane transporter activity#GO:0005337;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b3667|UniProtKB=P09836	P09836	uhpC	PTHR43826:SF12	GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4	MEMBRANE SENSOR PROTEIN UHPC	phosphate transmembrane transporter activity#GO:0005315;organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;antiporter activity#GO:0015297;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804	transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;inorganic anion transport#GO:0015698;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;organophosphate ester transport#GO:0015748;phosphate ion transport#GO:0006817		primary active transporter#PC00068	
ECOLI|EnsemblGenome=b2296|UniProtKB=P0A6A3	P0A6A3	ackA	PTHR21060:SF21	ACETATE KINASE	ACETATE KINASE	phosphotransferase activity, carboxyl group as acceptor#GO:0016774;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301	oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;small molecule metabolic process#GO:0044281	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	kinase#PC00137;transferase#PC00220	Acetate utilization#P02722>Acetate kinase#P02801
ECOLI|EnsemblGenome=b4127|UniProtKB=P39274	P39274	yjdJ	PTHR31435:SF10	PROTEIN NATD1	N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN					
ECOLI|EnsemblGenome=b2436|UniProtKB=P36553	P36553	hemF	PTHR10755:SF0	COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL	OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL	catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491	metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148;porphyrin-containing compound biosynthetic process#GO:0006779;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;cellular process#GO:0009987;tetrapyrrole biosynthetic process#GO:0033014;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	metabolite interconversion enzyme#PC00262;oxidase#PC00175;oxidoreductase#PC00176	Heme biosynthesis#P02746>Coproporphyrinogen Oxidase (oxygen dependent)#P02980
ECOLI|EnsemblGenome=b0757|UniProtKB=P0A6T3	P0A6T3	galK	PTHR10457:SF7	MEVALONATE KINASE/GALACTOKINASE	GALACTOKINASE-RELATED	phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200	carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;metabolic process#GO:0008152	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	carbohydrate kinase#PC00065;metabolite interconversion enzyme#PC00262;kinase#PC00137;transferase#PC00220	Fructose galactose metabolism#P02744>Galactokinase#P02960
ECOLI|EnsemblGenome=b2258|UniProtKB=P76474	P76474	arnF	PTHR30561:SF9	SMR FAMILY PROTON-DEPENDENT DRUG EFFLUX TRANSPORTER SUGE	4-AMINO-4-DEOXY-L-ARABINOSE-PHOSPHOUNDECAPRENOL FLIPPASE SUBUNIT ARNF-RELATED	carbohydrate derivative transmembrane transporter activity#GO:1901505;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	transport#GO:0006810;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b1608|UniProtKB=P52108	P52108	rstA	PTHR48111:SF47	REGULATOR OF RPOS	TRANSCRIPTIONAL REGULATORY PROTEIN RSTA	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;molecular transducer activity#GO:0060089;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690	regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991	helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b1465|UniProtKB=P0AF32	P0AF32	narV	PTHR30598:SF4	NITRATE REDUCTASE PRIVATE CHAPERONE, REDOX ENZYME MATURATION PROTEIN  REMP  FAMILY	RESPIRATORY NITRATE REDUCTASE 2 GAMMA CHAIN	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;nitrate metabolic process#GO:0042126;electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;small molecule metabolic process#GO:0044281;anaerobic respiration#GO:0009061;anaerobic electron transport chain#GO:0019645	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;membrane#GO:0016020	chaperone#PC00072	
ECOLI|EnsemblGenome=b4226|UniProtKB=P0A7A9	P0A7A9	ppa	PTHR10286:SF89	INORGANIC PYROPHOSPHATASE	INORGANIC PYROPHOSPHATASE	cation binding#GO:0043169;magnesium ion binding#GO:0000287;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;ion binding#GO:0043167;small molecule binding#GO:0036094;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824	phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;metabolic process#GO:0008152	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	pyrophosphatase#PC00196	
ECOLI|EnsemblGenome=b3500|UniProtKB=P06715	P06715	gor	PTHR42737:SF11	GLUTATHIONE REDUCTASE	GLUTATHIONE REDUCTASE	nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;flavin adenine dinucleotide binding#GO:0050660;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;disulfide oxidoreductase activity#GO:0015036;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491	modified amino acid metabolic process#GO:0006575;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;homeostatic process#GO:0042592;glutathione metabolic process#GO:0006749;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to stress#GO:0006950;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;metabolic process#GO:0008152;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	reductase#PC00198;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0487|UniProtKB=P0A9G4	P0A9G4	cueR	PTHR30204:SF16	REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR	HTH-TYPE TRANSCRIPTIONAL REGULATOR CUER	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518		helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b2422|UniProtKB=P16676	P16676	cysA	PTHR43514:SF1	ABC TRANSPORTER I FAMILY MEMBER 10	SULFATE_THIOSULFATE IMPORT ATP-BINDING PROTEIN CYSA		cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;inorganic anion transport#GO:0015698		transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0964|UniProtKB=P0A8X4	P0A8X4	yccT	PTHR38108:SF1	UPF0319 PROTEIN YCCT	UPF0319 PROTEIN YCCT			extracellular region#GO:0005576;periplasmic space#GO:0042597;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313		
ECOLI|EnsemblGenome=b0938|UniProtKB=P75855	P75855	elfA	PTHR33420:SF3	FIMBRIAL SUBUNIT ELFA-RELATED	FIMBRIAL SUBUNIT ELFA					
ECOLI|EnsemblGenome=b3628|UniProtKB=P27127	P27127	waaB	PTHR12526:SF630	GLYCOSYLTRANSFERASE	LIPOPOLYSACCHARIDE 1,6-GALACTOSYLTRANSFERASE				glycosyltransferase#PC00111;transferase#PC00220	
ECOLI|EnsemblGenome=b0142|UniProtKB=P26281	P26281	folK	PTHR43071:SF1	2-AMINO-4-HYDROXY-6-HYDROXYMETHYLDIHYDROPTERIDINE PYROPHOSPHOKINASE	2-AMINO-4-HYDROXY-6-HYDROXYMETHYLDIHYDROPTERIDINE PYROPHOSPHOKINASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772			kinase#PC00137;metabolite interconversion enzyme#PC00262	Tetrahydrofolate biosynthesis#P02742>5-Hydroxymethyl-7,8-dihydropteridine pyrophosphokinase#P02946
ECOLI|EnsemblGenome=b2075|UniProtKB=P76398	P76398	mdtB	PTHR32063:SF21	SWARMING MOTILITY PROTEIN SWRC-RELATED	MULTIDRUG RESISTANCE PROTEIN MDTB					
ECOLI|EnsemblGenome=b0188|UniProtKB=P52097	P52097	tilS	PTHR43033:SF1	TRNA(ILE)-LYSIDINE SYNTHASE-RELATED	TRNA(ILE)-LYSIDINE SYNTHASE	catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity, forming carbon-nitrogen bonds#GO:0016879	RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble base modification#GO:0002097;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		Salvage pyrimidine ribonucleotides#P02775>Cytosine deaminase#P03155;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCTP deaminase#P02920;Salvage pyrimidine deoxyribonucleotides#P02774>Cytidine deaminase#P03144;Salvage pyrimidine ribonucleotides#P02775>Cytidine deaminase#P03154
ECOLI|EnsemblGenome=b2881|UniProtKB=Q46814	Q46814	xdhD	PTHR11908:SF132	XANTHINE DEHYDROGENASE	ALDEHYDE OXIDASE 1-RELATED	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824			oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1940|UniProtKB=P31068	P31068	fliH	PTHR34982:SF1	YOP PROTEINS TRANSLOCATION PROTEIN L	FLAGELLAR ASSEMBLY PROTEIN FLIH			cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b2215|UniProtKB=P06996	P06996	ompC	PTHR34501:SF1	PROTEIN YDDL-RELATED	OUTER MEMBRANE PORIN C	wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;membrane protein complex#GO:0098796		
ECOLI|EnsemblGenome=b4213|UniProtKB=P08331	P08331	cpdB	PTHR11575:SF6	5'-NUCLEOTIDASE-RELATED	2',3'-CYCLIC-NUCLEOTIDE 2'-PHOSPHODIESTERASE_3'-NUCLEOTIDASE			extracellular region#GO:0005576;periplasmic space#GO:0042597;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313	hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185	
ECOLI|EnsemblGenome=b0680|UniProtKB=P00962	P00962	glnS	PTHR43097:SF4	GLUTAMINE-TRNA LIGASE	GLUTAMINE--TRNA LIGASE	ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101	amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	aminoacyl-tRNA synthetase#PC00047	Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977
ECOLI|EnsemblGenome=b4460|UniProtKB=P0AE26	P0AE26	araH	PTHR32196:SF37	ABC TRANSPORTER PERMEASE PROTEIN YPHD-RELATED-RELATED	L-ARABINOSE TRANSPORT SYSTEM PERMEASE PROTEIN ARAH			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b1633|UniProtKB=P0AB83	P0AB83	nth	PTHR10359:SF18	A/G-SPECIFIC ADENINE GLYCOSYLASE/ENDONUCLEASE III	ENDONUCLEASE III	hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824	macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716			
ECOLI|EnsemblGenome=b3350|UniProtKB=P45522	P45522	kefB	PTHR46157:SF11	K(+) EFFLUX ANTIPORTER 3, CHLOROPLASTIC	GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYSTEM PROTEIN KEFB	monoatomic ion transmembrane transporter activity#GO:0015075;metal cation:proton antiporter activity#GO:0051139;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324	cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;localization#GO:0051179;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b3669|UniProtKB=P0AGA6	P0AGA6	uhpA	PTHR43214:SF22	TWO-COMPONENT RESPONSE REGULATOR	TRANSCRIPTIONAL REGULATORY PROTEIN UHPA	transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252		winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b0488|UniProtKB=P0AAS3	P0AAS3	ybbJ	PTHR33507:SF3	INNER MEMBRANE PROTEIN YBBJ	INNER MEMBRANE PROTEIN YBBJ			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b0493|UniProtKB=P0AFP4	P0AFP4	ybbO	PTHR43313:SF1	SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C	RETINOL DEHYDROGENASE 7	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0261|UniProtKB=Q47690	Q47690	mmuM	PTHR46015:SF1	ZGC:172121	BETAINE-HOMOCYSTEINE S-METHYLTRANSFERASE-RELATED	methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity#GO:0016740;catalytic activity#GO:0003824	small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;aspartate family amino acid biosynthetic process#GO:0009067;proteinogenic amino acid biosynthetic process#GO:0170038;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283			Formyltetrahydrofolate biosynthesis#P02743>Cobalamin dependent homocysteine transmethylase#P02953;Methionine biosynthesis#P02753>Homocysteine transmethylase#P03024
ECOLI|EnsemblGenome=b2819|UniProtKB=P04993	P04993	recD	PTHR43788:SF6	DNA2/NAM7 HELICASE FAMILY MEMBER	RECBCD ENZYME SUBUNIT RECD	ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678	cellular process#GO:0009987;response to stress#GO:0006950;DNA recombination#GO:0006310;negative regulation of double-strand break repair via homologous recombination#GO:2000042;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;negative regulation of metabolic process#GO:0009892;regulation of double-strand break repair via homologous recombination#GO:0010569;response to stimulus#GO:0050896;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of cellular response to stress#GO:0080135;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;regulation of DNA recombination#GO:0000018;negative regulation of DNA metabolic process#GO:0051053;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule metabolic process#GO:0043170;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;negative regulation of DNA recombination#GO:0045910;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of double-strand break repair#GO:2000779	protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b0754|UniProtKB=P0AB91	P0AB91	aroG	PTHR21225:SF12	PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE  DAHP SYNTHETASE	PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, PHE-SENSITIVE	transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824	small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;aromatic amino acid biosynthetic process#GO:0009073;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	lyase#PC00144;aldolase#PC00044	Chorismate biosynthesis#P02734>2-Deoxy-7-phosphoheptulonate synthase#P02871
ECOLI|EnsemblGenome=b3754|UniProtKB=P31474	P31474	hsrA	PTHR23501:SF1	MAJOR FACILITATOR SUPERFAMILY	TRANSPORT PROTEIN HSRA-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b0879|UniProtKB=P75831	P75831	macB	PTHR30572:SF7	MEMBRANE COMPONENT OF TRANSPORTER-RELATED	MACROLIDE EXPORT ATP-BINDING_PERMEASE PROTEIN MACB	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b0068|UniProtKB=P31550	P31550	thiB	PTHR30006:SF3	THIAMINE-BINDING PERIPLASMIC PROTEIN-RELATED	THIAMINE-BINDING PERIPLASMIC PROTEIN					
ECOLI|EnsemblGenome=b2149|UniProtKB=P0AAG8	P0AAG8	mglA	PTHR43790:SF7	CARBOHYDRATE TRANSPORT ATP-BINDING PROTEIN MG119-RELATED	GALACTOSE_METHYL GALACTOSIDE IMPORT ATP-BINDING PROTEIN MGLA	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate derivative transmembrane transporter activity#GO:1901505;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0867|UniProtKB=P75820	P75820	amiD	PTHR30417:SF1	N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMID	N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMID	N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787	aminoglycan metabolic process#GO:0006022;peptidoglycan metabolic process#GO:0000270;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycosaminoglycan metabolic process#GO:0030203;peptidoglycan turnover#GO:0009254		hydrolase#PC00121	
ECOLI|EnsemblGenome=b3839|UniProtKB=P69423	P69423	tatC	PTHR30371:SF0	SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATC	SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATC	secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;transmembrane protein transporter activity#GO:0008320	establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907	plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0086|UniProtKB=P11880	P11880	murF	PTHR43024:SF1	UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE	UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE	ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874	glycosaminoglycan metabolic process#GO:0030203;aminoglycan biosynthetic process#GO:0006023;peptidoglycan biosynthetic process#GO:0009252;aminoglycan metabolic process#GO:0006022;cell wall macromolecule metabolic process#GO:0044036;cell wall biogenesis#GO:0042546;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;cell wall macromolecule biosynthetic process#GO:0044038;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;cell wall organization or biogenesis#GO:0071554;peptidoglycan-based cell wall biogenesis#GO:0009273;metabolic process#GO:0008152;peptidoglycan metabolic process#GO:0000270;carbohydrate derivative biosynthetic process#GO:1901137;glycosaminoglycan biosynthetic process#GO:0006024;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840		ligase#PC00142;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0871|UniProtKB=P07003	P07003	poxB	PTHR42981:SF2	PYRUVATE DEHYDROGENASE [UBIQUINONE]	PYRUVATE DEHYDROGENASE [UBIQUINONE]	oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;metabolic process#GO:0008152;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987		oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	Isoleucine biosynthesis#P02748>Acetolactate synthase#P02997;Valine biosynthesis#P02785>Acetolactate synthase#P03216
ECOLI|EnsemblGenome=b4193|UniProtKB=P39301	P39301	ulaA	PTHR33843:SF4	ASCORBATE-SPECIFIC PTS SYSTEM EIIC COMPONENT	ASCORBATE-SPECIFIC PTS SYSTEM EIIC COMPONENT	protein-phosphocysteine-sugar phosphotransferase activity#GO:0090563;carbohydrate transmembrane transporter activity#GO:0015144;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;active transmembrane transporter activity#GO:0022804	cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;vitamin transport#GO:0051180;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;carbohydrate transport#GO:0008643;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;import into cell#GO:0098657;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179			
ECOLI|EnsemblGenome=b2678|UniProtKB=P14176	P14176	proW	PTHR47737:SF1	GLYCINE BETAINE/PROLINE BETAINE TRANSPORT SYSTEM PERMEASE PROTEIN PROW	GLYCINE BETAINE_PROLINE BETAINE TRANSPORT SYSTEM PERMEASE PROTEIN PROW	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;quaternary ammonium group transmembrane transporter activity#GO:0015651	localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;transport#GO:0006810	transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;ATP-binding cassette (ABC) transporter complex#GO:0043190;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b1115|UniProtKB=P75955	P75955	ycfT	PTHR40074:SF4	O-ACETYLTRANSFERASE WECH	INNER MEMBRANE PROTEIN YCFT	acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407	primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;polysaccharide metabolic process#GO:0005976;carbohydrate biosynthetic process#GO:0016051;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;metabolic process#GO:0008152;polysaccharide biosynthetic process#GO:0000271;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b4471|UniProtKB=P42630	P42630	tdcG	PTHR30182:SF6	L-SERINE DEHYDRATASE	L-SERINE DEHYDRATASE TDCG	lyase activity#GO:0016829;catalytic activity#GO:0003824	small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436		dehydratase#PC00091;lyase#PC00144	
ECOLI|EnsemblGenome=b0544|UniProtKB=P77698	P77698	ybcK	PTHR30461:SF2	DNA-INVERTASE FROM LAMBDOID PROPHAGE	SERINE RECOMBINASE PINE-RELATED	catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824	primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170			
ECOLI|EnsemblGenome=b2044|UniProtKB=P71243	P71243	wcaL	PTHR12526:SF649	GLYCOSYLTRANSFERASE	COLANIC ACID BIOSYNTHESIS GLYCOSYLTRANSFERASE WCAL-RELATED	glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824			glycosyltransferase#PC00111;transferase#PC00220	
ECOLI|EnsemblGenome=b3883|UniProtKB=P32143	P32143	yihV	PTHR10584:SF157	SUGAR KINASE	SULFOFRUCTOSE KINASE	phosphotransferase activity, alcohol group as acceptor#GO:0016773;carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301		cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	kinase#PC00137;carbohydrate kinase#PC00065	
ECOLI|EnsemblGenome=b4321|UniProtKB=P0AC94	P0AC94	gntP	PTHR30354:SF20	GNT FAMILY GLUCONATE TRANSPORTER	HIGH-AFFINITY GLUCONATE TRANSPORTER	monocarboxylic acid transmembrane transporter activity#GO:0008028;carbohydrate transmembrane transporter activity#GO:0015144;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943	cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carboxylic acid transmembrane transport#GO:1905039;carbohydrate transport#GO:0008643;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227;secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b2154|UniProtKB=P33018	P33018	yeiG	PTHR10061:SF1	S-FORMYLGLUTATHIONE HYDROLASE	S-FORMYLGLUTATHIONE HYDROLASE YEIG	hydrolase activity#GO:0016787;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824		cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	protein modifying enzyme#PC00260;serine protease#PC00203	
ECOLI|EnsemblGenome=b0607|UniProtKB=P39177	P39177	uspG	PTHR46268:SF6	STRESS RESPONSE PROTEIN NHAX	UNIVERSAL STRESS PROTEIN UP12					
ECOLI|EnsemblGenome=b1006|UniProtKB=P75892	P75892	rutG	PTHR11119:SF127	XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER	XANTHINE_URACIL PERMEASE FAMILY PROTEIN	symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;nucleobase transmembrane transporter activity#GO:0015205;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804	import across plasma membrane#GO:0098739;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;import into cell#GO:0098657;nucleobase transport#GO:0015851;pyrimidine nucleobase transport#GO:0015855;transport#GO:0006810	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b1244|UniProtKB=P0AFH2	P0AFH2	oppB	PTHR30465:SF74	INNER MEMBRANE ABC TRANSPORTER	OLIGOPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN OPPB	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate derivative transmembrane transporter activity#GO:1901505		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b4045|UniProtKB=P68206	P68206	yjbJ	PTHR34977:SF1	UPF0337 PROTEIN YJBJ	UPF0337 PROTEIN YJBJ					
ECOLI|EnsemblGenome=b2698|UniProtKB=P33596	P33596	recX	PTHR33602:SF2	REGULATORY PROTEIN RECX FAMILY PROTEIN	REGULATORY PROTEIN RECX		DNA damage response#GO:0006974;cellular response to stress#GO:0033554;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;SOS response#GO:0009432;response to stress#GO:0006950;response to stimulus#GO:0050896			
ECOLI|EnsemblGenome=b1310|UniProtKB=P76042	P76042	ycjN	PTHR43649:SF34	ARABINOSE-BINDING PROTEIN-RELATED	MALTOSE-BINDING PROTEIN YCJN-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b2668|UniProtKB=P55734	P55734	ygaP	PTHR44086:SF16	THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED	THIOSULFATE SULFURTRANSFERASE PSPE-RELATED	catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783			transferase#PC00220	
ECOLI|EnsemblGenome=b3664|UniProtKB=P31440	P31440	adeQ	PTHR43337:SF22	XANTHINE/URACIL PERMEASE C887.17-RELATED	ADENINE PERMEASE ADEP-RELATED	nucleobase transmembrane transporter activity#GO:0015205;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b0367|UniProtKB=Q47539	Q47539	tauC	PTHR30151:SF25	ALKANE SULFONATE ABC TRANSPORTER-RELATED, MEMBRANE SUBUNIT	TAURINE TRANSPORT SYSTEM PERMEASE PROTEIN TAUC		cellular response to nutrient levels#GO:0031669;cellular response to stress#GO:0033554;cellular response to starvation#GO:0009267;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to nutrient levels#GO:0031667;response to starvation#GO:0042594;response to stimulus#GO:0050896	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b1673|UniProtKB=P76192	P76192	ydhV	PTHR30038:SF0	ALDEHYDE FERREDOXIN OXIDOREDUCTASE	ALDEHYDE FERREDOXIN OXIDOREDUCTASE YDHV-RELATED				oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3303|UniProtKB=P0A7W1	P0A7W1	rpsE	PTHR13718:SF123	RIBOSOMAL S SUBUNIT	SMALL RIBOSOMAL SUBUNIT PROTEIN US5	structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735	metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058	ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232	ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b3044|UniProtKB=P0CF44	P0CF44	insC5	PTHR37936:SF3	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b3648|UniProtKB=P60546	P60546	gmk	PTHR23117:SF27	GUANYLATE KINASE-RELATED	GUANYLATE KINASE	phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772	nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide biosynthetic process#GO:0006164;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleoside diphosphate metabolic process#GO:0009179;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	transferase#PC00220;kinase#PC00137	De novo purine biosynthesis#P02738>Guanylate kinase#P02904
ECOLI|EnsemblGenome=b4208|UniProtKB=P0AAE0	P0AAE0	cycA	PTHR43495:SF2	GABA PERMEASE	D-SERINE_D-ALANINE_GLYCINE TRANSPORTER	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227;secondary carrier transporter#PC00258;amino acid transporter#PC00046	
ECOLI|EnsemblGenome=b1688|UniProtKB=P0AFS7	P0AFS7	ydiK	PTHR21716:SF67	TRANSMEMBRANE PROTEIN	TRANSPORT PROTEIN YDIK-RELATED		organic hydroxy compound transport#GO:0015850;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b3332|UniProtKB=P45762	P45762	gspK	PTHR38831:SF1	TYPE II SECRETION SYSTEM PROTEIN K	TYPE II SECRETION SYSTEM PROTEIN K-RELATED					
ECOLI|EnsemblGenome=b2282|UniProtKB=P0AFD4	P0AFD4	nuoH	PTHR11432:SF24	NADH DEHYDROGENASE SUBUNIT 1	NADH-QUINONE OXIDOREDUCTASE SUBUNIT H	NADH dehydrogenase activity#GO:0003954;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491	generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980	catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b2584|UniProtKB=P76594	P76594	patZ	PTHR42793:SF1	COA BINDING DOMAIN CONTAINING PROTEIN	PEPTIDYL-LYSINE N-ACETYLTRANSFERASE PATZ	catalytic activity#GO:0003824;transferase activity#GO:0016740;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186				
ECOLI|EnsemblGenome=b3661|UniProtKB=P04846	P04846	nlpA	PTHR30429:SF1	D-METHIONINE-BINDING LIPOPROTEIN METQ	D-METHIONINE-BINDING LIPOPROTEIN METQ-RELATED		localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;import into cell#GO:0098657;amino acid transmembrane transport#GO:0003333;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;transport#GO:0006810;organic acid transport#GO:0015849;import across plasma membrane#GO:0098739;carboxylic acid transmembrane transport#GO:1905039;nitrogen compound transport#GO:0071705;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b3498|UniProtKB=P27298	P27298	prlC	PTHR11804:SF84	PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED	SACCHAROLYSIN	peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824			metalloprotease#PC00153;protease#PC00190	
ECOLI|EnsemblGenome=b4256|UniProtKB=P39337	P39337	yjgM	PTHR13947:SF37	GNAT FAMILY N-ACETYLTRANSFERASE	LD18367P	N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747			acetyltransferase#PC00038	
ECOLI|EnsemblGenome=b2705|UniProtKB=P05707	P05707	srlD	PTHR42760:SF105	SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER	SORBITOL-6-PHOSPHATE 2-DEHYDROGENASE	oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2385|UniProtKB=P76524	P76524	ypdF	PTHR46112:SF3	AMINOPEPTIDASE	AMINOPEPTIDASE YPDF	exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235	primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170		metalloprotease#PC00153	
ECOLI|EnsemblGenome=b1337|UniProtKB=P76052	P76052	abgB	PTHR30575:SF10	PEPTIDASE M20	P-AMINOBENZOYL-GLUTAMATE HYDROLASE SUBUNIT B	catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233	oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	metalloprotease#PC00153	
ECOLI|EnsemblGenome=b0047|UniProtKB=P03819	P03819	kefC	PTHR46157:SF3	K(+) EFFLUX ANTIPORTER 3, CHLOROPLASTIC	GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYSTEM PROTEIN KEFC	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079	monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transport#GO:0006813;cellular process#GO:0009987	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b1035|UniProtKB=P75915	P75915	ycdY	PTHR34227:SF12	CHAPERONE PROTEIN YCDY	CHAPERONE PROTEIN YCDY		metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	chaperone#PC00072	
ECOLI|EnsemblGenome=b3565|UniProtKB=P00944	P00944	xylA	PTHR32176:SF92	XYLOSE ISOMERASE	XYLOSE ISOMERASE				metabolite interconversion enzyme#PC00262;isomerase#PC00135	
ECOLI|EnsemblGenome=b0503|UniProtKB=P33667	P33667	selU	PTHR30401:SF0	TRNA 2-SELENOURIDINE SYNTHASE	TRNA 2-SELENOURIDINE SYNTHASE	catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098	macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059		RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b3807|UniProtKB=P27838	P27838	cyaY	PTHR16821:SF8	FRATAXIN	IRON-SULFUR CLUSTER ASSEMBLY PROTEIN CYAY	binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;ferrous iron binding#GO:0008198;iron ion binding#GO:0005506	cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	transfer/carrier protein#PC00219	
ECOLI|EnsemblGenome=b1075|UniProtKB=P75936	P75936	flgD	PTHR30435:SF15	FLAGELLAR PROTEIN	BASAL-BODY ROD MODIFICATION PROTEIN FLGD		cell motility#GO:0048870;bacterial-type flagellum-dependent cell motility#GO:0071973;bacterial-type flagellum-dependent swarming motility#GO:0071978;archaeal or bacterial-type flagellum-dependent cell motility#GO:0097588;cellular process#GO:0009987;cilium or flagellum-dependent cell motility#GO:0001539	membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;bacterial-type flagellum#GO:0009288;organelle#GO:0043226;cell projection#GO:0042995	structural protein#PC00211	
ECOLI|EnsemblGenome=b0449|UniProtKB=P0AAG5	P0AAG5	mdlB	PTHR24221:SF615	ATP-BINDING CASSETTE SUB-FAMILY B	MULTIDRUG RESISTANCE-LIKE ATP-BINDING PROTEIN MDLB	primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987		ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b3678|UniProtKB=P31447	P31447	yidJ	PTHR42693:SF27	ARYLSULFATASE FAMILY MEMBER	ARYLSULFATASE B	hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788			hydrolase#PC00121	
ECOLI|EnsemblGenome=b1880|UniProtKB=P76299	P76299	flhB	PTHR30531:SF12	FLAGELLAR BIOSYNTHETIC PROTEIN FLHB	FLAGELLAR BIOSYNTHETIC PROTEIN FLHB			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	protease#PC00190;protein modifying enzyme#PC00260	
ECOLI|EnsemblGenome=b3633|UniProtKB=P0AC75	P0AC75	waaA	PTHR42755:SF2	3-DEOXY-MANNO-OCTULOSONATE CYTIDYLYLTRANSFERASE	3-DEOXY-D-MANNO-OCTULOSONIC ACID TRANSFERASE	catalytic activity#GO:0003824;transferase activity#GO:0016740	metabolic process#GO:0008152;lipid metabolic process#GO:0006629;carbohydrate derivative biosynthetic process#GO:1901137;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;lipid A biosynthetic process#GO:0009245;liposaccharide metabolic process#GO:1903509;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;phospholipid metabolic process#GO:0006644	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	metabolite interconversion enzyme#PC00262;transferase#PC00220	
ECOLI|EnsemblGenome=b3800|UniProtKB=P25550	P25550	aslB	PTHR43273:SF3	ANAEROBIC SULFATASE-MATURATING ENZYME HOMOLOG ASLB-RELATED	ANAEROBIC SULFATASE-MATURATING ENZYME HOMOLOG ASLB-RELATED					
ECOLI|EnsemblGenome=b4014|UniProtKB=P08997	P08997	aceB	PTHR42902:SF1	MALATE SYNTHASE	MALATE SYNTHASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746	oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carbohydrate metabolic process#GO:0005975;glyoxylate metabolic process#GO:0046487;small molecule metabolic process#GO:0044281	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	transferase#PC00220;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2156|UniProtKB=P25737	P25737	lysP	PTHR43341:SF1	AMINO ACID PERMEASE	GENERAL AMINO-ACID PERMEASE GAP1	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171	transport#GO:0006810;amino acid transport#GO:0006865;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333	membrane#GO:0016020;cellular anatomical structure#GO:0110165	transporter#PC00227;amino acid transporter#PC00046	
ECOLI|EnsemblGenome=b3359|UniProtKB=P18335	P18335	argD	PTHR11986:SF122	AMINOTRANSFERASE CLASS III	ACETYLORNITHINE_SUCCINYLDIAMINOPIMELATE AMINOTRANSFERASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483	carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;L-arginine biosynthetic process#GO:0006526;proteinogenic amino acid biosynthetic process#GO:0170038	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	transaminase#PC00216	
ECOLI|EnsemblGenome=b2697|UniProtKB=P00957	P00957	alaS	PTHR11777:SF42	ALANYL-TRNA SYNTHETASE	ALANINE--TRNA LIGASE, CHLOROPLASTIC_MITOCHONDRIAL	hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101;carboxylic ester hydrolase activity#GO:0052689;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;deacylase activity#GO:0160215;catalytic activity#GO:0003824;ligase activity#GO:0016874;hydrolase activity, acting on ester bonds#GO:0016788	protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	aminoacyl-tRNA synthetase#PC00047	
ECOLI|EnsemblGenome=b3638|UniProtKB=P25531	P25531	yicR	PTHR30471:SF3	DNA REPAIR PROTEIN RADC	UPF0758 PROTEIN YEES-RELATED				DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b4224|UniProtKB=P08365	P08365	chpS	PTHR40516:SF1	ANTITOXIN CHPS-RELATED	ANTITOXIN CHPS-RELATED		regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255	transcription repressor complex#GO:0017053;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667		
ECOLI|EnsemblGenome=b0719|UniProtKB=P37909	P37909	ybgD	PTHR33420:SF11	FIMBRIAL SUBUNIT ELFA-RELATED	FIMBRIAL-LIKE PROTEIN		cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;cell adhesion#GO:0007155;single-species biofilm formation#GO:0044010	cellular anatomical structure#GO:0110165;cell projection#GO:0042995		
ECOLI|EnsemblGenome=b3806|UniProtKB=P00936	P00936	cyaA	PTHR38760:SF1	ADENYLATE CYCLASE	ADENYLATE CYCLASE	lyase activity#GO:0016829;adenylate cyclase activity#GO:0004016;catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849	nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;cyclic purine nucleotide metabolic process#GO:0052652;cyclic nucleotide metabolic process#GO:0009187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521		adenylate cyclase#PC00043;cyclase#PC00079	
ECOLI|EnsemblGenome=b2365|UniProtKB=P08555	P08555	dsdX	PTHR30354:SF6	GNT FAMILY GLUCONATE TRANSPORTER	D-SERINE TRANSPORTER DSDX	carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate transmembrane transporter activity#GO:0015144;monocarboxylic acid transmembrane transporter activity#GO:0008028	carbohydrate transmembrane transport#GO:0034219;carboxylic acid transmembrane transport#GO:1905039;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;carbohydrate transport#GO:0008643	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227;secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b4061|UniProtKB=P32701	P32701	pdeC	PTHR33121:SF60	CYCLIC DI-GMP PHOSPHODIESTERASE PDEF	CYCLIC DI-GMP PHOSPHODIESTERASE PDEC-RELATED	phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788	regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular process#GO:0050794	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121	
ECOLI|EnsemblGenome=b1087|UniProtKB=P0A729	P0A729	yceF	PTHR43213:SF10	BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED	7-METHYL-GTP PYROPHOSPHATASE	pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside triphosphate diphosphatase activity#GO:0047429;hydrolase activity#GO:0016787				
ECOLI|EnsemblGenome=b0894|UniProtKB=P18775	P18775	dmsA	PTHR43742:SF3	TRIMETHYLAMINE-N-OXIDE REDUCTASE	DIMETHYL SULFOXIDE REDUCTASE DMSA	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;metabolic process#GO:0008152;anaerobic respiration#GO:0009061;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980	periplasmic space#GO:0042597;extracellular region#GO:0005576;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313	reductase#PC00198	
ECOLI|EnsemblGenome=b0424|UniProtKB=Q46948	Q46948	yajL	PTHR48094:SF23	PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED	PROTEIN_NUCLEIC ACID DEGLYCASE 3	hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824	aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular response to toxic substance#GO:0097237;aldehyde catabolic process#GO:0046185;detoxification#GO:0098754;response to chemical#GO:0042221;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;ketone metabolic process#GO:0042180;cellular detoxification of aldehyde#GO:0110095;small molecule catabolic process#GO:0044282;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b3024|UniProtKB=P0ADU5	P0ADU5	ygiW	PTHR36571:SF1	PROTEIN YGIW	PROTEIN YGIW		response to cadmium ion#GO:0046686;response to metal ion#GO:0010038;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;response to chemical#GO:0042221;detoxification#GO:0098754;response to stress#GO:0006950;detoxification of inorganic compound#GO:0061687			
ECOLI|EnsemblGenome=b2089|UniProtKB=P0CF83	P0CF83	insF5	PTHR42648:SF5	TRANSPOSASE, PUTATIVE-RELATED	TRANSPOSASE INSF FOR INSERTION SEQUENCE IS3A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b2981|UniProtKB=Q46840	Q46840	yghO	PTHR41368:SF1	PROTEIN YGHO	PROTEIN YGHO					
ECOLI|EnsemblGenome=b2254|UniProtKB=P77757	P77757	arnC	PTHR48090:SF3	UNDECAPRENYL-PHOSPHATE 4-DEOXY-4-FORMAMIDO-L-ARABINOSE TRANSFERASE-RELATED	UNDECAPRENYL-PHOSPHATE 4-DEOXY-4-FORMAMIDO-L-ARABINOSE TRANSFERASE	glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;transferase#PC00220	
ECOLI|EnsemblGenome=b2739|UniProtKB=Q46891	Q46891	otnI	PTHR43489:SF6	ISOMERASE	HYDROXYPYRUVATE ISOMERASE-RELATED	isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824	aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;glyoxylate metabolic process#GO:0046487;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152		metabolite interconversion enzyme#PC00262;isomerase#PC00135	
ECOLI|EnsemblGenome=b0552|UniProtKB=P0CE50	P0CE50	insH2	PTHR35604:SF2	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640	nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b4291|UniProtKB=P13036	P13036	fecA	PTHR30442:SF0	IRON III  DICITRATE TRANSPORT PROTEIN FECA	FE(3+) DICITRATE TRANSPORT PROTEIN FECA		iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular localization#GO:0051641;siderophore-dependent iron import pathway#GO:0180060;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;iron import into cell#GO:0033212;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;metal ion transport#GO:0030001;iron coordination entity transport#GO:1901678;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;import into cell#GO:0098657;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;siderophore-iron import into cell#GO:0033214			
ECOLI|EnsemblGenome=b1176|UniProtKB=P18196	P18196	minC	PTHR34108:SF1	SEPTUM SITE-DETERMINING PROTEIN MINC	SEPTUM SITE-DETERMINING PROTEIN MINC	enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772	division septum assembly#GO:0000917;cellular component organization or biogenesis#GO:0071840;cytokinetic process#GO:0032506;cytokinesis#GO:0000910;cellular component assembly#GO:0022607;cell division#GO:0051301;cell cycle process#GO:0022402;cellular process#GO:0009987;cellular component organization#GO:0016043;cell septum assembly#GO:0090529;cellular component biogenesis#GO:0044085;cell cycle#GO:0007049	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell pole#GO:0060187;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b2099|UniProtKB=P76418	P76418	yegU	PTHR16222:SF43	ADP-RIBOSYLGLYCOHYDROLASE	SELENOPROTEIN J	hydrolase activity#GO:0016787;catalytic activity#GO:0003824			hydrolase#PC00121	
ECOLI|EnsemblGenome=b3228|UniProtKB=P0AFZ3	P0AFZ3	sspB	PTHR37486:SF1	STRINGENT STARVATION PROTEIN B	STRINGENT STARVATION PROTEIN B					
ECOLI|EnsemblGenome=b3932|UniProtKB=P0A7B8	P0A7B8	hslV	PTHR32194:SF0	METALLOPROTEASE TLDD	ATP-DEPENDENT PROTEASE SUBUNIT HSLV		protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	metalloprotease#PC00153	
ECOLI|EnsemblGenome=b3901|UniProtKB=P32156	P32156	rhaM	PTHR34389:SF2	L-RHAMNOSE MUTAROTASE	L-RHAMNOSE MUTAROTASE	racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;isomerase activity#GO:0016853				
ECOLI|EnsemblGenome=b3925|UniProtKB=P0A9C9	P0A9C9	glpX	PTHR30447:SF0	FRUCTOSE-1,6-BISPHOSPHATASE CLASS 2	FRUCTOSE-1,6-BISPHOSPHATASE 1 CLASS 2-RELATED	hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;sugar-phosphatase activity#GO:0050308;hydrolase activity, acting on ester bonds#GO:0016788	organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;gluconeogenesis#GO:0006094;cellular process#GO:0009987;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;small molecule biosynthetic process#GO:0044283;glucose metabolic process#GO:0006006;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;phosphorus metabolic process#GO:0006793;hexose biosynthetic process#GO:0019319;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975		carbohydrate phosphatase#PC00066;hydrolase#PC00121;phosphatase#PC00181	
ECOLI|EnsemblGenome=b3310|UniProtKB=P0ADY3	P0ADY3	rplN	PTHR11761:SF3	50S/60S RIBOSOMAL PROTEIN L14/L23	LARGE RIBOSOMAL SUBUNIT PROTEIN UL14	binding#GO:0005488;rRNA binding#GO:0019843;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198		intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165	translational protein#PC00263;ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b3870|UniProtKB=P0A9C5	P0A9C5	glnA	PTHR43407:SF2	GLUTAMINE SYNTHETASE	GLUTAMINE SYNTHETASE	ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879	proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;response to nutrient levels#GO:0031667;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;chemical homeostasis#GO:0048878;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;homeostatic process#GO:0042592;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436	membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	ligase#PC00142	Glutamine glutamate conversion#P02745>Glutamine synthetase#P02968
ECOLI|EnsemblGenome=b0711|UniProtKB=P0AAV4	P0AAV4	pxpB	PTHR34698:SF2	5-OXOPROLINASE SUBUNIT B	5-OXOPROLINASE SUBUNIT B					
ECOLI|EnsemblGenome=b1438|UniProtKB=P67697	P67697	hicB	PTHR34504:SF2	ANTITOXIN HICB	ANTITOXIN HICB		regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468			
ECOLI|EnsemblGenome=b1162|UniProtKB=P75989	P75989	bluR	PTHR30204:SF67	REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR	HTH-TYPE TRANSCRIPTIONAL REGULATOR MLRA-RELATED	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255		helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b0106|UniProtKB=P36646	P36646	hofC	PTHR30012:SF7	GENERAL SECRETION PATHWAY PROTEIN	PROTEIN TRANSPORT PROTEIN HOFC HOMOLOG		transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;establishment of localization#GO:0051234;protein secretion by the type II secretion system#GO:0015628;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;secretion by cell#GO:0032940;protein transport#GO:0015031;protein secretion#GO:0009306;localization#GO:0051179;transmembrane transport#GO:0055085;secretion#GO:0046903;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b0134|UniProtKB=P31057	P31057	panB	PTHR20881:SF2	3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE	3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE-RELATED	ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;magnesium ion binding#GO:0000287;metal ion binding#GO:0046872;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740	small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	methyltransferase#PC00155	Pantothenate biosynthesis#P02761>3-methyl-2-oxobutanoate hydroxymethyltransferase#P03067
ECOLI|EnsemblGenome=b3484|UniProtKB=P28912	P28912	yhhI	PTHR30298:SF0	H REPEAT-ASSOCIATED PREDICTED TRANSPOSASE	PROTEIN YBFL-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b1081|UniProtKB=P75942	P75942	flgJ	PTHR33308:SF9	PEPTIDOGLYCAN HYDROLASE FLGJ	PEPTIDOGLYCAN HYDROLASE FLGJ		cell motility#GO:0048870;bacterial-type flagellum-dependent cell motility#GO:0071973;cellular process#GO:0009987;cilium or flagellum-dependent cell motility#GO:0001539;archaeal or bacterial-type flagellum-dependent cell motility#GO:0097588		metabolite interconversion enzyme#PC00262;hydrolase#PC00121	
ECOLI|EnsemblGenome=b0945|UniProtKB=P0A7E1	P0A7E1	pyrD	PTHR48109:SF6	DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL-RELATED	DIHYDROOROTATE DEHYDROGENASE (QUINONE)	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627	nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;pyrimidine nucleobase metabolic process#GO:0006206;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;pyrimidine-containing compound metabolic process#GO:0072527		metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	De novo pyrimidine ribonucleotides biosythesis#P02740>Dihydrooratate oxidase#P02927
ECOLI|EnsemblGenome=b2775|UniProtKB=P77031	P77031	yqcE	PTHR43184:SF12	MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B	INNER MEMBRANE PROTEIN YQCE				transporter#PC00227	
ECOLI|EnsemblGenome=b0742|UniProtKB=P45955	P45955	cpoB	PTHR37423:SF7	SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE-RELATED	CELL DIVISION COORDINATOR CPOB		cell division#GO:0051301;cellular process#GO:0009987	extracellular region#GO:0005576;periplasmic space#GO:0042597;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313		
ECOLI|EnsemblGenome=b0638|UniProtKB=P52086	P52086	cobC	PTHR48100:SF75	BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED	ADENOSYLCOBALAMIN_ALPHA-RIBAZOLE PHOSPHATASE	catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578		cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	hydrolase#PC00121;phosphatase#PC00181	Cobalamin biosynthesis#P02735>Ribazole-5-phosphate phosphatase#P02881
ECOLI|EnsemblGenome=b1511|UniProtKB=P77432	P77432	lsrK	PTHR43095:SF1	SUGAR KINASE	AUTOINDUCER-2 KINASE	transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824			carbohydrate kinase#PC00065	Ascorbate degradation#P02729>L-xylulose kinase#P02849
ECOLI|EnsemblGenome=b1049|UniProtKB=P62517	P62517	mdoH	PTHR43867:SF5	CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]	GLUCANS BIOSYNTHESIS GLUCOSYLTRANSFERASE H	hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757	polysaccharide biosynthetic process#GO:0000271;cellulose biosynthetic process#GO:0030244;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;glucan biosynthetic process#GO:0009250;beta-glucan biosynthetic process#GO:0051274;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;beta-glucan metabolic process#GO:0051273;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;polysaccharide metabolic process#GO:0005976	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b0804|UniProtKB=P75779	P75779	ybiX	PTHR41536:SF1	PKHD-TYPE HYDROXYLASE YBIX	PKHD-TYPE HYDROXYLASE YBIX		cellular process#GO:0009987;response to stress#GO:0006950;monoatomic ion homeostasis#GO:0050801;DNA damage response#GO:0006974;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;cellular response to stimulus#GO:0051716;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;response to stimulus#GO:0050896;intracellular iron ion homeostasis#GO:0006879;cellular response to stress#GO:0033554;inorganic ion homeostasis#GO:0098771		metabolite interconversion enzyme#PC00262;hydroxylase#PC00122	
ECOLI|EnsemblGenome=b0882|UniProtKB=P0ABH9	P0ABH9	clpA	PTHR11638:SF111	ATP-DEPENDENT CLP PROTEASE	ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPA	ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818	cellular response to stress#GO:0033554;response to heat#GO:0009408;cellular response to heat#GO:0034605;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to temperature stimulus#GO:0009266	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	protease#PC00190;protein modifying enzyme#PC00260	
ECOLI|EnsemblGenome=b1156|UniProtKB=P09153	P09153	tfaE	PTHR34413:SF2	PROPHAGE TAIL FIBER ASSEMBLY PROTEIN HOMOLOG TFAE-RELATED-RELATED	PROPHAGE TAIL FIBER ASSEMBLY PROTEIN HOMOLOG TFAE-RELATED				chaperone#PC00072	
ECOLI|EnsemblGenome=b0153|UniProtKB=P06972	P06972	fhuB	PTHR30472:SF37	FERRIC ENTEROBACTIN TRANSPORT SYSTEM PERMEASE PROTEIN	FE(3+) DICITRATE TRANSPORT SYSTEM PERMEASE PROTEIN FECD-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	import into cell#GO:0098657;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;iron coordination entity transport#GO:1901678;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;siderophore-iron import into cell#GO:0033214;monoatomic ion homeostasis#GO:0050801;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular localization#GO:0051641;siderophore-dependent iron import pathway#GO:0180060;monoatomic ion transport#GO:0006811;iron ion transport#GO:0006826;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;intracellular iron ion homeostasis#GO:0006879;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;iron import into cell#GO:0033212	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b2964|UniProtKB=P0AFF4	P0AFF4	nupG	PTHR23522:SF4	BLL5896 PROTEIN	NUCLEOSIDE PERMEASE NUPG-RELATED	nucleoside transmembrane transporter activity#GO:0005337;nucleobase-containing compound transmembrane transporter activity#GO:0015932;carbohydrate derivative transmembrane transporter activity#GO:1901505;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b2798|UniProtKB=P38506	P38506	ygdG	PTHR42646:SF2	FLAP ENDONUCLEASE XNI	5'-3' EXONUCLEASE FAMILY PROTEIN	nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888	DNA replication#GO:0006260;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;DNA strand elongation involved in DNA replication#GO:0006271;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170			
ECOLI|EnsemblGenome=b4336|UniProtKB=P39385	P39385	yjiN	PTHR38442:SF1	INNER MEMBRANE PROTEIN-RELATED	DUF445 FAMILY PROTEIN			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b3994|UniProtKB=P30136	P30136	thiC	PTHR30557:SF3	THIAMINE BIOSYNTHESIS PROTEIN THIC	PHOSPHOMETHYLPYRIMIDINE SYNTHASE	catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829	small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;sulfur compound metabolic process#GO:0006790;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b2837|UniProtKB=P03024	P03024	galR	PTHR30146:SF98	LACI-RELATED TRANSCRIPTIONAL REPRESSOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR GALR	DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889		Lambda repressor-like transcription factor#PC00245;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b2889|UniProtKB=Q46822	Q46822	idi	PTHR10885:SF0	ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE	ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE				isomerase#PC00135	
ECOLI|EnsemblGenome=b0857|UniProtKB=P0AFL1	P0AFL1	potI	PTHR43848:SF2	PUTRESCINE TRANSPORT SYSTEM PERMEASE PROTEIN POTI	PUTRESCINE TRANSPORT SYSTEM PERMEASE PROTEIN POTI	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;polyamine transmembrane transporter activity#GO:0015203		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b1338|UniProtKB=P77357	P77357	abgA	PTHR30575:SF3	PEPTIDASE M20	PEPTIDASE M20 DIMERISATION DOMAIN-CONTAINING PROTEIN	catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233	cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	metalloprotease#PC00153	
ECOLI|EnsemblGenome=b3895|UniProtKB=P32177	P32177	fdhD	PTHR30592:SF5	FORMATE DEHYDROGENASE	SULFUR CARRIER PROTEIN FDHD	molecular carrier activity#GO:0140104			oxidoreductase#PC00176;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b3824|UniProtKB=P0AG34	P0AG34	rhtB	PTHR30086:SF14	ARGININE EXPORTER PROTEIN ARGO	HOMOSERINE_HOMOSERINE LACTONE EFFLUX PROTEIN	transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;neutral L-amino acid transmembrane transporter activity#GO:0015175;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179	carboxylic acid transmembrane transport#GO:1905039;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;L-alpha-amino acid transmembrane transport#GO:1902475;cellular process#GO:0009987;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b2308|UniProtKB=P52094	P52094	hisQ	PTHR30133:SF1	CATIONIC AMINO ACID TRANSPORTER, MEMBRANE COMPONENT	HISTIDINE_LYSINE_ARGININE_ORNITHINE TRANSPORT SYSTEM PERMEASE PROTEIN HISQ			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	secondary carrier transporter#PC00258;amino acid transporter#PC00046	
ECOLI|EnsemblGenome=b3421|UniProtKB=P46850	P46850	rtcB	PTHR43749:SF2	RNA-SPLICING LIGASE RTCB	RNA-SPLICING LIGASE RTCB		nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259		RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b0608|UniProtKB=P77316	P77316	ybdR	PTHR42813:SF2	ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE	ALCOHOL DEHYDROGENASE (EUROFUNG)				oxidoreductase#PC00176;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b4311|UniProtKB=P69856	P69856	nanC	PTHR38105:SF2	OUTER MEMBRANE PROTEIN-RELATED-RELATED	N-ACETYLNEURAMINIC ACID OUTER MEMBRANE CHANNEL PROTEIN NANC-RELATED	wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	transport#GO:0006810;carbohydrate transport#GO:0008643;establishment of localization#GO:0051234;localization#GO:0051179	outer membrane#GO:0019867;extracellular region#GO:0005576;membrane#GO:0016020;cell outer membrane#GO:0009279;external encapsulating structure#GO:0030312;cell envelope#GO:0030313;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2517|UniProtKB=P36979	P36979	rlmN	PTHR30544:SF10	23S RRNA METHYLTRANSFERASE	DUAL-SPECIFICITY RNA METHYLTRANSFERASE RLMN	transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	RNA methyltransferase#PC00033	
ECOLI|EnsemblGenome=b4054|UniProtKB=P04693	P04693	tyrB	PTHR11879:SF37	ASPARTATE AMINOTRANSFERASE	AROMATIC-AMINO-ACID AMINOTRANSFERASE	transaminase activity#GO:0008483;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;protein binding#GO:0005515;catalytic activity#GO:0003824;transferase activity#GO:0016740;identical protein binding#GO:0042802;heterocyclic compound binding#GO:1901363	cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;aromatic amino acid biosynthetic process#GO:0009073;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;proteinogenic amino acid biosynthetic process#GO:0170038	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	metabolite interconversion enzyme#PC00262;transaminase#PC00216;transferase#PC00220	Tyrosine biosynthesis#P02784>Aromatic amino acid aminotransferase#P03213;Phenylalanine biosynthesis#P02765>Aromatic amino acid aminotransferase#P03101
ECOLI|EnsemblGenome=b2811|UniProtKB=P0AGF2	P0AGF2	csdE	PTHR43597:SF8	SULFUR ACCEPTOR PROTEIN CSDE	SULFUR ACCEPTOR PROTEIN CSDE	molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;molecular carrier activity#GO:0140104;enzyme activator activity#GO:0008047	biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187	catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;sulfurtransferase complex#GO:1990228;cytoplasm#GO:0005737		
ECOLI|EnsemblGenome=b0386|UniProtKB=P0A9L8	P0A9L8	proC	PTHR11645:SF0	PYRROLINE-5-CARBOXYLATE REDUCTASE	PYRROLINE-5-CARBOXYLATE REDUCTASE	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;proteinogenic amino acid biosynthetic process#GO:0170038;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281		metabolite interconversion enzyme#PC00262;reductase#PC00198	Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113
ECOLI|EnsemblGenome=b0398|UniProtKB=P0AG76	P0AG76	sbcD	PTHR30337:SF0	COMPONENT OF ATP-DEPENDENT DSDNA EXONUCLEASE	NUCLEASE SBCCD SUBUNIT D				exodeoxyribonuclease#PC00098	
ECOLI|EnsemblGenome=b3699|UniProtKB=P0AES6	P0AES6	gyrB	PTHR45866:SF13	DNA GYRASE/TOPOISOMERASE SUBUNIT B	DNA GYRASE SUBUNIT B	catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094	nucleobase-containing compound metabolic process#GO:0006139;organelle organization#GO:0006996;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;metabolic process#GO:0008152;DNA metabolic process#GO:0006259	protein-containing complex#GO:0032991;catalytic complex#GO:1902494	DNA metabolism protein#PC00009;DNA topoisomerase#PC00017	
ECOLI|EnsemblGenome=b2541|UniProtKB=P0CI31	P0CI31	hcaB	PTHR43943:SF17	DEHYDROGENASE/REDUCTASE (SDR FAMILY) MEMBER 4	3-PHENYLPROPIONATE-DIHYDRODIOL_CINNAMIC ACID-DIHYDRODIOL DEHYDROGENASE				metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b0895|UniProtKB=P18776	P18776	dmsB	PTHR43177:SF5	PROTEIN NRFC	ANAEROBIC DIMETHYL SULFOXIDE REDUCTASE CHAIN B-RELATED	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824	anaerobic respiration#GO:0009061;anaerobic electron transport chain#GO:0019645;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;electron transport chain#GO:0022900;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152		oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3170|UniProtKB=P0A8A8	P0A8A8	rimP	PTHR33867:SF1	RIBOSOME MATURATION FACTOR RIMP	RIBOSOME MATURATION FACTOR RIMP					
ECOLI|EnsemblGenome=b3413|UniProtKB=P46846	P46846	gntX	PTHR47505:SF1	DNA UTILIZATION PROTEIN YHGH	DNA UTILIZATION PROTEIN YHGH					
ECOLI|EnsemblGenome=b3087|UniProtKB=P42599	P42599	ygjR	PTHR43054:SF1	FAMILY NOT NAMED	SCYLLO-INOSITOL 2-DEHYDROGENASE (NADP(+)) IOLU	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491				
ECOLI|EnsemblGenome=b2046|UniProtKB=P77377	P77377	wzxC	PTHR30250:SF10	PST FAMILY PREDICTED COLANIC ACID TRANSPORTER	LIPOPOLYSACCHARIDE BIOSYNTHESIS PROTEIN WZXC				transporter#PC00227	
ECOLI|EnsemblGenome=b2719|UniProtKB=P16433	P16433	hycG	PTHR42989:SF1	HYDROGENASE-4 COMPONENT I	FORMATE HYDROGENLYASE SUBUNIT 7-RELATED		cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;anaerobic respiration#GO:0009061;anaerobic electron transport chain#GO:0019645;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787	protein-containing complex#GO:0032991;oxidoreductase complex#GO:1990204;catalytic complex#GO:1902494	metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1019|UniProtKB=P31545	P31545	efeB	PTHR30521:SF4	DEFERROCHELATASE/PEROXIDASE	DEFERROCHELATASE	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;heme binding#GO:0020037;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;tetrapyrrole binding#GO:0046906;binding#GO:0005488		cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	peroxidase#PC00180	
ECOLI|EnsemblGenome=b1676|UniProtKB=P0AD61	P0AD61	pykF	PTHR11817:SF135	PYRUVATE KINASE	PYRUVATE KINASE I	transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;pyruvate kinase activity#GO:0004743;phosphotransferase activity, alcohol group as acceptor#GO:0016773	nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleotide catabolic process#GO:0009166;carbohydrate metabolic process#GO:0005975;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;purine ribonucleotide catabolic process#GO:0009154;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;primary metabolic process#GO:0044238;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine-containing compound catabolic process#GO:0072523;ADP catabolic process#GO:0046032;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;oxoacid metabolic process#GO:0043436;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	kinase#PC00137	Pyruvate metabolism#P02772>Pyruvate Kinase#P03132
ECOLI|EnsemblGenome=b0256|UniProtKB=P0CF88	P0CF88	insI1	PTHR10948:SF23	TRANSPOSASE	TRANSPOSASE INSI FOR INSERTION SEQUENCE ELEMENT IS30A-RELATED	catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640	DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139		viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b3737|UniProtKB=P68699	P68699	atpE	PTHR10031:SF0	ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL	ATPASE PROTEIN 9				primary active transporter#PC00068;transporter#PC00227;ATP synthase#PC00002	
ECOLI|EnsemblGenome=b3691|UniProtKB=P0AA76	P0AA76	dgoT	PTHR11662:SF333	SOLUTE CARRIER FAMILY 17	D-GALACTONATE TRANSPORTER				secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b2545|UniProtKB=P77360	P77360	yphC	PTHR43350:SF19	NAD-DEPENDENT ALCOHOL DEHYDROGENASE	D-GULOSIDE 3-DEHYDROGENASE	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824			metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b0269|UniProtKB=P77596	P77596	yagF	PTHR43661:SF3	D-XYLONATE DEHYDRATASE	D-XYLONATE DEHYDRATASE YAGF-RELATED	catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	dehydratase#PC00091	Valine biosynthesis#P02785>Dihydroxy isovalerate dehydratase#P03218;Isoleucine biosynthesis#P02748>Dihydroxyacid dehydratase#P02998
ECOLI|EnsemblGenome=b2103|UniProtKB=P76422	P76422	thiD	PTHR20858:SF17	PHOSPHOMETHYLPYRIMIDINE KINASE	HYDROXYMETHYLPYRIMIDINE_PHOSPHOMETHYLPYRIMIDINE KINASE THI20-RELATED	catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;phosphotransferase activity, phosphate group as acceptor#GO:0016776	biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;sulfur compound metabolic process#GO:0006790;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	kinase#PC00137	Thiamin biosynthesis#P02779>Hydroxymethylpyrimidine phosphate kinase#P03170
ECOLI|EnsemblGenome=b4087|UniProtKB=P32721	P32721	alsA	PTHR43790:SF10	CARBOHYDRATE TRANSPORT ATP-BINDING PROTEIN MG119-RELATED	D-ALLOSE IMPORT ATP-BINDING PROTEIN ALSA-RELATED	sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b3502|UniProtKB=P0AB93	P0AB93	arsB	PTHR43302:SF20	TRANSPORTER ARSB-RELATED	ARSENICAL PUMP MEMBRANE PROTEIN	secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804	transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	primary active transporter#PC00068;transporter#PC00227	
ECOLI|EnsemblGenome=b2825|UniProtKB=P08371	P08371	ppdB	PTHR39583:SF3	TYPE II SECRETION SYSTEM PROTEIN J-RELATED	PREPILIN PEPTIDASE-DEPENDENT PROTEIN B		protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion#GO:0046903;transmembrane transport#GO:0055085;protein secretion#GO:0009306;localization#GO:0051179;protein transport#GO:0015031;secretion by cell#GO:0032940;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;transport#GO:0006810;protein transmembrane transport#GO:0071806;establishment of localization#GO:0051234;protein secretion by the type II secretion system#GO:0015628;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104	membrane#GO:0016020;type II protein secretion system complex#GO:0015627;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b1491|UniProtKB=P64426	P64426	digH	PTHR43405:SF1	GLYCOSYL HYDROLASE DIGH	GLYCOSYL HYDROLASE DIGH					
ECOLI|EnsemblGenome=b0594|UniProtKB=P10378	P10378	entE	PTHR43859:SF70	ACYL-ACTIVATING ENZYME	ENTEROBACTIN SYNTHASE COMPONENT E	catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874	biosynthetic process#GO:0009058;siderophore biosynthetic process#GO:0019290;phenol-containing compound biosynthetic process#GO:0046189;antibiotic biosynthetic process#GO:0017000;cellular process#GO:0009987;phenol-containing compound metabolic process#GO:0018958;secondary metabolic process#GO:0019748;peptide metabolic process#GO:0006518;secondary metabolite biosynthetic process#GO:0044550;metabolic process#GO:0008152;siderophore metabolic process#GO:0009237		ligase#PC00142	
ECOLI|EnsemblGenome=b1807|UniProtKB=P76256	P76256	tsaB	PTHR11735:SF11	TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE	TRNA THREONYLCARBAMOYLADENOSINE BIOSYNTHESIS PROTEIN TSAB			cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	RNA metabolism protein#PC00031;RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b2938|UniProtKB=P21170	P21170	speA	PTHR43295:SF9	ARGININE DECARBOXYLASE	BIOSYNTHETIC ARGININE DECARBOXYLASE	carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829	polyamine metabolic process#GO:0006595;cellular process#GO:0009987;metabolic process#GO:0008152;amine metabolic process#GO:0009308;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;polyamine biosynthetic process#GO:0006596		metabolite interconversion enzyme#PC00262;decarboxylase#PC00089	
ECOLI|EnsemblGenome=b3906|UniProtKB=P09378	P09378	rhaR	PTHR43280:SF13	ARAC-FAMILY TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL ACTIVATOR RHAR	nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556		helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b2457|UniProtKB=P0ABF4	P0ABF4	eutM	PTHR33941:SF10	PROPANEDIOL UTILIZATION PROTEIN PDUA	BACTERIAL MICROCOMPARTMENT SHELL PROTEIN EUTM					
ECOLI|EnsemblGenome=b1222|UniProtKB=P0AFA2	P0AFA2	narX	PTHR24421:SF51	NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED	NITRATE_NITRITE SENSOR PROTEIN NARX	protein histidine kinase activity#GO:0004673;catalytic activity, acting on a protein#GO:0140096;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;phosphorelay sensor kinase activity#GO:0000155;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672	cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b3697|UniProtKB=P0A8Y5	P0A8Y5	yidA	PTHR10000:SF8	PHOSPHOSERINE PHOSPHATASE	HAD SUPERFAMILY HYDROLASE-LIKE, TYPE 3	small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;magnesium ion binding#GO:0000287;cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578		cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	protein phosphatase#PC00195	
ECOLI|EnsemblGenome=b3127|UniProtKB=P0AA80	P0AA80	garP	PTHR11662:SF399	SOLUTE CARRIER FAMILY 17	MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN				secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b1288|UniProtKB=P0AEK4	P0AEK4	fabI	PTHR43159:SF2	ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE	ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH] FABI	oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330		oxidoreductase#PC00176;reductase#PC00198	
ECOLI|EnsemblGenome=b4329|UniProtKB=P0AEH8	P0AEH8	yjiG	PTHR35793:SF2	INNER MEMBRANE PROTEIN YJIG	INNER MEMBRANE PROTEIN YJIG			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b3945|UniProtKB=P0A9S5	P0A9S5	gldA	PTHR43616:SF6	GLYCEROL DEHYDROGENASE	GLYCEROL DEHYDROGENASE	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3585|UniProtKB=P37682	P37682	yiaU	PTHR30419:SF14	HTH-TYPE TRANSCRIPTIONAL REGULATOR YBHD	POSSIBLE TRANSCRIPTIONAL REGULATOR	binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b4114|UniProtKB=P30845	P30845	eptA	PTHR30443:SF0	INNER MEMBRANE PROTEIN	PHOSPHOETHANOLAMINE TRANSFERASE EPTA	catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, phosphate group as acceptor#GO:0016776	lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oligosaccharide metabolic process#GO:0009311;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;polysaccharide biosynthetic process#GO:0000271;oligosaccharide biosynthetic process#GO:0009312;lipopolysaccharide metabolic process#GO:0008653;primary metabolic process#GO:0044238;lipopolysaccharide biosynthetic process#GO:0009103;lipopolysaccharide core region biosynthetic process#GO:0009244;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;liposaccharide metabolic process#GO:1903509	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b4539|UniProtKB=P69348	P69348	yoeB	PTHR38039:SF2	TOXIN YOEB	TOXIN YOEB	nuclease activity#GO:0004518;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640				
ECOLI|EnsemblGenome=b4138|UniProtKB=P0ABN5	P0ABN5	dcuA	PTHR36106:SF2	ANAEROBIC C4-DICARBOXYLATE TRANSPORTER DCUB	C4-DICARBOXYLATE TRANSPORTER DCUA	carboxylic acid transmembrane transporter activity#GO:0046943;C4-dicarboxylate transmembrane transporter activity#GO:0015556;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;succinate transmembrane transporter activity#GO:0015141;active transmembrane transporter activity#GO:0022804;dicarboxylic acid transmembrane transporter activity#GO:0005310	anaerobic respiration#GO:0009061;dicarboxylic acid transport#GO:0006835;cellular process#GO:0009987;cellular respiration#GO:0045333;establishment of localization#GO:0051234;energy derivation by oxidation of organic compounds#GO:0015980;localization#GO:0051179;metabolic process#GO:0008152;organic acid transport#GO:0015849;C4-dicarboxylate transport#GO:0015740;transport#GO:0006810;carboxylic acid transport#GO:0046942;generation of precursor metabolites and energy#GO:0006091	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b3477|UniProtKB=P33591	P33591	nikB	PTHR43163:SF10	DIPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN DPPB-RELATED	DIPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN DPPB-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;dipeptide transmembrane transporter activity#GO:0071916;oligopeptide transmembrane transporter activity#GO:0035673		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b3722|UniProtKB=P08722	P08722	bglF	PTHR30175:SF1	PHOSPHOTRANSFERASE SYSTEM TRANSPORT PROTEIN	PTS SYSTEM N-ACETYLMURAMIC ACID-SPECIFIC EIIBC COMPONENT-RELATED				secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b1955|UniProtKB=P76329	P76329	yedP	PTHR10000:SF59	PHOSPHOSERINE PHOSPHATASE	MANNOSYL-3-PHOSPHOGLYCERATE PHOSPHATASE	ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;magnesium ion binding#GO:0000287;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	protein phosphatase#PC00195	
ECOLI|EnsemblGenome=b3608|UniProtKB=P0A6S7	P0A6S7	gpsA	PTHR11728:SF48	GLYCEROL-3-PHOSPHATE DEHYDROGENASE	GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(P)+]	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491	organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	dehydrogenase#PC00092;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2735|UniProtKB=P52598	P52598	ygbI	PTHR30363:SF58	HTH-TYPE TRANSCRIPTIONAL REGULATOR SRLR-RELATED	DEOR-FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN-RELATED	sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219		helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b2002|UniProtKB=P76362	P76362	yeeS	PTHR30471:SF3	DNA REPAIR PROTEIN RADC	UPF0758 PROTEIN YEES-RELATED				DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b1918|UniProtKB=P0AFT2	P0AFT2	tcyL	PTHR30614:SF0	MEMBRANE COMPONENT OF AMINO ACID ABC TRANSPORTER	L-CYSTINE TRANSPORT SYSTEM PERMEASE PROTEIN TCYL	L-amino acid transmembrane transporter activity#GO:0015179;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171	carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;amino acid transport#GO:0006865;neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234;localization#GO:0051179;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	amino acid transporter#PC00046	
ECOLI|EnsemblGenome=b3394|UniProtKB=P64634	P64634	hofN	PTHR40278:SF1	DNA UTILIZATION PROTEIN HOFN	DNA UTILIZATION PROTEIN HOFN					
ECOLI|EnsemblGenome=b0101|UniProtKB=P0A8H8	P0A8H8	yacG	PTHR36150:SF1	DNA GYRASE INHIBITOR YACG	DNA GYRASE INHIBITOR YACG	enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857				
ECOLI|EnsemblGenome=b4113|UniProtKB=P30843	P30843	basR	PTHR48111:SF75	REGULATOR OF RPOS	TRANSCRIPTIONAL REGULATORY PROTEIN BASR	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;molecular transducer activity#GO:0060089;double-stranded DNA binding#GO:0003690	regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;cytosol#GO:0005829	helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b3165|UniProtKB=P0ADZ4	P0ADZ4	rpsO	PTHR23321:SF26	RIBOSOMAL PROTEIN S15, BACTERIAL AND ORGANELLAR	SMALL RIBOSOMAL SUBUNIT PROTEIN US15	structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735	protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238		ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b0751|UniProtKB=P0AFK2	P0AFK2	pnuC	PTHR36122:SF2	NICOTINAMIDE RIBOSIDE TRANSPORTER PNUC	NICOTINAMIDE RIBOSIDE TRANSPORTER PNUC	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleoside transmembrane transporter activity#GO:0005337		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b4056|UniProtKB=P0AF48	P0AF48	yjbQ	PTHR30615:SF8	UNCHARACTERIZED PROTEIN YJBQ-RELATED	UPF0047 PROTEIN C4A8.02C					
ECOLI|EnsemblGenome=b2867|UniProtKB=Q46800	Q46800	xdhB	PTHR42659:SF9	XANTHINE DEHYDROGENASE SUBUNIT C-RELATED	XANTHINE DEHYDROGENASE FAD-BINDING SUBUNIT XDHB-RELATED	catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491			oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b3311|UniProtKB=P0AG63	P0AG63	rpsQ	PTHR10744:SF1	40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER	SMALL RIBOSOMAL SUBUNIT PROTEIN US17	structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735		ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228	ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b0624|UniProtKB=P37002	P37002	fluC	PTHR28259:SF1	FLUORIDE EXPORT PROTEIN 1-RELATED	FLUORIDE EXPORT PROTEIN 1-RELATED	monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509	detoxification of inorganic compound#GO:0061687;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;response to chemical#GO:0042221;monoatomic ion transmembrane transport#GO:0034220;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;transport#GO:0006810;establishment of localization#GO:0051234;monoatomic anion transport#GO:0006820;cellular response to stimulus#GO:0051716;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;export from cell#GO:0140352;cellular response to chemical stimulus#GO:0070887;cellular detoxification#GO:1990748;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b2486|UniProtKB=P77437	P77437	hyfF	PTHR42682:SF5	HYDROGENASE-4 COMPONENT F	HYDROGENASE-4 COMPONENT F		response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;DNA damage response#GO:0006974;cellular response to stress#GO:0033554		oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b4200|UniProtKB=P02358	P02358	rpsF	PTHR21011:SF18	MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S6	SMALL RIBOSOMAL SUBUNIT PROTEIN BS6	structural molecule activity#GO:0005198;RNA binding#GO:0003723;rRNA binding#GO:0019843;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735		intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626	ribosomal protein#PC00202;translational protein#PC00263	
ECOLI|EnsemblGenome=b2516|UniProtKB=P27434	P27434	rodZ	PTHR34475:SF1	CYTOSKELETON PROTEIN RODZ	CYTOSKELETON PROTEIN RODZ			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b3060|UniProtKB=P45463	P45463	ttdR	PTHR30537:SF5	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL ACTIVATOR TTDR-RELATED	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090		helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b0004|UniProtKB=P00934	P00934	thrC	PTHR42690:SF1	THREONINE SYNTHASE FAMILY MEMBER	THREONINE SYNTHASE					Threonine biosynthesis#P02781>Threonine synthase#P03190;Vitamin B6 metabolism#P02787>Threonine synthase#P03242
ECOLI|EnsemblGenome=b2961|UniProtKB=P17802	P17802	mutY	PTHR42944:SF2	ADENINE DNA GLYCOSYLASE	ADENINE DNA GLYCOSYLASE	catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on glycosyl bonds#GO:0016798;damaged DNA binding#GO:0003684;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;hydrolase activity#GO:0016787;DNA N-glycosylase activity#GO:0019104;nucleic acid binding#GO:0003676;binding#GO:0005488	nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;mismatch repair#GO:0006298;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170		DNA glycosylase#PC00010;DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b3021|UniProtKB=Q46864	Q46864	mqsA	PTHR36511:SF4	MERR FAMILY BACTERIAL REGULATORY PROTEIN	ANTITOXIN MQSA	sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789		Lambda repressor-like transcription factor#PC00245	
ECOLI|EnsemblGenome=b2152|UniProtKB=P25747	P25747	yeiB	PTHR30590:SF2	INNER MEMBRANE PROTEIN	DUF418 DOMAIN-CONTAINING PROTEIN			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b3955|UniProtKB=P0CB39	P0CB39	eptC	PTHR30443:SF2	INNER MEMBRANE PROTEIN	PHOSPHOETHANOLAMINE TRANSFERASE EPTC	phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740	oligosaccharide biosynthetic process#GO:0009312;lipopolysaccharide metabolic process#GO:0008653;polysaccharide biosynthetic process#GO:0000271;lipopolysaccharide core region biosynthetic process#GO:0009244;lipopolysaccharide biosynthetic process#GO:0009103;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;liposaccharide metabolic process#GO:1903509;primary metabolic process#GO:0044238;oligosaccharide metabolic process#GO:0009311;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b3409|UniProtKB=P33650	P33650	feoB	PTHR43185:SF1	FERROUS IRON TRANSPORT PROTEIN B	FE(2+) TRANSPORTER FEOB	metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;iron ion transmembrane transporter activity#GO:0005381;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transition metal ion transmembrane transporter activity#GO:0046915	transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;iron ion transport#GO:0006826;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;iron import into cell#GO:0033212;intracellular monoatomic ion homeostasis#GO:0006873;intracellular iron ion homeostasis#GO:0006879;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;iron ion transmembrane transport#GO:0034755;establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;iron ion import across plasma membrane#GO:0098711;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transfer/carrier protein#PC00219	
ECOLI|EnsemblGenome=b2770|UniProtKB=Q46908	Q46908	ygcR	PTHR21294:SF22	ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT	PROTEIN FIXA-RELATED				oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0889|UniProtKB=P0ACJ0	P0ACJ0	lrp	PTHR30154:SF0	LEUCINE-RESPONSIVE REGULATORY PROTEIN	LEUCINE-RESPONSIVE REGULATORY PROTEIN	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	response to nitrogen compound#GO:1901698;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;response to acid chemical#GO:0001101	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b1833|UniProtKB=P0AD03	P0AD03	letA	PTHR30462:SF1	INTERMEMBRANE TRANSPORT PROTEIN PQIB-RELATED	LIPOPHILIC ENVELOPE-SPANNING TUNNEL PROTEIN A		cellular process#GO:0009987;cellular component organization#GO:0016043;membrane organization#GO:0061024;cellular component organization or biogenesis#GO:0071840	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b2696|UniProtKB=P69913	P69913	csrA	PTHR34984:SF1	CARBON STORAGE REGULATOR	CARBON STORAGE REGULATOR			cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b0950|UniProtKB=P0AFL9	P0AFL9	pqiA	PTHR30462:SF3	INTERMEMBRANE TRANSPORT PROTEIN PQIB-RELATED	INTERMEMBRANE TRANSPORT PROTEIN PQIA		cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;cellular component organization#GO:0016043;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b1563|UniProtKB=P0C077	P0C077	relE	PTHR35601:SF2	TOXIN RELE	MRNA INTERFERASE TOXIN RELE	catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;endonuclease activity#GO:0004519	RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007			
ECOLI|EnsemblGenome=b3941|UniProtKB=P0AEZ1	P0AEZ1	metF	PTHR45754:SF3	METHYLENETETRAHYDROFOLATE REDUCTASE	METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH)	anion binding#GO:0043168;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;catalytic activity#GO:0003824	proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;aspartate family amino acid biosynthetic process#GO:0009067;proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;tetrahydrofolate metabolic process#GO:0046653;oxoacid metabolic process#GO:0043436;tetrahydrofolate biosynthetic process#GO:0046654	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	reductase#PC00198	
ECOLI|EnsemblGenome=b4399|UniProtKB=P08401	P08401	creC	PTHR44936:SF9	SENSOR PROTEIN CREC	SENSOR PROTEIN CREC					
ECOLI|EnsemblGenome=b1611|UniProtKB=P05042	P05042	fumC	PTHR11444:SF27	ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE	FUMARATE HYDRATASE CLASS II	hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824	small molecule metabolic process#GO:0044281;cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436		lyase#PC00144	TCA cycle#P00051>Fumarase#P01271
ECOLI|EnsemblGenome=b4312|UniProtKB=P0ADH5	P0ADH5	fimB	PTHR30349:SF62	PHAGE INTEGRASE-RELATED	TYPE 1 FIMBRIAE REGULATORY PROTEIN FIMB-RELATED	catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097	nucleobase-containing compound metabolic process#GO:0006139;cell cycle process#GO:0022402;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;macromolecule metabolic process#GO:0043170;chromosome segregation#GO:0007059;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152		viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b0888|UniProtKB=P0A9P4	P0A9P4	trxB	PTHR48105:SF16	THIOREDOXIN REDUCTASE 1-RELATED-RELATED	NADPH-DEPENDENT THIOREDOXIN REDUCTASE 3	antioxidant activity#GO:0016209;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;protein-disulfide reductase activity#GO:0015035;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036	cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725		reductase#PC00198;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3101|UniProtKB=P42619	P42619	yqjF	PTHR33452:SF1	OXIDOREDUCTASE CATD-RELATED	INNER MEMBRANE PROTEIN YPHA-RELATED			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|Gene_OrderedLocusName=JW0695|UniProtKB=P75741	P75741	ybfL	PTHR30298:SF0	H REPEAT-ASSOCIATED PREDICTED TRANSPOSASE	PROTEIN YBFL-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b2708|UniProtKB=P17115	P17115	gutQ	PTHR42745:SF2	ARABINOSE 5-PHOSPHATE ISOMERASE KDSD	ARABINOSE 5-PHOSPHATE ISOMERASE GUTQ					
ECOLI|EnsemblGenome=b2208|UniProtKB=P0AAL0	P0AAL0	napF	PTHR24960:SF46	PHOTOSYSTEM I IRON-SULFUR CENTER-RELATED	FERREDOXIN-TYPE PROTEIN NAPF			cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b1638|UniProtKB=P0AFI7	P0AFI7	pdxH	PTHR10851:SF7	PYRIDOXINE-5-PHOSPHATE OXIDASE	PYRIDOXINE_PYRIDOXAMINE 5'-PHOSPHATE OXIDASE	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	organophosphate biosynthetic process#GO:0090407;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;pyridine-containing compound metabolic process#GO:0072524;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	oxidase#PC00175;oxidoreductase#PC00176	Vitamin B6 metabolism#P02787>Pyridoxamine phosphate oxidase#P03236;Pyridoxal-5-phosphate biosynthesis#P02759>Pyridoxine-5-phosphate oxidase#P03061;Pyridoxal phosphate salvage pathway#P02770>Pyridoxine-5-phosphate oxidase#P03123;Pyridoxal phosphate salvage pathway#P02770>Pyridoxamine-5-phosphate oxidase#P03120
ECOLI|EnsemblGenome=b1300|UniProtKB=P23883	P23883	puuC	PTHR11699:SF291	ALDEHYDE DEHYDROGENASE-RELATED	NADP_NAD-DEPENDENT ALDEHYDE DEHYDROGENASE PUUC	oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491	catabolic process#GO:0009056;amine metabolic process#GO:0009308;metabolic process#GO:0008152;cellular process#GO:0009987;amine catabolic process#GO:0009310		dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402
ECOLI|EnsemblGenome=b3577|UniProtKB=P37674	P37674	yiaM	PTHR35011:SF2	2,3-DIKETO-L-GULONATE TRAP TRANSPORTER SMALL PERMEASE PROTEIN YIAM	2,3-DIKETO-L-GULONATE TRAP TRANSPORTER SMALL PERMEASE PROTEIN YIAM	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	establishment of localization#GO:0051234;localization#GO:0051179;dicarboxylic acid transport#GO:0006835;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b2214|UniProtKB=P0AB85	P0AB85	apbE	PTHR30040:SF2	THIAMINE BIOSYNTHESIS LIPOPROTEIN APBE	FAD:PROTEIN FMN TRANSFERASE	transferase activity#GO:0016740;catalytic activity#GO:0003824				
ECOLI|EnsemblGenome=b4155|UniProtKB=P0A8N7	P0A8N7	epmA	PTHR42918:SF6	LYSYL-TRNA SYNTHETASE	ELONGATION FACTOR P--(R)-BETA-LYSINE LIGASE	catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488	nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263	
ECOLI|EnsemblGenome=b0265|UniProtKB=P0CF08	P0CF08	insA2	PTHR47923:SF1	INSERTION ELEMENT IS1 1 PROTEIN INSA-RELATED	INSERTION ELEMENT IS1 1 PROTEIN INSA-RELATED		nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259			
ECOLI|EnsemblGenome=b1378|UniProtKB=P52647	P52647	ydbK	PTHR32154:SF0	PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED	PYRUVATE:FLAVODOXIN OXIDOREDUCTASE	catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491	response to oxidative stress#GO:0006979;response to stimulus#GO:0050896;response to stress#GO:0006950		oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2806|UniProtKB=P0ADR6	P0ADR6	rlmM	PTHR37524:SF2	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE M	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE M	S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;O-methyltransferase activity#GO:0008171;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173	primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170		RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b1186|UniProtKB=P0AFA7	P0AFA7	nhaB	PTHR43302:SF1	TRANSPORTER ARSB-RELATED	NA(+)_H(+) ANTIPORTER NHAB	metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	primary active transporter#PC00068;transporter#PC00227	
ECOLI|EnsemblGenome=b3583|UniProtKB=P37680	P37680	sgbE	PTHR22789:SF8	FUCULOSE PHOSPHATE ALDOLASE	L-RIBULOSE-5-PHOSPHATE 4-EPIMERASE SGBE	lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832;isomerase activity#GO:0016853;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;carbon-carbon lyase activity#GO:0016830	cellular process#GO:0009987;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	lyase#PC00144;aldolase#PC00044	Ascorbate degradation#P02729>L-ribulose-5-phosphate-4-epimerase#P02851
ECOLI|EnsemblGenome=b2115|UniProtKB=P33345	P33345	yehF	PTHR30634:SF13	OUTER MEMBRANE LOLAB LIPOPROTEIN INSERTION APPARATUS	PROTEIN YEHF				transporter#PC00227	
ECOLI|EnsemblGenome=b3297|UniProtKB=P0A7R9	P0A7R9	rpsK	PTHR11759:SF77	40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11	SMALL RIBOSOMAL SUBUNIT PROTEIN US11	structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735	translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307	ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737	translational protein#PC00263;ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b0619|UniProtKB=P77510	P77510	dpiB	PTHR43047:SF62	TWO-COMPONENT HISTIDINE PROTEIN KINASE	SENSOR HISTIDINE KINASE DPIB	phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;catalytic activity#GO:0003824;phosphorelay sensor kinase activity#GO:0000155;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein histidine kinase activity#GO:0004673;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672	signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;phosphorelay signal transduction system#GO:0000160;intracellular signal transduction#GO:0035556;cell communication#GO:0007154	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	histidine kinase receptor of two-component system#PC00265	
ECOLI|EnsemblGenome=b2781|UniProtKB=P0AEY3	P0AEY3	mazG	PTHR30522:SF0	NUCLEOSIDE TRIPHOSPHATE PYROPHOSPHOHYDROLASE	NUCLEOSIDE TRIPHOSPHATE PYROPHOSPHOHYDROLASE	hydrolase activity#GO:0016787;nucleoside triphosphate diphosphatase activity#GO:0047429;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817	purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleotide metabolic process#GO:0006163		hydrolase#PC00121	
ECOLI|EnsemblGenome=b1753|UniProtKB=P76222	P76222	ynjA	PTHR34846:SF10	4-CARBOXYMUCONOLACTONE DECARBOXYLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G11590)	BLL6975 PROTEIN				decarboxylase#PC00089	
ECOLI|EnsemblGenome=b1246|UniProtKB=P76027	P76027	oppD	PTHR43297:SF7	OLIGOPEPTIDE TRANSPORT ATP-BINDING PROTEIN APPD	D,D-DIPEPTIDE TRANSPORT ATP-BINDING PROTEIN DDPD-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate derivative transmembrane transporter activity#GO:1901505			transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0164|UniProtKB=P37049	P37049	yaeI	PTHR31302:SF31	TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN-RELATED	PHOSPHODIESTERASE YAEI	hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787	biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;carbohydrate derivative biosynthetic process#GO:1901137;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;lipid A biosynthetic process#GO:0009245;liposaccharide metabolic process#GO:1903509;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407			
ECOLI|EnsemblGenome=b0373|UniProtKB=P0CF67	P0CF67	insE2	PTHR33215:SF6	PROTEIN DISTAL ANTENNA	TRANSPOSASE INSE FOR INSERTION SEQUENCE IS3A-RELATED					
ECOLI|EnsemblGenome=b0688|UniProtKB=P36938	P36938	pgm	PTHR22573:SF57	PHOSPHOHEXOMUTASE FAMILY MEMBER	PHOSPHOGLUCOMUTASE	isomerase activity#GO:0016853;intramolecular phosphotransferase activity#GO:0016868;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824	cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	mutase#PC00160;isomerase#PC00135;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3556|UniProtKB=P0A9X9	P0A9X9	cspA	PTHR11544:SF138	COLD SHOCK DOMAIN CONTAINING PROTEINS	COLD SHOCK PROTEIN CSPA-RELATED					
ECOLI|EnsemblGenome=b0162|UniProtKB=P37047	P37047	cdaR	PTHR33744:SF15	CARBOHYDRATE DIACID REGULATOR	CARBOHYDRATE DIACID REGULATOR	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789			
ECOLI|EnsemblGenome=b2109|UniProtKB=P33341	P33341	yehB	PTHR30451:SF3	OUTER MEMBRANE USHER PROTEIN	OUTER MEMBRANE USHER PROTEIN HTRE-RELATED	passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;wide pore channel activity#GO:0022829;channel activity#GO:0015267	cell adhesion#GO:0007155;cellular process#GO:0009987	cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane#GO:0019867;extracellular region#GO:0005576;cell outer membrane#GO:0009279;membrane#GO:0016020;external encapsulating structure#GO:0030312		
ECOLI|EnsemblGenome=b0839|UniProtKB=P08506	P08506	dacC	PTHR21581:SF6	D-ALANYL-D-ALANINE CARBOXYPEPTIDASE	D-ALANYL-D-ALANINE CARBOXYPEPTIDASE DACC				protease#PC00190;serine protease#PC00203	
ECOLI|EnsemblGenome=b0336|UniProtKB=P0AA82	P0AA82	codB	PTHR30569:SF0	CYTOSINE TRANSPORTER CODB	CYTOSINE PERMEASE	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;nucleobase transmembrane transporter activity#GO:0015205	establishment of localization#GO:0051234;localization#GO:0051179;nitrogen compound transport#GO:0071705;nucleobase transport#GO:0015851;transport#GO:0006810;pyrimidine nucleobase transport#GO:0015855	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b2425|UniProtKB=P16700	P16700	cysP	PTHR30368:SF1	SULFATE-BINDING PROTEIN	THIOSULFATE-BINDING PROTEIN	ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488	sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313;extracellular region#GO:0005576;periplasmic space#GO:0042597		
ECOLI|EnsemblGenome=b1990|UniProtKB=P39176	P39176	erfK	PTHR30582:SF24	L,D-TRANSPEPTIDASE	L,D-TRANSPEPTIDASE ERFK_SRFK-RELATED	peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236	cellular component organization or biogenesis#GO:0071840;glycosaminoglycan biosynthetic process#GO:0006024;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;peptidoglycan metabolic process#GO:0000270;peptidoglycan-based cell wall biogenesis#GO:0009273;biosynthetic process#GO:0009058;cell wall organization or biogenesis#GO:0071554;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;cell wall macromolecule biosynthetic process#GO:0044038;cell wall macromolecule metabolic process#GO:0044036;cell wall biogenesis#GO:0042546;aminoglycan metabolic process#GO:0006022;peptidoglycan biosynthetic process#GO:0009252;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan metabolic process#GO:0030203	extracellular region#GO:0005576;cellular anatomical structure#GO:0110165	protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260	
ECOLI|EnsemblGenome=b3458|UniProtKB=P04816	P04816	livK	PTHR47151:SF3	LEU/ILE/VAL-BINDING ABC TRANSPORTER SUBUNIT	LEUCINE-SPECIFIC-BINDING PROTEIN		L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;L-leucine transport#GO:0015820;amino acid transport#GO:0006865;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;branched-chain amino acid transport#GO:0015803;localization#GO:0051179;neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234	extracellular region#GO:0005576;periplasmic space#GO:0042597;cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227	
ECOLI|EnsemblGenome=b1207|UniProtKB=P0A717	P0A717	prs	PTHR10210:SF41	RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER	RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 5, CHLOROPLASTIC	transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740	purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058	cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494	metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172	
ECOLI|EnsemblGenome=b4240|UniProtKB=P36672	P36672	treB	PTHR30175:SF4	PHOSPHOTRANSFERASE SYSTEM TRANSPORT PROTEIN	PTS SYSTEM TREHALOSE-SPECIFIC EIIBC COMPONENT	protein-phosphocysteine-sugar phosphotransferase activity#GO:0090563;phosphotransferase activity, alcohol group as acceptor#GO:0016773;carbohydrate transmembrane transporter activity#GO:0015144;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804	transport#GO:0006810;carbohydrate transport#GO:0008643;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;transmembrane transport#GO:0055085;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b2954|UniProtKB=P52061	P52061	rdgB	PTHR11067:SF10	INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN	DITP_XTP PYROPHOSPHATASE	hydrolase activity#GO:0016787;nucleoside triphosphate diphosphatase activity#GO:0047429;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817	cellular process#GO:0009987;purine nucleoside triphosphate metabolic process#GO:0009144;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate catabolic process#GO:0046434	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	nucleotide phosphatase#PC00173	Thiamin metabolism#P02780>Nucleoside triphosphatase#P03180
ECOLI|EnsemblGenome=b1149|UniProtKB=P75978	P75978	ymfN	PTHR41287:SF1	PROTEIN YMFN	PROTEIN YMFN					
ECOLI|EnsemblGenome=b2874|UniProtKB=Q46807	Q46807	yqeA	PTHR30409:SF1	CARBAMATE KINASE	CARBAMATE KINASE-LIKE PROTEIN YAHI-RELATED	transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	transferase#PC00220;kinase#PC00137	
ECOLI|EnsemblGenome=b0475|UniProtKB=P23871	P23871	hemH	PTHR11108:SF11	FERROCHELATASE	FERROCHELATASE	catalytic activity#GO:0003824;lyase activity#GO:0016829	porphyrin-containing compound biosynthetic process#GO:0006779;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;cellular process#GO:0009987		lyase#PC00144	Heme biosynthesis#P02746>Ferrochelatase#P02972
ECOLI|EnsemblGenome=b0129|UniProtKB=P36881	P36881	yadI	PTHR33799:SF1	PTS PERMEASE-RELATED-RELATED	PTS SYSTEM MANNOSE-SPECIFIC EIIAB COMPONENT-RELATED	active transmembrane transporter activity#GO:0022804;transferase activity#GO:0016740;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;carbohydrate transmembrane transporter activity#GO:0015144	cellular process#GO:0009987;import across plasma membrane#GO:0098739;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643;transport#GO:0006810;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;transmembrane transport#GO:0055085	membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0750|UniProtKB=P11458	P11458	nadA	PTHR30573:SF1	QUINOLINATE SYNTHETASE A	QUINOLINATE SYNTHASE	transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824	nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;pyridine-containing compound metabolic process#GO:0072524;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;oxoacid metabolic process#GO:0043436;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	transferase#PC00220	
ECOLI|EnsemblGenome=b1814|UniProtKB=P16095	P16095	sdaA	PTHR30182:SF1	L-SERINE DEHYDRATASE	L-SERINE DEHYDRATASE 1	catalytic activity#GO:0003824;lyase activity#GO:0016829	oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238		lyase#PC00144;dehydratase#PC00091	
ECOLI|EnsemblGenome=b0151|UniProtKB=P07821	P07821	fhuC	PTHR42771:SF14	IRON(3+)-HYDROXAMATE IMPORT ATP-BINDING PROTEIN FHUC	IRON(3+)-HYDROXAMATE IMPORT ATP-BINDING PROTEIN FHUC	siderophore-iron transmembrane transporter activity#GO:0015343;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	localization#GO:0051179;monoatomic cation transport#GO:0006812;homeostatic process#GO:0042592;metal ion transport#GO:0030001;cellular response to stimulus#GO:0051716;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;response to metal ion#GO:0010038;siderophore-iron import into cell#GO:0033214;siderophore-dependent iron import pathway#GO:0180060;cellular localization#GO:0051641;monoatomic ion transport#GO:0006811;cellular response to chemical stimulus#GO:0070887;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;iron ion transport#GO:0006826;intracellular iron ion homeostasis#GO:0006879;response to stimulus#GO:0050896;iron import into cell#GO:0033212;intracellular monoatomic ion homeostasis#GO:0006873;import into cell#GO:0098657;response to iron ion#GO:0010039;iron coordination entity transport#GO:1901678;chemical homeostasis#GO:0048878;response to chemical#GO:0042221;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization in cell#GO:0051649	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|Gene_OrderedLocusName=JW1503|UniProtKB=P32051	P32051	ydeK	PTHR35037:SF3	C-TERMINAL REGION OF AIDA-LIKE PROTEIN	PROTEASE HOMOLOGUE-PUTATIVE SECRETED SERINE PROTEASE-RELATED					
ECOLI|EnsemblGenome=b3857|UniProtKB=P32173	P32173	mobA	PTHR19136:SF87	MOLYBDENUM COFACTOR GUANYLYLTRANSFERASE	MOLYBDENUM COFACTOR GUANYLYLTRANSFERASE	nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772	cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;macromolecule metabolic process#GO:0043170;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;nucleotide metabolic process#GO:0009117		transferase#PC00220	
ECOLI|EnsemblGenome=b0915|UniProtKB=P27300	P27300	lpxK	PTHR42724:SF2	TETRAACYLDISACCHARIDE 4'-KINASE	TETRAACYLDISACCHARIDE 4'-KINASE	phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772	carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;oligosaccharide metabolic process#GO:0009311;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;lipopolysaccharide core region biosynthetic process#GO:0009244;lipopolysaccharide biosynthetic process#GO:0009103;carbohydrate metabolic process#GO:0005975;phospholipid metabolic process#GO:0006644;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;polysaccharide metabolic process#GO:0005976;liposaccharide metabolic process#GO:1903509;lipid A biosynthetic process#GO:0009245;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;oligosaccharide biosynthetic process#GO:0009312;organophosphate biosynthetic process#GO:0090407;lipopolysaccharide metabolic process#GO:0008653;glycolipid biosynthetic process#GO:0009247;polysaccharide biosynthetic process#GO:0000271	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transferase#PC00220;kinase#PC00137	
ECOLI|EnsemblGenome=b2389|UniProtKB=P67729	P67729	yfeO	PTHR43427:SF9	CHLORIDE CHANNEL PROTEIN CLC-E	ION-TRANSPORT PROTEIN YFEO-RELATED		cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	ion channel#PC00133	
ECOLI|EnsemblGenome=b1698|UniProtKB=P77378	P77378	ydiR	PTHR43153:SF13	ELECTRON TRANSFER FLAVOPROTEIN ALPHA	ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT YDIR-RELATED	heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265	primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258		oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1524|UniProtKB=P0A6W0	P0A6W0	glsA2	PTHR12544:SF29	GLUTAMINASE	GLUTAMINASE 2	hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824	oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056		hydrolase#PC00121	
ECOLI|EnsemblGenome=b2456|UniProtKB=P0AEJ8	P0AEJ8	eutN	PTHR36539:SF1	ETHANOLAMINE UTILIZATION PROTEIN EUTN	BACTERIAL MICROCOMPARTMENT SHELL VERTEX PROTEIN EUTN					
ECOLI|EnsemblGenome=b3406|UniProtKB=P30128	P30128	greB	PTHR30437:SF6	TRANSCRIPTION ELONGATION FACTOR GREA	TRANSCRIPTION ELONGATION FACTOR GREB		metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;DNA-templated transcription elongation#GO:0006354;nucleic acid metabolic process#GO:0090304;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351			
ECOLI|EnsemblGenome=b4174|UniProtKB=P0ABC7	P0ABC7	hflK	PTHR43327:SF2	STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL	MODULATOR OF FTSH PROTEASE HFLK				transporter#PC00227	
ECOLI|EnsemblGenome=b1546|UniProtKB=P76155	P76155	tfaQ	PTHR34413:SF2	PROPHAGE TAIL FIBER ASSEMBLY PROTEIN HOMOLOG TFAE-RELATED-RELATED	PROPHAGE TAIL FIBER ASSEMBLY PROTEIN HOMOLOG TFAE-RELATED				chaperone#PC00072	
ECOLI|EnsemblGenome=b0932|UniProtKB=P04825	P04825	pepN	PTHR46322:SF1	PUROMYCIN-SENSITIVE AMINOPEPTIDASE	PUROMYCIN-SENSITIVE AMINOPEPTIDASE					
ECOLI|EnsemblGenome=b3009|UniProtKB=P0AA60	P0AA60	yghB	PTHR30353:SF10	INNER MEMBRANE PROTEIN DEDA-RELATED	INNER MEMBRANE PROTEIN YGHB	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	transport#GO:0006810;cytokinesis#GO:0000910;FtsZ-dependent cytokinesis#GO:0043093;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cell division#GO:0051301;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;reproductive process#GO:0022414;reproductive process in single-celled organism#GO:0022413	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b1925|UniProtKB=P26608	P26608	fliS	PTHR34773:SF1	FLAGELLAR SECRETION CHAPERONE FLIS	FLAGELLAR SECRETION CHAPERONE FLIS		bacterial-type flagellum-dependent cell motility#GO:0071973;cell motility#GO:0048870;cilium or flagellum-dependent cell motility#GO:0001539;cellular process#GO:0009987;archaeal or bacterial-type flagellum-dependent cell motility#GO:0097588			
ECOLI|EnsemblGenome=b1018|UniProtKB=P0AB24	P0AB24	efeO	PTHR39192:SF1	IRON UPTAKE SYSTEM COMPONENT EFEO	IRON UPTAKE SYSTEM COMPONENT EFEO					
ECOLI|EnsemblGenome=b3546|UniProtKB=P37661	P37661	eptB	PTHR30443:SF3	INNER MEMBRANE PROTEIN	KDO(2)-LIPID A PHOSPHOETHANOLAMINE 7''-TRANSFERASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;phosphotransferase activity, phosphate group as acceptor#GO:0016776	organophosphate biosynthetic process#GO:0090407;oligosaccharide biosynthetic process#GO:0009312;lipopolysaccharide metabolic process#GO:0008653;glycolipid biosynthetic process#GO:0009247;polysaccharide biosynthetic process#GO:0000271;lipopolysaccharide core region biosynthetic process#GO:0009244;lipopolysaccharide biosynthetic process#GO:0009103;phospholipid metabolic process#GO:0006644;carbohydrate metabolic process#GO:0005975;phospholipid biosynthetic process#GO:0008654;polysaccharide metabolic process#GO:0005976;glycolipid metabolic process#GO:0006664;lipid A biosynthetic process#GO:0009245;liposaccharide metabolic process#GO:1903509;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;oligosaccharide metabolic process#GO:0009311;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b3519|UniProtKB=P62601	P62601	treF	PTHR23403:SF8	TREHALASE	CYTOPLASMIC TREHALASE	hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824	carbohydrate catabolic process#GO:0016052;oligosaccharide metabolic process#GO:0009311;metabolic process#GO:0008152;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;cellular process#GO:0009987			
ECOLI|EnsemblGenome=b1621|UniProtKB=P19642	P19642	malX	PTHR30009:SF25	CYTOCHROME C-TYPE SYNTHESIS PROTEIN AND PTS TRANSMEMBRANE COMPONENT	PTS SYSTEM GLUCOSE-SPECIFIC EIICB COMPONENT-RELATED	transferase activity, transferring phosphorus-containing groups#GO:0016772;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;transferase activity#GO:0016740;active transmembrane transporter activity#GO:0022804;protein-phosphocysteine-sugar phosphotransferase activity#GO:0090563;carbohydrate transmembrane transporter activity#GO:0015144;phosphotransferase activity, alcohol group as acceptor#GO:0016773	import across plasma membrane#GO:0098739;carbohydrate transmembrane transport#GO:0034219;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;localization#GO:0051179;transmembrane transport#GO:0055085;import into cell#GO:0098657;establishment of localization#GO:0051234;carbohydrate transport#GO:0008643;transport#GO:0006810	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b0502|UniProtKB=P77688	P77688	ylbG	PTHR42648:SF11	TRANSPOSASE, PUTATIVE-RELATED	TRANSPOSON TY4-P GAG-POL POLYPROTEIN				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b1834|UniProtKB=P76272	P76272	letB	PTHR30462:SF0	INTERMEMBRANE TRANSPORT PROTEIN PQIB-RELATED	LIPOPHILIC ENVELOPE-SPANNING TUNNEL PROTEIN B		cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b4461|UniProtKB=P37908	P37908	yfjD	PTHR22777:SF32	HEMOLYSIN-RELATED	UPF0053 INNER MEMBRANE PROTEIN YFJD			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b1930|UniProtKB=P0AA31	P0AA31	yedF	PTHR33279:SF6	SULFUR CARRIER PROTEIN YEDF-RELATED	SULFUR CARRIER PROTEIN TSUB-RELATED				transfer/carrier protein#PC00219	
ECOLI|EnsemblGenome=b3740|UniProtKB=P0A6U5	P0A6U5	rsmG	PTHR31760:SF0	S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN	RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G	RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;rRNA (guanine) methyltransferase activity#GO:0016435;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a rRNA#GO:0140102;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	methyltransferase#PC00155	
ECOLI|EnsemblGenome=b3124|UniProtKB=P23524	P23524	garK	PTHR21599:SF7	GLYCERATE KINASE	GLYCERATE 2-KINASE	transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773			kinase#PC00137	Allantoin degradation#P02725>Glycerate kinase II#P02817
ECOLI|EnsemblGenome=b2910|UniProtKB=P0ADS2	P0ADS2	zapA	PTHR34981:SF1	CELL DIVISION PROTEIN ZAPA	CELL DIVISION PROTEIN ZAPA		cytokinetic process#GO:0032506;organelle assembly#GO:0070925;cytokinesis#GO:0000910;septin ring organization#GO:0031106;protein-containing complex assembly#GO:0065003;cell division#GO:0051301;cell cycle process#GO:0022402;cell septum assembly#GO:0090529;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;reproductive process#GO:0022414;reproductive process in single-celled organism#GO:0022413;FtsZ-dependent cytokinesis#GO:0043093;septin cytoskeleton organization#GO:0032185;division septum assembly#GO:0000917;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cell septum#GO:0030428;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cell division site#GO:0032153		
ECOLI|EnsemblGenome=b3253|UniProtKB=P26646	P26646	acuI	PTHR43677:SF1	SHORT-CHAIN DEHYDROGENASE/REDUCTASE	ACRYLYL-COA REDUCTASE ACUI-RELATED	oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2733|UniProtKB=P23909	P23909	mutS	PTHR11361:SF159	DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER	DNA MISMATCH REPAIR PROTEIN MUTS	nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677	metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular process#GO:0009987;mismatch repair#GO:0006298;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b1948|UniProtKB=P0AC05	P0AC05	fliP	PTHR30587:SF0	FLAGELLAR BIOSYNTHETIC PROTEIN FLIP	FLAGELLAR BIOSYNTHETIC PROTEIN FLIP		cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;bacterial-type flagellum-dependent cell motility#GO:0071973;cellular component organization or biogenesis#GO:0071840;bacterial-type flagellum assembly#GO:0044780;archaeal or bacterial-type flagellum-dependent cell motility#GO:0097588;cell motility#GO:0048870;cell projection organization#GO:0030030;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;bacterial-type flagellum-dependent swarming motility#GO:0071978;organelle assembly#GO:0070925;cilium or flagellum-dependent cell motility#GO:0001539	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b0715|UniProtKB=P75747	P75747	abrB	PTHR38457:SF1	REGULATOR ABRB-RELATED	REGULATOR ABRB-RELATED			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2482|UniProtKB=P23482	P23482	hyfB	PTHR42682:SF3	HYDROGENASE-4 COMPONENT F	FORMATE HYDROGENLYASE SUBUNIT 3-RELATED		anaerobic electron transport chain#GO:0019645;anaerobic respiration#GO:0009061;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;electron transport chain#GO:0022900;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436	catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991	oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1263|UniProtKB=P00904	P00904	trpGD	PTHR43418:SF2	MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN-RELATED	BIFUNCTIONAL PROTEIN TRPGD	pentosyltransferase activity#GO:0016763;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;lyase activity#GO:0016829	proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;antibiotic biosynthetic process#GO:0017000;cellular process#GO:0009987;amine metabolic process#GO:0009308;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;indole-containing compound metabolic process#GO:0042430;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;aromatic amino acid biosynthetic process#GO:0009073			
ECOLI|EnsemblGenome=b2219|UniProtKB=Q06067	Q06067	atoS	PTHR43065:SF54	SENSOR HISTIDINE KINASE	SENSOR HISTIDINE KINASE ZRAS-RELATED			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	histidine kinase receptor of two-component system#PC00265	
ECOLI|EnsemblGenome=b1174|UniProtKB=P0A734	P0A734	minE	PTHR33404:SF10	CELL DIVISION TOPOLOGICAL SPECIFICITY FACTOR HOMOLOG, CHLOROPLASTIC	CELL DIVISION TOPOLOGICAL SPECIFICITY FACTOR		cytokinesis#GO:0000910;cytokinetic process#GO:0032506;cellular component organization or biogenesis#GO:0071840;division septum assembly#GO:0000917;cellular component biogenesis#GO:0044085;cell septum assembly#GO:0090529;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle process#GO:0022402;cell division#GO:0051301;cellular component assembly#GO:0022607	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b4327|UniProtKB=P39376	P39376	yjiE	PTHR30126:SF2	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR YJIE	double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468		helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b2101|UniProtKB=P0ACM5	P0ACM5	ggaR	PTHR44846:SF1	MANNOSYL-D-GLYCERATE TRANSPORT/METABOLISM SYSTEM REPRESSOR MNGR-RELATED	HTH-TYPE TRANSCRIPTIONAL REGULATOR GGAR-RELATED		regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519		helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b2682|UniProtKB=P76630	P76630	ygaZ	PTHR34979:SF1	INNER MEMBRANE PROTEIN YGAZ	INNER MEMBRANE PROTEIN YGAZ		cellular process#GO:0009987;L-amino acid transport#GO:0015807;L-alpha-amino acid transmembrane transport#GO:1902475;nitrogen compound transport#GO:0071705;carboxylic acid transmembrane transport#GO:1905039;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;branched-chain amino acid transport#GO:0015803;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085			
ECOLI|EnsemblGenome=b2437|UniProtKB=P36547	P36547	eutR	PTHR46796:SF12	HTH-TYPE TRANSCRIPTIONAL ACTIVATOR RHAS-RELATED	HTH-TYPE DNA-BINDING TRANSCRIPTIONAL ACTIVATOR EUTR	transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468		helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b4477|UniProtKB=Q6BF16	Q6BF16	dgoA	PTHR30246:SF3	2-KETO-3-DEOXY-6-PHOSPHOGLUCONATE ALDOLASE	2-DEHYDRO-3-DEOXY-6-PHOSPHOGALACTONATE ALDOLASE	aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824	carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238		lyase#PC00144;aldolase#PC00044	
ECOLI|EnsemblGenome=b3301|UniProtKB=P02413	P02413	rplO	PTHR12934:SF11	50S RIBOSOMAL PROTEIN L15	LARGE RIBOSOMAL SUBUNIT PROTEIN UL15C	structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198			ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b3708|UniProtKB=P0A853	P0A853	tnaA	PTHR32325:SF4	BETA-ELIMINATING LYASE-LIKE PROTEIN-RELATED	TRYPTOPHANASE	catalytic activity#GO:0003824;lyase activity#GO:0016829			lyase#PC00144	
ECOLI|EnsemblGenome=b3203|UniProtKB=P0AFX0	P0AFX0	hpf	PTHR33231:SF4	30S RIBOSOMAL PROTEIN	RIBOSOME HIBERNATION PROMOTING FACTOR	translation regulator activity#GO:0045182	regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of translation#GO:0017148;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b1684|UniProtKB=P77667	P77667	sufA	PTHR10072:SF47	IRON-SULFUR CLUSTER ASSEMBLY PROTEIN	IRON-SULFUR CLUSTER ASSEMBLY PROTEIN SUFA	iron-sulfur cluster binding#GO:0051536;small molecule binding#GO:0036094;binding#GO:0005488	cellular component biogenesis#GO:0044085;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component assembly#GO:0022607;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;iron-sulfur cluster assembly#GO:0016226;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein metabolic process#GO:0019538	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	chaperone#PC00072	
ECOLI|EnsemblGenome=b3418|UniProtKB=P06993	P06993	malT	PTHR44688:SF31	DNA-BINDING TRANSCRIPTIONAL ACTIVATOR DEVR_DOSR	HTH-TYPE TRANSCRIPTIONAL REGULATOR MALT				helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b3912|UniProtKB=P0AE88	P0AE88	cpxR	PTHR48111:SF39	REGULATOR OF RPOS	TRANSCRIPTIONAL REGULATORY PROTEIN CPXR	double-stranded DNA binding#GO:0003690;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993	winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b2058|UniProtKB=P0ACC9	P0ACC9	wcaB	PTHR42811:SF5	SERINE ACETYLTRANSFERASE	SERINE ACETYLTRANSFERASE-RELATED	acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740	biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	acetyltransferase#PC00038;transferase#PC00220	Cysteine biosynthesis#P02737>Serine acetyltransferase#P02888
ECOLI|EnsemblGenome=b0827|UniProtKB=P12281	P12281	moeA	PTHR10192:SF5	MOLYBDOPTERIN BIOSYNTHESIS PROTEIN	GEPHYRIN	catalytic activity#GO:0003824;transferase activity#GO:0016740	biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;metabolic process#GO:0008152	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b0770|UniProtKB=P75763	P75763	ybhI	PTHR42826:SF13	DICARBOXYLATE TRANSPORTER 2.1, CHLOROPLASTIC	INNER MEMBRANE PROTEIN YBHI				primary active transporter#PC00068;transporter#PC00227	
ECOLI|EnsemblGenome=b0949|UniProtKB=P43672	P43672	uup	PTHR19211:SF69	ATP-BINDING TRANSPORT PROTEIN-RELATED	ATP-BINDING PROTEIN UUP	anion binding#GO:0043168;ATP binding#GO:0005524;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367			translation elongation factor#PC00222	
ECOLI|EnsemblGenome=b1756|UniProtKB=P76909	P76909	ynjD	PTHR42781:SF10	SPERMIDINE/PUTRESCINE IMPORT ATP-BINDING PROTEIN POTA	SPERMIDINE_PUTRESCINE IMPORT ATP-BINDING PROTEIN POTA	transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;polyamine transmembrane transporter activity#GO:0015203		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227	
ECOLI|EnsemblGenome=b0734|UniProtKB=P0ABK2	P0ABK2	cydB	PTHR43141:SF5	CYTOCHROME BD2 SUBUNIT II	CYTOCHROME BD-I UBIQUINOL OXIDASE SUBUNIT 2	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on diphenols and related substances as donors#GO:0016679;catalytic activity#GO:0003824	generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900	catalytic complex#GO:1902494;cytochrome complex#GO:0070069;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3454|UniProtKB=P22731	P22731	livF	PTHR43820:SF4	HIGH-AFFINITY BRANCHED-CHAIN AMINO ACID TRANSPORT ATP-BINDING PROTEIN LIVF	HIGH-AFFINITY BRANCHED-CHAIN AMINO ACID TRANSPORT ATP-BINDING PROTEIN LIVF	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;branched-chain amino acid transmembrane transporter activity#GO:0015658	nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;organic acid transport#GO:0015849;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179		ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b1991|UniProtKB=P36562	P36562	cobT	PTHR43463:SF1	NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE	NICOTINATE-NUCLEOTIDE--DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE				transferase#PC00220;nucleotidyltransferase#PC00174	
ECOLI|EnsemblGenome=b3218|UniProtKB=P0CE57	P0CE57	insH10	PTHR35604:SF2	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640	primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b2842|UniProtKB=P37769	P37769	kduD	PTHR42760:SF5	SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER	2-DEHYDRO-3-DEOXY-D-GLUCONATE 5-DEHYDROGENASE	oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2750|UniProtKB=P0A6J1	P0A6J1	cysC	PTHR11055:SF78	BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE	ADENYLYL-SULFATE KINASE	phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824				Sulfate assimilation#P02778>Adenylylsulfate kinase#P03164
ECOLI|EnsemblGenome=b0436|UniProtKB=P0A850	P0A850	tig	PTHR30560:SF3	TRIGGER FACTOR CHAPERONE AND PEPTIDYL-PROLYL CIS/TRANS ISOMERASE	TRIGGER FACTOR-LIKE PROTEIN TIG, CHLOROPLASTIC	ribonucleoprotein complex binding#GO:0043021;cis-trans isomerase activity#GO:0016859;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity#GO:0003824	metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058		chaperone#PC00072	
ECOLI|EnsemblGenome=b2982|UniProtKB=P0CE56	P0CE56	insH9	PTHR35604:SF2	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824	cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b2182|UniProtKB=P28246	P28246	bcr	PTHR23502:SF197	MAJOR FACILITATOR SUPERFAMILY	BICYCLOMYCIN RESISTANCE PROTEIN	monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873	response to stimulus#GO:0050896;response to chemical#GO:0042221;response to toxic substance#GO:0009636;detoxification#GO:0098754;export from cell#GO:0140352;cellular process#GO:0009987;xenobiotic detoxification by transmembrane export across the plasma membrane#GO:1990961;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;xenobiotic transport#GO:0042908;transport#GO:0006810	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b3225|UniProtKB=P0A6L4	P0A6L4	nanA	PTHR42849:SF1	N-ACETYLNEURAMINATE LYASE	N-ACETYLNEURAMINATE LYASE	lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824	amino sugar catabolic process#GO:0046348;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino sugar metabolic process#GO:0006040;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carboxylic acid catabolic process#GO:0046395	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	lyase#PC00144	N-acetylglucosamine metabolism#P02756>N-acetylneuraminate lyase#P03040
ECOLI|EnsemblGenome=b1908|UniProtKB=P0AD05	P0AD05	yecA	PTHR33747:SF9	UPF0225 PROTEIN SCO1677	METAL-BINDING PROTEIN					
ECOLI|EnsemblGenome=b1189|UniProtKB=P0A6J5	P0A6J5	dadA	PTHR13847:SF280	SARCOSINE DEHYDROGENASE-RELATED	D-AMINO ACID DEHYDROGENASE	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b0179|UniProtKB=P21645	P21645	lpxD	PTHR43378:SF2	UDP-3-O-ACYLGLUCOSAMINE N-ACYLTRANSFERASE	UDP-3-O-(3-HYDROXYMYRISTOYL)GLUCOSAMINE N-ACYLTRANSFERASE	acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740			metabolite interconversion enzyme#PC00262;acyltransferase#PC00042	
ECOLI|EnsemblGenome=b3741|UniProtKB=P0A6U3	P0A6U3	mnmG	PTHR11806:SF3	GLUCOSE INHIBITED DIVISION PROTEIN A	TRNA URIDINE 5-CARBOXYMETHYLAMINOMETHYL MODIFICATION ENZYME MNMG	catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640	nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;sulfurtransferase complex#GO:1990228;cytoplasm#GO:0005737;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494		
ECOLI|EnsemblGenome=b0148|UniProtKB=P37024	P37024	hrpB	PTHR43519:SF1	ATP-DEPENDENT RNA HELICASE HRPB	ATP-DEPENDENT RNA HELICASE HRPB	ribonucleoside triphosphate phosphatase activity#GO:0017111;single-stranded RNA binding#GO:0003727;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818			RNA helicase#PC00032;RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b2873|UniProtKB=Q46806	Q46806	hyuA	PTHR11647:SF97	HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER	D-PHENYLHYDANTOINASE	hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;catalytic activity#GO:0003824		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	hydrolase#PC00121	Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125
ECOLI|EnsemblGenome=b1040|UniProtKB=P52106	P52106	csgD	PTHR44688:SF28	DNA-BINDING TRANSCRIPTIONAL ACTIVATOR DEVR_DOSR	CSGBAC OPERON TRANSCRIPTIONAL REGULATORY PROTEIN				gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b0173|UniProtKB=P45568	P45568	dxr	PTHR30525:SF8	1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE	1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE	oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824		protein-containing complex#GO:0032991	oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3599|UniProtKB=P00550	P00550	mtlA	PTHR30181:SF2	MANNITOL PERMEASE IIC COMPONENT	PTS SYSTEM MANNITOL-SPECIFIC EIICBA COMPONENT	protein-phosphocysteine-sugar phosphotransferase activity#GO:0090563;carbohydrate transmembrane transporter activity#GO:0015144;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;active transmembrane transporter activity#GO:0022804	carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;import into cell#GO:0098657;localization#GO:0051179;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;organic hydroxy compound transport#GO:0015850;transport#GO:0006810;carbohydrate transport#GO:0008643	cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351		
ECOLI|EnsemblGenome=b3828|UniProtKB=P0A9F9	P0A9F9	metR	PTHR30126:SF25	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR METR	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690	biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355		gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b0505|UniProtKB=P77731	P77731	allA	PTHR21221:SF2	UREIDOGLYCOLATE HYDROLASE	UREIDOGLYCOLATE LYASE	catalytic activity#GO:0003824;lyase activity#GO:0016829			hydrolase#PC00121;metabolite interconversion enzyme#PC00262	Allantoin degradation#P02725>Ureidoglycolate hydrolase#P02818
ECOLI|EnsemblGenome=b2882|UniProtKB=P67444	P67444	xanQ	PTHR42810:SF5	PURINE PERMEASE C1399.01C-RELATED	XANTHINE PERMEASE XANQ	nucleobase transmembrane transporter activity#GO:0015205;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;nucleobase transport#GO:0015851;nitrogen compound transport#GO:0071705	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b1251|UniProtKB=P0AB55	P0AB55	yciI	PTHR33606:SF3	PROTEIN YCII	PROTEIN YCII					
ECOLI|EnsemblGenome=b3540|UniProtKB=P37313	P37313	dppF	PTHR43776:SF6	TRANSPORT ATP-BINDING PROTEIN	DIPEPTIDE TRANSPORT ATP-BINDING PROTEIN DPPF	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b2427|UniProtKB=P77245	P77245	murR	PTHR30514:SF17	GLUCOKINASE	HTH-TYPE TRANSCRIPTIONAL REGULATOR MURR	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007	protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993	kinase#PC00137	
ECOLI|EnsemblGenome=b0451|UniProtKB=P69681	P69681	amtB	PTHR43029:SF10	AMMONIUM TRANSPORTER MEP2	AMMONIUM TRANSPORTER MEP2	passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267	nitrogen compound transport#GO:0071705;cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b0973|UniProtKB=P0ACD8	P0ACD8	hyaB	PTHR42958:SF3	HYDROGENASE-2 LARGE CHAIN	HYDROGENASE-1 LARGE CHAIN		metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;anaerobic electron transport chain#GO:0019645;anaerobic respiration#GO:0009061		oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0856|UniProtKB=P31135	P31135	potH	PTHR42929:SF3	INNER MEMBRANE ABC TRANSPORTER PERMEASE PROTEIN YDCU-RELATED-RELATED	PUTRESCINE TRANSPORT SYSTEM PERMEASE PROTEIN POTH	ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;polyamine transmembrane transporter activity#GO:0015203	establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987;nitrogen compound transport#GO:0071705	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0657|UniProtKB=P23930	P23930	lnt	PTHR38686:SF1	APOLIPOPROTEIN N-ACYLTRANSFERASE	APOLIPOPROTEIN N-ACYLTRANSFERASE		protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;lipoprotein metabolic process#GO:0042157;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	protein modifying enzyme#PC00260	
ECOLI|EnsemblGenome=b4169|UniProtKB=P26365	P26365	amiB	PTHR30404:SF6	N-ACETYLMURAMOYL-L-ALANINE AMIDASE	N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMIB	hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745	cellular process#GO:0009987;cell cycle process#GO:0022402;cell division#GO:0051301;cell cycle#GO:0007049;reproductive process#GO:0022414;reproductive process in single-celled organism#GO:0022413;FtsZ-dependent cytokinesis#GO:0043093;cytokinesis#GO:0000910	periplasmic space#GO:0042597;extracellular region#GO:0005576;cell envelope#GO:0030313;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165	hydrolase#PC00121	
ECOLI|EnsemblGenome=b3371|UniProtKB=P0AC00	P0AC00	frlB	PTHR10937:SF14	GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING	FRUCTOSELYSINE 6-PHOSPHATE DEGLYCASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;transaminase activity#GO:0008483	primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;UDP-N-acetylglucosamine biosynthetic process#GO:0006048;organophosphate biosynthetic process#GO:0090407;UDP-N-acetylglucosamine metabolic process#GO:0006047;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-sugar metabolic process#GO:0009225;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137		transaminase#PC00216	
ECOLI|EnsemblGenome=b2394|UniProtKB=P0CF93	P0CF93	insL3	PTHR33258:SF1	TRANSPOSASE INSL FOR INSERTION SEQUENCE ELEMENT IS186A-RELATED	TRANSPOSASE INSL FOR INSERTION SEQUENCE ELEMENT IS186A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b1188|UniProtKB=P29013	P29013	ycgB	PTHR30029:SF2	STAGE V SPORULATION PROTEIN R	STAGE V SPORULATION PROTEIN R					
ECOLI|EnsemblGenome=b3148|UniProtKB=P45465	P45465	yraN	PTHR34039:SF1	UPF0102 PROTEIN YRAN	UPF0102 PROTEIN YRAN					
ECOLI|EnsemblGenome=b4140|UniProtKB=P37147	P37147	fxsA	PTHR35335:SF1	UPF0716 PROTEIN FXSA	UPF0716 PROTEIN FXSA			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b2507|UniProtKB=P04079	P04079	guaA	PTHR11922:SF2	GMP SYNTHASE-RELATED	GMP SYNTHASE [GLUTAMINE-HYDROLYZING]	catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879	organophosphate biosynthetic process#GO:0090407;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	ligase#PC00142	De novo purine biosynthesis#P02738>GMP synthase#P02899
ECOLI|EnsemblGenome=b4141|UniProtKB=P39277	P39277	yjeH	PTHR42770:SF13	AMINO ACID TRANSPORTER-RELATED	L-METHIONINE_BRANCHED-CHAIN AMINO ACID EXPORTER YJEH	amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227;secondary carrier transporter#PC00258;amino acid transporter#PC00046	
ECOLI|EnsemblGenome=b3358|UniProtKB=P45537	P45537	yhfK	PTHR30509:SF23	P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT-RELATED	MEMBRANE PROTEIN			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b2148|UniProtKB=P23200	P23200	mglC	PTHR32196:SF18	ABC TRANSPORTER PERMEASE PROTEIN YPHD-RELATED-RELATED	GALACTOSE_METHYL GALACTOSIDE IMPORT PERMEASE PROTEIN MGLC			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b4242|UniProtKB=P0ABB8	P0ABB8	mgtA	PTHR24093:SF525	CATION TRANSPORTING ATPASE	MAGNESIUM-TRANSPORTING ATPASE, P-TYPE 1	monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229	primary active transporter#PC00068	
ECOLI|EnsemblGenome=b3771|UniProtKB=P05791	P05791	ilvD	PTHR43661:SF3	D-XYLONATE DEHYDRATASE	D-XYLONATE DEHYDRATASE YAGF-RELATED	catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	dehydratase#PC00091	Valine biosynthesis#P02785>Dihydroxy isovalerate dehydratase#P03218;Isoleucine biosynthesis#P02748>Dihydroxyacid dehydratase#P02998
ECOLI|EnsemblGenome=b3927|UniProtKB=P0AER0	P0AER0	glpF	PTHR43829:SF34	AQUAPORIN OR AQUAGLYCEROPORIN RELATED	GLYCEROL UPTAKE FACILITATOR PROTEIN	carbohydrate transmembrane transporter activity#GO:0015144;channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803	organic hydroxy compound transport#GO:0015850;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;carbohydrate transport#GO:0008643;transport#GO:0006810;carbohydrate transmembrane transport#GO:0034219;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|Gene_OrderedLocusName=JW5507|UniProtKB=P76655	P76655	yqiG	PTHR30451:SF4	OUTER MEMBRANE USHER PROTEIN	OUTER MEMBRANE USHER PROTEIN YQIG-RELATED	wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	cell adhesion#GO:0007155;cellular process#GO:0009987	external encapsulating structure#GO:0030312;cell outer membrane#GO:0009279;membrane#GO:0016020;extracellular region#GO:0005576;outer membrane#GO:0019867;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313		
ECOLI|EnsemblGenome=b3416|UniProtKB=P15977	P15977	malQ	PTHR32438:SF6	4-ALPHA-GLUCANOTRANSFERASE DPE1, CHLOROPLASTIC/AMYLOPLASTIC	4-ALPHA-GLUCANOTRANSFERASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757	metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;oligosaccharide metabolic process#GO:0009311;macromolecule metabolic process#GO:0043170;carbohydrate catabolic process#GO:0016052;polysaccharide catabolic process#GO:0000272;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;oligosaccharide catabolic process#GO:0009313;catabolic process#GO:0009056;polysaccharide metabolic process#GO:0005976	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	transferase#PC00220	
ECOLI|EnsemblGenome=b4506|UniProtKB=Q2EEQ2	Q2EEQ2	rpmJ2	PTHR47781:SF1	50S RIBOSOMAL PROTEIN L36 2	LARGE RIBOSOMAL SUBUNIT PROTEIN BL36B				translational protein#PC00263;ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b2743|UniProtKB=P0A7A5	P0A7A5	pcm	PTHR11579:SF0	PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE	PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE	S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;O-methyltransferase activity#GO:0008171;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276		cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	methyltransferase#PC00155;transferase#PC00220	
ECOLI|EnsemblGenome=b4241|UniProtKB=P36673	P36673	treR	PTHR30146:SF146	LACI-RELATED TRANSCRIPTIONAL REPRESSOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR TRER	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789		Lambda repressor-like transcription factor#PC00245;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b3666|UniProtKB=P0AGC0	P0AGC0	uhpT	PTHR43826:SF2	GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4	HEXOSE-6-PHOSPHATE:PHOSPHATE ANTIPORTER	organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;phosphate transmembrane transporter activity#GO:0005315;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291	transport#GO:0006810;inorganic anion transport#GO:0015698;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;phosphate ion transport#GO:0006817;organophosphate ester transport#GO:0015748	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	primary active transporter#PC00068	
ECOLI|EnsemblGenome=b4073|UniProtKB=P32709	P32709	nrfD	PTHR34856:SF2	PROTEIN NRFD	PROTEIN NRFD			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0967|UniProtKB=P75876	P75876	rlmI	PTHR42873:SF2	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE I	transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a rRNA#GO:0140102	RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;rRNA methylation#GO:0031167;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;rRNA base methylation#GO:0070475;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	RNA methyltransferase#PC00033;RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b3725|UniProtKB=P0AAH0	P0AAH0	pstB	PTHR43423:SF3	ABC TRANSPORTER I FAMILY MEMBER 17	PHOSPHATE IMPORT ATP-BINDING PROTEIN PSTB	active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;phosphate transmembrane transporter activity#GO:0005315	inorganic anion transport#GO:0015698;phosphate ion transport#GO:0006817;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b3391|UniProtKB=P34749	P34749	hofQ	PTHR30604:SF1	PROTEIN TRANSPORT PROTEIN HOFQ	DNA UTILIZATION PROTEIN HOFQ					
ECOLI|EnsemblGenome=b1400|UniProtKB=P77181	P77181	paaY	PTHR13061:SF65	DYNACTIN SUBUNIT P25	CARNITINE OPERON PROTEIN CAIE-RELATED	hydrolase activity#GO:0016787;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;acyl-CoA hydrolase activity#GO:0016289;deacylase activity#GO:0160215	metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;carnitine metabolic process#GO:0009437;cellular process#GO:0009987		microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156	
ECOLI|Gene_OrderedLocusName=b4661|UniProtKB=P77196	P77196	yfcU	PTHR30451:SF10	OUTER MEMBRANE USHER PROTEIN	OUTER MEMBRANE USHER PROTEIN YFCU-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829	cellular process#GO:0009987;cell adhesion#GO:0007155	membrane#GO:0016020;cell outer membrane#GO:0009279;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;outer membrane#GO:0019867;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313		
ECOLI|EnsemblGenome=b1832|UniProtKB=P76270	P76270	msrC	PTHR21021:SF15	GAF/PUTATIVE CYTOSKELETAL PROTEIN	FREE METHIONINE-R-SULFOXIDE REDUCTASE	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b1543|UniProtKB=P77228	P77228	ydfJ	PTHR43045:SF4	SHIKIMATE TRANSPORTER	TRANSPORTER YDFJ-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b3649|UniProtKB=P0A800	P0A800	rpoZ	PTHR34476:SF1	DNA-DIRECTED RNA POLYMERASE SUBUNIT OMEGA	DNA-DIRECTED RNA POLYMERASE SUBUNIT OMEGA	RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;binding#GO:0005488	macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070	RNA polymerase complex#GO:0030880;cytosol#GO:0005829;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;DNA-directed RNA polymerase complex#GO:0000428	RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019	
ECOLI|EnsemblGenome=b2106|UniProtKB=P76425	P76425	rcnA	PTHR40659:SF1	NICKEL/COBALT EFFLUX SYSTEM RCNA	NICKEL_COBALT EFFLUX SYSTEM RCNA	transition metal ion transmembrane transporter activity#GO:0046915;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873	response to metal ion#GO:0010038;response to stimulus#GO:0050896;response to chemical#GO:0042221	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b2508|UniProtKB=P0ADG7	P0ADG7	guaB	PTHR11911:SF111	INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED	INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE	catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614	nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate biosynthetic process#GO:0090407;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281		dehydrogenase#PC00092	De novo purine biosynthesis#P02738>IMP dehydrogenase#P02895
ECOLI|EnsemblGenome=b0087|UniProtKB=P0A6W3	P0A6W3	mraY	PTHR22926:SF6	PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE	PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE	phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740	cellular component organization#GO:0016043;cell wall macromolecule biosynthetic process#GO:0044038;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cell wall organization or biogenesis#GO:0071554;cell wall organization#GO:0071555;biosynthetic process#GO:0009058;metabolic process#GO:0008152;cell wall biogenesis#GO:0042546;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cell wall macromolecule metabolic process#GO:0044036;external encapsulating structure organization#GO:0045229	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	glycosyltransferase#PC00111;transferase#PC00220	
ECOLI|EnsemblGenome=b0769|UniProtKB=P0AAV8	P0AAV8	ybhH	PTHR43709:SF3	ACONITATE ISOMERASE-RELATED	ISOMERASE YBHH-RELATED	catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860			isomerase#PC00135	
ECOLI|EnsemblGenome=b3873|UniProtKB=P32134	P32134	yihM	PTHR12110:SF53	HYDROXYPYRUVATE ISOMERASE	BLR3667 PROTEIN				isomerase#PC00135	
ECOLI|EnsemblGenome=b3224|UniProtKB=P41036	P41036	nanT	PTHR23508:SF3	CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG	SIALIC ACID TRANSPORTER NANT	solute:proton symporter activity#GO:0015295;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate derivative transmembrane transporter activity#GO:1901505;proton transmembrane transporter activity#GO:0015078;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804	establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b3387|UniProtKB=P0AEE8	P0AEE8	dam	PTHR30481:SF3	DNA ADENINE METHYLASE	DNA ADENINE METHYLASE	DNA binding#GO:0003677;cation binding#GO:0043169;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;nucleic acid binding#GO:0003676;catalytic activity, acting on DNA#GO:0140097;sequence-specific DNA binding#GO:0043565;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824	cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;mismatch repair#GO:0006298;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896		DNA methyltransferase#PC00013;DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b2280|UniProtKB=P0AFE0	P0AFE0	nuoJ	PTHR33269:SF17	NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 6	NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 6				oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0874|UniProtKB=P75826	P75826	lysO	PTHR35804:SF1	LYSINE EXPORTER LYSO	LYSINE EXPORTER LYSO	carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179;basic amino acid transmembrane transporter activity#GO:0015174;efflux transmembrane transporter activity#GO:0015562		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b4323|UniProtKB=P39160	P39160	uxuB	PTHR43362:SF7	MANNITOL DEHYDROGENASE DSF1-RELATED	D-MANNONATE OXIDOREDUCTASE	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616	carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid catabolic process#GO:0072329;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436		oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0150|UniProtKB=P06971	P06971	fhuA	PTHR32552:SF92	FERRICHROME IRON RECEPTOR-RELATED	FERRICHROME OUTER MEMBRANE TRANSPORTER_PHAGE RECEPTOR	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;siderophore-iron transmembrane transporter activity#GO:0015343	establishment of localization#GO:0051234;import into cell#GO:0098657;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;iron coordination entity transport#GO:1901678;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;siderophore-iron import into cell#GO:0033214;monoatomic ion homeostasis#GO:0050801;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;siderophore-dependent iron import pathway#GO:0180060;cellular localization#GO:0051641;monoatomic ion transport#GO:0006811;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;metal ion transport#GO:0030001;iron import into cell#GO:0033212;intracellular monoatomic ion homeostasis#GO:0006873	cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;outer membrane#GO:0019867;membrane#GO:0016020;cell outer membrane#GO:0009279;external encapsulating structure#GO:0030312		
ECOLI|EnsemblGenome=b3848|UniProtKB=P27862	P27862	yigZ	PTHR16301:SF20	IMPACT-RELATED	IMPACT FAMILY MEMBER YIGZ		regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of translational initiation#GO:0006446;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		
ECOLI|EnsemblGenome=b3847|UniProtKB=P21165	P21165	pepQ	PTHR43226:SF8	XAA-PRO AMINOPEPTIDASE 3	XAA-PRO DIPEPTIDASE	catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233	macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	metalloprotease#PC00153	
ECOLI|EnsemblGenome=b2471|UniProtKB=P24178	P24178	yffB	PTHR30041:SF8	ARSENATE REDUCTASE	PROTEIN YFFB				reductase#PC00198	
ECOLI|Gene_OrderedLocusName=JW3236|UniProtKB=P45766	P45766	yhdW	PTHR30085:SF7	AMINO ACID ABC TRANSPORTER PERMEASE	AMINO-ACID ABC TRANSPORTER-BINDING PROTEIN YHDW-RELATED		amino acid transport#GO:0006865;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234		primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b1924|UniProtKB=P24216	P24216	fliD	PTHR30288:SF0	FLAGELLAR CAP/ASSEMBLY PROTEIN FLID	FLAGELLAR HOOK-ASSOCIATED PROTEIN 2		archaeal or bacterial-type flagellum-dependent cell motility#GO:0097588;cilium or flagellum-dependent cell motility#GO:0001539;cellular process#GO:0009987;bacterial-type flagellum-dependent cell motility#GO:0071973;cell motility#GO:0048870	organelle#GO:0043226;bacterial-type flagellum#GO:0009288;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;cell projection#GO:0042995	chaperone#PC00072	
ECOLI|EnsemblGenome=b2256|UniProtKB=P76472	P76472	arnD	PTHR10587:SF137	GLYCOSYL TRANSFERASE-RELATED	4-DEOXY-4-FORMAMIDO-L-ARABINOSE-PHOSPHOUNDECAPRENOL DEFORMYLASE ARND-RELATED	catalytic activity#GO:0003824;deacylase activity#GO:0160215;deacetylase activity#GO:0019213			transferase#PC00220;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3503|UniProtKB=P0AB96	P0AB96	arsC	PTHR30041:SF5	ARSENATE REDUCTASE	ARSENATE REDUCTASE-RELATED		response to stimulus#GO:0050896;response to chemical#GO:0042221		reductase#PC00198	
ECOLI|EnsemblGenome=b1617|UniProtKB=P05804	P05804	uidA	PTHR10066:SF67	BETA-GLUCURONIDASE	BETA-GLUCURONIDASE					
ECOLI|EnsemblGenome=b1184|UniProtKB=P04152	P04152	umuC	PTHR11076:SF34	DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER	PROTEIN UMUC	DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;DNA-directed DNA polymerase activity#GO:0003887	translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;DNA synthesis involved in DNA replication#GO:0090592;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187		DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b0444|UniProtKB=P77756	P77756	queC	PTHR42914:SF1	7-CYANO-7-DEAZAGUANINE SYNTHASE	7-CYANO-7-DEAZAGUANINE SYNTHASE		macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble base modification#GO:0002097;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412		ligase#PC00142	
ECOLI|EnsemblGenome=b2986|UniProtKB=Q46844	Q46844	yghT	PTHR10344:SF4	THYMIDYLATE KINASE	THYMIDYLATE KINASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, phosphate group as acceptor#GO:0016776	nucleoside diphosphate metabolic process#GO:0009132;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	transferase#PC00220;nucleotide kinase#PC00172;kinase#PC00137	De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTMP kinase#P02916
ECOLI|EnsemblGenome=b2276|UniProtKB=P0AFF0	P0AFF0	nuoN	PTHR22773:SF41	NADH DEHYDROGENASE	NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 2	oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;primary active transmembrane transporter activity#GO:0015399;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324;oxidoreductase activity, acting on NAD(P)H#GO:0016651;NADH dehydrogenase activity#GO:0003954	cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;metabolic process#GO:0008152;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980	catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b0008|UniProtKB=P0A870	P0A870	talB	PTHR10683:SF42	TRANSALDOLASE	TRANSALDOLASE B	transketolase or transaldolase activity#GO:0016744;transaldolase activity#GO:0004801;transferase activity#GO:0016740;catalytic activity#GO:0003824	pentose-phosphate shunt#GO:0006098;NADPH regeneration#GO:0006740;glyceraldehyde-3-phosphate metabolic process#GO:0019682;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;pentose-phosphate shunt, non-oxidative branch#GO:0009052;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing small molecule metabolic process#GO:0055086;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;nucleobase-containing compound metabolic process#GO:0006139	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	lyase#PC00144;aldolase#PC00044;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2576|UniProtKB=P21507	P21507	srmB	PTHR47959:SF3	ATP-DEPENDENT RNA HELICASE RHLE-RELATED	ATP-DEPENDENT RNA HELICASE SRMB	macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	RNA helicase#PC00032	
ECOLI|EnsemblGenome=b1744|UniProtKB=P76215	P76215	astE	PTHR15162:SF10	ASPARTOACYLASE	SUCCINYLGLUTAMATE DESUCCINYLASE	hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811				
ECOLI|EnsemblGenome=b1061|UniProtKB=P0ABR1	P0ABR1	dinI	PTHR36572:SF2	DNA DAMAGE-INDUCIBLE PROTEIN I-RELATED	DNA DAMAGE-INDUCIBLE PROTEIN I		response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;SOS response#GO:0009432;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896			
ECOLI|EnsemblGenome=b1701|UniProtKB=P38135	P38135	fadK	PTHR43859:SF68	ACYL-ACTIVATING ENZYME	MEDIUM-CHAIN FATTY-ACID--COA LIGASE	ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874	biosynthetic process#GO:0009058;antibiotic biosynthetic process#GO:0017000;cellular process#GO:0009987;phenol-containing compound metabolic process#GO:0018958;phenol-containing compound biosynthetic process#GO:0046189;siderophore biosynthetic process#GO:0019290;secondary metabolic process#GO:0019748;peptide metabolic process#GO:0006518;siderophore metabolic process#GO:0009237;secondary metabolite biosynthetic process#GO:0044550;metabolic process#GO:0008152		ligase#PC00142	
ECOLI|EnsemblGenome=b2891|UniProtKB=P07012	P07012	prfB	PTHR43116:SF5	PEPTIDE CHAIN RELEASE FACTOR 2	PEPTIDE CHAIN RELEASE FACTOR RF2	translation factor activity#GO:0180051	biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;protein-containing complex disassembly#GO:0032984;protein biosynthetic process#GO:0160307;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;translation#GO:0006412;translational termination#GO:0006415	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	translational protein#PC00263;translation factor#PC00223;translation release factor#PC00225	
ECOLI|EnsemblGenome=b1876|UniProtKB=P11875	P11875	argS	PTHR11956:SF12	ARGINYL-TRNA SYNTHETASE	ARGININE--TRNA LIGASE	catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640	biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	aminoacyl-tRNA synthetase#PC00047	
ECOLI|EnsemblGenome=b4353|UniProtKB=P0ADC8	P0ADC8	yjiX	PTHR38453:SF1	CYTOPLASMIC PROTEIN-RELATED	SELENOPROTEIN					
ECOLI|EnsemblGenome=b1708|UniProtKB=P23898	P23898	nlpC	PTHR47360:SF1	MUREIN DD-ENDOPEPTIDASE MEPS/MUREIN LD-CARBOXYPEPTIDASE	ENDOPEPTIDASE NLPC-RELATED	hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824	glycosaminoglycan metabolic process#GO:0030203;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;peptidoglycan turnover#GO:0009254;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;peptidoglycan metabolic process#GO:0000270;macromolecule metabolic process#GO:0043170			
ECOLI|EnsemblGenome=b3057|UniProtKB=P60932	P60932	uppP	PTHR30622:SF3	UNDECAPRENYL-DIPHOSPHATASE	UNDECAPRENYL-DIPHOSPHATASE	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787	glycosaminoglycan metabolic process#GO:0030203;peptidoglycan metabolic process#GO:0000270;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;macromolecule metabolic process#GO:0043170	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	phosphatase#PC00181	
ECOLI|EnsemblGenome=b3098|UniProtKB=P64581	P64581	yqjD	PTHR35893:SF5	INNER MEMBRANE PROTEIN-RELATED	INNER MEMBRANE PROTEIN	binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b3289|UniProtKB=P36929	P36929	rsmB	PTHR22807:SF78	NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN  DOMAIN-CONTAINING	RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE B	catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824	rRNA processing#GO:0006364;methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA methylation#GO:0031167;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;rRNA base methylation#GO:0070475;cellular process#GO:0009987;cellular component biogenesis#GO:0044085	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	RNA methyltransferase#PC00033;RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b2293|UniProtKB=P77625	P77625	hxpA	PTHR43481:SF11	FRUCTOSE-1-PHOSPHATE PHOSPHATASE	HEXITOL PHOSPHATASE A	hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788	carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987		hydrolase#PC00121;carbohydrate phosphatase#PC00066	
ECOLI|EnsemblGenome=b2159|UniProtKB=P0A6C1	P0A6C1	nfo	PTHR21445:SF0	ENDONUCLEASE IV  ENDODEOXYRIBONUCLEASE IV	ENDONUCLEASE 4	phosphoric diester hydrolase activity#GO:0008081;catalytic activity, acting on DNA#GO:0140097;phosphoric ester hydrolase activity#GO:0042578;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518	cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896		endodeoxyribonuclease#PC00093	
ECOLI|EnsemblGenome=b3710|UniProtKB=P31462	P31462	mdtL	PTHR23502:SF57	MAJOR FACILITATOR SUPERFAMILY	MULTIDRUG RESISTANCE PROTEIN MDTL	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	transport#GO:0006810;xenobiotic transport#GO:0042908;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;xenobiotic detoxification by transmembrane export across the plasma membrane#GO:1990961;cellular process#GO:0009987;export from cell#GO:0140352;detoxification#GO:0098754;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to toxic substance#GO:0009636	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b1580|UniProtKB=P38105	P38105	rspB	PTHR43161:SF11	SORBITOL DEHYDROGENASE	STARVATION-SENSING PROTEIN RSPB				oxidoreductase#PC00176;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b3035|UniProtKB=P02930	P02930	tolC	PTHR30026:SF24	OUTER MEMBRANE PROTEIN TOLC	OUTER MEMBRANE PROTEIN TOLC	wide pore channel activity#GO:0022829;efflux transmembrane transporter activity#GO:0015562;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		membrane#GO:0016020;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495	transporter#PC00227	
ECOLI|EnsemblGenome=b2021|UniProtKB=P06986	P06986	hisC	PTHR42885:SF2	HISTIDINOL-PHOSPHATE AMINOTRANSFERASE-RELATED	HISTIDINOL-PHOSPHATE AMINOTRANSFERASE				transferase#PC00220;transaminase#PC00216	Histidine biosynthesis#P02747>Histidinephosphate aminotransferase#P02991
ECOLI|EnsemblGenome=b3552|UniProtKB=P37665	P37665	yiaD	PTHR30329:SF24	STATOR ELEMENT OF FLAGELLAR MOTOR COMPLEX	LIPOPROTEIN YIAD-RELATED				structural protein#PC00211	
ECOLI|EnsemblGenome=b0828|UniProtKB=P37595	P37595	iaaA	PTHR10188:SF44	L-ASPARAGINASE	ISOASPARTYL PEPTIDASE_L-ASPARAGINASE-RELATED				protein modifying enzyme#PC00260;protease#PC00190	
ECOLI|EnsemblGenome=b3002|UniProtKB=P67244	P67244	yqhA	PTHR38596:SF1	UPF0114 PROTEIN YQHA	UPF0114 PROTEIN YQHA			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b3632|UniProtKB=P25742	P25742	waaQ	PTHR30160:SF1	TETRAACYLDISACCHARIDE 4'-KINASE-RELATED	LIPOPOLYSACCHARIDE HEPTOSYLTRANSFERASE 3-RELATED	glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824	carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;oligosaccharide metabolic process#GO:0009311;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;oligosaccharide biosynthetic process#GO:0009312;lipopolysaccharide metabolic process#GO:0008653;polysaccharide biosynthetic process#GO:0000271;polysaccharide metabolic process#GO:0005976;liposaccharide metabolic process#GO:1903509;lipopolysaccharide core region biosynthetic process#GO:0009244;lipopolysaccharide biosynthetic process#GO:0009103;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	carbohydrate kinase#PC00065;kinase#PC00137	
ECOLI|EnsemblGenome=b2534|UniProtKB=P77538	P77538	yfhR	PTHR12277:SF205	ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN	SAM DOMAIN-CONTAINING PROTEIN				serine protease#PC00203	
ECOLI|EnsemblGenome=b0694|UniProtKB=P21866	P21866	kdpE	PTHR48111:SF50	REGULATOR OF RPOS	KDP OPERON TRANSCRIPTIONAL REGULATORY PROTEIN KDPE	DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;molecular transducer activity#GO:0060089;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993	helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b1606|UniProtKB=P0AFS3	P0AFS3	folM	PTHR43639:SF11	OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G02870)	DIHYDROMONAPTERIN REDUCTASE	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3947|UniProtKB=P32670	P32670	ptsA	PTHR46244:SF4	PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE	MULTIPHOSPHORYL TRANSFER PROTEIN 1-RELATED	transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;transferase activity, transferring phosphorus-containing groups#GO:0016772	carbohydrate derivative transport#GO:1901264;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179		protein modifying enzyme#PC00260	
ECOLI|EnsemblGenome=b2411|UniProtKB=P15042	P15042	ligA	PTHR23389:SF9	CHROMOSOME TRANSMISSION FIDELITY FACTOR 18	DNA LIGASE	catalytic activity, acting on DNA#GO:0140097;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b3508|UniProtKB=P0AFV2	P0AFV2	yhiD	PTHR33778:SF5	PROTEIN MGTC	MAGNESIUM TRANSPORTER YHID-RELATED			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b1360|UniProtKB=P77546	P77546	ydaV	PTHR30050:SF4	CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA	ATP-BINDING PROTEIN RV3427C IN INSERTION SEQUENCE-RELATED	binding#GO:0005488;nucleic acid binding#GO:0003676;DNA replication origin binding#GO:0003688;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690	DNA replication#GO:0006260;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;DNA replication initiation#GO:0006270;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261		DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b4159|UniProtKB=P39285	P39285	mscM	PTHR30347:SF9	POTASSIUM CHANNEL RELATED	MINICONDUCTANCE MECHANOSENSITIVE CHANNEL MSCM	channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;gated channel activity#GO:0022836;passive transmembrane transporter activity#GO:0022803		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	ion channel#PC00133	
ECOLI|EnsemblGenome=b1175|UniProtKB=P0AEZ3	P0AEZ3	minD	PTHR43384:SF6	SEPTUM SITE-DETERMINING PROTEIN MIND HOMOLOG, CHLOROPLASTIC-RELATED	SEPTUM SITE-DETERMINING PROTEIN MIND HOMOLOG, CHLOROPLASTIC	ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP binding#GO:0005524;ATP-dependent activity#GO:0140657;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555		cytosol#GO:0005829;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cytoplasmic side of membrane#GO:0098562;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b1857|UniProtKB=P39172	P39172	znuA	PTHR42953:SF3	HIGH-AFFINITY ZINC UPTAKE SYSTEM PROTEIN ZNUA-RELATED	HIGH-AFFINITY ZINC UPTAKE SYSTEM PROTEIN ZNUA		zinc ion transport#GO:0006829;metal ion transport#GO:0030001;transport#GO:0006810;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812			
ECOLI|EnsemblGenome=b0361|UniProtKB=P0CF53	P0CF53	insD1	PTHR37936:SF3	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b2163|UniProtKB=P0A9E9	P0A9E9	yeiL	PTHR24567:SF26	CRP FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN	REGULATORY PROTEIN YEIL	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110		cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b1528|UniProtKB=P31122	P31122	sotB	PTHR43124:SF4	PURINE EFFLUX PUMP PBUE	SUGAR EFFLUX TRANSPORTER	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b2913|UniProtKB=P0A9T0	P0A9T0	serA	PTHR10996:SF282	2-HYDROXYACID DEHYDROGENASE-RELATED	D-3-PHOSPHOGLYCERATE DEHYDROGENASE 1-RELATED				dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	Serine glycine biosynthesis#P02776>Phosphoglycerate dehydrogenase#P03160
ECOLI|EnsemblGenome=b0604|UniProtKB=P77202	P77202	dsbG	PTHR35272:SF4	THIOL:DISULFIDE INTERCHANGE PROTEIN DSBC-RELATED	THIOL:DISULFIDE INTERCHANGE PROTEIN DSBG	catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756;intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853	metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058	cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313;extracellular region#GO:0005576;periplasmic space#GO:0042597		
ECOLI|EnsemblGenome=b0727|UniProtKB=P0AFG6	P0AFG6	sucB	PTHR43416:SF46	DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED	DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX	catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096	cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333		transferase#PC00220	
ECOLI|EnsemblGenome=b2865|UniProtKB=Q46798	Q46798	ygeR	PTHR21666:SF269	PEPTIDASE-RELATED	METALLOENDOPEPTIDASE	metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824		cell division site#GO:0032153;cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;cell outer membrane#GO:0009279;membrane#GO:0016020;outer membrane#GO:0019867;extracellular region#GO:0005576	protease#PC00190;metalloprotease#PC00153	
ECOLI|EnsemblGenome=b0982|UniProtKB=P0ACZ2	P0ACZ2	etp	PTHR11717:SF31	LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE	LOW MOLECULAR WEIGHT PROTEIN-TYROSINE-PHOSPHATASE ETP-RELATED	phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824			protein phosphatase#PC00195	
ECOLI|EnsemblGenome=b0285|UniProtKB=P77324	P77324	paoB	PTHR42659:SF5	XANTHINE DEHYDROGENASE SUBUNIT C-RELATED	ALDEHYDE OXIDOREDUCTASE FAD-BINDING SUBUNIT PAOB	catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491		protein-containing complex#GO:0032991;oxidoreductase complex#GO:1990204;catalytic complex#GO:1902494	dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b4167|UniProtKB=P31806	P31806	nnr	PTHR12592:SF4	ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE FAMILY MEMBER	BIFUNCTIONAL NAD(P)H-HYDRATE REPAIR ENZYME NNR	hydro-lyase activity#GO:0016836;isomerase activity#GO:0016853;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854	cellular process#GO:0009987;metabolic process#GO:0008152		metabolite interconversion enzyme#PC00262;dehydratase#PC00091	
ECOLI|EnsemblGenome=b2997|UniProtKB=P69741	P69741	hybO	PTHR30013:SF7	NIFE / NIFESE HYDROGENASE SMALL SUBUNIT FAMILY MEMBER	HYDROGENASE-2 SMALL CHAIN		anaerobic respiration#GO:0009061;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane#GO:0016020;catalytic complex#GO:1902494	metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b4209|UniProtKB=P69506	P69506	ytfE	PTHR36438:SF2	IRON-SULFUR CLUSTER REPAIR PROTEIN YTFE	IRON-SULFUR CLUSTER REPAIR PROTEIN YTFE	oxidoreductase activity#GO:0016491;iron ion binding#GO:0005506;catalytic activity#GO:0003824;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167	macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;protein repair#GO:0030091;metabolic process#GO:0008152;primary metabolic process#GO:0044238	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b4400|UniProtKB=P08369	P08369	creD	PTHR30092:SF0	INNER MEMBRANE PROTEIN CRED	INNER MEMBRANE PROTEIN CRED			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b3249|UniProtKB=P0ABH4	P0ABH4	mreD	PTHR37484:SF1	ROD SHAPE-DETERMINING PROTEIN MRED	ROD SHAPE-DETERMINING PROTEIN MRED		regulation of anatomical structure morphogenesis#GO:0022603;regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of cell shape#GO:0008360;regulation of biological process#GO:0050789	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b4034|UniProtKB=P0AEX9	P0AEX9	malE	PTHR30061:SF50	MALTOSE-BINDING PERIPLASMIC PROTEIN	MALTOSE_MALTODEXTRIN-BINDING PERIPLASMIC PROTEIN	carbohydrate binding#GO:0030246;binding#GO:0005488;oligosaccharide binding#GO:0070492	establishment of localization#GO:0051234;localization#GO:0051179;macromolecule localization#GO:0033036;transport#GO:0006810;carbohydrate transport#GO:0008643	transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;ATPase dependent transmembrane transport complex#GO:0098533;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;ATP-binding cassette (ABC) transporter complex#GO:0043190;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886	transporter#PC00227;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b0353|UniProtKB=P77589	P77589	mhpT	PTHR23511:SF46	SYNAPTIC VESICLE GLYCOPROTEIN 2	3-(3-HYDROXY-PHENYL)PROPIONATE TRANSPORTER	solute:proton symporter activity#GO:0015295;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804	establishment of localization#GO:0051234;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810	membrane#GO:0016020;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2701|UniProtKB=P41052	P41052	mltB	PTHR30163:SF9	MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE B	MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE B	peptidoglycan lytic transglycosylase activity#GO:0008933;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824;carbon-oxygen lyase activity, acting on polysaccharides#GO:0016837;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829	macromolecule catabolic process#GO:0009057;peptidoglycan metabolic process#GO:0000270;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;glycosaminoglycan catabolic process#GO:0006027;aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170;glycosaminoglycan metabolic process#GO:0030203;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136		lyase#PC00144;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0834|UniProtKB=P75801	P75801	dgcI	PTHR45138:SF31	REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM	DIGUANYLATE CYCLASE DGCM-RELATED	nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772	regulation of cellular process#GO:0050794;regulation of locomotion#GO:0040012;negative regulation of cell motility#GO:2000146;negative regulation of locomotion#GO:0040013;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cell motility#GO:2000145;cell-substrate adhesion#GO:0031589;negative regulation of cellular process#GO:0048523;single-species biofilm formation#GO:0044010;cell adhesion#GO:0007155	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2912|UniProtKB=P0AC28	P0AC28	ygfA	PTHR23407:SF12	ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE	5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE	catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879	tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152;tetrahydrofolate metabolic process#GO:0046653;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;biosynthetic process#GO:0009058;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;small molecule metabolic process#GO:0044281	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	ligase#PC00142	
ECOLI|EnsemblGenome=b1923|UniProtKB=P04949	P04949	fliC	PTHR42792:SF2	FLAGELLIN	FLAGELLIN				structural protein#PC00211	
ECOLI|EnsemblGenome=b3892|UniProtKB=P0AEL0	P0AEL0	fdoI	PTHR30074:SF2	FORMATE DEHYDROGENASE, NITRATE-INDUCIBLE, CYTOCHROME B556 FDN  SUBUNIT	FORMATE DEHYDROGENASE, CYTOCHROME B556(FDO) SUBUNIT	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	small molecule metabolic process#GO:0044281;anaerobic respiration#GO:0009061;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;generation of precursor metabolites and energy#GO:0006091	cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cell periphery#GO:0071944;catalytic complex#GO:1902494	dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1460|UniProtKB=P28917	P28917	ydcC	PTHR30298:SF0	H REPEAT-ASSOCIATED PREDICTED TRANSPOSASE	PROTEIN YBFL-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b4284|UniProtKB=P0CF90	P0CF90	insI4	PTHR10948:SF23	TRANSPOSASE	TRANSPOSASE INSI FOR INSERTION SEQUENCE ELEMENT IS30A-RELATED	catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640	nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170		viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b3408|UniProtKB=P0AEL3	P0AEL3	feoA	PTHR42954:SF2	FE(2+) TRANSPORT PROTEIN A	FE(2+) TRANSPORT PROTEIN A		response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;cellular process#GO:0009987;cellular response to stimulus#GO:0051716			
ECOLI|EnsemblGenome=b3819|UniProtKB=P27844	P27844	rarD	PTHR22911:SF139	ACYL-MALONYL CONDENSING ENZYME-RELATED	PROTEIN RARD			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b0875|UniProtKB=P60844	P60844	aqpZ	PTHR19139:SF199	AQUAPORIN TRANSPORTER	AQUAPORIN			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b2794|UniProtKB=Q46920	Q46920	queF	PTHR34354:SF1	NADPH-DEPENDENT 7-CYANO-7-DEAZAGUANINE REDUCTASE	NADPH-DEPENDENT 7-CYANO-7-DEAZAGUANINE REDUCTASE	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble base modification#GO:0002097;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	reductase#PC00198	
ECOLI|EnsemblGenome=b3313|UniProtKB=P0ADY7	P0ADY7	rplP	PTHR12220:SF26	50S/60S RIBOSOMAL PROTEIN L16	LARGE RIBOSOMAL SUBUNIT PROTEIN UL16	structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488;rRNA binding#GO:0019843;structural molecule activity#GO:0005198;RNA binding#GO:0003723			ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b4356|UniProtKB=P39398	P39398	lgoT	PTHR11662:SF399	SOLUTE CARRIER FAMILY 17	MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN				secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b1293|UniProtKB=P0AGH3	P0AGH3	sapB	PTHR43163:SF4	DIPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN DPPB-RELATED	PUTRESCINE EXPORT SYSTEM PERMEASE PROTEIN SAPB	oligopeptide transmembrane transporter activity#GO:0035673;dipeptide transmembrane transporter activity#GO:0071916;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b4139|UniProtKB=P0AC38	P0AC38	aspA	PTHR42696:SF2	ASPARTATE AMMONIA-LYASE	ASPARTATE AMMONIA-LYASE				metabolite interconversion enzyme#PC00262;lyase#PC00144	
ECOLI|EnsemblGenome=b4196|UniProtKB=P39304	P39304	ulaD	PTHR35039:SF3	3-KETO-L-GULONATE-6-PHOSPHATE DECARBOXYLASE SGBH-RELATED	3-KETO-L-GULONATE-6-PHOSPHATE DECARBOXYLASE SGBH-RELATED	lyase activity#GO:0016829;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830	carbohydrate catabolic process#GO:0016052;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;L-ascorbic acid metabolic process#GO:0019852		metabolite interconversion enzyme#PC00262;decarboxylase#PC00089	
ECOLI|EnsemblGenome=b3539|UniProtKB=P37660	P37660	yhjV	PTHR35334:SF5	SERINE TRANSPORTER	INNER MEMBRANE TRANSPORT PROTEIN YHJV	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;amino acid transport#GO:0006865	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b1993|UniProtKB=P0AE76	P0AE76	cobU	PTHR34848:SF1	BIFUNCTIONAL ADENOSYLCOBALAMIN BIOSYNTHESIS PROTEIN COBU	BIFUNCTIONAL ADENOSYLCOBALAMIN BIOSYNTHESIS PROTEIN COBU					
ECOLI|EnsemblGenome=b1612|UniProtKB=P0AC33	P0AC33	fumA	PTHR30389:SF0	FUMARATE HYDRATASE-RELATED	FUMARATE HYDRATASE CLASS I, AEROBIC	catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829	primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;cellular process#GO:0009987;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	lyase#PC00144;hydratase#PC00120	
ECOLI|EnsemblGenome=b2918|UniProtKB=P27254	P27254	argK	PTHR23408:SF3	METHYLMALONYL-COA MUTASE	METHYLMALONIC ACIDURIA TYPE A PROTEIN, MITOCHONDRIAL	hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787		intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	mutase#PC00160	
ECOLI|EnsemblGenome=b3479|UniProtKB=P33593	P33593	nikD	PTHR24220:SF607	IMPORT ATP-BINDING PROTEIN	NICKEL IMPORT ATP-BINDING PROTEIN NIKD-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	oligopeptide transport#GO:0006857;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987;oligopeptide transmembrane transport#GO:0035672;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b3856|UniProtKB=P32125	P32125	mobB	PTHR40072:SF1	MOLYBDOPTERIN-GUANINE DINUCLEOTIDE BIOSYNTHESIS ADAPTER PROTEIN-RELATED	MOLYBDOPTERIN-GUANINE DINUCLEOTIDE BIOSYNTHESIS ADAPTER PROTEIN	ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561			scaffold/adaptor protein#PC00226	
ECOLI|EnsemblGenome=b1716|UniProtKB=P0A7L3	P0A7L3	rplT	PTHR10986:SF26	39S RIBOSOMAL PROTEIN L20	LARGE RIBOSOMAL SUBUNIT PROTEIN BL20	structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198		cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904	ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b0237|UniProtKB=P15288	P15288	pepD	PTHR43501:SF1	CYTOSOL NON-SPECIFIC DIPEPTIDASE	CYTOSOL NON-SPECIFIC DIPEPTIDASE	exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;metalloexopeptidase activity#GO:0008235	peptide metabolic process#GO:0006518;catabolic process#GO:0009056;cellular process#GO:0009987;peptide catabolic process#GO:0043171;metabolic process#GO:0008152	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	protease#PC00190;metalloprotease#PC00153	
ECOLI|EnsemblGenome=b1309|UniProtKB=P76041	P76041	ycjM	PTHR10357:SF214	ALPHA-GLUCOSIDASE FAMILY MEMBER	GLUCOSYLGLYCERATE PHOSPHORYLASE				metabolite interconversion enzyme#PC00262;amylase#PC00048	
ECOLI|EnsemblGenome=b1101|UniProtKB=P69786	P69786	ptsG	PTHR30009:SF25	CYTOCHROME C-TYPE SYNTHESIS PROTEIN AND PTS TRANSMEMBRANE COMPONENT	PTS SYSTEM GLUCOSE-SPECIFIC EIICB COMPONENT-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;active transmembrane transporter activity#GO:0022804;protein-phosphocysteine-sugar phosphotransferase activity#GO:0090563;carbohydrate transmembrane transporter activity#GO:0015144;phosphotransferase activity, alcohol group as acceptor#GO:0016773	transport#GO:0006810;carbohydrate transport#GO:0008643;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;import into cell#GO:0098657;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;D-glucose transmembrane transport#GO:1904659;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b0600|UniProtKB=P77806	P77806	ybdL	PTHR43807:SF25	FI04487P	METHIONINE AMINOTRANSFERASE	transaminase activity#GO:0008483;catalytic activity#GO:0003824;transferase activity#GO:0016740			metabolite interconversion enzyme#PC00262;transaminase#PC00216;transferase#PC00220	
ECOLI|EnsemblGenome=b1497|UniProtKB=P76134	P76134	ydeM	PTHR43273:SF3	ANAEROBIC SULFATASE-MATURATING ENZYME HOMOLOG ASLB-RELATED	ANAEROBIC SULFATASE-MATURATING ENZYME HOMOLOG ASLB-RELATED					
ECOLI|EnsemblGenome=b2803|UniProtKB=P11553	P11553	fucK	PTHR10196:SF60	SUGAR KINASE	L-FUCULOKINASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773	small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	kinase#PC00137;carbohydrate kinase#PC00065	
ECOLI|EnsemblGenome=b3590|UniProtKB=P14081	P14081	selB	PTHR42854:SF18	EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER	SELENOCYSTEINE-SPECIFIC ELONGATION FACTOR	binding#GO:0005488;nucleic acid binding#GO:0003676;tRNA binding#GO:0000049;RNA binding#GO:0003723			translation initiation factor#PC00224	
ECOLI|EnsemblGenome=b1372|UniProtKB=P76072	P76072	stfR	PTHR35191:SF1	PROPHAGE SIDE TAIL FIBER PROTEIN HOMOLOG STFQ-RELATED	PROPHAGE SIDE TAIL FIBER PROTEIN HOMOLOG STFQ-RELATED					
ECOLI|EnsemblGenome=b3822|UniProtKB=P15043	P15043	recQ	PTHR13710:SF105	DNA HELICASE RECQ FAMILY MEMBER	ATP-DEPENDENT DNA HELICASE RECQ	ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386	nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA recombination#GO:0006310;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152	intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165	DNA metabolism protein#PC00009;DNA helicase#PC00011	
ECOLI|EnsemblGenome=b0182|UniProtKB=P10441	P10441	lpxB	PTHR30372:SF7	LIPID-A-DISACCHARIDE SYNTHASE	LIPID-A-DISACCHARIDE SYNTHASE	glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758	glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;lipid A biosynthetic process#GO:0009245;liposaccharide metabolic process#GO:1903509;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610	extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transferase#PC00220	
ECOLI|EnsemblGenome=b2405|UniProtKB=P23841	P23841	xapR	PTHR30346:SF27	TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED	HTH-TYPE TRANSCRIPTIONAL REGULATOR XAPR	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889	protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991	winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b1245|UniProtKB=P0AFH6	P0AFH6	oppC	PTHR43386:SF2	OLIGOPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN APPC	OLIGOPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN OPPC	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b3340|UniProtKB=P0A6M8	P0A6M8	fusA	PTHR43261:SF8	TRANSLATION ELONGATION FACTOR G-RELATED	ELONGATION FACTOR G		cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component disassembly#GO:0022411;cellular component organization or biogenesis#GO:0071840;organelle disassembly#GO:1903008	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	translation elongation factor#PC00222;translation factor#PC00223;translational protein#PC00263	
ECOLI|EnsemblGenome=b2479|UniProtKB=P0A9I3	P0A9I3	gcvR	PTHR34875:SF5	UPF0237 PROTEIN MJ1558	GLYCINE CLEAVAGE SYSTEM TRANSCRIPTIONAL REPRESSOR		cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		
ECOLI|EnsemblGenome=b1120|UniProtKB=P75960	P75960	cobB	PTHR11085:SF4	NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED	NAD-DEPENDENT PROTEIN DEACYLASE					
ECOLI|EnsemblGenome=b4373|UniProtKB=P0A944	P0A944	rimI	PTHR43617:SF35	L-AMINO ACID N-ACETYLTRANSFERASE	[RIBOSOMAL PROTEIN BS18]-ALANINE N-ACETYLTRANSFERASE	N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;protein N-acyltransferase activity#GO:0140186;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096			acetyltransferase#PC00038	
ECOLI|EnsemblGenome=b3257|UniProtKB=P45566	P45566	yhdT	PTHR39174:SF1	INNER MEMBRANE PROTEIN-RELATED	MEMBRANE PROTEIN					
ECOLI|EnsemblGenome=b1981|UniProtKB=P76350	P76350	shiA	PTHR43045:SF8	SHIKIMATE TRANSPORTER	SHIKIMATE TRANSPORTER	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	carboxylic acid transmembrane transport#GO:1905039;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;organic hydroxy compound transport#GO:0015850;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b0615|UniProtKB=P75726	P75726	citF	PTHR40596:SF1	CITRATE LYASE ALPHA CHAIN	CITRATE LYASE ALPHA CHAIN		purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;acetyl-CoA metabolic process#GO:0006084;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086	catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535	lyase#PC00144;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2016|UniProtKB=P0AD12	P0AD12	yeeZ	PTHR48079:SF6	PROTEIN YEEZ	NAD-DEPENDENT EPIMERASE_DEHYDRATASE DOMAIN-CONTAINING PROTEIN	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029		cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2157|UniProtKB=P0ACR4	P0ACR4	yeiE	PTHR30126:SF39	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR YEIE	transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252		gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b3593|UniProtKB=P16916	P16916	rhsA	PTHR32305:SF18	FAMILY NOT NAMED	PROTEIN RHSA-RELATED					
ECOLI|EnsemblGenome=b0029|UniProtKB=P62623	P62623	ispH	PTHR30426:SF0	4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE	4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;carbohydrate derivative metabolic process#GO:1901135;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;isoprenoid metabolic process#GO:0006720;isoprenoid biosynthetic process#GO:0008299;glyceraldehyde-3-phosphate metabolic process#GO:0019682	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	reductase#PC00198;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3388|UniProtKB=P11557	P11557	damX	PTHR48233:SF5	MUCIN 4B, ISOFORM B-RELATED	BRINKER					
ECOLI|EnsemblGenome=b2905|UniProtKB=P27248	P27248	gcvT	PTHR43757:SF17	AMINOMETHYLTRANSFERASE	AMINOMETHYLTRANSFERASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741		intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	transferase#PC00220;methyltransferase#PC00155	
ECOLI|EnsemblGenome=b2118|UniProtKB=P33346	P33346	yehI	PTHR30634:SF16	OUTER MEMBRANE LOLAB LIPOPROTEIN INSERTION APPARATUS	OUTER-MEMBRANE LIPOPROTEIN LOLB				transporter#PC00227	
ECOLI|EnsemblGenome=b2573|UniProtKB=P0AGB6	P0AGB6	rpoE	PTHR43133:SF53	RNA POLYMERASE ECF-TYPE SIGMA FACTO	ECF RNA POLYMERASE SIGMA-E FACTOR	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789		helix-turn-helix transcription factor#PC00116;Sigma factor#PC00267;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b1861|UniProtKB=P0A809	P0A809	ruvA	PTHR33796:SF1	HOLLIDAY JUNCTION ATP-DEPENDENT DNA HELICASE RUVA	HOLLIDAY JUNCTION BRANCH MIGRATION COMPLEX SUBUNIT RUVA	isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657	response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;SOS response#GO:0009432;cellular process#GO:0009987;cellular response to stimulus#GO:0051716			
ECOLI|EnsemblGenome=b2830|UniProtKB=P0A776	P0A776	rppH	PTHR23114:SF27	M7GPPPN-MRNA HYDROLASE	RNA PYROPHOSPHOHYDROLASE		regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;RNA decapping#GO:0110154;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0123|UniProtKB=P36649	P36649	cueO	PTHR11709:SF549	MULTI-COPPER OXIDASE	MULTICOPPER OXIDASE CUEO	oxidoreductase activity, acting on metal ions#GO:0016722;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824		outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;periplasmic space#GO:0042597;extracellular region#GO:0005576	oxidase#PC00175	
ECOLI|EnsemblGenome=b3293|UniProtKB=P36677	P36677	yhdN	PTHR39158:SF1	OS08G0560600 PROTEIN	DNAJ HEAT SHOCK PROTEIN FAMILY (HSP40) MEMBER C28					
ECOLI|EnsemblGenome=b0146|UniProtKB=P0A823	P0A823	sfsA	PTHR30545:SF2	SUGAR FERMENTATION STIMULATION PROTEIN A	SUGAR FERMENTATION STIMULATION PROTEIN A	binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677			gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b1602|UniProtKB=P0AB67	P0AB67	pntB	PTHR44758:SF1	NAD(P) TRANSHYDROGENASE SUBUNIT BETA	NAD(P) TRANSHYDROGENASE SUBUNIT BETA	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075	export from cell#GO:0140352;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;monoatomic ion transport#GO:0006811;nucleotide metabolic process#GO:0009117;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;nucleobase-containing compound metabolic process#GO:0006139;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nucleobase-containing small molecule metabolic process#GO:0055086;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;generation of precursor metabolites and energy#GO:0006091;transport#GO:0006810;metabolic process#GO:0008152	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b3426|UniProtKB=P13035	P13035	glpD	PTHR11985:SF35	GLYCEROL-3-PHOSPHATE DEHYDROGENASE	AEROBIC GLYCEROL-3-PHOSPHATE DEHYDROGENASE	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614	phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;metabolic process#GO:0008152;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135		dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b2424|UniProtKB=P16701	P16701	cysU	PTHR30406:SF10	SULFATE TRANSPORT SYSTEM PERMEASE PROTEIN	SULFATE TRANSPORT SYSTEM PERMEASE PROTEIN CYST			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b1703|UniProtKB=P0A8A4	P0A8A4	ppsR	PTHR31756:SF3	PYRUVATE, PHOSPHATE DIKINASE REGULATORY PROTEIN 1, CHLOROPLASTIC	PYRUVATE, PHOSPHATE DIKINASE REGULATORY PROTEIN 1, CHLOROPLASTIC	catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphatase activity#GO:0016791;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;phosphoprotein phosphatase activity#GO:0004721			protein-binding activity modulator#PC00095;kinase modulator#PC00140	
ECOLI|EnsemblGenome=b3093|UniProtKB=P0AA78	P0AA78	exuT	PTHR11662:SF285	SOLUTE CARRIER FAMILY 17	HEXURONATE TRANSPORTER	sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215			secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b1622|UniProtKB=P23256	P23256	malY	PTHR43525:SF1	PROTEIN MALY	PROTEIN MALY	carbon-sulfur lyase activity#GO:0016846;lyase activity#GO:0016829;catalytic activity#GO:0003824			metabolite interconversion enzyme#PC00262;transaminase#PC00216	
ECOLI|EnsemblGenome=b1507|UniProtKB=P23874	P23874	hipA	PTHR37419:SF1	SERINE/THREONINE-PROTEIN KINASE TOXIN HIPA	SERINE_THREONINE-PROTEIN KINASE TOXIN HIPA	protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824		cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	non-receptor serine/threonine protein kinase#PC00167	
ECOLI|EnsemblGenome=b2946|UniProtKB=P0AGL7	P0AGL7	rsmE	PTHR30027:SF3	RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE E	16S RRNA (URACIL(1498)-N(3))-METHYLTRANSFERASE	catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a rRNA#GO:0140102;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757	nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;methylation#GO:0032259;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA methylation#GO:0031167;macromolecule biosynthetic process#GO:0009059;rRNA base methylation#GO:0070475;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467		RNA metabolism protein#PC00031;RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b4395|UniProtKB=P0A7A2	P0A7A2	gpmB	PTHR48100:SF68	BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED	PHOSPHOGLYCERATE MUTASE GPMB-RELATED	phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578		cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	phosphatase#PC00181;hydrolase#PC00121	
ECOLI|EnsemblGenome=b2791|UniProtKB=P0AA41	P0AA41	truC	PTHR21600:SF56	MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE	TRNA PSEUDOURIDINE SYNTHASE C	isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866	nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA modification#GO:0000154;pseudouridine synthesis#GO:0001522;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774		RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b4116|UniProtKB=P33234	P33234	adiY	PTHR43280:SF20	ARAC-FAMILY TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR ADIY-RELATED	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690	regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252		DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b3451|UniProtKB=P10906	P10906	ugpE	PTHR43744:SF8	ABC TRANSPORTER PERMEASE PROTEIN MG189-RELATED-RELATED	SN-GLYCEROL-3-PHOSPHATE TRANSPORT SYSTEM PERMEASE PROTEIN UGPE	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505		cellular anatomical structure#GO:0110165;membrane#GO:0016020	ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227	
ECOLI|EnsemblGenome=b2795|UniProtKB=P0ADR8	P0ADR8	ppnN	PTHR43393:SF1	CYTOKININ RIBOSIDE 5'-MONOPHOSPHATE PHOSPHORIBOHYDROLASE	PYRIMIDINE_PURINE NUCLEOTIDE 5'-MONOPHOSPHATE NUCLEOSIDASE	catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b0511|UniProtKB=P75712	P75712	ybbW	PTHR30618:SF20	NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER	ALLANTOIN PERMEASE-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	cellular process#GO:0009987;transport#GO:0006810;nitrogen compound transport#GO:0071705;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b2836|UniProtKB=P31119	P31119	aas	PTHR43272:SF33	LONG-CHAIN-FATTY-ACID--COA LIGASE	LONG CHAIN ACYL-COA SYNTHETASE 6, PEROXISOMAL	ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824		membrane#GO:0016020;cellular anatomical structure#GO:0110165	ligase#PC00142	
ECOLI|EnsemblGenome=b0431|UniProtKB=P0ABI8	P0ABI8	cyoB	PTHR10422:SF35	CYTOCHROME C OXIDASE SUBUNIT 1	CYTOCHROME BO(3) UBIQUINOL OXIDASE SUBUNIT 1	monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824	aerobic respiration#GO:0009060;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;cellular respiration#GO:0045333;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;generation of precursor metabolites and energy#GO:0006091;transport#GO:0006810;metabolic process#GO:0008152;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;energy derivation by oxidation of organic compounds#GO:0015980	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	oxidase#PC00175;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3990|UniProtKB=P30140	P30140	thiH	PTHR43583:SF1	2-IMINOACETATE SYNTHASE	2-IMINOACETATE SYNTHASE	lyase activity#GO:0016829;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830	small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;organophosphate biosynthetic process#GO:0090407;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283	protein-containing complex#GO:0032991;catalytic complex#GO:1902494	metabolite interconversion enzyme#PC00262;lyase#PC00144	
ECOLI|EnsemblGenome=b0043|UniProtKB=P68644	P68644	fixC	PTHR43624:SF1	ELECTRON TRANSFER FLAVOPROTEIN-QUINONE OXIDOREDUCTASE YDIS-RELATED	PROTEIN FIXC		carnitine metabolic process#GO:0009437;cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575		oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2485|UniProtKB=P0AEW1	P0AEW1	hyfE	PTHR38601:SF1	HYDROGENASE-4 COMPONENT E	HYDROGENASE-4 COMPONENT E					
ECOLI|EnsemblGenome=b2713|UniProtKB=P0AAK4	P0AAK4	hydN	PTHR42859:SF17	OXIDOREDUCTASE	ELECTRON TRANSPORT PROTEIN HYDN-RELATED				metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1225|UniProtKB=P11349	P11349	narH	PTHR43518:SF1	NITRATE REDUCTASE BETA SUBUNIT	RESPIRATORY NITRATE REDUCTASE 1 BETA CHAIN	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900;anaerobic electron transport chain#GO:0019645;anaerobic respiration#GO:0009061	cellular anatomical structure#GO:0110165;membrane#GO:0016020	reductase#PC00198;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1224|UniProtKB=P09152	P09152	narG	PTHR43105:SF2	RESPIRATORY NITRATE REDUCTASE	RESPIRATORY NITRATE REDUCTASE 1 ALPHA CHAIN			membrane#GO:0016020;cellular anatomical structure#GO:0110165	reductase#PC00198;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3441|UniProtKB=P46854	P46854	aaaT	PTHR43617:SF22	L-AMINO ACID N-ACETYLTRANSFERASE	L-AMINO ACID N-ACETYLTRANSFERASE AAAT	transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747			acetyltransferase#PC00038	
ECOLI|EnsemblGenome=b1589|UniProtKB=P0AAJ1	P0AAJ1	ynfG	PTHR43177:SF5	PROTEIN NRFC	ANAEROBIC DIMETHYL SULFOXIDE REDUCTASE CHAIN B-RELATED	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667	metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;electron transport chain#GO:0022900;sulfur compound metabolic process#GO:0006790;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;anaerobic respiration#GO:0009061;anaerobic electron transport chain#GO:0019645		oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3872|UniProtKB=P0ACM9	P0ACM9	yihL	PTHR44846:SF7	MANNOSYL-D-GLYCERATE TRANSPORT/METABOLISM SYSTEM REPRESSOR MNGR-RELATED	TRANSCRIPTIONAL REGULATOR OF 2-AMINOETHYLPHOSPHONATE DEGRADATION OPERONS-RELATED		negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219		helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b3905|UniProtKB=P09377	P09377	rhaS	PTHR43280:SF28	ARAC-FAMILY TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL ACTIVATOR RHAS	sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676	regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355		helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b1462|UniProtKB=P76121	P76121	yddH	PTHR43567:SF1	FLAVOREDOXIN-RELATED-RELATED	LMO1050 PROTEIN				oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0070|UniProtKB=P31675	P31675	setA	PTHR23535:SF2	SUGAR EFFLUX TRANSPORTER A-RELATED	SUGAR EFFLUX TRANSPORTER A-RELATED	carbohydrate transmembrane transporter activity#GO:0015144;monoatomic cation transmembrane transporter activity#GO:0008324;solute:proton symporter activity#GO:0015295;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291	carbohydrate transport#GO:0008643;cellular response to stress#GO:0033554;transport#GO:0006810;cellular response to chemical stimulus#GO:0070887;cellular response to chemical stress#GO:0062197;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;D-glucose transmembrane transport#GO:1904659;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;response to stimulus#GO:0050896;response to chemical#GO:0042221;carbohydrate transmembrane transport#GO:0034219	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b4263|UniProtKB=P39342	P39342	yjgR	PTHR30121:SF6	UNCHARACTERIZED PROTEIN YJGR-RELATED	TRAG FAMILY PROTEIN					
ECOLI|EnsemblGenome=b4319|UniProtKB=P08190	P08190	fimG	PTHR33420:SF27	FIMBRIAL SUBUNIT ELFA-RELATED	PROTEIN FIMG		cell-substrate adhesion#GO:0031589;single-species biofilm formation#GO:0044010;cell adhesion#GO:0007155;cellular process#GO:0009987	cell projection#GO:0042995;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2300|UniProtKB=P67095	P67095	yfcE	PTHR11124:SF26	VACUOLAR SORTING PROTEIN VPS29	PHOSPHODIESTERASE YFCE	phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788		cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	vesicle coat protein#PC00235	
ECOLI|EnsemblGenome=b0912|UniProtKB=P0A6Y1	P0A6Y1	ihfB	PTHR33175:SF5	DNA-BINDING PROTEIN HU	INTEGRATION HOST FACTOR SUBUNIT BETA	DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522	bacterial nucleoid#GO:0043590;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoid#GO:0009295;protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b0880|UniProtKB=P0A968	P0A968	cspD	PTHR11544:SF141	COLD SHOCK DOMAIN CONTAINING PROTEINS	COLD SHOCK-LIKE PROTEIN CSPD					
ECOLI|EnsemblGenome=b0823|UniProtKB=P75793	P75793	ybiW	PTHR43641:SF2	FORMATE ACETYLTRANSFERASE 3-RELATED	DEHYDRATASE YBIW-RELATED			cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	transferase#PC00220;acetyltransferase#PC00038	
ECOLI|EnsemblGenome=b4080|UniProtKB=P32714	P32714	mdtP	PTHR30203:SF20	OUTER MEMBRANE CATION EFFLUX PROTEIN	MULTIDRUG RESISTANCE OUTER MEMBRANE PROTEIN MDTP-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;membrane#GO:0016020		
ECOLI|EnsemblGenome=b0780|UniProtKB=P75767	P75767	ybhK	PTHR30135:SF3	UNCHARACTERIZED PROTEIN YVCK-RELATED	GLUCONEOGENESIS FACTOR-RELATED					
ECOLI|EnsemblGenome=b0136|UniProtKB=P37016	P37016	yadK	PTHR33420:SF5	FIMBRIAL SUBUNIT ELFA-RELATED	FIMBRIAL SUBUNIT		cell adhesion#GO:0007155;cellular process#GO:0009987;single-species biofilm formation#GO:0044010;cell-substrate adhesion#GO:0031589	cell projection#GO:0042995;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2796|UniProtKB=P0AAD6	P0AAD6	sdaC	PTHR35334:SF2	SERINE TRANSPORTER	SERINE TRANSPORTER SDAC	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;amino acid transport#GO:0006865	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b1206|UniProtKB=P0AFR2	P0AFR2	dauA	PTHR11814:SF215	SULFATE TRANSPORTER	C4-DICARBOXYLIC ACID TRANSPORTER DAUA	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b1901|UniProtKB=P02924	P02924	araF	PTHR30036:SF6	D-XYLOSE-BINDING PERIPLASMIC PROTEIN	L-ARABINOSE-BINDING PERIPLASMIC PROTEIN	carbohydrate binding#GO:0030246;binding#GO:0005488		periplasmic space#GO:0042597;extracellular region#GO:0005576;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313		
ECOLI|EnsemblGenome=b4013|UniProtKB=P07623	P07623	metAS	PTHR20919:SF0	HOMOSERINE O-SUCCINYLTRANSFERASE	HOMOSERINE O-SUCCINYLTRANSFERASE	acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747			transferase#PC00220	Methionine biosynthesis#P02753>Homoserine succinyltransferase#P03023
ECOLI|EnsemblGenome=b1484|UniProtKB=P77268	P77268	ddpD	PTHR43297:SF7	OLIGOPEPTIDE TRANSPORT ATP-BINDING PROTEIN APPD	D,D-DIPEPTIDE TRANSPORT ATP-BINDING PROTEIN DDPD-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate derivative transmembrane transporter activity#GO:1901505			ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227	
ECOLI|EnsemblGenome=b2704|UniProtKB=P05706	P05706	srlB	PTHR40398:SF1	PTS SYSTEM GLUCITOL/SORBITOL-SPECIFIC EIIA COMPONENT	PTS SYSTEM GLUCITOL_SORBITOL-SPECIFIC EIIA COMPONENT	catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772				
ECOLI|EnsemblGenome=b0582|UniProtKB=P0CF92	P0CF92	insL2	PTHR33258:SF1	TRANSPOSASE INSL FOR INSERTION SEQUENCE ELEMENT IS186A-RELATED	TRANSPOSASE INSL FOR INSERTION SEQUENCE ELEMENT IS186A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b1651|UniProtKB=P0AC81	P0AC81	gloA	PTHR46036:SF24	LACTOYLGLUTATHIONE LYASE	LACTOYLGLUTATHIONE LYASE	lyase activity#GO:0016829;carbon-sulfur lyase activity#GO:0016846;catalytic activity#GO:0003824	cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;response to chemical#GO:0042221;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;aldehyde catabolic process#GO:0046185;metabolic process#GO:0008152;cellular detoxification of aldehyde#GO:0110095;ketone metabolic process#GO:0042180;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;response to toxic substance#GO:0009636;small molecule catabolic process#GO:0044282;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	lyase#PC00144;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2608|UniProtKB=P0A7X6	P0A7X6	rimM	PTHR33692:SF1	RIBOSOME MATURATION FACTOR RIMM	RIBOSOME MATURATION FACTOR RIMM		RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b2565|UniProtKB=P0A7H3	P0A7H3	recO	PTHR33991:SF1	DNA REPAIR PROTEIN RECO	DNA REPAIR PROTEIN RECO		response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554	membraneless organelle#GO:0043228;bacterial nucleoid#GO:0043590;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoid#GO:0009295;intracellular membraneless organelle#GO:0043232	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b1775|UniProtKB=P76230	P76230	ydjK	PTHR24064:SF605	SOLUTE CARRIER FAMILY 22 MEMBER	INNER MEMBRANE METABOLITE TRANSPORT PROTEIN YDJE-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b2777|UniProtKB=P64554	P64554	queE	PTHR42836:SF1	7-CARBOXY-7-DEAZAGUANINE SYNTHASE	7-CARBOXY-7-DEAZAGUANINE SYNTHASE	catalytic activity#GO:0003824;lyase activity#GO:0016829	cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA wobble base modification#GO:0002097;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412			
ECOLI|EnsemblGenome=b4040|UniProtKB=P0AGK1	P0AGK1	ubiA	PTHR11048:SF43	PRENYLTRANSFERASES	4-HYDROXYBENZOATE OCTAPRENYLTRANSFERASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659	biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;ketone metabolic process#GO:0042180;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	metabolite interconversion enzyme#PC00262;acyltransferase#PC00042	
ECOLI|EnsemblGenome=b3505|UniProtKB=P0CE58	P0CE58	insH11	PTHR35604:SF2	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097	nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b2595|UniProtKB=P0AC02	P0AC02	bamD	PTHR37423:SF1	SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE-RELATED	OUTER MEMBRANE PROTEIN ASSEMBLY FACTOR BAMD		localization within membrane#GO:0051668;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular component organization#GO:0016043;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;membrane#GO:0016020;cell outer membrane#GO:0009279;membrane protein complex#GO:0098796;external encapsulating structure#GO:0030312;side of membrane#GO:0098552;extracellular region#GO:0005576;outer membrane#GO:0019867;extracellular protein-containing complex#GO:0140392		
ECOLI|EnsemblGenome=b2952|UniProtKB=P64564	P64564	yggT	PTHR33219:SF14	YLMG HOMOLOG PROTEIN 2, CHLOROPLASTIC	PROTEIN COFACTOR ASSEMBLY OF COMPLEX C SUBUNIT B CCB3, CHLOROPLASTIC					
ECOLI|EnsemblGenome=b4180|UniProtKB=P63177	P63177	rlmB	PTHR46429:SF3	23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB	23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB	catalytic activity, acting on a rRNA#GO:0140102;O-methyltransferase activity#GO:0008171;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on RNA#GO:0140098;rRNA (guanine) methyltransferase activity#GO:0016435;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741				
ECOLI|EnsemblGenome=b2169|UniProtKB=P69811	P69811	fruB	PTHR30181:SF3	MANNITOL PERMEASE IIC COMPONENT	MULTIPHOSPHORYL TRANSFER PROTEIN	carbohydrate transmembrane transporter activity#GO:0015144;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein-phosphocysteine-sugar phosphotransferase activity#GO:0090563;active transmembrane transporter activity#GO:0022804;sugar transmembrane transporter activity#GO:0051119;transferase activity, transferring phosphorus-containing groups#GO:0016772;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transferase activity#GO:0016740;catalytic activity#GO:0003824	transport#GO:0006810;carbohydrate transport#GO:0008643;establishment of localization#GO:0051234;import into cell#GO:0098657;transmembrane transport#GO:0055085;localization#GO:0051179;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739	transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991		
ECOLI|EnsemblGenome=b3942|UniProtKB=P13029	P13029	katG	PTHR30555:SF0	HYDROPEROXIDASE I, BIFUNCTIONAL CATALASE-PEROXIDASE	CATALASE-PEROXIDASE	binding#GO:0005488;tetrapyrrole binding#GO:0046906;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;heme binding#GO:0020037;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;catabolic process#GO:0009056;hydrogen peroxide metabolic process#GO:0042743;cellular response to stimulus#GO:0051716;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;response to reactive oxygen species#GO:0000302;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to stress#GO:0006950;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	metabolite interconversion enzyme#PC00262;peroxidase#PC00180	
ECOLI|EnsemblGenome=b2972|UniProtKB=Q46836	Q46836	pppA	PTHR30487:SF0	TYPE 4 PREPILIN-LIKE PROTEINS LEADER PEPTIDE-PROCESSING ENZYME	PREPILIN LEADER PEPTIDASE_N-METHYLTRANSFERASE-RELATED	catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	protein modifying enzyme#PC00260;aspartic protease#PC00053	
ECOLI|EnsemblGenome=b2168|UniProtKB=P0AEW9	P0AEW9	fruK	PTHR46566:SF5	1-PHOSPHOFRUCTOKINASE-RELATED	1-PHOSPHOFRUCTOKINASE	phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;carbohydrate kinase activity#GO:0019200		cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	transferase#PC00220;kinase#PC00137	
ECOLI|Gene_OrderedLocusName=JW0226|UniProtKB=P28369	P28369	prfH	PTHR43804:SF9	LD18447P	PEPTIDE CHAIN RELEASE FACTOR HOMOLOG-RELATED				translation release factor#PC00225;translation factor#PC00223;translational protein#PC00263	
ECOLI|EnsemblGenome=b1521|UniProtKB=P0A6L7	P0A6L7	uxaB	PTHR30524:SF0	MANNITOL-1-PHOSPHATE 5-DEHYDROGENASE	ALTRONATE OXIDOREDUCTASE-RELATED	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2301|UniProtKB=P77544	P77544	yfcF	PTHR42673:SF21	MALEYLACETOACETATE ISOMERASE	GLUTATHIONE S-TRANSFERASE YFCF	transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740;glutathione transferase activity#GO:0004364;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;glutathione metabolic process#GO:0006749;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987		isomerase#PC00135	
ECOLI|EnsemblGenome=b3160|UniProtKB=P0ADV5	P0ADV5	yhbW	PTHR30137:SF6	LUCIFERASE-LIKE MONOOXYGENASE	LUCIFERASE-LIKE MONOOXYGENASE			cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	oxidoreductase#PC00176;oxygenase#PC00177	
ECOLI|EnsemblGenome=b2767|UniProtKB=Q46905	Q46905	ygcO	PTHR43082:SF1	FERREDOXIN-LIKE	FERREDOXIN-LIKE PROTEIN FIXX-RELATED				oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3679|UniProtKB=P31448	P31448	yidK	PTHR11819:SF195	SOLUTE CARRIER FAMILY 5	SODIUM_GLUCOSE COTRANSPORTER	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	secondary carrier transporter#PC00258;transporter#PC00227	
ECOLI|EnsemblGenome=b1702|UniProtKB=P23538	P23538	ppsA	PTHR43030:SF1	PHOSPHOENOLPYRUVATE SYNTHASE	PHOSPHOENOLPYRUVATE SYNTHASE	transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740	cellular process#GO:0009987;gluconeogenesis#GO:0006094;hexose biosynthetic process#GO:0019319;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate biosynthetic process#GO:0016051;monosaccharide biosynthetic process#GO:0046364;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;glucose metabolic process#GO:0006006		transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3208|UniProtKB=P46022	P46022	mtgA	PTHR30400:SF0	MONOFUNCTIONAL BIOSYNTHETIC PEPTIDOGLYCAN TRANSGLYCOSYLASE	BIOSYNTHETIC PEPTIDOGLYCAN TRANSGLYCOSYLASE	glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758	aminoglycan metabolic process#GO:0006022;cell wall biogenesis#GO:0042546;cell wall macromolecule metabolic process#GO:0044036;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan metabolic process#GO:0030203;peptidoglycan biosynthetic process#GO:0009252;metabolic process#GO:0008152;peptidoglycan metabolic process#GO:0000270;peptidoglycan-based cell wall biogenesis#GO:0009273;glycosaminoglycan biosynthetic process#GO:0006024;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;carbohydrate derivative biosynthetic process#GO:1901137;cellular component biogenesis#GO:0044085;cell wall macromolecule biosynthetic process#GO:0044038;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cell wall organization or biogenesis#GO:0071554;biosynthetic process#GO:0009058	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	glycosyltransferase#PC00111	
ECOLI|EnsemblGenome=b3499|UniProtKB=P37634	P37634	rlmJ	PTHR37426:SF1	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J	N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173	nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;rRNA base methylation#GO:0070475;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b2343|UniProtKB=P0AD33	P0AD33	yfcZ	PTHR38769:SF1	UPF0381 PROTEIN YFCZ-RELATED	UPF0381 PROTEIN YFCZ-RELATED			intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b1501|UniProtKB=P77561	P77561	ydeP	PTHR43105:SF4	RESPIRATORY NITRATE REDUCTASE	PROTEIN YDEP			membrane#GO:0016020;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176;reductase#PC00198	
ECOLI|EnsemblGenome=b3126|UniProtKB=P23522	P23522	garL	PTHR30502:SF4	2-KETO-3-DEOXY-L-RHAMNONATE ALDOLASE	5-KETO-4-DEOXY-D-GLUCARATE ALDOLASE	catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832			lyase#PC00144;aldolase#PC00044;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1686|UniProtKB=P77781	P77781	menI	PTHR43240:SF28	1,4-DIHYDROXY-2-NAPHTHOYL-COA THIOESTERASE 1	1,4-DIHYDROXY-2-NAPHTHOYL-COA HYDROLASE	hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;acyl-CoA hydrolase activity#GO:0016289;catalytic activity#GO:0003824;deacylase activity#GO:0160215	small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;biosynthetic process#GO:0009058;menaquinone biosynthetic process#GO:0009234;small molecule metabolic process#GO:0044281;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ketone metabolic process#GO:0042180	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	metabolite interconversion enzyme#PC00262;esterase#PC00097	
ECOLI|EnsemblGenome=b1502|UniProtKB=P77588	P77588	ydeQ	PTHR33420:SF14	FIMBRIAL SUBUNIT ELFA-RELATED	TYPE 1 FIMBRIN D-MANNOSE SPECIFIC ADHESIN		single-species biofilm formation#GO:0044010;cellular process#GO:0009987;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589	cellular anatomical structure#GO:0110165;cell projection#GO:0042995		
ECOLI|EnsemblGenome=b2744|UniProtKB=P0A840	P0A840	surE	PTHR30457:SF12	5'-NUCLEOTIDASE SURE	5'_3'-NUCLEOTIDASE SURE	hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;5'-nucleotidase activity#GO:0008253;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;hydrolase activity, acting on acid anhydrides#GO:0016817;phosphatase activity#GO:0016791				
ECOLI|EnsemblGenome=b4244|UniProtKB=P0A7F3	P0A7F3	pyrI	PTHR35805:SF1	ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN	ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN		nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;pyrimidine nucleobase metabolic process#GO:0006206;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;primary metabolic process#GO:0044238	transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991	protein-binding activity modulator#PC00095	De novo pyrimidine ribonucleotides biosythesis#P02740>Aspartate carbamoyltransferase#P02926
ECOLI|Gene_OrderedLocusName=b4462|UniProtKB=P76616	P76616	ygaQ	PTHR43447:SF58	ALPHA-AMYLASE	CYTOPLASMIC ALPHA-AMYLASE	hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553			amylase#PC00048	
ECOLI|EnsemblGenome=b0312|UniProtKB=P17445	P17445	betB	PTHR11699:SF309	ALDEHYDE DEHYDROGENASE-RELATED	BETAINE ALDEHYDE DEHYDROGENASE	oxidoreductase activity#GO:0016491;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824		intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402
ECOLI|EnsemblGenome=b2204|UniProtKB=P33934	P33934	napH	PTHR30176:SF3	FERREDOXIN-TYPE PROTEIN NAPH	FERREDOXIN-TYPE PROTEIN NAPH			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transfer/carrier protein#PC00219	
ECOLI|EnsemblGenome=b2983|UniProtKB=Q46841	Q46841	yghQ	PTHR30250:SF11	PST FAMILY PREDICTED COLANIC ACID TRANSPORTER	INNER MEMBRANE PROTEIN YGHQ-RELATED			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b2495|UniProtKB=P76569	P76569	yfgD	PTHR30041:SF4	ARSENATE REDUCTASE	ARSENATE REDUCTASE				reductase#PC00198	
ECOLI|EnsemblGenome=b1112|UniProtKB=P0AB40	P0AB40	bhsA	PTHR34156:SF10	OUTER MEMBRANE PROTEIN-RELATED-RELATED	MULTIPLE STRESS RESISTANCE PROTEIN BHSA		response to stimulus#GO:0050896;response to stress#GO:0006950			
ECOLI|EnsemblGenome=b3116|UniProtKB=P0AAD8	P0AAD8	tdcC	PTHR35334:SF1	SERINE TRANSPORTER	THREONINE_SERINE TRANSPORTER TDCC	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	localization#GO:0051179;establishment of localization#GO:0051234;amino acid transport#GO:0006865;transport#GO:0006810	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b2710|UniProtKB=Q46877	Q46877	norV	PTHR43717:SF1	ANAEROBIC NITRIC OXIDE REDUCTASE FLAVORUBREDOXIN	ANAEROBIC NITRIC OXIDE REDUCTASE FLAVORUBREDOXIN	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1236|UniProtKB=P0AEP3	P0AEP3	galU	PTHR43197:SF1	UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE	UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE	nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772	carbohydrate metabolic process#GO:0005975;lipopolysaccharide core region biosynthetic process#GO:0009244;lipopolysaccharide biosynthetic process#GO:0009103;liposaccharide metabolic process#GO:1903509;polysaccharide metabolic process#GO:0005976;primary metabolic process#GO:0044238;lipopolysaccharide metabolic process#GO:0008653;oligosaccharide biosynthetic process#GO:0009312;polysaccharide biosynthetic process#GO:0000271;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;lipid biosynthetic process#GO:0008610;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;oligosaccharide metabolic process#GO:0009311;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;lipid metabolic process#GO:0006629;metabolic process#GO:0008152	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;nucleotidyltransferase#PC00174	
ECOLI|EnsemblGenome=b0541|UniProtKB=P0CF81	P0CF81	insF3	PTHR42648:SF5	TRANSPOSASE, PUTATIVE-RELATED	TRANSPOSASE INSF FOR INSERTION SEQUENCE IS3A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b2042|UniProtKB=P0AAB6	P0AAB6	galF	PTHR43197:SF2	UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE	UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE	nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772	carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;oligosaccharide metabolic process#GO:0009311;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;oligosaccharide biosynthetic process#GO:0009312;lipopolysaccharide metabolic process#GO:0008653;polysaccharide biosynthetic process#GO:0000271;polysaccharide metabolic process#GO:0005976;liposaccharide metabolic process#GO:1903509;lipopolysaccharide core region biosynthetic process#GO:0009244;lipopolysaccharide biosynthetic process#GO:0009103;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	nucleotidyltransferase#PC00174;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3791|UniProtKB=P27833	P27833	wecE	PTHR30244:SF43	TRANSAMINASE	DTDP-4-AMINO-4,6-DIDEOXYGALACTOSE TRANSAMINASE	heterocyclic compound binding#GO:1901363;transferase activity#GO:0016740;catalytic activity#GO:0003824;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;transaminase activity#GO:0008483	macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;polysaccharide metabolic process#GO:0005976;polysaccharide biosynthetic process#GO:0000271;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170		transaminase#PC00216	
ECOLI|EnsemblGenome=b2611|UniProtKB=P64432	P64432	ypjD	PTHR38034:SF1	INNER MEMBRANE PROTEIN YPJD	INNER MEMBRANE PROTEIN YPJD					
ECOLI|EnsemblGenome=b0755|UniProtKB=P62707	P62707	gpmA	PTHR11931:SF33	PHOSPHOGLYCERATE MUTASE	PHOSPHOGLYCERATE MUTASE	phosphoglycerate mutase activity#GO:0004619;isomerase activity#GO:0016853;intramolecular phosphotransferase activity#GO:0016868;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824	purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;ADP catabolic process#GO:0046032;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	mutase#PC00160;isomerase#PC00135	Glycolysis#P00024>Phosphoglyceromutase#P00680
ECOLI|EnsemblGenome=b3643|UniProtKB=P0CG19	P0CG19	rph	PTHR11953:SF3	EXOSOME COMPLEX COMPONENT	TRUNCATED INACTIVE RIBONUCLEASE PH	RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488	primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;rRNA metabolic process#GO:0016072;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170		RNA metabolism protein#PC00031;exoribonuclease#PC00099	
ECOLI|EnsemblGenome=b3292|UniProtKB=P0ACS5	P0ACS5	zntR	PTHR30204:SF92	REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR	HTH-TYPE TRANSCRIPTIONAL REGULATOR ZNTR	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255		helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b1473|UniProtKB=P46136	P46136	yddG	PTHR42920:SF24	OS03G0707200 PROTEIN-RELATED	AROMATIC AMINO ACID EXPORTER YDDG	aromatic amino acid transmembrane transporter activity#GO:0015173;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171	amino acid transport#GO:0006865;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;cellular process#GO:0009987;export from cell#GO:0140352	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b1920|UniProtKB=P0AEM9	P0AEM9	tcyJ	PTHR35936:SF35	MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE F	L-CYSTINE-BINDING PROTEIN TCYJ					
ECOLI|EnsemblGenome=b2661|UniProtKB=P25526	P25526	gabD	PTHR43353:SF15	SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL	LACTALDEHYDE DEHYDROGENASE-RELATED	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029	oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176	Gamma-aminobutyric acid synthesis#P04384>Succinic semialdehyde dehydrogenase#P04481
ECOLI|EnsemblGenome=b0512|UniProtKB=P77671	P77671	allB	PTHR43668:SF4	ALLANTOINASE	ALLANTOINASE	catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787	purine nucleobase catabolic process#GO:0006145;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	hydrolase#PC00121	De novo pyrimidine ribonucleotides biosythesis#P02740>Dihydroorotase#P02928;Allantoin degradation#P02725>Allantoinase#P02822
ECOLI|EnsemblGenome=b2217|UniProtKB=P0DMC7	P0DMC7	rcsB	PTHR43214:SF17	TWO-COMPONENT RESPONSE REGULATOR	TRANSCRIPTIONAL REGULATORY PROTEIN RCSB	double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255		winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b0360|UniProtKB=P0CF40	P0CF40	insC1	PTHR37936:SF3	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b0357|UniProtKB=P0AAP3	P0AAP3	frmR	PTHR33677:SF5	TRANSCRIPTIONAL REPRESSOR FRMR-RELATED	TRANSCRIPTIONAL REPRESSOR FRMR	transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription repressor activity#GO:0001217;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890	protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993	gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b3064|UniProtKB=P05852	P05852	tsaD	PTHR11735:SF16	TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE	TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE				RNA metabolism protein#PC00031;RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b1258|UniProtKB=P21362	P21362	yciF	PTHR30565:SF9	PROTEIN YCIF	PROTEIN YCIF					
ECOLI|EnsemblGenome=b4044|UniProtKB=P28303	P28303	dinF	PTHR42893:SF58	PROTEIN DETOXIFICATION 44, CHLOROPLASTIC-RELATED	DNA DAMAGE-INDUCIBLE PROTEIN F	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b2778|UniProtKB=P55140	P55140	ygcG	PTHR30373:SF2	UPF0603 PROTEIN YGCG	UPF0603 PROTEIN YGCG					
ECOLI|EnsemblGenome=b0476|UniProtKB=P23872	P23872	aes	PTHR23024:SF176	ARYLACETAMIDE DEACETYLASE	ACETYL ESTERASE	catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787			deacetylase#PC00087	
ECOLI|Gene_OrderedLocusName=JW0247|UniProtKB=P75680	P75680	insO1	PTHR46889:SF8	TRANSPOSASE INSF FOR INSERTION SEQUENCE IS3B-RELATED	TRANSPOSASE INSO FOR INSERTION SEQUENCE ELEMENT IS911A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b2155|UniProtKB=P17315	P17315	cirA	PTHR30069:SF53	TONB-DEPENDENT OUTER MEMBRANE RECEPTOR	COLICIN I RECEPTOR	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;siderophore-iron transmembrane transporter activity#GO:0015343	iron coordination entity transport#GO:1901678;transition metal ion transport#GO:0000041;transport#GO:0006810;iron ion transport#GO:0006826;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001	cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;cell outer membrane#GO:0009279;membrane#GO:0016020;external encapsulating structure#GO:0030312;outer membrane#GO:0019867;extracellular region#GO:0005576		
ECOLI|EnsemblGenome=b1767|UniProtKB=P0A962	P0A962	ansA	PTHR11707:SF28	L-ASPARAGINASE	60 KDA LYSOPHOSPHOLIPASE	hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;amidase activity#GO:0004040;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811				
ECOLI|EnsemblGenome=b3088|UniProtKB=P42601	P42601	alx	PTHR30238:SF8	MEMBRANE BOUND PREDICTED REDOX MODULATOR	MANGANESE EXPORTER ALX		response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to environmental stimulus#GO:0104004;cellular response to abiotic stimulus#GO:0071214;response to stimulus#GO:0050896	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b2291|UniProtKB=P76491	P76491	yfbR	PTHR11845:SF13	5'-DEOXYNUCLEOTIDASE HDDC2	5'-DEOXYNUCLEOTIDASE HDDC2	catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787		cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		
ECOLI|EnsemblGenome=b1102|UniProtKB=P16869	P16869	fhuE	PTHR32552:SF93	FERRICHROME IRON RECEPTOR-RELATED	HYDROXAMATE SIDEROPHORE RECEPTOR FHUE	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;siderophore-iron transmembrane transporter activity#GO:0015343	iron import into cell#GO:0033212;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular localization#GO:0051641;siderophore-dependent iron import pathway#GO:0180060;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;siderophore-iron import into cell#GO:0033214;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;iron coordination entity transport#GO:1901678;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;import into cell#GO:0098657;establishment of localization#GO:0051234	membrane#GO:0016020;cell outer membrane#GO:0009279;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;outer membrane#GO:0019867;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313		
ECOLI|EnsemblGenome=b3558|UniProtKB=P19769	P19769	insK	PTHR42648:SF11	TRANSPOSASE, PUTATIVE-RELATED	TRANSPOSON TY4-P GAG-POL POLYPROTEIN				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b1298|UniProtKB=P76038	P76038	puuD	PTHR43235:SF12	GLUTAMINE AMIDOTRANSFERASE PB2B2.05-RELATED	GAMMA-GLUTAMYL-GAMMA-AMINOBUTYRATE HYDROLASE PUUD	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811	polyamine catabolic process#GO:0006598;metabolic process#GO:0008152;amine catabolic process#GO:0009310;catabolic process#GO:0009056;biogenic amine metabolic process#GO:0006576;amine metabolic process#GO:0009308;cellular process#GO:0009987;polyamine metabolic process#GO:0006595		cysteine protease#PC00081;protease#PC00190	
ECOLI|EnsemblGenome=b1681|UniProtKB=P77689	P77689	sufD	PTHR43575:SF1	PROTEIN ABCI7, CHLOROPLASTIC	IRON-SULFUR CLUSTER ASSEMBLY PROTEIN SUFD		cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;iron-sulfur cluster assembly#GO:0016226;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b3481|UniProtKB=P0A6Z6	P0A6Z6	nikR	PTHR34719:SF2	NICKEL-RESPONSIVE REGULATOR	NICKEL-RESPONSIVE REGULATOR	DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676	regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468			
ECOLI|EnsemblGenome=b1590|UniProtKB=P76173	P76173	ynfH	PTHR38095:SF1	ANAEROBIC DIMETHYL SULFOXIDE REDUCTASE CHAIN YNFH	ANAEROBIC DIMETHYL SULFOXIDE REDUCTASE CHAIN YNFH	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824	anaerobic respiration#GO:0009061;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;metabolic process#GO:0008152	cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	reductase#PC00198	
ECOLI|EnsemblGenome=b3169|UniProtKB=P0AFF6	P0AFF6	nusA	PTHR22648:SF0	TRANSCRIPTION TERMINATION FACTOR NUSA	TRANSCRIPTION TERMINATION_ANTITERMINATION PROTEIN NUSA		negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular component organization#GO:0051128;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of DNA-templated transcription#GO:0006355;negative regulation of cellular component organization#GO:0051129;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b2038|UniProtKB=P37745	P37745	rfbC	PTHR21047:SF2	DTDP-6-DEOXY-D-GLUCOSE-3,5 EPIMERASE	DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE	catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853	nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;polysaccharide biosynthetic process#GO:0000271;nucleotide-sugar metabolic process#GO:0009225;carbohydrate biosynthetic process#GO:0016051;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	epimerase/racemase#PC00096	O-antigen biosynthesis#P02757>dTDP-4-dehydrorhamnose 3,5-epimerase#P03047
ECOLI|EnsemblGenome=b2662|UniProtKB=P22256	P22256	gabT	PTHR43206:SF5	AMINOTRANSFERASE	4-AMINOBUTYRATE AMINOTRANSFERASE GABT	heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094	oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262	Aminobutyrate degradation#P02726>4-aminobutyrate aminotransferase#P02825
ECOLI|EnsemblGenome=b0924|UniProtKB=P22523	P22523	mukB	PTHR42963:SF1	CHROMOSOME PARTITION PROTEIN MUKB	DUF4476 DOMAIN-CONTAINING PROTEIN			intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	chromatin/chromatin-binding, or -regulatory protein#PC00077	
ECOLI|EnsemblGenome=b4197|UniProtKB=P39305	P39305	ulaE	PTHR43489:SF8	ISOMERASE	L-RIBULOSE-5-PHOSPHATE 3-EPIMERASE ULAE	isomerase activity#GO:0016853;racemase and epimerase activity#GO:0016854;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;catalytic activity#GO:0003824	primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;L-ascorbic acid metabolic process#GO:0019852;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;monosaccharide metabolic process#GO:0005996		isomerase#PC00135;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1428|UniProtKB=P76100	P76100	ydcK	PTHR43584:SF2	NUCLEOTIDYL TRANSFERASE	NUCLEOSIDE-DIPHOSPHATE-SUGAR PYROPHOSPHORYLASES	nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;N-acetyltransferase activity#GO:0008080	cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleotide-sugar metabolic process#GO:0009225;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;amino sugar metabolic process#GO:0006040;small molecule metabolic process#GO:0044281;UDP-N-acetylglucosamine biosynthetic process#GO:0006048;organophosphate biosynthetic process#GO:0090407;UDP-N-acetylglucosamine metabolic process#GO:0006047	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	nucleotidyltransferase#PC00174;transferase#PC00220	
ECOLI|EnsemblGenome=b3660|UniProtKB=P31437	P31437	yicL	PTHR22911:SF143	ACYL-MALONYL CONDENSING ENZYME-RELATED	SUBFAMILY NOT NAMED			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b4003|UniProtKB=P14377	P14377	zraS	PTHR43065:SF54	SENSOR HISTIDINE KINASE	SENSOR HISTIDINE KINASE ZRAS-RELATED			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	histidine kinase receptor of two-component system#PC00265	
ECOLI|EnsemblGenome=b1037|UniProtKB=P0AEA2	P0AEA2	csgG	PTHR41164:SF1	CURLI PRODUCTION ASSEMBLY/TRANSPORT COMPONENT CSGG	CURLI PRODUCTION ASSEMBLY_TRANSPORT COMPONENT CSGG					
ECOLI|EnsemblGenome=b0170|UniProtKB=P0A6P1	P0A6P1	tsf	PTHR11741:SF11	ELONGATION FACTOR TS	ELONGATION FACTOR TS	translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051	metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058		translation elongation factor#PC00222	
ECOLI|EnsemblGenome=b1311|UniProtKB=P0AFR7	P0AFR7	ycjO	PTHR30193:SF37	ABC TRANSPORTER PERMEASE PROTEIN	MALTOSE TRANSPORT SYSTEM PERMEASE PROTEIN YCJO				ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b2173|UniProtKB=P33030	P33030	yeiR	PTHR13748:SF31	COBW-RELATED	ZINC-REGULATED GTPASE METALLOPROTEIN ACTIVATOR 1A-RELATED	zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;molecular carrier activity#GO:0140104;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872	protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2054|UniProtKB=P0ACD2	P0ACD2	wcaF	PTHR23416:SF23	SIALIC ACID SYNTHASE-RELATED	ACETYLTRANSFERASE C18B11.09C-RELATED	acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824			transferase#PC00220;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b4211|UniProtKB=P39315	P39315	qorB	PTHR47129:SF2	QUINONE OXIDOREDUCTASE 2	QUINONE OXIDOREDUCTASE 2	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;catalytic activity#GO:0003824		cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0849|UniProtKB=P68688	P68688	grxA	PTHR45694:SF28	GLUTAREDOXIN 2	GLUTAREDOXIN 1	catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036	cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0113|UniProtKB=P0ACL9	P0ACL9	pdhR	PTHR43537:SF34	TRANSCRIPTIONAL REGULATOR, GNTR FAMILY	PYRUVATE DEHYDROGENASE COMPLEX REPRESSOR	transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468		helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b4146|UniProtKB=P39280	P39280	epmB	PTHR30538:SF1	LYSINE 2,3-AMINOMUTASE-RELATED	L-LYSINE 2,3-AMINOMUTASE	binding#GO:0005488;small molecule binding#GO:0036094;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853;iron-sulfur cluster binding#GO:0051536			isomerase#PC00135;mutase#PC00160	
ECOLI|EnsemblGenome=b0947|UniProtKB=P75863	P75863	ycbX	PTHR14237:SF19	MOLYBDOPTERIN COFACTOR SULFURASE  MOSC	FI02892P					
ECOLI|EnsemblGenome=b4384|UniProtKB=P0ABP8	P0ABP8	deoD	PTHR43691:SF2	URIDINE PHOSPHORYLASE	PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE	glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740	primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656;purine-containing compound metabolic process#GO:0072521;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;purine nucleoside metabolic process#GO:0042278;nucleoside catabolic process#GO:0009164;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172	
ECOLI|EnsemblGenome=b0599|UniProtKB=P45579	P45579	hcxA	PTHR43616:SF3	GLYCEROL DEHYDROGENASE	HYDROXYCARBOXYLATE DEHYDROGENASE A	oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824			dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2979|UniProtKB=P0AEP9	P0AEP9	glcD	PTHR42934:SF1	GLYCOLATE OXIDASE SUBUNIT GLCD	GLYCOLATE OXIDASE SUBUNIT GLCD	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824	alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;monocarboxylic acid catabolic process#GO:0072329;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281		dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3172|UniProtKB=P0A6E4	P0A6E4	argG	PTHR11587:SF2	ARGININOSUCCINATE SYNTHASE	ARGININOSUCCINATE SYNTHASE	ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824	small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;L-arginine biosynthetic process#GO:0006526;proteinogenic amino acid biosynthetic process#GO:0170038;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;ligase#PC00142	Arginine biosynthesis#P02728>Argininosuccinate synthase#P02840
ECOLI|EnsemblGenome=b2993|UniProtKB=P37182	P37182	hybD	PTHR30302:SF1	HYDROGENASE 1 MATURATION PROTEASE	HYDROGENASE 2 MATURATION PROTEASE	catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787	biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152		aspartic protease#PC00053;protease#PC00190	
ECOLI|EnsemblGenome=b2527|UniProtKB=P0A6L9	P0A6L9	hscB	PTHR14021:SF15	IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB	CO-CHAPERONE PROTEIN HSCB	ATPase activator activity#GO:0001671;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772		protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494	chaperone#PC00072	
ECOLI|EnsemblGenome=b2451|UniProtKB=P76551	P76551	eutA	PTHR32432:SF13	CELL DIVISION PROTEIN FTSA-RELATED	ETHANOLAMINE AMMONIA-LYASE REACTIVASE EUTA					
ECOLI|EnsemblGenome=b0187|UniProtKB=P52096	P52096	yaeR	PTHR21366:SF31	GLYOXALASE FAMILY PROTEIN	METALLOTHIOL TRANSFERASE FOSB					
ECOLI|EnsemblGenome=b4357|UniProtKB=P39399	P39399	lgoR	PTHR43537:SF51	TRANSCRIPTIONAL REGULATOR, GNTR FAMILY	HTH-TYPE TRANSCRIPTIONAL REGULATOR LGOR-RELATED	double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789		helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b4260|UniProtKB=P68767	P68767	pepA	PTHR11963:SF51	LEUCINE AMINOPEPTIDASE-RELATED	CYTOSOL AMINOPEPTIDASE	aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233	macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	metalloprotease#PC00153;protease#PC00190	
ECOLI|EnsemblGenome=b4328|UniProtKB=P39377	P39377	iadA	PTHR11647:SF98	HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER	ISOASPARTYL DIPEPTIDASE				hydrolase#PC00121	
ECOLI|EnsemblGenome=b3227|UniProtKB=P45428	P45428	dcuD	PTHR42002:SF2	ANAEROBIC C4-DICARBOXYLATE TRANSPORTER DCUC-RELATED	ANAEROBIC C4-DICARBOXYLATE TRANSPORTER DCUC-RELATED	C4-dicarboxylate transmembrane transporter activity#GO:0015556;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;dicarboxylic acid transmembrane transporter activity#GO:0005310	dicarboxylic acid transport#GO:0006835;establishment of localization#GO:0051234;localization#GO:0051179;organic acid transport#GO:0015849;C4-dicarboxylate transport#GO:0015740;transport#GO:0006810;carboxylic acid transport#GO:0046942	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b0533|UniProtKB=P75715	P75715	sfmH	PTHR33420:SF31	FIMBRIAL SUBUNIT ELFA-RELATED	PROTEIN LPFD		cellular process#GO:0009987;cell adhesion#GO:0007155;single-species biofilm formation#GO:0044010;cell-substrate adhesion#GO:0031589	cell projection#GO:0042995;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1193|UniProtKB=P0C960	P0C960	emtA	PTHR37423:SF4	SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE-RELATED	ENDO-TYPE MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE A	carbon-oxygen lyase activity, acting on polysaccharides#GO:0016837;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824;peptidoglycan lytic transglycosylase activity#GO:0008933;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835	cellular process#GO:0009987;cell division#GO:0051301	cellular anatomical structure#GO:0110165;extracellular region#GO:0005576		
ECOLI|EnsemblGenome=b0271|UniProtKB=P77713	P77713	yagH	PTHR42812:SF12	BETA-XYLOSIDASE	BETA-XYLOSIDASE-RELATED				hydrolase#PC00121;glycosidase#PC00110	
ECOLI|EnsemblGenome=b1845|UniProtKB=P24555	P24555	ptrB	PTHR11757:SF22	PROTEASE FAMILY S9A OLIGOPEPTIDASE	PROLYL ENDOPEPTIDASE				serine protease#PC00203	Vasopressin synthesis#P04395>Endo Peptidase#P04596
ECOLI|EnsemblGenome=b0718|UniProtKB=P75750	P75750	ybgQ	PTHR30451:SF4	OUTER MEMBRANE USHER PROTEIN	OUTER MEMBRANE USHER PROTEIN YQIG-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829	cell adhesion#GO:0007155;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;cell outer membrane#GO:0009279;membrane#GO:0016020;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;outer membrane#GO:0019867		
ECOLI|EnsemblGenome=b3236|UniProtKB=P61889	P61889	mdh	PTHR11540:SF16	MALATE AND LACTATE DEHYDROGENASE	MALATE DEHYDROGENASE, CHLOROPLASTIC	oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824		intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	dehydrogenase#PC00092	Pyruvate metabolism#P02772>Lactate Dehydrogenase#P03139
ECOLI|EnsemblGenome=b3827|UniProtKB=P0ADP5	P0ADP5	bioP	PTHR22911:SF130	ACYL-MALONYL CONDENSING ENZYME-RELATED	BIOTIN TRANSPORTER			cellular anatomical structure#GO:0110165;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b0178|UniProtKB=P0AEU7	P0AEU7	skp	PTHR35089:SF1	CHAPERONE PROTEIN SKP	CHAPERONE PROTEIN SKP		protein stabilization#GO:0050821;regulation of biological quality#GO:0065008;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biological regulation#GO:0065007;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;regulation of protein stability#GO:0031647;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238		chaperone#PC00072	
ECOLI|EnsemblGenome=b0568|UniProtKB=P31600	P31600	nfrA	PTHR44858:SF21	TETRATRICOPEPTIDE REPEAT PROTEIN 6	BACTERIOPHAGE ADSORPTION PROTEIN A		biological process involved in interspecies interaction between organisms#GO:0044419;biological process involved in interaction with host#GO:0051701;biological process involved in symbiotic interaction#GO:0044403	cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;outer membrane#GO:0019867;external encapsulating structure#GO:0030312;cell outer membrane#GO:0009279;membrane#GO:0016020		
ECOLI|EnsemblGenome=b4118|UniProtKB=P0ACH8	P0ACH8	melR	PTHR43280:SF14	ARAC-FAMILY TRANSCRIPTIONAL REGULATOR	MELIBIOSE OPERON REGULATORY PROTEIN	sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488	regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252		DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b3963|UniProtKB=P0ACU5	P0ACU5	fabR	PTHR47752:SF1	HTH-TYPE TRANSCRIPTIONAL REPRESSOR FABR	HTH-TYPE TRANSCRIPTIONAL REPRESSOR FABR				helix-turn-helix transcription factor#PC00116;Tet repressor-like transcription factor#PC00266;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b2086|UniProtKB=P76407	P76407	yegS	PTHR12358:SF106	SPHINGOSINE KINASE	LIPID KINASE YEGS	catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727			metabolite interconversion enzyme#PC00262;kinase#PC00137;transferase#PC00220	
ECOLI|EnsemblGenome=b1853|UniProtKB=P46118	P46118	hexR	PTHR30514:SF1	GLUCOKINASE	HTH-TYPE TRANSCRIPTIONAL REGULATOR HEXR-RELATED	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255	protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991	kinase#PC00137	
ECOLI|EnsemblGenome=b0509|UniProtKB=P77161	P77161	glxR	PTHR43060:SF18	3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED	2-HYDROXY-3-OXOPROPIONATE REDUCTASE	catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614	carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;glyoxylate metabolic process#GO:0046487;monocarboxylic acid catabolic process#GO:0072329;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;aldehyde catabolic process#GO:0046185;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152		dehydrogenase#PC00092;oxidoreductase#PC00176	Allantoin degradation#P02725>Tartronate semi-aldehyde dehydrogenase#P02823
ECOLI|EnsemblGenome=b0143|UniProtKB=P0ABF1	P0ABF1	pcnB	PTHR43051:SF13	POLYNUCLEOTIDE ADENYLYLTRANSFERASE FAMILY PROTEIN	POLY(A) POLYMERASE I			cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	mRNA polyadenylation factor#PC00146	
ECOLI|EnsemblGenome=b2498|UniProtKB=P0A8F0	P0A8F0	upp	PTHR10285:SF237	URIDINE KINASE	URACIL PHOSPHORIBOSYLTRANSFERASE	glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	nucleotide kinase#PC00172;kinase#PC00137	Salvage pyrimidine ribonucleotides#P02775>Uracil phosphoribosyl  transferase#P03151
ECOLI|EnsemblGenome=b3252|UniProtKB=P13518	P13518	csrD	PTHR33121:SF32	CYCLIC DI-GMP PHOSPHODIESTERASE PDEF	RNASE E SPECIFICITY FACTOR CSRD	hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121	
ECOLI|EnsemblGenome=b2329|UniProtKB=P12008	P12008	aroC	PTHR21085:SF0	CHORISMATE SYNTHASE	CHORISMATE SYNTHASE, CHLOROPLASTIC	catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829	small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;aromatic amino acid biosynthetic process#GO:0009073	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	lyase#PC00144	Chorismate biosynthesis#P02734>Chorismate synthase#P02868
ECOLI|EnsemblGenome=b2879|UniProtKB=Q46812	Q46812	ssnA	PTHR43794:SF11	AMINOHYDROLASE SSNA-RELATED	AMIDOHYDROLASE-RELATED DOMAIN-CONTAINING PROTEIN	catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;deaminase activity#GO:0019239			hydrolase#PC00121;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b4290|UniProtKB=P15028	P15028	fecB	PTHR30532:SF29	IRON III  DICITRATE-BINDING PERIPLASMIC PROTEIN	FE(3+) DICITRATE-BINDING PERIPLASMIC PROTEIN FECB		siderophore-iron import into cell#GO:0033214;monoatomic ion homeostasis#GO:0050801;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;iron coordination entity transport#GO:1901678;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular iron ion homeostasis#GO:0006879;metal ion transport#GO:0030001;homeostatic process#GO:0042592;iron import into cell#GO:0033212;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic cation transport#GO:0006812;localization#GO:0051179;siderophore-dependent iron import pathway#GO:0180060;cellular localization#GO:0051641;monoatomic ion transport#GO:0006811;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771	periplasmic space#GO:0042597;extracellular region#GO:0005576;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313		
ECOLI|EnsemblGenome=b0517|UniProtKB=P77555	P77555	allD	PTHR11091:SF0	OXIDOREDUCTASE-RELATED	MALATE DEHYDROGENASE				oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	Allantoin degradation#P02725>Ureidoglycolate dehydrogenase#P02820;TCA cycle#P00051>Malate Dehydrogenase#P01270;Pyruvate metabolism#P02772>Malate Dehydrogenase#P03138
ECOLI|EnsemblGenome=b2080|UniProtKB=P76402	P76402	yegP	PTHR40606:SF1	FAMILY NOT NAMED	UPF0339 PROTEIN YEGP					
ECOLI|EnsemblGenome=b4015|UniProtKB=P0A9G6	P0A9G6	aceA	PTHR21631:SF3	ISOCITRATE LYASE/MALATE SYNTHASE	ISOCITRATE LYASE	catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829	oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carbohydrate metabolic process#GO:0005975;glyoxylate metabolic process#GO:0046487;small molecule metabolic process#GO:0044281		lyase#PC00144;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1083|UniProtKB=P29744	P29744	flgL	PTHR42792:SF1	FLAGELLIN	FLAGELLAR HOOK-ASSOCIATED PROTEIN 3		cell motility#GO:0048870;bacterial-type flagellum-dependent cell motility#GO:0071973;cellular process#GO:0009987;cilium or flagellum-dependent cell motility#GO:0001539;archaeal or bacterial-type flagellum-dependent cell motility#GO:0097588		structural protein#PC00211	
ECOLI|EnsemblGenome=b3081|UniProtKB=P42593	P42593	fadH	PTHR42917:SF3	2,4-DIENOYL-COA REDUCTASE	2,4-DIENOYL-COA REDUCTASE [(2E)-ENOYL-COA-PRODUCING]	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824			metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3302|UniProtKB=P0AG51	P0AG51	rpmD	PTHR15892:SF4	MITOCHONDRIAL RIBOSOMAL PROTEIN L30	LARGE RIBOSOMAL SUBUNIT PROTEIN UL30	structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735	translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467		ribosomal protein#PC00202;translational protein#PC00263	
ECOLI|EnsemblGenome=b2059|UniProtKB=P77414	P77414	wcaA	PTHR22916:SF77	GLYCOSYLTRANSFERASE	COLANIC ACID BIOSYNTHESIS GLYCOSYL TRANSFERASE WCAA-RELATED	catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757	lipopolysaccharide core region biosynthetic process#GO:0009244;lipopolysaccharide biosynthetic process#GO:0009103;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;liposaccharide metabolic process#GO:1903509;primary metabolic process#GO:0044238;oligosaccharide biosynthetic process#GO:0009312;lipopolysaccharide metabolic process#GO:0008653;polysaccharide biosynthetic process#GO:0000271;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;oligosaccharide metabolic process#GO:0009311;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;lipid metabolic process#GO:0006629;metabolic process#GO:0008152		glycosyltransferase#PC00111;transferase#PC00220	
ECOLI|EnsemblGenome=b1308|UniProtKB=P23857	P23857	pspE	PTHR44086:SF16	THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED	THIOSULFATE SULFURTRANSFERASE PSPE-RELATED	transferase activity#GO:0016740;catalytic activity#GO:0003824;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782			transferase#PC00220	
ECOLI|EnsemblGenome=b0781|UniProtKB=P30745	P30745	moaA	PTHR22960:SF28	MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A	GTP 3',8-CYCLASE	carbon-carbon lyase activity#GO:0016830;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;lyase activity#GO:0016829	metabolic process#GO:0008152;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;biosynthetic process#GO:0009058			
ECOLI|EnsemblGenome=b3823|UniProtKB=P0AG38	P0AG38	rhtC	PTHR30086:SF19	ARGININE EXPORTER PROTEIN ARGO	THREONINE EFFLUX PROTEIN	amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	amino acid transport#GO:0006865;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1385|UniProtKB=P80668	P80668	feaB	PTHR11699:SF307	ALDEHYDE DEHYDROGENASE-RELATED	PHENYLACETALDEHYDE DEHYDROGENASE	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491	catabolic process#GO:0009056;amine metabolic process#GO:0009308;metabolic process#GO:0008152;cellular process#GO:0009987;amine catabolic process#GO:0009310		metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402;Phenylethylamine degradation#P02766>Phenylacetaldehyde dehydrogenase#P03102
ECOLI|EnsemblGenome=b2685|UniProtKB=P27303	P27303	emrA	PTHR30386:SF19	MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP	MULTIDRUG EXPORT PROTEIN EMRA-RELATED	bile acid transmembrane transporter activity#GO:0015125;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	xenobiotic transport#GO:0042908;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;cellular process#GO:0009987;xenobiotic detoxification by transmembrane export across the plasma membrane#GO:1990961;lipid transport#GO:0006869;response to chemical#GO:0042221;detoxification#GO:0098754;lipid localization#GO:0010876;bile acid and bile salt transport#GO:0015721;localization#GO:0051179;transmembrane transport#GO:0055085;organic hydroxy compound transport#GO:0015850;monocarboxylic acid transport#GO:0015718;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;export from cell#GO:0140352	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b3929|UniProtKB=P0A8R0	P0A8R0	rraA	PTHR33254:SF33	4-HYDROXY-4-METHYL-2-OXOGLUTARATE ALDOLASE 3-RELATED	REGULATOR OF RIBONUCLEASE ACTIVITY A		negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;regulation of catabolic process#GO:0009894	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	aldolase#PC00044;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1098|UniProtKB=P0A720	P0A720	tmk	PTHR10344:SF4	THYMIDYLATE KINASE	THYMIDYLATE KINASE	phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772	carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;nucleoside diphosphate metabolic process#GO:0009132;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	transferase#PC00220;nucleotide kinase#PC00172;kinase#PC00137	De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTMP kinase#P02916
ECOLI|EnsemblGenome=b0504|UniProtKB=P0ACR0	P0ACR0	allS	PTHR30579:SF0	TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL ACTIVATOR ALLS	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007		DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b3924|UniProtKB=P28861	P28861	fpr	PTHR47878:SF1	OXIDOREDUCTASE FAD/NAD(P)-BINDING DOMAIN PROTEIN	FLAVODOXIN_FERREDOXIN--NADP REDUCTASE		catabolic process#GO:0009056;heme metabolic process#GO:0042168;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;pigment metabolic process#GO:0042440;porphyrin-containing compound metabolic process#GO:0006778;cellular process#GO:0009987		oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1609|UniProtKB=P18392	P18392	rstB	PTHR44936:SF10	SENSOR PROTEIN CREC	SENSOR PROTEIN RSTB	phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;phosphorelay sensor kinase activity#GO:0000155;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein histidine kinase activity#GO:0004673;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|Gene_OrderedLocusName=JW1470|UniProtKB=P24183	P24183	fdnG	PTHR43598:SF7	TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE 2 SUBUNIT B	FORMATE DEHYDROGENASE, NITRATE-INDUCIBLE, MAJOR SUBUNIT	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	generation of precursor metabolites and energy#GO:0006091;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;anaerobic respiration#GO:0009061;small molecule metabolic process#GO:0044281	protein-containing complex#GO:0032991;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204	dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b3662|UniProtKB=P0ADL1	P0ADL1	nepI	PTHR43124:SF5	PURINE EFFLUX PUMP PBUE	PURINE RIBONUCLEOSIDE EFFLUX PUMP NEPI	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b3305|UniProtKB=P0AG55	P0AG55	rplF	PTHR11655:SF14	60S/50S RIBOSOMAL PROTEIN L6/L9	LARGE RIBOSOMAL SUBUNIT PROTEIN UL6	structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198	metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058		ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b0114|UniProtKB=P0AFG8	P0AFG8	aceE	PTHR43825:SF3	PYRUVATE DEHYDROGENASE E1 COMPONENT	PYRUVATE DEHYDROGENASE E1 COMPONENT				dehydrogenase#PC00092;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3144|UniProtKB=P42915	P42915	yraJ	PTHR30451:SF21	OUTER MEMBRANE USHER PROTEIN	FIMBRIAL USHER DOMAIN-CONTAINING PROTEIN YDET-RELATED	wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	cellular process#GO:0009987;cell adhesion#GO:0007155	cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;external encapsulating structure#GO:0030312;membrane#GO:0016020;cell outer membrane#GO:0009279;outer membrane#GO:0019867;extracellular region#GO:0005576		
ECOLI|EnsemblGenome=b3926|UniProtKB=P0A6F3	P0A6F3	glpK	PTHR10196:SF100	SUGAR KINASE	GLYCEROL KINASE	kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773	carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	carbohydrate kinase#PC00065;kinase#PC00137	
ECOLI|EnsemblGenome=b2996|UniProtKB=P0AAJ8	P0AAJ8	hybA	PTHR43545:SF1	FORMATE DEHYDROGENASE, NITRATE-INDUCIBLE, IRON-SULFUR SUBUNIT	HYDROGENASE-2 OPERON PROTEIN HYBA	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;anaerobic respiration#GO:0009061;small molecule metabolic process#GO:0044281;generation of precursor metabolites and energy#GO:0006091;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333	oxidoreductase complex#GO:1990204;catalytic complex#GO:1902494;protein-containing complex#GO:0032991	metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3205|UniProtKB=P0A894	P0A894	rapZ	PTHR30448:SF0	RNASE ADAPTER PROTEIN RAPZ	RNASE ADAPTER PROTEIN RAPZ					
ECOLI|EnsemblGenome=b2468|UniProtKB=P37127	P37127	aegA	PTHR42783:SF1	GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN	OXIDOREDUCTASE AEGA-RELATED	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	purine-containing compound catabolic process#GO:0072523;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987		metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3329|UniProtKB=P41443	P41443	gspH	PTHR30093:SF53	GENERAL SECRETION PATHWAY PROTEIN G	TYPE II SECRETION SYSTEM PROTEIN H					
ECOLI|EnsemblGenome=b3821|UniProtKB=P0A921	P0A921	pldA	PTHR40457:SF1	PHOSPHOLIPASE A1	PHOSPHOLIPASE A1	hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;A2-type glycerophospholipase activity#GO:0004623;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;hydrolase activity#GO:0016787	metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylglycerol metabolic process#GO:0046471;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;cell outer membrane#GO:0009279;membrane#GO:0016020;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;outer membrane#GO:0019867	phospholipase#PC00186	
ECOLI|EnsemblGenome=b0325|UniProtKB=P75691	P75691	yahK	PTHR42683:SF65	ALDEHYDE REDUCTASE	ZINC-CONTAINING ALCOHOL DEHYDROGENASE				oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3039|UniProtKB=P24197	P24197	ygiD	PTHR30096:SF0	4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN	4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN					
ECOLI|EnsemblGenome=b3622|UniProtKB=P27243	P27243	waaL	PTHR37422:SF17	TEICHURONIC ACID BIOSYNTHESIS PROTEIN TUAE	O-ANTIGEN LIGASE	glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740	macromolecule metabolic process#GO:0043170;polysaccharide biosynthetic process#GO:0000271;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975;carbohydrate biosynthetic process#GO:0016051;polysaccharide metabolic process#GO:0005976;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b0335|UniProtKB=P77495	P77495	prpE	PTHR43347:SF3	ACYL-COA SYNTHETASE	ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER B, MITOCHONDRIAL				ligase#PC00142;metabolite interconversion enzyme#PC00262	Acetate utilization#P02722>Acetyl-CoA synthetase#P02803;Methylcitrate cycle#P02754>Acetyl-CoA synthetase#P03030
ECOLI|Gene_OrderedLocusName=JW5327|UniProtKB=P76359	P76359	yeeP	PTHR42714:SF2	TRNA MODIFICATION GTPASE GTPBP3	TRNA MODIFICATION GTPASE MNME		RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	RNA metabolism protein#PC00031;RNA methyltransferase#PC00033	
ECOLI|EnsemblGenome=b0963|UniProtKB=P0A731	P0A731	mgsA	PTHR30492:SF0	METHYLGLYOXAL SYNTHASE	METHYLGLYOXAL SYNTHASE	catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835	small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;ketone biosynthetic process#GO:0042181;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0969|UniProtKB=P0AB18	P0AB18	tusE	PTHR37010:SF1	SULFURTRANSFERASE TUSE	SULFURTRANSFERASE TUSE	molecular carrier activity#GO:0140104	tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;tRNA wobble position uridine thiolation#GO:0002143;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;tRNA thio-modification#GO:0034227;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152		transferase#PC00220;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1805|UniProtKB=P69451	P69451	fadD	PTHR43767:SF8	LONG-CHAIN-FATTY-ACID--COA LIGASE	LONG-CHAIN-FATTY-ACID--COA LIGASE	catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874	lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238		metabolite interconversion enzyme#PC00262;ligase#PC00142	
ECOLI|EnsemblGenome=b4317|UniProtKB=P30130	P30130	fimD	PTHR30451:SF21	OUTER MEMBRANE USHER PROTEIN	FIMBRIAL USHER DOMAIN-CONTAINING PROTEIN YDET-RELATED	passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;channel activity#GO:0015267	cell adhesion#GO:0007155;cellular process#GO:0009987	cell outer membrane#GO:0009279;membrane#GO:0016020;external encapsulating structure#GO:0030312;outer membrane#GO:0019867;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313		
ECOLI|EnsemblGenome=b0495|UniProtKB=P0A9T8	P0A9T8	ybbA	PTHR42798:SF2	LIPOPROTEIN-RELEASING SYSTEM ATP-BINDING PROTEIN LOLD	LIPOPROTEIN-RELEASING SYSTEM ATP-BINDING PROTEIN LOLD		establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810		ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b1264|UniProtKB=P00895	P00895	trpE	PTHR11236:SF49	AMINOBENZOATE/ANTHRANILATE SYNTHASE	ANTHRANILATE SYNTHASE COMPONENT 1		small molecule metabolic process#GO:0044281;aromatic amino acid biosynthetic process#GO:0009073;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;indole-containing compound metabolic process#GO:0042430;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;amine metabolic process#GO:0009308;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283			
ECOLI|EnsemblGenome=b3547|UniProtKB=P37662	P37662	yhjX	PTHR11360:SF317	MONOCARBOXYLATE TRANSPORTER	MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b2324|UniProtKB=P77182	P77182	mnmC	PTHR13847:SF283	SARCOSINE DEHYDROGENASE-RELATED	TRNA 5-METHYLAMINOMETHYL-2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC	RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168	RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b3748|UniProtKB=P04982	P04982	rbsD	PTHR37831:SF1	D-RIBOSE PYRANASE	D-RIBOSE PYRANASE	intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;isomerase activity#GO:0016853	carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b0593|UniProtKB=P0AEJ2	P0AEJ2	entC	PTHR42839:SF2	ISOCHORISMATE SYNTHASE ENTC	ISOCHORISMATE SYNTHASE ENTC	isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824				
ECOLI|EnsemblGenome=b0537|UniProtKB=P24218	P24218	intD	PTHR30349:SF99	PHAGE INTEGRASE-RELATED	PROPHAGE INTEGRASE INTD-RELATED	catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640	nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;chromosome segregation#GO:0007059;DNA recombination#GO:0006310		viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b0443|UniProtKB=P77712	P77712	fadM	PTHR31793:SF24	4-HYDROXYBENZOYL-COA THIOESTERASE FAMILY MEMBER	LONG-CHAIN ACYL-COA THIOESTERASE FADM				metabolite interconversion enzyme#PC00262;esterase#PC00097;hydrolase#PC00121	
ECOLI|EnsemblGenome=b1616|UniProtKB=P0CE44	P0CE44	uidB	PTHR11328:SF39	MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN	2,3-DIHYDROXYPROPANE-1-SULFONATE EXPORTER-RELATED		transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	primary active transporter#PC00068	
ECOLI|EnsemblGenome=b1485|UniProtKB=P77463	P77463	ddpC	PTHR43386:SF28	OLIGOPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN APPC	D,D-DIPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN DDPC-RELATED	oligopeptide transmembrane transporter activity#GO:0035673;dipeptide transmembrane transporter activity#GO:0071916;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b0944|UniProtKB=P40876	P40876	ycbF	PTHR30251:SF1	PILUS ASSEMBLY CHAPERONE	FIMBRIAL CHAPARONE		metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467	periplasmic space#GO:0042597;extracellular region#GO:0005576;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313	chaperone#PC00072	
ECOLI|EnsemblGenome=b1808|UniProtKB=P76257	P76257	yoaA	PTHR11472:SF65	DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER	ATP-DEPENDENT DNA HELICASE YOAA	helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657			DNA metabolism protein#PC00009;DNA helicase#PC00011	
ECOLI|EnsemblGenome=b3654|UniProtKB=P0AGM9	P0AGM9	xanP	PTHR42810:SF2	PURINE PERMEASE C1399.01C-RELATED	XANTHINE PERMEASE XANP	nucleobase transmembrane transporter activity#GO:0015205;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	establishment of localization#GO:0051234;localization#GO:0051179;nitrogen compound transport#GO:0071705;nucleobase transport#GO:0015851;transport#GO:0006810	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b1498|UniProtKB=P77318	P77318	ydeN	PTHR42693:SF53	ARYLSULFATASE FAMILY MEMBER	SULFATASE ASLA-RELATED	hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788			hydrolase#PC00121	
ECOLI|EnsemblGenome=b0058|UniProtKB=P0AA37	P0AA37	rluA	PTHR21600:SF91	MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE	DUAL-SPECIFICITY RNA PSEUDOURIDINE SYNTHASE RLUA	isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866	RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA modification#GO:0000154;pseudouridine synthesis#GO:0001522;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059		RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b2880|UniProtKB=P64557	P64557	ygfM	PTHR42659:SF2	XANTHINE DEHYDROGENASE SUBUNIT C-RELATED	XANTHINE DEHYDROGENASE SUBUNIT C-RELATED	oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0131|UniProtKB=P0A790	P0A790	panD	PTHR21012:SF0	ASPARTATE 1-DECARBOXYLASE	ASPARTATE 1-DECARBOXYLASE	carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;lyase activity#GO:0016829	monocarboxylic acid metabolic process#GO:0032787;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	decarboxylase#PC00089	Pantothenate biosynthesis#P02761>Aspartate decarboxylase#P03066
ECOLI|EnsemblGenome=b0826|UniProtKB=P12282	P12282	moeB	PTHR10953:SF255	UBIQUITIN-ACTIVATING ENZYME E1	MOLYBDOPTERIN-SYNTHASE ADENYLYLTRANSFERASE	sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234	
ECOLI|EnsemblGenome=b2802|UniProtKB=P69922	P69922	fucI	PTHR37840:SF1	L-FUCOSE ISOMERASE	L-FUCOSE ISOMERASE	intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860	monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052;cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056		metabolite interconversion enzyme#PC00262;isomerase#PC00135	
ECOLI|EnsemblGenome=b3501|UniProtKB=P37309	P37309	arsR	PTHR33154:SF18	TRANSCRIPTIONAL REGULATOR, ARSR FAMILY	ARSENICAL RESISTANCE OPERON REPRESSOR		regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794		winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b2833|UniProtKB=P65294	P65294	ygdR	PTHR37011:SF1	POT FAMILY PEPTIDE TRANSPORT PROTEIN-RELATED	LIPOPROTEIN YGDI_YGDR-LIKE SH3-LIKE DOMAIN-CONTAINING PROTEIN					
ECOLI|EnsemblGenome=b1073|UniProtKB=P0ABW9	P0ABW9	flgB	PTHR30435:SF12	FLAGELLAR PROTEIN	FLAGELLAR BASAL BODY ROD PROTEIN FLGB		bacterial-type flagellum-dependent swarming motility#GO:0071978;archaeal or bacterial-type flagellum-dependent cell motility#GO:0097588;cellular process#GO:0009987;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;bacterial-type flagellum-dependent cell motility#GO:0071973	bacterial-type flagellum#GO:0009288;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;cell projection#GO:0042995	structural protein#PC00211	
ECOLI|EnsemblGenome=b2737|UniProtKB=Q46889	Q46889	otnK	PTHR30304:SF3	D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE	3-OXO-TETRONATE KINASE				lyase#PC00144;aldolase#PC00044	
ECOLI|EnsemblGenome=b2502|UniProtKB=P0AFL6	P0AFL6	ppx	PTHR30005:SF14	EXOPOLYPHOSPHATASE	EXOPOLYPHOSPHATASE	hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462	catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;phosphorus metabolic process#GO:0006793		metabolite interconversion enzyme#PC00262;phosphatase#PC00181	
ECOLI|EnsemblGenome=b2223|UniProtKB=P76460	P76460	atoE	PTHR41983:SF2	SHORT-CHAIN FATTY ACID TRANSPORTER-RELATED	SHORT-CHAIN FATTY ACID TRANSPORTER-RELATED			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b3735|UniProtKB=P0ABA4	P0ABA4	atpH	PTHR11910:SF22	ATP SYNTHASE DELTA CHAIN	ATP SYNTHASE SUBUNIT DELTA	monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;channel activity#GO:0015267;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;proton channel activity#GO:0015252;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874	organophosphate biosynthetic process#GO:0090407;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;ATP biosynthetic process#GO:0006754;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390		primary active transporter#PC00068;transporter#PC00227;ATP synthase#PC00002	
ECOLI|EnsemblGenome=b3164|UniProtKB=P05055	P05055	pnp	PTHR11252:SF17	POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE	POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE	hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787	nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA catabolic process#GO:0006401;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	nucleotidyltransferase#PC00174	
ECOLI|EnsemblGenome=b3337|UniProtKB=P0AE56	P0AE56	bfd	PTHR37424:SF1	BACTERIOFERRITIN-ASSOCIATED FERREDOXIN	BACTERIOFERRITIN-ASSOCIATED FERREDOXIN	small molecule binding#GO:0036094;binding#GO:0005488;iron-sulfur cluster binding#GO:0051536			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2199|UniProtKB=P0ABM1	P0ABM1	ccmC	PTHR30071:SF1	HEME EXPORTER PROTEIN C	HEME EXPORTER PROTEIN C	oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824	protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b3885|UniProtKB=P0A8Y3	P0A8Y3	yihX	PTHR43611:SF4	ALPHA-D-GLUCOSE 1-PHOSPHATE PHOSPHATASE	ALPHA-D-GLUCOSE 1-PHOSPHATE PHOSPHATASE YIHX	hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;sugar-phosphatase activity#GO:0050308;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787			metabolite interconversion enzyme#PC00262;phosphatase#PC00181	
ECOLI|EnsemblGenome=b0728|UniProtKB=P0A836	P0A836	sucC	PTHR11815:SF17	SUCCINYL-COA SYNTHETASE BETA CHAIN	SUCCINATE--COA LIGASE [ADP-FORMING] SUBUNIT BETA	ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824	cellular respiration#GO:0045333;aerobic respiration#GO:0009060;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;energy derivation by oxidation of organic compounds#GO:0015980;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;sulfur compound metabolic process#GO:0006790;tricarboxylic acid cycle#GO:0006099;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829;catalytic complex#GO:1902494	ligase#PC00142	
ECOLI|EnsemblGenome=b0339|UniProtKB=P0ABE9	P0ABE9	cynT	PTHR11002:SF42	CARBONIC ANHYDRASE	CARBONIC ANHYDRASE 1				lyase#PC00144;dehydratase#PC00091	
ECOLI|EnsemblGenome=b2020|UniProtKB=P06988	P06988	hisD	PTHR21256:SF15	HISTIDINOL DEHYDROGENASE  HDH	HISTIDINOL DEHYDROGENASE	catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614	amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;aromatic amino acid biosynthetic process#GO:0009073;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	Histidine biosynthesis#P02747>Histidinol dehydrogenase#P02985;Histidine biosynthesis#P02747>Histidinal dehydrogenase#P02988
ECOLI|EnsemblGenome=b1912|UniProtKB=P0ABF8	P0ABF8	pgsA	PTHR14269:SF66	CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED	CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE		metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	metabolite interconversion enzyme#PC00262;transferase#PC00220	
ECOLI|EnsemblGenome=b4069|UniProtKB=P27550	P27550	acs	PTHR24095:SF243	ACETYL-COENZYME A SYNTHETASE	ACETYL-COENZYME A SYNTHETASE	ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877	phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound biosynthetic process#GO:0072522;acetyl-CoA metabolic process#GO:0006084;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	ligase#PC00142	Acetate utilization#P02722>Acetyl-CoA synthetase#P02803
ECOLI|EnsemblGenome=b0088|UniProtKB=P14900	P14900	murD	PTHR43692:SF1	UDP-N-ACETYLMURAMOYLALANINE--D-GLUTAMATE LIGASE	UDP-N-ACETYLMURAMOYLALANINE--D-GLUTAMATE LIGASE	catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879	glycosaminoglycan metabolic process#GO:0030203;aminoglycan biosynthetic process#GO:0006023;peptidoglycan biosynthetic process#GO:0009252;aminoglycan metabolic process#GO:0006022;cell wall macromolecule metabolic process#GO:0044036;cell wall biogenesis#GO:0042546;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell wall macromolecule biosynthetic process#GO:0044038;biosynthetic process#GO:0009058;cell wall organization or biogenesis#GO:0071554;peptidoglycan metabolic process#GO:0000270;metabolic process#GO:0008152;peptidoglycan-based cell wall biogenesis#GO:0009273;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;glycosaminoglycan biosynthetic process#GO:0006024;carbohydrate derivative biosynthetic process#GO:1901137		ligase#PC00142	Peptidoglycan biosynthesis#P02763>UDP-N-acetylmuramoylalanine-D-glutamate ligase#P03083
ECOLI|EnsemblGenome=b0920|UniProtKB=P0AB01	P0AB01	elyC	PTHR30336:SF4	INNER MEMBRANE PROTEIN, PROBABLE PERMEASE	ENVELOPE BIOGENESIS FACTOR ELYC		cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycosaminoglycan metabolic process#GO:0030203;cellular component biogenesis#GO:0044085;cell wall organization or biogenesis#GO:0071554;peptidoglycan-based cell wall biogenesis#GO:0009273;peptidoglycan metabolic process#GO:0000270;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;cell wall biogenesis#GO:0042546;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b3865|UniProtKB=P0A6P7	P0A6P7	engB	PTHR11649:SF80	MSS1/TRME-RELATED GTP-BINDING PROTEIN	GTP-BINDING PROTEIN ENGB-RELATED			cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	G-protein#PC00020	
ECOLI|EnsemblGenome=b3403|UniProtKB=P22259	P22259	pckA	PTHR30031:SF31	PHOSPHOENOLPYRUVATE CARBOXYKINASE  ATP	PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP)	lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831	small molecule biosynthetic process#GO:0044283;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;glucose metabolic process#GO:0006006;cellular process#GO:0009987;hexose biosynthetic process#GO:0019319;gluconeogenesis#GO:0006094;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate biosynthetic process#GO:0016051;carbohydrate metabolic process#GO:0005975;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	kinase#PC00137	
ECOLI|EnsemblGenome=b2869|UniProtKB=Q46802	Q46802	uacR	PTHR32071:SF117	TRANSCRIPTIONAL REGULATORY PROTEIN	PTS-DEPENDENT DIHYDROXYACETONE KINASE OPERON REGULATORY PROTEIN-RELATED	DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556	protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991	DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b2211|UniProtKB=P33941	P33941	yojI	PTHR43553:SF11	HEAVY METAL TRANSPORTER	ABC TRANSPORTER ATP-BINDING_PERMEASE PROTEIN YOJI	nucleotide binding#GO:0000166;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transmembrane transporter activity#GO:0022857;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;binding#GO:0005488;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657		transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;ATP-binding cassette (ABC) transporter complex#GO:0043190;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886	primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b2878|UniProtKB=Q46811	Q46811	ygfK	PTHR11938:SF91	FAD NADPH DEHYDROGENASE/OXIDOREDUCTASE	NADPH:ADRENODOXIN OXIDOREDUCTASE, MITOCHONDRIAL	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824			oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	Vitamin D metabolism and pathway#P04396>FdxR#P04604
ECOLI|EnsemblGenome=b1764|UniProtKB=P16456	P16456	selD	PTHR10256:SF0	SELENIDE, WATER DIKINASE	INACTIVE SELENIDE, WATER DIKINASE-LIKE PROTEIN-RELATED	transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824	carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	metabolite interconversion enzyme#PC00262;transferase#PC00220	
ECOLI|EnsemblGenome=b1660|UniProtKB=P37597	P37597	punC	PTHR23502:SF162	MAJOR FACILITATOR SUPERFAMILY	PURINE NUCLEOSIDE TRANSPORTER	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;xenobiotic transport#GO:0042908;transport#GO:0006810;response to toxic substance#GO:0009636;response to chemical#GO:0042221;response to stimulus#GO:0050896;detoxification#GO:0098754;export from cell#GO:0140352;cellular process#GO:0009987;xenobiotic detoxification by transmembrane export across the plasma membrane#GO:1990961	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b4191|UniProtKB=P0A9W0	P0A9W0	ulaR	PTHR30363:SF55	HTH-TYPE TRANSCRIPTIONAL REGULATOR SRLR-RELATED	HTH-TYPE TRANSCRIPTIONAL REGULATOR ULAR	sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007		helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b3911|UniProtKB=P0AE82	P0AE82	cpxA	PTHR45528:SF14	SENSOR HISTIDINE KINASE CPXA	SENSOR HISTIDINE KINASE CPXA	phosphorelay sensor kinase activity#GO:0000155;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein histidine kinase activity#GO:0004673;catalytic activity, acting on a protein#GO:0140096;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	histidine kinase receptor of two-component system#PC00265;transmembrane signal receptor#PC00197	
ECOLI|EnsemblGenome=b1411|UniProtKB=P76093	P76093	ynbD	PTHR47216:SF5	FAMILY NOT NAMED	TYROSINE SPECIFIC PROTEIN PHOSPHATASES DOMAIN-CONTAINING PROTEIN			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b0039|UniProtKB=P60584	P60584	caiA	PTHR48083:SF23	MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED	CROTONOBETAINYL-COA REDUCTASE	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627	small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b2724|UniProtKB=P0AAK1	P0AAK1	hycB	PTHR42859:SF16	OXIDOREDUCTASE	FORMATE HYDROGENLYASE SUBUNIT 2-RELATED				oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3444|UniProtKB=P0CF12	P0CF12	insA6	PTHR47923:SF1	INSERTION ELEMENT IS1 1 PROTEIN INSA-RELATED	INSERTION ELEMENT IS1 1 PROTEIN INSA-RELATED		macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987			
ECOLI|EnsemblGenome=b3456|UniProtKB=P22729	P22729	livM	PTHR30482:SF20	HIGH-AFFINITY BRANCHED-CHAIN AMINO ACID TRANSPORT SYSTEM PERMEASE	HIGH-AFFINITY BRANCHED-CHAIN AMINO ACID TRANSPORT SYSTEM PERMEASE PROTEIN LIVM	carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;branched-chain amino acid transmembrane transporter activity#GO:0015658	branched-chain amino acid transport#GO:0015803;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;nitrogen compound transport#GO:0071705	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b0214|UniProtKB=P0A7Y4	P0A7Y4	rnhA	PTHR10642:SF34	RIBONUCLEASE H1	RIBONUCLEASE HI	hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519	metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;RNA catabolic process#GO:0006401;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;nucleobase-containing compound catabolic process#GO:0034655;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139		RNA metabolism protein#PC00031;endoribonuclease#PC00094	DNA replication#P00017>RNase H#P00538
ECOLI|EnsemblGenome=b3073|UniProtKB=P42588	P42588	patA	PTHR11986:SF112	AMINOTRANSFERASE CLASS III	PUTRESCINE AMINOTRANSFERASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;transaminase activity#GO:0008483	biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;amine metabolic process#GO:0009308;proteinogenic amino acid biosynthetic process#GO:0170038;amine catabolic process#GO:0009310;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;polyamine metabolic process#GO:0006595;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;L-arginine biosynthetic process#GO:0006526;oxoacid metabolic process#GO:0043436;polyamine catabolic process#GO:0006598	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	transaminase#PC00216	
ECOLI|EnsemblGenome=b2746|UniProtKB=P62617	P62617	ispF	PTHR43181:SF1	2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE, CHLOROPLASTIC	2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE	lyase activity#GO:0016829;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824	terpenoid metabolic process#GO:0006721;lipid metabolic process#GO:0006629;isoprenoid biosynthetic process#GO:0008299;metabolic process#GO:0008152;isoprenoid metabolic process#GO:0006720;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;terpenoid biosynthetic process#GO:0016114			
ECOLI|EnsemblGenome=b0535|UniProtKB=P0AEL8	P0AEL8	fimZ	PTHR43214:SF46	TWO-COMPONENT RESPONSE REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR FIMZ	DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090		winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b4262|UniProtKB=P0ADC6	P0ADC6	lptG	PTHR33529:SF2	SLR0882 PROTEIN-RELATED	LIPOPOLYSACCHARIDE EXPORT SYSTEM PERMEASE PROTEIN LPTG		lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;lipid localization#GO:0010876;carbohydrate derivative transport#GO:1901264;transport#GO:0006810	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;ATP-binding cassette (ABC) transporter complex#GO:0043190;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;ATPase dependent transmembrane transport complex#GO:0098533;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495		
ECOLI|EnsemblGenome=b3582|UniProtKB=P37679	P37679	sgbU	PTHR43489:SF1	ISOMERASE	L-RIBULOSE-5-PHOSPHATE 3-EPIMERASE SGBU-RELATED	catalytic activity#GO:0003824;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;racemase and epimerase activity#GO:0016854;isomerase activity#GO:0016853	carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;L-ascorbic acid metabolic process#GO:0019852;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436		isomerase#PC00135;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1427|UniProtKB=P13857	P13857	rimL	PTHR43441:SF11	RIBOSOMAL-PROTEIN-SERINE ACETYLTRANSFERASE	RIBOSOMAL-PROTEIN-SERINE ACETYLTRANSFERASE	protein N-acyltransferase activity#GO:0140186;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740		cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	protein modifying enzyme#PC00260	
ECOLI|EnsemblGenome=b0388|UniProtKB=P0A6E1	P0A6E1	aroL	PTHR21087:SF21	SHIKIMATE KINASE	SHIKIMATE KINASE 2	transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	transferase#PC00220;kinase#PC00137	
ECOLI|EnsemblGenome=b1023|UniProtKB=P75906	P75906	pgaB	PTHR34216:SF7	POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE N-DEACETYLASE-RELATED	POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE N-DEACETYLASE	catalytic activity#GO:0003824;hydrolase activity#GO:0016787				
ECOLI|EnsemblGenome=b3080|UniProtKB=P42592	P42592	ygjK	PTHR23403:SF1	TREHALASE	TREHALASE	hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824	oligosaccharide metabolic process#GO:0009311;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;cellular process#GO:0009987;primary metabolic process#GO:0044238			
ECOLI|EnsemblGenome=b4090|UniProtKB=P37351	P37351	rpiB	PTHR30345:SF7	RIBOSE-5-PHOSPHATE ISOMERASE B	RIBOSE-5-PHOSPHATE ISOMERASE B	intramolecular oxidoreductase activity#GO:0016860;ribose-5-phosphate isomerase activity#GO:0004751;isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861	small molecule catabolic process#GO:0044282;pentose-phosphate shunt, non-oxidative branch#GO:0009052;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;glucose 6-phosphate metabolic process#GO:0051156;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;NADPH regeneration#GO:0006740;glyceraldehyde-3-phosphate metabolic process#GO:0019682;pyridine-containing compound metabolic process#GO:0072524;pentose-phosphate shunt#GO:0006098;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;generation of precursor metabolites and energy#GO:0006091;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152		isomerase#PC00135	
ECOLI|EnsemblGenome=b2203|UniProtKB=P0ABL3	P0ABL3	napB	PTHR38604:SF1	PERIPLASMIC NITRATE REDUCTASE, ELECTRON TRANSFER SUBUNIT	PERIPLASMIC NITRATE REDUCTASE, ELECTRON TRANSFER SUBUNIT		cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;anaerobic respiration#GO:0009061;metabolic process#GO:0008152;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;oxidoreductase complex#GO:1990204;periplasmic space#GO:0042597;catalytic complex#GO:1902494;extracellular region#GO:0005576	reductase#PC00198	
ECOLI|EnsemblGenome=b0174|UniProtKB=P60472	P60472	ispU	PTHR10291:SF47	DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER	DITRANS,POLYCIS-UNDECAPRENYL-DIPHOSPHATE SYNTHASE ((2E,6E)-FARNESYL-DIPHOSPHATE SPECIFIC)	small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;prenyltransferase activity#GO:0004659;metal ion binding#GO:0046872;magnesium ion binding#GO:0000287;cation binding#GO:0043169;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765	isoprenoid metabolic process#GO:0006720;lipid metabolic process#GO:0006629;isoprenoid biosynthetic process#GO:0008299;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;primary metabolic process#GO:0044238	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	acyltransferase#PC00042	
ECOLI|EnsemblGenome=b0515|UniProtKB=P75713	P75713	allE	PTHR34571:SF1	(S)-UREIDOGLYCINE AMINOHYDROLASE	(S)-UREIDOGLYCINE AMINOHYDROLASE	catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810	primary metabolic process#GO:0044238;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144;purine nucleobase catabolic process#GO:0006145;purine-containing compound catabolic process#GO:0072523;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086		hydrolase#PC00121	
ECOLI|EnsemblGenome=b2068|UniProtKB=P04395	P04395	alkA	PTHR43003:SF13	DNA-3-METHYLADENINE GLYCOSYLASE	DNA-3-METHYLADENINE GLYCOSYLASE 2	catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;damaged DNA binding#GO:0003684;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA N-glycosylase activity#GO:0019104;DNA binding#GO:0003677;hydrolase activity#GO:0016787	response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	DNA glycosylase#PC00010	
ECOLI|EnsemblGenome=b1490|UniProtKB=P0AA89	P0AA89	dosC	PTHR45138:SF31	REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM	DIGUANYLATE CYCLASE DGCM-RELATED	nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772	regulation of cellular process#GO:0050794;negative regulation of cell motility#GO:2000146;negative regulation of locomotion#GO:0040013;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;regulation of cell motility#GO:2000145;single-species biofilm formation#GO:0044010;negative regulation of cellular process#GO:0048523;cell adhesion#GO:0007155	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b3103|UniProtKB=P64590	P64590	yhaH	PTHR34980:SF2	INNER MEMBRANE PROTEIN-RELATED-RELATED	INNER MEMBRANE PROTEIN YHAH-RELATED			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b1180|UniProtKB=P76004	P76004	ycgM	PTHR11820:SF115	ACYLPYRUVASE	OXALOACETATE TAUTOMERASE YCGM	catalytic activity#GO:0003824;hydrolase activity#GO:0016787			metabolite interconversion enzyme#PC00262;hydrolase#PC00121	
ECOLI|EnsemblGenome=b0060|UniProtKB=P21189	P21189	polB	PTHR10322:SF36	DNA POLYMERASE CATALYTIC SUBUNIT	DNA POLYMERASE II				DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b2260|UniProtKB=P37353	P37353	menE	PTHR24096:SF442	LONG-CHAIN-FATTY-ACID--COA LIGASE	2-SUCCINYLBENZOATE--COA LIGASE	catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874	ketone metabolic process#GO:0042180;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;menaquinone biosynthetic process#GO:0009234;biosynthetic process#GO:0009058;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283		ligase#PC00142	
ECOLI|EnsemblGenome=b0708|UniProtKB=P00914	P00914	phrB	PTHR11455:SF65	CRYPTOCHROME	DEOXYRIBODIPYRIMIDINE PHOTO-LYASE, MITOCHONDRIAL	catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;nucleotide binding#GO:0000166;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA binding#GO:0003677;ion binding#GO:0043167;deoxyribodipyrimidine photo-lyase activity#GO:0003904;nucleic acid binding#GO:0003676;anion binding#GO:0043168;small molecule binding#GO:0036094	response to light stimulus#GO:0009416;response to stimulus#GO:0050896;response to radiation#GO:0009314;response to abiotic stimulus#GO:0009628		DNA photolyase#PC00014	
ECOLI|EnsemblGenome=b2687|UniProtKB=P45578	P45578	luxS	PTHR35799:SF1	S-RIBOSYLHOMOCYSTEINE LYASE	S-RIBOSYLHOMOCYSTEINE LYASE	lyase activity#GO:0016829;carbon-sulfur lyase activity#GO:0016846;catalytic activity#GO:0003824		intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	lyase#PC00144	
ECOLI|EnsemblGenome=b1868|UniProtKB=P37348	P37348	yecE	PTHR30348:SF9	UNCHARACTERIZED PROTEIN YECE	UPF0759 PROTEIN YECE					
ECOLI|EnsemblGenome=b2813|UniProtKB=P0A935	P0A935	mltA	PTHR30124:SF0	MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE A	MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE A	carbon-oxygen lyase activity, acting on polysaccharides#GO:0016837;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824;peptidoglycan lytic transglycosylase activity#GO:0008933;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835	carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;glycosaminoglycan catabolic process#GO:0006027;aminoglycan metabolic process#GO:0006022;peptidoglycan metabolic process#GO:0000270;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026		glycosidase#PC00110	
ECOLI|EnsemblGenome=b3260|UniProtKB=P0ABT5	P0ABT5	dusB	PTHR11082:SF25	TRNA-DIHYDROURIDINE SYNTHASE	DUS-LIKE FMN-BINDING DOMAIN-CONTAINING PROTEIN				RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b0621|UniProtKB=P0ABP3	P0ABP3	dcuC	PTHR42002:SF2	ANAEROBIC C4-DICARBOXYLATE TRANSPORTER DCUC-RELATED	ANAEROBIC C4-DICARBOXYLATE TRANSPORTER DCUC-RELATED	dicarboxylic acid transmembrane transporter activity#GO:0005310;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;C4-dicarboxylate transmembrane transporter activity#GO:0015556	organic acid transport#GO:0015849;C4-dicarboxylate transport#GO:0015740;carboxylic acid transport#GO:0046942;transport#GO:0006810;dicarboxylic acid transport#GO:0006835;localization#GO:0051179;establishment of localization#GO:0051234	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b2903|UniProtKB=P33195	P33195	gcvP	PTHR11773:SF13	GLYCINE DEHYDROGENASE, DECARBOXYLATING	GLYCINE DEHYDROGENASE (DECARBOXYLATING)	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2812|UniProtKB=Q46927	Q46927	tcdA	PTHR43267:SF1	TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE	TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE	hydro-lyase activity#GO:0016836;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824	tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152		metabolite interconversion enzyme#PC00262;ligase#PC00142	
ECOLI|EnsemblGenome=b2800|UniProtKB=P0AB87	P0AB87	fucA	PTHR22789:SF17	FUCULOSE PHOSPHATE ALDOLASE	L-FUCULOSE PHOSPHATE ALDOLASE	aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824	catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996		aldolase#PC00044;lyase#PC00144	
ECOLI|EnsemblGenome=b0313|UniProtKB=P17446	P17446	betI	PTHR30055:SF234	HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR	HTH-TYPE TRANSCRIPTIONAL REGULATOR BETI	transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141		Tet repressor-like transcription factor#PC00266	
ECOLI|EnsemblGenome=b0877|UniProtKB=P75829	P75829	ybjX	PTHR38785:SF1	HOMOLOG OF VIRK	VIRK PROTEIN					
ECOLI|EnsemblGenome=b4268|UniProtKB=P39208	P39208	idnK	PTHR43442:SF3	GLUCONOKINASE-RELATED	GLUCONOKINASE	phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772	nucleotide metabolic process#GO:0009117;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;oxoacid metabolic process#GO:0043436;pentose-phosphate shunt#GO:0006098;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739		kinase#PC00137	
ECOLI|EnsemblGenome=b1931|UniProtKB=P76318	P76318	yedK	PTHR13604:SF0	DC12-RELATED	ABASIC SITE PROCESSING PROTEIN HMCES	catalytic activity#GO:0003824;binding#GO:0005488;nucleic acid binding#GO:0003676;damaged DNA binding#GO:0003684;single-stranded DNA binding#GO:0003697;lyase activity#GO:0016829;DNA binding#GO:0003677	cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to stress#GO:0033554	chromosome#GO:0005694;replication fork#GO:0005657;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b0447|UniProtKB=P0ACJ5	P0ACJ5	decR	PTHR30154:SF17	LEUCINE-RESPONSIVE REGULATORY PROTEIN	DNA-BINDING TRANSCRIPTIONAL ACTIVATOR DECR	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110		cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b4473|UniProtKB=P30852	P30852	smf	PTHR43022:SF1	PROTEIN SMF	PROTEIN SMF	catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697				
ECOLI|EnsemblGenome=b2386|UniProtKB=P77579	P77579	fryC	PTHR30505:SF0	FRUCTOSE-LIKE PERMEASE	FRUCTOSE-LIKE PTS SYSTEM EIIBC COMPONENT-RELATED	protein-phosphocysteine-sugar phosphotransferase activity#GO:0090563;carbohydrate transmembrane transporter activity#GO:0015144;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;active transmembrane transporter activity#GO:0022804	transport#GO:0006810;carbohydrate transport#GO:0008643;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;import into cell#GO:0098657;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b3231|UniProtKB=P0AA10	P0AA10	rplM	PTHR11545:SF2	RIBOSOMAL PROTEIN L13	LARGE RIBOSOMAL SUBUNIT PROTEIN UL13C	structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735	negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of translation#GO:0017148;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608	intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribosome#GO:0005840	translational protein#PC00263;ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b2307|UniProtKB=P0AEU3	P0AEU3	hisM	PTHR30450:SF5	ABC TRANSPORTER PERMEASE	HISTIDINE_LYSINE_ARGININE_ORNITHINE TRANSPORT SYSTEM PERMEASE PROTEIN HISM		transport#GO:0006810;amino acid transport#GO:0006865;localization#GO:0051179;establishment of localization#GO:0051234	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b4376|UniProtKB=P0AFH8	P0AFH8	osmY	PTHR34606:SF11	BON DOMAIN-CONTAINING PROTEIN	OSMOTICALLY-INDUCIBLE PROTEIN Y					
ECOLI|EnsemblGenome=b2200|UniProtKB=P0ABL8	P0ABL8	ccmB	PTHR30070:SF2	HEME EXPORTER PROTEIN B	HEME EXPORTER PROTEIN B		cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;metabolic process#GO:0008152;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0184|UniProtKB=P10443	P10443	dnaE	PTHR32294:SF0	DNA POLYMERASE III SUBUNIT ALPHA	DNA POLYMERASE III SUBUNIT ALPHA	transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;DNA-directed DNA polymerase activity#GO:0003887			DNA metabolism protein#PC00009;DNA-directed DNA polymerase#PC00018	
ECOLI|EnsemblGenome=b2197|UniProtKB=P69490	P69490	ccmE	PTHR34128:SF3	CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCME HOMOLOG, MITOCHONDRIAL	CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCME	binding#GO:0005488;heme binding#GO:0020037;tetrapyrrole binding#GO:0046906	protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;metabolic process#GO:0008152;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987			
ECOLI|EnsemblGenome=b1191|UniProtKB=P76007	P76007	cvrA	PTHR32507:SF7	NA(+)/H(+) ANTIPORTER 1	K(+)_H(+) ANTIPORTER NHAP2	monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297	homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;potassium ion homeostasis#GO:0055075;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878			
ECOLI|EnsemblGenome=b4337|UniProtKB=P39386	P39386	mdtM	PTHR23502:SF10	MAJOR FACILITATOR SUPERFAMILY	MULTIDRUG RESISTANCE PROTEIN MDTM	active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;monoatomic cation transmembrane transporter activity#GO:0008324	transport#GO:0006810;xenobiotic transport#GO:0042908;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;xenobiotic detoxification by transmembrane export across the plasma membrane#GO:1990961;cellular process#GO:0009987;detoxification#GO:0098754;export from cell#GO:0140352;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to toxic substance#GO:0009636	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b3189|UniProtKB=P0A749	P0A749	murA	PTHR43783:SF4	UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE	UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765	biosynthetic process#GO:0009058;cell wall organization or biogenesis#GO:0071554;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;cell wall macromolecule biosynthetic process#GO:0044038;cellular component biogenesis#GO:0044085;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycosaminoglycan biosynthetic process#GO:0006024;cellular component organization or biogenesis#GO:0071840;peptidoglycan-based cell wall biogenesis#GO:0009273;metabolic process#GO:0008152;peptidoglycan metabolic process#GO:0000270;peptidoglycan biosynthetic process#GO:0009252;glycosaminoglycan metabolic process#GO:0030203;aminoglycan biosynthetic process#GO:0006023;cell wall macromolecule metabolic process#GO:0044036;cell wall biogenesis#GO:0042546;aminoglycan metabolic process#GO:0006022	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	transferase#PC00220	
ECOLI|EnsemblGenome=b3551|UniProtKB=P20099	P20099	bisC	PTHR43742:SF5	TRIMETHYLAMINE-N-OXIDE REDUCTASE	BIOTIN SULFOXIDE REDUCTASE	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;anaerobic respiration#GO:0009061;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980	cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;extracellular region#GO:0005576;periplasmic space#GO:0042597	reductase#PC00198	
ECOLI|EnsemblGenome=b1466|UniProtKB=P19317	P19317	narW	PTHR43680:SF4	NITRATE REDUCTASE MOLYBDENUM COFACTOR ASSEMBLY CHAPERONE	NITRATE REDUCTASE MOLYBDENUM COFACTOR ASSEMBLY CHAPERONE NARW-RELATED	molecular carrier activity#GO:0140104	cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nitrate metabolic process#GO:0042126;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;chaperone-mediated protein complex assembly#GO:0051131;cellular component assembly#GO:0022607;small molecule metabolic process#GO:0044281;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987		chaperone#PC00072	
ECOLI|EnsemblGenome=b1517|UniProtKB=P76143	P76143	lsrF	PTHR47916:SF1	FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 1	3-HYDROXY-5-PHOSPHONOOXYPENTANE-2,4-DIONE THIOLASE	acyltransferase activity#GO:0016746;lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832;transferase activity#GO:0016740;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;fructose-bisphosphate aldolase activity#GO:0004332;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747			aldolase#PC00044;lyase#PC00144	
ECOLI|EnsemblGenome=b3910|UniProtKB=P32157	P32157	yiiM	PTHR30212:SF5	PROTEIN YIIM	6-HYDROXYLAMINOPURINE REDUCTASE YIIM	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	response to stimulus#GO:0050896;catabolic process#GO:0009056;response to chemical#GO:0042221;response to toxic substance#GO:0009636;detoxification#GO:0098754;cellular process#GO:0009987;secondary metabolic process#GO:0019748;metabolic process#GO:0008152	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		
ECOLI|EnsemblGenome=b0961|UniProtKB=P0AB12	P0AB12	yccF	PTHR42903:SF1	INNER MEMBRANE PROTEIN YCCF	INNER MEMBRANE PROTEIN YCCF			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b1055|UniProtKB=P24188	P24188	trhO	PTHR43846:SF2	UPF0176 PROTEIN YCEA	TRNA URIDINE(34) HYDROXYLASE	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187			
ECOLI|EnsemblGenome=b2537|UniProtKB=Q47141	Q47141	hcaR	PTHR30346:SF0	TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED	HCA OPERON TRANSCRIPTIONAL ACTIVATOR HCAR	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252	protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993	winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b0767|UniProtKB=P52697	P52697	pgl	PTHR30344:SF8	6-PHOSPHOGLUCONOLACTONASE-RELATED	6-PHOSPHOGLUCONOLACTONASE	hydrolase activity#GO:0016787;6-phosphogluconolactonase activity#GO:0017057;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788	generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nucleobase-containing compound metabolic process#GO:0006139;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;pentose-phosphate shunt#GO:0006098;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;hydrolase#PC00121	
ECOLI|EnsemblGenome=b1114|UniProtKB=P30958	P30958	mfd	PTHR14025:SF34	FANCONI ANEMIA GROUP M FANCM FAMILY MEMBER	TRANSCRIPTION-REPAIR-COUPLING FACTOR	ATP-dependent activity#GO:0140657;DNA translocase activity#GO:0015616;enzyme binding#GO:0019899;binding#GO:0005488;nucleic acid binding#GO:0003676;protein binding#GO:0005515;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;RNA polymerase binding#GO:0070063;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA polymerase core enzyme binding#GO:0043175;catalytic activity, acting on DNA#GO:0140097	cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;cellular response to stress#GO:0033554;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;chromosome organization#GO:0051276;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840		DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b1130|UniProtKB=P23836	P23836	phoP	PTHR48111:SF71	REGULATOR OF RPOS	TRANSCRIPTIONAL REGULATORY PROTEIN PHOP	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;double-stranded DNA binding#GO:0003690	regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;cytosol#GO:0005829	helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b3644|UniProtKB=P23839	P23839	yicC	PTHR30636:SF3	UPF0701 PROTEIN YICC	ENDORIBONUCLEASE YICC	hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540	RNA catabolic process#GO:0006401;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056			
ECOLI|EnsemblGenome=b1623|UniProtKB=P22333	P22333	add	PTHR11409:SF43	ADENOSINE DEAMINASE	ADENOSINE DEAMINASE	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;adenosine deaminase activity#GO:0004000;catalytic activity#GO:0003824	catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;nucleobase-containing small molecule catabolic process#GO:0034656;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;nucleoside catabolic process#GO:0009164;purine-containing compound biosynthetic process#GO:0072522;purine nucleoside metabolic process#GO:0042278;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;adenosine metabolic process#GO:0046085;cellular process#GO:0009987;purine-containing compound catabolic process#GO:0072523;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;nucleobase metabolic process#GO:0009112;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine nucleobase metabolic process#GO:0006144;small molecule biosynthetic process#GO:0044283	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	deaminase#PC00088	Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine deaminase#P02807;Adenine and hypoxanthine salvage pathway#P02723>Adenosine deaminase#P02811
ECOLI|EnsemblGenome=b1754|UniProtKB=P76223	P76223	ynjB	PTHR42779:SF1	PROTEIN YNJB	PROTEIN YNJB					
ECOLI|EnsemblGenome=b3715|UniProtKB=P31467	P31467	yieH	PTHR46193:SF10	6-PHOSPHOGLUCONATE PHOSPHATASE	6-PHOSPHOGLUCONATE PHOSPHATASE	catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787			metabolite interconversion enzyme#PC00262;phosphatase#PC00181	
ECOLI|EnsemblGenome=b0659|UniProtKB=P0A898	P0A898	ybeY	PTHR46986:SF1	ENDORIBONUCLEASE YBEY, CHLOROPLASTIC	ENDORIBONUCLEASE YBEY ISOFORM 1	nuclease activity#GO:0004518;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824			endoribonuclease#PC00094	
ECOLI|EnsemblGenome=b0566|UniProtKB=P10805	P10805	envY	PTHR43280:SF20	ARAC-FAMILY TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR ADIY-RELATED	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690	regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222		helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b1469|UniProtKB=P37758	P37758	narU	PTHR23515:SF6	HIGH-AFFINITY NITRATE TRANSPORTER 2.3	NITRATE_NITRITE TRANSPORTER NARU				transporter#PC00227	
ECOLI|EnsemblGenome=b2721|UniProtKB=P16431	P16431	hycE	PTHR43485:SF1	HYDROGENASE-4 COMPONENT G	FORMATE HYDROGENLYASE SUBUNIT 5-RELATED		metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;anaerobic electron transport chain#GO:0019645;anaerobic respiration#GO:0009061		oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b4082|UniProtKB=P32716	P32716	mdtN	PTHR30367:SF1	P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT AAEA-RELATED	MULTIDRUG RESISTANCE PROTEIN MDTN	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085			
ECOLI|EnsemblGenome=b1488|UniProtKB=P77790	P77790	ddpX	PTHR43126:SF1	D-ALANYL-D-ALANINE DIPEPTIDASE	D-ALANYL-D-ALANINE DIPEPTIDASE					
ECOLI|EnsemblGenome=b4361|UniProtKB=P0AEF0	P0AEF0	dnaC	PTHR30050:SF9	CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA	REPLICATIVE HELICASE LOADER DNAC	sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA replication origin binding#GO:0003688	nucleobase-containing compound metabolic process#GO:0006139;DNA replication#GO:0006260;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;DNA metabolic process#GO:0006259		DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b3619|UniProtKB=P67910	P67910	hldD	PTHR43103:SF8	NUCLEOSIDE-DIPHOSPHATE-SUGAR EPIMERASE	ADP-L-GLYCERO-D-MANNO-HEPTOSE-6-EPIMERASE	catalytic activity#GO:0003824;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;racemase and epimerase activity#GO:0016854;isomerase activity#GO:0016853	primary metabolic process#GO:0044238;liposaccharide metabolic process#GO:1903509;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;lipopolysaccharide core region biosynthetic process#GO:0009244;lipopolysaccharide biosynthetic process#GO:0009103;polysaccharide biosynthetic process#GO:0000271;lipopolysaccharide metabolic process#GO:0008653;oligosaccharide biosynthetic process#GO:0009312;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;oligosaccharide metabolic process#GO:0009311		epimerase/racemase#PC00096	
ECOLI|EnsemblGenome=b2052|UniProtKB=P32055	P32055	fcl	PTHR43238:SF1	GDP-L-FUCOSE SYNTHASE	GDP-L-FUCOSE SYNTHASE	catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1107|UniProtKB=P75949	P75949	nagZ	PTHR30480:SF13	BETA-HEXOSAMINIDASE-RELATED	BETA-HEXOSAMINIDASE	catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787	glycosaminoglycan metabolic process#GO:0030203;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;peptidoglycan turnover#GO:0009254;aminoglycan metabolic process#GO:0006022;peptidoglycan metabolic process#GO:0000270;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	hydrolase#PC00121	
ECOLI|EnsemblGenome=b3017|UniProtKB=P26648	P26648	ftsP	PTHR11709:SF350	MULTI-COPPER OXIDASE	CELL DIVISION PROTEIN FTSP	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491		outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;periplasmic space#GO:0042597;extracellular region#GO:0005576	oxidase#PC00175	
ECOLI|EnsemblGenome=b3637|UniProtKB=P0A7M2	P0A7M2	rpmB	PTHR13528:SF4	39S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL	LARGE RIBOSOMAL SUBUNIT PROTEIN BL28	structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735		intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165	ribosomal protein#PC00202;translational protein#PC00263	
ECOLI|EnsemblGenome=b0598|UniProtKB=P15078	P15078	cstA	PTHR30252:SF2	INNER MEMBRANE PEPTIDE TRANSPORTER	PEPTIDE TRANSPORTER CSTA	monocarboxylic acid transmembrane transporter activity#GO:0008028;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291	response to stimulus#GO:0050896;carboxylic acid transmembrane transport#GO:1905039;response to nutrient levels#GO:0031667;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;cellular response to nutrient levels#GO:0031669	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b2351|UniProtKB=P77293	P77293	yfdH	PTHR48090:SF1	UNDECAPRENYL-PHOSPHATE 4-DEOXY-4-FORMAMIDO-L-ARABINOSE TRANSFERASE-RELATED	PROPHAGE BACTOPRENOL GLUCOSYL TRANSFERASE HOMOLOG			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transferase#PC00220;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1323|UniProtKB=P07604	P07604	tyrR	PTHR32071:SF3	TRANSCRIPTIONAL REGULATORY PROTEIN	HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN TYRR	binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604	protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991	DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b3152|UniProtKB=P45469	P45469	yraR	PTHR14097:SF10	OXIDOREDUCTASE HTATIP2	NAD(P)-BINDING PROTEIN YRAR-RELATED				oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2105|UniProtKB=P64530	P64530	rcnR	PTHR33677:SF1	TRANSCRIPTIONAL REPRESSOR FRMR-RELATED	TRANSCRIPTIONAL REPRESSOR RCNR	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription repressor activity#GO:0001217;double-stranded DNA binding#GO:0003690	negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794	protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993	DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b0926|UniProtKB=P0AB06	P0AB06	mepK	PTHR37425:SF1	PEPTIDOGLYCAN L,D-ENDOPEPTIDASE MEPK	PEPTIDOGLYCAN L,D-ENDOPEPTIDASE MEPK	catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824	macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;peptidoglycan metabolic process#GO:0000270;peptidoglycan turnover#GO:0009254;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987	cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;extracellular region#GO:0005576;periplasmic space#GO:0042597		
ECOLI|EnsemblGenome=b1131|UniProtKB=P0AB89	P0AB89	purB	PTHR43411:SF7	ADENYLOSUCCINATE LYASE	ADENYLOSUCCINATE LYASE	lyase activity#GO:0016829;catalytic activity#GO:0003824	nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide metabolic process#GO:0009117;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	lyase#PC00144	De novo purine biosynthesis#P02738>Adenosuccinate lyase#P02901;De novo purine biosynthesis#P02738>5-Phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole lyase#P02892
ECOLI|EnsemblGenome=b3553|UniProtKB=P37666	P37666	ghrB	PTHR10996:SF283	2-HYDROXYACID DEHYDROGENASE-RELATED	GLYOXYLATE_HYDROXYPYRUVATE REDUCTASE B	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	Serine glycine biosynthesis#P02776>Phosphoglycerate dehydrogenase#P03160
ECOLI|EnsemblGenome=b0376|UniProtKB=P0AD70	P0AD70	ampH	PTHR46825:SF9	D-ALANYL-D-ALANINE-CARBOXYPEPTIDASE/ENDOPEPTIDASE AMPH	BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN				hydrolase#PC00121;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0486|UniProtKB=P77400	P77400	ybaT	PTHR42770:SF11	AMINO ACID TRANSPORTER-RELATED	INNER MEMBRANE TRANSPORT PROTEIN YBAT	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227;amino acid transporter#PC00046;secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b0616|UniProtKB=P0A9I1	P0A9I1	citE	PTHR32308:SF10	LYASE BETA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13030)-RELATED	CITRATE LYASE SUBUNIT BETA		small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152	protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494	metabolite interconversion enzyme#PC00262;lyase#PC00144	Pyruvate metabolism#P02772>Citrate Lyase#P03137
ECOLI|EnsemblGenome=b3594|UniProtKB=P0ADK6	P0ADK6	yibA	PTHR12697:SF5	PBS LYASE HEAT-LIKE PROTEIN	DEOXYHYPUSINE HYDROXYLASE	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824			lyase#PC00144	
ECOLI|EnsemblGenome=b3673|UniProtKB=P31442	P31442	emrD	PTHR23502:SF32	MAJOR FACILITATOR SUPERFAMILY	MULTIDRUG RESISTANCE PROTEIN D	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	xenobiotic transport#GO:0042908;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;xenobiotic detoxification by transmembrane export across the plasma membrane#GO:1990961;cellular process#GO:0009987;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to toxic substance#GO:0009636;export from cell#GO:0140352;detoxification#GO:0098754	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b1723|UniProtKB=P06999	P06999	pfkB	PTHR46566:SF2	1-PHOSPHOFRUCTOKINASE-RELATED	ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE ISOZYME 2	phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200		cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	transferase#PC00220;kinase#PC00137	
ECOLI|EnsemblGenome=b1790|UniProtKB=P76241	P76241	nimR	PTHR11019:SF199	HTH-TYPE TRANSCRIPTIONAL REGULATOR NIMR	HTH-TYPE TRANSCRIPTIONAL REGULATOR NIMR				DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b2243|UniProtKB=P0A996	P0A996	glpC	PTHR32479:SF19	GLYCOLATE OXIDASE IRON-SULFUR SUBUNIT	ANAEROBIC GLYCEROL-3-PHOSPHATE DEHYDROGENASE SUBUNIT C	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614	cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;anaerobic respiration#GO:0009061;electron transport chain#GO:0022900;metabolic process#GO:0008152;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0697|UniProtKB=P03960	P03960	kdpB	PTHR43743:SF1	POTASSIUM-TRANSPORTING ATPASE ATP-BINDING SUBUNIT	POTASSIUM-TRANSPORTING ATPASE ATP-BINDING SUBUNIT	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;metal ion transmembrane transporter activity#GO:0046873;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324	transport#GO:0006810;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813	cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;cation-transporting ATPase complex#GO:0090533;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533	primary active transporter#PC00068;transporter#PC00227	
ECOLI|EnsemblGenome=b0452|UniProtKB=P0AGG2	P0AGG2	tesB	PTHR11066:SF68	ACYL-COA THIOESTERASE	ACYL-COA THIOESTERASE 2	hydrolase activity#GO:0016787;deacylase activity#GO:0160215;acyl-CoA hydrolase activity#GO:0016289;catalytic activity#GO:0003824;fatty acyl-CoA hydrolase activity#GO:0047617;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790	nucleobase-containing compound metabolic process#GO:0006139;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436		esterase#PC00097;hydrolase#PC00121;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0133|UniProtKB=P31663	P31663	panC	PTHR21299:SF1	CYTIDYLATE KINASE/PANTOATE-BETA-ALANINE LIGASE	PANTOATE--BETA-ALANINE LIGASE	ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879	monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752			Pantothenate biosynthesis#P02761>Pantoate-beta-alanine ligase#P03068
ECOLI|EnsemblGenome=b1278|UniProtKB=P0A924	P0A924	pgpB	PTHR14969:SF54	SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE	PHOSPHATIDYLGLYCEROPHOSPHATASE B			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	hydrolase#PC00121;phosphatase#PC00181	
ECOLI|EnsemblGenome=b3256|UniProtKB=P24182	P24182	accC	PTHR48095:SF2	PYRUVATE CARBOXYLASE SUBUNIT A	BIOTIN CARBOXYLASE, CHLOROPLASTIC	ligase activity#GO:0016874;catalytic activity#GO:0003824	monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394			
ECOLI|EnsemblGenome=b0195|UniProtKB=P28634	P28634	trmO	PTHR12818:SF0	TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE	TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE	tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757				
ECOLI|EnsemblGenome=b1604|UniProtKB=P76177	P76177	ydgH	PTHR34156:SF2	OUTER MEMBRANE PROTEIN-RELATED-RELATED	PROTEIN YDGH		response to stress#GO:0006950;response to stimulus#GO:0050896			
ECOLI|EnsemblGenome=b3364|UniProtKB=P60778	P60778	tsgA	PTHR43702:SF14	L-FUCOSE-PROTON SYMPORTER	PROTEIN TSGA	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b4394|UniProtKB=P39411	P39411	yjjX	PTHR34699:SF2	FAMILY NOT NAMED	INOSINE_XANTHOSINE TRIPHOSPHATASE					
ECOLI|EnsemblGenome=b3863|UniProtKB=P00582	P00582	polA	PTHR10133:SF27	DNA POLYMERASE I	HELICASE AND POLYMERASE-CONTAINING PROTEIN TEBICHI	transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;DNA-directed DNA polymerase activity#GO:0003887	cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170		DNA-directed DNA polymerase#PC00018	
ECOLI|EnsemblGenome=b3497|UniProtKB=P68567	P68567	rsmJ	PTHR36112:SF1	RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE J	RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE J	catalytic activity, acting on a rRNA#GO:0140102;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;catalytic activity, acting on RNA#GO:0140098;rRNA (guanine) methyltransferase activity#GO:0016435;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741	RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;methylation#GO:0032259;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA modification#GO:0000154;rRNA methylation#GO:0031167;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;rRNA base methylation#GO:0070475;macromolecule biosynthetic process#GO:0009059		RNA metabolism protein#PC00031;RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b4033|UniProtKB=P02916	P02916	malF	PTHR47314:SF1	MALTOSE/MALTODEXTRIN TRANSPORT SYSTEM PERMEASE PROTEIN MALF	MALTOSE_MALTODEXTRIN TRANSPORT SYSTEM PERMEASE PROTEIN MALF	ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399	transport#GO:0006810;carbohydrate transport#GO:0008643;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;localization#GO:0051179	transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;ATP-binding cassette (ABC) transporter complex#GO:0043190;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b3145|UniProtKB=P43319	P43319	yraK	PTHR33420:SF31	FIMBRIAL SUBUNIT ELFA-RELATED	PROTEIN LPFD		cell-substrate adhesion#GO:0031589;single-species biofilm formation#GO:0044010;cell adhesion#GO:0007155;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;cell projection#GO:0042995		
ECOLI|EnsemblGenome=b3572|UniProtKB=P09053	P09053	avtA	PTHR42790:SF4	AMINOTRANSFERASE	VALINE--PYRUVATE AMINOTRANSFERASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	transaminase#PC00216	
ECOLI|EnsemblGenome=b4474|UniProtKB=P45541	P45541	frlC	PTHR43489:SF14	ISOMERASE	FRUCTOSELYSINE 3-EPIMERASE-RELATED	intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861	carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;glyoxylate metabolic process#GO:0046487;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436		metabolite interconversion enzyme#PC00262;isomerase#PC00135	
ECOLI|EnsemblGenome=b4302|UniProtKB=P39363	P39363	sgcA	PTHR36203:SF3	ASCORBATE-SPECIFIC PTS SYSTEM EIIA COMPONENT	PHOSPHOTRANSFERASE IIA COMPONENT SGCA-RELATED	active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;carbohydrate transmembrane transporter activity#GO:0015144;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein-phosphocysteine-sugar phosphotransferase activity#GO:0090563	carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739;cellular process#GO:0009987;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;transmembrane transport#GO:0055085;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;carbohydrate transport#GO:0008643			
ECOLI|EnsemblGenome=b3390|UniProtKB=P0A6D7	P0A6D7	aroK	PTHR21087:SF16	SHIKIMATE KINASE	SHIKIMATE KINASE 1	phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772		cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	kinase#PC00137;transferase#PC00220	Chorismate biosynthesis#P02734>Shikimate kinase#P02874
ECOLI|EnsemblGenome=b3983|UniProtKB=P0A7J7	P0A7J7	rplK	PTHR11661:SF49	60S RIBOSOMAL PROTEIN L12	50S RIBOSOMAL PROTEIN L11-LIKE-RELATED	structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;structural constituent of ribosome#GO:0003735	gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412	intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625	ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b2179|UniProtKB=P33915	P33915	yejE	PTHR30325:SF0	MEMBRANE COMPONENT OF ABC TRANSPORTER	OLIGOPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN YEJE		oligopeptide transmembrane transport#GO:0035672;cellular process#GO:0009987;peptide transport#GO:0015833;nitrogen compound transport#GO:0071705;oligopeptide transport#GO:0006857;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b3078|UniProtKB=P42590	P42590	ygjI	PTHR42770:SF15	AMINO ACID TRANSPORTER-RELATED	GLUTAMATE_GAMMA-AMINOBUTYRATE ANTIPORTER-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	amino acid transporter#PC00046;secondary carrier transporter#PC00258;transporter#PC00227	
ECOLI|EnsemblGenome=b1770|UniProtKB=P77721	P77721	ydjF	PTHR30363:SF62	HTH-TYPE TRANSCRIPTIONAL REGULATOR SRLR-RELATED	GLUCITOL OPERON REPRESSOR	transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789		DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b0841|UniProtKB=P75806	P75806	ybjG	PTHR14969:SF62	SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE	UNDECAPRENYL-DIPHOSPHATASE YBJG-RELATED				hydrolase#PC00121;phosphatase#PC00181	
ECOLI|EnsemblGenome=b1118|UniProtKB=P75958	P75958	lolE	PTHR30489:SF0	LIPOPROTEIN-RELEASING SYSTEM TRANSMEMBRANE PROTEIN LOLE	LIPOPROTEIN-RELEASING SYSTEM TRANSMEMBRANE PROTEIN LOLE		macromolecule localization#GO:0033036;cellular process#GO:0009987;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797		
ECOLI|EnsemblGenome=b0109|UniProtKB=P30011	P30011	nadC	PTHR32179:SF6	NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING]	NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING]	glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763	purine nucleotide biosynthetic process#GO:0006164;oxoacid metabolic process#GO:0043436;purine-containing compound biosynthetic process#GO:0072522;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nicotinamide nucleotide metabolic process#GO:0046496;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1076|UniProtKB=P75937	P75937	flgE	PTHR30435:SF1	FLAGELLAR PROTEIN	FLAGELLAR HOOK PROTEIN FLGE		cilium or flagellum-dependent cell motility#GO:0001539;cellular process#GO:0009987;archaeal or bacterial-type flagellum-dependent cell motility#GO:0097588;bacterial-type flagellum-dependent swarming motility#GO:0071978;bacterial-type flagellum-dependent cell motility#GO:0071973;cell motility#GO:0048870	membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;organelle#GO:0043226;bacterial-type flagellum#GO:0009288;cytoplasm#GO:0005737;cell projection#GO:0042995;cytosol#GO:0005829	structural protein#PC00211	
ECOLI|EnsemblGenome=b4188|UniProtKB=P0AF82	P0AF82	yjfN	PTHR34156:SF4	OUTER MEMBRANE PROTEIN-RELATED-RELATED	INNER MEMBRANE PROTEIN		response to stimulus#GO:0050896;response to stress#GO:0006950			
ECOLI|EnsemblGenome=b2991|UniProtKB=P0A703	P0A703	hybF	PTHR34535:SF4	HYDROGENASE MATURATION FACTOR HYPA	HYDROGENASE MATURATION FACTOR HYBF	metal ion binding#GO:0046872;cation binding#GO:0043169;zinc ion binding#GO:0008270;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914	biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152			
ECOLI|EnsemblGenome=b3068|UniProtKB=P0A9H1	P0A9H1	mug	PTHR12159:SF12	G/T AND G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE	G_U MISMATCH-SPECIFIC URACIL DNA GLYCOSYLASE	hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA N-glycosylase activity#GO:0019104	DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139		DNA metabolism protein#PC00009;DNA glycosylase#PC00010	
ECOLI|EnsemblGenome=b4019|UniProtKB=P13009	P13009	metH	PTHR45833:SF1	METHIONINE SYNTHASE	METHIONINE SYNTHASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741	proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;aspartate family amino acid biosynthetic process#GO:0009067;proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;tetrahydrofolate metabolic process#GO:0046653;oxoacid metabolic process#GO:0043436	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		S-adenosylmethionine biosynthesis#P02773>Cobalamin-dependent homocysteine transmethylase#P03142;Formyltetrahydrofolate biosynthesis#P02743>Cobalamin dependent homocysteine transmethylase#P02953;Methionine biosynthesis#P02753>Homocysteine transmethylase#P03024
ECOLI|EnsemblGenome=b0448|UniProtKB=P77265	P77265	mdlA	PTHR24221:SF300	ATP-BINDING CASSETTE SUB-FAMILY B	MULTIDRUG RESISTANCE-LIKE ATP-BINDING PROTEIN MDLA	ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399	transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179		ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b3348|UniProtKB=P0A8R4	P0A8R4	slyX	PTHR36508:SF1	PROTEIN SLYX	PROTEIN SLYX					
ECOLI|EnsemblGenome=b2599|UniProtKB=P0A9J8	P0A9J8	pheA	PTHR21022:SF19	PREPHENATE DEHYDRATASE  P PROTEIN	PREPHENATE DEHYDRATASE-RELATED	catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829	cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;aromatic amino acid biosynthetic process#GO:0009073;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	lyase#PC00144;dehydratase#PC00091	Phenylalanine biosynthesis#P02765>Prephenate dehydratase#P03099
ECOLI|EnsemblGenome=b4364|UniProtKB=P0ADD5	P0ADD5	yjjP	PTHR34390:SF2	UPF0442 PROTEIN YJJB-RELATED	SUCCINATE TRANSPORTER SUBUNIT YJJP-RELATED		establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;succinate transport#GO:0015744;dicarboxylic acid transport#GO:0006835	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b4378|UniProtKB=P39408	P39408	yjjV	PTHR46124:SF3	D-AMINOACYL-TRNA DEACYLASE	HYDROLASE, TATD FAMILY			cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b3600|UniProtKB=P09424	P09424	mtlD	PTHR30524:SF0	MANNITOL-1-PHOSPHATE 5-DEHYDROGENASE	ALTRONATE OXIDOREDUCTASE-RELATED	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3555|UniProtKB=P0A9V5	P0A9V5	yiaG	PTHR36511:SF6	MERR FAMILY BACTERIAL REGULATORY PROTEIN	TRANSCRIPTIONAL REGULATOR	binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222		Lambda repressor-like transcription factor#PC00245	
ECOLI|EnsemblGenome=b0406|UniProtKB=P0A847	P0A847	tgt	PTHR46499:SF1	QUEUINE TRNA-RIBOSYLTRANSFERASE	QUEUINE TRNA-RIBOSYLTRANSFERASE		macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble base modification#GO:0002097;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	RNA metabolism protein#PC00031;RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b0006|UniProtKB=P0A8I3	P0A8I3	yaaA	PTHR30283:SF4	PEROXIDE STRESS RESPONSE PROTEIN YAAA	DNA-BINDING AND PEROXIDE STRESS RESISTANCE PROTEIN YAAA		response to oxidative stress#GO:0006979;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;response to stress#GO:0006950			
ECOLI|Gene_OrderedLocusName=b1459|UniProtKB=P76119	P76119	yncI	PTHR30298:SF0	H REPEAT-ASSOCIATED PREDICTED TRANSPOSASE	PROTEIN YBFL-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b1819|UniProtKB=P69805	P69805	manZ	PTHR32502:SF5	N-ACETYLGALACTOSAMINE PERMEASE II COMPONENT-RELATED	N-ACETYLGALACTOSAMINE PERMEASE IID COMPONENT-RELATED	phosphotransferase activity, alcohol group as acceptor#GO:0016773;carbohydrate transmembrane transporter activity#GO:0015144;transferase activity#GO:0016740;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transferase activity, transferring phosphorus-containing groups#GO:0016772;sugar transmembrane transporter activity#GO:0051119;active transmembrane transporter activity#GO:0022804	carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739;cellular process#GO:0009987;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;import into cell#GO:0098657;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;carbohydrate transport#GO:0008643	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b2171|UniProtKB=P0A6N8	P0A6N8	efpL	PTHR30053:SF14	ELONGATION FACTOR P	TRANSLATION ELONGATION FACTOR KOW-LIKE DOMAIN-CONTAINING PROTEIN	translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051		cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	translation elongation factor#PC00222;translation factor#PC00223;translational protein#PC00263	
ECOLI|EnsemblGenome=b2162|UniProtKB=P33022	P33022	rihB	PTHR12304:SF61	INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE	PYRIMIDINE-SPECIFIC RIBONUCLEOSIDE HYDROLASE RIHA-RELATED	catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787	metabolic process#GO:0008152;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;purine nucleoside metabolic process#GO:0042278;nucleoside catabolic process#GO:0009164;nucleobase-containing small molecule catabolic process#GO:0034656;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside metabolic process#GO:0009116;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	hydrolase#PC00121	
ECOLI|EnsemblGenome=b0423|UniProtKB=P77718	P77718	thiI	PTHR43209:SF1	TRNA SULFURTRANSFERASE	TRNA SULFURTRANSFERASE	sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740	nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;tRNA thio-modification#GO:0034227;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033	cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;sulfurtransferase complex#GO:1990228;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622	RNA processing factor#PC00147;RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b4293|UniProtKB=P23484	P23484	fecI	PTHR43133:SF63	RNA POLYMERASE ECF-TYPE SIGMA FACTO	FERRIC CITRATE UPTAKE SIGMA FACTOR FECI	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355		DNA-binding transcription factor#PC00218;Sigma factor#PC00267;helix-turn-helix transcription factor#PC00116	
ECOLI|Gene_OrderedLocusName=JW5812|UniProtKB=Q47154	Q47154	lafU	PTHR30329:SF22	STATOR ELEMENT OF FLAGELLAR MOTOR COMPLEX	TRUNCATED FLAGELLAR EXPORT_ASSEMBLY PROTEIN LAFU-RELATED		cell motility#GO:0048870;bacterial-type flagellum-dependent cell motility#GO:0071973;bacterial-type flagellum-dependent swarming motility#GO:0071978;archaeal or bacterial-type flagellum-dependent cell motility#GO:0097588;cellular process#GO:0009987;cilium or flagellum-dependent cell motility#GO:0001539	membraneless organelle#GO:0043228;plasma membrane#GO:0005886;cell projection#GO:0042995;bacterial-type flagellum#GO:0009288;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020	structural protein#PC00211	
ECOLI|EnsemblGenome=b0324|UniProtKB=P77554	P77554	yahJ	PTHR32027:SF0	CYTOSINE DEAMINASE	CYTOSINE DEAMINASE	catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814	primary metabolic process#GO:0044238;pyrimidine nucleobase catabolic process#GO:0006208;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;pyrimidine nucleobase metabolic process#GO:0006206;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086		deaminase#PC00088	Salvage pyrimidine ribonucleotides#P02775>Cytosine deaminase#P03155
ECOLI|EnsemblGenome=b3803|UniProtKB=P09127	P09127	hemX	PTHR38043:SF1	PROTEIN HEMX	PROTEIN HEMX					
ECOLI|EnsemblGenome=b0480|UniProtKB=P07024	P07024	ushA	PTHR11575:SF46	5'-NUCLEOTIDASE-RELATED	PROTEIN USHA	5'-nucleotidase activity#GO:0008253;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578		extracellular region#GO:0005576;periplasmic space#GO:0042597;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313	hydrolase#PC00121;phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3726|UniProtKB=P07654	P07654	pstA	PTHR42922:SF1	PHOSPHATE TRANSPORT SYSTEM PERMEASE PROTEIN PSTA	PHOSPHATE TRANSPORT SYSTEM PERMEASE PROTEIN PSTA	phosphate transmembrane transporter activity#GO:0005315;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804	transport#GO:0006810;cellular process#GO:0009987;phosphate ion transport#GO:0006817;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179		transporter#PC00227	
ECOLI|EnsemblGenome=b0572|UniProtKB=P77211	P77211	cusC	PTHR30203:SF33	OUTER MEMBRANE CATION EFFLUX PROTEIN	CATION EFFLUX SYSTEM PROTEIN CUSC	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;membrane#GO:0016020		
ECOLI|EnsemblGenome=b0588|UniProtKB=P23878	P23878	fepC	PTHR42771:SF12	IRON(3+)-HYDROXAMATE IMPORT ATP-BINDING PROTEIN FHUC	FE(3+) DICITRATE TRANSPORT ATP-BINDING PROTEIN FECE-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;siderophore-iron transmembrane transporter activity#GO:0015343	siderophore-iron import into cell#GO:0033214;response to metal ion#GO:0010038;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;cellular response to stimulus#GO:0051716;metal ion transport#GO:0030001;homeostatic process#GO:0042592;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion homeostasis#GO:0050801;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;response to chemical#GO:0042221;iron coordination entity transport#GO:1901678;chemical homeostasis#GO:0048878;response to iron ion#GO:0010039;import into cell#GO:0098657;intracellular monoatomic ion homeostasis#GO:0006873;iron import into cell#GO:0033212;response to stimulus#GO:0050896;intracellular iron ion homeostasis#GO:0006879;cellular response to chemical stimulus#GO:0070887;iron ion transport#GO:0006826;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;cellular localization#GO:0051641;siderophore-dependent iron import pathway#GO:0180060;monoatomic ion transport#GO:0006811	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b2594|UniProtKB=P33643	P33643	rluD	PTHR21600:SF44	MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE	PSEUDOURIDINE SYNTHASE RSUA_RLUA-LIKE DOMAIN-CONTAINING PROTEIN	catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853	RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;rRNA modification#GO:0000154;pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254		RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b0175|UniProtKB=P0ABG1	P0ABG1	cdsA	PTHR46382:SF1	PHOSPHATIDATE CYTIDYLYLTRANSFERASE	PHOSPHATIDATE CYTIDYLYLTRANSFERASE	transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779	biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	metabolite interconversion enzyme#PC00262;transferase#PC00220	
ECOLI|EnsemblGenome=b0135|UniProtKB=P31058	P31058	yadC	PTHR33420:SF12	FIMBRIAL SUBUNIT ELFA-RELATED	FIMBRIN-LIKE PROTEIN FIMI-RELATED		cell-substrate adhesion#GO:0031589;cell adhesion#GO:0007155;cellular process#GO:0009987;single-species biofilm formation#GO:0044010	cellular anatomical structure#GO:0110165;cell projection#GO:0042995		
ECOLI|EnsemblGenome=b2322|UniProtKB=P77549	P77549	yfcJ	PTHR23517:SF1	RESISTANCE PROTEIN MDTM, PUTATIVE-RELATED-RELATED	SUBFAMILY NOT NAMED			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b1823|UniProtKB=P0A9Y6	P0A9Y6	cspC	PTHR11544:SF138	COLD SHOCK DOMAIN CONTAINING PROTEINS	COLD SHOCK PROTEIN CSPA-RELATED					
ECOLI|EnsemblGenome=b0934|UniProtKB=P75851	P75851	ssuC	PTHR30151:SF38	ALKANE SULFONATE ABC TRANSPORTER-RELATED, MEMBRANE SUBUNIT	ALIPHATIC SULFONATES TRANSPORT PERMEASE PROTEIN SSUC-RELATED			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b2513|UniProtKB=P76576	P76576	yfgM	PTHR38035:SF1	UPF0070 PROTEIN YFGM	ANCILLARY SECYEG TRANSLOCON SUBUNIT					
ECOLI|EnsemblGenome=b2074|UniProtKB=P76397	P76397	mdtA	PTHR30469:SF12	MULTIDRUG RESISTANCE PROTEIN MDTA	MULTIDRUG RESISTANCE PROTEIN MDTA	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;efflux transmembrane transporter activity#GO:0015562		transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;membrane#GO:0016020		
ECOLI|EnsemblGenome=b3463|UniProtKB=P0A9R7	P0A9R7	ftsE	PTHR24220:SF470	IMPORT ATP-BINDING PROTEIN	CELL DIVISION ATP-BINDING PROTEIN FTSE	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0789|UniProtKB=P0AA84	P0AA84	clsB	PTHR21248:SF23	CARDIOLIPIN SYNTHASE	CARDIOLIPIN SYNTHASE B	transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780	metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;phosphatidylglycerol metabolic process#GO:0046471;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;phosphatidylglycerol biosynthetic process#GO:0006655;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793	membrane#GO:0016020;cellular anatomical structure#GO:0110165	transferase#PC00220	
ECOLI|EnsemblGenome=b0320|UniProtKB=P77187	P77187	yahF	PTHR11117:SF24	SUCCINYL-COA LIGASE SUBUNIT ALPHA	OXAMATE CARBAMOYLTRANSFERASE SUBUNIT ALLF	ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874	metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;cellular process#GO:0009987	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;catalytic complex#GO:1902494	ligase#PC00142;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0634|UniProtKB=P0ABG7	P0ABG7	mrdB	PTHR30474:SF1	CELL CYCLE PROTEIN	PEPTIDOGLYCAN GLYCOSYLTRANSFERASE MRDB	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate derivative transmembrane transporter activity#GO:1901505	regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;cellular process#GO:0009987;cell division#GO:0051301;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of anatomical structure morphogenesis#GO:0022603;regulation of biological quality#GO:0065008	cell periphery#GO:0071944;membrane#GO:0016020;cell division site#GO:0032153;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b3309|UniProtKB=P60624	P60624	rplX	PTHR12903:SF13	MITOCHONDRIAL RIBOSOMAL PROTEIN L24	LARGE RIBOSOMAL SUBUNIT PROTEIN UL24C		biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152		ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b3493|UniProtKB=P0AFJ7	P0AFJ7	pitA	PTHR11101:SF65	PHOSPHATE TRANSPORTER	LOW-AFFINITY INORGANIC PHOSPHATE TRANSPORTER PITA-RELATED	active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;phosphate transmembrane transporter activity#GO:0005315;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	inorganic anion transport#GO:0015698;phosphate ion transport#GO:0006817;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b3131|UniProtKB=P0ACK2	P0ACK2	agaR	PTHR30363:SF61	HTH-TYPE TRANSCRIPTIONAL REGULATOR SRLR-RELATED	AGA OPERON TRANSCRIPTIONAL REPRESSOR-RELATED	nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355		DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b4012|UniProtKB=P09163	P09163	yjaB	PTHR43800:SF2	PEPTIDYL-LYSINE N-ACETYLTRANSFERASE YJAB	PEPTIDYL-LYSINE N-ACETYLTRANSFERASE YJAB	N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity#GO:0016746;protein N-acyltransferase activity#GO:0140186;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212			acetyltransferase#PC00038;transferase#PC00220	
ECOLI|EnsemblGenome=b0497|UniProtKB=P16919	P16919	rhsD	PTHR32305:SF18	FAMILY NOT NAMED	PROTEIN RHSA-RELATED					
ECOLI|EnsemblGenome=b3616|UniProtKB=P07913	P07913	tdh	PTHR43401:SF6	L-THREONINE 3-DEHYDROGENASE	L-THREONINE 3-DEHYDROGENASE	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491	oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2934|UniProtKB=P69824	P69824	cmtB	PTHR36203:SF4	ASCORBATE-SPECIFIC PTS SYSTEM EIIA COMPONENT	MANNITOL-SPECIFIC CRYPTIC PHOSPHOTRANSFERASE ENZYME IIA COMPONENT	phosphotransferase activity, alcohol group as acceptor#GO:0016773;carbohydrate transmembrane transporter activity#GO:0015144;protein-phosphocysteine-sugar phosphotransferase activity#GO:0090563;active transmembrane transporter activity#GO:0022804;catalytic activity#GO:0003824;transferase activity#GO:0016740;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transferase activity, transferring phosphorus-containing groups#GO:0016772	carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739;cellular process#GO:0009987;transmembrane transport#GO:0055085;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;transport#GO:0006810;carbohydrate transport#GO:0008643			
ECOLI|EnsemblGenome=b2077|UniProtKB=P36554	P36554	mdtD	PTHR23501:SF36	MAJOR FACILITATOR SUPERFAMILY	MULTIDRUG RESISTANCE PROTEIN MDTD-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b2012|UniProtKB=P33014	P33014	tsuB	PTHR33279:SF6	SULFUR CARRIER PROTEIN YEDF-RELATED	SULFUR CARRIER PROTEIN TSUB-RELATED				transfer/carrier protein#PC00219	
ECOLI|EnsemblGenome=b2467|UniProtKB=P37128	P37128	nudK	PTHR11839:SF38	UDP/ADP-SUGAR PYROPHOSPHATASE	GDP-MANNOSE PYROPHOSPHATASE	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787	phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086		metabolite interconversion enzyme#PC00262;pyrophosphatase#PC00196	
ECOLI|EnsemblGenome=b2672|UniProtKB=P0ADQ7	P0ADQ7	ygaM	PTHR35893:SF4	INNER MEMBRANE PROTEIN-RELATED	INNER MEMBRANE PROTEIN			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b3082|UniProtKB=P67701	P67701	higA	PTHR40455:SF1	ANTITOXIN HIGA	ANTITOXIN HIGA					
ECOLI|EnsemblGenome=b1119|UniProtKB=P75959	P75959	nagK	PTHR18964:SF162	ROK (REPRESSOR, ORF, KINASE) FAMILY	N-ACETYL-D-GLUCOSAMINE KINASE	carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301			winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b4083|UniProtKB=P32717	P32717	yjcS	PTHR43223:SF3	ALKYL/ARYL-SULFATASE	LINEAR PRIMARY-ALKYLSULFATASE	hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824	cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;sulfur compound metabolic process#GO:0006790;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to chemical#GO:0042221;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896	extracellular region#GO:0005576;periplasmic space#GO:0042597;cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288	hydrolase#PC00121	
ECOLI|EnsemblGenome=b2838|UniProtKB=P00861	P00861	lysA	PTHR43727:SF2	DIAMINOPIMELATE DECARBOXYLASE	GROUP IV DECARBOXYLASE	lyase activity#GO:0016829;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830	biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;aspartate family amino acid biosynthetic process#GO:0009067;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;L-lysine biosynthetic process#GO:0009085;amino acid biosynthetic process#GO:0008652		lyase#PC00144;decarboxylase#PC00089	Lysine biosynthesis#P02751>Diaminopimelate decarboxylase#P03007
ECOLI|EnsemblGenome=b3330|UniProtKB=P45760	P45760	gspI	PTHR38779:SF2	TYPE II SECRETION SYSTEM PROTEIN I-RELATED	TYPE II SECRETION SYSTEM PROTEIN I-RELATED		cellular process#GO:0009987;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;transport#GO:0006810;protein transmembrane transport#GO:0071806;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;protein secretion by the type II secretion system#GO:0015628;establishment of localization#GO:0051234;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;protein transport#GO:0015031;secretion by cell#GO:0032940;transmembrane transport#GO:0055085;secretion#GO:0046903;protein secretion#GO:0009306;localization#GO:0051179	protein-containing complex#GO:0032991;type II protein secretion system complex#GO:0015627		
ECOLI|EnsemblGenome=b0098|UniProtKB=P10408	P10408	secA	PTHR30612:SF0	SECA INNER MEMBRANE COMPONENT OF SEC PROTEIN SECRETION SYSTEM	PROTEIN TRANSLOCASE SUBUNIT SECA1, CHLOROPLASTIC	ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462	transport#GO:0006810;protein transmembrane transport#GO:0071806;protein transport#GO:0015031;intracellular protein localization#GO:0008104;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036	cell periphery#GO:0071944;membrane#GO:0016020;intracellular protein-containing complex#GO:0140535;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991	transporter#PC00227	
ECOLI|EnsemblGenome=b1468|UniProtKB=P19319	P19319	narZ	PTHR43105:SF15	RESPIRATORY NITRATE REDUCTASE	RESPIRATORY NITRATE REDUCTASE 2 ALPHA CHAIN			membrane#GO:0016020;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176;reductase#PC00198	
ECOLI|EnsemblGenome=b3845|UniProtKB=P21151	P21151	fadA	PTHR43853:SF11	3-KETOACYL-COA THIOLASE, PEROXISOMAL	3-KETOACYL-COA THIOLASE FADA	acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746	small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395		acetyltransferase#PC00038	
ECOLI|EnsemblGenome=b2354|UniProtKB=P77656	P77656	yfdK	PTHR34413:SF1	PROPHAGE TAIL FIBER ASSEMBLY PROTEIN HOMOLOG TFAE-RELATED-RELATED	CYTOPLASMIC PROTEIN				chaperone#PC00072	
ECOLI|EnsemblGenome=b1125|UniProtKB=P0AFK4	P0AFK4	potB	PTHR42929:SF1	INNER MEMBRANE ABC TRANSPORTER PERMEASE PROTEIN YDCU-RELATED-RELATED	INNER MEMBRANE ABC TRANSPORTER PERMEASE PROTEIN YDCU-RELATED	transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0194|UniProtKB=P16659	P16659	proS	PTHR42753:SF2	MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER	PROLINE--TRNA LIGASE	catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640	translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047	
ECOLI|EnsemblGenome=b4122|UniProtKB=P14407	P14407	fumB	PTHR30389:SF18	FUMARATE HYDRATASE-RELATED	FUMARATE HYDRATASE CLASS I, ANAEROBIC	hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824	generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	lyase#PC00144;hydratase#PC00120	
ECOLI|EnsemblGenome=b0698|UniProtKB=P03959	P03959	kdpA	PTHR30607:SF2	POTASSIUM-TRANSPORTING ATPASE A CHAIN	POTASSIUM-TRANSPORTING ATPASE POTASSIUM-BINDING SUBUNIT	primary active transmembrane transporter activity#GO:0015399;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657	transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220	cell periphery#GO:0071944;cation-transporting ATPase complex#GO:0090533;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ATPase dependent transmembrane transport complex#GO:0098533;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495	primary active transporter#PC00068;transporter#PC00227	
ECOLI|EnsemblGenome=b4199|UniProtKB=P0AF86	P0AF86	yjfY	PTHR34156:SF6	OUTER MEMBRANE PROTEIN-RELATED-RELATED	OUTER MEMBRANE PROTEIN		response to stress#GO:0006950;response to stimulus#GO:0050896			
ECOLI|EnsemblGenome=b2207|UniProtKB=P0A9I5	P0A9I5	napD	PTHR38603:SF1	CHAPERONE NAPD	CHAPERONE NAPD		regulation of transport#GO:0051049;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of establishment of protein localization#GO:0070201;negative regulation of protein transport#GO:0051224;biological regulation#GO:0065007;negative regulation of transport#GO:0051051;regulation of protein transport#GO:0051223;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	chaperone#PC00072	
ECOLI|EnsemblGenome=b1620|UniProtKB=P18811	P18811	malI	PTHR30146:SF148	LACI-RELATED TRANSCRIPTIONAL REPRESSOR	HTH-TYPE TRANSCRIPTIONAL REPRESSOR PURR-RELATED	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690	regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468		helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218;Lambda repressor-like transcription factor#PC00245	
ECOLI|EnsemblGenome=b1905|UniProtKB=P0A998	P0A998	ftnA	PTHR11431:SF127	FERRITIN	BACTERIAL NON-HEME FERRITIN	binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;catalytic activity#GO:0003824;ferrous iron binding#GO:0008198;iron ion binding#GO:0005506;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on metal ions#GO:0016722		cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	storage protein#PC00210	
ECOLI|EnsemblGenome=b2620|UniProtKB=P0A832	P0A832	smpB	PTHR30308:SF2	TMRNA-BINDING COMPONENT OF TRANS-TRANSLATION TAGGING COMPLEX	SSRA-BINDING PROTEIN	RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	translation factor#PC00223	
ECOLI|Gene_OrderedLocusName=JW0692|UniProtKB=P77779	P77779	ybfO	PTHR32305:SF18	FAMILY NOT NAMED	PROTEIN RHSA-RELATED					
ECOLI|EnsemblGenome=b2644|UniProtKB=P52140	P52140	yfjY	PTHR30471:SF3	DNA REPAIR PROTEIN RADC	UPF0758 PROTEIN YEES-RELATED				DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b0610|UniProtKB=P0AFW4	P0AFW4	rnk	PTHR30437:SF5	TRANSCRIPTION ELONGATION FACTOR GREA	REGULATOR OF NUCLEOSIDE DIPHOSPHATE KINASE		gene expression#GO:0010467;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription elongation#GO:0006354;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187			
ECOLI|EnsemblGenome=b1066|UniProtKB=P0A948	P0A948	rimJ	PTHR43792:SF8	GNAT FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00765)-RELATED-RELATED	[RIBOSOMAL PROTEIN US5]-ALANINE N-ACETYLTRANSFERASE	acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747		cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0343|UniProtKB=P02920	P02920	lacY	PTHR23522:SF10	BLL5896 PROTEIN	3-PHENYLPROPIONIC ACID TRANSPORTER-RELATED			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b3338|UniProtKB=P13656	P13656	chiA	PTHR42976:SF1	BIFUNCTIONAL CHITINASE/LYSOZYME-RELATED	GH18 DOMAIN-CONTAINING PROTEIN-RELATED	hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568				
ECOLI|EnsemblGenome=b2164|UniProtKB=P33024	P33024	psuT	PTHR10590:SF4	SODIUM/NUCLEOSIDE COTRANSPORTER	NUCLEOSIDE PERMEASE NUPX-RELATED	secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;nucleoside transmembrane transporter activity#GO:0005337;symporter activity#GO:0015293;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932	nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b2210|UniProtKB=P33940	P33940	mqo	PTHR13847:SF277	SARCOSINE DEHYDROGENASE-RELATED	MALATE:QUINONE OXIDOREDUCTASE			cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b1668|UniProtKB=P77148	P77148	ydhS	PTHR40254:SF1	BLR0577 PROTEIN	FAD-DEPENDENT URATE HYDROXYLASE HPYO_ASP MONOOXYGENASE CREE-LIKE FAD_NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN					
ECOLI|EnsemblGenome=b3659|UniProtKB=P31436	P31436	setC	PTHR23535:SF2	SUGAR EFFLUX TRANSPORTER A-RELATED	SUGAR EFFLUX TRANSPORTER A-RELATED	monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;solute:proton symporter activity#GO:0015295;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078	cellular response to chemical stress#GO:0062197;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;carbohydrate transport#GO:0008643;cellular response to stress#GO:0033554;transport#GO:0006810;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;response to chemical#GO:0042221;carbohydrate transmembrane transport#GO:0034219;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b0908|UniProtKB=P0A6D3	P0A6D3	aroA	PTHR21090:SF5	AROM/DEHYDROQUINATE SYNTHASE	PENTAFUNCTIONAL AROM POLYPEPTIDE	transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740	small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	transferase#PC00220;metabolite interconversion enzyme#PC00262	Chorismate biosynthesis#P02734>3-Dehydroquinate synthase#P02872;Chorismate biosynthesis#P02734>3-Phosphoshikimate-1-carboxyvinyl transferase#P02870
ECOLI|EnsemblGenome=b2962|UniProtKB=P0A8P3	P0A8P3	yggX	PTHR36965:SF1	FE(2+)-TRAFFICKING PROTEIN-RELATED	FE(2+)-TRAFFICKING PROTEIN-RELATED		cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b4024|UniProtKB=P08660	P08660	lysC	PTHR21499:SF59	ASPARTATE KINASE	ASPARTOKINASE	catalytic activity#GO:0003824;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772	cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	amino acid kinase#PC00045;kinase#PC00137	Lysine biosynthesis#P02751>Aspartokinase#P03009;Threonine biosynthesis#P02781>Aspartate kinase#P03189
ECOLI|EnsemblGenome=b0260|UniProtKB=Q47689	Q47689	mmuP	PTHR43341:SF5	AMINO ACID PERMEASE	S-METHYLMETHIONINE PERMEASE-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171	cellular process#GO:0009987;amino acid transport#GO:0006865;transport#GO:0006810;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085	membrane#GO:0016020;cellular anatomical structure#GO:0110165	amino acid transporter#PC00046;transporter#PC00227	
ECOLI|EnsemblGenome=b4238|UniProtKB=P28903	P28903	nrdD	PTHR21075:SF0	ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE	ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654	catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;reductase#PC00198	De novo purine biosynthesis#P02738>ATP reductase#P02893;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>Ribonucleoside triphosphate Reductase#P02917;De novo purine biosynthesis#P02738>GTP reductase#P02897
ECOLI|EnsemblGenome=b0345|UniProtKB=P03023	P03023	lacI	PTHR30146:SF138	LACI-RELATED TRANSCRIPTIONAL REPRESSOR	LACTOSE OPERON REPRESSOR	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789		DNA-binding transcription factor#PC00218;Lambda repressor-like transcription factor#PC00245;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b2821|UniProtKB=P05458	P05458	ptrA	PTHR43690:SF18	NARDILYSIN	PROTEASE 3	catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222	macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238		metalloprotease#PC00153;protein modifying enzyme#PC00260;protease#PC00190	
ECOLI|EnsemblGenome=b2095|UniProtKB=P0C8J8	P0C8J8	gatZ	PTHR32502:SF12	N-ACETYLGALACTOSAMINE PERMEASE II COMPONENT-RELATED	D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE SUBUNIT GATZ	enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234	transport#GO:0006810;carbohydrate transport#GO:0008643;transmembrane transport#GO:0055085;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b0267|UniProtKB=P37007	P37007	yagA	PTHR42648:SF15	TRANSPOSASE, PUTATIVE-RELATED	NONCOMPOSITE TRANSPOSON TRANSPOSASE				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b3453|UniProtKB=P0AG80	P0AG80	ugpB	PTHR43649:SF31	ARABINOSE-BINDING PROTEIN-RELATED	SN-GLYCEROL-3-PHOSPHATE-BINDING PERIPLASMIC PROTEIN UGPB	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	carbohydrate derivative transport#GO:1901264;transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;organophosphate ester transport#GO:0015748;localization#GO:0051179	membrane#GO:0016020;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2601|UniProtKB=P00888	P00888	aroF	PTHR21225:SF10	PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE  DAHP SYNTHETASE	PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, TYR-SENSITIVE	transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765	small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;aromatic amino acid biosynthetic process#GO:0009073;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	aldolase#PC00044;lyase#PC00144	Chorismate biosynthesis#P02734>2-Deoxy-7-phosphoheptulonate synthase#P02871
ECOLI|EnsemblGenome=b1734|UniProtKB=P17411	P17411	chbF	PTHR32092:SF15	6-PHOSPHO-BETA-GLUCOSIDASE-RELATED	6-PHOSPHO-BETA-GLUCOSIDASE	hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;glucosidase activity#GO:0015926;beta-glucosidase activity#GO:0008422;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798		cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;glucosidase#PC00108	
ECOLI|EnsemblGenome=b0886|UniProtKB=P23886	P23886	cydC	PTHR24222:SF30	ABC TRANSPORTER B FAMILY	GLUTATHIONE_L-CYSTEINE TRANSPORT SYSTEM ATP-BINDING_PERMEASE PROTEIN CYDC	primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626	carboxylic acid transmembrane transport#GO:1905039;export from cell#GO:0140352;nitrogen compound transport#GO:0071705;L-alpha-amino acid transmembrane transport#GO:1902475;L-amino acid transport#GO:0015807;cellular process#GO:0009987;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227	
ECOLI|EnsemblGenome=b0051|UniProtKB=P06992	P06992	rsmA	PTHR11727:SF33	DIMETHYLADENOSINE TRANSFERASE	RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE A	N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173	RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA modification#GO:0000154;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA methylation#GO:0001510;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	RNA metabolism protein#PC00031;RNA methyltransferase#PC00033	
ECOLI|EnsemblGenome=b0171|UniProtKB=P0A7E9	P0A7E9	pyrH	PTHR42833:SF8	URIDYLATE KINASE	URIDYLATE KINASE	kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, phosphate group as acceptor#GO:0016776	nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;ribonucleoside diphosphate metabolic process#GO:0009185;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;nucleoside diphosphate metabolic process#GO:0009132;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	nucleotide kinase#PC00172;kinase#PC00137	
ECOLI|EnsemblGenome=b0806|UniProtKB=P0AAX6	P0AAX6	mcbA	PTHR34156:SF1	OUTER MEMBRANE PROTEIN-RELATED-RELATED	EXPORTED PROTEIN		response to stress#GO:0006950;response to stimulus#GO:0050896			
ECOLI|EnsemblGenome=b3321|UniProtKB=P0A7R5	P0A7R5	rpsJ	PTHR11700:SF51	30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER	SMALL RIBOSOMAL SUBUNIT PROTEIN US10	structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198		ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232	ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b2473|UniProtKB=P76561	P76561	ypfH	PTHR10655:SF17	LYSOPHOSPHOLIPASE-RELATED	ESTERASE YPFH	hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824			lipase#PC00143;phospholipase#PC00186	
ECOLI|EnsemblGenome=b1249|UniProtKB=P0A6H8	P0A6H8	clsA	PTHR21248:SF24	CARDIOLIPIN SYNTHASE	CARDIOLIPIN SYNTHASE A	transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772	primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phosphatidylglycerol biosynthetic process#GO:0006655;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;phosphatidylglycerol metabolic process#GO:0046471;glycerolipid metabolic process#GO:0046486;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152	cellular anatomical structure#GO:0110165;membrane#GO:0016020	transferase#PC00220	
ECOLI|EnsemblGenome=b2898|UniProtKB=P0ADE8	P0ADE8	ygfZ	PTHR22602:SF1	IRON-SULFUR CLUSTER ASSEMBLY FACTOR CAF17/IBA57, MITOCHONDRIAL	TRNA-MODIFYING PROTEIN YGFZ					
ECOLI|EnsemblGenome=b1919|UniProtKB=P76316	P76316	dcyD	PTHR43780:SF2	1-AMINOCYCLOPROPANE-1-CARBOXYLATE DEAMINASE-RELATED	BIFUNCTIONAL D-CYSTEINE DESULFHYDRASE_1-AMINOCYCLOPROPANE-1-CARBOXYLATE DEAMINASE, MITOCHONDRIAL	carbon-sulfur lyase activity#GO:0016846;lyase activity#GO:0016829;catalytic activity#GO:0003824		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	deaminase#PC00088;hydrolase#PC00121	
ECOLI|EnsemblGenome=b3897|UniProtKB=P32152	P32152	frvR	PTHR30185:SF14	CRYPTIC BETA-GLUCOSIDE BGL OPERON ANTITERMINATOR	STATIONARY PHASE-INDUCIBLE PROTEIN CSIE-RELATED					
ECOLI|EnsemblGenome=b2286|UniProtKB=P33599	P33599	nuoC	PTHR11993:SF45	NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT	NADH-QUINONE OXIDOREDUCTASE SUBUNIT C_D	electron transfer activity#GO:0009055;oxidoreductase activity, acting on NAD(P)H#GO:0016651;monoatomic cation transmembrane transporter activity#GO:0008324;NADH dehydrogenase activity#GO:0003954;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;metabolic process#GO:0008152;electron transport chain#GO:0022900	respiratory chain complex#GO:0098803;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351	metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1871|UniProtKB=P76291	P76291	cmoB	PTHR43464:SF19	METHYLTRANSFERASE	JUVENILE HORMONE ACID O-METHYLTRANSFERASE	methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824			methyltransferase#PC00155;transferase#PC00220	
ECOLI|EnsemblGenome=b3287|UniProtKB=P0A6K3	P0A6K3	def	PTHR10458:SF21	PEPTIDE DEFORMYLASE	PEPTIDE DEFORMYLASE				hydrolase#PC00121	
ECOLI|EnsemblGenome=b0305|UniProtKB=P77379	P77379	rclR	PTHR43280:SF11	ARAC-FAMILY TRANSCRIPTIONAL REGULATOR	RCS-SPECIFIC HTH-TYPE TRANSCRIPTIONAL ACTIVATOR RCLR	transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252		DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b3934|UniProtKB=P0ACN7	P0ACN7	cytR	PTHR30146:SF151	LACI-RELATED TRANSCRIPTIONAL REPRESSOR	HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110	biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355		helix-turn-helix transcription factor#PC00116;Lambda repressor-like transcription factor#PC00245;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b3259|UniProtKB=P0A8T1	P0A8T1	prmA	PTHR43648:SF4	ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT LYSINE METHYLTRANSFERASE	RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE	catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;lysine N-methyltransferase activity#GO:0016278;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	methyltransferase#PC00155	
ECOLI|EnsemblGenome=b3014|UniProtKB=P65298	P65298	yqhH	PTHR38763:SF1	MAJOR OUTER MEMBRANE PROLIPOPROTEIN LPP	MAJOR OUTER MEMBRANE LIPOPROTEIN LPP					
ECOLI|EnsemblGenome=b0227|UniProtKB=Q47151	Q47151	yafL	PTHR47053:SF1	MUREIN DD-ENDOPEPTIDASE MEPH-RELATED	MUREIN DD-ENDOPEPTIDASE MEPH-RELATED	endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824	carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;peptidoglycan metabolic process#GO:0000270;glycosaminoglycan metabolic process#GO:0030203;macromolecule metabolic process#GO:0043170			
ECOLI|EnsemblGenome=b0960|UniProtKB=P75870	P75870	yccS	PTHR30509:SF8	P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT-RELATED	INNER MEMBRANE PROTEIN YCCS			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b2388|UniProtKB=P0A6V8	P0A6V8	glk	PTHR47690:SF1	GLUCOKINASE	GLUCOKINASE	transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773		cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	transferase#PC00220;kinase#PC00137	
ECOLI|EnsemblGenome=b4297|UniProtKB=P39358	P39358	yjhG	PTHR43661:SF3	D-XYLONATE DEHYDRATASE	D-XYLONATE DEHYDRATASE YAGF-RELATED	catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836		cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	dehydratase#PC00091	Valine biosynthesis#P02785>Dihydroxy isovalerate dehydratase#P03218;Isoleucine biosynthesis#P02748>Dihydroxyacid dehydratase#P02998
ECOLI|EnsemblGenome=b0166|UniProtKB=P0A9D8	P0A9D8	dapD	PTHR19136:SF52	MOLYBDENUM COFACTOR GUANYLYLTRANSFERASE	2,3,4,5-TETRAHYDROPYRIDINE-2,6-DICARBOXYLATE N-SUCCINYLTRANSFERASE	transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;L-lysine biosynthetic process#GO:0009085;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;aspartate family amino acid biosynthetic process#GO:0009067;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520		transferase#PC00220	
ECOLI|EnsemblGenome=b1376|UniProtKB=P37903	P37903	uspF	PTHR46268:SF18	STRESS RESPONSE PROTEIN NHAX	UNIVERSAL STRESS PROTEIN F					
ECOLI|EnsemblGenome=b1533|UniProtKB=P31125	P31125	eamA	PTHR32322:SF9	INNER MEMBRANE TRANSPORTER	AMINO-ACID METABOLITE EFFLUX PUMP-RELATED	efflux transmembrane transporter activity#GO:0015562;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;export from cell#GO:0140352;carboxylic acid transmembrane transport#GO:1905039;L-amino acid transport#GO:0015807;L-alpha-amino acid transmembrane transport#GO:1902475;nitrogen compound transport#GO:0071705;cellular process#GO:0009987		transporter#PC00227	
ECOLI|EnsemblGenome=b4207|UniProtKB=P0A9L3	P0A9L3	fklB	PTHR43811:SF23	FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA	FKBP-TYPE 22 KDA PEPTIDYL-PROLYL CIS-TRANS ISOMERASE	catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859			chaperone#PC00072	
ECOLI|EnsemblGenome=b4035|UniProtKB=P68187	P68187	malK	PTHR43875:SF3	MALTODEXTRIN IMPORT ATP-BINDING PROTEIN MSMX	MALTOSE_MALTODEXTRIN IMPORT ATP-BINDING PROTEIN MALK	primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;carbohydrate transmembrane transporter activity#GO:0015144;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657	localization#GO:0051179;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;carbohydrate transport#GO:0008643;transport#GO:0006810	ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ATP-binding cassette (ABC) transporter complex#GO:0043190;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020	primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b1709|UniProtKB=P06611	P06611	btuD	PTHR42734:SF18	METAL TRANSPORT SYSTEM ATP-BINDING PROTEIN TM_0124-RELATED	VITAMIN B12 IMPORT ATP-BINDING PROTEIN BTUD	active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657		cell periphery#GO:0071944;ATP-binding cassette (ABC) transporter complex#GO:0043190;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ATPase dependent transmembrane transport complex#GO:0098533;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495	transporter#PC00227;primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0660|UniProtKB=P0A9K3	P0A9K3	ybeZ	PTHR30473:SF1	PROTEIN PHOH	PHOH-LIKE PROTEIN	anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ATP binding#GO:0005524;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166		cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b2400|UniProtKB=P04805	P04805	gltX	PTHR43311:SF3	GLUTAMATE--TRNA LIGASE	GLUTAMATE--TRNA LIGASE	catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098	protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039		aminoacyl-tRNA synthetase#PC00047	Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977
ECOLI|EnsemblGenome=b4407|UniProtKB=O32583	O32583	thiS	PTHR34472:SF1	SULFUR CARRIER PROTEIN THIS	SULFUR CARRIER PROTEIN THIS	molecular carrier activity#GO:0140104	cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;biosynthetic process#GO:0009058	transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991	transfer/carrier protein#PC00219	
ECOLI|EnsemblGenome=b3206|UniProtKB=P0A9N0	P0A9N0	ptsO	PTHR33705:SF2	PHOSPHOCARRIER PROTEIN HPR	PHOSPHOCARRIER PROTEIN NPR		import across plasma membrane#GO:0098739;carbohydrate transmembrane transport#GO:0034219;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;import into cell#GO:0098657;establishment of localization#GO:0051234;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;carbohydrate transport#GO:0008643;transport#GO:0006810		transfer/carrier protein#PC00219	
ECOLI|EnsemblGenome=b4136|UniProtKB=P36655	P36655	dsbD	PTHR32234:SF0	THIOL:DISULFIDE INTERCHANGE PROTEIN DSBD	THIOL:DISULFIDE INTERCHANGE PROTEIN DSBD	protein-disulfide reductase activity#GO:0015035;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824	cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592		chaperone#PC00072	
ECOLI|EnsemblGenome=b2497|UniProtKB=P0AGM7	P0AGM7	uraA	PTHR11119:SF127	XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER	XANTHINE_URACIL PERMEASE FAMILY PROTEIN	monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;nucleobase transmembrane transporter activity#GO:0015205;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	nucleobase transport#GO:0015851;transport#GO:0006810;pyrimidine nucleobase transport#GO:0015855;transmembrane transport#GO:0055085;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;import across plasma membrane#GO:0098739	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b0613|UniProtKB=P77231	P77231	citG	PTHR30201:SF2	TRIPHOSPHORIBOSYL-DEPHOSPHO-COA SYNTHASE	2-(5''-TRIPHOSPHORIBOSYL)-3'-DEPHOSPHOCOENZYME-A SYNTHASE	phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740	metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;biosynthetic process#GO:0009058		transferase#PC00220	
ECOLI|EnsemblGenome=b0988|UniProtKB=P57998	P57998	insB4	PTHR33293:SF1	INSERTION ELEMENT IS1 1 PROTEIN INSB-RELATED	INSERTION ELEMENT IS1 1 PROTEIN INSB-RELATED					
ECOLI|EnsemblGenome=b2011|UniProtKB=P04995	P04995	sbcB	PTHR11046:SF11	OLIGORIBONUCLEASE, MITOCHONDRIAL	EXODEOXYRIBONUCLEASE I				RNA metabolism protein#PC00031;endoribonuclease#PC00094	
ECOLI|EnsemblGenome=b3882|UniProtKB=P0A9V8	P0A9V8	yihU	PTHR22981:SF7	3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED	3-SULFOLACTALDEHYDE REDUCTASE	catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614			dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b4466|UniProtKB=P0CK95	P0CK95	yghJ	PTHR15730:SF5	EXPERIMENTAL AUTOIMMUNE PROSTATITIS ANTIGEN 2-RELATED	LIPOPROTEIN ACFD HOMOLOG-RELATED	transmembrane transporter binding#GO:0044325;binding#GO:0005488;protein binding#GO:0005515		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b3308|UniProtKB=P62399	P62399	rplE	PTHR11994:SF4	60S RIBOSOMAL PROTEIN L11-RELATED	LARGE RIBOSOMAL SUBUNIT PROTEIN UL5	RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676	macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538	large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391	translational protein#PC00263;ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b1629|UniProtKB=P77611	P77611	rsxC	PTHR43034:SF2	ION-TRANSLOCATING OXIDOREDUCTASE COMPLEX SUBUNIT C	ION-TRANSLOCATING OXIDOREDUCTASE COMPLEX SUBUNIT C	catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491				
ECOLI|EnsemblGenome=b4187|UniProtKB=P33224	P33224	aidB	PTHR42707:SF3	ACYL-COA DEHYDROGENASE	ACYL-COA DEHYDROGENASE AIDB-RELATED	oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824			dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3597|UniProtKB=P0AFV0	P0AFV0	yibH	PTHR30386:SF18	MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP	INNER MEMBRANE PROTEIN YIAV-RELATED			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b2921|UniProtKB=P52044	P52044	ygfI	PTHR30579:SF0	TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL ACTIVATOR ALLS	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007		DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b0684|UniProtKB=P61949	P61949	fldA	PTHR42809:SF1	FLAVODOXIN 2	FLAVODOXIN 1					
ECOLI|EnsemblGenome=b1649|UniProtKB=P67430	P67430	nemR	PTHR47506:SF6	TRANSCRIPTIONAL REGULATORY PROTEIN	HTH-TYPE TRANSCRIPTIONAL REPRESSOR NEMR		negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523		Tet repressor-like transcription factor#PC00266	
ECOLI|EnsemblGenome=b3430|UniProtKB=P0A6V1	P0A6V1	glgC	PTHR43523:SF2	GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE-RELATED	GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE	adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740	macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042;carbohydrate biosynthetic process#GO:0016051;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;polysaccharide metabolic process#GO:0005976;polysaccharide biosynthetic process#GO:0000271;metabolic process#GO:0008152;glucan biosynthetic process#GO:0009250;macromolecule metabolic process#GO:0043170	transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535	nucleotidyltransferase#PC00174;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1219|UniProtKB=P0AB52	P0AB52	ychN	PTHR34874:SF1	PROTEIN YCHN	PROTEIN YCHN			cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b2748|UniProtKB=P0A6S5	P0A6S5	ftsB	PTHR37485:SF1	CELL DIVISION PROTEIN FTSB	CELL DIVISION PROTEIN FTSB		cellular process#GO:0009987;cell division#GO:0051301;cell cycle process#GO:0022402;cell cycle#GO:0007049;reproductive process#GO:0022414;reproductive process in single-celled organism#GO:0022413;cytokinesis#GO:0000910;FtsZ-dependent cytokinesis#GO:0043093	cell septum#GO:0030428;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1067|UniProtKB=P29217	P29217	yceH	PTHR38768:SF1	UPF0502 PROTEIN YCEH	UPF0502 PROTEIN YCEH					
ECOLI|EnsemblGenome=b0089|UniProtKB=P0ABG4	P0ABG4	ftsW	PTHR30474:SF2	CELL CYCLE PROTEIN	PEPTIDOGLYCAN GLYCOSYLTRANSFERASE FTSW-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate derivative transmembrane transporter activity#GO:1901505	regulation of anatomical structure morphogenesis#GO:0022603;regulation of biological quality#GO:0065008;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of biological process#GO:0050789;cellular process#GO:0009987;cell division#GO:0051301;regulation of cell shape#GO:0008360	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell division site#GO:0032153		
ECOLI|EnsemblGenome=b1727|UniProtKB=P77247	P77247	hxpB	PTHR46193:SF24	6-PHOSPHOGLUCONATE PHOSPHATASE	HEXITOL PHOSPHATASE B	sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578			metabolite interconversion enzyme#PC00262;phosphatase#PC00181	
ECOLI|EnsemblGenome=b0238|UniProtKB=P0A9M5	P0A9M5	gpt	PTHR39563:SF1	XANTHINE PHOSPHORIBOSYLTRANSFERASE	XANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757	primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;IMP metabolic process#GO:0046040;IMP biosynthetic process#GO:0006188;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside phosphate biosynthetic process#GO:1901293;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	transferase#PC00220	
ECOLI|EnsemblGenome=b1598|UniProtKB=P76176	P76176	ydgD	PTHR15462:SF8	SERINE PROTEASE	SERINE PROTEASE				serine protease#PC00203	
ECOLI|EnsemblGenome=b1412|UniProtKB=P41407	P41407	azoR	PTHR43741:SF2	FMN-DEPENDENT NADH-AZOREDUCTASE 1	FMN-DEPENDENT NADH:QUINONE OXIDOREDUCTASE	catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491	response to stress#GO:0006950;response to stimulus#GO:0050896;response to oxidative stress#GO:0006979		oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;reductase#PC00198	
ECOLI|EnsemblGenome=b1483|UniProtKB=P77622	P77622	ddpF	PTHR43776:SF16	TRANSPORT ATP-BINDING PROTEIN	D,D-DIPEPTIDE TRANSPORT ATP-BINDING PROTEIN DDPF-RELATED	carbohydrate derivative transmembrane transporter activity#GO:1901505;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b1680|UniProtKB=P77444	P77444	sufS	PTHR43586:SF25	CYSTEINE DESULFURASE	CYSTEINE DESULFURASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782			lyase#PC00144	
ECOLI|EnsemblGenome=b2195|UniProtKB=P0AA86	P0AA86	dsbE	PTHR42852:SF19	THIOL:DISULFIDE INTERCHANGE PROTEIN DSBE	THIOL:DISULFIDE INTERCHANGE PROTEIN DSBE	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085		oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0797|UniProtKB=P25888	P25888	rhlE	PTHR47959:SF13	ATP-DEPENDENT RNA HELICASE RHLE-RELATED	ATP-DEPENDENT RNA HELICASE RHLE	ATP-dependent activity#GO:0140657;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	RNA helicase#PC00032	
ECOLI|EnsemblGenome=b3070|UniProtKB=Q46871	Q46871	yqjH	PTHR30157:SF0	FERRIC REDUCTASE, NADPH-DEPENDENT	NADPH-DEPENDENT FERRIC-CHELATE REDUCTASE	ferric-chelate reductase activity#GO:0000293;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;catalytic activity#GO:0003824;oxidoreductase activity, acting on metal ions#GO:0016722;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363	cellular process#GO:0009987;establishment of localization in cell#GO:0051649;response to stress#GO:0006950;monoatomic ion homeostasis#GO:0050801;response to nutrient levels#GO:0031667;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;cellular response to nutrient levels#GO:0031669;iron coordination entity transport#GO:1901678;cellular response to starvation#GO:0009267;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;cellular response to stimulus#GO:0051716;intracellular monoatomic ion homeostasis#GO:0006873;response to starvation#GO:0042594;iron import into cell#GO:0033212;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular iron ion homeostasis#GO:0006879;response to stimulus#GO:0050896;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;iron ion transport#GO:0006826;cellular response to stress#GO:0033554;monoatomic ion transport#GO:0006811;cellular localization#GO:0051641;localization#GO:0051179;monoatomic cation transport#GO:0006812		oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1211|UniProtKB=P0A7I0	P0A7I0	prfA	PTHR43804:SF7	LD18447P	LD18447P				translation release factor#PC00225;translation factor#PC00223;translational protein#PC00263	
ECOLI|EnsemblGenome=b3919|UniProtKB=P0A858	P0A858	tpiA	PTHR21139:SF42	TRIOSEPHOSPHATE ISOMERASE	TRIOSEPHOSPHATE ISOMERASE	catalytic activity#GO:0003824;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853	monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;ADP metabolic process#GO:0046031;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate catabolic process#GO:1901292;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;carbohydrate biosynthetic process#GO:0016051;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;ADP catabolic process#GO:0046032;pyruvate metabolic process#GO:0006090;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;monocarboxylic acid metabolic process#GO:0032787;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;energy derivation by oxidation of organic compounds#GO:0015980;small molecule biosynthetic process#GO:0044283;nucleotide catabolic process#GO:0009166;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;nucleoside diphosphate catabolic process#GO:0009134;hexose biosynthetic process#GO:0019319;purine ribonucleotide catabolic process#GO:0009154;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;purine nucleotide catabolic process#GO:0006195;aldehyde metabolic process#GO:0006081;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;gluconeogenesis#GO:0006094;carbohydrate derivative biosynthetic process#GO:1901137;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;ribonucleoside diphosphate metabolic process#GO:0009185;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;glyceraldehyde-3-phosphate metabolic process#GO:0019682;oxoacid metabolic process#GO:0043436	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	isomerase#PC00135;metabolite interconversion enzyme#PC00262	Glycolysis#P00024>Triosephosphate isomerase#P00673
ECOLI|EnsemblGenome=b3591|UniProtKB=P0A821	P0A821	selA	PTHR32328:SF0	L-SERYL-TRNA(SEC) SELENIUM TRANSFERASE	L-SERYL-TRNA(SEC) SELENIUM TRANSFERASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101	RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;oxoacid metabolic process#GO:0043436;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;small molecule metabolic process#GO:0044281;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;modified amino acid metabolic process#GO:0006575;nucleic acid metabolic process#GO:0090304;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;proteinogenic amino acid biosynthetic process#GO:0170038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;amino acid biosynthetic process#GO:0008652;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule biosynthetic process#GO:0044283;gene expression#GO:0010467;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;amino acid metabolic process#GO:0006520;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	translational protein#PC00263	
ECOLI|EnsemblGenome=b3397|UniProtKB=P45799	P45799	nudE	PTHR11839:SF12	UDP/ADP-SUGAR PYROPHOSPHATASE	ADP COMPOUNDS HYDROLASE NUDE		ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;pyrophosphatase#PC00196	
ECOLI|EnsemblGenome=b1969|UniProtKB=P76340	P76340	hprR	PTHR48111:SF41	REGULATOR OF RPOS	TRANSCRIPTIONAL REGULATORY PROTEIN CUSR-RELATED	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090	cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b3525|UniProtKB=P37646	P37646	pdeH	PTHR33121:SF78	CYCLIC DI-GMP PHOSPHODIESTERASE PDEF	CYCLIC DI-GMP PHOSPHODIESTERASE PDEH	hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081	biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185	
ECOLI|EnsemblGenome=b3580|UniProtKB=P37677	P37677	lyx	PTHR43095:SF3	SUGAR KINASE	L-XYLULOSE_3-KETO-L-GULONATE KINASE	transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740			carbohydrate kinase#PC00065	Ascorbate degradation#P02729>L-xylulose kinase#P02849
ECOLI|EnsemblGenome=b3705|UniProtKB=P25714	P25714	yidC	PTHR12428:SF65	OXA1	MEMBRANE PROTEIN INSERTASE YIDC	molecular carrier activity#GO:0140104;membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597	localization within membrane#GO:0051668;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;cellular component organization#GO:0016043;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024		transporter#PC00227	
ECOLI|EnsemblGenome=b0803|UniProtKB=P41039	P41039	ybiI	PTHR38777:SF1	FELS-2 PROPHAGE PROTEIN	ZINC FINGER DKSA_TRAR C4-TYPE DOMAIN-CONTAINING PROTEIN		positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of cellular process#GO:0050794			
ECOLI|EnsemblGenome=b2715|UniProtKB=P24241	P24241	ascF	PTHR30175:SF1	PHOSPHOTRANSFERASE SYSTEM TRANSPORT PROTEIN	PTS SYSTEM N-ACETYLMURAMIC ACID-SPECIFIC EIIBC COMPONENT-RELATED				secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b4249|UniProtKB=P39333	P39333	bdcA	PTHR43943:SF2	DEHYDROGENASE/REDUCTASE (SDR FAMILY) MEMBER 4	SHORT-CHAIN DEHYDROGENASE_REDUCTASE SDRA				metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b1479|UniProtKB=P26616	P26616	maeA	PTHR23406:SF103	MALIC ENZYME-RELATED	NAD-DEPENDENT MALIC ENZYME	oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b4386|UniProtKB=P32099	P32099	lplA	PTHR12561:SF6	LIPOATE-PROTEIN LIGASE	LIPOATE-PROTEIN LIGASE A	ligase activity, forming carbon-nitrogen bonds#GO:0016879;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746		cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	protein modifying enzyme#PC00260	
ECOLI|EnsemblGenome=b2489|UniProtKB=P77668	P77668	hyfI	PTHR42989:SF1	HYDROGENASE-4 COMPONENT I	FORMATE HYDROGENLYASE SUBUNIT 7-RELATED		anaerobic electron transport chain#GO:0019645;anaerobic respiration#GO:0009061;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;monocarboxylic acid metabolic process#GO:0032787;electron transport chain#GO:0022900;carboxylic acid metabolic process#GO:0019752;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152	oxidoreductase complex#GO:1990204;catalytic complex#GO:1902494;protein-containing complex#GO:0032991	oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0159|UniProtKB=P0AF12	P0AF12	mtnN	PTHR46832:SF1	5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE	5'-METHYLTHIOADENOSINE_S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE	catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b1652|UniProtKB=P30014	P30014	rnt	PTHR30231:SF2	DNA POLYMERASE III SUBUNIT EPSILON	RIBONUCLEASE T	hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;nuclease activity#GO:0004518;hydrolase activity#GO:0016787	macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;cellular process#GO:0009987	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	DNA metabolism protein#PC00009	
ECOLI|Gene_OrderedLocusName=b2139|UniProtKB=P33369	P33369	mdtQ	PTHR30203:SF20	OUTER MEMBRANE CATION EFFLUX PROTEIN	MULTIDRUG RESISTANCE OUTER MEMBRANE PROTEIN MDTP-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987	membrane#GO:0016020;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2707|UniProtKB=P15082	P15082	srlR	PTHR30363:SF62	HTH-TYPE TRANSCRIPTIONAL REGULATOR SRLR-RELATED	GLUCITOL OPERON REPRESSOR	DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222		DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b3361|UniProtKB=P20605	P20605	fic	PTHR39560:SF1	PROTEIN ADENYLYLTRANSFERASE FIC-RELATED	PROTEIN ADENYLYLTRANSFERASE FIC-RELATED	catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566	metabolic process#GO:0008152;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538		protein modifying enzyme#PC00260	
ECOLI|Gene_OrderedLocusName=JW3865|UniProtKB=P32176	P32176	fdoG	PTHR43598:SF1	TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE 2 SUBUNIT B	FORMATE DEHYDROGENASE-O MAJOR SUBUNIT	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;anaerobic respiration#GO:0009061;small molecule metabolic process#GO:0044281;generation of precursor metabolites and energy#GO:0006091;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980	catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991	dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b3603|UniProtKB=P33231	P33231	lldP	PTHR30003:SF0	L-LACTATE PERMEASE	GLYCOLATE PERMEASE GLCA-RELATED	monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:proton symporter activity#GO:0015295;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b3751|UniProtKB=P02925	P02925	rbsB	PTHR46847:SF1	D-ALLOSE-BINDING PERIPLASMIC PROTEIN-RELATED	D-ALLOSE-BINDING PERIPLASMIC PROTEIN-RELATED	small molecule binding#GO:0036094;binding#GO:0005488;carbohydrate binding#GO:0030246;monosaccharide binding#GO:0048029	transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179	periplasmic space#GO:0042597;extracellular region#GO:0005576;cell envelope#GO:0030313;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0583|UniProtKB=P19925	P19925	entD	PTHR38096:SF1	ENTEROBACTIN SYNTHASE COMPONENT D	ENTEROBACTIN SYNTHASE COMPONENT D	phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740	metabolic process#GO:0008152;cellular process#GO:0009987;siderophore metabolic process#GO:0009237;secondary metabolic process#GO:0019748			
ECOLI|EnsemblGenome=b2019|UniProtKB=P60757	P60757	hisG	PTHR21403:SF8	ATP PHOSPHORIBOSYLTRANSFERASE  ATP-PRTASE	ATP PHOSPHORIBOSYLTRANSFERASE	glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763	proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;aromatic amino acid biosynthetic process#GO:0009073		glycosyltransferase#PC00111	Histidine biosynthesis#P02747>ATP phosphoribosyl transferase#P02987
ECOLI|EnsemblGenome=b1704|UniProtKB=P00887	P00887	aroH	PTHR21225:SF6	PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE  DAHP SYNTHETASE	PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, TRP-SENSITIVE	transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824	cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;aromatic amino acid biosynthetic process#GO:0009073;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	aldolase#PC00044;lyase#PC00144	Chorismate biosynthesis#P02734>2-Deoxy-7-phosphoheptulonate synthase#P02871
ECOLI|EnsemblGenome=b3180|UniProtKB=P0AGK4	P0AGK4	yhbY	PTHR40065:SF3	RNA-BINDING PROTEIN YHBY	RNA-BINDING PROTEIN YHBY	binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877	cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;ribosomal large subunit assembly#GO:0000027;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;rRNA metabolic process#GO:0016072;ribosomal small subunit assembly#GO:0000028;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b3574|UniProtKB=P37671	P37671	plaR	PTHR30136:SF19	HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY	HTH-TYPE TRANSCRIPTIONAL REPRESSOR PLAR	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b1769|UniProtKB=P38055	P38055	ydjE	PTHR24064:SF605	SOLUTE CARRIER FAMILY 22 MEMBER	INNER MEMBRANE METABOLITE TRANSPORT PROTEIN YDJE-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b0299|UniProtKB=P0CF79	P0CF79	insF1	PTHR42648:SF5	TRANSPOSASE, PUTATIVE-RELATED	TRANSPOSASE INSF FOR INSERTION SEQUENCE IS3A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b0700|UniProtKB=P16918	P16918	rhsC	PTHR32305:SF18	FAMILY NOT NAMED	PROTEIN RHSA-RELATED					
ECOLI|Gene_OrderedLocusName=JW4302|UniProtKB=P0DP22	P0DP22	yjiQ	PTHR34611:SF5	INACTIVE RECOMBINATION-PROMOTING NUCLEASE-LIKE PROTEIN RPNE	RECOMBINATION-PROMOTING NUCLEASE RPNA-RELATED	nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824	DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139			
ECOLI|EnsemblGenome=b1059|UniProtKB=P40874	P40874	solA	PTHR10961:SF49	PEROXISOMAL SARCOSINE OXIDASE	N-METHYL-L-TRYPTOPHAN OXIDASE	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824		cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	oxidase#PC00175;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0038|UniProtKB=P31572	P31572	caiB	PTHR48228:SF6	SUCCINYL-COA--D-CITRAMALATE COA-TRANSFERASE	L-CARNITINE COA-TRANSFERASE				metabolite interconversion enzyme#PC00262;transferase#PC00220	Coenzyme A linked carnitine metabolism#P02732>L-carnitine dehydratase#P02864;Carnitine metabolism#P02733>Carnitine dehydratase#P02866
ECOLI|EnsemblGenome=b0225|UniProtKB=Q47149	Q47149	yafQ	PTHR40588:SF1	MRNA INTERFERASE TOXIN YAFQ	MRNA INTERFERASE TOXIN YAFQ	catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;endonuclease activity#GO:0004519;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540	gene expression#GO:0010467;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;protein biosynthetic process#GO:0160307;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;RNA metabolic process#GO:0016070;cellular component disassembly#GO:0022411;RNA catabolic process#GO:0006401;translational termination#GO:0006415;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;protein-containing complex disassembly#GO:0032984;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein metabolic process#GO:0019538;translation#GO:0006412	protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;transcription repressor complex#GO:0017053		
ECOLI|EnsemblGenome=b1471|UniProtKB=P76123	P76123	yddK	PTHR45617:SF169	LEUCINE RICH REPEAT FAMILY PROTEIN	LP04042P				scaffold/adaptor protein#PC00226	
ECOLI|EnsemblGenome=b3951|UniProtKB=P32674	P32674	pflD	PTHR43641:SF3	FORMATE ACETYLTRANSFERASE 3-RELATED	DEHYDRATASE PFLD-RELATED			cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	acetyltransferase#PC00038;transferase#PC00220	
ECOLI|EnsemblGenome=b2201|UniProtKB=P33931	P33931	ccmA	PTHR43499:SF1	ABC TRANSPORTER I FAMILY MEMBER 1	ABC TRANSPORTER I FAMILY MEMBER 1		biosynthetic process#GO:0009058;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;metabolic process#GO:0008152;primary metabolic process#GO:0044238		transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0521|UniProtKB=P37306	P37306	allK	PTHR30409:SF2	CARBAMATE KINASE	CARBAMATE KINASE	kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;transferase activity#GO:0016740	catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	transferase#PC00220;kinase#PC00137	
ECOLI|EnsemblGenome=b3620|UniProtKB=P37692	P37692	waaF	PTHR30160:SF7	TETRAACYLDISACCHARIDE 4'-KINASE-RELATED	LIPOPOLYSACCHARIDE HEPTOSYLTRANSFERASE 2	glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740	metabolic process#GO:0008152;lipid metabolic process#GO:0006629;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;oligosaccharide metabolic process#GO:0009311;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;polysaccharide biosynthetic process#GO:0000271;lipopolysaccharide metabolic process#GO:0008653;oligosaccharide biosynthetic process#GO:0009312;primary metabolic process#GO:0044238;liposaccharide metabolic process#GO:1903509;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;lipopolysaccharide core region biosynthetic process#GO:0009244;lipopolysaccharide biosynthetic process#GO:0009103	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	kinase#PC00137;carbohydrate kinase#PC00065	
ECOLI|EnsemblGenome=b1414|UniProtKB=P34209	P34209	ydcF	PTHR30336:SF20	INNER MEMBRANE PROTEIN, PROBABLE PERMEASE	DUF218 DOMAIN-CONTAINING PROTEIN				transporter#PC00227	
ECOLI|EnsemblGenome=b3059|UniProtKB=P60782	P60782	plsY	PTHR30309:SF0	INNER MEMBRANE PROTEIN YGIH	GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b3626|UniProtKB=P27129	P27129	waaJ	PTHR13778:SF64	GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN	LIPOPOLYSACCHARIDE 1,2-GLUCOSYLTRANSFERASE	hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757	macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;lipid biosynthetic process#GO:0008610;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;oligosaccharide metabolic process#GO:0009311;primary metabolic process#GO:0044238;polysaccharide metabolic process#GO:0005976;liposaccharide metabolic process#GO:1903509;lipopolysaccharide core region biosynthetic process#GO:0009244;lipopolysaccharide biosynthetic process#GO:0009103;carbohydrate metabolic process#GO:0005975;polysaccharide biosynthetic process#GO:0000271;oligosaccharide biosynthetic process#GO:0009312;lipopolysaccharide metabolic process#GO:0008653		transferase#PC00220;glycosyltransferase#PC00111	
ECOLI|EnsemblGenome=b0805|UniProtKB=P75780	P75780	fiu	PTHR32552:SF83	FERRICHROME IRON RECEPTOR-RELATED	CATECHOLATE SIDEROPHORE RECEPTOR FIU	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;siderophore-iron transmembrane transporter activity#GO:0015343	monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;siderophore-iron import into cell#GO:0033214;iron coordination entity transport#GO:1901678;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic ion homeostasis#GO:0006873;iron import into cell#GO:0033212;intracellular iron ion homeostasis#GO:0006879;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;iron ion transport#GO:0006826;siderophore-dependent iron import pathway#GO:0180060;cellular localization#GO:0051641;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811	cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;outer membrane#GO:0019867;external encapsulating structure#GO:0030312;cell outer membrane#GO:0009279;membrane#GO:0016020		
ECOLI|EnsemblGenome=b2989|UniProtKB=Q46845	Q46845	yghU	PTHR44051:SF22	GLUTATHIONE S-TRANSFERASE-RELATED	DISULFIDE-BOND OXIDOREDUCTASE YGHU	glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765		intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	transferase#PC00220;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0981|UniProtKB=P38134	P38134	etk	PTHR32309:SF32	TYROSINE-PROTEIN KINASE	TYROSINE-PROTEIN KINASE ETK-RELATED	transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	non-receptor tyrosine protein kinase#PC00168	
ECOLI|EnsemblGenome=b1557|UniProtKB=P36995	P36995	cspB	PTHR11544:SF138	COLD SHOCK DOMAIN CONTAINING PROTEINS	COLD SHOCK PROTEIN CSPA-RELATED					
ECOLI|EnsemblGenome=b3240|UniProtKB=P46481	P46481	aaeB	PTHR30509:SF10	P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT-RELATED	P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT AAEB			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b2536|UniProtKB=Q47142	Q47142	hcaT	PTHR23522:SF10	BLL5896 PROTEIN	3-PHENYLPROPIONIC ACID TRANSPORTER-RELATED			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b0585|UniProtKB=P13039	P13039	fes	PTHR48098:SF3	ENTEROCHELIN ESTERASE-RELATED	IRON(III) ENTEROBACTIN ESTERASE				metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097	
ECOLI|EnsemblGenome=b1678|UniProtKB=P76193	P76193	ynhG	PTHR30582:SF29	L,D-TRANSPEPTIDASE	L,D-TRANSPEPTIDASE YNHG-RELATED	exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824	macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;cell wall macromolecule biosynthetic process#GO:0044038;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;cell wall organization or biogenesis#GO:0071554;peptidoglycan-based cell wall biogenesis#GO:0009273;metabolic process#GO:0008152;peptidoglycan metabolic process#GO:0000270;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;glycosaminoglycan biosynthetic process#GO:0006024;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan metabolic process#GO:0030203;peptidoglycan biosynthetic process#GO:0009252;aminoglycan metabolic process#GO:0006022;cell wall macromolecule metabolic process#GO:0044036;cell wall biogenesis#GO:0042546	cellular anatomical structure#GO:0110165;extracellular region#GO:0005576	protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260	
ECOLI|EnsemblGenome=b4143|UniProtKB=P0A6F5	P0A6F5	groEL	PTHR45633:SF55	60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL	CHAPERONIN GROEL	ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;ATP binding#GO:0005524;binding#GO:0005488;anion binding#GO:0043168	response to heat#GO:0009408;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stimulus#GO:0050896;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538	cytosol#GO:0005829;protein folding chaperone complex#GO:0101031;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		
ECOLI|EnsemblGenome=b3475|UniProtKB=P37623	P37623	acpT	PTHR12215:SF10	PHOSPHOPANTETHEINE TRANSFERASE	L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780	cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;transferase#PC00220	
ECOLI|EnsemblGenome=b1124|UniProtKB=P0AFK6	P0AFK6	potC	PTHR43848:SF5	PUTRESCINE TRANSPORT SYSTEM PERMEASE PROTEIN POTI	SPERMIDINE_PUTRESCINE TRANSPORT SYSTEM PERMEASE PROTEIN POTC	primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;polyamine transmembrane transporter activity#GO:0015203;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b1691|UniProtKB=P76198	P76198	ydiN	PTHR23514:SF3	BYPASS OF STOP CODON PROTEIN 6	BYPASS OF STOP CODON PROTEIN 6			cellular anatomical structure#GO:0110165;membrane#GO:0016020		
ECOLI|EnsemblGenome=b3465|UniProtKB=P0ADX9	P0ADX9	rsmD	PTHR43542:SF1	METHYLTRANSFERASE	METHYLTRANSFERASE	catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;rRNA (guanine) methyltransferase activity#GO:0016435;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a rRNA#GO:0140102	rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;methylation#GO:0032259;macromolecule biosynthetic process#GO:0009059;rRNA base methylation#GO:0070475;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;rRNA methylation#GO:0031167;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840		RNA metabolism protein#PC00031;RNA methyltransferase#PC00033	
ECOLI|EnsemblGenome=b3019|UniProtKB=P0AFI2	P0AFI2	parC	PTHR43493:SF1	DNA GYRASE/TOPOISOMERASE SUBUNIT A	DNA TOPOISOMERASE 4 SUBUNIT A	ion binding#GO:0043167;nucleic acid binding#GO:0003676;anion binding#GO:0043168;small molecule binding#GO:0036094;DNA binding#GO:0003677;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;isomerase activity#GO:0016853;ATP-dependent activity#GO:0140657;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;ATP binding#GO:0005524;ATP-dependent activity, acting on DNA#GO:0008094;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;nucleic acid conformation isomerase activity#GO:0120545;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;catalytic activity, acting on DNA#GO:0140097;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363	DNA metabolic process#GO:0006259;metabolic process#GO:0008152;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139	catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	DNA topoisomerase#PC00017;DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b0439|UniProtKB=P0A9M0	P0A9M0	lon	PTHR10046:SF56	ATP DEPENDENT LON PROTEASE FAMILY MEMBER	LON PROTEASE	peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824			serine protease#PC00203;protease#PC00190	
ECOLI|EnsemblGenome=b2614|UniProtKB=P09372	P09372	grpE	PTHR21237:SF40	GRPE PROTEIN	GRPE PROTEIN HOMOLOG	nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772			transporter#PC00227;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b0115|UniProtKB=P06959	P06959	aceF	PTHR43178:SF2	LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED CHAIN ALPHA_KETOACID DEHYDROGENASE COMPLEX	DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX	catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740	nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;pyruvate metabolic process#GO:0006090;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;aerobic respiration#GO:0009060;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;acetyl-CoA metabolic process#GO:0006084	oxidoreductase complex#GO:1990204;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;acetyltransferase complex#GO:1902493	transferase#PC00220;acetyltransferase#PC00038	
ECOLI|EnsemblGenome=b4176|UniProtKB=P0AF73	P0AF73	yjeT	PTHR38602:SF1	INNER MEMBRANE PROTEIN-RELATED	BSL6507 PROTEIN					
ECOLI|EnsemblGenome=b2367|UniProtKB=P52600	P52600	emrY	PTHR23501:SF174	MAJOR FACILITATOR SUPERFAMILY	MULTIDRUG EXPORT PROTEIN EMRB-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b1439|UniProtKB=P77730	P77730	ydcR	PTHR42790:SF9	AMINOTRANSFERASE	GNTR-FAMILY REGULATORY PROTEIN	transaminase activity#GO:0008483;catalytic activity#GO:0003824;transferase activity#GO:0016740			transaminase#PC00216	
ECOLI|EnsemblGenome=b1312|UniProtKB=P77716	P77716	ycjP	PTHR32243:SF18	MALTOSE TRANSPORT SYSTEM PERMEASE-RELATED	MALTOSE TRANSPORT SYSTEM PERMEASE PROTEIN YCJP	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	primary active transporter#PC00068;transporter#PC00227	
ECOLI|EnsemblGenome=b2994|UniProtKB=P0ACE0	P0ACE0	hybC	PTHR42958:SF1	HYDROGENASE-2 LARGE CHAIN	HYDROGENASE-2 LARGE CHAIN				oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2064|UniProtKB=P28249	P28249	asmA	PTHR30441:SF4	DUF748 DOMAIN-CONTAINING PROTEIN	PROTEIN ASMA		regulation of cellular process#GO:0050794;regulation of protein localization#GO:0032880;biological regulation#GO:0065007;regulation of establishment of protein localization#GO:0070201;regulation of localization#GO:0032879;regulation of biological process#GO:0050789	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b4265|UniProtKB=P39344	P39344	idnT	PTHR30354:SF9	GNT FAMILY GLUCONATE TRANSPORTER	GNT-II SYSTEM L-IDONATE TRANSPORTER	transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;monocarboxylic acid transmembrane transporter activity#GO:0008028;carbohydrate transmembrane transporter activity#GO:0015144	cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carboxylic acid transmembrane transport#GO:1905039;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;carbohydrate transport#GO:0008643;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monocarboxylic acid transport#GO:0015718	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	secondary carrier transporter#PC00258;transporter#PC00227	
ECOLI|EnsemblGenome=b0995|UniProtKB=P38684	P38684	torR	PTHR48111:SF58	REGULATOR OF RPOS	TORCAD OPERON TRANSCRIPTIONAL REGULATORY PROTEIN TORR	sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007	protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b1336|UniProtKB=P46133	P46133	abgT	PTHR30282:SF0	P-AMINOBENZOYL GLUTAMATE TRANSPORTER	P-AMINOBENZOYL-GLUTAMATE TRANSPORT PROTEIN	secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;dipeptide transmembrane transporter activity#GO:0071916;oligopeptide transmembrane transporter activity#GO:0035673;active transmembrane transporter activity#GO:0022804;dicarboxylic acid transmembrane transporter activity#GO:0005310;carboxylic acid transmembrane transporter activity#GO:0046943	nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;dicarboxylic acid transport#GO:0006835;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;establishment of localization#GO:0051234;dipeptide transport#GO:0042938;localization#GO:0051179;oligopeptide transport#GO:0006857	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b2742|UniProtKB=P0ADA3	P0ADA3	nlpD	PTHR21666:SF263	PEPTIDASE-RELATED	MUREIN HYDROLASE ACTIVATOR NLPD	catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237		outer membrane#GO:0019867;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;cell outer membrane#GO:0009279;membrane#GO:0016020;cellular anatomical structure#GO:0110165;cell division site#GO:0032153;cell envelope#GO:0030313	metalloprotease#PC00153;protease#PC00190	
ECOLI|EnsemblGenome=b1888|UniProtKB=P07363	P07363	cheA	PTHR43395:SF10	SENSOR HISTIDINE KINASE CHEA	CHEMOTAXIS PROTEIN CHEA	molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;protein histidine kinase activity#GO:0004673;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphorelay sensor kinase activity#GO:0000155;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773	intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of response to stimulus#GO:0048583;regulation of locomotion#GO:0040012;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of response to external stimulus#GO:0032101;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;phosphorelay signal transduction system#GO:0000160;regulation of chemotaxis#GO:0050920		histidine kinase receptor of two-component system#PC00265	
ECOLI|EnsemblGenome=b3646|UniProtKB=P0AGM2	P0AGM2	yicG	PTHR30506:SF3	INNER MEMBRANE PROTEIN	UPF0126 INNER MEMBRANE PROTEIN YADS-RELATED			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b1447|UniProtKB=P76111	P76111	ydcZ	PTHR34821:SF2	INNER MEMBRANE PROTEIN YDCZ	INNER MEMBRANE PROTEIN YDCZ			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b1624|UniProtKB=P77376	P77376	ydgJ	PTHR43708:SF5	CONSERVED EXPRESSED OXIDOREDUCTASE (EUROFUNG)	SCYLLO-INOSITOL 2-DEHYDROGENASE (NADP(+)) IOLW				oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2553|UniProtKB=P0A9Z1	P0A9Z1	glnB	PTHR30115:SF11	NITROGEN REGULATORY PROTEIN P-II	NITROGEN REGULATORY PROTEIN P-II HOMOLOG	purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;molecular function regulator activity#GO:0098772;nucleotide binding#GO:0000166;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ATP binding#GO:0005524;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;enzyme regulator activity#GO:0030234	biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	protein-binding activity modulator#PC00095	
ECOLI|EnsemblGenome=b1804|UniProtKB=P09155	P09155	rnd	PTHR47649:SF1	RIBONUCLEASE D	RIBONUCLEASE D	nuclease activity#GO:0004518;hydrolase activity#GO:0016787;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640	tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA 3'-end processing#GO:0042780;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774		RNA metabolism protein#PC00031;exoribonuclease#PC00099	
ECOLI|EnsemblGenome=b2297|UniProtKB=P0A9M8	P0A9M8	pta	PTHR43356:SF3	PHOSPHATE ACETYLTRANSFERASE	PHOSPHATE ACETYLTRANSFERASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746			transferase#PC00220;acetyltransferase#PC00038	Acetate utilization#P02722>Phosphate acetyltransferase#P02802
ECOLI|EnsemblGenome=b4036|UniProtKB=P02943	P02943	lamB	PTHR38762:SF1	CRYPTIC OUTER MEMBRANE PORIN BGLH-RELATED	CRYPTIC OUTER MEMBRANE PORIN BGLH-RELATED	wide pore channel activity#GO:0022829;carbohydrate transmembrane transporter activity#GO:0015144;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	macromolecule localization#GO:0033036;carbohydrate transport#GO:0008643;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234	cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;external encapsulating structure#GO:0030312;membrane#GO:0016020;cell outer membrane#GO:0009279;extracellular region#GO:0005576;outer membrane#GO:0019867		
ECOLI|EnsemblGenome=b3523|UniProtKB=P37643	P37643	yhjE	PTHR43045:SF2	SHIKIMATE TRANSPORTER	INNER MEMBRANE METABOLITE TRANSPORT PROTEIN YHJE	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b4046|UniProtKB=P0AC51	P0AC51	zur	PTHR33202:SF6	ZINC UPTAKE REGULATION PROTEIN	ZINC UPTAKE REGULATION PROTEIN	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;metal ion binding#GO:0046872;sequence-specific DNA binding#GO:0043565;transition metal ion binding#GO:0046914;transcription cis-regulatory region binding#GO:0000976;ion binding#GO:0043167;small molecule binding#GO:0036094;nucleic acid binding#GO:0003676;cation binding#GO:0043169;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;zinc ion binding#GO:0008270;sequence-specific double-stranded DNA binding#GO:1990837	regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b2785|UniProtKB=P55135	P55135	rlmD	PTHR11061:SF30	RNA M5U METHYLTRANSFERASE	TRNA (URACIL(54)-C(5))-METHYLTRANSFERASE				RNA methyltransferase#PC00033	
ECOLI|EnsemblGenome=b3325|UniProtKB=P45758	P45758	gspD	PTHR30332:SF24	PROBABLE GENERAL SECRETION PATHWAY PROTEIN D	SECRETIN GSPD-RELATED		establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;protein secretion by the type II secretion system#GO:0015628;protein transmembrane transport#GO:0071806;transport#GO:0006810;cellular process#GO:0009987;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;protein transport#GO:0015031;secretion by cell#GO:0032940;secretion#GO:0046903;transmembrane transport#GO:0055085;localization#GO:0051179;protein secretion#GO:0009306;export from cell#GO:0140352;protein localization to extracellular region#GO:0071692	type II protein secretion system complex#GO:0015627;protein-containing complex#GO:0032991	transporter#PC00227	
ECOLI|EnsemblGenome=b0931|UniProtKB=P18133	P18133	pncB	PTHR11098:SF1	NICOTINATE PHOSPHORIBOSYLTRANSFERASE	NICOTINATE PHOSPHORIBOSYLTRANSFERASE	catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879	NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine-containing compound metabolic process#GO:0072524;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	glycosyltransferase#PC00111;transferase#PC00220	
ECOLI|EnsemblGenome=b2702|UniProtKB=P56579	P56579	srlA	PTHR40399:SF1	PTS SYSTEM GLUCITOL/SORBITOL-SPECIFIC EIIC COMPONENT	PTS SYSTEM GLUCITOL_SORBITOL-SPECIFIC EIIC COMPONENT		transport#GO:0006810;carbohydrate transport#GO:0008643;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;transmembrane transport#GO:0055085;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739			
ECOLI|EnsemblGenome=b3452|UniProtKB=P10905	P10905	ugpA	PTHR43227:SF9	BLL4140 PROTEIN	SN-GLYCEROL-3-PHOSPHATE TRANSPORT SYSTEM PERMEASE PROTEIN UGPA	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate derivative transmembrane transporter activity#GO:1901505;organophosphate ester transmembrane transporter activity#GO:0015605		cellular anatomical structure#GO:0110165;membrane#GO:0016020		
ECOLI|EnsemblGenome=b1558|UniProtKB=P0A976	P0A976	cspF	PTHR11544:SF138	COLD SHOCK DOMAIN CONTAINING PROTEINS	COLD SHOCK PROTEIN CSPA-RELATED					
ECOLI|EnsemblGenome=b1879|UniProtKB=P76298	P76298	flhA	PTHR30161:SF1	FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED	FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED		organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;bacterial-type flagellum assembly#GO:0044780;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell projection assembly#GO:0030031;cellular process#GO:0009987;cell projection organization#GO:0030030;cellular component assembly#GO:0022607	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b0168|UniProtKB=P0AE18	P0AE18	map	PTHR43330:SF27	METHIONINE AMINOPEPTIDASE	METHIONINE AMINOPEPTIDASE	catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006		cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	metalloprotease#PC00153	
ECOLI|EnsemblGenome=b2288|UniProtKB=P0AFC3	P0AFC3	nuoA	PTHR11058:SF21	NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 3	NADH-QUINONE OXIDOREDUCTASE SUBUNIT A	oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324;oxidoreductase activity, acting on NAD(P)H#GO:0016651;NADH dehydrogenase activity#GO:0003954		respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0678|UniProtKB=P0A759	P0A759	nagB	PTHR11280:SF5	GLUCOSAMINE-6-PHOSPHATE ISOMERASE	GLUCOSAMINE-6-PHOSPHATE DEAMINASE	deaminase activity#GO:0019239;identical protein binding#GO:0042802;protein binding#GO:0005515;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;binding#GO:0005488;catalytic activity#GO:0003824	carbohydrate derivative metabolic process#GO:1901135;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino sugar catabolic process#GO:0046348	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	isomerase#PC00135	N-acetylglucosamine metabolism#P02756>Glucosamine-6-phosphate deaminase#P03041
ECOLI|EnsemblGenome=b1218|UniProtKB=P39163	P39163	chaC	PTHR12192:SF2	CATION TRANSPORT PROTEIN CHAC-RELATED	GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 2					
ECOLI|EnsemblGenome=b3376|UniProtKB=P45545	P45545	yhfS	PTHR43797:SF2	HOMOCYSTEINE/CYSTEINE SYNTHASE	HOMOCYSTEINE_CYSTEINE SYNTHASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829	small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b0296|UniProtKB=P0A7N1	P0A7N1	ykgM	PTHR33280:SF1	50S RIBOSOMAL PROTEIN L31, CHLOROPLASTIC	LARGE RIBOSOMAL SUBUNIT PROTEIN BL31C	structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198	protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059		ribosomal protein#PC00202;translational protein#PC00263	
ECOLI|EnsemblGenome=b4465|UniProtKB=P52048	P52048	yggP	PTHR43401:SF6	L-THREONINE 3-DEHYDROGENASE	L-THREONINE 3-DEHYDROGENASE	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616	oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2428|UniProtKB=P76535	P76535	murQ	PTHR10088:SF6	GLUCOKINASE REGULATORY PROTEIN	N-ACETYLMURAMIC ACID 6-PHOSPHATE ETHERASE				protein-binding activity modulator#PC00095	
ECOLI|EnsemblGenome=b0483|UniProtKB=P0A9T6	P0A9T6	ybaQ	PTHR36924:SF1	ANTITOXIN HIGA-1	ANTITOXIN HIGA-1		regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222			
ECOLI|EnsemblGenome=b3226|UniProtKB=P0A8W0	P0A8W0	nanR	PTHR43537:SF53	TRANSCRIPTIONAL REGULATOR, GNTR FAMILY	HTH-TYPE TRANSCRIPTIONAL REPRESSOR NANR	DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556		helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b2730|UniProtKB=P24193	P24193	hypE	PTHR30303:SF0	HYDROGENASE ISOENZYMES FORMATION PROTEIN HYPE	CARBAMOYL DEHYDRATASE HYPE		protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987			
ECOLI|EnsemblGenome=b2373|UniProtKB=P0AFI0	P0AFI0	oxc	PTHR43710:SF8	2-HYDROXYACYL-COA LYASE	OXALYL-COA DECARBOXYLASE	small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;cation binding#GO:0043169	monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436		lyase#PC00144;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b4710|UniProtKB=A0A385XJL4	A0A385XJL4	insB9	PTHR33293:SF1	INSERTION ELEMENT IS1 1 PROTEIN INSB-RELATED	INSERTION ELEMENT IS1 1 PROTEIN INSB-RELATED					
ECOLI|EnsemblGenome=b1079|UniProtKB=P0A6S0	P0A6S0	flgH	PTHR34933:SF3	FLAGELLAR L-RING PROTEIN	FLAGELLAR L-RING PROTEIN				structural protein#PC00211	
ECOLI|EnsemblGenome=b0650|UniProtKB=P77319	P77319	hscC	PTHR19375:SF575	HEAT SHOCK PROTEIN 70KDA	CHAPERONE PROTEIN HSCC	ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824	gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein refolding#GO:0042026;metabolic process#GO:0008152		chaperone#PC00072;Hsp70 family chaperone#PC00027	
ECOLI|EnsemblGenome=b0790|UniProtKB=P0AAW1	P0AAW1	ybhP	PTHR15822:SF27	TRAF AND TNF RECEPTOR-ASSOCIATED PROTEIN	UPF0294 PROTEIN VC_2238					
ECOLI|EnsemblGenome=b0733|UniProtKB=P0ABJ9	P0ABJ9	cydA	PTHR30365:SF0	CYTOCHROME D UBIQUINOL OXIDASE	CYTOCHROME BD-I UBIQUINOL OXIDASE SUBUNIT 1	heme binding#GO:0020037;oxidoreductase activity, acting on diphenols and related substances as donors#GO:0016679;catalytic activity#GO:0003824;binding#GO:0005488;tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491	generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900	membrane#GO:0016020;catalytic complex#GO:1902494;cytochrome complex#GO:0070069;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886	oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2379|UniProtKB=P77434	P77434	alaC	PTHR42832:SF1	AMINO ACID AMINOTRANSFERASE	GLUTAMATE-PYRUVATE AMINOTRANSFERASE ALAC	transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824	amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394		transaminase#PC00216	
ECOLI|EnsemblGenome=b1645|UniProtKB=P76186	P76186	ydhK	PTHR30509:SF40	P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT-RELATED	FUSC FAMILY PROTEIN			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b3353|UniProtKB=P45524	P45524	yheT	PTHR10794:SF98	ABHYDROLASE DOMAIN-CONTAINING PROTEIN	ALPHA_BETA HYDROLASE 1, ISOFORM A	catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787	small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid biosynthetic process#GO:0072330;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056		protease#PC00190;serine protease#PC00203	
ECOLI|EnsemblGenome=b0508|UniProtKB=P30147	P30147	hyi	PTHR43489:SF14	ISOMERASE	FRUCTOSELYSINE 3-EPIMERASE-RELATED	isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;glyoxylate metabolic process#GO:0046487;small molecule metabolic process#GO:0044281;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787		metabolite interconversion enzyme#PC00262;isomerase#PC00135	
ECOLI|EnsemblGenome=b1795|UniProtKB=P64485	P64485	yeaQ	PTHR33884:SF4	UPF0410 PROTEIN YMGE	UPF0410 PROTEIN YEAQ					
ECOLI|EnsemblGenome=b2285|UniProtKB=P0AFD1	P0AFD1	nuoE	PTHR10371:SF4	NADH DEHYDROGENASE  UBIQUINONE  FLAVOPROTEIN 2, MITOCHONDRIAL	NADH-QUINONE OXIDOREDUCTASE SUBUNIT E	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;NADH dehydrogenase activity#GO:0003954	metabolic process#GO:0008152;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980		oxidoreductase#PC00176;dehydrogenase#PC00092	Parkinson disease#P00049>Complex I#P01237
ECOLI|EnsemblGenome=b0403|UniProtKB=P21517	P21517	malZ	PTHR10357:SF210	ALPHA-GLUCOSIDASE FAMILY MEMBER	MALTODEXTRIN GLUCOSIDASE	hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;alpha-glucosidase activity#GO:0090599;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;glucosidase activity#GO:0015926;catalytic activity#GO:0003824			metabolite interconversion enzyme#PC00262;amylase#PC00048	
ECOLI|EnsemblGenome=b2033|UniProtKB=P37750	P37750	wbbJ	PTHR23416:SF78	SIALIC ACID SYNTHASE-RELATED	LIPOPOLYSACCHARIDE BIOSYNTHESIS O-ACETYL TRANSFERASE WBBJ-RELATED				metabolite interconversion enzyme#PC00262;transferase#PC00220	
ECOLI|EnsemblGenome=b1297|UniProtKB=P78061	P78061	puuA	PTHR43785:SF16	GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE	GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE PUUA		proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752		ligase#PC00142	Glutamine glutamate conversion#P02745>Glutamine synthase#P04483;Glutamine glutamate conversion#P02745>Glutamine synthetase#P02968
ECOLI|EnsemblGenome=b0315|UniProtKB=P21514	P21514	pdeL	PTHR33121:SF71	CYCLIC DI-GMP PHOSPHODIESTERASE PDEF	CYCLIC DI-GMP PHOSPHODIESTERASE PDEL-RELATED	hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121	
ECOLI|EnsemblGenome=b0428|UniProtKB=P0AEA5	P0AEA5	cyoE	PTHR43448:SF10	PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL	PROTOHEME IX FARNESYLTRANSFERASE	transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;catalytic activity#GO:0003824	pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;cellular process#GO:0009987;tetrapyrrole biosynthetic process#GO:0033014;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;porphyrin-containing compound biosynthetic process#GO:0006779	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	acyltransferase#PC00042;transferase#PC00220;metabolite interconversion enzyme#PC00262	Heme biosynthesis#P02746>Protoheme IX farnesyl transferase#P02982
ECOLI|EnsemblGenome=b1787|UniProtKB=P64483	P64483	proXp-y	PTHR30411:SF9	CYTOPLASMIC PROTEIN	MULTIFUNCTIONAL SER_THR-TRNA DEACYLASE PROXP-Y	catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;deacylase activity#GO:0160215;catalytic activity#GO:0003824	metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;regulation of biological quality#GO:0065008;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007			
ECOLI|EnsemblGenome=b3216|UniProtKB=P45420	P45420	yhcD	PTHR30451:SF8	OUTER MEMBRANE USHER PROTEIN	OUTER MEMBRANE FIMBRIAL USHER PROTEIN	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829	cell adhesion#GO:0007155;cellular process#GO:0009987	cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane#GO:0019867;extracellular region#GO:0005576;cell outer membrane#GO:0009279;membrane#GO:0016020;external encapsulating structure#GO:0030312		
ECOLI|EnsemblGenome=b0181|UniProtKB=P0A722	P0A722	lpxA	PTHR43480:SF1	ACYL-[ACYL-CARRIER-PROTEIN]--UDP-N-ACETYLGLUCOSAMINE O-ACYLTRANSFERASE	ACYL-[ACYL-CARRIER-PROTEIN]--UDP-N-ACETYLGLUCOSAMINE O-ACYLTRANSFERASE	acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747			transferase#PC00220;acyltransferase#PC00042	
ECOLI|EnsemblGenome=b0121|UniProtKB=P09158	P09158	speE	PTHR11558:SF11	SPERMIDINE/SPERMINE SYNTHASE	SPERMIDINE SYNTHASE	transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740	biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;polyamine biosynthetic process#GO:0006596;cellular process#GO:0009987;polyamine metabolic process#GO:0006595;amine metabolic process#GO:0009308;metabolic process#GO:0008152	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	transferase#PC00220	
ECOLI|EnsemblGenome=b0627|UniProtKB=P0A843	P0A843	tatE	PTHR42982:SF5	SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATA	SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATE	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transmembrane protein transporter activity#GO:0008320	intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;protein transmembrane transport#GO:0071806;transport#GO:0006810;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036	plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1863|UniProtKB=P0A814	P0A814	ruvC	PTHR30194:SF3	CROSSOVER JUNCTION ENDODEOXYRIBONUCLEASE RUVC	CROSSOVER JUNCTION ENDODEOXYRIBONUCLEASE RUVC				endodeoxyribonuclease#PC00093	
ECOLI|EnsemblGenome=b0696|UniProtKB=P03961	P03961	kdpC	PTHR30042:SF2	POTASSIUM-TRANSPORTING ATPASE C CHAIN	POTASSIUM-TRANSPORTING ATPASE KDPC SUBUNIT	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;metal ion transmembrane transporter activity#GO:0046873;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079	potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810	ATPase dependent transmembrane transport complex#GO:0098533;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cation-transporting ATPase complex#GO:0090533;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796		
ECOLI|EnsemblGenome=b3480|UniProtKB=P33594	P33594	nikE	PTHR43776:SF16	TRANSPORT ATP-BINDING PROTEIN	D,D-DIPEPTIDE TRANSPORT ATP-BINDING PROTEIN DDPF-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate derivative transmembrane transporter activity#GO:1901505		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b2917|UniProtKB=P27253	P27253	scpA	PTHR48101:SF5	METHYLMALONYL-COA MUTASE, MITOCHONDRIAL-RELATED	METHYLMALONYL-COA MUTASE	intramolecular transferase activity#GO:0016866;small molecule binding#GO:0036094;catalytic activity#GO:0003824;binding#GO:0005488;tetrapyrrole binding#GO:0046906;isomerase activity#GO:0016853;heterocyclic compound binding#GO:1901363	organophosphate catabolic process#GO:0046434;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine-containing compound catabolic process#GO:0072523;sulfur compound catabolic process#GO:0044273;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;sulfur compound metabolic process#GO:0006790;lipid catabolic process#GO:0016042;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	mutase#PC00160;isomerase#PC00135;metabolite interconversion enzyme#PC00262	Methylmalonyl pathway#P02755>Methylmalonyl-CoA mutase#P03034;Succinate to proprionate conversion#P02777>Methylmalonyl-CoA mutase#P03161
ECOLI|EnsemblGenome=b1945|UniProtKB=P06974	P06974	fliM	PTHR30034:SF3	FLAGELLAR MOTOR SWITCH PROTEIN FLIM	FLAGELLAR MOTOR SWITCH PROTEIN FLIM		positive chemotaxis#GO:0050918;cellular process#GO:0009987;cell motility#GO:0048870;taxis#GO:0042330;response to chemical#GO:0042221;response to stimulus#GO:0050896;locomotion#GO:0040011;bacterial-type flagellum-dependent swarming motility#GO:0071978;archaeal or bacterial-type flagellum-dependent cell motility#GO:0097588;chemotaxis#GO:0006935;cilium or flagellum-dependent cell motility#GO:0001539;bacterial-type flagellum-dependent cell motility#GO:0071973;response to external stimulus#GO:0009605		structural protein#PC00211	
ECOLI|EnsemblGenome=b2030|UniProtKB=P0CE54	P0CE54	insH7	PTHR35604:SF2	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097	nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b0732|UniProtKB=P54746	P54746	mngB	PTHR46017:SF2	ALPHA-MANNOSIDASE 2C1	MANNOSYLGLYCERATE HYDROLASE	hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553	oligosaccharide metabolic process#GO:0009311;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;carbohydrate metabolic process#GO:0005975;oligosaccharide catabolic process#GO:0009313;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238			
ECOLI|EnsemblGenome=b1699|UniProtKB=P77337	P77337	ydiS	PTHR43624:SF2	ELECTRON TRANSFER FLAVOPROTEIN-QUINONE OXIDOREDUCTASE YDIS-RELATED	ELECTRON TRANSFER FLAVOPROTEIN-QUINONE OXIDOREDUCTASE YDIS-RELATED				oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3881|UniProtKB=P32141	P32141	yihT	PTHR39340:SF1	SULFOFRUCTOSEPHOSPHATE ALDOLASE	SULFOFRUCTOSEPHOSPHATE ALDOLASE	aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824	catabolic process#GO:0009056;sulfur compound catabolic process#GO:0044273;carbohydrate derivative catabolic process#GO:1901136;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987		metabolite interconversion enzyme#PC00262;aldolase#PC00044	
ECOLI|EnsemblGenome=b2069|UniProtKB=P36928	P36928	yegD	PTHR19375:SF355	HEAT SHOCK PROTEIN 70KDA	HEAT SHOCK PROTEIN	hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;protein binding#GO:0005515	protein refolding#GO:0042026;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238		chaperone#PC00072;Hsp70 family chaperone#PC00027	
ECOLI|EnsemblGenome=b0341|UniProtKB=P17583	P17583	cynX	PTHR23523:SF1	MAJOR FACILITATOR SUPERFAMILY (MFS) TRANSPORTER-RELATED	CYANATE TRANSPORT PROTEIN CYNX		catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b4391|UniProtKB=P0A9W3	P0A9W3	ettA	PTHR43858:SF1	ENERGY-DEPENDENT TRANSLATIONAL THROTTLE PROTEIN ETTA	ENERGY-DEPENDENT TRANSLATIONAL THROTTLE PROTEIN ETTA	ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;binding#GO:0005488	negative regulation of translation#GO:0017148;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556		translation elongation factor#PC00222	
ECOLI|EnsemblGenome=b1605|UniProtKB=P0AAE5	P0AAE5	ydgI	PTHR42770:SF4	AMINO ACID TRANSPORTER-RELATED	ARGININE_ORNITHINE ANTIPORTER-RELATED	active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297;amino acid transmembrane transporter activity#GO:0015171		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	amino acid transporter#PC00046;secondary carrier transporter#PC00258;transporter#PC00227	
ECOLI|EnsemblGenome=b3140|UniProtKB=P42911	P42911	agaD	PTHR32502:SF5	N-ACETYLGALACTOSAMINE PERMEASE II COMPONENT-RELATED	N-ACETYLGALACTOSAMINE PERMEASE IID COMPONENT-RELATED	transferase activity, transferring phosphorus-containing groups#GO:0016772;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transferase activity#GO:0016740;catalytic activity#GO:0003824;active transmembrane transporter activity#GO:0022804;sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144;phosphotransferase activity, alcohol group as acceptor#GO:0016773	cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739;transport#GO:0006810;carbohydrate transport#GO:0008643;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;establishment of localization#GO:0051234;import into cell#GO:0098657;transmembrane transport#GO:0055085;localization#GO:0051179	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b1865|UniProtKB=P0AFC0	P0AFC0	nudB	PTHR43736:SF1	ADP-RIBOSE PYROPHOSPHATASE	DIHYDRONEOPTERIN TRIPHOSPHATE DIPHOSPHATASE	hydrolase activity#GO:0016787;nucleoside triphosphate diphosphatase activity#GO:0047429;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817	carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;tetrahydrofolate biosynthetic process#GO:0046654;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;tetrahydrofolate metabolic process#GO:0046653		phosphatase#PC00181;hydrolase#PC00121	
ECOLI|EnsemblGenome=b4709|UniProtKB=A0A385XJ53	A0A385XJ53	insA9	PTHR47923:SF1	INSERTION ELEMENT IS1 1 PROTEIN INSA-RELATED	INSERTION ELEMENT IS1 1 PROTEIN INSA-RELATED		DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139			
ECOLI|EnsemblGenome=b0778|UniProtKB=P13000	P13000	bioD1	PTHR43210:SF5	DETHIOBIOTIN SYNTHETASE	ATP-DEPENDENT DETHIOBIOTIN SYNTHETASE BIOD 1	ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824	cellular process#GO:0009987;biotin metabolic process#GO:0006768;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;monocarboxylic acid metabolic process#GO:0032787;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		Biotin biosynthesis#P02731>Dethiobiotin synthase#P02859
ECOLI|EnsemblGenome=b1418|UniProtKB=P0ABE5	P0ABE5	cybB	PTHR30529:SF4	CYTOCHROME B561	SUPEROXIDE OXIDASE CYBB	tetrapyrrole binding#GO:0046906;binding#GO:0005488;heme binding#GO:0020037		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b4102|UniProtKB=P16684	P16684	phnF	PTHR44846:SF19	MANNOSYL-D-GLYCERATE TRANSPORT/METABOLISM SYSTEM REPRESSOR MNGR-RELATED	TRANSCRIPTIONAL REGULATOR PHNF-RELATED				helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b3202|UniProtKB=P24255	P24255	rpoN	PTHR32248:SF4	RNA POLYMERASE SIGMA-54 FACTOR	RNA POLYMERASE SIGMA-54 FACTOR	sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700	regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355	protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993	helix-turn-helix transcription factor#PC00116;Sigma factor#PC00267;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b1694|UniProtKB=P37766	P37766	ydiF	PTHR43293:SF1	ACETATE COA-TRANSFERASE YDIF	ACETATE COA-TRANSFERASE YDIF				transferase#PC00220	
ECOLI|EnsemblGenome=b0301|UniProtKB=P75685	P75685	rclC	PTHR40106:SF1	INNER MEMBRANE PROTEIN RCLC	INNER MEMBRANE PROTEIN RCLC		response to reactive oxygen species#GO:0000302;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to oxidative stress#GO:0006979;response to oxygen-containing compound#GO:1901700;response to stress#GO:0006950	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b2764|UniProtKB=P38038	P38038	cysJ	PTHR19384:SF128	NITRIC OXIDE SYNTHASE-RELATED	SULFITE REDUCTASE [NADPH] FLAVOPROTEIN ALPHA-COMPONENT				oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	Sulfate assimilation#P02778>Sulfite reductase#P03165
ECOLI|EnsemblGenome=b1091|UniProtKB=P0A6R0	P0A6R0	fabH	PTHR43091:SF1	3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE	BETA-KETOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE III, CHLOROPLASTIC	acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746	lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281		acetyltransferase#PC00038	
ECOLI|EnsemblGenome=b0052|UniProtKB=P19624	P19624	pdxA	PTHR30004:SF5	4-HYDROXYTHREONINE-4-PHOSPHATE DEHYDROGENASE	4-HYDROXYTHREONINE-4-PHOSPHATE DEHYDROGENASE	catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614	phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;pyridine-containing compound metabolic process#GO:0072524;organophosphate biosynthetic process#GO:0090407		oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b1402|UniProtKB=P0CF54	P0CF54	insD2	PTHR37936:SF3	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b3243|UniProtKB=P67662	P67662	aaeR	PTHR30126:SF87	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL ACTIVATOR AAER	binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252		gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b0095|UniProtKB=P0A9A6	P0A9A6	ftsZ	PTHR30314:SF35	CELL DIVISION PROTEIN FTSZ-RELATED	CELL DIVISION PROTEIN FTSZ	GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111	cell division#GO:0051301;cellular process#GO:0009987	division septum#GO:0000935;cell septum#GO:0030428;cellular anatomical structure#GO:0110165;cell division site#GO:0032153;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		
ECOLI|EnsemblGenome=b3516|UniProtKB=P37639	P37639	gadX	PTHR47894:SF4	HTH-TYPE TRANSCRIPTIONAL REGULATOR GADX	HTH-TYPE TRANSCRIPTIONAL REGULATOR GADX	transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837			DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b0496|UniProtKB=P77504	P77504	ybbP	PTHR30287:SF1	MEMBRANE COMPONENT OF PREDICTED ABC SUPERFAMILY METABOLITE UPTAKE TRANSPORTER	ABC3 TRANSPORTER PERMEASE C-TERMINAL DOMAIN-CONTAINING PROTEIN			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b1290|UniProtKB=P0AAH8	P0AAH8	sapF	PTHR43776:SF4	TRANSPORT ATP-BINDING PROTEIN	PUTRESCINE EXPORT SYSTEM ATP-BINDING PROTEIN SAPF	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;polyamine transmembrane transporter activity#GO:0015203		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0055|UniProtKB=P31680	P31680	djlA	PTHR24074:SF61	CO-CHAPERONE PROTEIN DJLA	DNAJ HOMOLOG SUBFAMILY B MEMBER 9				chaperone#PC00072	
ECOLI|Gene_OrderedLocusName=JW1570|UniProtKB=P0CF60	P0CF60	insD8	PTHR37936:SF3	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b1499|UniProtKB=P76135	P76135	ydeO	PTHR43280:SF33	ARAC-FAMILY TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR APPY-RELATED	nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007		DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b2333|UniProtKB=P76499	P76499	yfcP	PTHR33420:SF9	FIMBRIAL SUBUNIT ELFA-RELATED	MINOR FIMBRIAL SUBUNIT		cell-substrate adhesion#GO:0031589;cell adhesion#GO:0007155;cellular process#GO:0009987;single-species biofilm formation#GO:0044010	cellular anatomical structure#GO:0110165;cell projection#GO:0042995		
ECOLI|EnsemblGenome=b2455|UniProtKB=P77445	P77445	eutE	PTHR11699:SF68	ALDEHYDE DEHYDROGENASE-RELATED	ACETALDEHYDE DEHYDROGENASE (ACETYLATING) EUTE	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b0264|UniProtKB=P0CF26	P0CF26	insB2	PTHR33293:SF1	INSERTION ELEMENT IS1 1 PROTEIN INSB-RELATED	INSERTION ELEMENT IS1 1 PROTEIN INSB-RELATED					
ECOLI|EnsemblGenome=b2231|UniProtKB=P0AES4	P0AES4	gyrA	PTHR43493:SF5	DNA GYRASE/TOPOISOMERASE SUBUNIT A	DNA GYRASE SUBUNIT A, CHLOROPLASTIC_MITOCHONDRIAL	isomerase activity#GO:0016853;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;DNA binding#GO:0003677;anion binding#GO:0043168;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;ion binding#GO:0043167;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;nucleic acid conformation isomerase activity#GO:0120545;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;ATP-dependent activity, acting on DNA#GO:0008094;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;ATP-dependent activity#GO:0140657	metabolic process#GO:0008152;DNA metabolic process#GO:0006259;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;nucleobase-containing compound metabolic process#GO:0006139	catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	DNA metabolism protein#PC00009;DNA topoisomerase#PC00017	
ECOLI|EnsemblGenome=b3223|UniProtKB=P0A761	P0A761	nanE	PTHR36204:SF1	N-ACETYLMANNOSAMINE-6-PHOSPHATE 2-EPIMERASE-RELATED	N-ACETYLMANNOSAMINE-6-PHOSPHATE 2-EPIMERASE		carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;amino sugar catabolic process#GO:0046348;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b0955|UniProtKB=P75867	P75867	ycbZ	PTHR10046:SF49	ATP DEPENDENT LON PROTEASE FAMILY MEMBER	LON PROTEASE HOMOLOG-RELATED	catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233			serine protease#PC00203;protease#PC00190	
ECOLI|EnsemblGenome=b0030|UniProtKB=P22564	P22564	rihC	PTHR12304:SF15	INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE	NON-SPECIFIC RIBONUCLEOSIDE HYDROLASE RIHC	catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798	metabolic process#GO:0008152;purine-containing compound catabolic process#GO:0072523;purine nucleoside catabolic process#GO:0006152;nucleobase-containing small molecule metabolic process#GO:0055086;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;purine nucleoside metabolic process#GO:0042278;nucleoside catabolic process#GO:0009164;primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656;purine-containing compound metabolic process#GO:0072521;nucleoside metabolic process#GO:0009116;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	hydrolase#PC00121	
ECOLI|EnsemblGenome=b3521|UniProtKB=P37641	P37641	yhjC	PTHR30537:SF72	HTH-TYPE TRANSCRIPTIONAL REGULATOR	LYSR FAMILY TRANSCRIPTIONAL REGULATOR	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007		helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b3204|UniProtKB=P69829	P69829	ptsN	PTHR47738:SF1	PTS SYSTEM FRUCTOSE-LIKE EIIA COMPONENT-RELATED	NITROGEN REGULATORY PROTEIN	protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234				
ECOLI|EnsemblGenome=b4119|UniProtKB=P06720	P06720	melA	PTHR32092:SF6	6-PHOSPHO-BETA-GLUCOSIDASE-RELATED	ALPHA-GALACTOSIDASE	hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824		cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	glucosidase#PC00108;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3713|UniProtKB=P0AGE6	P0AGE6	chrR	PTHR30543:SF21	CHROMATE REDUCTASE	NAD(P)H-DEPENDENT FMN REDUCTASE LOT6	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;NAD(P)H dehydrogenase (quinone) activity#GO:0003955;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655	cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0222|UniProtKB=P63224	P63224	gmhA	PTHR30390:SF7	SEDOHEPTULOSE 7-PHOSPHATE ISOMERASE / DNAA INITIATOR-ASSOCIATING FACTOR FOR REPLICATION INITIATION	PHOSPHOHEPTOSE ISOMERASE	intramolecular phosphotransferase activity#GO:0016868;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853	carbohydrate derivative biosynthetic process#GO:1901137;organophosphate biosynthetic process#GO:0090407;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b3115|UniProtKB=P11868	P11868	tdcD	PTHR21060:SF17	ACETATE KINASE	PROPIONATE KINASE	catalytic activity#GO:0003824;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301	small molecule metabolic process#GO:0044281;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	transferase#PC00220;kinase#PC00137	
ECOLI|EnsemblGenome=b2469|UniProtKB=P27896	P27896	narQ	PTHR24421:SF10	NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED	NITRATE_NITRITE SENSOR PROTEIN NARQ	transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1056|UniProtKB=P0A8X2	P0A8X2	yceI	PTHR34406:SF1	PROTEIN YCEI	PROTEIN YCEI					
ECOLI|EnsemblGenome=b3192|UniProtKB=P0ADV7	P0ADV7	mlaC	PTHR36573:SF2	INTERMEMBRANE PHOSPHOLIPID TRANSPORT SYSTEM BINDING PROTEIN MLAC	INTERMEMBRANE PHOSPHOLIPID TRANSPORT SYSTEM BINDING PROTEIN MLAC		cellular process#GO:0009987;macromolecule localization#GO:0033036;cellular component organization#GO:0016043;intermembrane phospholipid transfer#GO:0120010;membrane organization#GO:0061024;phospholipid transport#GO:0015914;lipid transport#GO:0006869;organophosphate ester transport#GO:0015748;transport#GO:0006810;lipid localization#GO:0010876;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234	cell envelope#GO:0030313;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;periplasmic space#GO:0042597;extracellular region#GO:0005576		
ECOLI|EnsemblGenome=b1959|UniProtKB=P0AA70	P0AA70	yedA	PTHR32322:SF19	INNER MEMBRANE TRANSPORTER	EAMA DOMAIN-CONTAINING PROTEIN				transporter#PC00227	
ECOLI|EnsemblGenome=b3940|UniProtKB=P00562	P00562	metL	PTHR21499:SF29	ASPARTATE KINASE	BIFUNCTIONAL ASPARTOKINASE_HOMOSERINE DEHYDROGENASE 2	transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772	small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	kinase#PC00137;amino acid kinase#PC00045	
ECOLI|EnsemblGenome=b2079|UniProtKB=P69228	P69228	baeR	PTHR48111:SF4	REGULATOR OF RPOS	TRANSCRIPTIONAL REGULATORY PROTEIN BAER	double-stranded DNA binding#GO:0003690;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b2789|UniProtKB=Q46916	Q46916	gudP	PTHR11662:SF399	SOLUTE CARRIER FAMILY 17	MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN				secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b2927|UniProtKB=P0A9B6	P0A9B6	epd	PTHR43148:SF3	GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE 2	D-ERYTHROSE-4-PHOSPHATE DEHYDROGENASE	small molecule binding#GO:0036094;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;purine nucleotide binding#GO:0017076;nucleotide binding#GO:0000166;glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363	primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;glucose metabolic process#GO:0006006	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b3439|UniProtKB=P46852	P46852	yhhW	PTHR43212:SF4	QUERCETIN 2,3-DIOXYGENASE	QUERCETIN 2,3-DIOXYGENASE	dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824			oxygenase#PC00177;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0020|UniProtKB=P0A9G2	P0A9G2	nhaR	PTHR30293:SF2	TRANSCRIPTIONAL REGULATORY PROTEIN NAC-RELATED	TRANSCRIPTIONAL ACTIVATOR PROTEIN NHAR	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of DNA-templated transcription initiation#GO:2000142;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141		DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b3029|UniProtKB=P0ADU2	P0ADU2	ygiN	PTHR33336:SF16	QUINOL MONOOXYGENASE YGIN-RELATED	QUINOL MONOOXYGENASE YGIN-RELATED	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	response to stimulus#GO:0050896;response to abiotic stimulus#GO:0009628	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	oxygenase#PC00177	
ECOLI|EnsemblGenome=b1048|UniProtKB=P33136	P33136	mdoG	PTHR30504:SF4	GLUCANS BIOSYNTHESIS PROTEIN	GLUCANS BIOSYNTHESIS PROTEIN G		macromolecule metabolic process#GO:0043170;glucan biosynthetic process#GO:0009250;polysaccharide biosynthetic process#GO:0000271;metabolic process#GO:0008152;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;polysaccharide metabolic process#GO:0005976;beta-glucan biosynthetic process#GO:0051274;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;beta-glucan metabolic process#GO:0051273;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238	cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;extracellular region#GO:0005576;periplasmic space#GO:0042597		
ECOLI|EnsemblGenome=b0861|UniProtKB=P0AE30	P0AE30	artM	PTHR30614:SF10	MEMBRANE COMPONENT OF AMINO ACID ABC TRANSPORTER	ARGININE ABC TRANSPORTER PERMEASE PROTEIN ARTM	amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	transport#GO:0006810;amino acid transport#GO:0006865;establishment of localization#GO:0051234;localization#GO:0051179	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	amino acid transporter#PC00046	
ECOLI|EnsemblGenome=b3466|UniProtKB=P37614	P37614	yhhL	PTHR38775:SF1	INNER MEMBRANE PROTEIN-RELATED	MEMBRANE PROTEIN					
ECOLI|EnsemblGenome=b1793|UniProtKB=P64493	P64493	yoaF	PTHR38008:SF2	HEMOLYSIN-RELATED	DUF333 DOMAIN-CONTAINING PROTEIN					
ECOLI|EnsemblGenome=b3251|UniProtKB=P0A9X4	P0A9X4	mreB	PTHR42749:SF1	CELL SHAPE-DETERMINING PROTEIN MREB	CELL SHAPE-DETERMINING PROTEIN MREB		reproductive process#GO:0022414;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;reproductive process in single-celled organism#GO:0022413;cell division#GO:0051301;cellular process#GO:0009987;cell cycle process#GO:0022402;regulation of cell shape#GO:0008360;regulation of biological process#GO:0050789;cell cycle#GO:0007049;regulation of biological quality#GO:0065008;regulation of anatomical structure morphogenesis#GO:0022603;cytokinesis#GO:0000910;FtsZ-dependent cytokinesis#GO:0043093	intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856		
ECOLI|EnsemblGenome=b0589|UniProtKB=P23877	P23877	fepG	PTHR30472:SF24	FERRIC ENTEROBACTIN TRANSPORT SYSTEM PERMEASE PROTEIN	FERRIC ENTEROBACTIN TRANSPORT SYSTEM PERMEASE PROTEIN FEPG	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	siderophore-dependent iron import pathway#GO:0180060;cellular localization#GO:0051641;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;iron ion transport#GO:0006826;intracellular iron ion homeostasis#GO:0006879;metal ion transport#GO:0030001;homeostatic process#GO:0042592;iron import into cell#GO:0033212;intracellular monoatomic ion homeostasis#GO:0006873;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;iron coordination entity transport#GO:1901678;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;siderophore-iron import into cell#GO:0033214;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization in cell#GO:0051649	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b4511|UniProtKB=P18393	P18393	ybdZ	PTHR38444:SF1	ENTEROBACTIN BIOSYNTHESIS PROTEIN YBDZ	ENTEROBACTIN BIOSYNTHESIS PROTEIN YBDZ		siderophore metabolic process#GO:0009237;metabolic process#GO:0008152;secondary metabolite biosynthetic process#GO:0044550;peptide metabolic process#GO:0006518;secondary metabolic process#GO:0019748;cellular process#GO:0009987;siderophore biosynthetic process#GO:0019290;biosynthetic process#GO:0009058	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		
ECOLI|EnsemblGenome=b4470|UniProtKB=P42626	P42626	yhaM	PTHR30501:SF2	UPF0597 PROTEIN YHAM	UPF0597 PROTEIN YHAM	catalytic activity#GO:0003824;carbon-sulfur lyase activity#GO:0016846;lyase activity#GO:0016829	small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;carboxylic acid metabolic process#GO:0019752;sulfur compound catabolic process#GO:0044273;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152			
ECOLI|EnsemblGenome=b1725|UniProtKB=P77739	P77739	yniA	PTHR12149:SF13	FRUCTOSAMINE 3 KINASE-RELATED PROTEIN	KETOAMINE KINASE YNIA-RELATED	kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824			transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137	
ECOLI|Gene_OrderedLocusName=JW0258|UniProtKB=Q79E92	Q79E92	ykgN	PTHR33215:SF13	PROTEIN DISTAL ANTENNA	PROTEIN DISTAL ANTENNA					
ECOLI|EnsemblGenome=b0692|UniProtKB=P0AAF1	P0AAF1	potE	PTHR42770:SF6	AMINO ACID TRANSPORTER-RELATED	PUTRESCINE TRANSPORTER POTE	carboxylic acid transmembrane transporter activity#GO:0046943;polyamine transmembrane transporter activity#GO:0015203;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804;L-amino acid transmembrane transporter activity#GO:0015179		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	amino acid transporter#PC00046;secondary carrier transporter#PC00258;transporter#PC00227	
ECOLI|EnsemblGenome=b3281|UniProtKB=P15770	P15770	aroE	PTHR21089:SF1	SHIKIMATE DEHYDROGENASE	BIFUNCTIONAL 3-DEHYDROQUINATE DEHYDRATASE_SHIKIMATE DEHYDROGENASE, CHLOROPLASTIC	catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058		dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	Chorismate biosynthesis#P02734>Shikimate dehydrogenase#P02873
ECOLI|EnsemblGenome=b2699|UniProtKB=P0A7G6	P0A7G6	recA	PTHR45900:SF1	RECA	MITOCHONDRIAL DNA REPAIR PROTEIN RECA HOMOLOG-RELATED	catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;DNA endonuclease activity#GO:0004520;DNA binding#GO:0003677;nuclease activity#GO:0004518	nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;metabolic process#GO:0008152;recombinational repair#GO:0000725;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170	DNA polymerase complex#GO:0042575;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535	DNA strand-pairing protein#PC00016	
ECOLI|EnsemblGenome=b0231|UniProtKB=Q47155	Q47155	dinB	PTHR11076:SF36	DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER	DNA POLYMERASE IV	DNA-directed DNA polymerase activity#GO:0003887;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772	macromolecule metabolic process#GO:0043170;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;SOS response#GO:0009432;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;DNA synthesis involved in DNA replication#GO:0090592;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304		DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b4313|UniProtKB=P0ADH7	P0ADH7	fimE	PTHR30349:SF62	PHAGE INTEGRASE-RELATED	TYPE 1 FIMBRIAE REGULATORY PROTEIN FIMB-RELATED	catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824	macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;chromosome segregation#GO:0007059;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238		viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b2453|UniProtKB=P76553	P76553	eutG	PTHR11496:SF94	ALCOHOL DEHYDROGENASE	ALCOHOL DEHYDROGENASE EUTG-RELATED	oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824			dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b1818|UniProtKB=P69801	P69801	manY	PTHR32502:SF4	N-ACETYLGALACTOSAMINE PERMEASE II COMPONENT-RELATED	PTS SYSTEM MANNOSE-SPECIFIC EIIC COMPONENT	carbohydrate transmembrane transporter activity#GO:0015144;phosphotransferase activity, alcohol group as acceptor#GO:0016773;active transmembrane transporter activity#GO:0022804;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740	import across plasma membrane#GO:0098739;carbohydrate transmembrane transport#GO:0034219;cellular process#GO:0009987;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;carbohydrate transport#GO:0008643;transport#GO:0006810	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b2615|UniProtKB=P0A7B3	P0A7B3	nadK	PTHR20275:SF46	NAD KINASE	NAD KINASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773	small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;pyridine-containing compound metabolic process#GO:0072524;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;NADP+ metabolic process#GO:0006739;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	nucleotide kinase#PC00172	
ECOLI|EnsemblGenome=b3794|UniProtKB=P27836	P27836	wecG	PTHR34136:SF1	UDP-N-ACETYL-D-MANNOSAMINURONIC ACID TRANSFERASE	UDP-N-ACETYL-D-MANNOSAMINURONIC ACID TRANSFERASE	glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740				
ECOLI|EnsemblGenome=b1093|UniProtKB=P0AEK2	P0AEK2	fabG	PTHR42760:SF96	SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER	3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616	monocarboxylic acid biosynthetic process#GO:0072330;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987		oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1657|UniProtKB=P77389	P77389	ydhP	PTHR43124:SF8	PURINE EFFLUX PUMP PBUE	INNER MEMBRANE TRANSPORT PROTEIN YDHP	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b2617|UniProtKB=P0A937	P0A937	bamE	PTHR37482:SF1	OUTER MEMBRANE PROTEIN ASSEMBLY FACTOR BAME	OUTER MEMBRANE PROTEIN ASSEMBLY FACTOR BAME	molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674	cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein insertion into membrane#GO:0051205;cellular component assembly#GO:0022607;membrane organization#GO:0061024;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;membrane assembly#GO:0071709	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;membrane#GO:0016020;cell outer membrane#GO:0009279;external encapsulating structure#GO:0030312;membrane protein complex#GO:0098796;side of membrane#GO:0098552;outer membrane#GO:0019867;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392	chaperone#PC00072	
ECOLI|EnsemblGenome=b2142|UniProtKB=P0AD19	P0AD19	yohK	PTHR30249:SF0	PUTATIVE SEROTONIN TRANSPORTER	PLASTIDAL GLYCOLATE_GLYCERATE TRANSLOCATOR 1, CHLOROPLASTIC				transporter#PC00227	
ECOLI|EnsemblGenome=b3788|UniProtKB=P27830	P27830	rffG	PTHR43000:SF47	DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED	DTDP-GLUCOSE 4,6-DEHYDRATASE 2	catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829			dehydratase#PC00091	
ECOLI|EnsemblGenome=b0032|UniProtKB=P0A6F1	P0A6F1	carA	PTHR11405:SF4	CARBAMOYLTRANSFERASE FAMILY MEMBER	CARBAMOYL PHOSPHATE SYNTHASE ARGININE-SPECIFIC SMALL CHAIN	ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879	carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;L-arginine biosynthetic process#GO:0006526;proteinogenic amino acid biosynthetic process#GO:0170038	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494	metabolite interconversion enzyme#PC00262;ligase#PC00142	De novo pyrimidine ribonucleotides biosythesis#P02740>Carbamoyl phosphate synthetase#P02925
ECOLI|EnsemblGenome=b3575|UniProtKB=P37672	P37672	dlgD	PTHR11091:SF3	OXIDOREDUCTASE-RELATED	2,3-DIKETO-L-GULONATE REDUCTASE				metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b4227|UniProtKB=P39325	P39325	ytfQ	PTHR46847:SF3	D-ALLOSE-BINDING PERIPLASMIC PROTEIN-RELATED	GALACTOFURANOSE-BINDING PROTEIN YTFQ	binding#GO:0005488;small molecule binding#GO:0036094;monosaccharide binding#GO:0048029;carbohydrate binding#GO:0030246	carbohydrate transport#GO:0008643;cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;carbohydrate transmembrane transport#GO:0034219;establishment of localization#GO:0051234	cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;extracellular region#GO:0005576;periplasmic space#GO:0042597		
ECOLI|EnsemblGenome=b3085|UniProtKB=P42597	P42597	ygjP	PTHR30399:SF2	UNCHARACTERIZED PROTEIN YGJP	UTP PYROPHOSPHATASE					
ECOLI|EnsemblGenome=b0860|UniProtKB=P30860	P30860	artJ	PTHR35936:SF36	MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE F	ABC TRANSPORTER ARGININE-BINDING PROTEIN 1	amino acid binding#GO:0016597;binding#GO:0005488		periplasmic space#GO:0042597;extracellular region#GO:0005576;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313		
ECOLI|EnsemblGenome=b1395|UniProtKB=P76083	P76083	paaH	PTHR48075:SF13	3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN	3-HYDROXYADIPYL-COA DEHYDROGENASE	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491	lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395		oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b4074|UniProtKB=P32710	P32710	nrfE	PTHR43653:SF3	CYTOCHROME C ASSEMBLY PROTEIN-RELATED	CYTOCHROME C-TYPE BIOGENESIS PROTEIN NRFE-RELATED			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	chaperone#PC00072	
ECOLI|EnsemblGenome=b2741|UniProtKB=P13445	P13445	rpoS	PTHR30603:SF67	RNA POLYMERASE SIGMA FACTOR RPO	RNA POLYMERASE SIGMA FACTOR RPOS	sequence-specific double-stranded DNA binding#GO:1990837;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;catalytic activity, acting on RNA#GO:0140098;sequence-specific DNA binding#GO:0043565;transferase activity#GO:0016740;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110	regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468	transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991	helix-turn-helix transcription factor#PC00116;Sigma factor#PC00267	
ECOLI|EnsemblGenome=b2233|UniProtKB=P45508	P45508	yfaL	PTHR12338:SF5	AUTOTRANSPORTER	ANTIGEN 43-RELATED				protease#PC00190	
ECOLI|EnsemblGenome=b1922|UniProtKB=P0AEM6	P0AEM6	fliA	PTHR30385:SF7	SIGMA FACTOR F  FLAGELLAR	RNA POLYMERASE SIGMA FACTOR FLIA	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007		DNA-binding transcription factor#PC00218;Sigma factor#PC00267	
ECOLI|EnsemblGenome=b0870|UniProtKB=P75823	P75823	ltaE	PTHR48097:SF9	L-THREONINE ALDOLASE-RELATED	L-THREONINE ALDOLASE	catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832	small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	aldolase#PC00044;lyase#PC00144	
ECOLI|EnsemblGenome=b2769|UniProtKB=Q46907	Q46907	ygcQ	PTHR43153:SF5	ELECTRON TRANSFER FLAVOPROTEIN ALPHA	PROTEIN FIXB-RELATED	nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168	lipid modification#GO:0030258;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238		oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1214|UniProtKB=P0AGM5	P0AGM5	ychA	PTHR31350:SF21	SI:DKEY-261L7.2	F-BOX ONLY PROTEIN 21					
ECOLI|EnsemblGenome=b0785|UniProtKB=P30749	P30749	moaE	PTHR23404:SF2	MOLYBDOPTERIN SYNTHASE RELATED	MOLYBDOPTERIN SYNTHASE CATALYTIC SUBUNIT			cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165		
ECOLI|Gene_OrderedLocusName=JW4227|UniProtKB=P39347	P39347	intB	PTHR30629:SF9	PROPHAGE INTEGRASE	PROTEIN INTB-RELATED	catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097				
ECOLI|EnsemblGenome=b3091|UniProtKB=P42604	P42604	uxaA	PTHR30536:SF6	ALTRONATE/GALACTARATE DEHYDRATASE	ALTRONATE DEHYDRATASE	catalytic activity#GO:0003824;lyase activity#GO:0016829	small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid catabolic process#GO:0072329;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;monosaccharide metabolic process#GO:0005996		dehydratase#PC00091	
ECOLI|EnsemblGenome=b3749|UniProtKB=P04983	P04983	rbsA	PTHR43790:SF10	CARBOHYDRATE TRANSPORT ATP-BINDING PROTEIN MG119-RELATED	D-ALLOSE IMPORT ATP-BINDING PROTEIN ALSA-RELATED	sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b0445|UniProtKB=P46890	P46890	ybaE	PTHR30290:SF19	PERIPLASMIC BINDING COMPONENT OF ABC TRANSPORTER	ABC TRANSPORTER PERIPLASMIC BINDING PROTEIN	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	peptide transport#GO:0015833;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179		transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b1434|UniProtKB=P77626	P77626	sutR	PTHR46797:SF26	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR SUTR	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222		Lambda repressor-like transcription factor#PC00245	
ECOLI|EnsemblGenome=b1859|UniProtKB=P39832	P39832	znuB	PTHR30477:SF23	ABC-TRANSPORTER METAL-BINDING PROTEIN	HIGH-AFFINITY ZINC UPTAKE SYSTEM MEMBRANE PROTEIN ZNUB	monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0776|UniProtKB=P12998	P12998	bioF	PTHR13693:SF100	CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE	8-AMINO-7-OXONONANOATE SYNTHASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747	small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;biotin metabolic process#GO:0006768;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;monocarboxylic acid metabolic process#GO:0032787;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281		transaminase#PC00216	Biotin biosynthesis#P02731>8-Amino-7-oxononanoate synthase#P02858
ECOLI|EnsemblGenome=b2568|UniProtKB=P00803	P00803	lepB	PTHR43390:SF17	SIGNAL PEPTIDASE I	SIGNAL PEPTIDASE I	catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787	macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203	
ECOLI|EnsemblGenome=b1821|UniProtKB=P76264	P76264	mntP	PTHR35529:SF1	MANGANESE EFFLUX PUMP MNTP-RELATED	MANGANESE EXPORTER MNTP	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transition metal ion transmembrane transporter activity#GO:0046915;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075	inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;intracellular monoatomic ion homeostasis#GO:0006873;export from cell#GO:0140352;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b2010|UniProtKB=P33013	P33013	dacD	PTHR21581:SF5	D-ALANYL-D-ALANINE CARBOXYPEPTIDASE	D-ALANYL-D-ALANINE CARBOXYPEPTIDASE DACD				serine protease#PC00203;protease#PC00190	
ECOLI|EnsemblGenome=b2165|UniProtKB=P33025	P33025	psuG	PTHR42909:SF1	ZGC:136858	CARBOHYDRATE KINASE PFKB DOMAIN-CONTAINING PROTEIN	lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824		cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0198|UniProtKB=P31547	P31547	metI	PTHR30450:SF8	ABC TRANSPORTER PERMEASE	D-METHIONINE TRANSPORT SYSTEM PERMEASE PROTEIN METI		cellular process#GO:0009987;nitrogen compound transport#GO:0071705;carboxylic acid transmembrane transport#GO:1905039;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b2442|UniProtKB=P76542	P76542	intZ	PTHR30629:SF2	PROPHAGE INTEGRASE	PROPHAGE INTEGRASE INTS-RELATED					
ECOLI|EnsemblGenome=b2581|UniProtKB=P0AGJ5	P0AGJ5	yfiF	PTHR46429:SF2	23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB	TRNA_RRNA METHYLTRANSFERASE					
ECOLI|EnsemblGenome=b2531|UniProtKB=P0AGK8	P0AGK8	iscR	PTHR33221:SF5	WINGED HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, RRF2 FAMILY	HTH-TYPE TRANSCRIPTIONAL REGULATOR ISCR	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b4711|UniProtKB=A0A385XJE6	A0A385XJE6	insH21	PTHR35604:SF2	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824	nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b3356|UniProtKB=P0ADX1	P0ADX1	yhfA	PTHR34352:SF1	PROTEIN YHFA	PROTEIN YHFA					
ECOLI|EnsemblGenome=b3209|UniProtKB=P0ABU5	P0ABU5	elbB	PTHR10224:SF12	ES1 PROTEIN HOMOLOG, MITOCHONDRIAL	GLYOXALASE ELBB					
ECOLI|EnsemblGenome=b2364|UniProtKB=P46068	P46068	dsdC	PTHR30537:SF32	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR DSDC	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789		helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b1874|UniProtKB=P67826	P67826	cutC	PTHR12598:SF0	COPPER HOMEOSTASIS PROTEIN CUTC	COPPER HOMEOSTASIS PROTEIN CUTC HOMOLOG	metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;copper ion binding#GO:0005507;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914			primary active transporter#PC00068	
ECOLI|EnsemblGenome=b0259|UniProtKB=P0CE49	P0CE49	insH1	PTHR35604:SF2	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640	macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b1881|UniProtKB=P0A9H9	P0A9H9	cheZ	PTHR43693:SF1	PROTEIN PHOSPHATASE CHEZ	PROTEIN PHOSPHATASE CHEZ	hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788	chemotaxis#GO:0006935;response to chemical#GO:0042221;taxis#GO:0042330;response to stimulus#GO:0050896;response to external stimulus#GO:0009605;locomotion#GO:0040011		protein modifying enzyme#PC00260;protein phosphatase#PC00195	
ECOLI|EnsemblGenome=b2832|UniProtKB=P67127	P67127	ygdQ	PTHR30060:SF1	INNER MEMBRANE PROTEIN	UPF0053 INNER MEMBRANE PROTEIN YGDQ			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b4544|UniProtKB=Q47377	Q47377	arnE	PTHR30561:SF23	SMR FAMILY PROTON-DEPENDENT DRUG EFFLUX TRANSPORTER SUGE	4-AMINO-4-DEOXY-L-ARABINOSE-PHOSPHOUNDECAPRENOL FLIPPASE SUBUNIT ARNE-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate derivative transmembrane transporter activity#GO:1901505	transport#GO:0006810;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b0303|UniProtKB=P75687	P75687	rclB	PTHR34156:SF3	OUTER MEMBRANE PROTEIN-RELATED-RELATED	PERIPLASMIC PROTEIN		response to stimulus#GO:0050896;response to stress#GO:0006950			
ECOLI|EnsemblGenome=b2141|UniProtKB=P60632	P60632	yohJ	PTHR33931:SF5	HOLIN-LIKE PROTEIN CIDA-RELATED	UPF0299 MEMBRANE PROTEIN YOHJ					
ECOLI|EnsemblGenome=b0093|UniProtKB=P06136	P06136	ftsQ	PTHR35851:SF1	CELL DIVISION PROTEIN FTSQ	CELL DIVISION PROTEIN FTSQ		cell division#GO:0051301;cellular process#GO:0009987;cell cycle process#GO:0022402;cellular component biogenesis#GO:0044085;cell septum assembly#GO:0090529;cell cycle#GO:0007049;cellular component organization#GO:0016043;reproductive process#GO:0022414;cellular component assembly#GO:0022607;reproductive process in single-celled organism#GO:0022413;cytokinetic process#GO:0032506;cytokinesis#GO:0000910;FtsZ-dependent cytokinesis#GO:0043093;division septum assembly#GO:0000917;cellular component organization or biogenesis#GO:0071840	cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell septum#GO:0030428;cell division site#GO:0032153;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b4133|UniProtKB=P23890	P23890	cadC	PTHR48111:SF23	REGULATOR OF RPOS	TRANSCRIPTIONAL ACTIVATOR CADC	sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;molecular transducer activity#GO:0060089	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b3128|UniProtKB=P39829	P39829	garD	PTHR30536:SF1	ALTRONATE/GALACTARATE DEHYDRATASE	GALACTARATE DEHYDRATASE (L-THREO-FORMING)	catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836	cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052		dehydratase#PC00091	
ECOLI|EnsemblGenome=b2251|UniProtKB=P52006	P52006	nudI	PTHR43758:SF9	7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE	NUCLEOSIDE TRIPHOSPHATASE NUDI	catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787		intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	phosphatase#PC00181;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3579|UniProtKB=P37676	P37676	yiaO	PTHR33376:SF18	SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP-RELATED	2,3-DIKETO-L-GULONATE-BINDING PERIPLASMIC PROTEIN YIAO	carbohydrate binding#GO:0030246;binding#GO:0005488				
ECOLI|EnsemblGenome=b2014|UniProtKB=P0AA47	P0AA47	plaP	PTHR42770:SF1	AMINO ACID TRANSPORTER-RELATED	LOW-AFFINITY PUTRESCINE IMPORTER PLAP	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227;amino acid transporter#PC00046;secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b4058|UniProtKB=P0A698	P0A698	uvrA	PTHR43152:SF3	UVRABC SYSTEM PROTEIN A	UVRABC SYSTEM PROTEIN A	nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677	response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;DNA damage response#GO:0006974;cellular response to stress#GO:0033554	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227	
ECOLI|EnsemblGenome=b3993|UniProtKB=P30137	P30137	thiE	PTHR20857:SF15	THIAMINE-PHOSPHATE PYROPHOSPHORYLASE	THIAMINE BIOSYNTHETIC BIFUNCTIONAL ENZYME	transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824	small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;alcohol biosynthetic process#GO:0046165;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	transferase#PC00220	Thiamin biosynthesis#P02779>Thiamin phosphate synthase#P03173
ECOLI|EnsemblGenome=b3471|UniProtKB=P37619	P37619	yhhQ	PTHR34300:SF1	QUEUOSINE PRECURSOR TRANSPORTER-RELATED	QUEUOSINE PRECURSOR TRANSPORTER		cellular process#GO:0009987;transport#GO:0006810;nitrogen compound transport#GO:0071705;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b1778|UniProtKB=P0A746	P0A746	msrB	PTHR10173:SF52	METHIONINE SULFOXIDE REDUCTASE	METHIONINE-R-SULFOXIDE REDUCTASE B1	catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491		cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	oxidoreductase#PC00176;reductase#PC00198;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2709|UniProtKB=P37013	P37013	norR	PTHR32071:SF35	TRANSCRIPTIONAL REGULATORY PROTEIN	ANAEROBIC NITRIC OXIDE REDUCTASE TRANSCRIPTION REGULATOR NORR	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110	positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889	protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991	DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b2740|UniProtKB=Q46892	Q46892	ygbN	PTHR30354:SF25	GNT FAMILY GLUCONATE TRANSPORTER	INNER MEMBRANE PERMEASE YGBN	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	secondary carrier transporter#PC00258;transporter#PC00227	
ECOLI|EnsemblGenome=b2234|UniProtKB=P00452	P00452	nrdA	PTHR11573:SF6	RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN	RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT	nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;oxidoreductase activity#GO:0016491;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;catalytic activity#GO:0003824;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;ATP binding#GO:0005524;small molecule binding#GO:0036094	cellular process#GO:0009987;metabolic process#GO:0008152;biosynthetic process#GO:0009058	cytosol#GO:0005829;oxidoreductase complex#GO:1990204;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	reductase#PC00198;oxidoreductase#PC00176	De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo purine biosynthesis#P02738>GDP reductase#P02909;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921
ECOLI|EnsemblGenome=b2515|UniProtKB=P62620	P62620	ispG	PTHR30454:SF1	4-HYDROXY-3-METHYLBUT-2-EN-1-YL DIPHOSPHATE SYNTHASE	4-HYDROXY-3-METHYLBUT-2-EN-1-YL DIPHOSPHATE SYNTHASE (FLAVODOXIN)	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	carbohydrate derivative metabolic process#GO:1901135;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glyceraldehyde-3-phosphate metabolic process#GO:0019682;isoprenoid biosynthetic process#GO:0008299;organophosphate biosynthetic process#GO:0090407;isoprenoid metabolic process#GO:0006720	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		
ECOLI|EnsemblGenome=b2559|UniProtKB=P68398	P68398	tadA	PTHR11079:SF202	CYTOSINE DEAMINASE FAMILY MEMBER	TRNA-SPECIFIC ADENOSINE DEAMINASE	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;adenosine deaminase activity#GO:0004000;catalytic activity, acting on a tRNA#GO:0140101;tRNA-specific adenosine deaminase activity#GO:0008251	biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;adenosine to inosine editing#GO:0006382;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble base modification#GO:0002097;base conversion or substitution editing#GO:0016553;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187		deaminase#PC00088;metabolite interconversion enzyme#PC00262;hydrolase#PC00121	Salvage pyrimidine ribonucleotides#P02775>Cytosine deaminase#P03155;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCTP deaminase#P02920;Salvage pyrimidine deoxyribonucleotides#P02774>Cytidine deaminase#P03144;Salvage pyrimidine ribonucleotides#P02775>Cytidine deaminase#P03154
ECOLI|EnsemblGenome=b2977|UniProtKB=P0AEQ1	P0AEQ1	glcG	PTHR34309:SF1	SLR1406 PROTEIN	PROTEIN GLCG					
ECOLI|EnsemblGenome=b3053|UniProtKB=P30870	P30870	glnE	PTHR30621:SF0	GLUTAMINE SYNTHETASE ADENYLYLTRANSFERASE	BIFUNCTIONAL GLUTAMINE SYNTHETASE ADENYLYLTRANSFERASE_ADENYLYL-REMOVING ENZYME	catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566	regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;nucleotidyltransferase#PC00174	
ECOLI|EnsemblGenome=b0262|UniProtKB=P37009	P37009	fbpC	PTHR24220:SF697	IMPORT ATP-BINDING PROTEIN	FE(3+) IONS IMPORT ATP-BINDING PROTEIN FBPC	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b2407|UniProtKB=P45563	P45563	xapA	PTHR11904:SF9	METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE	PURINE NUCLEOSIDE PHOSPHORYLASE-RELATED	glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763	nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;purine-containing compound catabolic process#GO:0072523;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleotide biosynthetic process#GO:0009165;nucleoside catabolic process#GO:0009164;nucleotide metabolic process#GO:0009117;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule catabolic process#GO:0034656;phosphorus metabolic process#GO:0006793;nucleoside phosphate biosynthetic process#GO:1901293;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;glycosyl compound catabolic process#GO:1901658;organophosphate biosynthetic process#GO:0090407;pyridine-containing compound metabolic process#GO:0072524;purine nucleoside metabolic process#GO:0042278;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;nucleoside metabolic process#GO:0009116;primary metabolic process#GO:0044238	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	kinase#PC00137;nucleotide kinase#PC00172	Adenine and hypoxanthine salvage pathway#P02723>Inosine phosphorylase#P02813;Xanthine and guanine salvage pathway#P02788>Deoxyguanosine phosphorylase#P03248;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine phosphorylase#P02808;Adenine and hypoxanthine salvage pathway#P02723>Deoxyinosine phosphorylase#P02812;Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphorylase#P02805;Xanthine and guanine salvage pathway#P02788>Guanosine phosphorylase#P03250
ECOLI|EnsemblGenome=b0489|UniProtKB=P0AA53	P0AA53	qmcA	PTHR43327:SF10	STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL	STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL				transporter#PC00227	
ECOLI|EnsemblGenome=b1045|UniProtKB=P0A8D6	P0A8D6	ymdB	PTHR11106:SF125	GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED	O-ACETYL-ADP-RIBOSE DEACETYLASE	deacetylase activity#GO:0019213;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;deacylase activity#GO:0160215;catalytic activity#GO:0003824				
ECOLI|EnsemblGenome=b0612|UniProtKB=P0AE74	P0AE74	citT	PTHR42826:SF2	DICARBOXYLATE TRANSPORTER 2.1, CHLOROPLASTIC	CITRATE_SUCCINATE ANTIPORTER-RELATED			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	primary active transporter#PC00068;transporter#PC00227	
ECOLI|EnsemblGenome=b0661|UniProtKB=P0AEI1	P0AEI1	miaB	PTHR43020:SF3	CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 1	TRNA-2-METHYLTHIO-N(6)-DIMETHYLALLYLADENOSINE SYNTHASE	iron-sulfur cluster binding#GO:0051536;catalytic activity, acting on a tRNA#GO:0140101;transferase activity, transferring sulphur-containing groups#GO:0016782;small molecule binding#GO:0036094;binding#GO:0005488;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824	primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1855|UniProtKB=P24205	P24205	lpxM	PTHR30606:SF4	LIPID A BIOSYNTHESIS LAUROYL ACYLTRANSFERASE	LIPID A BIOSYNTHESIS MYRISTOYLTRANSFERASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746	metabolic process#GO:0008152;lipid metabolic process#GO:0006629;carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;biosynthetic process#GO:0009058	membrane#GO:0016020;cellular anatomical structure#GO:0110165	acyltransferase#PC00042;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3058|UniProtKB=P0AC16	P0AC16	folB	PTHR42844:SF1	DIHYDRONEOPTERIN ALDOLASE 1-RELATED	DIHYDRONEOPTERIN ALDOLASE 1-RELATED	catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832		cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	aldolase#PC00044;metabolite interconversion enzyme#PC00262	Tetrahydrofolate biosynthesis#P02742>Dihydroneopterin aldolase#P02941
ECOLI|EnsemblGenome=b3473|UniProtKB=P37621	P37621	yhhS	PTHR23517:SF13	RESISTANCE PROTEIN MDTM, PUTATIVE-RELATED-RELATED	MAJOR FACILITATOR SUPERFAMILY MFS_1			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b0810|UniProtKB=P0AEQ6	P0AEQ6	glnP	PTHR30614:SF50	MEMBRANE COMPONENT OF AMINO ACID ABC TRANSPORTER	GLUTAMINE TRANSPORT SYSTEM PERMEASE PROTEIN GLNP	amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;neutral L-amino acid transmembrane transporter activity#GO:0015175;L-amino acid transmembrane transporter activity#GO:0015179	neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234;localization#GO:0051179;organic acid transport#GO:0015849;transport#GO:0006810;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	amino acid transporter#PC00046	
ECOLI|EnsemblGenome=b3161|UniProtKB=P0AAD2	P0AAD2	mtr	PTHR46997:SF1	LOW AFFINITY TRYPTOPHAN PERMEASE-RELATED	LOW AFFINITY TRYPTOPHAN PERMEASE-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	transport#GO:0006810;amino acid transport#GO:0006865;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b1089|UniProtKB=P0A7N4	P0A7N4	rpmF	PTHR35534:SF1	50S RIBOSOMAL PROTEIN L32	LARGE RIBOSOMAL SUBUNIT PROTEIN BL32	structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198		intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829	translational protein#PC00263;ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b1774|UniProtKB=P77280	P77280	ydjJ	PTHR43161:SF9	SORBITOL DEHYDROGENASE	GLUCOSE 1-DEHYDROGENASE 1				dehydrogenase#PC00092;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0031|UniProtKB=P04036	P04036	dapB	PTHR20836:SF9	DIHYDRODIPICOLINATE REDUCTASE	4-HYDROXY-TETRAHYDRODIPICOLINATE REDUCTASE	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176	Lysine biosynthesis#P02751>Dihydrodipicolinate  reductase#P03006
ECOLI|EnsemblGenome=b2366|UniProtKB=P00926	P00926	dsdA	PTHR48078:SF9	THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED	D-SERINE DEHYDRATASE	catalytic activity#GO:0003824;lyase activity#GO:0016829	cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152		lyase#PC00144;dehydratase#PC00091	
ECOLI|EnsemblGenome=b2925|UniProtKB=P0AB71	P0AB71	fbaA	PTHR30559:SF0	FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 2	FRUCTOSE-BISPHOSPHATE ALDOLASE	fructose-bisphosphate aldolase activity#GO:0004332;catalytic activity#GO:0003824;zinc ion binding#GO:0008270;carbon-carbon lyase activity#GO:0016830;metal ion binding#GO:0046872;lyase activity#GO:0016829;cation binding#GO:0043169;aldehyde-lyase activity#GO:0016832;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914	purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate biosynthetic process#GO:0016051;ADP catabolic process#GO:0046032;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate catabolic process#GO:1901292;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;ribonucleoside diphosphate metabolic process#GO:0009185;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;gluconeogenesis#GO:0006094;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;hexose biosynthetic process#GO:0019319;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;cellular respiration#GO:0045333;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;small molecule biosynthetic process#GO:0044283;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;aldolase#PC00044	
ECOLI|EnsemblGenome=b4346|UniProtKB=P15005	P15005	mcrB	PTHR37291:SF1	5-METHYLCYTOSINE-SPECIFIC RESTRICTION ENZYME B	TYPE IV METHYL-DIRECTED RESTRICTION ENZYME ECOKMCRB SUBUNIT					
ECOLI|EnsemblGenome=b2966|UniProtKB=Q46831	Q46831	yqgA	PTHR36111:SF2	INNER MEMBRANE PROTEIN-RELATED	DUF554 DOMAIN-CONTAINING PROTEIN			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b2808|UniProtKB=P0A9F6	P0A9F6	gcvA	PTHR30537:SF26	HTH-TYPE TRANSCRIPTIONAL REGULATOR	GLYCINE CLEAVAGE SYSTEM TRANSCRIPTIONAL ACTIVATOR	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468		helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b0909|UniProtKB=P43674	P43674	ycaL	PTHR22726:SF8	METALLOENDOPEPTIDASE OMA1	METALLOPROTEASE YCAL	metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787	primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538	membrane#GO:0016020;cellular anatomical structure#GO:0110165	protease#PC00190;protein modifying enzyme#PC00260;metalloprotease#PC00153	
ECOLI|EnsemblGenome=b0433|UniProtKB=P0AE16	P0AE16	ampG	PTHR12778:SF10	SOLUTE CARRIER FAMILY 33  ACETYL-COA TRANSPORTER -RELATED	SOLUTE CARRIER FAMILY 33 MEMBER 2	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		membrane#GO:0016020;cellular anatomical structure#GO:0110165	transporter#PC00227;secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b4004|UniProtKB=P14375	P14375	zraR	PTHR32071:SF117	TRANSCRIPTIONAL REGULATORY PROTEIN	PTS-DEPENDENT DIHYDROXYACETONE KINASE OPERON REGULATORY PROTEIN-RELATED	sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription activator activity#GO:0001216;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677	regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556	protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993	DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b3076|UniProtKB=P06864	P06864	ebgA	PTHR46323:SF2	BETA-GALACTOSIDASE	BETA-GALACTOSIDASE	hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553	primary metabolic process#GO:0044238;cellular process#GO:0009987;oligosaccharide catabolic process#GO:0009313;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052;oligosaccharide metabolic process#GO:0009311	protein-containing complex#GO:0032991;catalytic complex#GO:1902494	metabolite interconversion enzyme#PC00262;galactosidase#PC00104;hydrolase#PC00121	
ECOLI|EnsemblGenome=b1068|UniProtKB=P75931	P75931	yceM	PTHR43708:SF4	CONSERVED EXPRESSED OXIDOREDUCTASE (EUROFUNG)	OXIDOREDUCTASE YCEM-RELATED				oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1377|UniProtKB=P77747	P77747	ompN	PTHR34501:SF8	PROTEIN YDDL-RELATED	OUTER MEMBRANE PORIN N-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829		protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane protein complex#GO:0098796		
ECOLI|EnsemblGenome=b1943|UniProtKB=P52614	P52614	fliK	PTHR37533:SF2	FLAGELLAR HOOK-LENGTH CONTROL PROTEIN	FLAGELLAR HOOK-LENGTH CONTROL PROTEIN		cellular process#GO:0009987;cilium or flagellum-dependent cell motility#GO:0001539;archaeal or bacterial-type flagellum-dependent cell motility#GO:0097588;cell motility#GO:0048870;bacterial-type flagellum-dependent cell motility#GO:0071973	membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;bacterial-type flagellum#GO:0009288;cell projection#GO:0042995		
ECOLI|EnsemblGenome=b0913|UniProtKB=P37443	P37443	ycaI	PTHR30619:SF1	DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2	RECOMBINATION PROTEIN 2			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b4235|UniProtKB=P0AFK0	P0AFK0	pmbA	PTHR43421:SF1	METALLOPROTEASE PMBA	METALLOPROTEASE PMBA		protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;cytosol#GO:0005829	protein modifying enzyme#PC00260;protease#PC00190	
ECOLI|EnsemblGenome=b4485|UniProtKB=Q6BEX0	Q6BEX0	ytfR	PTHR43790:SF9	CARBOHYDRATE TRANSPORT ATP-BINDING PROTEIN MG119-RELATED	GALACTOFURANOSE TRANSPORTER ATP-BINDING PROTEIN YTFR	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b3886|UniProtKB=P0A8K8	P0A8K8	yihY	PTHR30213:SF0	INNER MEMBRANE PROTEIN YHJD	UPF0761 MEMBRANE PROTEIN YIHY			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b3307|UniProtKB=P0AG59	P0AG59	rpsN	PTHR19836:SF32	30S RIBOSOMAL PROTEIN S14	SMALL RIBOSOMAL SUBUNIT PROTEIN US14	structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735	translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467	intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829	ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b0239|UniProtKB=P04335	P04335	frsA	PTHR22946:SF4	DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED	ESTERASE FRSA	catalytic activity#GO:0003824;hydrolase activity#GO:0016787				
ECOLI|EnsemblGenome=b1632|UniProtKB=P77179	P77179	rsxE	PTHR30586:SF0	ELECTRON TRANSPORT COMPLEX PROTEIN RNFE	ION-TRANSLOCATING OXIDOREDUCTASE COMPLEX SUBUNIT E			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b3317|UniProtKB=P60422	P60422	rplB	PTHR13691:SF5	RIBOSOMAL PROTEIN L2	LARGE RIBOSOMAL SUBUNIT PROTEIN UL2CZ_UL2CY	structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198	protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229	ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b0935|UniProtKB=P80645	P80645	ssuD	PTHR42847:SF4	ALKANESULFONATE MONOOXYGENASE	ALKANESULFONATE MONOOXYGENASE-RELATED	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705	sulfur compound catabolic process#GO:0044273;catabolic process#GO:0009056;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987		oxygenase#PC00177	
ECOLI|EnsemblGenome=b0186|UniProtKB=P52095	P52095	ldcC	PTHR43643:SF5	HISTIDINOL-PHOSPHATE AMINOTRANSFERASE 2	CONSTITUTIVE LYSINE DECARBOXYLASE				metabolite interconversion enzyme#PC00262;transaminase#PC00216	
ECOLI|EnsemblGenome=b1129|UniProtKB=P23837	P23837	phoQ	PTHR45436:SF4	SENSOR HISTIDINE KINASE YKOH	SENSOR PROTEIN PHOQ		response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;phosphorelay signal transduction system#GO:0000160;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transmembrane signal receptor#PC00197;histidine kinase receptor of two-component system#PC00265	
ECOLI|EnsemblGenome=b4272|UniProtKB=P0CF45	P0CF45	insC6	PTHR37936:SF3	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b2511|UniProtKB=P0A6P5	P0A6P5	der	PTHR43834:SF7	GTPASE DER	GTPASE DER-RELATED			cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	G-protein#PC00020	
ECOLI|EnsemblGenome=b0802|UniProtKB=P0AAX3	P0AAX3	ybiJ	PTHR34156:SF1	OUTER MEMBRANE PROTEIN-RELATED-RELATED	EXPORTED PROTEIN		response to stress#GO:0006950;response to stimulus#GO:0050896			
ECOLI|EnsemblGenome=b3816|UniProtKB=P0ABI4	P0ABI4	corA	PTHR47685:SF1	MAGNESIUM TRANSPORT PROTEIN CORA	MAGNESIUM TRANSPORT PROTEIN CORA	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transition metal ion transmembrane transporter activity#GO:0046915;magnesium ion transmembrane transporter activity#GO:0015095;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075				
ECOLI|EnsemblGenome=b2980|UniProtKB=P0ACL5	P0ACL5	glcC	PTHR43537:SF1	TRANSCRIPTIONAL REGULATOR, GNTR FAMILY	GLC OPERON TRANSCRIPTIONAL ACTIVATOR	sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700	regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355		helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b0076|UniProtKB=P10151	P10151	leuO	PTHR30118:SF6	HTH-TYPE TRANSCRIPTIONAL REGULATOR LEUO-RELATED	HTH-TYPE TRANSCRIPTIONAL REGULATOR LEUO	DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355	protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991	helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b2239|UniProtKB=P09394	P09394	glpQ	PTHR43620:SF50	GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE	GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE, PERIPLASMIC	phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824		extracellular region#GO:0005576;periplasmic space#GO:0042597;cellular anatomical structure#GO:0110165	hydrolase#PC00121;phosphodiesterase#PC00185	
ECOLI|EnsemblGenome=b0191|UniProtKB=P40711	P40711	arfB	PTHR47814:SF1	PEPTIDYL-TRNA HYDROLASE ARFB	PEPTIDYL-TRNA HYDROLASE ARFB	hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;carboxylic ester hydrolase activity#GO:0052689;binding#GO:0005488;protein-containing complex binding#GO:0044877;catalytic activity, acting on a tRNA#GO:0140101;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;hydrolase activity#GO:0016787	organelle organization#GO:0006996;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translational elongation#GO:0006414;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;rescue of stalled cytosolic ribosome#GO:0072344;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;translation#GO:0006412;organelle disassembly#GO:1903008;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411			
ECOLI|EnsemblGenome=b0910|UniProtKB=P0A6I0	P0A6I0	cmk	PTHR21299:SF2	CYTIDYLATE KINASE/PANTOATE-BETA-ALANINE LIGASE	CYTIDYLATE KINASE	catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879	monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;nucleobase-containing small molecule metabolic process#GO:0055086	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		Pantothenate biosynthesis#P02761>Pantoate-beta-alanine ligase#P03068
ECOLI|EnsemblGenome=b2081|UniProtKB=P76403	P76403	trhP	PTHR30217:SF13	PEPTIDASE U32 FAMILY	TRNA HYDROXYLATION PROTEIN P		macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	protease#PC00190	
ECOLI|EnsemblGenome=b0584|UniProtKB=P05825	P05825	fepA	PTHR30069:SF51	TONB-DEPENDENT OUTER MEMBRANE RECEPTOR	FERRIENTEROBACTIN RECEPTOR	xenobiotic transmembrane transporter activity#GO:0042910;siderophore-iron transmembrane transporter activity#GO:0015343;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;organic hydroxy compound transport#GO:0015850;iron coordination entity transport#GO:1901678;transition metal ion transport#GO:0000041;transport#GO:0006810;iron ion transport#GO:0006826;metal ion transport#GO:0030001	external encapsulating structure#GO:0030312;membrane#GO:0016020;cell outer membrane#GO:0009279;outer membrane#GO:0019867;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313		
ECOLI|EnsemblGenome=b3874|UniProtKB=P32135	P32135	yihN	PTHR43791:SF66	PERMEASE-RELATED	INNER MEMBRANE PROTEIN YIHN	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	primary active transporter#PC00068	
ECOLI|EnsemblGenome=b2339|UniProtKB=P77288	P77288	yfcV	PTHR33420:SF26	FIMBRIAL SUBUNIT ELFA-RELATED	MANNOSE-RESISTANT_PROTEUS-LIKE FIMBRIAL PROTEIN		cellular process#GO:0009987;cell adhesion#GO:0007155;single-species biofilm formation#GO:0044010;cell-substrate adhesion#GO:0031589	cellular anatomical structure#GO:0110165;cell projection#GO:0042995		
ECOLI|EnsemblGenome=b2960|UniProtKB=P0A8I5	P0A8I5	trmB	PTHR23417:SF14	3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA  GUANINE-N 7 - -METHYLTRANSFERASE	TRNA (GUANINE(46)-N(7))-METHYLTRANSFERASE	S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173	macromolecule modification#GO:0043412;methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;cellular process#GO:0009987	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494	RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b1782|UniProtKB=P0A908	P0A908	mipA	PTHR38776:SF1	MLTA-INTERACTING PROTEIN-RELATED	MLTA-INTERACTING PROTEIN-RELATED		aminoglycan metabolic process#GO:0006022;cell wall biogenesis#GO:0042546;cell wall macromolecule metabolic process#GO:0044036;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan metabolic process#GO:0030203;peptidoglycan biosynthetic process#GO:0009252;peptidoglycan-based cell wall biogenesis#GO:0009273;peptidoglycan metabolic process#GO:0000270;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;glycosaminoglycan biosynthetic process#GO:0006024;cell wall macromolecule biosynthetic process#GO:0044038;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;cell wall organization or biogenesis#GO:0071554;biosynthetic process#GO:0009058	outer membrane#GO:0019867;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;membrane#GO:0016020;cell outer membrane#GO:0009279;cell envelope#GO:0030313;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0611|UniProtKB=P21338	P21338	rna	PTHR11240:SF88	RIBONUCLEASE T2	RIBONUCLEASE I		cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070		endoribonuclease#PC00094	
ECOLI|EnsemblGenome=b1829|UniProtKB=P23894	P23894	htpX	PTHR43221:SF1	PROTEASE HTPX	PROTEASE HTPX	catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222	protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	protease#PC00190;protein modifying enzyme#PC00260;metalloprotease#PC00153	
ECOLI|EnsemblGenome=b1013|UniProtKB=P0ACU2	P0ACU2	rutR	PTHR30055:SF196	HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR	HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR	nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090		Tet repressor-like transcription factor#PC00266	
ECOLI|EnsemblGenome=b0137|UniProtKB=P37017	P37017	yadL	PTHR33420:SF12	FIMBRIAL SUBUNIT ELFA-RELATED	FIMBRIN-LIKE PROTEIN FIMI-RELATED		cell-substrate adhesion#GO:0031589;cell adhesion#GO:0007155;cellular process#GO:0009987;single-species biofilm formation#GO:0044010	cellular anatomical structure#GO:0110165;cell projection#GO:0042995		
ECOLI|EnsemblGenome=b3117|UniProtKB=P0AGF6	P0AGF6	tdcB	PTHR48078:SF6	THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED	L-THREONINE DEHYDRATASE CATABOLIC TDCB	lyase activity#GO:0016829;catalytic activity#GO:0003824	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752		lyase#PC00144;dehydratase#PC00091	Isoleucine biosynthesis#P02748>Threonine dehydratase#P02995
ECOLI|EnsemblGenome=b3380|UniProtKB=P45549	P45549	yhfW	PTHR21110:SF0	PHOSPHOPENTOMUTASE	PHOSPHOPENTOMUTASE	isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;intramolecular phosphotransferase activity#GO:0016868	metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	isomerase#PC00135;mutase#PC00160	PRPP biosynthesis#P02760>Phosphopentose mutase#P03064
ECOLI|EnsemblGenome=b3417|UniProtKB=P00490	P00490	malP	PTHR11468:SF25	GLYCOGEN PHOSPHORYLASE	MALTODEXTRIN PHOSPHORYLASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757	glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042;polysaccharide catabolic process#GO:0000272;catabolic process#GO:0009056;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;glucan catabolic process#GO:0009251;energy reserve metabolic process#GO:0006112;carbohydrate catabolic process#GO:0016052;glycogen catabolic process#GO:0005980;cellular process#GO:0009987;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;generation of precursor metabolites and energy#GO:0006091;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	glycosyltransferase#PC00111;transferase#PC00220	
ECOLI|EnsemblGenome=b3974|UniProtKB=P0A6I3	P0A6I3	coaA	PTHR10285:SF139	URIDINE KINASE	PANTOTHENATE KINASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773	primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	nucleotide kinase#PC00172;kinase#PC00137	
ECOLI|EnsemblGenome=b2194|UniProtKB=P0ABM9	P0ABM9	ccmH	PTHR47870:SF1	CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCMH	CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCMH					
ECOLI|EnsemblGenome=b3478|UniProtKB=P0AFA9	P0AFA9	nikC	PTHR43386:SF28	OLIGOPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN APPC	D,D-DIPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN DDPC-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;oligopeptide transmembrane transporter activity#GO:0035673;dipeptide transmembrane transporter activity#GO:0071916		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b3415|UniProtKB=P39835	P39835	gntT	PTHR30354:SF22	GNT FAMILY GLUCONATE TRANSPORTER	HIGH-AFFINITY GLUCONATE TRANSPORTER	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;carbohydrate transmembrane transporter activity#GO:0015144;monocarboxylic acid transmembrane transporter activity#GO:0008028	localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monocarboxylic acid transport#GO:0015718;carbohydrate transport#GO:0008643;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;carbohydrate transmembrane transport#GO:0034219;carboxylic acid transmembrane transport#GO:1905039;cellular process#GO:0009987	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227;secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b2452|UniProtKB=P76552	P76552	eutH	PTHR40089:SF1	ETHANOLAMINE UTILIZATION PROTEIN EUTH	ETHANOLAMINE PERMEASE EUTH-RELATED			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b2669|UniProtKB=P0ACG1	P0ACG1	stpA	PTHR38097:SF2	FAMILY NOT NAMED	DNA-BINDING PROTEIN STPA					
ECOLI|EnsemblGenome=b2877|UniProtKB=Q46810	Q46810	mocA	PTHR43777:SF1	MOLYBDENUM COFACTOR CYTIDYLYLTRANSFERASE	MOLYBDENUM COFACTOR CYTIDYLYLTRANSFERASE	transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779	nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;nucleotide metabolic process#GO:0009117;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;macromolecule metabolic process#GO:0043170;nucleoside phosphate biosynthetic process#GO:1901293;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058		transferase#PC00220	
ECOLI|EnsemblGenome=b0978|UniProtKB=P26459	P26459	appC	PTHR30365:SF7	CYTOCHROME D UBIQUINOL OXIDASE	CYTOCHROME BD-II UBIQUINOL OXIDASE SUBUNIT 1	tetrapyrrole binding#GO:0046906;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;oxidoreductase activity, acting on diphenols and related substances as donors#GO:0016679;binding#GO:0005488;catalytic activity#GO:0003824	cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;catalytic complex#GO:1902494;cytochrome complex#GO:0070069	metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3960|UniProtKB=P11447	P11447	argH	PTHR43814:SF1	ARGININOSUCCINATE LYASE	ARGININOSUCCINATE LYASE	lyase activity#GO:0016829;catalytic activity#GO:0003824	primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;biosynthetic process#GO:0009058;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;L-arginine biosynthetic process#GO:0006526	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	lyase#PC00144	Arginine biosynthesis#P02728>argininosuccinate lyase#P02841
ECOLI|EnsemblGenome=b2801|UniProtKB=P11551	P11551	fucP	PTHR43702:SF3	L-FUCOSE-PROTON SYMPORTER	L-FUCOSE-PROTON SYMPORTER	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857			transporter#PC00227;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b3743|UniProtKB=P0ACI6	P0ACI6	asnC	PTHR43413:SF6	TRANSCRIPTIONAL REGULATOR, ASNC FAMILY	REGULATORY PROTEIN ASNC	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252		helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b2632|UniProtKB=P52131	P52131	yfjP	PTHR42714:SF2	TRNA MODIFICATION GTPASE GTPBP3	TRNA MODIFICATION GTPASE MNME		RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA methylation#GO:0001510;methylation#GO:0032259;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	RNA methyltransferase#PC00033;RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b4030|UniProtKB=P0A7C8	P0A7C8	psiE	PTHR37819:SF1	PROTEIN PSIE	PROTEIN PSIE			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b2331|UniProtKB=P0A8B2	P0A8B2	smrB	PTHR35562:SF1	DNA ENDONUCLEASE SMRA-RELATED	RIBOSOME RESCUE FACTOR SMRB	nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824	organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;translation#GO:0006412;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;rescue of stalled cytosolic ribosome#GO:0072344;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;translational elongation#GO:0006414;gene expression#GO:0010467;biosynthetic process#GO:0009058;organelle organization#GO:0006996;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059		DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b3517|UniProtKB=P69908	P69908	gadA	PTHR43321:SF3	GLUTAMATE DECARBOXYLASE	GLUTAMATE DECARBOXYLASE	catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829	amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;decarboxylase#PC00089	
ECOLI|EnsemblGenome=b3830|UniProtKB=P56262	P56262	ysgA	PTHR46623:SF6	CARBOXYMETHYLENEBUTENOLIDASE-RELATED	ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN					
ECOLI|EnsemblGenome=b3486|UniProtKB=P37624	P37624	rbbA	PTHR43038:SF4	ATP-BINDING CASSETTE, SUB-FAMILY H, MEMBER 1	RIBOSOME-ASSOCIATED ATPASE			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227	
ECOLI|EnsemblGenome=b4075|UniProtKB=P32711	P32711	nrfF	PTHR47870:SF2	CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCMH	FORMATE-DEPENDENT NITRITE REDUCTASE COMPLEX SUBUNIT NRFF			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b0413|UniProtKB=P0A8D0	P0A8D0	nrdR	PTHR30455:SF2	TRANSCRIPTIONAL REPRESSOR NRDR	TRANSCRIPTIONAL REPRESSOR NRDR	double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676	negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252		DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b3196|UniProtKB=P45394	P45394	yrbG	PTHR10846:SF8	SODIUM/POTASSIUM/CALCIUM EXCHANGER	INNER MEMBRANE PROTEIN YRBG	monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;antiporter activity#GO:0015297;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803	monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;metal ion transport#GO:0030001;homeostatic process#GO:0042592;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b3110|UniProtKB=P42628	P42628	dlsT	PTHR35334:SF4	SERINE TRANSPORTER	SERINE TRANSPORTER-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	transport#GO:0006810;amino acid transport#GO:0006865;establishment of localization#GO:0051234;localization#GO:0051179	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b3533|UniProtKB=P37653	P37653	bcsA	PTHR43867:SF2	CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]	CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]	hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757	primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042;beta-glucan metabolic process#GO:0051273;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;beta-glucan biosynthetic process#GO:0051274;polysaccharide metabolic process#GO:0005976;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;cellulose biosynthetic process#GO:0030244;polysaccharide biosynthetic process#GO:0000271;glucan biosynthetic process#GO:0009250;macromolecule metabolic process#GO:0043170	cellular anatomical structure#GO:0110165;membrane#GO:0016020		
ECOLI|EnsemblGenome=b1538|UniProtKB=P24171	P24171	dcp	PTHR43660:SF1	DIPEPTIDYL CARBOXYPEPTIDASE	DIPEPTIDYL CARBOXYPEPTIDASE	catalytic activity#GO:0003824;peptidase activity#GO:0008233;carboxypeptidase activity#GO:0004180;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787	metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	metalloprotease#PC00153;protease#PC00190	
ECOLI|EnsemblGenome=b3461|UniProtKB=P0AGB3	P0AGB3	rpoH	PTHR30376:SF3	SIGMA FACTOR RPOH  HEAT SHOCK  RELATED	RNA POLYMERASE SIGMA FACTOR RPOH				helix-turn-helix transcription factor#PC00116;Sigma factor#PC00267;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b0085|UniProtKB=P22188	P22188	murE	PTHR23135:SF4	MUR LIGASE FAMILY MEMBER	UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--2,6-DIAMINOPIMELATE LIGASE	catalytic activity#GO:0003824;ligase activity#GO:0016874			ligase#PC00142	Peptidoglycan biosynthesis#P02763>UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase#P03084
ECOLI|EnsemblGenome=b3835|UniProtKB=P0A6A0	P0A6A0	ubiB	PTHR10566:SF129	CHAPERONE-ACTIVITY OF BC1 COMPLEX  CABC1 -RELATED	PROTEIN KINASE UBIB-RELATED					
ECOLI|EnsemblGenome=b2063|UniProtKB=P76389	P76389	yegH	PTHR22777:SF30	HEMOLYSIN-RELATED	UPF0053 PROTEIN YEGH			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b1132|UniProtKB=P25746	P25746	hflD	PTHR38100:SF1	HIGH FREQUENCY LYSOGENIZATION PROTEIN HFLD	HIGH FREQUENCY LYSOGENIZATION PROTEIN HFLD					
ECOLI|EnsemblGenome=b4385|UniProtKB=P39410	P39410	yjjJ	PTHR37419:SF8	SERINE/THREONINE-PROTEIN KINASE TOXIN HIPA	TOXIN YJJJ	catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	non-receptor serine/threonine protein kinase#PC00167	
ECOLI|EnsemblGenome=b3850|UniProtKB=P0ACB4	P0ACB4	hemG	PTHR38030:SF2	PROTOPORPHYRINOGEN IX DEHYDROGENASE [MENAQUINONE]	PROTOPORPHYRINOGEN IX DEHYDROGENASE [QUINONE]	ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;carbohydrate derivative binding#GO:0097367;catalytic activity#GO:0003824;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166	pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;cellular process#GO:0009987;tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148;porphyrin-containing compound biosynthetic process#GO:0006779		metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b3181|UniProtKB=P0A6W5	P0A6W5	greA	PTHR30437:SF4	TRANSCRIPTION ELONGATION FACTOR GREA	TRANSCRIPTION ELONGATION FACTOR GREA		macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription elongation#GO:0006354;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;DNA-templated transcription#GO:0006351;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070			
ECOLI|EnsemblGenome=b0215|UniProtKB=P03007	P03007	dnaQ	PTHR30231:SF41	DNA POLYMERASE III SUBUNIT EPSILON	DNA POLYMERASE III SUBUNIT EPSILON	catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;3'-5' exonuclease activity#GO:0008408;nuclease activity#GO:0004518	nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b1743|UniProtKB=P77754	P77754	spy	PTHR38102:SF1	PERIPLASMIC CHAPERONE SPY	PERIPLASMIC CHAPERONE SPY				chaperone#PC00072	
ECOLI|EnsemblGenome=b1592|UniProtKB=P76175	P76175	clcB	PTHR43427:SF6	CHLORIDE CHANNEL PROTEIN CLC-E	VOLTAGE-GATED CLC-TYPE CHLORIDE CHANNEL CLCB		establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;transport#GO:0006810;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987		ion channel#PC00133	
ECOLI|EnsemblGenome=b0416|UniProtKB=P0A780	P0A780	nusB	PTHR11078:SF5	N UTILIZATION SUBSTANCE PROTEIN B-RELATED	TRANSCRIPTION ANTITERMINATION PROTEIN NUSB			cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		
ECOLI|EnsemblGenome=b1644|UniProtKB=P76185	P76185	ydhJ	PTHR30367:SF13	P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT AAEA-RELATED	MULTIDRUG RESISTANCE EFFLUX PUMP	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179			
ECOLI|EnsemblGenome=b0677|UniProtKB=P0AF18	P0AF18	nagA	PTHR11113:SF14	N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE	N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE	deacetylase activity#GO:0019213;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;deacylase activity#GO:0160215;catalytic activity#GO:0003824	carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;metabolic process#GO:0008152;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;amino sugar catabolic process#GO:0046348		metabolite interconversion enzyme#PC00262;deacetylase#PC00087	N-acetylglucosamine metabolism#P02756>N-acetylglucosamine-6-phosphate deacetylase#P03036
ECOLI|EnsemblGenome=b2027|UniProtKB=P76372	P76372	wzzB	PTHR32309:SF29	TYROSINE-PROTEIN KINASE	CHAIN LENGTH DETERMINANT PROTEIN	transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	non-receptor tyrosine protein kinase#PC00168	
ECOLI|EnsemblGenome=b4352|UniProtKB=P24203	P24203	yjiA	PTHR13748:SF31	COBW-RELATED	ZINC-REGULATED GTPASE METALLOPROTEIN ACTIVATOR 1A-RELATED	transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;molecular carrier activity#GO:0140104;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;zinc ion binding#GO:0008270	macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		
ECOLI|Gene_OrderedLocusName=JW0291|UniProtKB=P36943	P36943	eaeH	PTHR39576:SF2	ATTACHING AND EFFACING PROTEIN HOMOLOG-RELATED-RELATED	INVERSE AUTOTRANSPORTER ADHESIN YEEJ-RELATED			cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;cell outer membrane#GO:0009279;membrane#GO:0016020;external encapsulating structure#GO:0030312;outer membrane#GO:0019867;extracellular region#GO:0005576		
ECOLI|EnsemblGenome=b2184|UniProtKB=P33919	P33919	radD	PTHR47962:SF7	ATP-DEPENDENT HELICASE LHR-RELATED-RELATED	MITOCHONDRIAL ATP-DEPENDENT HELICASE IRC3-RELATED	hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP hydrolysis activity#GO:0016887;DNA binding#GO:0003677;hydrolase activity#GO:0016787				
ECOLI|EnsemblGenome=b2055|UniProtKB=P71239	P71239	wcaE	PTHR22916:SF67	GLYCOSYLTRANSFERASE	COLANIC ACID BIOSYNTHESIS GLYCOSYL TRANSFERASE WCAE-RELATED	hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757			transferase#PC00220;glycosyltransferase#PC00111	
ECOLI|EnsemblGenome=b4107|UniProtKB=P16681	P16681	yjdN	PTHR33990:SF1	PROTEIN YJDN-RELATED	PROTEIN YJDN					
ECOLI|EnsemblGenome=b2132|UniProtKB=P33363	P33363	bglX	PTHR30620:SF125	PERIPLASMIC BETA-GLUCOSIDASE-RELATED	PERIPLASMIC BETA-GLUCOSIDASE	hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;glucosidase activity#GO:0015926;beta-glucosidase activity#GO:0008422;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553	glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;polysaccharide catabolic process#GO:0000272;cellular process#GO:0009987;catabolic process#GO:0009056;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;glucan catabolic process#GO:0009251;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;carbohydrate catabolic process#GO:0016052;macromolecule metabolic process#GO:0043170	extracellular region#GO:0005576;periplasmic space#GO:0042597;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313	metabolite interconversion enzyme#PC00262;glucosidase#PC00108	
ECOLI|EnsemblGenome=b0200|UniProtKB=P63228	P63228	gmhB	PTHR42891:SF1	D-GLYCERO-BETA-D-MANNO-HEPTOSE-1,7-BISPHOSPHATE 7-PHOSPHATASE	D-GLYCERO-BETA-D-MANNO-HEPTOSE-1,7-BISPHOSPHATE 7-PHOSPHATASE				phosphatase#PC00181;hydrolase#PC00121	
ECOLI|EnsemblGenome=b4289|UniProtKB=P15030	P15030	fecC	PTHR30472:SF1	FERRIC ENTEROBACTIN TRANSPORT SYSTEM PERMEASE PROTEIN	FE(3+) DICITRATE TRANSPORT SYSTEM PERMEASE PROTEIN FECC-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	iron coordination entity transport#GO:1901678;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;siderophore-iron import into cell#GO:0033214;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;iron ion transport#GO:0006826;siderophore-dependent iron import pathway#GO:0180060;cellular localization#GO:0051641;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;iron import into cell#GO:0033212;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;metal ion transport#GO:0030001	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b3712|UniProtKB=P0ADM8	P0ADM8	yieE	PTHR12215:SF22	PHOSPHOPANTETHEINE TRANSFERASE	CYTOPLASMIC PROTEIN	catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772	protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	transferase#PC00220;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0658|UniProtKB=P0AE78	P0AE78	corC	PTHR22777:SF27	HEMOLYSIN-RELATED	MAGNESIUM AND COBALT EFFLUX PROTEIN CORC			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b3592|UniProtKB=P0ACA1	P0ACA1	yibF	PTHR42673:SF23	MALEYLACETOACETATE ISOMERASE	BLR7892 PROTEIN	isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;catalytic activity#GO:0003824	primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749		isomerase#PC00135	
ECOLI|EnsemblGenome=b3422|UniProtKB=P38035	P38035	rtcR	PTHR32071:SF14	TRANSCRIPTIONAL REGULATORY PROTEIN	TRANSCRIPTIONAL REGULATORY PROTEIN RTCR	sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987	regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557	protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991	DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b0298|UniProtKB=P0CF66	P0CF66	insE1	PTHR33215:SF6	PROTEIN DISTAL ANTENNA	TRANSPOSASE INSE FOR INSERTION SEQUENCE IS3A-RELATED					
ECOLI|EnsemblGenome=b4232|UniProtKB=P0A993	P0A993	fbp	PTHR11556:SF44	FRUCTOSE-1,6-BISPHOSPHATASE-RELATED	FRUCTOSE-1,6-BISPHOSPHATASE CLASS 1	catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;sugar-phosphatase activity#GO:0050308;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787	small molecule metabolic process#GO:0044281;carbohydrate biosynthetic process#GO:0016051;carbohydrate metabolic process#GO:0005975;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular process#GO:0009987;gluconeogenesis#GO:0006094;hexose biosynthetic process#GO:0019319;glucose metabolic process#GO:0006006;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	phosphatase#PC00181;carbohydrate phosphatase#PC00066;hydrolase#PC00121	
ECOLI|EnsemblGenome=b0564|UniProtKB=P05052	P05052	appY	PTHR43280:SF33	ARAC-FAMILY TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR APPY-RELATED	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222		helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b2948|UniProtKB=P0A8W5	P0A8W5	yqgE	PTHR30327:SF1	UNCHARACTERIZED PROTEIN YQGE	UPF0301 PROTEIN YQGE			cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b3859|UniProtKB=P0C0K3	P0C0K3	srkA	PTHR39573:SF1	STRESS RESPONSE KINASE A	STRESS RESPONSE KINASE A	protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096	response to stimulus#GO:0050896;response to stress#GO:0006950	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		
ECOLI|EnsemblGenome=b0064|UniProtKB=P0A9E0	P0A9E0	araC	PTHR43280:SF25	ARAC-FAMILY TRANSCRIPTIONAL REGULATOR	ARABINOSE OPERON REGULATORY PROTEIN	transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889		helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b2382|UniProtKB=P77396	P77396	ypdC	PTHR43280:SF10	ARAC-FAMILY TRANSCRIPTIONAL REGULATOR	TRANSCRIPTIONAL REGULATOR	transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219		DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b0420|UniProtKB=P77488	P77488	dxs	PTHR43322:SF5	1-D-DEOXYXYLULOSE 5-PHOSPHATE SYNTHASE-RELATED	1-DEOXY-D-XYLULOSE-5-PHOSPHATE SYNTHASE, CHLOROPLASTIC	transferase activity#GO:0016740;catalytic activity#GO:0003824;transketolase or transaldolase activity#GO:0016744			transferase#PC00220	Thiamin biosynthesis#P02779>1-Deoxyxylulose-5-phosphate synthase#P03175;Vitamin B6 biosynthesis#P02786>1-Deoxyxylulose-5-phosphate synthase#P03225;Pyridoxal-5-phosphate biosynthesis#P02759>1-Deoxyxylulose-5-phosphate synthase#P03062
ECOLI|EnsemblGenome=b2919|UniProtKB=P52045	P52045	scpB	PTHR11941:SF54	ENOYL-COA HYDRATASE-RELATED	2,3-DEHYDROADIPYL-COA HYDRATASE-RELATED		fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;lipid modification#GO:0030258;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042		lyase#PC00144;hydratase#PC00120;metabolite interconversion enzyme#PC00262	Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163
ECOLI|EnsemblGenome=b3513|UniProtKB=P37636	P37636	mdtE	PTHR30158:SF3	ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER	MULTIDRUG EFFLUX PUMP SUBUNIT ACRA-RELATED		transport#GO:0006810;xenobiotic transport#GO:0042908;response to antibiotic#GO:0046677;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;detoxification#GO:0098754;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to toxic substance#GO:0009636	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b0760|UniProtKB=P31060	P31060	modF	PTHR43553:SF3	HEAVY METAL TRANSPORTER	ABC TRANSPORTER ATP-BINDING PROTEIN MODF	heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;ATP binding#GO:0005524;nucleotide binding#GO:0000166;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transmembrane transporter activity#GO:0022857;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094		membrane protein complex#GO:0098796;membrane#GO:0016020;ATP-binding cassette (ABC) transporter complex#GO:0043190;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;ATPase dependent transmembrane transport complex#GO:0098533	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227	
ECOLI|EnsemblGenome=b4221|UniProtKB=P39321	P39321	tamB	PTHR36985:SF1	TRANSLOCATION AND ASSEMBLY MODULE SUBUNIT TAMB	TRANSLOCATION AND ASSEMBLY MODULE SUBUNIT TAMB		transport#GO:0006810;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular process#GO:0009987;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;localization within membrane#GO:0051668;protein transport#GO:0015031;secretion by cell#GO:0032940;secretion#GO:0046903;cellular localization#GO:0051641;protein secretion#GO:0009306;localization#GO:0051179;protein localization to extracellular region#GO:0071692;protein localization to membrane#GO:0072657;export from cell#GO:0140352	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0410|UniProtKB=P0AAQ2	P0AAQ2	yajD	PTHR41286:SF1	HNH NUCLEASE YAJD-RELATED	HNH NUCLEASE YAJD-RELATED			cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b1095|UniProtKB=P0AAI5	P0AAI5	fabF	PTHR11712:SF336	POLYKETIDE SYNTHASE-RELATED	3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 2	acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746	carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330			
ECOLI|EnsemblGenome=b2475|UniProtKB=P64429	P64429	ypfJ	PTHR30168:SF0	PUTATIVE MEMBRANE PROTEIN YPFJ	NEUTRAL ZINC METALLOPEPTIDASE FAMILY PROTEIN					
ECOLI|EnsemblGenome=b0975|UniProtKB=P19930	P19930	hyaD	PTHR30302:SF9	HYDROGENASE 1 MATURATION PROTEASE	HYDROGENASE 1 MATURATION PROTEASE	catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096	primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538		aspartic protease#PC00053;protease#PC00190	
ECOLI|EnsemblGenome=b2265|UniProtKB=P38051	P38051	menF	PTHR47253:SF9	FAMILY NOT NAMED	ISOCHORISMATE SYNTHASE MENF	isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866	metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;ketone metabolic process#GO:0042180;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;menaquinone biosynthetic process#GO:0009234			
ECOLI|EnsemblGenome=b1736|UniProtKB=P69791	P69791	chbA	PTHR34382:SF11	PTS SYSTEM N,N'-DIACETYLCHITOBIOSE-SPECIFIC EIIA COMPONENT	PTS SYSTEM N,N'-DIACETYLCHITOBIOSE-SPECIFIC EIIA COMPONENT	transferase activity#GO:0016740;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transferase activity, transferring phosphorus-containing groups#GO:0016772;active transmembrane transporter activity#GO:0022804;protein-phosphocysteine-sugar phosphotransferase activity#GO:0090563;phosphotransferase activity, alcohol group as acceptor#GO:0016773;carbohydrate transmembrane transporter activity#GO:0015144	phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;localization#GO:0051179;import into cell#GO:0098657;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;carbohydrate transport#GO:0008643;transport#GO:0006810;import across plasma membrane#GO:0098739;carbohydrate transmembrane transport#GO:0034219;cellular process#GO:0009987			
ECOLI|EnsemblGenome=b1380|UniProtKB=P52643	P52643	ldhA	PTHR43026:SF1	2-HYDROXYACID DEHYDROGENASE HOMOLOG 1-RELATED	D-LACTATE DEHYDROGENASE	catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614			metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b0284|UniProtKB=P77489	P77489	paoC	PTHR11908:SF123	XANTHINE DEHYDROGENASE	ALDEHYDE OXIDOREDUCTASE MOLYBDENUM-BINDING SUBUNIT PAOC	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2283|UniProtKB=P33602	P33602	nuoG	PTHR43105:SF10	RESPIRATORY NITRATE REDUCTASE	NADH-QUINONE OXIDOREDUCTASE SUBUNIT G			membrane#GO:0016020;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176;reductase#PC00198	
ECOLI|EnsemblGenome=b1187|UniProtKB=P0A8V6	P0A8V6	fadR	PTHR43537:SF52	TRANSCRIPTIONAL REGULATOR, GNTR FAMILY	FATTY ACID METABOLISM REGULATOR PROTEIN	DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789		winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b0597|UniProtKB=P0A8Y8	P0A8Y8	entH	PTHR43240:SF9	1,4-DIHYDROXY-2-NAPHTHOYL-COA THIOESTERASE 1	PROOFREADING THIOESTERASE ENTH	hydrolase activity#GO:0016787;catalytic activity#GO:0003824;acyl-CoA hydrolase activity#GO:0016289;deacylase activity#GO:0160215;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	metabolite interconversion enzyme#PC00262;esterase#PC00097	
ECOLI|EnsemblGenome=b3686|UniProtKB=P0C058	P0C058	ibpB	PTHR47062:SF2	SMALL HEAT SHOCK PROTEIN IBPA	SMALL HEAT SHOCK PROTEIN IBPB			cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		
ECOLI|EnsemblGenome=b3250|UniProtKB=P16926	P16926	mreC	PTHR34138:SF1	CELL SHAPE-DETERMINING PROTEIN MREC	CELL SHAPE-DETERMINING PROTEIN MREC		regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;biological regulation#GO:0065007;regulation of developmental process#GO:0050793;regulation of biological quality#GO:0065008;regulation of anatomical structure morphogenesis#GO:0022603	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b4350|UniProtKB=P08956	P08956	hsdR	PTHR47396:SF1	TYPE I RESTRICTION ENZYME ECOKI R PROTEIN	TYPE I RESTRICTION ENZYME ECOKI ENDONUCLEASE SUBUNIT		cellular process#GO:0009987;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;nucleobase-containing compound metabolic process#GO:0006139;defense response to other organism#GO:0098542;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;defense response#GO:0006952;response to external stimulus#GO:0009605;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;macromolecule modification#GO:0043412	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b1735|UniProtKB=P17410	P17410	chbR	PTHR43280:SF12	ARAC-FAMILY TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR CHBR	transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889		DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b1477|UniProtKB=P67699	P67699	yddM	PTHR36924:SF1	ANTITOXIN HIGA-1	ANTITOXIN HIGA-1		regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468			
ECOLI|EnsemblGenome=b4154|UniProtKB=P00363	P00363	frdA	PTHR11632:SF82	SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT	FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT		cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;anaerobic respiration#GO:0009061;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980	catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;respiratory chain complex#GO:0098803;cell periphery#GO:0071944	dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b0080|UniProtKB=P0ACP1	P0ACP1	cra	PTHR30146:SF45	LACI-RELATED TRANSCRIPTIONAL REPRESSOR	CATABOLITE REPRESSOR_ACTIVATOR	double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007		Lambda repressor-like transcription factor#PC00245;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b0852|UniProtKB=P0C0U4	P0C0U4	rimK	PTHR21621:SF7	RIBOSOMAL PROTEIN S6 MODIFICATION PROTEIN	RIBOSOMAL PROTEIN BS6--L-GLUTAMATE LIGASE	ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on a protein#GO:0140096	response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;SOS response#GO:0009432;cellular response to stress#GO:0033554;DNA damage response#GO:0006974	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	ribosomal protein#PC00202;translational protein#PC00263	
ECOLI|EnsemblGenome=b0681|UniProtKB=P75733	P75733	chiP	PTHR34596:SF3	CHITOPORIN	CHITOPORIN	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829	localization#GO:0051179;establishment of localization#GO:0051234;carbohydrate transport#GO:0008643;transport#GO:0006810			
ECOLI|EnsemblGenome=b0820|UniProtKB=P0A9U3	P0A9U3	ybiT	PTHR19211:SF96	ATP-BINDING TRANSPORT PROTEIN-RELATED	ATP-BINDING PROTEIN YBIT-RELATED	ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ATP binding#GO:0005524			translation elongation factor#PC00222	
ECOLI|EnsemblGenome=b1887|UniProtKB=P0A964	P0A964	cheW	PTHR22617:SF45	CHEMOTAXIS SENSOR HISTIDINE KINASE-RELATED	CHEMOTAXIS PROTEIN CHEW		response to external stimulus#GO:0009605;cell communication#GO:0007154;chemotaxis#GO:0006935;signaling#GO:0023052;biological regulation#GO:0065007;locomotion#GO:0040011;taxis#GO:0042330;response to chemical#GO:0042221;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987	protein-containing complex#GO:0032991	histidine kinase receptor of two-component system#PC00265	
ECOLI|EnsemblGenome=b2860|UniProtKB=P0CF56	P0CF56	insD4	PTHR37936:SF3	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b3428|UniProtKB=P0AC86	P0AC86	glgP	PTHR11468:SF3	GLYCOGEN PHOSPHORYLASE	GLYCOGEN PHOSPHORYLASE, LIVER FORM	transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757	carbohydrate catabolic process#GO:0016052;energy reserve metabolic process#GO:0006112;glucan catabolic process#GO:0009251;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;catabolic process#GO:0009056;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;generation of precursor metabolites and energy#GO:0006091;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular process#GO:0009987;glycogen catabolic process#GO:0005980	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	transferase#PC00220;glycosyltransferase#PC00111	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase a#P00718;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b#P00717
ECOLI|EnsemblGenome=b1213|UniProtKB=Q46755	Q46755	ychQ	PTHR39594:SF1	PROTEIN YCHQ	PROTEIN YCHQ			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b3431|UniProtKB=P15067	P15067	glgX	PTHR43002:SF3	GLYCOGEN DEBRANCHING ENZYME	GLYCOGEN DEBRANCHING ENZYME				amylase#PC00048;hydrolase#PC00121	
ECOLI|EnsemblGenome=b4173|UniProtKB=P25519	P25519	hflX	PTHR10229:SF0	GTP-BINDING PROTEIN HFLX	GTP-BINDING PROTEIN 6-RELATED	binding#GO:0005488;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021		intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0157|UniProtKB=P0AFP0	P0AFP0	yadS	PTHR30506:SF3	INNER MEMBRANE PROTEIN	UPF0126 INNER MEMBRANE PROTEIN YADS-RELATED			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b0484|UniProtKB=Q59385	Q59385	copA	PTHR43520:SF6	ATP7, ISOFORM B	COPPER-EXPORTING P-TYPE ATPASE	transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914;cation binding#GO:0043169;copper ion binding#GO:0005507;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;metal ion transmembrane transporter activity#GO:0046873;binding#GO:0005488;transition metal ion transmembrane transporter activity#GO:0046915;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;metal ion binding#GO:0046872;monoatomic cation transmembrane transporter activity#GO:0008324	homeostatic process#GO:0042592;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801	membrane#GO:0016020;cellular anatomical structure#GO:0110165	primary active transporter#PC00068	
ECOLI|EnsemblGenome=b0435|UniProtKB=P0ABE2	P0ABE2	bolA	PTHR46229:SF5	BOLA TRANSCRIPTION REGULATOR	DNA-BINDING TRANSCRIPTIONAL REGULATOR BOLA					
ECOLI|EnsemblGenome=b2763|UniProtKB=P17846	P17846	cysI	PTHR11493:SF65	SULFITE REDUCTASE [NADPH] SUBUNIT BETA-RELATED	SULFITE REDUCTASE [NADPH] HEMOPROTEIN BETA-COMPONENT		cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790	catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991	reductase#PC00198	
ECOLI|EnsemblGenome=b1313|UniProtKB=P76043	P76043	ycjQ	PTHR43350:SF19	NAD-DEPENDENT ALCOHOL DEHYDROGENASE	D-GULOSIDE 3-DEHYDROGENASE	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b3939|UniProtKB=P00935	P00935	metB	PTHR11808:SF75	TRANS-SULFURATION ENZYME FAMILY MEMBER	CYSTATHIONINE GAMMA-SYNTHASE	lyase activity#GO:0016829;carbon-sulfur lyase activity#GO:0016846;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;heterocyclic compound binding#GO:1901363;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824	amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;homocysteine metabolic process#GO:0050667;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;carboxylic acid metabolic process#GO:0019752;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	lyase#PC00144;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0234|UniProtKB=Q47158	Q47158	yafP	PTHR43451:SF1	ACETYLTRANSFERASE (GNAT) FAMILY PROTEIN	INDOLAMINE N-ACETYLTRANSFERASE 4				acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262	
ECOLI|Gene_OrderedLocusName=JW0551|UniProtKB=P77460	P77460	ybcY	PTHR43591:SF24	METHYLTRANSFERASE	METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN	catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168			methyltransferase#PC00155;transferase#PC00220	
ECOLI|EnsemblGenome=b0402|UniProtKB=P0AAE2	P0AAE2	proY	PTHR43341:SF8	AMINO ACID PERMEASE	PROLINE-SPECIFIC PERMEASE PROY	amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	localization#GO:0051179;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;cellular process#GO:0009987;amino acid transport#GO:0006865;transport#GO:0006810	cellular anatomical structure#GO:0110165;membrane#GO:0016020	amino acid transporter#PC00046;transporter#PC00227	
ECOLI|EnsemblGenome=b3785|UniProtKB=P0AG00	P0AG00	wzzE	PTHR32309:SF16	TYROSINE-PROTEIN KINASE	ECA POLYSACCHARIDE CHAIN LENGTH MODULATION PROTEIN	phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	non-receptor tyrosine protein kinase#PC00168	
ECOLI|EnsemblGenome=b1242|UniProtKB=P25743	P25743	ychE	PTHR33508:SF1	UPF0056 MEMBRANE PROTEIN YHCE	UPF0056 MEMBRANE PROTEIN YHCE					
ECOLI|EnsemblGenome=b2175|UniProtKB=P0AFV4	P0AFV4	mepS	PTHR47360:SF3	MUREIN DD-ENDOPEPTIDASE MEPS/MUREIN LD-CARBOXYPEPTIDASE	MUREIN DD-ENDOPEPTIDASE MEPS_MUREIN LD-CARBOXYPEPTIDASE	catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233	peptidoglycan turnover#GO:0009254;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;peptidoglycan metabolic process#GO:0000270			
ECOLI|EnsemblGenome=b4078|UniProtKB=P0AF56	P0AF56	yjcO	PTHR43628:SF1	ACTIVATOR OF C KINASE PROTEIN 1-RELATED	B BOX-TYPE DOMAIN-CONTAINING PROTEIN-RELATED					
ECOLI|EnsemblGenome=b2953|UniProtKB=P52060	P52060	yggU	PTHR13420:SF7	UPF0235 PROTEIN C15ORF40	UPF0235 PROTEIN C15ORF40			cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b3347|UniProtKB=P45523	P45523	fkpA	PTHR43811:SF61	FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA	FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA	catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;cis-trans isomerase activity#GO:0016859;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853			chaperone#PC00072	
ECOLI|EnsemblGenome=b4379|UniProtKB=P39409	P39409	yjjW	PTHR30352:SF13	PYRUVATE FORMATE-LYASE-ACTIVATING ENZYME	GLYCYL-RADICAL ENZYME ACTIVATING ENZYME YJJW-RELATED	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491				
ECOLI|EnsemblGenome=b3795|UniProtKB=P27837	P27837	thrP	PTHR43495:SF7	GABA PERMEASE	THREONINE_SERINE TRANSPORTER THRP	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227;secondary carrier transporter#PC00258;amino acid transporter#PC00046	
ECOLI|EnsemblGenome=b1127|UniProtKB=P29745	P29745	pepT	PTHR42994:SF1	PEPTIDASE T	PEPTIDASE T	aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238	peptide metabolic process#GO:0006518;cellular process#GO:0009987;metabolic process#GO:0008152	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	protease#PC00190;metalloprotease#PC00153	
ECOLI|EnsemblGenome=b3987|UniProtKB=P0A8V2	P0A8V2	rpoB	PTHR20856:SF34	DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA	catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640	DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070	transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;cytosol#GO:0005829;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737	RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019	
ECOLI|EnsemblGenome=b0365|UniProtKB=Q47537	Q47537	tauA	PTHR30024:SF47	ALIPHATIC SULFONATES-BINDING PROTEIN-RELATED	TAURINE-BINDING PERIPLASMIC PROTEIN		cellular response to stress#GO:0033554;cellular response to nutrient levels#GO:0031669;cellular response to starvation#GO:0009267;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to nutrient levels#GO:0031667;response to starvation#GO:0042594;response to stress#GO:0006950;response to stimulus#GO:0050896			
ECOLI|EnsemblGenome=b3178|UniProtKB=P0AAI3	P0AAI3	ftsH	PTHR23076:SF145	METALLOPROTEASE M41 FTSH	ATP-DEPENDENT ZINC METALLOPROTEASE FTSH	peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824	catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	metalloprotease#PC00153	
ECOLI|EnsemblGenome=b1335|UniProtKB=P0AFH0	P0AFH0	ogt	PTHR10815:SF5	METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE	METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE				DNA methyltransferase#PC00013;DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b1281|UniProtKB=P08244	P08244	pyrF	PTHR32119:SF2	OROTIDINE 5'-PHOSPHATE DECARBOXYLASE	OROTIDINE 5'-PHOSPHATE DECARBOXYLASE	lyase activity#GO:0016829;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830	biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;pyrimidine-containing compound metabolic process#GO:0072527;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;pyrimidine nucleobase metabolic process#GO:0006206;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	decarboxylase#PC00089;lyase#PC00144;metabolite interconversion enzyme#PC00262	De novo pyrimidine ribonucleotides biosythesis#P02740>Orotidine-5-phosphate decarboxylase#P02930
ECOLI|EnsemblGenome=b1900|UniProtKB=P0AAF3	P0AAF3	araG	PTHR43790:SF6	CARBOHYDRATE TRANSPORT ATP-BINDING PROTEIN MG119-RELATED	ARABINOSE IMPORT ATP-BINDING PROTEIN ARAG	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b0641|UniProtKB=P0ADC1	P0ADC1	lptE	PTHR38098:SF2	LPS-ASSEMBLY LIPOPROTEIN LPTE	LPS-ASSEMBLY LIPOPROTEIN LPTE	lipid binding#GO:0008289;lipopolysaccharide binding#GO:0001530;binding#GO:0005488;carbohydrate derivative binding#GO:0097367	macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;membrane assembly#GO:0071709;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;lipid transport#GO:0006869;cellular component assembly#GO:0022607;membrane organization#GO:0061024;lipid localization#GO:0010876;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;external encapsulating structure organization#GO:0045229	extracellular region#GO:0005576;outer membrane#GO:0019867;transporter complex#GO:1990351;cell outer membrane#GO:0009279;membrane#GO:0016020;external encapsulating structure#GO:0030312;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313		
ECOLI|EnsemblGenome=b2875|UniProtKB=Q46808	Q46808	yqeB	PTHR30388:SF6	ALDEHYDE OXIDOREDUCTASE MOLYBDENUM COFACTOR ASSEMBLY PROTEIN	XANTHINE DEHYDROGENASE SUBUNIT A-RELATED				chaperone#PC00072	
ECOLI|EnsemblGenome=b0442|UniProtKB=P0AAR8	P0AAR8	ybaV	PTHR21180:SF32	ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1	COME OPERON PROTEIN 1					
ECOLI|EnsemblGenome=b2984|UniProtKB=P64572	P64572	yghR	PTHR10344:SF4	THYMIDYLATE KINASE	THYMIDYLATE KINASE	phosphotransferase activity, phosphate group as acceptor#GO:0016776;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824	nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleoside diphosphate metabolic process#GO:0009132	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	nucleotide kinase#PC00172;kinase#PC00137;transferase#PC00220	De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTMP kinase#P02916
ECOLI|EnsemblGenome=b3704|UniProtKB=P0A7Y8	P0A7Y8	rnpA	PTHR33992:SF1	RIBONUCLEASE P PROTEIN COMPONENT	RIBONUCLEASE P PROTEIN COMPONENT	catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;ribonuclease P activity#GO:0004526;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101	RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;tRNA 3'-end processing#GO:0042780;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA processing#GO:0008033;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654	ribonucleoprotein complex#GO:1990904;ribonuclease P complex#GO:0030677;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535	endoribonuclease#PC00094	
ECOLI|EnsemblGenome=b3653|UniProtKB=P0AER8	P0AER8	gltS	PTHR36178:SF1	SLR0625 PROTEIN	SODIUM_GLUTAMATE SYMPORTER	solute:monoatomic cation symporter activity#GO:0015294;dicarboxylic acid transmembrane transporter activity#GO:0005310;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;transmembrane transporter activity#GO:0022857;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293	L-glutamate import#GO:0051938;localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;L-alpha-amino acid transmembrane transport#GO:1902475;carboxylic acid transmembrane transport#GO:1905039;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;amino acid transport#GO:0006865;acidic amino acid transport#GO:0015800;establishment of localization#GO:0051234;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;L-glutamate transmembrane transport#GO:0015813;dicarboxylic acid transport#GO:0006835	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	primary active transporter#PC00068	
ECOLI|EnsemblGenome=b3774|UniProtKB=P05793	P05793	ilvC	PTHR21371:SF28	KETOL-ACID REDUCTOISOMERASE, MITOCHONDRIAL	KETOL-ACID REDUCTOISOMERASE (NADP(+))	oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824	biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;proteinogenic amino acid biosynthetic process#GO:0170038;branched-chain amino acid biosynthetic process#GO:0009082;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		Valine biosynthesis#P02785>Dihydroxy isovalerate reductoisomerase#P03217;Isoleucine biosynthesis#P02748>Ketol-acid reductoisomerase#P02996
ECOLI|EnsemblGenome=b2216|UniProtKB=P39838	P39838	rcsD	PTHR43047:SF83	TWO-COMPONENT HISTIDINE PROTEIN KINASE	PHOSPHOTRANSFERASE RCSD	protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphorelay sensor kinase activity#GO:0000155;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;protein histidine kinase activity#GO:0004673	intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;phosphorelay signal transduction system#GO:0000160;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	histidine kinase receptor of two-component system#PC00265	
ECOLI|EnsemblGenome=b3051|UniProtKB=P77306	P77306	yqiK	PTHR13806:SF48	FLOTILLIN-RELATED	FLOTILLIN FAMILY INNER MEMBRANE PROTEIN YQIK			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b0387|UniProtKB=P0A8D3	P0A8D3	yaiI	PTHR35146:SF1	UPF0178 PROTEIN YAII	UPF0178 PROTEIN YAII					
ECOLI|EnsemblGenome=b0147|UniProtKB=P37025	P37025	thpR	PTHR35561:SF1	RNA 2',3'-CYCLIC PHOSPHODIESTERASE	RNA 2',3'-CYCLIC PHOSPHODIESTERASE	catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112			RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b0054|UniProtKB=P31554	P31554	lptD	PTHR30189:SF1	LPS-ASSEMBLY PROTEIN	LPS-ASSEMBLY PROTEIN LPTD			external encapsulating structure#GO:0030312;cell outer membrane#GO:0009279;membrane#GO:0016020;cell envelope#GO:0030313;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;outer membrane#GO:0019867;extracellular region#GO:0005576;transporter complex#GO:1990351		
ECOLI|EnsemblGenome=b1221|UniProtKB=P0AF28	P0AF28	narL	PTHR43214:SF38	TWO-COMPONENT RESPONSE REGULATOR	NITRATE_NITRITE RESPONSE REGULATOR PROTEIN NARL	DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355		helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b4388|UniProtKB=P0AGB0	P0AGB0	serB	PTHR43344:SF2	PHOSPHOSERINE PHOSPHATASE	PHOSPHOSERINE PHOSPHATASE	hydrolase activity#GO:0016787;metal ion binding#GO:0046872;cation binding#GO:0043169;magnesium ion binding#GO:0000287;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788	cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;phosphatase#PC00181	Serine glycine biosynthesis#P02776>Phosphoserine phosphatase#P03159
ECOLI|EnsemblGenome=b3880|UniProtKB=P32140	P32140	yihS	PTHR15108:SF1	N-ACYLGLUCOSAMINE-2-EPIMERASE	SULFOQUINOVOSE ISOMERASE	racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853	metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;catabolic process#GO:0009056;sulfur compound catabolic process#GO:0044273;carbohydrate derivative catabolic process#GO:1901136		epimerase/racemase#PC00096	
ECOLI|EnsemblGenome=b1947|UniProtKB=P22586	P22586	fliO	PTHR38766:SF1	FLAGELLAR PROTEIN FLIO	FLAGELLAR PROTEIN FLIO				structural protein#PC00211	
ECOLI|EnsemblGenome=b1844|UniProtKB=P0AEK0	P0AEK0	exoX	PTHR30231:SF37	DNA POLYMERASE III SUBUNIT EPSILON	EXODEOXYRIBONUCLEASE 10	hydrolase activity, acting on ester bonds#GO:0016788;exonuclease activity#GO:0004527;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;3'-5' exonuclease activity#GO:0008408;hydrolase activity#GO:0016787	macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b1467|UniProtKB=P19318	P19318	narY	PTHR43518:SF3	NITRATE REDUCTASE BETA SUBUNIT	RESPIRATORY NITRATE REDUCTASE 2 BETA CHAIN	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;anaerobic electron transport chain#GO:0019645;anaerobic respiration#GO:0009061	cellular anatomical structure#GO:0110165;membrane#GO:0016020	metabolite interconversion enzyme#PC00262;reductase#PC00198	
ECOLI|EnsemblGenome=b0740|UniProtKB=P0A855	P0A855	tolB	PTHR42972:SF14	TOL-PAL SYSTEM PROTEIN TOLB	TOL-PAL SYSTEM PROTEIN TOLB		cellular component organization#GO:0016043;cell cycle#GO:0007049;cell septum assembly#GO:0090529;cell division#GO:0051301;cell cycle process#GO:0022402;localization#GO:0051179;protein transport#GO:0015031;cytokinesis#GO:0000910;cytokinetic process#GO:0032506;cellular component assembly#GO:0022607;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;transport#GO:0006810		secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b0709|UniProtKB=P75742	P75742	dtpD	PTHR11654:SF119	OLIGOPEPTIDE TRANSPORTER-RELATED	DIPEPTIDE PERMEASE D	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b0774|UniProtKB=P12995	P12995	bioA	PTHR42684:SF17	ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE	ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;transaminase activity#GO:0008483	monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;biotin metabolic process#GO:0006768;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790		transaminase#PC00216	Biotin biosynthesis#P02731>Adenosylmethionine-8-amino-7-oxononanoate aminotransferase#P02856
ECOLI|EnsemblGenome=b0414|UniProtKB=P25539	P25539	ribD	PTHR11079:SF162	CYTOSINE DEAMINASE FAMILY MEMBER	RIBOFLAVIN BIOSYNTHESIS PROTEIN PYRD, CHLOROPLASTIC-RELATED	hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;catalytic activity#GO:0003824			hydrolase#PC00121;metabolite interconversion enzyme#PC00262;deaminase#PC00088	Flavin biosynthesis#P02741>Pyrimidine deaminase#P02933
ECOLI|EnsemblGenome=b4309|UniProtKB=P39370	P39370	nanS	PTHR31988:SF15	ESTERASE, PUTATIVE (DUF303)-RELATED	ESTERASE, PUTATIVE (DUF303)-RELATED	hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787	small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987		metabolite interconversion enzyme#PC00262;esterase#PC00097;hydrolase#PC00121	
ECOLI|EnsemblGenome=b1946|UniProtKB=P15070	P15070	fliN	PTHR43484:SF1	FLAGELLAR MOTOR SWITCH PROTEIN FLIN	FLAGELLAR MOTOR SWITCH PROTEIN FLIN	phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824	regulation of biological process#GO:0050789;regulation of cell motility#GO:2000145;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of locomotion#GO:0040012			
ECOLI|EnsemblGenome=b0099|UniProtKB=P08337	P08337	mutT	PTHR47707:SF1	8-OXO-DGTP DIPHOSPHATASE	8-OXO-DGTP DIPHOSPHATASE	hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110;nucleoside triphosphate diphosphatase activity#GO:0047429;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817	response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170		phosphatase#PC00181;hydrolase#PC00121	
ECOLI|EnsemblGenome=b1320|UniProtKB=P77615	P77615	ycjW	PTHR30146:SF109	LACI-RELATED TRANSCRIPTIONAL REPRESSOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR GALS-RELATED	DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252		helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218;Lambda repressor-like transcription factor#PC00245	
ECOLI|EnsemblGenome=b4057|UniProtKB=P0AF50	P0AF50	yjbR	PTHR35145:SF3	CYTOPLASMIC PROTEIN-RELATED	CYTOPLASMIC PROTEIN					
ECOLI|Gene_OrderedLocusName=JW3998|UniProtKB=P32690	P32690	yjbI	PTHR14136:SF17	BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9	BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9					
ECOLI|EnsemblGenome=b2965|UniProtKB=P21169	P21169	speC	PTHR45229:SF4	CONSTITUTIVE ORNITHINE DECARBOXYLASE	CONSTITUTIVE ORNITHINE DECARBOXYLASE	ornithine decarboxylase activity#GO:0004586;lyase activity#GO:0016829;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831		cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	decarboxylase#PC00089;metabolite interconversion enzyme#PC00262;lyase#PC00144	
ECOLI|EnsemblGenome=b1226|UniProtKB=P0AF26	P0AF26	narJ	PTHR43680:SF2	NITRATE REDUCTASE MOLYBDENUM COFACTOR ASSEMBLY CHAPERONE	NITRATE REDUCTASE MOLYBDENUM COFACTOR ASSEMBLY CHAPERONE NARJ	molecular carrier activity#GO:0140104	small molecule metabolic process#GO:0044281;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;nitrate metabolic process#GO:0042126;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;chaperone-mediated protein complex assembly#GO:0051131		chaperone#PC00072	
ECOLI|EnsemblGenome=b4403|UniProtKB=P37005	P37005	lasT	PTHR42786:SF1	TRNA/RRNA METHYLTRANSFERASE	TRNA (CYTIDINE_URIDINE-2'-O-)-METHYLTRANSFERASE TRMJ		cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;methylation#GO:0032259	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	RNA methyltransferase#PC00033;RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b3832|UniProtKB=P0AG71	P0AG71	rmuC	PTHR30563:SF0	DNA RECOMBINATION PROTEIN RMUC	DNA RECOMBINATION PROTEIN RMUC		nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259		DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b1243|UniProtKB=P23843	P23843	oppA	PTHR30290:SF86	PERIPLASMIC BINDING COMPONENT OF ABC TRANSPORTER	PERIPLASMIC OLIGOPEPTIDE-BINDING PROTEIN OPPA-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	establishment of localization#GO:0051234;localization#GO:0051179;peptide transport#GO:0015833;transport#GO:0006810	cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;extracellular region#GO:0005576;periplasmic space#GO:0042597	transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0835|UniProtKB=P0AEI4	P0AEI4	rimO	PTHR43837:SF1	RIBOSOMAL PROTEIN S12 METHYLTHIOTRANSFERASE RIMO	RIBOSOMAL PROTEIN US12 METHYLTHIOTRANSFERASE RIMO	catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;iron-sulfur cluster binding#GO:0051536		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	protein modifying enzyme#PC00260	
ECOLI|EnsemblGenome=b0885|UniProtKB=P0A8P1	P0A8P1	aat	PTHR30098:SF2	LEUCYL/PHENYLALANYL-TRNA--PROTEIN TRANSFERASE	LEUCYL_PHENYLALANYL-TRNA--PROTEIN TRANSFERASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity#GO:0016746;catalytic activity, acting on a tRNA#GO:0140101		intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	translational protein#PC00263	
ECOLI|EnsemblGenome=b1453|UniProtKB=P77610	P77610	ansP	PTHR43495:SF1	GABA PERMEASE	L-ASPARAGINE PERMEASE	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227;secondary carrier transporter#PC00258;amino acid transporter#PC00046	
ECOLI|EnsemblGenome=b2900|UniProtKB=P67603	P67603	yqfB	PTHR38088:SF2	UCP029143 FAMILY PROTEIN	N(4)-ACETYLCYTIDINE AMIDOHYDROLASE			intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b3621|UniProtKB=P24173	P24173	waaC	PTHR30160:SF19	TETRAACYLDISACCHARIDE 4'-KINASE-RELATED	LIPOPOLYSACCHARIDE HEPTOSYLTRANSFERASE 1	transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757	polysaccharide biosynthetic process#GO:0000271;oligosaccharide biosynthetic process#GO:0009312;lipopolysaccharide metabolic process#GO:0008653;primary metabolic process#GO:0044238;lipopolysaccharide biosynthetic process#GO:0009103;lipopolysaccharide core region biosynthetic process#GO:0009244;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;liposaccharide metabolic process#GO:1903509;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oligosaccharide metabolic process#GO:0009311;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	kinase#PC00137;carbohydrate kinase#PC00065	
ECOLI|EnsemblGenome=b2711|UniProtKB=P37596	P37596	norW	PTHR43031:SF7	FAD-DEPENDENT OXIDOREDUCTASE	NITRIC OXIDE REDUCTASE FLRD-NAD(+) REDUCTASE	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2745|UniProtKB=Q57261	Q57261	truD	PTHR47811:SF1	TRNA PSEUDOURIDINE SYNTHASE D	TRNA PSEUDOURIDINE SYNTHASE D	isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824	metabolic process#GO:0008152;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;pseudouridine synthesis#GO:0001522;nucleobase-containing compound metabolic process#GO:0006139	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	RNA metabolism protein#PC00031;RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b2817|UniProtKB=P63883	P63883	amiC	PTHR30404:SF0	N-ACETYLMURAMOYL-L-ALANINE AMIDASE	N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMIC	N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787	cell cycle#GO:0007049;cellular process#GO:0009987;cell division#GO:0051301;cell cycle process#GO:0022402;reproductive process in single-celled organism#GO:0022413;reproductive process#GO:0022414;FtsZ-dependent cytokinesis#GO:0043093;cytokinesis#GO:0000910	cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313;extracellular region#GO:0005576;periplasmic space#GO:0042597	hydrolase#PC00121	
ECOLI|EnsemblGenome=b2782|UniProtKB=P0AE70	P0AE70	mazF	PTHR33988:SF3	ENDORIBONUCLEASE MAZF-RELATED	ENDORIBONUCLEASE TOXIN CHPB-RELATED	catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640	regulation of biological process#GO:0050789;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;macromolecule catabolic process#GO:0009057;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170		endoribonuclease#PC00094	
ECOLI|EnsemblGenome=b2548|UniProtKB=P77269	P77269	yphF	PTHR30036:SF7	D-XYLOSE-BINDING PERIPLASMIC PROTEIN	ABC TRANSPORTER PERIPLASMIC-BINDING PROTEIN YPHF	binding#GO:0005488;carbohydrate binding#GO:0030246		outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;periplasmic space#GO:0042597;extracellular region#GO:0005576		
ECOLI|EnsemblGenome=b3563|UniProtKB=P11286	P11286	yiaB	PTHR37290:SF2	INNER MEMBRANE PROTEIN YIAA-RELATED	INNER MEMBRANE PROTEIN YIAB		response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b3469|UniProtKB=P37617	P37617	zntA	PTHR48085:SF16	CADMIUM/ZINC-TRANSPORTING ATPASE HMA2-RELATED	ZINC_CADMIUM_LEAD-TRANSPORTING P-TYPE ATPASE	metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transition metal ion transmembrane transporter activity#GO:0046915	metal ion transport#GO:0030001;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810	cellular anatomical structure#GO:0110165;membrane#GO:0016020		
ECOLI|EnsemblGenome=b0415|UniProtKB=P61714	P61714	ribE	PTHR21058:SF2	6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE  DMRL SYNTHASE   LUMAZINE SYNTHASE	6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE	transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740	flavin-containing compound metabolic process#GO:0042726;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	transferase#PC00220	Flavin biosynthesis#P02741>Lumazine synthase#P02939
ECOLI|EnsemblGenome=b4401|UniProtKB=P0A9Q1	P0A9Q1	arcA	PTHR48111:SF55	REGULATOR OF RPOS	AEROBIC RESPIRATION CONTROL PROTEIN ARCA	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;molecular transducer activity#GO:0060089;double-stranded DNA binding#GO:0003690	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993	helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b4280|UniProtKB=P39353	P39353	nanY	PTHR43377:SF1	BILIVERDIN REDUCTASE A	BILIVERDIN REDUCTASE A				dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b3511|UniProtKB=P0AET5	P0AET5	hdeD	PTHR34989:SF1	PROTEIN HDED	PROTEIN HDED			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b1539|UniProtKB=P39831	P39831	ydfG	PTHR43086:SF5	VERY-LONG-CHAIN 3-OXOOACYL-COA REDUCTASE	NADP-DEPENDENT 3-HYDROXY ACID DEHYDROGENASE YDFG			cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	oxidoreductase#PC00176;reductase#PC00198	
ECOLI|EnsemblGenome=b2572|UniProtKB=P0AFX7	P0AFX7	rseA	PTHR38104:SF1	ANTI-SIGMA-E FACTOR RSEA	ANTI-SIGMA-E FACTOR RSEA	transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712				
ECOLI|EnsemblGenome=b3149|UniProtKB=P66817	P66817	diaA	PTHR30390:SF6	SEDOHEPTULOSE 7-PHOSPHATE ISOMERASE / DNAA INITIATOR-ASSOCIATING FACTOR FOR REPLICATION INITIATION	DNAA INITIATOR-ASSOCIATING PROTEIN DIAA		regulation of DNA replication#GO:0006275;positive regulation of metabolic process#GO:0009893;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of DNA metabolic process#GO:0051054;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of DNA-templated DNA replication initiation#GO:0030174;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of DNA replication#GO:0045740;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518	replisome#GO:0030894;replication fork#GO:0005657;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228		
ECOLI|EnsemblGenome=b2494|UniProtKB=P66948	P66948	bepA	PTHR22726:SF27	METALLOENDOPEPTIDASE OMA1	BETA-BARREL ASSEMBLY-ENHANCING PROTEASE	catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175	catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163	membrane#GO:0016020;cellular anatomical structure#GO:0110165	protease#PC00190;metalloprotease#PC00153;protein modifying enzyme#PC00260	
ECOLI|EnsemblGenome=b0140|UniProtKB=P33128	P33128	yadV	PTHR30251:SF2	PILUS ASSEMBLY CHAPERONE	FIMBRIAL CHAPERONE YADV-RELATED		protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238	cell envelope#GO:0030313;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;periplasmic space#GO:0042597;extracellular region#GO:0005576	chaperone#PC00072	
ECOLI|EnsemblGenome=b0124|UniProtKB=P15877	P15877	gcd	PTHR32303:SF4	QUINOPROTEIN ALCOHOL DEHYDROGENASE (CYTOCHROME C)	QUINOPROTEIN GLUCOSE DEHYDROGENASE			membrane#GO:0016020;cellular anatomical structure#GO:0110165	dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b4053|UniProtKB=P0A6B4	P0A6B4	alr	PTHR30511:SF4	ALANINE RACEMASE	ALANINE RACEMASE, BIOSYNTHETIC	isomerase activity#GO:0016853;heterocyclic compound binding#GO:1901363;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167	amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	epimerase/racemase#PC00096	
ECOLI|EnsemblGenome=b0081|UniProtKB=P22186	P22186	mraZ	PTHR34701:SF1	TRANSCRIPTIONAL REGULATOR MRAZ	TRANSCRIPTIONAL REGULATOR MRAZ	nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription initiation#GO:2000142;negative regulation of biological process#GO:0048519		gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b3878|UniProtKB=P32138	P32138	yihQ	PTHR46959:SF3	SULFOQUINOVOSIDASE	SULFOQUINOVOSIDASE	catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798				
ECOLI|EnsemblGenome=b0468|UniProtKB=P0AAR5	P0AAR5	ybaN	PTHR35813:SF1	INNER MEMBRANE PROTEIN YBAN	INNER MEMBRANE PROTEIN YBAN			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b2797|UniProtKB=P30744	P30744	sdaB	PTHR30182:SF14	L-SERINE DEHYDRATASE	L-SERINE DEHYDRATASE 2	lyase activity#GO:0016829;catalytic activity#GO:0003824	oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056		lyase#PC00144;dehydratase#PC00091	
ECOLI|EnsemblGenome=b4020|UniProtKB=P0AF43	P0AF43	yjbB	PTHR10010:SF39	SOLUTE CARRIER FAMILY 34  SODIUM PHOSPHATE , MEMBER 2-RELATED	INORGANIC PHOSPHATE EXPORT PROTEIN YJBB-RELATED				secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b0869|UniProtKB=P75822	P75822	ybjT	PTHR43000:SF12	DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED	NAD(P)-BINDING PROTEIN YBJT-RELATED				dehydratase#PC00091	
ECOLI|EnsemblGenome=b0438|UniProtKB=P0A6H1	P0A6H1	clpX	PTHR48102:SF18	ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED	ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX	hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;ATP-dependent activity#GO:0140657;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817	primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538		protease#PC00190	
ECOLI|EnsemblGenome=b2673|UniProtKB=P0AC65	P0AC65	nrdH	PTHR34386:SF1	GLUTAREDOXIN	GLUTAREDOXIN-LIKE PROTEIN NRDH		cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592		metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0642|UniProtKB=P07813	P07813	leuS	PTHR43740:SF2	LEUCYL-TRNA SYNTHETASE	LEUCINE--TRNA LIGASE, CHLOROPLASTIC_MITOCHONDRIAL	catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874	translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467		aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263	
ECOLI|EnsemblGenome=b0941|UniProtKB=P75858	P75858	elfG	PTHR33420:SF31	FIMBRIAL SUBUNIT ELFA-RELATED	PROTEIN LPFD		cell-substrate adhesion#GO:0031589;single-species biofilm formation#GO:0044010;cell adhesion#GO:0007155;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;cell projection#GO:0042995		
ECOLI|EnsemblGenome=b3185|UniProtKB=P0A7L8	P0A7L8	rpmA	PTHR15893:SF0	RIBOSOMAL PROTEIN L27	LARGE RIBOSOMAL SUBUNIT PROTEIN BL27	structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198	macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170		ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b1518|UniProtKB=P64461	P64461	lsrG	PTHR33336:SF1	QUINOL MONOOXYGENASE YGIN-RELATED	(4S)-4-HYDROXY-5-PHOSPHONOOXYPENTANE-2,3-DIONE ISOMERASE	intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861			oxygenase#PC00177	
ECOLI|EnsemblGenome=b2458|UniProtKB=P77218	P77218	eutD	PTHR43356:SF1	PHOSPHATE ACETYLTRANSFERASE	PHOSPHATE ACETYLTRANSFERASE EUTD	transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746			acetyltransferase#PC00038;transferase#PC00220	Acetate utilization#P02722>Phosphate acetyltransferase#P02802
ECOLI|EnsemblGenome=b4332|UniProtKB=P39381	P39381	yjiJ	PTHR23537:SF1	FAMILY NOT NAMED	SUGAR TRANSPORTER			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2434|UniProtKB=P76539	P76539	ypeA	PTHR43420:SF12	ACETYLTRANSFERASE	N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN	N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747			acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262	
ECOLI|Gene_OrderedLocusName=b4490|UniProtKB=P75901	P75901	efeU	PTHR31632:SF8	IRON TRANSPORTER FTH1	INACTIVE FERROUS IRON PERMEASE EFEU-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;iron ion transmembrane transporter activity#GO:0005381	monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;iron ion transmembrane transport#GO:0034755;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;transport#GO:0006810;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b2318|UniProtKB=P07649	P07649	truA	PTHR11142:SF0	PSEUDOURIDYLATE SYNTHASE	TRNA PSEUDOURIDINE SYNTHASE	isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;intramolecular transferase activity#GO:0016866	gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;mRNA modification#GO:0016556;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;pseudouridine synthesis#GO:0001522;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451		lyase#PC00144	
ECOLI|EnsemblGenome=b3355|UniProtKB=P0AEX5	P0AEX5	prkB	PTHR10285:SF209	URIDINE KINASE	PHOSPHORIBULOKINASE, CHLOROPLASTIC			cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	kinase#PC00137;nucleotide kinase#PC00172	Pentose phosphate pathway#P02762>D-Ribulo Kinase#P03077
ECOLI|EnsemblGenome=b1968|UniProtKB=P76339	P76339	hprS	PTHR45436:SF3	SENSOR HISTIDINE KINASE YKOH	SENSOR HISTIDINE KINASE HPRS		cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;phosphorelay signal transduction system#GO:0000160;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transmembrane signal receptor#PC00197;histidine kinase receptor of two-component system#PC00265	
ECOLI|EnsemblGenome=b2374|UniProtKB=P69902	P69902	frc	PTHR48228:SF5	SUCCINYL-COA--D-CITRAMALATE COA-TRANSFERASE	FORMYL-COA:OXALATE COA-TRANSFERASE				transferase#PC00220;metabolite interconversion enzyme#PC00262	Carnitine metabolism#P02733>Carnitine dehydratase#P02866
ECOLI|EnsemblGenome=b0028|UniProtKB=P0AEM0	P0AEM0	fkpB	PTHR47861:SF4	FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD	FKBP-TYPE 16 KDA PEPTIDYL-PROLYL CIS-TRANS ISOMERASE	cis-trans isomerase activity#GO:0016859;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824	metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein refolding#GO:0042026;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	chaperone#PC00072	
ECOLI|EnsemblGenome=b4171|UniProtKB=P16384	P16384	miaA	PTHR11088:SF60	TRNA DIMETHYLALLYLTRANSFERASE	TRNA DIMETHYLALLYLTRANSFERASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098	RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396		RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b3104|UniProtKB=P64592	P64592	yhaI	PTHR34980:SF2	INNER MEMBRANE PROTEIN-RELATED-RELATED	INNER MEMBRANE PROTEIN YHAH-RELATED			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b4220|UniProtKB=P0ADE4	P0ADE4	tamA	PTHR12815:SF58	SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER	TRANSLOCATION AND ASSEMBLY MODULE SUBUNIT TAMA		cellular process#GO:0009987;protein localization to extracellular region#GO:0071692;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;export from cell#GO:0140352;transport#GO:0006810;protein transport#GO:0015031;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;secretion by cell#GO:0032940;secretion#GO:0046903;establishment of localization#GO:0051234;protein secretion#GO:0009306;localization#GO:0051179	extracellular region#GO:0005576;outer membrane#GO:0019867;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;external encapsulating structure#GO:0030312;membrane#GO:0016020;cell outer membrane#GO:0009279		
ECOLI|EnsemblGenome=b1817|UniProtKB=P69797	P69797	manX	PTHR33799:SF1	PTS PERMEASE-RELATED-RELATED	PTS SYSTEM MANNOSE-SPECIFIC EIIAB COMPONENT-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;active transmembrane transporter activity#GO:0022804;carbohydrate transmembrane transporter activity#GO:0015144;phosphotransferase activity, alcohol group as acceptor#GO:0016773	import across plasma membrane#GO:0098739;carbohydrate transmembrane transport#GO:0034219;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;import into cell#GO:0098657;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;carbohydrate transport#GO:0008643;transport#GO:0006810	membrane#GO:0016020;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;transporter complex#GO:1990351;cellular anatomical structure#GO:0110165;transmembrane transporter complex#GO:1902495		
ECOLI|EnsemblGenome=b2186|UniProtKB=P33920	P33920	yejK	PTHR38772:SF1	NUCLEOID-ASSOCIATED PROTEIN YEJK	NUCLEOID-ASSOCIATED PROTEIN YEJK	double-stranded DNA binding#GO:0003690;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676		intracellular anatomical structure#GO:0005622;bacterial nucleoid#GO:0043590;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;nucleoid#GO:0009295;organelle#GO:0043226;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2593|UniProtKB=P33644	P33644	pgeF	PTHR30616:SF2	UNCHARACTERIZED PROTEIN YFIH	PEPTIDOGLYCAN EDITING FACTOR PGEF	hydrolase activity#GO:0016787;adenosine deaminase activity#GO:0004000;pentosyltransferase activity#GO:0016763;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;glycosyltransferase activity#GO:0016757;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;transferase activity#GO:0016740;catalytic activity#GO:0003824	biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222			
ECOLI|EnsemblGenome=b1329|UniProtKB=P77348	P77348	mppA	PTHR30290:SF23	PERIPLASMIC BINDING COMPONENT OF ABC TRANSPORTER	PERIPLASMIC MUREIN PEPTIDE-BINDING PROTEIN MPPA	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;peptide transport#GO:0015833	extracellular region#GO:0005576;periplasmic space#GO:0042597;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313	ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227	
ECOLI|EnsemblGenome=b2060|UniProtKB=P76387	P76387	wzc	PTHR32309:SF32	TYROSINE-PROTEIN KINASE	TYROSINE-PROTEIN KINASE ETK-RELATED	transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	non-receptor tyrosine protein kinase#PC00168	
ECOLI|EnsemblGenome=b3601|UniProtKB=P0AF10	P0AF10	mtlR	PTHR37941:SF1	FUMARASE E-RELATED	FUMARASE E-RELATED		negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892			
ECOLI|EnsemblGenome=b0126|UniProtKB=P61517	P61517	can	PTHR11002:SF82	CARBONIC ANHYDRASE	CARBONIC ANHYDRASE		response to nutrient levels#GO:0031667;response to stimulus#GO:0050896		dehydratase#PC00091;lyase#PC00144	
ECOLI|EnsemblGenome=b1547|UniProtKB=P77515	P77515	stfQ	PTHR35191:SF1	PROPHAGE SIDE TAIL FIBER PROTEIN HOMOLOG STFQ-RELATED	PROPHAGE SIDE TAIL FIBER PROTEIN HOMOLOG STFQ-RELATED					
ECOLI|EnsemblGenome=b0368|UniProtKB=P37610	P37610	tauD	PTHR30468:SF34	ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE	ALPHA-KETOGLUTARATE-DEPENDENT TAURINE DIOXYGENASE	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213	metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	oxidoreductase#PC00176;oxygenase#PC00177	
ECOLI|EnsemblGenome=b1886|UniProtKB=P07017	P07017	tar	PTHR43531:SF16	PROTEIN ICFG	METHYL-ACCEPTING CHEMOTAXIS PROTEIN II	transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023	chemotaxis#GO:0006935;response to stimulus#GO:0050896;taxis#GO:0042330;response to chemical#GO:0042221;locomotion#GO:0040011;response to external stimulus#GO:0009605	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b3186|UniProtKB=P0AG48	P0AG48	rplU	PTHR21349:SF9	50S RIBOSOMAL PROTEIN L21	LARGE RIBOSOMAL SUBUNIT PROTEIN BL21	structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198	macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987		ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b0144|UniProtKB=P27305	P27305	gluQ	PTHR43311:SF1	GLUTAMATE--TRNA LIGASE	GLUTAMYL-Q TRNA(ASP) SYNTHETASE	catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640	tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	aminoacyl-tRNA synthetase#PC00047	Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977
ECOLI|EnsemblGenome=b2242|UniProtKB=P13033	P13033	glpB	PTHR43400:SF13	FUMARATE REDUCTASE	ANAEROBIC GLYCEROL-3-PHOSPHATE DEHYDROGENASE SUBUNIT B	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614	metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;catabolic process#GO:0009056;anaerobic respiration#GO:0009061;carbohydrate derivative catabolic process#GO:1901136		oxidoreductase#PC00176;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b1126|UniProtKB=P69874	P69874	potA	PTHR42781:SF10	SPERMIDINE/PUTRESCINE IMPORT ATP-BINDING PROTEIN POTA	SPERMIDINE_PUTRESCINE IMPORT ATP-BINDING PROTEIN POTA	ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;polyamine transmembrane transporter activity#GO:0015203;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0067|UniProtKB=P31549	P31549	thiP	PTHR30183:SF9	MOLYBDENUM TRANSPORT SYSTEM PERMEASE PROTEIN MODB	THIAMINE TRANSPORT SYSTEM PERMEASE PROTEIN THIP	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b0640|UniProtKB=P28630	P28630	holA	PTHR34388:SF1	DNA POLYMERASE III SUBUNIT DELTA	DNA POLYMERASE III SUBUNIT DELTA		DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;cellular process#GO:0009987;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139	protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;transferase complex, transferring phosphorus-containing groups#GO:0061695;DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;catalytic complex#GO:1902494	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b2263|UniProtKB=P37355	P37355	menH	PTHR43248:SF31	2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE	2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE				hydrolase#PC00121	
ECOLI|EnsemblGenome=b3054|UniProtKB=P30871	P30871	ygiF	PTHR39569:SF1	INORGANIC TRIPHOSPHATASE	INORGANIC TRIPHOSPHATASE	catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787			phosphatase#PC00181	
ECOLI|EnsemblGenome=b3476|UniProtKB=P33590	P33590	nikA	PTHR30290:SF37	PERIPLASMIC BINDING COMPONENT OF ABC TRANSPORTER	NICKEL-BINDING PERIPLASMIC PROTEIN	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	transport#GO:0006810;peptide transport#GO:0015833;establishment of localization#GO:0051234;localization#GO:0051179	periplasmic space#GO:0042597;extracellular region#GO:0005576;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313	ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227	
ECOLI|EnsemblGenome=b2426|UniProtKB=P37440	P37440	ucpA	PTHR24321:SF8	DEHYDROGENASES, SHORT CHAIN	(3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED				metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b3319|UniProtKB=P60723	P60723	rplD	PTHR10746:SF6	50S RIBOSOMAL PROTEIN L4	LARGE RIBOSOMAL SUBUNIT PROTEIN UL4	structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735	post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255	intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular organelle#GO:0043229	ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b0040|UniProtKB=P31553	P31553	caiT	PTHR30047:SF11	HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN-RELATED	L-CARNITINE_GAMMA-BUTYROBETAINE ANTIPORTER	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0524|UniProtKB=P43341	P43341	lpxH	PTHR34990:SF1	UDP-2,3-DIACYLGLUCOSAMINE HYDROLASE-RELATED	UDP-2,3-DIACYLGLUCOSAMINE HYDROLASE	pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787	metabolic process#GO:0008152;lipid metabolic process#GO:0006629;carbohydrate derivative biosynthetic process#GO:1901137;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;lipid A biosynthetic process#GO:0009245;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644		hydrolase#PC00121	
ECOLI|EnsemblGenome=b3746|UniProtKB=P31473	P31473	ravA	PTHR32204:SF1	ATPASE RAVA	REGULATORY ATPASE RAVA	ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824		cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b3067|UniProtKB=P00579	P00579	rpoD	PTHR30603:SF60	RNA POLYMERASE SIGMA FACTOR RPO	RNA POLYMERASE SIGMA FACTOR RPOD	transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;catalytic activity, acting on RNA#GO:0140098;sequence-specific DNA binding#GO:0043565;transferase activity#GO:0016740;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772	biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889	transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991	helix-turn-helix transcription factor#PC00116;Sigma factor#PC00267	
ECOLI|EnsemblGenome=b3561|UniProtKB=P37669	P37669	wecH	PTHR40074:SF2	O-ACETYLTRANSFERASE WECH	O-ACETYLTRANSFERASE WECH	acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;catalytic activity#GO:0003824	biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975;carbohydrate biosynthetic process#GO:0016051;polysaccharide metabolic process#GO:0005976;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;polysaccharide biosynthetic process#GO:0000271;metabolic process#GO:0008152	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b0145|UniProtKB=P0ABS1	P0ABS1	dksA	PTHR33823:SF2	RNA POLYMERASE-BINDING TRANSCRIPTION FACTOR DKSA-RELATED	RNA POLYMERASE-BINDING TRANSCRIPTION FACTOR DKSA		biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355		DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b4109|UniProtKB=P0DM85	P0DM85	rdcA	PTHR43834:SF7	GTPASE DER	GTPASE DER-RELATED			cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	G-protein#PC00020	
ECOLI|EnsemblGenome=b1306|UniProtKB=P0AFN2	P0AFN2	pspC	PTHR33885:SF3	PHAGE SHOCK PROTEIN C	PHAGE SHOCK PROTEIN C			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b3433|UniProtKB=P0A9Q9	P0A9Q9	asd	PTHR46278:SF4	DEHYDROGENASE, PUTATIVE-RELATED	ASPARTATE-SEMIALDEHYDE DEHYDROGENASE	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;aspartate family amino acid biosynthetic process#GO:0009067;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;L-lysine biosynthetic process#GO:0009085;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0221|UniProtKB=Q47146	Q47146	fadE	PTHR48083:SF18	MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED	ACYL-COENZYME A DEHYDROGENASE	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627	catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid modification#GO:0030258;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b1707|UniProtKB=P76204	P76204	ydiV	PTHR33121:SF69	CYCLIC DI-GMP PHOSPHODIESTERASE PDEF	ANTI-FLHC(2)FLHD(4) FACTOR YDIV-RELATED	hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081	regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular process#GO:0050794	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185	
ECOLI|EnsemblGenome=b3234|UniProtKB=P39099	P39099	degQ	PTHR22939:SF101	SERINE PROTEASE FAMILY S1C HTRA-RELATED	PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ		protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987	extracellular region#GO:0005576;periplasmic space#GO:0042597;cellular anatomical structure#GO:0110165	serine protease#PC00203;protease#PC00190	
ECOLI|EnsemblGenome=b1771|UniProtKB=P77256	P77256	ydjG	PTHR43364:SF4	NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED	NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN				oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0543|UniProtKB=P23895	P23895	emrE	PTHR30561:SF25	SMR FAMILY PROTON-DEPENDENT DRUG EFFLUX TRANSPORTER SUGE	MULTIDRUG TRANSPORTER EMRE	active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297;quaternary ammonium group transmembrane transporter activity#GO:0015651	xenobiotic detoxification by transmembrane export across the plasma membrane#GO:1990961;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;quaternary ammonium group transport#GO:0015697;detoxification#GO:0098754;export from cell#GO:0140352;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;response to chemical#GO:0042221;transport#GO:0006810;xenobiotic transport#GO:0042908;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179	transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991	transporter#PC00227	
ECOLI|EnsemblGenome=b2415|UniProtKB=P0AA04	P0AA04	ptsH	PTHR33705:SF1	PHOSPHOCARRIER PROTEIN HPR	PHOSPHOCARRIER PROTEIN HPR				transfer/carrier protein#PC00219	
ECOLI|EnsemblGenome=b0901|UniProtKB=P43340	P43340	ycaK	PTHR10204:SF34	NAD P H OXIDOREDUCTASE-RELATED	NAD(P)H DEHYDROGENASE [QUINONE] 1	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;NAD(P)H dehydrogenase (quinone) activity#GO:0003955;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;catalytic activity#GO:0003824		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1247|UniProtKB=P77737	P77737	oppF	PTHR43776:SF16	TRANSPORT ATP-BINDING PROTEIN	D,D-DIPEPTIDE TRANSPORT ATP-BINDING PROTEIN DDPF-RELATED	carbohydrate derivative transmembrane transporter activity#GO:1901505;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b2176|UniProtKB=P76446	P76446	pdeN	PTHR33121:SF73	CYCLIC DI-GMP PHOSPHODIESTERASE PDEF	CYCLIC DI-GMP PHOSPHODIESTERASE PDEN-RELATED	phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824	biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121	
ECOLI|EnsemblGenome=b3370|UniProtKB=P45539	P45539	frlA	PTHR11785:SF512	AMINO ACID TRANSPORTER	B(0,+)-TYPE AMINO ACID TRANSPORTER 1	amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;L-amino acid transmembrane transporter activity#GO:0015179	transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;localization#GO:0051179;amino acid transport#GO:0006865;cellular process#GO:0009987;transport#GO:0006810	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b3030|UniProtKB=P20083	P20083	parE	PTHR45866:SF1	DNA GYRASE/TOPOISOMERASE SUBUNIT B	DNA TOPOISOMERASE 4 SUBUNIT B	ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853	nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;organelle organization#GO:0006996;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;metabolic process#GO:0008152	protein-containing complex#GO:0032991;catalytic complex#GO:1902494	DNA topoisomerase#PC00017;DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b4273|UniProtKB=P0CF58	P0CF58	insD6	PTHR37936:SF3	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b3462|UniProtKB=P0AC30	P0AC30	ftsX	PTHR47755:SF1	CELL DIVISION PROTEIN FTSX	CELL DIVISION PROTEIN FTSX		cellular process#GO:0009987;cell division#GO:0051301	membrane#GO:0016020;cell division site#GO:0032153;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2481|UniProtKB=P23481	P23481	hyfA	PTHR42859:SF16	OXIDOREDUCTASE	FORMATE HYDROGENLYASE SUBUNIT 2-RELATED				metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1077|UniProtKB=P75938	P75938	flgF	PTHR30435:SF18	FLAGELLAR PROTEIN	FLAGELLAR BASAL-BODY ROD PROTEIN FLGF		cell motility#GO:0048870;bacterial-type flagellum-dependent cell motility#GO:0071973;bacterial-type flagellum-dependent swarming motility#GO:0071978;archaeal or bacterial-type flagellum-dependent cell motility#GO:0097588;cellular process#GO:0009987;cilium or flagellum-dependent cell motility#GO:0001539	cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;bacterial-type flagellum#GO:0009288;cell projection#GO:0042995	structural protein#PC00211	
ECOLI|EnsemblGenome=b2418|UniProtKB=P40191	P40191	pdxK	PTHR10534:SF15	PYRIDOXAL KINASE	PYRIDOXINE_PYRIDOXAL_PYRIDOXAMINE KINASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773	organophosphate biosynthetic process#GO:0090407;small molecule biosynthetic process#GO:0044283;pyridine-containing compound metabolic process#GO:0072524;metabolic process#GO:0008152;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	kinase#PC00137	Pyridoxal phosphate salvage pathway#P02770>Pyridoxal kinase#P03121;Pyridoxal phosphate salvage pathway#P02770>Pyridoxamine kinase#P03122;Vitamin B6 metabolism#P02787>Pyridoxal kinase#P03244
ECOLI|EnsemblGenome=b3921|UniProtKB=P0AF34	P0AF34	yiiR	PTHR34980:SF1	INNER MEMBRANE PROTEIN-RELATED-RELATED	DUF805 DOMAIN-CONTAINING PROTEIN			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b2674|UniProtKB=P0A772	P0A772	nrdI	PTHR37297:SF1	PROTEIN NRDI	PROTEIN NRDI	ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553				
ECOLI|EnsemblGenome=b2470|UniProtKB=P24177	P24177	acrD	PTHR32063:SF32	SWARMING MOTILITY PROTEIN SWRC-RELATED	AMINOGLYCOSIDE EFFLUX PUMP-RELATED					
ECOLI|EnsemblGenome=b4192|UniProtKB=P39300	P39300	ulaG	PTHR43546:SF9	UPF0173 METAL-DEPENDENT HYDROLASE MJ1163-RELATED	L-ASCORBATE-6-PHOSPHATE LACTONASE ULAG-RELATED	catalytic activity#GO:0003824;hydrolase activity#GO:0016787			hydrolase#PC00121;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2126|UniProtKB=P0AD14	P0AD14	btsS	PTHR34220:SF10	SENSOR HISTIDINE KINASE YPDA	SENSOR HISTIDINE KINASE BTSS	molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;protein histidine kinase activity#GO:0004673;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphorelay sensor kinase activity#GO:0000155;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773	biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transmembrane signal receptor#PC00197;histidine kinase receptor of two-component system#PC00265	
ECOLI|EnsemblGenome=b0654|UniProtKB=P0AER3	P0AER3	gltJ	PTHR30614:SF42	MEMBRANE COMPONENT OF AMINO ACID ABC TRANSPORTER	GLUTAMATE_ASPARTATE IMPORT PERMEASE PROTEIN GLTJ	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171	establishment of localization#GO:0051234;localization#GO:0051179;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;transport#GO:0006810;acidic amino acid transport#GO:0015800;organic acid transport#GO:0015849;L-glutamate import#GO:0051938;dicarboxylic acid transport#GO:0006835;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	amino acid transporter#PC00046	
ECOLI|EnsemblGenome=b3360|UniProtKB=P00903	P00903	pabA	PTHR43418:SF17	MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN-RELATED	AMINODEOXYCHORISMATE SYNTHASE COMPONENT 2	transaminase activity#GO:0008483;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;transferase activity#GO:0016740;lyase activity#GO:0016829	tetrahydrofolate biosynthetic process#GO:0046654;oxoacid metabolic process#GO:0043436;tetrahydrofolate metabolic process#GO:0046653;indole-containing compound metabolic process#GO:0042430;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;aromatic amino acid biosynthetic process#GO:0009073;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;proteinogenic amino acid biosynthetic process#GO:0170038;cellular process#GO:0009987;amine metabolic process#GO:0009308;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;proteinogenic amino acid metabolic process#GO:0170039			Tryptophan biosynthesis#P02783>Anthranilate phosphoribosyl transferase#P03209;Tryptophan biosynthesis#P02783>Anthranilate synthase#P03206
ECOLI|EnsemblGenome=b0808|UniProtKB=P75783	P75783	ybiO	PTHR30460:SF0	MODERATE CONDUCTANCE MECHANOSENSITIVE CHANNEL YBIO	MODERATE CONDUCTANCE MECHANOSENSITIVE CHANNEL YBIO					
ECOLI|EnsemblGenome=b1759|UniProtKB=P77788	P77788	nudG	PTHR47707:SF2	8-OXO-DGTP DIPHOSPHATASE	CTP PYROPHOSPHOHYDROLASE	nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity#GO:0016787;nucleoside triphosphate diphosphatase activity#GO:0047429;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824	response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170		phosphatase#PC00181;hydrolase#PC00121	
ECOLI|EnsemblGenome=b2582|UniProtKB=P0AGG4	P0AGG4	trxC	PTHR45663:SF40	GEO12009P1	THIOREDOXIN 2	catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b4067|UniProtKB=P32705	P32705	actP	PTHR48086:SF6	SODIUM/PROLINE SYMPORTER-RELATED	CATION_ACETATE SYMPORTER ACTP	monocarboxylic acid transmembrane transporter activity#GO:0008028;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943	organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	primary active transporter#PC00068	
ECOLI|EnsemblGenome=b1303|UniProtKB=P37344	P37344	pspF	PTHR32071:SF38	TRANSCRIPTIONAL REGULATORY PROTEIN	PSP OPERON TRANSCRIPTIONAL ACTIVATOR	sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987	regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794	protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993	DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b1476|UniProtKB=P0AEK7	P0AEK7	fdnI	PTHR30074:SF5	FORMATE DEHYDROGENASE, NITRATE-INDUCIBLE, CYTOCHROME B556 FDN  SUBUNIT	FORMATE DEHYDROGENASE, NITRATE-INDUCIBLE, CYTOCHROME B556(FDN) SUBUNIT	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	anaerobic respiration#GO:0009061;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;cell periphery#GO:0071944;oxidoreductase complex#GO:1990204;membrane#GO:0016020	metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b2988|UniProtKB=P0AES0	P0AES0	gss	PTHR30094:SF18	BIFUNCTIONAL GLUTATHIONYLSPERMIDINE SYNTHETASE/AMIDASE-RELATED	BIFUNCTIONAL GLUTATHIONYLSPERMIDINE SYNTHETASE_AMIDASE	ligase activity, forming carbon-nitrogen bonds#GO:0016879;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;ligase activity#GO:0016874;catalytic activity#GO:0003824				
ECOLI|EnsemblGenome=b2820|UniProtKB=P08394	P08394	recB	PTHR11070:SF23	UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER	RECBCD ENZYME SUBUNIT RECB	ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853	macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA recombination#GO:0006310;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716	cytosol#GO:0005829;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b2942|UniProtKB=P0A817	P0A817	metK	PTHR11964:SF1	S-ADENOSYLMETHIONINE SYNTHETASE	S-ADENOSYLMETHIONINE SYNTHASE	transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824	biosynthetic process#GO:0009058;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	transferase#PC00220;nucleotidyltransferase#PC00174	S-adenosylmethionine biosynthesis#P02773>S-Adenosyl methionine synthetase#P03143
ECOLI|EnsemblGenome=b4469|UniProtKB=Q46861	Q46861	ygiQ	PTHR32331:SF0	UPF0313 PROTEIN YGIQ	UPF0313 PROTEIN YGIQ					
ECOLI|EnsemblGenome=b2249|UniProtKB=P77808	P77808	yfaY	PTHR13939:SF0	NICOTINAMIDE-NUCLEOTIDE AMIDOHYDROLASE PNCC	NMN AMIDOHYDROLASE-LIKE PROTEIN YFAY				hydrolase#PC00121;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2540|UniProtKB=P0ABW0	P0ABW0	hcaC	PTHR21496:SF23	FERREDOXIN-RELATED	3-PHENYLPROPIONATE_CINNAMIC ACID DIOXYGENASE FERREDOXIN SUBUNIT	iron-sulfur cluster binding#GO:0051536;small molecule binding#GO:0036094;binding#GO:0005488			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b4149|UniProtKB=P0A901	P0A901	blc	PTHR10612:SF34	APOLIPOPROTEIN D	LIPOCALIN_CYTOSOLIC FATTY-ACID BINDING DOMAIN-CONTAINING PROTEIN				apolipoprotein#PC00052	
ECOLI|EnsemblGenome=b4184|UniProtKB=P0AF80	P0AF80	yjfL	PTHR40043:SF1	UPF0719 INNER MEMBRANE PROTEIN YJFL	UPF0719 INNER MEMBRANE PROTEIN YJFL			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1415|UniProtKB=P25553	P25553	aldA	PTHR43353:SF15	SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL	LACTALDEHYDE DEHYDROGENASE-RELATED	aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491	oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	Gamma-aminobutyric acid synthesis#P04384>Succinic semialdehyde dehydrogenase#P04481
ECOLI|EnsemblGenome=b4153|UniProtKB=P0AC47	P0AC47	frdB	PTHR43551:SF2	FUMARATE REDUCTASE IRON-SULFUR SUBUNIT	FUMARATE REDUCTASE IRON-SULFUR SUBUNIT		energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;anaerobic respiration#GO:0009061;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;membrane#GO:0016020;respiratory chain complex#GO:0098803;catalytic complex#GO:1902494	dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0786|UniProtKB=P0AAC4	P0AAC4	ybhL	PTHR23291:SF128	BAX INHIBITOR-RELATED	INNER MEMBRANE PROTEIN YBHL	monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;transporter activity#GO:0005215	regulation of proteolysis#GO:0030162;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	ion channel#PC00133;transporter#PC00227	
ECOLI|EnsemblGenome=b2284|UniProtKB=P31979	P31979	nuoF	PTHR11780:SF12	NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1  NDUFV1	NADH-QUINONE OXIDOREDUCTASE SUBUNIT F	NADH dehydrogenase activity#GO:0003954;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491	cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271	oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3528|UniProtKB=P0A830	P0A830	dctA	PTHR42865:SF1	PROTON/GLUTAMATE-ASPARTATE SYMPORTER	AEROBIC C4-DICARBOXYLATE TRANSPORT PROTEIN	solute:proton symporter activity#GO:0015295;C4-dicarboxylate transmembrane transporter activity#GO:0015556;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;dicarboxylic acid transmembrane transporter activity#GO:0005310;active transmembrane transporter activity#GO:0022804;succinate transmembrane transporter activity#GO:0015141	establishment of localization#GO:0051234;acidic amino acid transport#GO:0015800;organic acid transport#GO:0015849;C4-dicarboxylate transport#GO:0015740;amino acid transport#GO:0006865;transport#GO:0006810;carboxylic acid transport#GO:0046942;dicarboxylic acid transport#GO:0006835;aspartate transmembrane transport#GO:0015810;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	primary active transporter#PC00068	
ECOLI|EnsemblGenome=b2127|UniProtKB=P33358	P33358	mlrA	PTHR30204:SF67	REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR	HTH-TYPE TRANSCRIPTIONAL REGULATOR MLRA-RELATED	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252		helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b2247|UniProtKB=P77215	P77215	rhmD	PTHR13794:SF58	ENOLASE SUPERFAMILY, MANDELATE RACEMASE	MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1				epimerase/racemase#PC00096	
ECOLI|EnsemblGenome=b1889|UniProtKB=P0AF06	P0AF06	motB	PTHR30329:SF18	STATOR ELEMENT OF FLAGELLAR MOTOR COMPLEX	MOTILITY PROTEIN B		bacterial-type flagellum-dependent swarming motility#GO:0071978;archaeal or bacterial-type flagellum-dependent cell motility#GO:0097588;cellular process#GO:0009987;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;bacterial-type flagellum-dependent cell motility#GO:0071973	plasma membrane#GO:0005886;cell projection#GO:0042995;organelle#GO:0043226;bacterial-type flagellum#GO:0009288;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;membraneless organelle#GO:0043228	structural protein#PC00211	
ECOLI|EnsemblGenome=b0838|UniProtKB=P0ACA7	P0ACA7	gstB	PTHR43900:SF101	GLUTATHIONE S-TRANSFERASE RHO	GLUTATHIONE S-TRANSFERASE GSTB	catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;glutathione transferase activity#GO:0004364;anion binding#GO:0043168		intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	transferase#PC00220	
ECOLI|EnsemblGenome=b4131|UniProtKB=P0A9H3	P0A9H3	cadA	PTHR43643:SF2	HISTIDINOL-PHOSPHATE AMINOTRANSFERASE 2	INDUCIBLE LYSINE DECARBOXYLASE				transaminase#PC00216;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1542|UniProtKB=P77260	P77260	ydfI	PTHR43362:SF4	MANNITOL DEHYDROGENASE DSF1-RELATED	MANNITOL DEHYDROGENASE	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616			metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0793|UniProtKB=P0AFQ2	P0AFQ2	ybhS	PTHR30294:SF29	MEMBRANE COMPONENT OF ABC TRANSPORTER YHHJ-RELATED	MULTIDRUG ABC TRANSPORTER PERMEASE YBHS-RELATED				primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0394|UniProtKB=P23917	P23917	mak	PTHR18964:SF174	ROK (REPRESSOR, ORF, KINASE) FAMILY	D-ALLOSE KINASE-RELATED	carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;hexokinase activity#GO:0004396			winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b3641|UniProtKB=P0C093	P0C093	slmA	PTHR30055:SF183	HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR	NUCLEOID OCCLUSION FACTOR SLMA	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110	biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355		Tet repressor-like transcription factor#PC00266	
ECOLI|EnsemblGenome=b0717|UniProtKB=P75749	P75749	ybgP	PTHR30251:SF5	PILUS ASSEMBLY CHAPERONE	FIMBRIAL CHAPARONE PROTEIN		protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238	periplasmic space#GO:0042597;extracellular region#GO:0005576;cell envelope#GO:0030313;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165	chaperone#PC00072	
ECOLI|EnsemblGenome=b2886|UniProtKB=Q46819	Q46819	ygfS	PTHR42859:SF17	OXIDOREDUCTASE	ELECTRON TRANSPORT PROTEIN HYDN-RELATED				oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3779|UniProtKB=P25552	P25552	gppA	PTHR30005:SF16	EXOPOLYPHOSPHATASE	GUANOSINE-5'-TRIPHOSPHATE,3'-DIPHOSPHATE PYROPHOSPHATASE	catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787	primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound metabolic process#GO:0006139		metabolite interconversion enzyme#PC00262;phosphatase#PC00181	
ECOLI|EnsemblGenome=b1747|UniProtKB=P0AE37	P0AE37	astA	PTHR30420:SF1	N-SUCCINYLARGININE DIHYDROLASE	ARGININE N-SUCCINYLTRANSFERASE	catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;arginine metabolic process#GO:0006525;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752		metabolite interconversion enzyme#PC00262;hydrolase#PC00121	
ECOLI|EnsemblGenome=b2129|UniProtKB=P33360	P33360	yehX	PTHR43117:SF5	OSMOPROTECTANT IMPORT ATP-BINDING PROTEIN OSMV	GLYCINE BETAINE UPTAKE SYSTEM ATP-BINDING PROTEIN YEHX	quaternary ammonium group transmembrane transporter activity#GO:0015651;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b3524|UniProtKB=P37645	P37645	yhjG	PTHR30441:SF9	DUF748 DOMAIN-CONTAINING PROTEIN	ASMA FAMILY PROTEIN YHJG		regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of establishment of protein localization#GO:0070201;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;biological regulation#GO:0065007	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b0128|UniProtKB=P0AFN6	P0AFN6	yadH	PTHR43332:SF2	INNER MEMBRANE TRANSPORT PERMEASE YADH-RELATED	INNER MEMBRANE TRANSPORT PERMEASE YADH			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b3567|UniProtKB=P37388	P37388	xylG	PTHR43790:SF1	CARBOHYDRATE TRANSPORT ATP-BINDING PROTEIN MG119-RELATED	XYLOSE IMPORT ATP-BINDING PROTEIN XYLG	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b3588|UniProtKB=P37685	P37685	aldB	PTHR43111:SF1	ALDEHYDE DEHYDROGENASE B-RELATED	ALDEHYDE DEHYDROGENASE B-RELATED	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824			dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402
ECOLI|EnsemblGenome=b3576|UniProtKB=P37673	P37673	yiaL	PTHR34986:SF1	EVOLVED BETA-GALACTOSIDASE SUBUNIT BETA	PROTEIN YIAL			cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	galactosidase#PC00104;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b4117|UniProtKB=P28629	P28629	adiA	PTHR45229:SF5	CONSTITUTIVE ORNITHINE DECARBOXYLASE	BIODEGRADATIVE ARGININE DECARBOXYLASE	ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363	oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	decarboxylase#PC00089;metabolite interconversion enzyme#PC00262;lyase#PC00144	
ECOLI|EnsemblGenome=b1631|UniProtKB=P77285	P77285	rsxG	PTHR36118:SF1	ION-TRANSLOCATING OXIDOREDUCTASE COMPLEX SUBUNIT G	ION-TRANSLOCATING OXIDOREDUCTASE COMPLEX SUBUNIT G			cell periphery#GO:0071944;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165		
ECOLI|Gene_OrderedLocusName=JW1571|UniProtKB=P76168	P76168	intQ	PTHR30349:SF96	PHAGE INTEGRASE-RELATED	PROPHAGE INTEGRASE INTR-RELATED	catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097	metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;chromosome segregation#GO:0007059;macromolecule metabolic process#GO:0043170;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle process#GO:0022402;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139		viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b2520|UniProtKB=P76578	P76578	yfhM	PTHR40094:SF1	ALPHA-2-MACROGLOBULIN HOMOLOG	ALPHA-2-MACROGLOBULIN	enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678				
ECOLI|EnsemblGenome=b3136|UniProtKB=P42907	P42907	agaS	PTHR32502:SF3	N-ACETYLGALACTOSAMINE PERMEASE II COMPONENT-RELATED	D-GALACTOSAMINE-6-PHOSPHATE DEAMINASE AGAS-RELATED		carbohydrate transport#GO:0008643;transport#GO:0006810;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;transmembrane transport#GO:0055085;cellular process#GO:0009987;import across plasma membrane#GO:0098739;carbohydrate transmembrane transport#GO:0034219	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b1662|UniProtKB=P0AFU8	P0AFU8	ribC	PTHR21098:SF0	RIBOFLAVIN SYNTHASE ALPHA CHAIN	RIBOFLAVIN SYNTHASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765	biosynthetic process#GO:0009058;flavin-containing compound metabolic process#GO:0042726;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152		transferase#PC00220	Flavin biosynthesis#P02741>Riboflavin synthase#P02940
ECOLI|EnsemblGenome=b0275|UniProtKB=P0CF09	P0CF09	insA3	PTHR47923:SF1	INSERTION ELEMENT IS1 1 PROTEIN INSA-RELATED	INSERTION ELEMENT IS1 1 PROTEIN INSA-RELATED		macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238			
ECOLI|EnsemblGenome=b2289|UniProtKB=P36771	P36771	lrhA	PTHR30579:SF7	TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR LRHA-RELATED	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889		gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b1324|UniProtKB=P0A862	P0A862	tpx	PTHR43110:SF1	THIOL PEROXIDASE	THIOL PEROXIDASE	catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491	cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;cellular response to oxidative stress#GO:0034599;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950		metabolite interconversion enzyme#PC00262;peroxidase#PC00180;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0546|UniProtKB=P77634	P77634	ybcM	PTHR47894:SF4	HTH-TYPE TRANSCRIPTIONAL REGULATOR GADX	HTH-TYPE TRANSCRIPTIONAL REGULATOR GADX	double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837			DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b2255|UniProtKB=P77398	P77398	arnA	PTHR43245:SF13	BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA	UDP-D-APIOSE_UDP-D-XYLOSE SYNTHASE 1-RELATED					
ECOLI|EnsemblGenome=b2665|UniProtKB=P0ADE6	P0ADE6	kbp	PTHR34700:SF8	POTASSIUM BINDING PROTEIN KBP	POTASSIUM BINDING PROTEIN KBP	cation binding#GO:0043169;metal ion binding#GO:0046872;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167	response to stimulus#GO:0050896;response to chemical#GO:0042221;response to metal ion#GO:0010038			
ECOLI|EnsemblGenome=b2619|UniProtKB=P0AGL5	P0AGL5	ratA	PTHR12901:SF17	SPERM PROTEIN HOMOLOG	RIBOSOME ASSOCIATION TOXIN RATA					
ECOLI|EnsemblGenome=b4278|UniProtKB=P03835	P03835	insG	PTHR37529:SF1	TRANSPOSASE INSG FOR INSERTION SEQUENCE ELEMENT IS4-RELATED	TRANSPOSASE INSG FOR INSERTION SEQUENCE ELEMENT IS4-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b0812|UniProtKB=P0ABT2	P0ABT2	dps	PTHR42932:SF3	GENERAL STRESS PROTEIN 20U	DNA PROTECTION DURING STARVATION PROTEIN	nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677	negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA replication#GO:0006275;regulation of biological process#GO:0050789;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of DNA-templated DNA replication#GO:2000104;negative regulation of cellular process#GO:0048523;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;regulation of DNA-templated DNA replication initiation#GO:0030174;regulation of nucleobase-containing compound metabolic process#GO:0019219	intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993;organelle#GO:0043226;replication fork#GO:0005657;replisome#GO:0030894;chromosome#GO:0005694		
ECOLI|EnsemblGenome=b1587|UniProtKB=P77374	P77374	ynfE	PTHR43742:SF7	TRIMETHYLAMINE-N-OXIDE REDUCTASE	DIMETHYL SULFOXIDE REDUCTASE CHAIN YNFE-RELATED	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;metabolic process#GO:0008152;anaerobic respiration#GO:0009061;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980	cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;extracellular region#GO:0005576;periplasmic space#GO:0042597	reductase#PC00198	
ECOLI|EnsemblGenome=b1254|UniProtKB=P0A710	P0A710	yciB	PTHR36917:SF1	INTRACELLULAR SEPTATION PROTEIN A-RELATED	INNER MEMBRANE-SPANNING PROTEIN YCIB			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b3809|UniProtKB=P0A6K1	P0A6K1	dapF	PTHR31689:SF10	DIAMINOPIMELATE EPIMERASE, CHLOROPLASTIC	DIAMINOPIMELATE EPIMERASE	isomerase activity#GO:0016853;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854	carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;aspartate family amino acid biosynthetic process#GO:0009067;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;L-lysine biosynthetic process#GO:0009085;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;proteinogenic amino acid biosynthetic process#GO:0170038	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165		Lysine biosynthesis#P02751>Diaminopimelate epimerase#P03010
ECOLI|EnsemblGenome=b4125|UniProtKB=P0AEC8	P0AEC8	dcuS	PTHR43547:SF10	TWO-COMPONENT HISTIDINE KINASE	SENSOR HISTIDINE KINASE DCUS	protein histidine kinase activity#GO:0004673;catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;catalytic activity#GO:0003824;phosphorelay sensor kinase activity#GO:0000155;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672			histidine kinase receptor of two-component system#PC00265	
ECOLI|EnsemblGenome=b1046|UniProtKB=P75919	P75919	clsC	PTHR21248:SF12	CARDIOLIPIN SYNTHASE	CARDIOLIPIN SYNTHASE C	phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824	organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphatidylglycerol metabolic process#GO:0046471;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;phosphatidylglycerol biosynthetic process#GO:0006655;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058		transferase#PC00220	
ECOLI|EnsemblGenome=b4234|UniProtKB=P0A8X0	P0A8X0	darP	PTHR38101:SF1	UPF0307 PROTEIN YJGA	DUAL-ACTION RIBOSOMAL MATURATION PROTEIN DARP					
ECOLI|EnsemblGenome=b4557|UniProtKB=P0A8C8	P0A8C8	yidD	PTHR33383:SF2	MEMBRANE PROTEIN INSERTION EFFICIENCY FACTOR-RELATED	MEMBRANE PROTEIN INSERTION EFFICIENCY FACTOR-RELATED	protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977;molecular carrier activity#GO:0140104	establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;localization within membrane#GO:0051668;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;cellular component organization#GO:0016043;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1962|UniProtKB=P46144	P46144	yedJ	PTHR33594:SF1	SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G03035)-RELATED	HD_PDEASE DOMAIN-CONTAINING PROTEIN				hydrolase#PC00121;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2113|UniProtKB=P0AF08	P0AF08	mrp	PTHR42961:SF3	IRON-SULFUR PROTEIN NUBPL	IRON-SULFUR CLUSTER CARRIER PROTEIN	binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536	cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;iron-sulfur cluster assembly#GO:0016226;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b3460|UniProtKB=P0AD96	P0AD96	livJ	PTHR47151:SF1	LEU/ILE/VAL-BINDING ABC TRANSPORTER SUBUNIT	LEU_ILE_VAL-BINDING PROTEIN		amino acid transport#GO:0006865;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;branched-chain amino acid transport#GO:0015803;localization#GO:0051179;establishment of localization#GO:0051234;neutral amino acid transport#GO:0015804;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;L-leucine transport#GO:0015820	periplasmic space#GO:0042597;extracellular region#GO:0005576;cell envelope#GO:0030313;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227	
ECOLI|EnsemblGenome=b1344|UniProtKB=P76055	P76055	ttcA	PTHR43686:SF2	SULFURTRANSFERASE-RELATED	TRNA-CYTIDINE(32) 2-SULFURTRANSFERASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783	primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;tRNA thio-modification#GO:0034227;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	transferase#PC00220;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3106|UniProtKB=P42624	P42624	yhaK	PTHR43212:SF2	QUERCETIN 2,3-DIOXYGENASE	PIRIN-LIKE PROTEIN YHAK	catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491			oxidoreductase#PC00176;oxygenase#PC00177	
ECOLI|EnsemblGenome=b3884|UniProtKB=P32144	P32144	csqR	PTHR30363:SF19	HTH-TYPE TRANSCRIPTIONAL REGULATOR SRLR-RELATED	HTH-TYPE TRANSCRIPTIONAL REPRESSOR CSQR	nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468		helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b4389|UniProtKB=P24554	P24554	radA	PTHR32472:SF10	DNA REPAIR PROTEIN RADA	DNA REPAIR PROTEIN RADA-LIKE PROTEIN		macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA repair#GO:0006281;recombinational repair#GO:0000725;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;cellular response to stimulus#GO:0051716		DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b0219|UniProtKB=Q47679	Q47679	yafV	PTHR47799:SF1	OMEGA-AMIDASE YAFV	OMEGA-AMIDASE YAFV	hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824				
ECOLI|EnsemblGenome=b0090|UniProtKB=P17443	P17443	murG	PTHR21015:SF29	UDP-N-ACETYLGLUCOSAMINE--N-ACETYLMURAMYL-(PENTAPEPTIDE) PYROPHOSPHORYL-UNDECAPRENOL N-ACETYLGLUCOSAMINE TRANSFERASE 1	UDP-N-ACETYLGLUCOSAMINE--N-ACETYLMURAMYL-(PENTAPEPTIDE) PYROPHOSPHORYL-UNDECAPRENOL N-ACETYLGLUCOSAMINE TRANSFERASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;acetylglucosaminyltransferase activity#GO:0008375			metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111	Peptidoglycan biosynthesis#P02763>N-Acetylglucosaminyl transferase#P03090
ECOLI|EnsemblGenome=b0482|UniProtKB=P77301	P77301	ybaP	PTHR40590:SF1	CYTOPLASMIC PROTEIN-RELATED	GUMN PROTEIN					
ECOLI|EnsemblGenome=b3003|UniProtKB=P0AG84	P0AG84	yghA	PTHR42760:SF132	SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER	SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN	catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0962|UniProtKB=P15038	P15038	helD	PTHR11070:SF63	UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER	DNA HELICASE IV	helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657	primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;recombinational repair#GO:0000725;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA recombination#GO:0006310;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b2128|UniProtKB=P33359	P33359	yehW	PTHR30177:SF32	GLYCINE BETAINE/L-PROLINE TRANSPORT SYSTEM PERMEASE PROTEIN PROW	GLYCINE BETAINE UPTAKE SYSTEM PERMEASE PROTEIN YEHW					
ECOLI|EnsemblGenome=b2180|UniProtKB=P33916	P33916	yejF	PTHR24220:SF607	IMPORT ATP-BINDING PROTEIN	NICKEL IMPORT ATP-BINDING PROTEIN NIKD-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	transport#GO:0006810;oligopeptide transport#GO:0006857;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;oligopeptide transmembrane transport#GO:0035672;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b0127|UniProtKB=P36879	P36879	yadG	PTHR42711:SF15	ABC TRANSPORTER ATP-BINDING PROTEIN	ATP-BINDING COMPONENT OF ABC TRANSPORTER-RELATED		response to abiotic stimulus#GO:0009628;response to ionizing radiation#GO:0010212;response to radiation#GO:0009314;response to stimulus#GO:0050896	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227	
ECOLI|EnsemblGenome=b3915|UniProtKB=P69380	P69380	fieF	PTHR43840:SF15	MITOCHONDRIAL METAL TRANSPORTER 1-RELATED	MITOCHONDRIAL METAL TRANSPORTER 1-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324		cellular anatomical structure#GO:0110165;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b2120|UniProtKB=P33349	P33349	yehM	PTHR30634:SF7	OUTER MEMBRANE LOLAB LIPOPROTEIN INSERTION APPARATUS	VWA DOMAIN-CONTAINING PROTEIN				transporter#PC00227	
ECOLI|EnsemblGenome=b0007|UniProtKB=P30143	P30143	yaaJ	PTHR30330:SF1	AGSS FAMILY TRANSPORTER, SODIUM-ALANINE	SODIUM_ALANINE SYMPORTER YAAJ-RELATED			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b0578|UniProtKB=P38489	P38489	nfsB	PTHR23026:SF125	NADPH NITROREDUCTASE	OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824		cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;reductase#PC00198	
ECOLI|EnsemblGenome=b0242|UniProtKB=P0A7B5	P0A7B5	proB	PTHR43654:SF4	GLUTAMATE 5-KINASE	GLUTAMATE 5-KINASE	transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;catalytic activity#GO:0003824	cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	amino acid kinase#PC00045;metabolite interconversion enzyme#PC00262;kinase#PC00137	Proline biosynthesis#P02768>Glutamyl kinase#P03114
ECOLI|EnsemblGenome=b4016|UniProtKB=P11071	P11071	aceK	PTHR39559:SF1	ISOCITRATE DEHYDROGENASE KINASE_PHOSPHATASE	ISOCITRATE DEHYDROGENASE KINASE_PHOSPHATASE	kinase activity#GO:0016301;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatase activity#GO:0016791;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;hydrolase activity#GO:0016787	small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;alcohol metabolic process#GO:0006066;cellular process#GO:0009987			
ECOLI|EnsemblGenome=b3424|UniProtKB=P09391	P09391	glpG	PTHR43066:SF26	RHOMBOID-RELATED PROTEIN	RHOMBOID PROTEASE GLPG	catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236			protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190	
ECOLI|EnsemblGenome=b4371|UniProtKB=P39406	P39406	rsmC	PTHR47816:SF4	RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE C	RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE C	catalytic activity, acting on a rRNA#GO:0140102;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;rRNA (guanine) methyltransferase activity#GO:0016435;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740	rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;rRNA methylation#GO:0031167;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;rRNA base methylation#GO:0070475;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;methylation#GO:0032259;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA modification#GO:0000154;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774		RNA processing factor#PC00147;RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b4150|UniProtKB=P00811	P00811	ampC	PTHR46825:SF9	D-ALANYL-D-ALANINE-CARBOXYPEPTIDASE/ENDOPEPTIDASE AMPH	BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN				hydrolase#PC00121;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1271|UniProtKB=P31808	P31808	yciK	PTHR42901:SF1	ALCOHOL DEHYDROGENASE	SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN				dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1397|UniProtKB=P0C7L2	P0C7L2	paaJ	PTHR43853:SF2	3-KETOACYL-COA THIOLASE, PEROXISOMAL	3-OXOADIPYL-COA_3-OXO-5,6-DEHYDROSUBERYL-COA THIOLASE	acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824	monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258		acetyltransferase#PC00038	
ECOLI|EnsemblGenome=b0491|UniProtKB=P77307	P77307	fetB	PTHR30028:SF0	UPF0014 INNER MEMBRANE PROTEIN YBBM-RELATED	IRON EXPORT PERMEASE PROTEIN FETB-RELATED			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0072|UniProtKB=P0A6A6	P0A6A6	leuC	PTHR43822:SF9	HOMOACONITASE, MITOCHONDRIAL-RELATED	3-ISOPROPYLMALATE DEHYDRATASE					Leucine biosynthesis#P02749>Isopropylmalate isomerase#P03002
ECOLI|EnsemblGenome=b0117|UniProtKB=P36682	P36682	yacH	PTHR40269:SF1	OUTER MEMBRANE PROTEIN-RELATED	DUF3300 DOMAIN-CONTAINING PROTEIN					
ECOLI|Gene_OrderedLocusName=JW5037|UniProtKB=P77601	P77601	ykgA	PTHR47504:SF3	RIGHT ORIGIN-BINDING PROTEIN	HTH-TYPE TRANSCRIPTIONAL REGULATOR YKGA-RELATED	nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;protein binding#GO:0005515;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119	
ECOLI|EnsemblGenome=b3683|UniProtKB=P31452	P31452	glvC	PTHR30009:SF12	CYTOCHROME C-TYPE SYNTHESIS PROTEIN AND PTS TRANSMEMBRANE COMPONENT	PHOSPHOTRANSFERASE IIC COMPONENT GLVC	phosphotransferase activity, alcohol group as acceptor#GO:0016773;carbohydrate transmembrane transporter activity#GO:0015144;protein-phosphocysteine-sugar phosphotransferase activity#GO:0090563;active transmembrane transporter activity#GO:0022804;transferase activity#GO:0016740;catalytic activity#GO:0003824;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transferase activity, transferring phosphorus-containing groups#GO:0016772	phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;localization#GO:0051179;import into cell#GO:0098657;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;carbohydrate transport#GO:0008643;transport#GO:0006810;import across plasma membrane#GO:0098739;carbohydrate transmembrane transport#GO:0034219;cellular process#GO:0009987	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b3869|UniProtKB=P0AFB5	P0AFB5	glnL	PTHR43065:SF16	SENSOR HISTIDINE KINASE	SENSORY HISTIDINE KINASE_PHOSPHATASE NTRB				histidine kinase receptor of two-component system#PC00265	
ECOLI|EnsemblGenome=b3025|UniProtKB=P52076	P52076	qseB	PTHR48111:SF35	REGULATOR OF RPOS	TRANSCRIPTIONAL REGULATORY PROTEIN QSEB	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;molecular transducer activity#GO:0060089;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789	cytosol#GO:0005829;protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b1386|UniProtKB=P46883	P46883	tynA	PTHR10638:SF41	COPPER AMINE OXIDASE	AMINE OXIDASE	oxidoreductase activity#GO:0016491;copper ion binding#GO:0005507;catalytic activity#GO:0003824;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914	metabolic process#GO:0008152;amine metabolic process#GO:0009308;cellular process#GO:0009987		oxidase#PC00175;oxidoreductase#PC00176	Phenylethylamine degradation#P02766>Phenylethylamine oxidase#P03103
ECOLI|EnsemblGenome=b1712|UniProtKB=P0A6X7	P0A6X7	ihfA	PTHR33175:SF2	DNA-BINDING PROTEIN HU	INTEGRATION HOST FACTOR SUBUNIT ALPHA	DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110	positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252	organelle#GO:0043226;protein-DNA complex#GO:0032993;nucleoid#GO:0009295;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;bacterial nucleoid#GO:0043590;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b4279|UniProtKB=P39352	P39352	nanX	PTHR23508:SF2	CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG	SIALIC ACID TRANSPORTER NANX	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b1893|UniProtKB=P0CF28	P0CF28	insB5	PTHR33293:SF1	INSERTION ELEMENT IS1 1 PROTEIN INSB-RELATED	INSERTION ELEMENT IS1 1 PROTEIN INSB-RELATED					
ECOLI|EnsemblGenome=b1109|UniProtKB=P00393	P00393	ndh	PTHR43706:SF9	NADH DEHYDROGENASE	TYPE II NADH:QUINONE OXIDOREDUCTASE	oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324;oxidoreductase activity, acting on NAD(P)H#GO:0016651;NADH dehydrogenase activity#GO:0003954			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3589|UniProtKB=P37686	P37686	yiaY	PTHR11496:SF83	ALCOHOL DEHYDROGENASE	HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL	catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614		membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739	dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b2771|UniProtKB=Q46909	Q46909	ygcS	PTHR23511:SF34	SYNAPTIC VESICLE GLYCOPROTEIN 2	SYNAPTIC VESICLE GLYCOPROTEIN 2B ISOFORM X1			cellular anatomical structure#GO:0110165;membrane#GO:0016020		
ECOLI|EnsemblGenome=b0629|UniProtKB=P30979	P30979	ybeF	PTHR30118:SF10	HTH-TYPE TRANSCRIPTIONAL REGULATOR LEUO-RELATED	LYSR FAMILY TRANSCRIPTIONAL REGULATOR	sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription activator activity#GO:0001216;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789	protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991	helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b1627|UniProtKB=P0A766	P0A766	rsxA	PTHR30335:SF0	INTEGRAL MEMBRANE PROTEIN OF SOXR-REDUCING COMPLEX	ION-TRANSLOCATING OXIDOREDUCTASE COMPLEX SUBUNIT A			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1693|UniProtKB=P05194	P05194	aroD	PTHR43699:SF1	3-DEHYDROQUINATE DEHYDRATASE	3-DEHYDROQUINATE DEHYDRATASE	hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824	monocarboxylic acid biosynthetic process#GO:0072330;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;phenol-containing compound biosynthetic process#GO:0046189;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;phenol-containing compound metabolic process#GO:0018958	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	dehydratase#PC00091;lyase#PC00144	Chorismate biosynthesis#P02734>3-Dehydroquinate dehydratase#P02869;Chorismate biosynthesis#P02734>Shikimate dehydrogenase#P02873
ECOLI|EnsemblGenome=b3357|UniProtKB=P0ACJ8	P0ACJ8	crp	PTHR24567:SF74	CRP FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN	DNA-BINDING TRANSCRIPTIONAL DUAL REGULATOR CRP	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110		cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b4316|UniProtKB=P31697	P31697	fimC	PTHR30251:SF11	PILUS ASSEMBLY CHAPERONE	CHAPERONE PROTEIN FIMC-RELATED		protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152	periplasmic space#GO:0042597;extracellular region#GO:0005576;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313	chaperone#PC00072	
ECOLI|EnsemblGenome=b4464|UniProtKB=Q46817	Q46817	ghxQ	PTHR43337:SF4	XANTHINE/URACIL PERMEASE C887.17-RELATED	GUANINE_HYPOXANTHINE PERMEASE GHXQ	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;nucleobase transmembrane transporter activity#GO:0015205		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b1250|UniProtKB=P31069	P31069	kch	PTHR43833:SF9	POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED	VOLTAGE-GATED POTASSIUM CHANNEL KCH	passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324	cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227;ion channel#PC00133	
ECOLI|EnsemblGenome=b1108|UniProtKB=P0A8E1	P0A8E1	ycfP	PTHR35602:SF2	ESTERASE YQIA-RELATED	UPF0227 PROTEIN YCFP	hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097	
ECOLI|EnsemblGenome=b1110|UniProtKB=P0AB35	P0AB35	ycfJ	PTHR35603:SF2	FAMILY NOT NAMED	GLYCINE ZIPPER 2TM DOMAIN-CONTAINING PROTEIN					
ECOLI|EnsemblGenome=b3702|UniProtKB=P03004	P03004	dnaA	PTHR30050:SF2	CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA	CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA	DNA replication origin binding#GO:0003688;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565	DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b0337|UniProtKB=P25524	P25524	codA	PTHR32027:SF0	CYTOSINE DEAMINASE	CYTOSINE DEAMINASE	hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;catalytic activity#GO:0003824	metabolic process#GO:0008152;pyrimidine nucleobase metabolic process#GO:0006206;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;pyrimidine nucleobase catabolic process#GO:0006208;primary metabolic process#GO:0044238;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;nucleobase catabolic process#GO:0046113		deaminase#PC00088	Salvage pyrimidine ribonucleotides#P02775>Cytosine deaminase#P03155
ECOLI|EnsemblGenome=b1637|UniProtKB=P0AGJ9	P0AGJ9	tyrS	PTHR11766:SF2	TYROSYL-TRNA SYNTHETASE	TYROSINE--TRNA LIGASE	catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874	metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;amino acid activation#GO:0043038;tRNA aminoacylation#GO:0043039;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520		translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047	
ECOLI|EnsemblGenome=b1047|UniProtKB=P75920	P75920	mdoC	PTHR36927:SF3	BLR4337 PROTEIN	GLUCANS BIOSYNTHESIS PROTEIN C	acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740	polysaccharide metabolic process#GO:0005976;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glucan biosynthetic process#GO:0009250;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;polysaccharide biosynthetic process#GO:0000271			
ECOLI|EnsemblGenome=b0401|UniProtKB=P0AD99	P0AD99	brnQ	PTHR30588:SF0	BRANCHED-CHAIN AMINO ACID TRANSPORT SYSTEM 2 CARRIER PROTEIN	BRANCHED-CHAIN AMINO ACID PERMEASE BRNQ	L-amino acid transmembrane transporter activity#GO:0015179;branched-chain amino acid transmembrane transporter activity#GO:0015658;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215	L-leucine transport#GO:0015820;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;localization#GO:0051179;neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234;branched-chain amino acid transport#GO:0015803;organic acid transport#GO:0015849;transport#GO:0006810;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b0208|UniProtKB=P30864	P30864	yafC	PTHR30126:SF102	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR PTXR	sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090		helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b4382|UniProtKB=P07650	P07650	deoA	PTHR10515:SF0	THYMIDINE PHOSPHORYLASE	THYMIDINE PHOSPHORYLASE	glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740		cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	glycosyltransferase#PC00111	Salvage pyrimidine deoxyribonucleotides#P02774>Uracil phosphorylase#P03145;Pyrimidine Metabolism#P02771>Nucleoside Phosphorylase#P03126;Salvage pyrimidine deoxyribonucleotides#P02774>Thymidine phosphorylase#P03148
ECOLI|EnsemblGenome=b1069|UniProtKB=P0AF16	P0AF16	murJ	PTHR47019:SF1	LIPID II FLIPPASE MURJ	LIPID II FLIPPASE MURJ	carbohydrate derivative transmembrane transporter activity#GO:1901505;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	peptidoglycan biosynthetic process#GO:0009252;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;aminoglycan metabolic process#GO:0006022;lipid localization#GO:0010876;cell wall organization or biogenesis#GO:0071554;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;carbohydrate derivative biosynthetic process#GO:1901137;glycosaminoglycan biosynthetic process#GO:0006024;cellular component organization or biogenesis#GO:0071840;peptidoglycan-based cell wall biogenesis#GO:0009273;peptidoglycan metabolic process#GO:0000270;metabolic process#GO:0008152;lipid translocation#GO:0034204;carbohydrate derivative transport#GO:1901264;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan metabolic process#GO:0030203;cell wall macromolecule metabolic process#GO:0044036;cell wall biogenesis#GO:0042546;localization#GO:0051179;membrane organization#GO:0061024;biological regulation#GO:0065007;biosynthetic process#GO:0009058;lipid transport#GO:0006869;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;cell wall macromolecule biosynthetic process#GO:0044038;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;transport#GO:0006810	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b4086|UniProtKB=P32720	P32720	alsC	PTHR32196:SF21	ABC TRANSPORTER PERMEASE PROTEIN YPHD-RELATED-RELATED	ABC TRANSPORTER PERMEASE PROTEIN YPHD-RELATED			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b4468|UniProtKB=P52073	P52073	glcE	PTHR11748:SF103	D-LACTATE DEHYDROGENASE	GLYCOLATE OXIDASE SUBUNIT GLCE				dehydrogenase#PC00092;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2192|UniProtKB=P0CE55	P0CE55	insH8	PTHR35604:SF2	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097	DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b1014|UniProtKB=P09546	P09546	putA	PTHR42862:SF2	DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 1, ISOFORM A-RELATED	BIFUNCTIONAL PROTEIN PUTA	oxidoreductase activity#GO:0016491;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281	plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898	dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3514|UniProtKB=P37637	P37637	mdtF	PTHR32063:SF13	SWARMING MOTILITY PROTEIN SWRC-RELATED	MULTIDRUG EFFLUX PUMP SUBUNIT ACRB-RELATED					
ECOLI|EnsemblGenome=b3720|UniProtKB=P26218	P26218	bglH	PTHR38762:SF1	CRYPTIC OUTER MEMBRANE PORIN BGLH-RELATED	CRYPTIC OUTER MEMBRANE PORIN BGLH-RELATED	passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;carbohydrate transmembrane transporter activity#GO:0015144;channel activity#GO:0015267	establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;carbohydrate transport#GO:0008643;macromolecule localization#GO:0033036	outer membrane#GO:0019867;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;cell outer membrane#GO:0009279;membrane#GO:0016020;cell envelope#GO:0030313;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0385|UniProtKB=P0AAP1	P0AAP1	dgcC	PTHR45138:SF29	REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM	DIGUANYLATE CYCLASE DGCC-RELATED	transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824	regulation of locomotion#GO:0040012;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;negative regulation of locomotion#GO:0040013;regulation of cellular process#GO:0050794;cellular process#GO:0009987;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell motility#GO:2000145;cell-substrate adhesion#GO:0031589;cell adhesion#GO:0007155;negative regulation of cellular process#GO:0048523;single-species biofilm formation#GO:0044010	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b0022|UniProtKB=P0CF07	P0CF07	insA1	PTHR47923:SF1	INSERTION ELEMENT IS1 1 PROTEIN INSA-RELATED	INSERTION ELEMENT IS1 1 PROTEIN INSA-RELATED		nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA recombination#GO:0006310			
ECOLI|EnsemblGenome=b2310|UniProtKB=P09551	P09551	argT	PTHR35936:SF23	MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE F	LYSINE_ARGININE_ORNITHINE-BINDING PERIPLASMIC PROTEIN	amino acid binding#GO:0016597;binding#GO:0005488		cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;extracellular region#GO:0005576;periplasmic space#GO:0042597		
ECOLI|EnsemblGenome=b2202|UniProtKB=P0ABL5	P0ABL5	napC	PTHR30333:SF1	CYTOCHROME C-TYPE PROTEIN	CYTOCHROME C-TYPE PROTEIN NAPC		respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;anaerobic electron transport chain#GO:0019645;anaerobic respiration#GO:0009061;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333		transporter#PC00227;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b3201|UniProtKB=P0A9V1	P0A9V1	lptB	PTHR45772:SF10	CONSERVED COMPONENT OF ABC TRANSPORTER FOR NATURAL AMINO ACIDS-RELATED	LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b3429|UniProtKB=P0A6U8	P0A6U8	glgA	PTHR45825:SF23	GRANULE-BOUND STARCH SYNTHASE 1, CHLOROPLASTIC/AMYLOPLASTIC	GLYCOGEN SYNTHASE	glycosyltransferase activity#GO:0016757;glucosyltransferase activity#GO:0046527;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758	carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042;glycogen metabolic process#GO:0005977;glucan biosynthetic process#GO:0009250;polysaccharide biosynthetic process#GO:0000271;energy reserve metabolic process#GO:0006112;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;glycogen biosynthetic process#GO:0005978;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b3352|UniProtKB=P63389	P63389	yheS	PTHR19211:SF138	ATP-BINDING TRANSPORT PROTEIN-RELATED	ATP-BINDING PROTEIN YHES-RELATED	nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168			translation elongation factor#PC00222	
ECOLI|EnsemblGenome=b3904|UniProtKB=P32171	P32171	rhaB	PTHR10196:SF93	SUGAR KINASE	L-RHAMNULOKINASE	phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824	monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052;cellular process#GO:0009987;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	carbohydrate kinase#PC00065;kinase#PC00137	
ECOLI|EnsemblGenome=b0633|UniProtKB=P10100	P10100	rlpA	PTHR34183:SF9	ENDOLYTIC PEPTIDOGLYCAN TRANSGLYCOSYLASE RLPA	ENDOLYTIC PEPTIDOGLYCAN TRANSGLYCOSYLASE RLPA			membrane#GO:0016020;cell outer membrane#GO:0009279;external encapsulating structure#GO:0030312;outer membrane#GO:0019867;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313		
ECOLI|EnsemblGenome=b2552|UniProtKB=P24232	P24232	hmp	PTHR43396:SF3	FLAVOHEMOPROTEIN	FLAVOHEMOPROTEIN	nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488	detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;response to nitrogen compound#GO:1901698;cellular response to chemical stress#GO:0062197;cellular response to stress#GO:0033554;cellular detoxification#GO:1990748;cellular response to chemical stimulus#GO:0070887	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b3401|UniProtKB=P0A6Y5	P0A6Y5	hslO	PTHR30111:SF1	33 KDA CHAPERONIN	33 KDA CHAPERONIN		metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein refolding#GO:0042026;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	chaperone#PC00072	
ECOLI|EnsemblGenome=b0832|UniProtKB=P75799	P75799	gsiD	PTHR43386:SF3	OLIGOPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN APPC	GLUTATHIONE TRANSPORT SYSTEM PERMEASE PROTEIN GSID	oligopeptide transmembrane transporter activity#GO:0035673;dipeptide transmembrane transporter activity#GO:0071916;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b0993|UniProtKB=P39453	P39453	torS	PTHR43719:SF71	TWO-COMPONENT HISTIDINE KINASE	SENSOR PROTEIN TORS	phosphoric ester hydrolase activity#GO:0042578;kinase activity#GO:0016301;transferase activity#GO:0016740;phosphorelay sensor kinase activity#GO:0000155;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;catalytic activity, acting on a protein#GO:0140096;protein histidine kinase activity#GO:0004673;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787	response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;phosphorelay signal transduction system#GO:0000160;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	histidine kinase receptor of two-component system#PC00265;transmembrane signal receptor#PC00197	
ECOLI|EnsemblGenome=b3449|UniProtKB=P10908	P10908	ugpQ	PTHR46211:SF15	GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE	GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE, CYTOPLASMIC	hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578			phosphodiesterase#PC00185	
ECOLI|EnsemblGenome=b0446|UniProtKB=P46891	P46891	cof	PTHR47267:SF2	FAMILY NOT NAMED	HMP-PP PHOSPHATASE	small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;magnesium ion binding#GO:0000287;cation binding#GO:0043169;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578				
ECOLI|EnsemblGenome=b2137|UniProtKB=P33368	P33368	yohF	PTHR43669:SF14	5-KETO-D-GLUCONATE 5-REDUCTASE	5-KETO-D-GLUCONATE 5-REDUCTASE	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3804|UniProtKB=P09126	P09126	hemD	PTHR38042:SF1	UROPORPHYRINOGEN-III SYNTHASE, CHLOROPLASTIC	UROPORPHYRINOGEN-III SYNTHASE	catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835				
ECOLI|EnsemblGenome=b2587|UniProtKB=P0AEX3	P0AEX3	kgtP	PTHR43528:SF9	ALPHA-KETOGLUTARATE PERMEASE	ALPHA-KETOGLUTARATE PERMEASE	monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b0347|UniProtKB=P77397	P77397	mhpA	PTHR43476:SF3	3-(3-HYDROXY-PHENYL)PROPIONATE/3-HYDROXYCINNAMIC ACID HYDROXYLASE	3-(3-HYDROXY-PHENYL)PROPIONATE_3-HYDROXYCINNAMIC ACID HYDROXYLASE	monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;alcohol metabolic process#GO:0006066;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752		oxidoreductase#PC00176;hydroxylase#PC00122	
ECOLI|EnsemblGenome=b1603|UniProtKB=P07001	P07001	pntA	PTHR10160:SF31	NAD(P) TRANSHYDROGENASE	NAD(P) TRANSHYDROGENASE SUBUNIT ALPHA	nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;binding#GO:0005488;small molecule binding#GO:0036094;purine nucleotide binding#GO:0017076;nucleoside phosphate binding#GO:1901265	organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;nucleotide metabolic process#GO:0009117	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0485|UniProtKB=P77454	P77454	glsA1	PTHR12544:SF48	GLUTAMINASE	GLUTAMINASE 1	hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824	cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436		hydrolase#PC00121	
ECOLI|EnsemblGenome=b3156|UniProtKB=P63417	P63417	yhbS	PTHR43617:SF2	L-AMINO ACID N-ACETYLTRANSFERASE	UPF0039 PROTEIN SLL0451	transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747			acetyltransferase#PC00038	
ECOLI|EnsemblGenome=b0306|UniProtKB=P77252	P77252	ykgE	PTHR30296:SF0	UNCHARACTERIZED PROTEIN YKGE	LACTATE UTILIZATION PROTEIN A			cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b2464|UniProtKB=P0A867	P0A867	talA	PTHR10683:SF16	TRANSALDOLASE	TRANSALDOLASE A	transferase activity#GO:0016740;catalytic activity#GO:0003824;transaldolase activity#GO:0004801;transketolase or transaldolase activity#GO:0016744	glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt, non-oxidative branch#GO:0009052;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;pentose-phosphate shunt#GO:0006098;glyceraldehyde-3-phosphate metabolic process#GO:0019682;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	lyase#PC00144;aldolase#PC00044;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0474|UniProtKB=P69441	P69441	adk	PTHR23359:SF263	NUCLEOTIDE KINASE	ADENYLATE KINASE	nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776	small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular process#GO:0009987;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleoside diphosphate metabolic process#GO:0009132	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	nucleotide kinase#PC00172;kinase#PC00137	De novo purine biosynthesis#P02738>Adenylate kinase#P02896
ECOLI|EnsemblGenome=b0777|UniProtKB=P12999	P12999	bioC	PTHR43464:SF107	METHYLTRANSFERASE	MALONYL-[ACYL-CARRIER PROTEIN] O-METHYLTRANSFERASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168			transferase#PC00220;methyltransferase#PC00155	
ECOLI|EnsemblGenome=b2585|UniProtKB=P23830	P23830	pssA	PTHR12586:SF2	CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE	CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE PSSA	transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity#GO:0016740;catalytic activity#GO:0003824		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	transferase#PC00220	
ECOLI|EnsemblGenome=b2062|UniProtKB=P0A930	P0A930	wza	PTHR33619:SF3	POLYSACCHARIDE EXPORT PROTEIN GFCE-RELATED	POLYSACCHARIDE EXPORT PROTEIN GFCE-RELATED	carbohydrate transmembrane transporter activity#GO:0015144;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215				
ECOLI|EnsemblGenome=b0125|UniProtKB=P0A9M2	P0A9M2	hpt	PTHR43340:SF1	HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE	HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE	glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;metal ion binding#GO:0046872;cation binding#GO:0043169;magnesium ion binding#GO:0000287;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;pentosyltransferase activity#GO:0016763	small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;purine nucleobase metabolic process#GO:0006144;IMP metabolic process#GO:0046040;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;IMP biosynthetic process#GO:0006188;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase metabolic process#GO:0009112	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111	Xanthine and guanine salvage pathway#P02788>Guanine phosphoribosyl transferase#P03245;Adenine and hypoxanthine salvage pathway#P02723>Hypoxanthine phosphoribosyl transferase#P02804;Xanthine and guanine salvage pathway#P02788>Xanthine phosphoribosyl transferase#P03247;Salvage pyrimidine ribonucleotides#P02775>Uracil phosphoribosyl  transferase#P03151
ECOLI|EnsemblGenome=b2235|UniProtKB=P69924	P69924	nrdB	PTHR23409:SF18	RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN	RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2				metabolite interconversion enzyme#PC00262;reductase#PC00198;oxidoreductase#PC00176	De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo purine biosynthesis#P02738>GDP reductase#P02909;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921
ECOLI|EnsemblGenome=b2610|UniProtKB=P0AGD7	P0AGD7	ffh	PTHR11564:SF5	SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54	SIGNAL RECOGNITION PARTICLE SUBUNIT SRP54, CHLOROPLASTIC				RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b1276|UniProtKB=P25516	P25516	acnA	PTHR11670:SF79	ACONITASE/IRON-RESPONSIVE ELEMENT FAMILY MEMBER	ACONITATE HYDRATASE A	iron-sulfur cluster binding#GO:0051536;lyase activity#GO:0016829;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;binding#GO:0005488;mRNA binding#GO:0003729;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824	aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	RNA metabolism protein#PC00031	Methylcitrate cycle#P02754>Aconitase#P03028
ECOLI|EnsemblGenome=b1711|UniProtKB=P06609	P06609	btuC	PTHR30472:SF29	FERRIC ENTEROBACTIN TRANSPORT SYSTEM PERMEASE PROTEIN	VITAMIN B12 IMPORT SYSTEM PERMEASE PROTEIN BTUC	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	establishment of localization#GO:0051234;import into cell#GO:0098657;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;iron coordination entity transport#GO:1901678;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;siderophore-iron import into cell#GO:0033214;nitrogen compound transport#GO:0071705;monoatomic ion homeostasis#GO:0050801;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;monoatomic cation transport#GO:0006812;localization#GO:0051179;siderophore-dependent iron import pathway#GO:0180060;cellular localization#GO:0051641;monoatomic ion transport#GO:0006811;iron ion transport#GO:0006826;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;vitamin transport#GO:0051180;intracellular iron ion homeostasis#GO:0006879;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;iron import into cell#GO:0033212	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b2533|UniProtKB=P0ADG4	P0ADG4	suhB	PTHR20854:SF4	INOSITOL MONOPHOSPHATASE	INOSITOL-1-MONOPHOSPHATASE-RELATED	hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787	cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;cell communication#GO:0007154	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	phosphatase#PC00181	
ECOLI|EnsemblGenome=b0082|UniProtKB=P60390	P60390	rsmH	PTHR11265:SF4	S-ADENOSYL-METHYLTRANSFERASE MRAW	RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE H	catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170	cellular component biogenesis#GO:0044085;rRNA base methylation#GO:0070475;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA modification#GO:0000154;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA methylation#GO:0001510;rRNA processing#GO:0006364		methyltransferase#PC00155;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0943|UniProtKB=P75860	P75860	ycbV	PTHR33420:SF25	FIMBRIAL SUBUNIT ELFA-RELATED	PROTEIN FIMF		cell adhesion#GO:0007155;cellular process#GO:0009987;single-species biofilm formation#GO:0044010;cell-substrate adhesion#GO:0031589	cell projection#GO:0042995;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2779|UniProtKB=P0A6P9	P0A6P9	eno	PTHR11902:SF1	ENOLASE	ENOLASE	hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824;phosphopyruvate hydratase activity#GO:0004634	ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139	catalytic complex#GO:1902494;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991	metabolite interconversion enzyme#PC00262;lyase#PC00144	Glycolysis#P00024>Enolase#P00678
ECOLI|EnsemblGenome=b2500|UniProtKB=P08179	P08179	purN	PTHR43369:SF3	PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE	PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741	ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;IMP metabolic process#GO:0046040;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;primary metabolic process#GO:0044238;IMP biosynthetic process#GO:0006188;organophosphate biosynthetic process#GO:0090407	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	transferase#PC00220	De novo purine biosynthesis#P02738>Phosphoribosylamine glycine ligase#P02908;De novo purine biosynthesis#P02738>Phosphoribosylglycinamide  formyltransferase#P02903;Tetrahydrofolate biosynthesis#P02742>Phosphoribosylglycinamide formyltransferase#P02944
ECOLI|EnsemblGenome=b2460|UniProtKB=P76555	P76555	eutQ	PTHR36169:SF2	ETHANOLAMINE UTILIZATION PROTEIN EUTQ	ACETATE KINASE EUTQ		metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987	intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229		
ECOLI|EnsemblGenome=b2676|UniProtKB=P37146	P37146	nrdF	PTHR23409:SF18	RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN	RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2				oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;reductase#PC00198	De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo purine biosynthesis#P02738>GDP reductase#P02909;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921
ECOLI|EnsemblGenome=b0893|UniProtKB=P0A8L1	P0A8L1	serS	PTHR43697:SF1	SERYL-TRNA SYNTHETASE	SERINE--TRNA LIGASE	catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101	translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	aminoacyl-tRNA synthetase#PC00047	
ECOLI|EnsemblGenome=b3635|UniProtKB=P05523	P05523	mutM	PTHR22993:SF9	FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE	FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE	endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on glycosyl bonds#GO:0016798;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;DNA N-glycosylase activity#GO:0019104	response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stress#GO:0006950;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974		DNA glycosylase#PC00010	
ECOLI|EnsemblGenome=b1387|UniProtKB=P77455	P77455	paaZ	PTHR43111:SF1	ALDEHYDE DEHYDROGENASE B-RELATED	ALDEHYDE DEHYDROGENASE B-RELATED	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824			oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402
ECOLI|EnsemblGenome=b1343|UniProtKB=P21693	P21693	dbpA	PTHR47959:SF26	ATP-DEPENDENT RNA HELICASE RHLE-RELATED	ATP-DEPENDENT RNA HELICASE DBPA	ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;catalytic activity#GO:0003824;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	RNA helicase#PC00032	
ECOLI|EnsemblGenome=b3005|UniProtKB=P0ABV2	P0ABV2	exbD	PTHR30558:SF9	EXBD MEMBRANE COMPONENT OF PMF-DRIVEN MACROMOLECULE IMPORT SYSTEM	BIOPOLYMER TRANSPORT PROTEIN EXBD			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b3045|UniProtKB=P0CF57	P0CF57	insD5	PTHR37936:SF3	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b3159|UniProtKB=P45475	P45475	ubiV	PTHR30217:SF11	PEPTIDASE U32 FAMILY	UBIQUINONE BIOSYNTHESIS HYDROXYLASE UBIV		small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283		protease#PC00190	
ECOLI|EnsemblGenome=b1858|UniProtKB=P0A9X1	P0A9X1	znuC	PTHR42734:SF9	METAL TRANSPORT SYSTEM ATP-BINDING PROTEIN TM_0124-RELATED	ZINC IMPORT ATP-BINDING PROTEIN ZNUC	ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804	response to metal ion#GO:0010038;response to chemical#GO:0042221;response to stimulus#GO:0050896	transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;ATPase dependent transmembrane transport complex#GO:0098533;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;ATP-binding cassette (ABC) transporter complex#GO:0043190;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227;primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0840|UniProtKB=P0ACK5	P0ACK5	deoR	PTHR30363:SF8	HTH-TYPE TRANSCRIPTIONAL REGULATOR SRLR-RELATED	DEOXYRIBOSE OPERON REPRESSOR	sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987	regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252		helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b1074|UniProtKB=P0ABX2	P0ABX2	flgC	PTHR30435:SF2	FLAGELLAR PROTEIN	FLAGELLAR BASAL-BODY ROD PROTEIN FLGC		bacterial-type flagellum-dependent swarming motility#GO:0071978;archaeal or bacterial-type flagellum-dependent cell motility#GO:0097588;cellular process#GO:0009987;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;bacterial-type flagellum-dependent cell motility#GO:0071973	membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;bacterial-type flagellum#GO:0009288;organelle#GO:0043226;cell projection#GO:0042995	structural protein#PC00211	
ECOLI|EnsemblGenome=b3034|UniProtKB=Q93K97	Q93K97	nudF	PTHR11839:SF5	UDP/ADP-SUGAR PYROPHOSPHATASE	ADP-RIBOSE PYROPHOSPHATASE	hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817	metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281		metabolite interconversion enzyme#PC00262;pyrophosphatase#PC00196	
ECOLI|EnsemblGenome=b1266|UniProtKB=P77766	P77766	rnm	PTHR42924:SF3	EXONUCLEASE	POLYMERASE_HISTIDINOL PHOSPHATASE N-TERMINAL DOMAIN-CONTAINING PROTEIN	DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;DNA exonuclease activity#GO:0004529;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527;5'-3' exonuclease activity#GO:0008409;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;hydrolase activity#GO:0016787				
ECOLI|EnsemblGenome=b3581|UniProtKB=P37678	P37678	sgbH	PTHR35039:SF3	3-KETO-L-GULONATE-6-PHOSPHATE DECARBOXYLASE SGBH-RELATED	3-KETO-L-GULONATE-6-PHOSPHATE DECARBOXYLASE SGBH-RELATED	lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824	small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;L-ascorbic acid metabolic process#GO:0019852;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152		metabolite interconversion enzyme#PC00262;decarboxylase#PC00089	
ECOLI|EnsemblGenome=b3765|UniProtKB=P22787	P22787	yifB	PTHR32039:SF7	MAGNESIUM-CHELATASE SUBUNIT CHLI	COMPETENCE PROTEIN COMM				metabolite interconversion enzyme#PC00262;ligase#PC00142	
ECOLI|EnsemblGenome=b0653|UniProtKB=P0AER5	P0AER5	gltK	PTHR30614:SF1	MEMBRANE COMPONENT OF AMINO ACID ABC TRANSPORTER	GLUTAMATE_ASPARTATE IMPORT PERMEASE PROTEIN GLTK	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171	neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234;localization#GO:0051179;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	amino acid transporter#PC00046	
ECOLI|EnsemblGenome=b3457|UniProtKB=P0AEX7	P0AEX7	livH	PTHR11795:SF371	BRANCHED-CHAIN AMINO ACID TRANSPORT SYSTEM PERMEASE PROTEIN LIVH	HIGH-AFFINITY BRANCHED-CHAIN AMINO ACID TRANSPORT SYSTEM PERMEASE PROTEIN LIVH	branched-chain amino acid transmembrane transporter activity#GO:0015658;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;L-amino acid transmembrane transporter activity#GO:0015179;carboxylic acid transmembrane transporter activity#GO:0046943;aromatic amino acid transmembrane transporter activity#GO:0015173	cellular process#GO:0009987;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;alanine transport#GO:0032328;branched-chain amino acid transport#GO:0015803;establishment of localization#GO:0051234;import into cell#GO:0098657;L-alpha-amino acid transmembrane transport#GO:1902475;carboxylic acid transmembrane transport#GO:1905039;L-leucine transport#GO:0015820;import across plasma membrane#GO:0098739;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;localization#GO:0051179	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227;secondary carrier transporter#PC00258;amino acid transporter#PC00046	
ECOLI|EnsemblGenome=b2569|UniProtKB=P60785	P60785	lepA	PTHR43512:SF4	TRANSLATION FACTOR GUF1-RELATED	TRANSLATION FACTOR GUF1 HOMOLOG, CHLOROPLASTIC	binding#GO:0005488;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021	biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of translation#GO:0045727;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of protein metabolic process#GO:0051247		translation initiation factor#PC00224	
ECOLI|Gene_OrderedLocusName=JW2076|UniProtKB=P69831	P69831	gatC	PTHR37324:SF2	PTS SYSTEM GALACTITOL-SPECIFIC EIIC COMPONENT	PTS SYSTEM GALACTITOL-SPECIFIC EIIC COMPONENT			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b4476|UniProtKB=P0AC96	P0AC96	gntU	PTHR30354:SF8	GNT FAMILY GLUCONATE TRANSPORTER	LOW-AFFINITY GLUCONATE TRANSPORTER	monocarboxylic acid transmembrane transporter activity#GO:0008028;carbohydrate transmembrane transporter activity#GO:0015144;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943	monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;carbohydrate transport#GO:0008643;carboxylic acid transmembrane transport#GO:1905039;carbohydrate transmembrane transport#GO:0034219;cellular process#GO:0009987	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	secondary carrier transporter#PC00258;transporter#PC00227	
ECOLI|EnsemblGenome=b2818|UniProtKB=P0A6C5	P0A6C5	argA	PTHR30602:SF12	AMINO-ACID ACETYLTRANSFERASE	AMINO-ACID ACETYLTRANSFERASE NAGS1, CHLOROPLASTIC-RELATED	acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824	arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;L-arginine biosynthetic process#GO:0006526;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436		acetyltransferase#PC00038	
ECOLI|EnsemblGenome=b1111|UniProtKB=P75952	P75952	comR	PTHR30055:SF214	HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR	HTH-TYPE TRANSCRIPTIONAL REPRESSOR COMR	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789		Tet repressor-like transcription factor#PC00266	
ECOLI|EnsemblGenome=b1080|UniProtKB=P0A6S3	P0A6S3	flgI	PTHR30381:SF0	FLAGELLAR P-RING PERIPLASMIC PROTEIN FLGI	FLAGELLAR P-RING PROTEIN		cilium or flagellum-dependent cell motility#GO:0001539;cellular process#GO:0009987;archaeal or bacterial-type flagellum-dependent cell motility#GO:0097588;bacterial-type flagellum-dependent cell motility#GO:0071973;cell motility#GO:0048870	bacterial-type flagellum#GO:0009288;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;cell projection#GO:0042995	structural protein#PC00211	
ECOLI|EnsemblGenome=b3399|UniProtKB=P64636	P64636	yrfG	PTHR43434:SF3	PHOSPHOGLYCOLATE PHOSPHATASE	GMP_IMP NUCLEOTIDASE YRFG	catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578	macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	metabolite interconversion enzyme#PC00262;phosphatase#PC00181	
ECOLI|EnsemblGenome=b0844|UniProtKB=P75809	P75809	ybjI	PTHR10000:SF53	PHOSPHOSERINE PHOSPHATASE	5-AMINO-6-(5-PHOSPHO-D-RIBITYLAMINO)URACIL PHOSPHATASE YBJI-RELATED	hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;magnesium ion binding#GO:0000287;cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787		intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	protein phosphatase#PC00195	
ECOLI|EnsemblGenome=b0103|UniProtKB=P0A6I9	P0A6I9	coaE	PTHR10695:SF46	DEPHOSPHO-COA KINASE-RELATED	DEPHOSPHO-COA KINASE DOMAIN-CONTAINING PROTEIN	phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772	organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407		kinase#PC00137;metabolite interconversion enzyme#PC00262	Coenzyme A biosynthesis#P02736>Pantetheine-phosphate adenyltransferase#P02886;Coenzyme A biosynthesis#P02736>Dephospho-CoA kinase#P02884
ECOLI|EnsemblGenome=b3139|UniProtKB=P42910	P42910	agaC	PTHR32502:SF8	N-ACETYLGALACTOSAMINE PERMEASE II COMPONENT-RELATED	N-ACETYLGALACTOSAMINE PERMEASE IIC COMPONENT 1		establishment of localization#GO:0051234;transmembrane transport#GO:0055085;import into cell#GO:0098657;localization#GO:0051179;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;transport#GO:0006810;carbohydrate transport#GO:0008643;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739;cellular process#GO:0009987	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b3923|UniProtKB=P0AAB8	P0AAB8	uspD	PTHR46268:SF23	STRESS RESPONSE PROTEIN NHAX	UNIVERSAL STRESS PROTEIN A-RELATED		response to stress#GO:0006950;response to stimulus#GO:0050896			
ECOLI|EnsemblGenome=b0003|UniProtKB=P00547	P00547	thrB	PTHR20861:SF1	HOMOSERINE/4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE	HOMOSERINE KINASE				metabolite interconversion enzyme#PC00262;kinase#PC00137	Threonine biosynthesis#P02781>Homoserine kinase#P03191
ECOLI|EnsemblGenome=b2158|UniProtKB=P62723	P62723	yeiH	PTHR30106:SF2	INNER MEMBRANE PROTEIN YEIH-RELATED	UPF0324 INNER MEMBRANE PROTEIN YEIH			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b2487|UniProtKB=P77329	P77329	hyfG	PTHR43485:SF1	HYDROGENASE-4 COMPONENT G	FORMATE HYDROGENLYASE SUBUNIT 5-RELATED		generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900;anaerobic electron transport chain#GO:0019645;anaerobic respiration#GO:0009061		metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2313|UniProtKB=P08550	P08550	cvpA	PTHR36926:SF1	COLICIN V PRODUCTION PROTEIN	COLICIN V PRODUCTION PROTEIN			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b0228|UniProtKB=Q47152	Q47152	rayT	PTHR36966:SF2	REP-ASSOCIATED TYROSINE TRANSPOSASE	REP-ASSOCIATED TYROSINE TRANSPOSASE	catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640	macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238		viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b0152|UniProtKB=P07822	P07822	fhuD	PTHR30532:SF30	IRON III  DICITRATE-BINDING PERIPLASMIC PROTEIN	IRON(3+)-HYDROXAMATE-BINDING PROTEIN FHUD		intracellular monoatomic ion homeostasis#GO:0006873;iron import into cell#GO:0033212;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular iron ion homeostasis#GO:0006879;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular localization#GO:0051641;siderophore-dependent iron import pathway#GO:0180060;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;siderophore-iron import into cell#GO:0033214;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;iron coordination entity transport#GO:1901678;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;import into cell#GO:0098657;establishment of localization#GO:0051234	cell envelope#GO:0030313;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;periplasmic space#GO:0042597;extracellular region#GO:0005576		
ECOLI|EnsemblGenome=b1971|UniProtKB=P76342	P76342	msrP	PTHR43032:SF3	PROTEIN-METHIONINE-SULFOXIDE REDUCTASE	PROTEIN-METHIONINE-SULFOXIDE REDUCTASE CATALYTIC SUBUNIT MSRP	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0328|UniProtKB=P75693	P75693	yahN	PTHR30086:SF21	ARGININE EXPORTER PROTEIN ARGO	AMINO ACID EFFLUX PROTEIN RHTB FAMILY	amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	localization#GO:0051179;establishment of localization#GO:0051234;amino acid transport#GO:0006865;transport#GO:0006810	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b1054|UniProtKB=P0ACV0	P0ACV0	lpxL	PTHR30606:SF9	LIPID A BIOSYNTHESIS LAUROYL ACYLTRANSFERASE	LIPID A BIOSYNTHESIS LAUROYLTRANSFERASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746	primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;lipid A biosynthetic process#GO:0009245;liposaccharide metabolic process#GO:1903509;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137	cellular anatomical structure#GO:0110165;membrane#GO:0016020	acyltransferase#PC00042;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3559|UniProtKB=P00961	P00961	glyS	PTHR30075:SF2	GLYCYL-TRNA SYNTHETASE	GLYCINE--TRNA LIGASE BETA SUBUNIT				aminoacyl-tRNA synthetase#PC00047	
ECOLI|EnsemblGenome=b2248|UniProtKB=P77732	P77732	rhmR	PTHR30136:SF2	HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY	BACTERIAL TRANSCRIPTIONAL REGULATOR	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b2472|UniProtKB=P0AED7	P0AED7	dapE	PTHR43270:SF8	BETA-ALA-HIS DIPEPTIDASE	SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE				metalloprotease#PC00153	Lysine biosynthesis#P02751>N-succinyl-diaminopimelate desuccinylase#P03012
ECOLI|EnsemblGenome=b2607|UniProtKB=P0A873	P0A873	trmD	PTHR46417:SF1	TRNA (GUANINE-N(1)-)-METHYLTRANSFERASE	TRNA (GUANINE-N(1)-)-METHYLTRANSFERASE	tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824	RNA methylation#GO:0001510;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;cellular process#GO:0009987	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b1136|UniProtKB=P08200	P08200	icd	PTHR43504:SF1	ISOCITRATE DEHYDROGENASE [NADP]	ISOCITRATE DEHYDROGENASE [NADP]	oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824	tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;cellular process#GO:0009987;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060		dehydrogenase#PC00092;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1404|UniProtKB=P0CF89	P0CF89	insI3	PTHR10948:SF23	TRANSPOSASE	TRANSPOSASE INSI FOR INSERTION SEQUENCE ELEMENT IS30A-RELATED	catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640	macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987		viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b2686|UniProtKB=P0AEJ0	P0AEJ0	emrB	PTHR23501:SF174	MAJOR FACILITATOR SUPERFAMILY	MULTIDRUG EXPORT PROTEIN EMRB-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b1092|UniProtKB=P0AAI9	P0AAI9	fabD	PTHR42681:SF7	MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL	MALONYL COA-ACYL CARRIER PROTEIN TRANSACYLASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747	lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b2309|UniProtKB=P0AEU0	P0AEU0	hisJ	PTHR35936:SF13	MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE F	HISTIDINE-BINDING PERIPLASMIC PROTEIN	amino acid binding#GO:0016597;binding#GO:0005488		extracellular region#GO:0005576;periplasmic space#GO:0042597;cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288		
ECOLI|EnsemblGenome=b0459|UniProtKB=P77791	P77791	maa	PTHR23416:SF23	SIALIC ACID SYNTHASE-RELATED	ACETYLTRANSFERASE C18B11.09C-RELATED	acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746			transferase#PC00220;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1816|UniProtKB=P0AEC0	P0AEC0	yoaE	PTHR22777:SF15	HEMOLYSIN-RELATED	UPF0053 INNER MEMBRANE PROTEIN YOAE			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|Gene_OrderedLocusName=JW5771|UniProtKB=P39212	P39212	insN2	PTHR33215:SF12	PROTEIN DISTAL ANTENNA	TRANSPOSASE INSN FOR INSERTION SEQUENCE ELEMENT IS911A-RELATED					
ECOLI|EnsemblGenome=b1530|UniProtKB=P27245	P27245	marR	PTHR33164:SF87	TRANSCRIPTIONAL REGULATOR, MARR FAMILY	MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN MARR		regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252		winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b1238|UniProtKB=P23331	P23331	tdk	PTHR11441:SF13	THYMIDINE KINASE	THYMIDINE KINASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;deoxynucleoside kinase activity#GO:0019136	nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate biosynthetic process#GO:0009124;small molecule metabolic process#GO:0044281;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	nucleotide kinase#PC00172;kinase#PC00137	Salvage pyrimidine deoxyribonucleotides#P02774>Deoxyuridine kinase#P03146;Salvage pyrimidine deoxyribonucleotides#P02774>Thymidine kinase#P03147
ECOLI|EnsemblGenome=b4266|UniProtKB=P0A9P9	P0A9P9	idnO	PTHR43669:SF9	5-KETO-D-GLUCONATE 5-REDUCTASE	5-KETO-D-GLUCONATE 5-REDUCTASE	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1783|UniProtKB=P0ACY3	P0ACY3	yeaG	PTHR30267:SF2	PROTEIN KINASE PRKA	SERINE_THREONINE KINASE YEAG	transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672			non-receptor serine/threonine protein kinase#PC00167	
ECOLI|EnsemblGenome=b3586|UniProtKB=P37683	P37683	yiaV	PTHR30386:SF18	MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP	INNER MEMBRANE PROTEIN YIAV-RELATED			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b3335|UniProtKB=P25960	P25960	gspO	PTHR30487:SF0	TYPE 4 PREPILIN-LIKE PROTEINS LEADER PEPTIDE-PROCESSING ENZYME	PREPILIN LEADER PEPTIDASE_N-METHYLTRANSFERASE-RELATED	catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	aspartic protease#PC00053;protein modifying enzyme#PC00260	
ECOLI|EnsemblGenome=b1985|UniProtKB=P76352	P76352	yeeO	PTHR43298:SF2	MULTIDRUG RESISTANCE PROTEIN NORM-RELATED	FMN_FAD EXPORTER YEEO-RELATED	carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b1932|UniProtKB=P76319	P76319	yedL	PTHR43877:SF5	AMINOALKYLPHOSPHONATE N-ACETYLTRANSFERASE-RELATED-RELATED	FAMILY N-ACETYLTRANSFERASE, PUTATIVE-RELATED	acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080				
ECOLI|EnsemblGenome=b0695|UniProtKB=P21865	P21865	kdpD	PTHR45569:SF1	SENSOR PROTEIN KDPD	SENSOR PROTEIN KDPD	protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphorelay sensor kinase activity#GO:0000155;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;protein histidine kinase activity#GO:0004673;catalytic activity, acting on a protein#GO:0140096		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b2524|UniProtKB=P0C0L9	P0C0L9	iscX	PTHR37532:SF1	PROTEIN ISCX	PROTEIN ISCX	binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;ferrous iron binding#GO:0008198;iron ion binding#GO:0005506				
ECOLI|EnsemblGenome=b0602|UniProtKB=P77216	P77216	ybdN	PTHR30083:SF0	TRANSCRIPTIONAL REGULATOR-RELATED	PHOSPHOADENOSINE PHOSPHOSULPHATE REDUCTASE DOMAIN-CONTAINING PROTEIN		response to abiotic stimulus#GO:0009628;cellular response to chemical stimulus#GO:0070887;response to oxygen levels#GO:0070482;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;response to chemical#GO:0042221			
ECOLI|EnsemblGenome=b3647|UniProtKB=P25772	P25772	ligB	PTHR47810:SF1	DNA LIGASE	DNA LIGASE B	catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on DNA#GO:0140097				
ECOLI|EnsemblGenome=b0477|UniProtKB=P0AEW6	P0AEW6	gsk	PTHR43085:SF37	HEXOKINASE FAMILY MEMBER	GUANOSINE-INOSINE KINASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773			transferase#PC00220;metabolite interconversion enzyme#PC00262;carbohydrate kinase#PC00065	
ECOLI|EnsemblGenome=b1475|UniProtKB=P0AAJ3	P0AAJ3	fdnH	PTHR43545:SF6	FORMATE DEHYDROGENASE, NITRATE-INDUCIBLE, IRON-SULFUR SUBUNIT	FORMATE DEHYDROGENASE, NITRATE-INDUCIBLE, IRON-SULFUR SUBUNIT	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;anaerobic respiration#GO:0009061;small molecule metabolic process#GO:0044281;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980	protein-containing complex#GO:0032991;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204	oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b4097|UniProtKB=P16678	P16678	phnK	PTHR42764:SF1	PHOSPHONATES UTILIZATION ATP-BINDING PROTEIN PHNK-RELATED	PHOSPHONATES UTILIZATION ATP-BINDING PROTEIN PHNK-RELATED		metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056		primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b4374|UniProtKB=P0A8Y1	P0A8Y1	yjjG	PTHR47478:SF1	PYRIMIDINE 5'-NUCLEOTIDASE YJJG	PYRIMIDINE 5'-NUCLEOTIDASE YJJG	nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787	nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;pyrimidine-containing compound metabolic process#GO:0072527;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793			
ECOLI|EnsemblGenome=b0586|UniProtKB=P11454	P11454	entF	PTHR45527:SF10	NONRIBOSOMAL PEPTIDE SYNTHETASE	ENTEROBACTIN SYNTHASE COMPONENT F	ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488	amino acid activation#GO:0043038;secondary metabolic process#GO:0019748;peptide metabolic process#GO:0006518;secondary metabolite biosynthetic process#GO:0044550;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b1274|UniProtKB=P06612	P06612	topA	PTHR42785:SF1	DNA TOPOISOMERASE, TYPE IA, CORE	DNA TOPOISOMERASE	macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097	chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;organelle organization#GO:0006996;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238		DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b2786|UniProtKB=P0AEC5	P0AEC5	barA	PTHR43719:SF74	TWO-COMPONENT HISTIDINE KINASE	SIGNAL TRANSDUCTION HISTIDINE-PROTEIN KINASE BARA	catalytic activity#GO:0003824;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;protein histidine kinase activity#GO:0004673;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;transferase activity#GO:0016740;phosphorelay sensor kinase activity#GO:0000155;kinase activity#GO:0016301;phosphoric ester hydrolase activity#GO:0042578;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672	cell communication#GO:0007154;intracellular signal transduction#GO:0035556;phosphorelay signal transduction system#GO:0000160;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	histidine kinase receptor of two-component system#PC00265;transmembrane signal receptor#PC00197	
ECOLI|EnsemblGenome=b4062|UniProtKB=P0A9E2	P0A9E2	soxS	PTHR47504:SF2	RIGHT ORIGIN-BINDING PROTEIN	REGULATORY PROTEIN SOXS	sequence-specific DNA binding#GO:0043565;protein binding#GO:0005515;DNA binding#GO:0003677;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;binding#GO:0005488;nucleic acid binding#GO:0003676	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119	
ECOLI|EnsemblGenome=b3903|UniProtKB=P32170	P32170	rhaA	PTHR30268:SF0	L-RHAMNOSE ISOMERASE	L-RHAMNOSE ISOMERASE	intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860	carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318		isomerase#PC00135	
ECOLI|EnsemblGenome=b4206|UniProtKB=P39310	P39310	ytfB	PTHR21666:SF289	PEPTIDASE-RELATED	CELL DIVISION PROTEIN YTFB				metalloprotease#PC00153;protease#PC00190	
ECOLI|EnsemblGenome=b4248|UniProtKB=P39332	P39332	yjgH	PTHR11803:SF44	2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA	RUTC FAMILY PROTEIN YJGH	catalytic activity#GO:0003824;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	deaminase#PC00088;metabolite interconversion enzyme#PC00262;hydrolase#PC00121	
ECOLI|EnsemblGenome=b3936|UniProtKB=P0A7M9	P0A7M9	rpmE	PTHR33280:SF6	50S RIBOSOMAL PROTEIN L31, CHLOROPLASTIC	LARGE RIBOSOMAL SUBUNIT PROTEIN BL31	structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198	biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152		translational protein#PC00263;ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b0044|UniProtKB=P68646	P68646	fixX	PTHR43082:SF1	FERREDOXIN-LIKE	FERREDOXIN-LIKE PROTEIN FIXX-RELATED				metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b4115|UniProtKB=P60061	P60061	adiC	PTHR42770:SF19	AMINO ACID TRANSPORTER-RELATED	ARGININE_AGMATINE ANTIPORTER	active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297;amino acid transmembrane transporter activity#GO:0015171		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227;amino acid transporter#PC00046;secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b1763|UniProtKB=P14294	P14294	topB	PTHR11390:SF27	PROKARYOTIC DNA TOPOISOMERASE	DNA TOPOISOMERASE 3	catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853	chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA damage response#GO:0006974;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304	replication fork#GO:0005657;chromosome#GO:0005694;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b2914|UniProtKB=P0A7Z0	P0A7Z0	rpiA	PTHR11934:SF1	RIBOSE-5-PHOSPHATE ISOMERASE	RIBOSE-5-PHOSPHATE ISOMERASE A	catalytic activity#GO:0003824;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;intramolecular oxidoreductase activity#GO:0016860;ribose-5-phosphate isomerase activity#GO:0004751;isomerase activity#GO:0016853	generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nucleobase-containing compound metabolic process#GO:0006139;glyceraldehyde-3-phosphate metabolic process#GO:0019682;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;pentose-phosphate shunt#GO:0006098;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt, non-oxidative branch#GO:0009052;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;isomerase#PC00135	Pentose phosphate pathway#P02762>Ribulose 5-P Isomerase#P03071
ECOLI|EnsemblGenome=b2431|UniProtKB=P76536	P76536	yfeX	PTHR30521:SF0	DEFERROCHELATASE/PEROXIDASE	DYP-TYPE PEROXIDASE FAMILY PROTEIN	binding#GO:0005488;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;tetrapyrrole binding#GO:0046906;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;heme binding#GO:0020037;oxidoreductase activity#GO:0016491		intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	peroxidase#PC00180	
ECOLI|EnsemblGenome=b0737|UniProtKB=P0ABU9	P0ABU9	tolQ	PTHR30625:SF3	PROTEIN TOLQ	TOL-PAL SYSTEM PROTEIN TOLQ		establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b4484|UniProtKB=P0AE85	P0AE85	cpxP	PTHR38102:SF2	PERIPLASMIC CHAPERONE SPY	PERIPLASMIC PROTEIN CPXP			cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;extracellular region#GO:0005576;periplasmic space#GO:0042597	chaperone#PC00072	
ECOLI|EnsemblGenome=b2303|UniProtKB=P0AC19	P0AC19	folX	PTHR42844:SF10	DIHYDRONEOPTERIN ALDOLASE 1-RELATED	DIHYDRONEOPTERIN TRIPHOSPHATE 2'-EPIMERASE	aldehyde-lyase activity#GO:0016832;isomerase activity#GO:0016853;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	metabolite interconversion enzyme#PC00262;aldolase#PC00044	
ECOLI|EnsemblGenome=b1413|UniProtKB=P43329	P43329	hrpA	PTHR18934:SF282	ATP-DEPENDENT RNA HELICASE	ATP-DEPENDENT RNA HELICASE HRPA	macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;isomerase activity#GO:0016853;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723			RNA metabolism protein#PC00031;RNA helicase#PC00032	
ECOLI|EnsemblGenome=b2755|UniProtKB=Q46896	Q46896	ygbT	PTHR34353:SF3	CRISPR-ASSOCIATED ENDONUCLEASE CAS1 1	CRISPR-ASSOCIATED ENDONUCLEASE CAS1	catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;endonuclease activity#GO:0004519	defense response to other organism#GO:0098542;response to other organism#GO:0051707;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;organelle organization#GO:0006996;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;defense response to symbiont#GO:0140546;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;defense response#GO:0006952;response to external stimulus#GO:0009605;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238			
ECOLI|EnsemblGenome=b4390|UniProtKB=P27278	P27278	nadR	PTHR37512:SF1	TRIFUNCTIONAL NAD BIOSYNTHESIS/REGULATOR PROTEIN NADR	NADR_TTD14 AAA DOMAIN-CONTAINING PROTEIN	nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772				
ECOLI|EnsemblGenome=b0464|UniProtKB=P0ACS9	P0ACS9	acrR	PTHR30055:SF175	HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR	HTH-TYPE TRANSCRIPTIONAL REGULATOR ACRR	double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789		Tet repressor-like transcription factor#PC00266	
ECOLI|EnsemblGenome=b1065|UniProtKB=P69367	P69367	mdtH	PTHR23517:SF2	RESISTANCE PROTEIN MDTM, PUTATIVE-RELATED-RELATED	MULTIDRUG RESISTANCE PROTEIN MDTH			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b1504|UniProtKB=P77789	P77789	ydeS	PTHR33420:SF25	FIMBRIAL SUBUNIT ELFA-RELATED	PROTEIN FIMF		cellular process#GO:0009987;cell adhesion#GO:0007155;single-species biofilm formation#GO:0044010;cell-substrate adhesion#GO:0031589	cell projection#GO:0042995;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1487|UniProtKB=P76128	P76128	ddpA	PTHR30290:SF84	PERIPLASMIC BINDING COMPONENT OF ABC TRANSPORTER	D,D-DIPEPTIDE-BINDING PERIPLASMIC PROTEIN DDPA-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	dipeptide transport#GO:0042938;establishment of localization#GO:0051234;localization#GO:0051179;oligopeptide transport#GO:0006857;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;transport#GO:0006810	cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;extracellular region#GO:0005576;periplasmic space#GO:0042597	ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227	
ECOLI|EnsemblGenome=b2049|UniProtKB=P24174	P24174	manC	PTHR46390:SF1	MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE	MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE	nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772	nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleotide-sugar metabolic process#GO:0009225;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238		transferase#PC00220	
ECOLI|EnsemblGenome=b0721|UniProtKB=P69054	P69054	sdhC	PTHR10978:SF21	SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT	SUCCINATE DEHYDROGENASE CYTOCHROME B556 SUBUNIT				dehydrogenase#PC00092	TCA cycle#P00051>Succinate Dehydrogenase#P01273
ECOLI|EnsemblGenome=b0555|UniProtKB=P78285	P78285	rrrD	PTHR38107:SF3	FAMILY NOT NAMED	LYSOZYME RRRD-RELATED					
ECOLI|EnsemblGenome=b1564|UniProtKB=P0C079	P0C079	relB	PTHR38781:SF1	ANTITOXIN DINJ-RELATED	ANTITOXIN DINJ-RELATED		RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987			
ECOLI|EnsemblGenome=b4137|UniProtKB=P69488	P69488	cutA	PTHR23419:SF8	DIVALENT CATION TOLERANCE CUTA-RELATED	FI09726P	metal ion binding#GO:0046872;cation binding#GO:0043169;copper ion binding#GO:0005507;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion binding#GO:0046914			primary active transporter#PC00068	
ECOLI|EnsemblGenome=b0223|UniProtKB=Q47147	Q47147	yafJ	PTHR42824:SF1	GLUTAMINE AMIDOTRANSFERASE	GLUTAMINE AMIDOTRANSFERASE YAFJ-RELATED				transferase#PC00220	
ECOLI|EnsemblGenome=b1618|UniProtKB=P0ACT6	P0ACT6	uidR	PTHR30055:SF223	HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR	HTH-TYPE TRANSCRIPTIONAL REGULATOR UIDR	double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794		Tet repressor-like transcription factor#PC00266	
ECOLI|EnsemblGenome=b1192|UniProtKB=P76008	P76008	ldcA	PTHR30237:SF7	MURAMOYLTETRAPEPTIDE CARBOXYPEPTIDASE	MUREIN TETRAPEPTIDE CARBOXYPEPTIDASE	hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;peptidase activity#GO:0008233;catalytic activity#GO:0003824	peptidoglycan turnover#GO:0009254;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycosaminoglycan metabolic process#GO:0030203;macromolecule metabolic process#GO:0043170;peptidoglycan metabolic process#GO:0000270;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	protease#PC00190;serine protease#PC00203	
ECOLI|EnsemblGenome=b2245|UniProtKB=P76469	P76469	rhmA	PTHR30502:SF5	2-KETO-3-DEOXY-L-RHAMNONATE ALDOLASE	2-KETO-3-DEOXY-L-RHAMNONATE ALDOLASE	aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824			metabolite interconversion enzyme#PC00262;aldolase#PC00044;lyase#PC00144	
ECOLI|EnsemblGenome=b0662|UniProtKB=P75728	P75728	ubiF	PTHR43876:SF10	UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL	3-DEMETHOXYUBIQUINOL 3-HYDROXYLASE	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705	small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;ketone metabolic process#GO:0042180;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281		oxygenase#PC00177;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3412|UniProtKB=P13001	P13001	bioH	PTHR43194:SF5	HYDROLASE ALPHA/BETA FOLD FAMILY	PIMELOYL-[ACYL-CARRIER PROTEIN] METHYL ESTER ESTERASE	catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787	monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;biotin metabolic process#GO:0006768;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330		hydrolase#PC00121	
ECOLI|EnsemblGenome=b3745|UniProtKB=P0ADN0	P0ADN0	viaA	PTHR36846:SF1	PROTEIN VIAA	REGULATORY PROTEIN VIAA			cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b1272|UniProtKB=P0AG14	P0AG14	sohB	PTHR42987:SF9	PEPTIDASE S49	PROTEASE SOHB-RELATED		protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	serine protease#PC00203;protease#PC00190	
ECOLI|EnsemblGenome=b2114|UniProtKB=P00959	P00959	metG	PTHR45765:SF13	METHIONINE--TRNA LIGASE	METHIONINE--TRNA LIGASE	catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874	primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263	
ECOLI|EnsemblGenome=b0531|UniProtKB=P77249	P77249	sfmC	PTHR30251:SF11	PILUS ASSEMBLY CHAPERONE	CHAPERONE PROTEIN FIMC-RELATED		metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467	cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313;extracellular region#GO:0005576;periplasmic space#GO:0042597	chaperone#PC00072	
ECOLI|EnsemblGenome=b0183|UniProtKB=P10442	P10442	rnhB	PTHR10954:SF18	RIBONUCLEASE H2 SUBUNIT A	RIBONUCLEASE HII	hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540	primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;mismatch repair#GO:0006298;DNA replication#GO:0006260;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170	catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991	endoribonuclease#PC00094	
ECOLI|EnsemblGenome=b2244|UniProtKB=P37014	P37014	yfaD	PTHR34611:SF2	INACTIVE RECOMBINATION-PROMOTING NUCLEASE-LIKE PROTEIN RPNE	INACTIVE RECOMBINATION-PROMOTING NUCLEASE-LIKE PROTEIN RPNE	hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536	cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170			
ECOLI|EnsemblGenome=b2834|UniProtKB=P0A9T4	P0A9T4	tas	PTHR43147:SF6	PROTEIN TAS	PROTEIN TAS			cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1988|UniProtKB=Q47005	Q47005	nac	PTHR30293:SF0	TRANSCRIPTIONAL REGULATORY PROTEIN NAC-RELATED	NITROGEN ASSIMILATION REGULATORY PROTEIN NAC	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of DNA-templated transcription initiation#GO:2000142;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794		DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b2185|UniProtKB=P68919	P68919	rplY	PTHR33284:SF1	RIBOSOMAL PROTEIN L25/GLN-TRNA SYNTHETASE, ANTI-CODON-BINDING DOMAIN-CONTAINING PROTEIN	RIBOSOMAL PROTEIN L25_GLN-TRNA SYNTHETASE, ANTI-CODON-BINDING DOMAIN-CONTAINING PROTEIN	rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723	metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058	ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737	ribosomal protein#PC00202;translational protein#PC00263	
ECOLI|EnsemblGenome=b2728|UniProtKB=P0AAM3	P0AAM3	hypC	PTHR35177:SF1	HYDROGENASE MATURATION FACTOR HYBG	HYDROGENASE MATURATION FACTOR HYPC	binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914;iron ion binding#GO:0005506;metal ion binding#GO:0046872;cation binding#GO:0043169	gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152			
ECOLI|EnsemblGenome=b0921|UniProtKB=P36566	P36566	cmoM	PTHR43464:SF102	METHYLTRANSFERASE	TRNA 5-CARBOXYMETHOXYURIDINE METHYLTRANSFERASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741			transferase#PC00220;methyltransferase#PC00155	
ECOLI|EnsemblGenome=b3846|UniProtKB=P21177	P21177	fadB	PTHR43612:SF9	TRIFUNCTIONAL ENZYME SUBUNIT ALPHA	FATTY ACID OXIDATION COMPLEX SUBUNIT ALPHA					
ECOLI|EnsemblGenome=b1256|UniProtKB=P0A915	P0A915	ompW	PTHR36920:SF2	FAMILY NOT NAMED	OUTER MEMBRANE PROTEIN W		cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085	cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;external encapsulating structure#GO:0030312;membrane#GO:0016020;cell outer membrane#GO:0009279;outer membrane#GO:0019867;extracellular region#GO:0005576		
ECOLI|EnsemblGenome=b4093|UniProtKB=P16691	P16691	phnO	PTHR43877:SF2	AMINOALKYLPHOSPHONATE N-ACETYLTRANSFERASE-RELATED-RELATED	AMINOALKYLPHOSPHONATE N-ACETYLTRANSFERASE					
ECOLI|EnsemblGenome=b1535|UniProtKB=P31129	P31129	dgcZ	PTHR45138:SF31	REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM	DIGUANYLATE CYCLASE DGCM-RELATED	catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772	negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular process#GO:0009987;negative regulation of biological process#GO:0048519;regulation of cell motility#GO:2000145;cell-substrate adhesion#GO:0031589;cell adhesion#GO:0007155;negative regulation of cellular process#GO:0048523;single-species biofilm formation#GO:0044010	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b3900|UniProtKB=P32155	P32155	frvA	PTHR47738:SF2	PTS SYSTEM FRUCTOSE-LIKE EIIA COMPONENT-RELATED	PTS SYSTEM FRUCTOSE-LIKE EIIA COMPONENT					
ECOLI|EnsemblGenome=b1155|UniProtKB=P09154	P09154	ymfS	PTHR34413:SF1	PROPHAGE TAIL FIBER ASSEMBLY PROTEIN HOMOLOG TFAE-RELATED-RELATED	CYTOPLASMIC PROTEIN				chaperone#PC00072	
ECOLI|EnsemblGenome=b0349|UniProtKB=P77044	P77044	mhpC	PTHR43689:SF8	HYDROLASE	2-HYDROXY-6-OXONONADIENEDIOATE_2-HYDROXY-6-OXONONATRIENEDIOATE HYDROLASE	catalytic activity#GO:0003824;hydrolase activity#GO:0016787			protein modifying enzyme#PC00260;serine protease#PC00203	
ECOLI|EnsemblGenome=b0091|UniProtKB=P17952	P17952	murC	PTHR43445:SF3	UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE-RELATED	UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE	ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879	aminoglycan metabolic process#GO:0006022;cell wall macromolecule metabolic process#GO:0044036;cell wall biogenesis#GO:0042546;glycosaminoglycan metabolic process#GO:0030203;aminoglycan biosynthetic process#GO:0006023;peptidoglycan biosynthetic process#GO:0009252;peptidoglycan-based cell wall biogenesis#GO:0009273;metabolic process#GO:0008152;peptidoglycan metabolic process#GO:0000270;carbohydrate derivative biosynthetic process#GO:1901137;glycosaminoglycan biosynthetic process#GO:0006024;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;cell wall macromolecule biosynthetic process#GO:0044038;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;cell wall organization or biogenesis#GO:0071554		ligase#PC00142	
ECOLI|EnsemblGenome=b1619|UniProtKB=P0AET8	P0AET8	hdhA	PTHR43618:SF21	7-ALPHA-HYDROXYSTEROID DEHYDROGENASE	7ALPHA-HYDROXYSTEROID DEHYDROGENASE	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491		cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b0854|UniProtKB=P31133	P31133	potF	PTHR30222:SF18	SPERMIDINE/PUTRESCINE-BINDING PERIPLASMIC PROTEIN	BIFUNCTIONAL POLYHYDROXYBUTYRATE SYNTHASE _ ABC TRANSPORTER PERIPLASMIC BINDING PROTEIN-RELATED	small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169	localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;nitrogen compound transport#GO:0071705	cell envelope#GO:0030313;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;periplasmic space#GO:0042597;extracellular region#GO:0005576		
ECOLI|EnsemblGenome=b3269|UniProtKB=P45767	P45767	yhdX	PTHR30614:SF37	MEMBRANE COMPONENT OF AMINO ACID ABC TRANSPORTER	AMINO-ACID ABC TRANSPORTER PERMEASE PROTEIN YHDX-RELATED	amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	transport#GO:0006810;amino acid transport#GO:0006865;localization#GO:0051179;establishment of localization#GO:0051234	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	amino acid transporter#PC00046	
ECOLI|EnsemblGenome=b1690|UniProtKB=P76197	P76197	ydiM	PTHR23514:SF3	BYPASS OF STOP CODON PROTEIN 6	BYPASS OF STOP CODON PROTEIN 6			cellular anatomical structure#GO:0110165;membrane#GO:0016020		
ECOLI|EnsemblGenome=b2894|UniProtKB=P0A8P8	P0A8P8	xerD	PTHR30349:SF90	PHAGE INTEGRASE-RELATED	TYROSINE RECOMBINASE XERD	catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097	nucleobase-containing compound metabolic process#GO:0006139;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;cell cycle process#GO:0022402;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;chromosome segregation#GO:0007059		viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b2435|UniProtKB=P36548	P36548	amiA	PTHR30404:SF2	N-ACETYLMURAMOYL-L-ALANINE AMIDASE	N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMIA	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810	cell cycle#GO:0007049;cellular process#GO:0009987;cell division#GO:0051301;cell cycle process#GO:0022402;reproductive process in single-celled organism#GO:0022413;reproductive process#GO:0022414;cytokinesis#GO:0000910;FtsZ-dependent cytokinesis#GO:0043093	extracellular region#GO:0005576;periplasmic space#GO:0042597;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313	hydrolase#PC00121	
ECOLI|EnsemblGenome=b1929|UniProtKB=P31064	P31064	yedE	PTHR30574:SF1	INNER MEMBRANE PROTEIN YEDE	THIOSULFATE TRANSPORTER TSUA-RELATED			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b0724|UniProtKB=P07014	P07014	sdhB	PTHR11921:SF29	SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN	SUCCINATE DEHYDROGENASE IRON-SULFUR SUBUNIT		respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152		oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1198|UniProtKB=P37349	P37349	dhaM	PTHR38594:SF1	PEP-DEPENDENT DIHYDROXYACETONE KINASE, PHOSPHORYL DONOR SUBUNIT DHAM	PEP-DEPENDENT DIHYDROXYACETONE KINASE, PHOSPHORYL DONOR SUBUNIT DHAM		primary metabolic process#GO:0044238;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975	catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991	transferase#PC00220;kinase#PC00137	
ECOLI|EnsemblGenome=b3343|UniProtKB=P45530	P45530	tusB	PTHR37526:SF1	PROTEIN TUSB	PROTEIN TUSB		tRNA wobble position uridine thiolation#GO:0002143;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA thio-modification#GO:0034227;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033	cytosol#GO:0005829;sulfurtransferase complex#GO:1990228;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b1190|UniProtKB=P29012	P29012	dadX	PTHR30511:SF0	ALANINE RACEMASE	ALANINE RACEMASE, CATABOLIC	binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;isomerase activity#GO:0016853;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824	amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	epimerase/racemase#PC00096	
ECOLI|EnsemblGenome=b1803|UniProtKB=P76254	P76254	yeaX	PTHR47354:SF1	NADH OXIDOREDUCTASE HCR	CARNITINE MONOOXYGENASE REDUCTASE SUBUNIT	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0714|UniProtKB=P50465	P50465	nei	PTHR42697:SF1	ENDONUCLEASE 8	ENDONUCLEASE 8	DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;DNA N-glycosylase activity#GO:0019104;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520	cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;base-excision repair#GO:0006284;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170			
ECOLI|EnsemblGenome=b3212|UniProtKB=P09831	P09831	gltB	PTHR11938:SF133	FAD NADPH DEHYDROGENASE/OXIDOREDUCTASE	FERREDOXIN-DEPENDENT GLUTAMATE SYNTHASE 1, CHLOROPLASTIC_MITOCHONDRIAL	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;homeostatic process#GO:0042592;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;small molecule biosynthetic process#GO:0044283;chemical homeostasis#GO:0048878;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;proteinogenic amino acid biosynthetic process#GO:0170038;cellular process#GO:0009987;response to nutrient levels#GO:0031667;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039		oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3349|UniProtKB=P0A9K9	P0A9K9	slyD	PTHR47861:SF3	FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD	FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD	catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;cis-trans isomerase activity#GO:0016859;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853	protein refolding#GO:0042026;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	chaperone#PC00072	
ECOLI|EnsemblGenome=b2792|UniProtKB=Q46919	Q46919	yqcC	PTHR39586:SF1	CYTOPLASMIC PROTEIN-RELATED	CYTOPLASMIC PROTEIN		cellular process#GO:0009987;single-species biofilm formation#GO:0044010			
ECOLI|EnsemblGenome=b2904|UniProtKB=P0A6T9	P0A6T9	gcvH	PTHR11715:SF44	GLYCINE CLEAVAGE SYSTEM H PROTEIN	GLYCINE CLEAVAGE SYSTEM H PROTEIN			cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b3182|UniProtKB=P24228	P24228	dacB	PTHR30023:SF0	D-ALANYL-D-ALANINE CARBOXYPEPTIDASE	PENICILLIN-SENSITIVE CARBOXYPEPTIDASE A	serine-type peptidase activity#GO:0008236;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233	macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;peptidoglycan metabolic process#GO:0000270;aminoglycan metabolic process#GO:0006022;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987		protein modifying enzyme#PC00260;serine protease#PC00203	
ECOLI|EnsemblGenome=b0092|UniProtKB=P07862	P07862	ddlB	PTHR23132:SF27	D-ALANINE--D-ALANINE LIGASE	D-ALANINE--D-ALANINE LIGASE B	catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879	cellular component biogenesis#GO:0044085;cell wall macromolecule biosynthetic process#GO:0044038;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cell wall organization or biogenesis#GO:0071554;biosynthetic process#GO:0009058;peptidoglycan metabolic process#GO:0000270;metabolic process#GO:0008152;peptidoglycan-based cell wall biogenesis#GO:0009273;glycosaminoglycan biosynthetic process#GO:0006024;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;carbohydrate derivative biosynthetic process#GO:1901137;glycosaminoglycan metabolic process#GO:0030203;aminoglycan biosynthetic process#GO:0006023;peptidoglycan biosynthetic process#GO:0009252;aminoglycan metabolic process#GO:0006022;cell wall biogenesis#GO:0042546;cell wall macromolecule metabolic process#GO:0044036	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;ligase#PC00142	Peptidoglycan biosynthesis#P02763>D-alanine-D-alanine ligase#P03091
ECOLI|EnsemblGenome=b1815|UniProtKB=P76261	P76261	pdeD	PTHR33121:SF83	CYCLIC DI-GMP PHOSPHODIESTERASE PDEF	CYCLIC DI-GMP PHOSPHODIESTERASE PDED-RELATED	hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788	regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121	
ECOLI|EnsemblGenome=b2544|UniProtKB=P76584	P76584	yphB	PTHR10091:SF45	ALDOSE-1-EPIMERASE	ALDOSE EPIMERASE FAMILY PROTEIN	isomerase activity#GO:0016853;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824	metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carbohydrate catabolic process#GO:0016052;glucose metabolic process#GO:0006006;organophosphate metabolic process#GO:0019637;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282		epimerase/racemase#PC00096	
ECOLI|EnsemblGenome=b1253|UniProtKB=P0A8Z0	P0A8Z0	yciA	PTHR11049:SF5	ACYL COENZYME A THIOESTER HYDROLASE	ACYL-COA THIOESTER HYDROLASE YCIA	hydrolase activity#GO:0016787;catalytic activity#GO:0003824;fatty acyl-CoA hydrolase activity#GO:0047617;deacylase activity#GO:0160215;acyl-CoA hydrolase activity#GO:0016289;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788	nucleobase-containing compound metabolic process#GO:0006139;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	esterase#PC00097	
ECOLI|EnsemblGenome=b1432|UniProtKB=P76102	P76102	insQ	PTHR30405:SF27	TRANSPOSASE	RNA-GUIDED DNA ENDONUCLEASE INSQ-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b0899|UniProtKB=P75835	P75835	ycaM	PTHR42770:SF15	AMINO ACID TRANSPORTER-RELATED	GLUTAMATE_GAMMA-AMINOBUTYRATE ANTIPORTER-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	secondary carrier transporter#PC00258;amino acid transporter#PC00046;transporter#PC00227	
ECOLI|EnsemblGenome=b4398|UniProtKB=P08368	P08368	creB	PTHR48111:SF6	REGULATOR OF RPOS	TRANSCRIPTIONAL REGULATORY PROTEIN CREB	sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;molecular transducer activity#GO:0060089;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677	regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993	winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b2762|UniProtKB=P17854	P17854	cysH	PTHR46509:SF1	PHOSPHOADENOSINE PHOSPHOSULFATE REDUCTASE	PHOSPHOADENOSINE PHOSPHOSULFATE REDUCTASE	catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491	cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790		transferase#PC00220;nucleotidyltransferase#PC00174	
ECOLI|EnsemblGenome=b0061|UniProtKB=P08203	P08203	araD	PTHR22789:SF15	FUCULOSE PHOSPHATE ALDOLASE	L-RIBULOSE-5-PHOSPHATE 4-EPIMERASE ARAD	isomerase activity#GO:0016853;aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857	carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;cellular process#GO:0009987	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	lyase#PC00144;aldolase#PC00044	Ascorbate degradation#P02729>L-ribulose-5-phosphate-4-epimerase#P02851;Pentose phosphate pathway#P02762>Ribulose 5-P Isomerase#P03071
ECOLI|EnsemblGenome=b0675|UniProtKB=P0AF24	P0AF24	nagD	PTHR19288:SF46	4-NITROPHENYLPHOSPHATASE-RELATED	HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2	catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578		cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	phosphatase#PC00181;hydrolase#PC00121	
ECOLI|EnsemblGenome=b3568|UniProtKB=P0AGI4	P0AGI4	xylH	PTHR32196:SF32	ABC TRANSPORTER PERMEASE PROTEIN YPHD-RELATED-RELATED	XYLOSE TRANSPORT SYSTEM PERMEASE PROTEIN XYLH			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b0579|UniProtKB=P0AAT2	P0AAT2	ybdF	PTHR35145:SF1	CYTOPLASMIC PROTEIN-RELATED	HYPOTHETICAL CYTOSOLIC PROTEIN					
ECOLI|EnsemblGenome=b2151|UniProtKB=P25748	P25748	galS	PTHR30146:SF109	LACI-RELATED TRANSCRIPTIONAL REPRESSOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR GALS-RELATED	transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556		helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218;Lambda repressor-like transcription factor#PC00245	
ECOLI|EnsemblGenome=b3876|UniProtKB=P32136	P32136	yihO	PTHR11328:SF43	MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN	SULFOQUINOVOSE IMPORTER-RELATED		localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	primary active transporter#PC00068	
ECOLI|EnsemblGenome=b2067|UniProtKB=P38097	P38097	dgcE	PTHR44757:SF4	DIGUANYLATE CYCLASE DGCP	DIGUANYLATE CYCLASE DGCE-RELATED	transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824			lyase#PC00144;cyclase#PC00079	
ECOLI|EnsemblGenome=b1719|UniProtKB=P0A8M3	P0A8M3	thrS	PTHR11451:SF62	THREONINE-TRNA LIGASE	THREONINE--TRNA LIGASE	catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640	translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	aminoacyl-tRNA synthetase#PC00047	
ECOLI|EnsemblGenome=b0824|UniProtKB=P75794	P75794	ybiY	PTHR30352:SF14	PYRUVATE FORMATE-LYASE-ACTIVATING ENZYME	PYRUVATE FORMATE-LYASE 3-ACTIVATING ENZYME-RELATED	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824				
ECOLI|EnsemblGenome=b0286|UniProtKB=P77165	P77165	paoA	PTHR45331:SF1	OXIDOREDUCTASE, IRON-SULPHUR BINDING SUBUNIT-RELATED-RELATED	ALDEHYDE OXIDOREDUCTASE IRON-SULFUR-BINDING SUBUNIT PAOA	catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536;oxidoreductase activity#GO:0016491		extracellular region#GO:0005576;periplasmic space#GO:0042597;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1220|UniProtKB=P39165	P39165	ychO	PTHR39576:SF1	ATTACHING AND EFFACING PROTEIN HOMOLOG-RELATED-RELATED	INVASIN			cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;membrane#GO:0016020;cell outer membrane#GO:0009279;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;outer membrane#GO:0019867		
ECOLI|EnsemblGenome=b3270|UniProtKB=P45768	P45768	yhdY	PTHR30614:SF41	MEMBRANE COMPONENT OF AMINO ACID ABC TRANSPORTER	INNER MEMBRANE AMINO-ACID ABC TRANSPORTER PERMEASE PROTEIN YHDY	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171	localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;amino acid transport#GO:0006865	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	amino acid transporter#PC00046	
ECOLI|EnsemblGenome=b4306|UniProtKB=P39367	P39367	yjhP	PTHR43464:SF3	METHYLTRANSFERASE	SAM-DEPENDENT METHYLTRANSFERASE	transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;catalytic activity#GO:0003824			methyltransferase#PC00155;transferase#PC00220	
ECOLI|EnsemblGenome=b3331|UniProtKB=P45761	P45761	gspJ	PTHR39583:SF2	TYPE II SECRETION SYSTEM PROTEIN J-RELATED	TYPE II SECRETION SYSTEM PROTEIN J		macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of localization#GO:0051234;protein secretion by the type II secretion system#GO:0015628;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;protein transmembrane transport#GO:0071806;transport#GO:0006810;export from cell#GO:0140352;protein localization to extracellular region#GO:0071692;protein secretion#GO:0009306;localization#GO:0051179;secretion#GO:0046903;transmembrane transport#GO:0055085;secretion by cell#GO:0032940;protein transport#GO:0015031	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;type II protein secretion system complex#GO:0015627;membrane#GO:0016020		
ECOLI|EnsemblGenome=b1641|UniProtKB=P0A905	P0A905	slyB	PTHR35603:SF1	FAMILY NOT NAMED	OUTER MEMBRANE LIPOPROTEIN SLYB			cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;membrane#GO:0016020;cell outer membrane#GO:0009279;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;outer membrane#GO:0019867		
ECOLI|EnsemblGenome=b1086|UniProtKB=P0AA39	P0AA39	rluC	PTHR21600:SF40	MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE	PSEUDOURIDYLATE SYNTHASE RPUSD2	isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866	RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254		RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b0518|UniProtKB=Q47208	Q47208	allF	PTHR11117:SF24	SUCCINYL-COA LIGASE SUBUNIT ALPHA	OXAMATE CARBAMOYLTRANSFERASE SUBUNIT ALLF	ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877	cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;ligase#PC00142	
ECOLI|EnsemblGenome=b0059|UniProtKB=P60240	P60240	rapA	PTHR10799:SF971	SNF2/RAD54 HELICASE FAMILY	HDA1 COMPLEX SUBUNIT 3	DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640	negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;heterochromatin formation#GO:0031507;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357		DNA helicase#PC00011;DNA metabolism protein#PC00009	Wnt signaling pathway#P00057>SWI/SNF#P01435
ECOLI|EnsemblGenome=b0272|UniProtKB=P77300	P77300	xynR	PTHR30136:SF7	HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY	HTH-TYPE TRANSCRIPTIONAL REGULATOR KDGR-RELATED	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789		winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b3072|UniProtKB=P50466	P50466	aer	PTHR43531:SF7	PROTEIN ICFG	AEROTAXIS RECEPTOR	transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089	chemotaxis#GO:0006935;response to chemical#GO:0042221;response to stimulus#GO:0050896;taxis#GO:0042330;response to external stimulus#GO:0009605;locomotion#GO:0040011	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b4148|UniProtKB=P69937	P69937	gdx	PTHR30561:SF24	SMR FAMILY PROTON-DEPENDENT DRUG EFFLUX TRANSPORTER SUGE	GUANIDINIUM EXPORTER	active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297	xenobiotic detoxification by transmembrane export across the plasma membrane#GO:1990961;cellular process#GO:0009987;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;response to chemical#GO:0042221;detoxification#GO:0098754;export from cell#GO:0140352;xenobiotic transport#GO:0042908;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b1950|UniProtKB=P33135	P33135	fliR	PTHR30065:SF8	FLAGELLAR BIOSYNTHETIC PROTEIN FLIR	FLAGELLAR BIOSYNTHETIC PROTEIN FLIR			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b3714|UniProtKB=P31466	P31466	adeP	PTHR43337:SF22	XANTHINE/URACIL PERMEASE C887.17-RELATED	ADENINE PERMEASE ADEP-RELATED	nucleobase transmembrane transporter activity#GO:0015205;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b4025|UniProtKB=P0A6T1	P0A6T1	pgi	PTHR11469:SF1	GLUCOSE-6-PHOSPHATE ISOMERASE	GLUCOSE-6-PHOSPHATE ISOMERASE	intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824;monosaccharide binding#GO:0048029;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;carbohydrate binding#GO:0030246;small molecule binding#GO:0036094;binding#GO:0005488	nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;ADP catabolic process#GO:0046032;carbohydrate biosynthetic process#GO:0016051;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;pyruvate metabolic process#GO:0006090;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate catabolic process#GO:1901292;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;nicotinamide nucleotide metabolic process#GO:0046496;gluconeogenesis#GO:0006094;ATP metabolic process#GO:0046034;oxoacid metabolic process#GO:0043436;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;ribonucleoside diphosphate metabolic process#GO:0009185;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;energy derivation by oxidation of organic compounds#GO:0015980;small molecule biosynthetic process#GO:0044283;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine nucleotide catabolic process#GO:0006195;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;glucose 6-phosphate metabolic process#GO:0051156;catabolic process#GO:0009056;purine ribonucleotide catabolic process#GO:0009154;hexose biosynthetic process#GO:0019319;nucleoside diphosphate catabolic process#GO:0009134	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	isomerase#PC00135;metabolite interconversion enzyme#PC00262	Pentose phosphate pathway#P02762>Glucose-P-Isomerase#P03080;Glycolysis#P00024>Phosphoglucose isomerase#P00674
ECOLI|EnsemblGenome=b1282|UniProtKB=P08245	P08245	yciH	PTHR12789:SF0	DENSITY-REGULATED PROTEIN HOMOLOG	DENSITY-REGULATED PROTEIN	protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488	macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;translation#GO:0006412;translational initiation#GO:0006413;cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	translation initiation factor#PC00224	
ECOLI|EnsemblGenome=b0156|UniProtKB=P0ACC3	P0ACC3	erpA	PTHR43011:SF7	IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL	IRON-SULFUR CLUSTER INSERTION PROTEIN ERPA	iron ion binding#GO:0005506;metal ion binding#GO:0046872;iron-sulfur cluster binding#GO:0051536;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914	metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;iron-sulfur cluster assembly#GO:0016226;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular component assembly#GO:0022607	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		
ECOLI|EnsemblGenome=b1949|UniProtKB=P0AC07	P0AC07	fliQ	PTHR34040:SF2	FLAGELLAR BIOSYNTHETIC PROTEIN FLIQ	FLAGELLAR BIOSYNTHETIC PROTEIN FLIQ		cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;bacterial-type flagellum assembly#GO:0044780			
ECOLI|EnsemblGenome=b3114|UniProtKB=P42632	P42632	tdcE	PTHR30191:SF7	FORMATE ACETYLTRANSFERASE	PFL-LIKE ENZYME TDCE	acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	transferase#PC00220;acetyltransferase#PC00038	
ECOLI|EnsemblGenome=b2738|UniProtKB=Q46890	Q46890	otnC	PTHR22789:SF0	FUCULOSE PHOSPHATE ALDOLASE	3-OXO-TETRONATE 4-PHOSPHATE DECARBOXYLASE	carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829	carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996		aldolase#PC00044;lyase#PC00144	
ECOLI|EnsemblGenome=b1982|UniProtKB=P0AE12	P0AE12	amn	PTHR43691:SF6	URIDINE PHOSPHORYLASE	AMP NUCLEOSIDASE			cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2316|UniProtKB=P0A9Q5	P0A9Q5	accD	PTHR42995:SF7	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA, CHLOROPLASTIC	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA		organophosphate biosynthetic process#GO:0090407;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;negative regulation of protein metabolic process#GO:0051248;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;nucleoside phosphate biosynthetic process#GO:1901293;monocarboxylic acid biosynthetic process#GO:0072330;regulation of biosynthetic process#GO:0009889;acyl-CoA metabolic process#GO:0006637;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;fatty acid metabolic process#GO:0006631;post-transcriptional regulation of gene expression#GO:0010608;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;biological regulation#GO:0065007;fatty acid biosynthetic process#GO:0006633;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of translation#GO:0006417;organophosphate metabolic process#GO:0019637;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;negative regulation of translation#GO:0017148;small molecule metabolic process#GO:0044281;negative regulation of metabolic process#GO:0009892;monocarboxylic acid metabolic process#GO:0032787;negative regulation of biological process#GO:0048519;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of macromolecule biosynthetic process#GO:0010558;sulfur compound metabolic process#GO:0006790;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494		
ECOLI|EnsemblGenome=b0069|UniProtKB=P33595	P33595	sgrR	PTHR30290:SF72	PERIPLASMIC BINDING COMPONENT OF ABC TRANSPORTER	HTH-TYPE TRANSCRIPTIONAL REGULATOR SGRR	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	transport#GO:0006810;peptide transport#GO:0015833;localization#GO:0051179;establishment of localization#GO:0051234		transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b3810|UniProtKB=P23305	P23305	yigA	PTHR38765:SF1	DUF484 DOMAIN-CONTAINING PROTEIN	DUF484 DOMAIN-CONTAINING PROTEIN					
ECOLI|EnsemblGenome=b1591|UniProtKB=P69853	P69853	dmsD	PTHR34227:SF6	CHAPERONE PROTEIN YCDY	TAT PROOFREADING CHAPERONE DMSD		metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	chaperone#PC00072	
ECOLI|EnsemblGenome=b1212|UniProtKB=P0ACC1	P0ACC1	prmC	PTHR18895:SF75	HEMK METHYLTRANSFERASE	RELEASE FACTOR GLUTAMINE METHYLTRANSFERASE	N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096	macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex disassembly#GO:0032984;protein biosynthetic process#GO:0160307;translation#GO:0006412;translational termination#GO:0006415;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538		protein modifying enzyme#PC00260	
ECOLI|EnsemblGenome=b3215|UniProtKB=P28722	P28722	yhcA	PTHR30251:SF3	PILUS ASSEMBLY CHAPERONE	FIMBRIAL CHAPERONE		primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170	extracellular region#GO:0005576;periplasmic space#GO:0042597;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313	chaperone#PC00072	
ECOLI|EnsemblGenome=b3541|UniProtKB=P0AAG0	P0AAG0	dppD	PTHR43297:SF16	OLIGOPEPTIDE TRANSPORT ATP-BINDING PROTEIN APPD	DIPEPTIDE TRANSPORT ATP-BINDING PROTEIN DPPD	dipeptide transmembrane transporter activity#GO:0071916;oligopeptide transmembrane transporter activity#GO:0035673;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857			ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227	
ECOLI|EnsemblGenome=b3656|UniProtKB=P31434	P31434	yicI	PTHR43053:SF4	GLYCOSIDASE FAMILY 31	RE74917P				metabolite interconversion enzyme#PC00262;glucosidase#PC00108;hydrolase#PC00121	
ECOLI|EnsemblGenome=b3077|UniProtKB=P0AC73	P0AC73	ebgC	PTHR34986:SF4	EVOLVED BETA-GALACTOSIDASE SUBUNIT BETA	EVOLVED BETA-GALACTOSIDASE SUBUNIT BETA-RELATED		single-species biofilm formation#GO:0044010;cellular process#GO:0009987	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	galactosidase#PC00104;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b4142|UniProtKB=P0A6F9	P0A6F9	groES	PTHR10772:SF58	10 KDA HEAT SHOCK PROTEIN	CO-CHAPERONIN GROES	binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;protein-folding chaperone binding#GO:0051087;cation binding#GO:0043169;metal ion binding#GO:0046872;protein binding#GO:0005515	macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238		chaperonin#PC00073	
ECOLI|EnsemblGenome=b1882|UniProtKB=P0AE67	P0AE67	cheY	PTHR43228:SF27	TWO-COMPONENT RESPONSE REGULATOR	CHEMOTAXIS PROTEIN CHEY	catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;molecular transducer activity#GO:0060089;phosphoprotein phosphatase activity#GO:0004721	intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;phosphorelay signal transduction system#GO:0000160;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896		helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b0417|UniProtKB=P0AGG0	P0AGG0	thiL	PTHR30270:SF0	THIAMINE-MONOPHOSPHATE KINASE	THIAMINE-MONOPHOSPHATE KINASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, phosphate group as acceptor#GO:0016776	biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152		kinase#PC00137	
ECOLI|Gene_OrderedLocusName=JW1363|UniProtKB=P76071	P76071	insH5	PTHR35604:SF2	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097	cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b4304|UniProtKB=P39365	P39365	sgcC	PTHR37324:SF4	PTS SYSTEM GALACTITOL-SPECIFIC EIIC COMPONENT	PERMEASE IIC COMPONENT-RELATED			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b1261|UniProtKB=P0A879	P0A879	trpB	PTHR48077:SF3	TRYPTOPHAN SYNTHASE-RELATED	TRYPTOPHAN SYNTHASE	carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824	proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;amine metabolic process#GO:0009308;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;aromatic amino acid biosynthetic process#GO:0009073;indole-containing compound metabolic process#GO:0042430;carboxylic acid biosynthetic process#GO:0046394	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165		Tryptophan biosynthesis#P02783>Tryptophan synthase B#P03208
ECOLI|EnsemblGenome=b0723|UniProtKB=P0AC41	P0AC41	sdhA	PTHR11632:SF87	SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT	SUCCINATE DEHYDROGENASE FLAVOPROTEIN SUBUNIT	oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;anaerobic respiration#GO:0009061;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;cell periphery#GO:0071944;respiratory chain complex II (succinate dehydrogenase)#GO:0045273;catalytic complex#GO:1902494	dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b0035|UniProtKB=P39206	P39206	caiE	PTHR13061:SF65	DYNACTIN SUBUNIT P25	CARNITINE OPERON PROTEIN CAIE-RELATED	acyl-CoA hydrolase activity#GO:0016289;deacylase activity#GO:0160215;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787	cellular process#GO:0009987;carnitine metabolic process#GO:0009437;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152		microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156	
ECOLI|EnsemblGenome=b2144|UniProtKB=P0AFY2	P0AFY2	sanA	PTHR30336:SF0	INNER MEMBRANE PROTEIN, PROBABLE PERMEASE	PEPTIDOGLYCAN BIOSYNTHESIS REGULATOR SANA		response to xenobiotic stimulus#GO:0009410;response to chemical#GO:0042221;response to stimulus#GO:0050896	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b0929|UniProtKB=P02931	P02931	ompF	PTHR34501:SF2	PROTEIN YDDL-RELATED	OUTER MEMBRANE PORIN F-RELATED	passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;channel activity#GO:0015267		membrane protein complex#GO:0098796;membrane#GO:0016020;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0891|UniProtKB=P61316	P61316	lolA	PTHR35869:SF2	OUTER-MEMBRANE LIPOPROTEIN CARRIER PROTEIN	OUTER-MEMBRANE LIPOPROTEIN CARRIER PROTEIN		macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization within membrane#GO:0051668;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein transport#GO:0015031	cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313;extracellular region#GO:0005576;periplasmic space#GO:0042597	transfer/carrier protein#PC00219	
ECOLI|EnsemblGenome=b1494|UniProtKB=P31828	P31828	pqqL	PTHR11851:SF49	METALLOPROTEASE	ZINC PROTEASE PQQL-RELATED				metalloprotease#PC00153;protease#PC00190	
ECOLI|EnsemblGenome=b3020|UniProtKB=Q46863	Q46863	ygiS	PTHR30290:SF86	PERIPLASMIC BINDING COMPONENT OF ABC TRANSPORTER	PERIPLASMIC OLIGOPEPTIDE-BINDING PROTEIN OPPA-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	localization#GO:0051179;establishment of localization#GO:0051234;peptide transport#GO:0015833;transport#GO:0006810	extracellular region#GO:0005576;periplasmic space#GO:0042597;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313	transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b1433|UniProtKB=P76103	P76103	ydcO	PTHR30199:SF0	MFS FAMILY TRANSPORTER, PREDICTED SUBSTRATE BENZOATE	INNER MEMBRANE PROTEIN YDCO			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b2922|UniProtKB=P0ADS6	P0ADS6	yggE	PTHR34387:SF1	SLR1258 PROTEIN	EXPORTED PROTEIN		response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stress#GO:0006950			
ECOLI|EnsemblGenome=b2558|UniProtKB=P0AGC5	P0AGC5	mltF	PTHR35936:SF32	MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE F	MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE F	peptidoglycan lytic transglycosylase activity#GO:0008933;carbon-oxygen lyase activity, acting on polysaccharides#GO:0016837;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835	carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycosaminoglycan metabolic process#GO:0030203;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;glycosaminoglycan catabolic process#GO:0006027;metabolic process#GO:0008152;peptidoglycan metabolic process#GO:0000270;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057	cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;membrane#GO:0016020;cell outer membrane#GO:0009279;external encapsulating structure#GO:0030312;outer membrane#GO:0019867;extracellular region#GO:0005576		
ECOLI|EnsemblGenome=b2907|UniProtKB=P25534	P25534	ubiH	PTHR43876:SF8	UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL	2-OCTAPRENYL-6-METHOXYPHENOL HYDROXYLASE	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;oxidoreductase activity#GO:0016491	biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;ubiquinone biosynthetic process#GO:0006744;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ketone metabolic process#GO:0042180;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152		oxidoreductase#PC00176;oxygenase#PC00177	
ECOLI|EnsemblGenome=b0628|UniProtKB=P60716	P60716	lipA	PTHR10949:SF39	LIPOYL SYNTHASE	LIPOYL SYNTHASE					Lipoate_biosynthesis#P02750>Lipoate synthase#P03004
ECOLI|EnsemblGenome=b1873|UniProtKB=P52005	P52005	torY	PTHR30333:SF3	CYTOCHROME C-TYPE PROTEIN	CYTOCHROME C-TYPE PROTEIN TORY		anaerobic respiration#GO:0009061;anaerobic electron transport chain#GO:0019645;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152		transporter#PC00227;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b1373|UniProtKB=P77163	P77163	tfaR	PTHR34413:SF2	PROPHAGE TAIL FIBER ASSEMBLY PROTEIN HOMOLOG TFAE-RELATED-RELATED	PROPHAGE TAIL FIBER ASSEMBLY PROTEIN HOMOLOG TFAE-RELATED				chaperone#PC00072	
ECOLI|EnsemblGenome=b1545|UniProtKB=P77170	P77170	pinQ	PTHR30461:SF2	DNA-INVERTASE FROM LAMBDOID PROPHAGE	SERINE RECOMBINASE PINE-RELATED	catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097	DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139			
ECOLI|Gene_OrderedLocusName=b3534|UniProtKB=P37655	P37655	bcsQ	PTHR43384:SF6	SEPTUM SITE-DETERMINING PROTEIN MIND HOMOLOG, CHLOROPLASTIC-RELATED	SEPTUM SITE-DETERMINING PROTEIN MIND HOMOLOG, CHLOROPLASTIC	heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167		side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b1185|UniProtKB=P0A6M2	P0A6M2	dsbB	PTHR36570:SF2	DISULFIDE BOND FORMATION PROTEIN B	DISULFIDE BOND FORMATION PROTEIN B	catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667	protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987			
ECOLI|EnsemblGenome=b1852|UniProtKB=P0AC53	P0AC53	zwf	PTHR23429:SF25	GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE  G6PD	GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;glucose-6-phosphate dehydrogenase activity#GO:0004345;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491	pentose-phosphate shunt#GO:0006098;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;nucleotide metabolic process#GO:0009117;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;hexose metabolic process#GO:0019318;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;pentose-phosphate shunt, oxidative branch#GO:0009051;generation of precursor metabolites and energy#GO:0006091;glucose metabolic process#GO:0006006;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b4123|UniProtKB=P0ABN9	P0ABN9	dcuB	PTHR36106:SF3	ANAEROBIC C4-DICARBOXYLATE TRANSPORTER DCUB	ANAEROBIC C4-DICARBOXYLATE TRANSPORTER DCUB	active transmembrane transporter activity#GO:0022804;succinate transmembrane transporter activity#GO:0015141;dicarboxylic acid transmembrane transporter activity#GO:0005310;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297;carboxylic acid transmembrane transporter activity#GO:0046943;C4-dicarboxylate transmembrane transporter activity#GO:0015556	metabolic process#GO:0008152;organic acid transport#GO:0015849;C4-dicarboxylate transport#GO:0015740;transport#GO:0006810;carboxylic acid transport#GO:0046942;generation of precursor metabolites and energy#GO:0006091;establishment of localization#GO:0051234;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;localization#GO:0051179;cellular process#GO:0009987;anaerobic respiration#GO:0009061;dicarboxylic acid transport#GO:0006835	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b0176|UniProtKB=P0AEH1	P0AEH1	rseP	PTHR42837:SF2	REGULATOR OF SIGMA-E PROTEASE RSEP	REGULATOR OF SIGMA-E PROTEASE RSEP	catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096			protease#PC00190;metalloprotease#PC00153	
ECOLI|EnsemblGenome=b0574|UniProtKB=P77239	P77239	cusB	PTHR30097:SF4	CATION EFFLUX SYSTEM PROTEIN CUSB	CATION EFFLUX SYSTEM PROTEIN CUSB		cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;copper ion transmembrane transport#GO:0035434;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812	cellular anatomical structure#GO:0110165;cell envelope#GO:0030313	secondary carrier transporter#PC00258;transporter#PC00227	
ECOLI|EnsemblGenome=b1299|UniProtKB=P0A9U6	P0A9U6	puuR	PTHR46797:SF11	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR PUUR	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794		Lambda repressor-like transcription factor#PC00245	
ECOLI|EnsemblGenome=b1794|UniProtKB=P76245	P76245	dgcP	PTHR45138:SF31	REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM	DIGUANYLATE CYCLASE DGCM-RELATED	transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740	regulation of cell motility#GO:2000145;cell-substrate adhesion#GO:0031589;negative regulation of cellular process#GO:0048523;single-species biofilm formation#GO:0044010;cell adhesion#GO:0007155;regulation of cellular process#GO:0050794;regulation of locomotion#GO:0040012;negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;cellular process#GO:0009987;regulation of biological process#GO:0050789	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b1117|UniProtKB=P75957	P75957	lolD	PTHR24220:SF689	IMPORT ATP-BINDING PROTEIN	LIPOPROTEIN-RELEASING SYSTEM ATP-BINDING PROTEIN LOLD	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	transport#GO:0006810;localization within membrane#GO:0051668;transmembrane transport#GO:0055085;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;protein localization to extracellular region#GO:0071692;cellular process#GO:0009987	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b2392|UniProtKB=P0A769	P0A769	mntH	PTHR11706:SF33	SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER	DIVALENT METAL CATION TRANSPORTER MNTH	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075	iron ion transmembrane transport#GO:0034755;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;iron ion transport#GO:0006826;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;metal ion transport#GO:0030001	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	secondary carrier transporter#PC00258;transporter#PC00227	
ECOLI|EnsemblGenome=b1291|UniProtKB=P0AAH4	P0AAH4	sapD	PTHR43297:SF4	OLIGOPEPTIDE TRANSPORT ATP-BINDING PROTEIN APPD	PUTRESCINE EXPORT SYSTEM ATP-BINDING PROTEIN SAPD	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;polyamine transmembrane transporter activity#GO:0015203			transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b2752|UniProtKB=P21156	P21156	cysD	PTHR43196:SF1	SULFATE ADENYLYLTRANSFERASE SUBUNIT 2	SULFATE ADENYLYLTRANSFERASE SUBUNIT 2	nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772	cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;sulfur compound metabolic process#GO:0006790;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494	metabolite interconversion enzyme#PC00262;nucleotidyltransferase#PC00174	
ECOLI|EnsemblGenome=b2334|UniProtKB=P76500	P76500	yfcQ	PTHR33420:SF33	FIMBRIAL SUBUNIT ELFA-RELATED	MINOR FIMBRIAL SUBUNIT		cellular process#GO:0009987;cell adhesion#GO:0007155;single-species biofilm formation#GO:0044010;cell-substrate adhesion#GO:0031589	cell projection#GO:0042995;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0253|UniProtKB=P75678	P75678	ykfA	PTHR42714:SF2	TRNA MODIFICATION GTPASE GTPBP3	TRNA MODIFICATION GTPASE MNME		RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA metabolic process#GO:0016070;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA methylation#GO:0030488;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	RNA methyltransferase#PC00033;RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b1849|UniProtKB=P33221	P33221	purT	PTHR43055:SF1	FORMATE-DEPENDENT PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE	FORMATE-DEPENDENT PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE			cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	transferase#PC00220	
ECOLI|Gene_OrderedLocusName=JW5839|UniProtKB=P33924	P33924	yejO	PTHR35037:SF7	C-TERMINAL REGION OF AIDA-LIKE PROTEIN	AUTOTRANSPORTER PROTEIN					
ECOLI|EnsemblGenome=b3464|UniProtKB=P10121	P10121	ftsY	PTHR43134:SF11	SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA	SIGNAL RECOGNITION PARTICLE RECEPTOR FTSY	ribonucleoprotein complex binding#GO:0043021;hydrolase activity#GO:0016787;protein-containing complex binding#GO:0044877;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817	establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;protein targeting#GO:0006605;localization#GO:0051179	cellular anatomical structure#GO:0110165;membrane#GO:0016020	G-protein#PC00020;protein-binding activity modulator#PC00095	
ECOLI|EnsemblGenome=b2050|UniProtKB=P32057	P32057	wcaI	PTHR12526:SF633	GLYCOSYLTRANSFERASE	COLANIC ACID BIOSYNTHESIS GLYCOSYL TRANSFERASE WCAI-RELATED	glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740			glycosyltransferase#PC00111;transferase#PC00220	
ECOLI|EnsemblGenome=b3470|UniProtKB=P0A890	P0A890	tusA	PTHR33279:SF2	SULFUR CARRIER PROTEIN YEDF-RELATED	SULFUR CARRIER PROTEIN TUSA				transfer/carrier protein#PC00219	
ECOLI|EnsemblGenome=b1786|UniProtKB=P76237	P76237	dgcJ	PTHR45138:SF22	REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM	DIGUANYLATE CYCLASE DGCJ-RELATED	catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772	cell adhesion#GO:0007155;negative regulation of cellular process#GO:0048523;single-species biofilm formation#GO:0044010;cell-substrate adhesion#GO:0031589;regulation of cell motility#GO:2000145;cellular process#GO:0009987;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;regulation of cellular process#GO:0050794	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b3957|UniProtKB=P23908	P23908	argE	PTHR43808:SF1	ACETYLORNITHINE DEACETYLASE	ACETYLORNITHINE DEACETYLASE	hydrolase activity#GO:0016787;deacetylase activity#GO:0019213;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacylase activity#GO:0160215;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811	primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;L-arginine biosynthetic process#GO:0006526		deacetylase#PC00087;metabolite interconversion enzyme#PC00262	Arginine biosynthesis#P02728>N-actetylornithine deacetylase#P02847
ECOLI|EnsemblGenome=b4259|UniProtKB=P28905	P28905	holC	PTHR38767:SF1	DNA POLYMERASE III SUBUNIT CHI	DNA POLYMERASE III SUBUNIT CHI		regulation of DNA replication#GO:0006275;positive regulation of metabolic process#GO:0009893;positive regulation of DNA metabolic process#GO:0051054;regulation of biological process#GO:0050789;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA replication#GO:0045740;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of DNA-templated DNA replication initiation#GO:0030174		DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b4135|UniProtKB=P0ACU7	P0ACU7	yjdC	PTHR47506:SF1	TRANSCRIPTIONAL REGULATORY PROTEIN	HTH-TYPE TRANSCRIPTIONAL REGULATOR YJDC		negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794		Tet repressor-like transcription factor#PC00266	
ECOLI|EnsemblGenome=b2916|UniProtKB=P0A8S1	P0A8S1	argP	PTHR30579:SF2	TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR ARGP	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789		gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b2070|UniProtKB=P76393	P76393	yegI	PTHR13954:SF6	IRE1-RELATED	NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE				tyrosine protein kinase receptor#PC00233;transmembrane signal receptor#PC00197	Alzheimer disease-presenilin pathway#P00004>Ire-1#P00144;Alzheimer disease-presenilin pathway#P00004>Ire-1 C-terminal fragment#P00125;Alzheimer disease-presenilin pathway#P00004>Ire-1 N-terminal fragment#P00110
ECOLI|EnsemblGenome=b2929|UniProtKB=P11663	P11663	fumE	PTHR37941:SF1	FUMARASE E-RELATED	FUMARASE E-RELATED		negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355			
ECOLI|EnsemblGenome=b3631|UniProtKB=P25740	P25740	waaG	PTHR12526:SF641	GLYCOSYLTRANSFERASE	LIPOPOLYSACCHARIDE GLUCOSYLTRANSFERASE WAAG	catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757			glycosyltransferase#PC00111;transferase#PC00220	
ECOLI|EnsemblGenome=b1200|UniProtKB=P76015	P76015	dhaK	PTHR28629:SF4	TRIOKINASE/FMN CYCLASE	TRIOKINASE_FMN CYCLASE	phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740	cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;carbohydrate catabolic process#GO:0016052	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	cyclase#PC00079	
ECOLI|EnsemblGenome=b0979|UniProtKB=P26458	P26458	appB	PTHR43141:SF1	CYTOCHROME BD2 SUBUNIT II	CYTOCHROME BD-II UBIQUINOL OXIDASE SUBUNIT 2	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on diphenols and related substances as donors#GO:0016679;catalytic activity#GO:0003824	respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646	membrane#GO:0016020;cell periphery#GO:0071944;catalytic complex#GO:1902494;cytochrome complex#GO:0070069;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b4251|UniProtKB=P39334	P39334	bdcR	PTHR30055:SF200	HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR	HTH-TYPE TRANSCRIPTIONAL REPRESSOR BDCR	sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488	biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889		Tet repressor-like transcription factor#PC00266	
ECOLI|EnsemblGenome=b0902|UniProtKB=P0A9N4	P0A9N4	pflA	PTHR30352:SF5	PYRUVATE FORMATE-LYASE-ACTIVATING ENZYME	PYRUVATE FORMATE-LYASE 1-ACTIVATING ENZYME	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b0951|UniProtKB=P43671	P43671	pqiB	PTHR30462:SF2	INTERMEMBRANE TRANSPORT PROTEIN PQIB-RELATED	INTERMEMBRANE TRANSPORT PROTEIN PQIB		cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b2221|UniProtKB=P76458	P76458	atoD	PTHR13707:SF63	KETOACID-COENZYME A TRANSFERASE	ACETATE COA-TRANSFERASE SUBUNIT ALPHA	transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740			metabolite interconversion enzyme#PC00262;transferase#PC00220	
ECOLI|EnsemblGenome=b3102|UniProtKB=P42620	P42620	yqjG	PTHR32419:SF33	GLUTATHIONYL-HYDROQUINONE REDUCTASE	GLUTATHIONYL-HYDROQUINONE REDUCTASE YQJG	oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491		intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176;reductase#PC00198	
ECOLI|EnsemblGenome=b2140|UniProtKB=P33371	P33371	dusC	PTHR11082:SF26	TRNA-DIHYDROURIDINE SYNTHASE	TRNA-DIHYDROURIDINE(16) SYNTHASE				RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b2950|UniProtKB=P52052	P52052	yggR	PTHR30486:SF18	TWITCHING MOTILITY PROTEIN PILT	TYPE IV PILUS RETRACTION ATPASE YGGR-RELATED	ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b0478|UniProtKB=P39830	P39830	ybaL	PTHR42751:SF1	SODIUM/HYDROGEN EXCHANGER FAMILY/TRKA DOMAIN PROTEIN	CATION_PROTON ANTIPORTER YBAL-RELATED			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227;secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b1789|UniProtKB=P0ACY6	P0ACY6	yeaL	PTHR38452:SF1	UPF0756 MEMBRANE PROTEIN YEAL	UPF0756 MEMBRANE PROTEIN YEAL			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b2253|UniProtKB=P77690	P77690	arnB	PTHR30244:SF41	TRANSAMINASE	UDP-4-AMINO-4-DEOXY-L-ARABINOSE--OXOGLUTARATE AMINOTRANSFERASE	ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;transaminase activity#GO:0008483;heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824;transferase activity#GO:0016740	polysaccharide metabolic process#GO:0005976;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975;carbohydrate biosynthetic process#GO:0016051;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;polysaccharide biosynthetic process#GO:0000271		transaminase#PC00216	
ECOLI|EnsemblGenome=b1872|UniProtKB=P46923	P46923	torZ	PTHR43742:SF10	TRIMETHYLAMINE-N-OXIDE REDUCTASE	TRIMETHYLAMINE-N-OXIDE REDUCTASE 2	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;metabolic process#GO:0008152;anaerobic respiration#GO:0009061;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980	extracellular region#GO:0005576;periplasmic space#GO:0042597;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313	reductase#PC00198	
ECOLI|EnsemblGenome=b3610|UniProtKB=P0AC62	P0AC62	grxC	PTHR45694:SF14	GLUTAREDOXIN 2	GLUTAREDOXIN-RELATED	oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036	cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to oxidative stress#GO:0034599;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3241|UniProtKB=P46482	P46482	aaeA	PTHR30367:SF12	P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT AAEA-RELATED	P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT AAEA	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179			
ECOLI|EnsemblGenome=b1883|UniProtKB=P07330	P07330	cheB	PTHR42872:SF7	PROTEIN-GLUTAMATE METHYLESTERASE/PROTEIN-GLUTAMINE GLUTAMINASE	PROTEIN-GLUTAMATE METHYLESTERASE_PROTEIN-GLUTAMINE GLUTAMINASE	catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787	signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;taxis#GO:0042330;response to chemical#GO:0042221;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;locomotion#GO:0040011;chemotaxis#GO:0006935;cell communication#GO:0007154;response to external stimulus#GO:0009605		metabolite interconversion enzyme#PC00262;hydrolase#PC00121	
ECOLI|EnsemblGenome=b1714|UniProtKB=P08312	P08312	pheS	PTHR11538:SF105	PHENYLALANYL-TRNA SYNTHETASE	PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT	catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098	amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	aminoacyl-tRNA synthetase#PC00047	
ECOLI|EnsemblGenome=b3813|UniProtKB=P03018	P03018	uvrD	PTHR11070:SF2	UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER	DNA HELICASE II	ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543	DNA damage response#GO:0006974;DNA recombination#GO:0006310;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;recombinational repair#GO:0000725;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;DNA helicase complex#GO:0033202;cytosol#GO:0005829;catalytic complex#GO:1902494	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b1315|UniProtKB=P77503	P77503	ycjS	PTHR43249:SF1	UDP-N-ACETYL-2-AMINO-2-DEOXY-D-GLUCURONATE OXIDASE	D-GLUCOSIDE 3-DEHYDROGENASE	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616			metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b2188|UniProtKB=P0AD27	P0AD27	pbgA	PTHR43108:SF10	N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER	INNER MEMBRANE PROTEIN PBGA		glycoprotein metabolic process#GO:0009100;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	hydrolase#PC00121	
ECOLI|EnsemblGenome=b0066|UniProtKB=P31548	P31548	thiQ	PTHR42781:SF1	SPERMIDINE/PUTRESCINE IMPORT ATP-BINDING PROTEIN POTA	THIAMINE IMPORT ATP-BINDING PROTEIN THIQ	ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227	
ECOLI|EnsemblGenome=b4288|UniProtKB=P15029	P15029	fecD	PTHR30472:SF37	FERRIC ENTEROBACTIN TRANSPORT SYSTEM PERMEASE PROTEIN	FE(3+) DICITRATE TRANSPORT SYSTEM PERMEASE PROTEIN FECD-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	intracellular monoatomic ion homeostasis#GO:0006873;iron import into cell#GO:0033212;intracellular iron ion homeostasis#GO:0006879;metal ion transport#GO:0030001;homeostatic process#GO:0042592;iron ion transport#GO:0006826;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular localization#GO:0051641;siderophore-dependent iron import pathway#GO:0180060;monoatomic ion transport#GO:0006811;monoatomic ion homeostasis#GO:0050801;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;siderophore-iron import into cell#GO:0033214;iron coordination entity transport#GO:1901678;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b1374|UniProtKB=P0ADI0	P0ADI0	pinR	PTHR30461:SF2	DNA-INVERTASE FROM LAMBDOID PROPHAGE	SERINE RECOMBINASE PINE-RELATED	catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640	nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170			
ECOLI|EnsemblGenome=b1791|UniProtKB=P76242	P76242	nimT	PTHR23523:SF3	MAJOR FACILITATOR SUPERFAMILY (MFS) TRANSPORTER-RELATED	2-NITROIMIDAZOLE TRANSPORTER		response to antibiotic#GO:0046677;response to stimulus#GO:0050896;response to chemical#GO:0042221	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b2380|UniProtKB=P0AA93	P0AA93	ypdA	PTHR34220:SF7	SENSOR HISTIDINE KINASE YPDA	SENSOR HISTIDINE KINASE YPDA				transmembrane signal receptor#PC00197;histidine kinase receptor of two-component system#PC00265	
ECOLI|EnsemblGenome=b3291|UniProtKB=P0A742	P0A742	mscL	PTHR30266:SF2	MECHANOSENSITIVE CHANNEL MSCL	LARGE-CONDUCTANCE MECHANOSENSITIVE CHANNEL	passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267	localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;transport#GO:0006810	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b3981|UniProtKB=P0AG96	P0AG96	secE	PTHR33910:SF1	PROTEIN TRANSLOCASE SUBUNIT SECE	PROTEIN TRANSLOCASE SUBUNIT SECE	transmembrane protein transporter activity#GO:0008320;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;transport#GO:0006810;protein transmembrane transport#GO:0071806;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b2924|UniProtKB=P0C0S1	P0C0S1	mscS	PTHR30221:SF1	SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL	SMALL-CONDUCTANCE MECHANOSENSITIVE CHANNEL				ion channel#PC00133	
ECOLI|EnsemblGenome=b2765|UniProtKB=P65870	P65870	queD	PTHR12589:SF9	PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE	6-CARBOXY-5,6,7,8-TETRAHYDROPTERIN SYNTHASE	lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830	metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;tRNA wobble base modification#GO:0002097;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400			
ECOLI|EnsemblGenome=b2532|UniProtKB=P0AE01	P0AE01	trmJ	PTHR42786:SF2	TRNA/RRNA METHYLTRANSFERASE	TRNA (CYTIDINE_URIDINE-2'-O-)-METHYLTRANSFERASE TRMJ		tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	RNA metabolism protein#PC00031;RNA methyltransferase#PC00033	
ECOLI|EnsemblGenome=b1342|UniProtKB=P64423	P64423	zntB	PTHR46494:SF3	CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)	ZINC TRANSPORT PROTEIN ZNTB	cation binding#GO:0043169;magnesium ion binding#GO:0000287;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;magnesium ion transmembrane transporter activity#GO:0015095;ion binding#GO:0043167;transition metal ion transmembrane transporter activity#GO:0046915;small molecule binding#GO:0036094;binding#GO:0005488;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	primary active transporter#PC00068	
ECOLI|EnsemblGenome=b3157|UniProtKB=P64599	P64599	ubiT	PTHR10094:SF25	STEROL CARRIER PROTEIN 2  SCP-2  FAMILY PROTEIN	SCP2 STEROL-BINDING DOMAIN-CONTAINING PROTEIN 1			cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	transfer/carrier protein#PC00219	
ECOLI|EnsemblGenome=b2616|UniProtKB=P05824	P05824	recN	PTHR11059:SF0	DNA REPAIR PROTEIN RECN	DNA REPAIR PROTEIN RECN		response to stimulus#GO:0050896;response to stress#GO:0006950;cellular process#GO:0009987;SOS response#GO:0009432;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554;DNA damage response#GO:0006974	intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;bacterial nucleoid#GO:0043590;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoid#GO:0009295	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b0618|UniProtKB=P77390	P77390	citC	PTHR40599:SF2	[CITRATE [PRO-3S]-LYASE] LIGASE	[CITRATE [PRO-3S]-LYASE] LIGASE	ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877				
ECOLI|EnsemblGenome=b2371|UniProtKB=P76518	P76518	yfdE	PTHR48207:SF5	SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE	CAIB_BAIF COA-TRANSFERASE FAMILY PROTEIN DDB_G0269880				metabolite interconversion enzyme#PC00262;transferase#PC00220	Coenzyme A linked carnitine metabolism#P02732>L-carnitine dehydratase#P02864;Carnitine metabolism#P02733>Carnitine dehydratase#P02866
ECOLI|EnsemblGenome=b2712|UniProtKB=P30131	P30131	hypF	PTHR42959:SF1	CARBAMOYLTRANSFERASE	CARBAMOYLTRANSFERASE HYPF	cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;zinc ion binding#GO:0008270;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740	metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604		transferase#PC00220	
ECOLI|EnsemblGenome=b3549|UniProtKB=P05100	P05100	tag	PTHR30037:SF4	DNA-3-METHYLADENINE GLYCOSYLASE 1	DNA-3-METHYLADENINE GLYCOSYLASE I				DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b3755|UniProtKB=P31475	P31475	yieP	PTHR43537:SF44	TRANSCRIPTIONAL REGULATOR, GNTR FAMILY	GNTR-FAMLY TRANSCRIPTIONAL REGULATOR	double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889		winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b3496|UniProtKB=P36837	P36837	dtpB	PTHR11654:SF102	OLIGOPEPTIDE TRANSPORTER-RELATED	DIPEPTIDE AND TRIPEPTIDE PERMEASE B	monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:proton symporter activity#GO:0015295;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;tripeptide transmembrane transporter activity#GO:0042937;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;oligopeptide transmembrane transporter activity#GO:0035673;dipeptide transmembrane transporter activity#GO:0071916;proton transmembrane transporter activity#GO:0015078	transport#GO:0006810;dipeptide transport#GO:0042938;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;oligopeptide transport#GO:0006857;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;oligopeptide transmembrane transport#GO:0035672	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b2330|UniProtKB=P39199	P39199	prmB	PTHR47806:SF1	50S RIBOSOMAL PROTEIN L3 GLUTAMINE METHYLTRANSFERASE	RIBOSOMAL PROTEIN UL3 GLUTAMINE METHYLTRANSFERASE	catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	protein modifying enzyme#PC00260	
ECOLI|EnsemblGenome=b2061|UniProtKB=P0AAB2	P0AAB2	wzb	PTHR11717:SF31	LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE	LOW MOLECULAR WEIGHT PROTEIN-TYROSINE-PHOSPHATASE ETP-RELATED	phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725			protein phosphatase#PC00195	
ECOLI|EnsemblGenome=b3194|UniProtKB=P64606	P64606	mlaE	PTHR30188:SF4	ABC TRANSPORTER PERMEASE PROTEIN-RELATED	INTERMEMBRANE PHOSPHOLIPID TRANSPORT SYSTEM PERMEASE PROTEIN MLAE		macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;lipid transport#GO:0006869;organophosphate ester transport#GO:0015748;transport#GO:0006810;lipid localization#GO:0010876;establishment of localization#GO:0051234;localization#GO:0051179	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b3113|UniProtKB=P0AGL2	P0AGL2	tdcF	PTHR11803:SF58	2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA	2-IMINOBUTANOATE_2-IMINOPROPANOATE DEAMINASE-RELATED	catalytic activity#GO:0003824;deaminase activity#GO:0019239;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	hydrolase#PC00121;metabolite interconversion enzyme#PC00262;deaminase#PC00088	
ECOLI|EnsemblGenome=b0254|UniProtKB=Q57083	Q57083	perR	PTHR30537:SF58	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR PERR	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355		helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b3175|UniProtKB=P0AG99	P0AG99	secG	PTHR34182:SF1	PROTEIN-EXPORT MEMBRANE PROTEIN SECG	PROTEIN-EXPORT MEMBRANE PROTEIN SECG	transmembrane protein transporter activity#GO:0008320;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular transport#GO:0046907;protein transport#GO:0015031;intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b0729|UniProtKB=P0AGE9	P0AGE9	sucD	PTHR11117:SF27	SUCCINYL-COA LIGASE SUBUNIT ALPHA	SUCCINATE--COA LIGASE [ADP-FORMING] SUBUNIT ALPHA	ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877	primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;cellular process#GO:0009987;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;catalytic complex#GO:1902494	metabolite interconversion enzyme#PC00262;ligase#PC00142	TCA cycle#P00051>Succinyl CoA Synthetase#P01274
ECOLI|EnsemblGenome=b2920|UniProtKB=P52043	P52043	scpC	PTHR43609:SF1	ACETYL-COA HYDROLASE	ACETYL-COA HYDROLASE	hydrolase activity#GO:0016787;transferase activity, transferring sulphur-containing groups#GO:0016782;acyl-CoA hydrolase activity#GO:0016289;thiolester hydrolase activity#GO:0016790;transferase activity#GO:0016740;catalytic activity#GO:0003824;deacylase activity#GO:0160215;hydrolase activity, acting on ester bonds#GO:0016788	small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987		hydrolase#PC00121	
ECOLI|EnsemblGenome=b0652|UniProtKB=P0AAG3	P0AAG3	gltL	PTHR43166:SF39	AMINO ACID IMPORT ATP-BINDING PROTEIN	GLUTAMATE_ASPARTATE IMPORT ATP-BINDING PROTEIN GLTL	transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227	
ECOLI|EnsemblGenome=b2647|UniProtKB=P52143	P52143	ypjA	PTHR12338:SF5	AUTOTRANSPORTER	ANTIGEN 43-RELATED				protease#PC00190	
ECOLI|EnsemblGenome=b3345|UniProtKB=P45532	P45532	tusD	PTHR34874:SF3	PROTEIN YCHN	SULFURTRANSFERASE TUSD	molecular carrier activity#GO:0140104	tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble position uridine thiolation#GO:0002143;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;tRNA thio-modification#GO:0034227;macromolecule modification#GO:0043412;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033	cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;sulfurtransferase complex#GO:1990228;cytoplasm#GO:0005737;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b1443|UniProtKB=P0AFR9	P0AFR9	ydcV	PTHR43357:SF4	INNER MEMBRANE ABC TRANSPORTER PERMEASE PROTEIN YDCV	INNER MEMBRANE ABC TRANSPORTER PERMEASE PROTEIN YDCV				primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b2421|UniProtKB=P16703	P16703	cysM	PTHR10314:SF162	CYSTATHIONINE BETA-SYNTHASE	CYSTEINE SYNTHASE B		proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	lyase#PC00144;metabolite interconversion enzyme#PC00262	Cysteine biosynthesis#P02737>O-Acetylserine-lyase#P02887
ECOLI|EnsemblGenome=b2267|UniProtKB=P0AEH3	P0AEH3	elaA	PTHR13355:SF25	GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE	PROTEIN ELAA	acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;catalytic activity#GO:0003824			metabolite interconversion enzyme#PC00262;acetyltransferase#PC00038	
ECOLI|EnsemblGenome=b3566|UniProtKB=P37387	P37387	xylF	PTHR30036:SF1	D-XYLOSE-BINDING PERIPLASMIC PROTEIN	D-XYLOSE-BINDING PERIPLASMIC PROTEIN	binding#GO:0005488;carbohydrate binding#GO:0030246		cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313;extracellular region#GO:0005576;periplasmic space#GO:0042597		
ECOLI|EnsemblGenome=b1444|UniProtKB=P77674	P77674	patD	PTHR11699:SF313	ALDEHYDE DEHYDROGENASE-RELATED	GAMMA-AMINOBUTYRALDEHYDE DEHYDROGENASE	aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	cellular process#GO:0009987;amine catabolic process#GO:0009310;amine metabolic process#GO:0009308;metabolic process#GO:0008152;catabolic process#GO:0009056		dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	Ornithine degradation#P02758>Aminobutyraldehyde dehydrogenase#P03055;5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402
ECOLI|EnsemblGenome=b1594|UniProtKB=P50456	P50456	mlc	PTHR18964:SF178	ROK (REPRESSOR, ORF, KINASE) FAMILY	DNA-BINDING TRANSCRIPTIONAL REPRESSOR MLC	binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677	nucleic acid biosynthetic process#GO:0141187;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA-templated transcription#GO:0006351;gene expression#GO:0010467		winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b2899|UniProtKB=P67153	P67153	yqfA	PTHR20855:SF3	ADIPOR/PROGESTIN RECEPTOR-RELATED	LD03007P				G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197	
ECOLI|EnsemblGenome=b0437|UniProtKB=P0A6G7	P0A6G7	clpP	PTHR10381:SF70	ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT	ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT	ATP-dependent activity#GO:0140657;enzyme binding#GO:0019899;serine-type peptidase activity#GO:0008236;binding#GO:0005488;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;protein binding#GO:0005515;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252	catabolic process#GO:0009056;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057	protein-containing complex#GO:0032991;catalytic complex#GO:1902494	serine protease#PC00203	
ECOLI|EnsemblGenome=b0138|UniProtKB=P37018	P37018	yadM	PTHR33420:SF33	FIMBRIAL SUBUNIT ELFA-RELATED	MINOR FIMBRIAL SUBUNIT		cellular process#GO:0009987;cell adhesion#GO:0007155;single-species biofilm formation#GO:0044010;cell-substrate adhesion#GO:0031589	cell projection#GO:0042995;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1334|UniProtKB=P0A9E5	P0A9E5	fnr	PTHR24567:SF75	CRP FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN	FUMARATE AND NITRATE REDUCTION REGULATORY PROTEIN	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110		cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b1410|UniProtKB=P76092	P76092	ynbC	PTHR11614:SF195	PHOSPHOLIPASE-RELATED	ESTERASE_LIPASE 1-RELATED	hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788		cellular anatomical structure#GO:0110165;membrane#GO:0016020	phospholipase#PC00186;lipase#PC00143	
ECOLI|EnsemblGenome=b1749|UniProtKB=P09030	P09030	xthA	PTHR43250:SF2	EXODEOXYRIBONUCLEASE III	EXODEOXYRIBONUCLEASE III	DNA exonuclease activity#GO:0004529;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;3'-5'-DNA exonuclease activity#GO:0008296;hydrolase activity#GO:0016787	cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stress#GO:0006950;response to stimulus#GO:0050896	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b0366|UniProtKB=Q47538	Q47538	tauB	PTHR42788:SF18	TAURINE IMPORT ATP-BINDING PROTEIN-RELATED	TAURINE IMPORT ATP-BINDING PROTEIN TAUB				primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b1595|UniProtKB=P77559	P77559	ynfL	PTHR30346:SF17	TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED	LYSR FAMILY TRANSCRIPTIONAL REGULATOR	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789	protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991	winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b3442|UniProtKB=P46855	P46855	yhhZ	PTHR34319:SF7	MAJOR EXPORTED PROTEIN	HCP1 FAMILY MEMBER YHHZ					
ECOLI|EnsemblGenome=b2580|UniProtKB=P12295	P12295	ung	PTHR11264:SF0	URACIL-DNA GLYCOSYLASE	URACIL-DNA GLYCOSYLASE	catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA N-glycosylase activity#GO:0019104	macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;response to stress#GO:0006950;primary metabolic process#GO:0044238		DNA glycosylase#PC00010	
ECOLI|EnsemblGenome=b0905|UniProtKB=P75838	P75838	ycaO	PTHR37809:SF1	RIBOSOMAL PROTEIN S12 METHYLTHIOTRANSFERASE ACCESSORY FACTOR YCAO	RIBOSOMAL PROTEIN S12 METHYLTHIOTRANSFERASE ACCESSORY FACTOR YCAO	hydrolase activity#GO:0016787;nucleoside triphosphate diphosphatase activity#GO:0047429;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462		intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	chaperone#PC00072	
ECOLI|EnsemblGenome=b4068|UniProtKB=P0AF54	P0AF54	yjcH	PTHR38598:SF1	INNER MEMBRANE PROTEIN YJCH	INNER MEMBRANE PROTEIN YJCH			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b4393|UniProtKB=P0A881	P0A881	trpR	PTHR38025:SF1	TRP OPERON REPRESSOR	TRP OPERON REPRESSOR	binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565	regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468		gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;Trp repressor-like transcription factor#PC00247	
ECOLI|EnsemblGenome=b3862|UniProtKB=P32129	P32129	yihG	PTHR10983:SF15	1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED	1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE YIHG			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	acyltransferase#PC00042;transferase#PC00220	
ECOLI|EnsemblGenome=b1128|UniProtKB=P27431	P27431	roxA	PTHR13096:SF10	MINA53  MYC INDUCED NUCLEAR ANTIGEN	RIBOSOMAL PROTEIN UL16 3-HYDROXYLASE	catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;dioxygenase activity#GO:0051213				
ECOLI|EnsemblGenome=b4512|UniProtKB=P0AAS9	P0AAS9	ybdD	PTHR38453:SF3	CYTOPLASMIC PROTEIN-RELATED	CYTOPLASMIC PROTEIN					
ECOLI|EnsemblGenome=b1026|UniProtKB=P0CF82	P0CF82	insF4	PTHR42648:SF5	TRANSPOSASE, PUTATIVE-RELATED	TRANSPOSASE INSF FOR INSERTION SEQUENCE IS3A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b2550|UniProtKB=P76586	P76586	yphH	PTHR18964:SF178	ROK (REPRESSOR, ORF, KINASE) FAMILY	DNA-BINDING TRANSCRIPTIONAL REPRESSOR MLC	DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676	nucleic acid biosynthetic process#GO:0141187;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA-templated transcription#GO:0006351;gene expression#GO:0010467		winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b3833|UniProtKB=P0A887	P0A887	ubiE	PTHR43591:SF116	METHYLTRANSFERASE	2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL	transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168	biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;ubiquinone biosynthetic process#GO:0006744;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ketone metabolic process#GO:0042180;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152		methyltransferase#PC00155;transferase#PC00220	
ECOLI|EnsemblGenome=b4089|UniProtKB=P0ACS7	P0ACS7	rpiR	PTHR30514:SF1	GLUCOKINASE	HTH-TYPE TRANSCRIPTIONAL REGULATOR HEXR-RELATED	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252	protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991	kinase#PC00137	
ECOLI|EnsemblGenome=b3261|UniProtKB=P0A6R3	P0A6R3	fis	PTHR47918:SF1	DNA-BINDING PROTEIN FIS	DNA-BINDING PROTEIN FIS	DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488			helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b2146|UniProtKB=P76440	P76440	preT	PTHR11938:SF91	FAD NADPH DEHYDROGENASE/OXIDOREDUCTASE	NADPH:ADRENODOXIN OXIDOREDUCTASE, MITOCHONDRIAL	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	Vitamin D metabolism and pathway#P04396>FdxR#P04604
ECOLI|EnsemblGenome=b4359|UniProtKB=P39401	P39401	mdoB	PTHR47371:SF3	LIPOTEICHOIC ACID SYNTHASE	PHOSPHOGLYCEROL TRANSFERASE I	catalytic activity#GO:0003824;transferase activity#GO:0016740		membrane#GO:0016020;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1540|UniProtKB=P0ACM2	P0ACM2	rspR	PTHR43537:SF51	TRANSCRIPTIONAL REGULATOR, GNTR FAMILY	HTH-TYPE TRANSCRIPTIONAL REGULATOR LGOR-RELATED	DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252		helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b2304|UniProtKB=P77775	P77775	yfcH	PTHR11092:SF0	SUGAR NUCLEOTIDE EPIMERASE RELATED	EPIMERASE FAMILY PROTEIN SDR39U1				epimerase/racemase#PC00096	
ECOLI|Gene_OrderedLocusName=b4573|UniProtKB=P30192	P30192	insZ	PTHR37529:SF1	TRANSPOSASE INSG FOR INSERTION SEQUENCE ELEMENT IS4-RELATED	TRANSPOSASE INSG FOR INSERTION SEQUENCE ELEMENT IS4-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b2622|UniProtKB=P32053	P32053	intA	PTHR30629:SF6	PROPHAGE INTEGRASE	PROPHAGE INTEGRASE INTA-RELATED	catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824				
ECOLI|EnsemblGenome=b1683|UniProtKB=P77522	P77522	sufB	PTHR30508:SF1	FES CLUSTER ASSEMBLY PROTEIN SUF	IRON-SULFUR CLUSTER ASSEMBLY SUFBD FAMILY PROTEIN ABCI8, CHLOROPLASTIC-RELATED		cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;iron-sulfur cluster assembly#GO:0016226;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	chaperone#PC00072	
ECOLI|EnsemblGenome=b1421|UniProtKB=P05704	P05704	trg	PTHR43531:SF5	PROTEIN ICFG	METHYL-ACCEPTING CHEMOTAXIS PROTEIN III	molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888	locomotion#GO:0040011;response to external stimulus#GO:0009605;response to stimulus#GO:0050896;taxis#GO:0042330;response to chemical#GO:0042221;chemotaxis#GO:0006935	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b3867|UniProtKB=P32131	P32131	hemN	PTHR13932:SF6	COPROPORPHYRINIGEN III OXIDASE	OXYGEN-INDEPENDENT COPROPORPHYRINOGEN III OXIDASE	iron-sulfur cluster binding#GO:0051536;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;binding#GO:0005488;small molecule binding#GO:0036094	cellular process#GO:0009987;porphyrin-containing compound metabolic process#GO:0006778;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;biosynthetic process#GO:0009058;porphyrin-containing compound biosynthetic process#GO:0006779;tetrapyrrole biosynthetic process#GO:0033014	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	oxidase#PC00175	
ECOLI|EnsemblGenome=b3041|UniProtKB=P0A7J0	P0A7J0	ribB	PTHR21327:SF38	GTP CYCLOHYDROLASE II-RELATED	3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE	carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;lyase activity#GO:0016829	metabolic process#GO:0008152;cellular process#GO:0009987;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;flavin-containing compound metabolic process#GO:0042726	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	hydrolase#PC00121	
ECOLI|EnsemblGenome=b1728|UniProtKB=P64481	P64481	ydjM	PTHR35531:SF1	INNER MEMBRANE PROTEIN YBCI-RELATED	INNER MEMBRANE PROTEIN YBCI-RELATED			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b0819|UniProtKB=P0AAX8	P0AAX8	ybiS	PTHR30582:SF31	L,D-TRANSPEPTIDASE	L,D-TRANSPEPTIDASE YBIS-RELATED	peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;serine-type peptidase activity#GO:0008236	peptidoglycan-based cell wall biogenesis#GO:0009273;peptidoglycan metabolic process#GO:0000270;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;glycosaminoglycan biosynthetic process#GO:0006024;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;cell wall macromolecule biosynthetic process#GO:0044038;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;cell wall organization or biogenesis#GO:0071554;aminoglycan metabolic process#GO:0006022;cell wall macromolecule metabolic process#GO:0044036;cell wall biogenesis#GO:0042546;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan metabolic process#GO:0030203;peptidoglycan biosynthetic process#GO:0009252	extracellular region#GO:0005576;cellular anatomical structure#GO:0110165	cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190	
ECOLI|EnsemblGenome=b0996|UniProtKB=P33226	P33226	torC	PTHR30333:SF2	CYTOCHROME C-TYPE PROTEIN	CYTOCHROME C-TYPE PROTEIN TORC		metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;anaerobic electron transport chain#GO:0019645;anaerobic respiration#GO:0009061		primary active transporter#PC00068;transporter#PC00227	
ECOLI|EnsemblGenome=b1741|UniProtKB=P76213	P76213	cho	PTHR30562:SF10	UVRC/OXIDOREDUCTASE	EXCINUCLEASE CHO	catalytic activity, acting on DNA#GO:0140097;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536	response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554	endonuclease complex#GO:1905348;catalytic complex#GO:1902494;DNA repair complex#GO:1990391;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535	endodeoxyribonuclease#PC00093;DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b3222|UniProtKB=P45425	P45425	nanK	PTHR18964:SF169	ROK (REPRESSOR, ORF, KINASE) FAMILY	N-ACETYLMANNOSAMINE KINASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773	carboxylic acid catabolic process#GO:0046395;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino sugar catabolic process#GO:0046348		winged helix/forkhead transcription factor#PC00246	N-acetylglucosamine metabolism#P02756>N-acetylmannosamine kinase#P03038
ECOLI|EnsemblGenome=b0185|UniProtKB=P0ABD5	P0ABD5	accA	PTHR42853:SF3	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT ALPHA	ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT ALPHA, CHLOROPLASTIC				transferase#PC00220;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2110|UniProtKB=P33342	P33342	yehC	PTHR30251:SF10	PILUS ASSEMBLY CHAPERONE	FIMBRIAL CHAPERONE YEHC-RELATED		protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152	periplasmic space#GO:0042597;extracellular region#GO:0005576;cell envelope#GO:0030313;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165	chaperone#PC00072	
ECOLI|EnsemblGenome=b2429|UniProtKB=P77272	P77272	murP	PTHR30175:SF1	PHOSPHOTRANSFERASE SYSTEM TRANSPORT PROTEIN	PTS SYSTEM N-ACETYLMURAMIC ACID-SPECIFIC EIIBC COMPONENT-RELATED				secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b4355|UniProtKB=P02942	P02942	tsr	PTHR43531:SF14	PROTEIN ICFG	METHYL-ACCEPTING CHEMOTAXIS PROTEIN I-RELATED	molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888	response to external stimulus#GO:0009605;locomotion#GO:0040011;response to chemical#GO:0042221;taxis#GO:0042330;response to stimulus#GO:0050896;chemotaxis#GO:0006935	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b1159|UniProtKB=P24200	P24200	mcrA	PTHR33877:SF1	SLL1193 PROTEIN	TYPE IV METHYL-DIRECTED RESTRICTION ENZYME ECOKMCRA					
ECOLI|EnsemblGenome=b1974|UniProtKB=P76345	P76345	yodB	PTHR30529:SF3	CYTOCHROME B561	CYTOCHROME B561 HOMOLOG 1	tetrapyrrole binding#GO:0046906;heme binding#GO:0020037;binding#GO:0005488		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1806|UniProtKB=P0AA91	P0AA91	yeaY	PTHR37530:SF1	OUTER MEMBRANE PROTEIN SLP	OUTER MEMBRANE PROTEIN SLP			cellular anatomical structure#GO:0110165;membrane#GO:0016020;outer membrane#GO:0019867		
ECOLI|EnsemblGenome=b4305|UniProtKB=P39366	P39366	sgcX	PTHR32481:SF12	AMINOPEPTIDASE	AMINOPEPTIDASE SGCX-RELATED	exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235			metalloprotease#PC00153	
ECOLI|EnsemblGenome=b0878|UniProtKB=P75830	P75830	macA	PTHR30469:SF34	MULTIDRUG RESISTANCE PROTEIN MDTA	MACROLIDE EXPORT PROTEIN MACA	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;efflux transmembrane transporter activity#GO:0015562		membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b4095|UniProtKB=P16689	P16689	phnM	PTHR43135:SF3	ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE	ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE				hydrolase#PC00121;phosphatase#PC00181	
ECOLI|EnsemblGenome=b3860|UniProtKB=P0AEG4	P0AEG4	dsbA	PTHR35891:SF2	THIOL:DISULFIDE INTERCHANGE PROTEIN DSBA	THIOL:DISULFIDE INTERCHANGE PROTEIN DSBA	protein-disulfide reductase activity#GO:0015035;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;isomerase activity#GO:0016853;disulfide oxidoreductase activity#GO:0015036;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;intramolecular oxidoreductase activity#GO:0016860;protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824	cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to antibiotic#GO:0046677;response to stimulus#GO:0050896;response to chemical#GO:0042221	cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313;extracellular region#GO:0005576;periplasmic space#GO:0042597		
ECOLI|EnsemblGenome=b1252|UniProtKB=P02929	P02929	tonB	PTHR33446:SF8	PROTEIN TONB-RELATED	PROTEIN TONB	molecular transducer activity#GO:0060089		plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1505|UniProtKB=P76137	P76137	ydeT	PTHR30451:SF21	OUTER MEMBRANE USHER PROTEIN	FIMBRIAL USHER DOMAIN-CONTAINING PROTEIN YDET-RELATED	channel activity#GO:0015267;wide pore channel activity#GO:0022829;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803	cell adhesion#GO:0007155;cellular process#GO:0009987	cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane#GO:0019867;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;cell outer membrane#GO:0009279;membrane#GO:0016020		
ECOLI|EnsemblGenome=b3544|UniProtKB=P23847	P23847	dppA	PTHR30290:SF84	PERIPLASMIC BINDING COMPONENT OF ABC TRANSPORTER	D,D-DIPEPTIDE-BINDING PERIPLASMIC PROTEIN DDPA-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;transport#GO:0006810;dipeptide transport#GO:0042938;establishment of localization#GO:0051234;localization#GO:0051179;oligopeptide transport#GO:0006857	periplasmic space#GO:0042597;extracellular region#GO:0005576;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313	ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227	
ECOLI|EnsemblGenome=b4066|UniProtKB=P32704	P32704	yjcF	PTHR14136:SF17	BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9	BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9					
ECOLI|EnsemblGenome=b2930|UniProtKB=P21437	P21437	yggF	PTHR30447:SF0	FRUCTOSE-1,6-BISPHOSPHATASE CLASS 2	FRUCTOSE-1,6-BISPHOSPHATASE 1 CLASS 2-RELATED	hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;sugar-phosphatase activity#GO:0050308;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824	glucose metabolic process#GO:0006006;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;small molecule biosynthetic process#GO:0044283;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;gluconeogenesis#GO:0006094;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;hexose biosynthetic process#GO:0019319		carbohydrate phosphatase#PC00066;hydrolase#PC00121;phosphatase#PC00181	
ECOLI|EnsemblGenome=b1442|UniProtKB=P77156	P77156	ydcU	PTHR42929:SF1	INNER MEMBRANE ABC TRANSPORTER PERMEASE PROTEIN YDCU-RELATED-RELATED	INNER MEMBRANE ABC TRANSPORTER PERMEASE PROTEIN YDCU-RELATED	primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b2810|UniProtKB=Q46925	Q46925	csdA	PTHR43586:SF8	CYSTEINE DESULFURASE	CYSTEINE DESULFURASE 1, CHLOROPLASTIC	transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782			lyase#PC00144	
ECOLI|EnsemblGenome=b1755|UniProtKB=P76224	P76224	ynjC	PTHR30183:SF6	MOLYBDENUM TRANSPORT SYSTEM PERMEASE PROTEIN MODB	INNER MEMBRANE ABC TRANSPORTER PERMEASE PROTEIN YNJC	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b3094|UniProtKB=P0ACL2	P0ACL2	exuR	PTHR43537:SF7	TRANSCRIPTIONAL REGULATOR, GNTR FAMILY	EXU REGULON TRANSCRIPTIONAL REGULATOR	transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794		helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b1525|UniProtKB=P76149	P76149	sad	PTHR43217:SF1	SUCCINATE SEMIALDEHYDE DEHYDROGENASE [NAD(P)+] SAD	SUCCINATE SEMIALDEHYDE DEHYDROGENASE [NAD(P)+] SAD	oxidoreductase activity#GO:0016491;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903	cellular process#GO:0009987;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152		dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	Aminobutyrate degradation#P02726>Succinate semi-aldehyde dehydrogenase#P02824
ECOLI|EnsemblGenome=b4307|UniProtKB=P39368	P39368	yjhQ	PTHR43617:SF2	L-AMINO ACID N-ACETYLTRANSFERASE	UPF0039 PROTEIN SLL0451	catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747			acetyltransferase#PC00038	
ECOLI|EnsemblGenome=b2100|UniProtKB=P76419	P76419	yegV	PTHR43085:SF1	HEXOKINASE FAMILY MEMBER	L-GLYCERO-L-GALACTO-OCTULURONATE KINASE-RELATED	catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772			transferase#PC00220;metabolite interconversion enzyme#PC00262;carbohydrate kinase#PC00065	
ECOLI|EnsemblGenome=b0161|UniProtKB=P0C0V0	P0C0V0	degP	PTHR22939:SF129	SERINE PROTEASE FAMILY S1C HTRA-RELATED	PERIPLASMIC SERINE ENDOPROTEASE DEGP				serine protease#PC00203;protease#PC00190	
ECOLI|EnsemblGenome=b0514|UniProtKB=P77364	P77364	glxK	PTHR21599:SF0	GLYCERATE KINASE	GLYCERATE KINASE	phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740			kinase#PC00137	Allantoin degradation#P02725>Glycerate kinase II#P02817
ECOLI|EnsemblGenome=b3379|UniProtKB=P45548	P45548	php	PTHR10819:SF3	PHOSPHOTRIESTERASE-RELATED	N-ACETYLTAURINE HYDROLASE				esterase#PC00097;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1057|UniProtKB=P75925	P75925	yceJ	PTHR30529:SF1	CYTOCHROME B561	CYTOCHROME B561 HOMOLOG 2	tetrapyrrole binding#GO:0046906;binding#GO:0005488;heme binding#GO:0020037		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b0037|UniProtKB=P31552	P31552	caiC	PTHR24096:SF421	LONG-CHAIN-FATTY-ACID--COA LIGASE	CROTONOBETAINE_CARNITINE--COA LIGASE	catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874			ligase#PC00142	
ECOLI|EnsemblGenome=b3908|UniProtKB=P00448	P00448	sodA	PTHR43595:SF4	37S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL	SUPEROXIDE DISMUTASE [MN]	catalytic activity#GO:0003824;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491	cellular response to chemical stimulus#GO:0070887;cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;cellular response to stimulus#GO:0051716;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;superoxide metabolic process#GO:0006801;response to reactive oxygen species#GO:0000302;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular oxidant detoxification#GO:0098869;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	ribosomal protein#PC00202;translational protein#PC00263	
ECOLI|EnsemblGenome=b2053|UniProtKB=P0AC88	P0AC88	gmd	PTHR43715:SF1	GDP-MANNOSE 4,6-DEHYDRATASE	GDP-MANNOSE 4,6 DEHYDRATASE				dehydratase#PC00091;lyase#PC00144	Mannose metabolism#P02752>GDP-Mannose 4,6-dehydratase#P03015
ECOLI|EnsemblGenome=b1454|UniProtKB=P76117	P76117	yncG	PTHR44051:SF8	GLUTATHIONE S-TRANSFERASE-RELATED	GLUTATHIONE S-TRANSFERASE GSTA	glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765		cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	metabolite interconversion enzyme#PC00262;transferase#PC00220	
ECOLI|EnsemblGenome=b3732|UniProtKB=P0ABB4	P0ABB4	atpD	PTHR15184:SF71	ATP SYNTHASE	ATP SYNTHASE SUBUNIT BETA, CHLOROPLASTIC				ATP synthase#PC00002	
ECOLI|EnsemblGenome=b3984|UniProtKB=P0A7L0	P0A7L0	rplA	PTHR36427:SF3	54S RIBOSOMAL PROTEIN L1, MITOCHONDRIAL	LARGE RIBOSOMAL SUBUNIT PROTEIN UL1C	structural molecule activity#GO:0005198;RNA binding#GO:0003723;mRNA binding#GO:0003729;structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676	post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794		ribosomal protein#PC00202;translational protein#PC00263	
ECOLI|EnsemblGenome=b0430|UniProtKB=P0ABJ3	P0ABJ3	cyoC	PTHR11403:SF12	CYTOCHROME C OXIDASE SUBUNIT III	CYTOCHROME BO(3) UBIQUINOL OXIDASE SUBUNIT 3	monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324	aerobic respiration#GO:0009060;monoatomic ion transport#GO:0006811;localization#GO:0051179;oxidative phosphorylation#GO:0006119;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;cellular respiration#GO:0045333;aerobic electron transport chain#GO:0019646;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;transport#GO:0006810;metabolic process#GO:0008152;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900	cell periphery#GO:0071944;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495	oxidoreductase#PC00176;oxidase#PC00175	
ECOLI|EnsemblGenome=b3967|UniProtKB=P22634	P22634	murI	PTHR21198:SF2	GLUTAMATE RACEMASE	GLUTAMATE RACEMASE	catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;isomerase activity#GO:0016853	macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;cell wall macromolecule biosynthetic process#GO:0044038;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;cell wall organization or biogenesis#GO:0071554;peptidoglycan-based cell wall biogenesis#GO:0009273;peptidoglycan metabolic process#GO:0000270;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;glycosaminoglycan biosynthetic process#GO:0006024;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan metabolic process#GO:0030203;peptidoglycan biosynthetic process#GO:0009252;aminoglycan metabolic process#GO:0006022;cell wall macromolecule metabolic process#GO:0044036;cell wall biogenesis#GO:0042546			Peptidoglycan biosynthesis#P02763>Glutamate racemase#P03087
ECOLI|EnsemblGenome=b0383|UniProtKB=P00634	P00634	phoA	PTHR11596:SF99	ALKALINE PHOSPHATASE	ALKALINE PHOSPHATASE	hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787		periplasmic space#GO:0042597;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165	phosphatase#PC00181;hydrolase#PC00121	
ECOLI|EnsemblGenome=b2478|UniProtKB=P0A6L2	P0A6L2	dapA	PTHR12128:SF66	DIHYDRODIPICOLINATE SYNTHASE	4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE	lyase activity#GO:0016829;catalytic activity#GO:0003824		cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	lyase#PC00144	Lysine biosynthesis#P02751>Dihydrodipicolinate synthase#P03008
ECOLI|EnsemblGenome=b2663|UniProtKB=P25527	P25527	gabP	PTHR43495:SF5	GABA PERMEASE	GAMMA-AMINOBUTYRIC ACID PERMEASE	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;active transmembrane transporter activity#GO:0022804		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	secondary carrier transporter#PC00258;amino acid transporter#PC00046;transporter#PC00227	
ECOLI|EnsemblGenome=b2547|UniProtKB=P77509	P77509	yphE	PTHR43790:SF9	CARBOHYDRATE TRANSPORT ATP-BINDING PROTEIN MG119-RELATED	GALACTOFURANOSE TRANSPORTER ATP-BINDING PROTEIN YTFR	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b0457|UniProtKB=P77473	P77473	pdeB	PTHR33121:SF71	CYCLIC DI-GMP PHOSPHODIESTERASE PDEF	CYCLIC DI-GMP PHOSPHODIESTERASE PDEL-RELATED	phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121	
ECOLI|EnsemblGenome=b0432|UniProtKB=P0ABJ1	P0ABJ1	cyoA	PTHR22888:SF18	CYTOCHROME C OXIDASE, SUBUNIT II	CYTOCHROME BO(3) UBIQUINOL OXIDASE SUBUNIT 2	monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;electron transfer activity#GO:0009055;monoatomic cation transmembrane transporter activity#GO:0008324	cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152	respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991	oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2829|UniProtKB=P37177	P37177	ptsP	PTHR46244:SF1	PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE	PHOSPHOENOLPYRUVATE-DEPENDENT PHOSPHOTRANSFERASE SYSTEM	transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;catalytic activity#GO:0003824;transferase activity#GO:0016740	localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;carbohydrate derivative transport#GO:1901264		protein modifying enzyme#PC00260	
ECOLI|EnsemblGenome=b0331|UniProtKB=P77541	P77541	prpB	PTHR42905:SF17	PHOSPHOENOLPYRUVATE CARBOXYLASE	2-METHYLISOCITRATE LYASE	catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829	metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;short-chain fatty acid catabolic process#GO:0019626;fatty acid catabolic process#GO:0009062;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282		mutase#PC00160	Methylcitrate cycle#P02754>2-methylisocitrate lyase#P03027
ECOLI|EnsemblGenome=b2414|UniProtKB=P0ABK5	P0ABK5	cysK	PTHR10314:SF260	CYSTATHIONINE BETA-SYNTHASE	CYSTEINE SYNTHASE A	lyase activity#GO:0016829;carbon-sulfur lyase activity#GO:0016846;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740	amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	metabolite interconversion enzyme#PC00262;lyase#PC00144	Cysteine biosynthesis#P02737>O-Acetylserine-lyase#P02887
ECOLI|EnsemblGenome=b1327|UniProtKB=P76049	P76049	ycjY	PTHR47751:SF1	SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G16580)-RELATED	SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G16580)-RELATED				hydrolase#PC00121	
ECOLI|EnsemblGenome=b0397|UniProtKB=P13458	P13458	sbcC	PTHR32114:SF2	ABC TRANSPORTER ABCH.3	RAD50_SBCC-TYPE AAA DOMAIN-CONTAINING PROTEIN	catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;DNA exonuclease activity#GO:0004529;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;exonuclease activity#GO:0004527	cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170	catalytic complex#GO:1902494;DNA repair complex#GO:1990391;protein-containing complex#GO:0032991	ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227	
ECOLI|EnsemblGenome=b4130|UniProtKB=P39276	P39276	dtpC	PTHR11654:SF462	OLIGOPEPTIDE TRANSPORTER-RELATED	DIPEPTIDE AND TRIPEPTIDE PERMEASE C	proton transmembrane transporter activity#GO:0015078;oligopeptide transmembrane transporter activity#GO:0035673;dipeptide transmembrane transporter activity#GO:0071916;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;tripeptide transmembrane transporter activity#GO:0042937;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;solute:proton symporter activity#GO:0015295;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324	transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;dipeptide transport#GO:0042938;transmembrane transport#GO:0055085;oligopeptide transport#GO:0006857;peptide transport#GO:0015833;nitrogen compound transport#GO:0071705;oligopeptide transmembrane transport#GO:0035672;cellular process#GO:0009987	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b1531|UniProtKB=P0ACH5	P0ACH5	marA	PTHR47504:SF4	RIGHT ORIGIN-BINDING PROTEIN	MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN MARA	binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;protein binding#GO:0005515;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b2528|UniProtKB=P0AAC8	P0AAC8	iscA	PTHR10072:SF66	IRON-SULFUR CLUSTER ASSEMBLY PROTEIN	IRON-BINDING PROTEIN ISCA	iron-sulfur cluster binding#GO:0051536;binding#GO:0005488;small molecule binding#GO:0036094	biosynthetic process#GO:0009058;iron-sulfur cluster assembly#GO:0016226;protein maturation#GO:0051604;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	chaperone#PC00072	
ECOLI|Gene_OrderedLocusName=JW5811|UniProtKB=Q47153	Q47153	lfhA	PTHR30161:SF1	FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED	FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED		cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;bacterial-type flagellum assembly#GO:0044780	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b3279|UniProtKB=P0A9W9	P0A9W9	yrdA	PTHR13061:SF56	DYNACTIN SUBUNIT P25	PROTEIN YRDA				microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156	
ECOLI|EnsemblGenome=b0526|UniProtKB=P21888	P21888	cysS	PTHR10890:SF34	CYSTEINYL-TRNA SYNTHETASE	CYSTEINE--TRNA LIGASE	catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098	protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047	
ECOLI|EnsemblGenome=b2160|UniProtKB=P33020	P33020	yeiI	PTHR43085:SF1	HEXOKINASE FAMILY MEMBER	L-GLYCERO-L-GALACTO-OCTULURONATE KINASE-RELATED	transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301			transferase#PC00220;metabolite interconversion enzyme#PC00262;carbohydrate kinase#PC00065	
ECOLI|EnsemblGenome=b2638|UniProtKB=P0CF86	P0CF86	yfjU	PTHR30041:SF5	ARSENATE REDUCTASE	ARSENATE REDUCTASE-RELATED		response to chemical#GO:0042221;response to stimulus#GO:0050896		reductase#PC00198	
ECOLI|EnsemblGenome=b0983|UniProtKB=P0A932	P0A932	gfcE	PTHR33619:SF3	POLYSACCHARIDE EXPORT PROTEIN GFCE-RELATED	POLYSACCHARIDE EXPORT PROTEIN GFCE-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144				
ECOLI|EnsemblGenome=b1482|UniProtKB=P0C0L2	P0C0L2	osmC	PTHR42830:SF1	OSMOTICALLY INDUCIBLE FAMILY PROTEIN	PEROXIREDOXIN OSMC	peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684		cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b3089|UniProtKB=P0AGE4	P0AGE4	sstT	PTHR42865:SF8	PROTON/GLUTAMATE-ASPARTATE SYMPORTER	SERINE_THREONINE TRANSPORTER SSTT	secondary active transmembrane transporter activity#GO:0015291;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370	nitrogen compound transport#GO:0071705;localization#GO:0051179;neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	primary active transporter#PC00068	
ECOLI|EnsemblGenome=b4214|UniProtKB=P22255	P22255	cysQ	PTHR43028:SF12	3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1	3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE CYSQ	hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788	nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	hydrolase#PC00121;phosphatase#PC00181	
ECOLI|EnsemblGenome=b4478|UniProtKB=Q6BF17	Q6BF17	dgoD	PTHR48080:SF2	D-GALACTONATE DEHYDRATASE-RELATED	D-GALACTONATE DEHYDRATASE	hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056		dehydratase#PC00091	
ECOLI|EnsemblGenome=b3569|UniProtKB=P0ACI3	P0ACI3	xylR	PTHR30146:SF24	LACI-RELATED TRANSCRIPTIONAL REPRESSOR	XYLOSE OPERON REGULATORY PROTEIN	sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789		Lambda repressor-like transcription factor#PC00245;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b0904|UniProtKB=P0AC23	P0AC23	focA	PTHR30520:SF10	FORMATE TRANSPORTER-RELATED	FORMATE CHANNEL FOCA-RELATED	carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monocarboxylic acid transmembrane transporter activity#GO:0008028;nitrate transmembrane transporter activity#GO:0015112;active transmembrane transporter activity#GO:0022804	carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;monocarboxylic acid transport#GO:0015718;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;localization#GO:0051179;nitrogen compound transport#GO:0071705	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b0450|UniProtKB=P0AC55	P0AC55	glnK	PTHR30115:SF20	NITROGEN REGULATORY PROTEIN P-II	NITROGEN REGULATORY PROTEIN GLNK	ATP binding#GO:0005524;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;enzyme regulator activity#GO:0030234;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;molecular function regulator activity#GO:0098772;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363	biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	protein-binding activity modulator#PC00095	
ECOLI|EnsemblGenome=b0494|UniProtKB=P0ADA1	P0ADA1	tesA	PTHR30383:SF24	THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1	THIOESTERASE 1_PROTEASE 1_LYSOPHOSPHOLIPASE L1	phosphatidylcholine lysophospholipase A1 activity#GO:0004622;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788	primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042;catabolic process#GO:0009056	extracellular region#GO:0005576;periplasmic space#GO:0042597;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313	metabolite interconversion enzyme#PC00262;hydrolase#PC00121	
ECOLI|EnsemblGenome=b3736|UniProtKB=P0ABA0	P0ABA0	atpF	PTHR33445:SF1	ATP SYNTHASE SUBUNIT B', CHLOROPLASTIC	ATP SYNTHASE SUBUNIT B	primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626		transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting ATP synthase complex#GO:0045259;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;membrane protein complex#GO:0098796;membrane#GO:0016020;respiratory chain complex#GO:0098803	ATP synthase#PC00002;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b3095|UniProtKB=P0AA63	P0AA63	yqjA	PTHR30353:SF11	INNER MEMBRANE PROTEIN DEDA-RELATED	INNER MEMBRANE PROTEIN YQJA	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	transport#GO:0006810;FtsZ-dependent cytokinesis#GO:0043093;cytokinesis#GO:0000910;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cell cycle process#GO:0022402;cell division#GO:0051301;cellular process#GO:0009987;cell cycle#GO:0007049;reproductive process#GO:0022414;reproductive process in single-celled organism#GO:0022413	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b4392|UniProtKB=P0AGC3	P0AGC3	slt	PTHR37423:SF5	SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE-RELATED	SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE					
ECOLI|EnsemblGenome=b3299|UniProtKB=P0A7Q6	P0A7Q6	rpmJ1	PTHR42888:SF1	50S RIBOSOMAL PROTEIN L36, CHLOROPLASTIC	LARGE RIBOSOMAL SUBUNIT PROTEIN BL36A		protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238	cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622	ribosomal protein#PC00202;translational protein#PC00263	
ECOLI|EnsemblGenome=b3744|UniProtKB=P00963	P00963	asnA	PTHR30073:SF5	ASPARTATE--AMMONIA LIGASE	ASPARTATE--AMMONIA LIGASE	catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879		cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;ligase#PC00142	
ECOLI|EnsemblGenome=b0710|UniProtKB=P0AFP6	P0AFP6	ybgI	PTHR13799:SF14	NGG1 INTERACTING FACTOR 3	NIF3-LIKE METAL-BINDING PROTEIN YBGI			cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b0862|UniProtKB=P0AE34	P0AE34	artQ	PTHR30133:SF2	CATIONIC AMINO ACID TRANSPORTER, MEMBRANE COMPONENT	ARGININE ABC TRANSPORTER PERMEASE PROTEIN ARTQ			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	amino acid transporter#PC00046;secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b0639|UniProtKB=P0A752	P0A752	nadD	PTHR12039:SF0	NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE	NICOTINAMIDE-NUCLEOTIDE ADENYLYLTRANSFERASE	nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772	nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;pyridine-containing compound metabolic process#GO:0072524;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521		nucleotidyltransferase#PC00174;transferase#PC00220	
ECOLI|EnsemblGenome=b2666|UniProtKB=P0AE42	P0AE42	yqaE	PTHR21659:SF42	HYDROPHOBIC PROTEIN RCI2  LOW TEMPERATURE AND SALT RESPONSIVE PROTEIN LTI6 -RELATED	PMP3 FAMILY PROTEIN T23F2.3-RELATED					
ECOLI|EnsemblGenome=b2901|UniProtKB=Q46829	Q46829	bglA	PTHR10353:SF349	GLYCOSYL HYDROLASE	6-PHOSPHO-BETA-GLUCOSIDASE ASCB-RELATED	hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;glucosidase activity#GO:0015926;beta-glucosidase activity#GO:0008422;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553	metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;carbohydrate catabolic process#GO:0016052;carbohydrate metabolic process#GO:0005975	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;hydrolase#PC00121;glycosidase#PC00110	
ECOLI|EnsemblGenome=b0462|UniProtKB=P31224	P31224	acrB	PTHR32063:SF13	SWARMING MOTILITY PROTEIN SWRC-RELATED	MULTIDRUG EFFLUX PUMP SUBUNIT ACRB-RELATED					
ECOLI|EnsemblGenome=b3237|UniProtKB=P0A6D0	P0A6D0	argR	PTHR34471:SF1	ARGININE REPRESSOR	ARGININE REPRESSOR	transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837		protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667	winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b2161|UniProtKB=P33021	P33021	nupX	PTHR10590:SF4	SODIUM/NUCLEOSIDE COTRANSPORTER	NUCLEOSIDE PERMEASE NUPX-RELATED	nucleobase-containing compound transmembrane transporter activity#GO:0015932;carbohydrate derivative transmembrane transporter activity#GO:1901505;symporter activity#GO:0015293;nucleoside transmembrane transporter activity#GO:0005337;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b1656|UniProtKB=P0AGD3	P0AGD3	sodB	PTHR42769:SF3	SUPEROXIDE DISMUTASE	SUPEROXIDE DISMUTASE [FE]	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;antioxidant activity#GO:0016209			metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3344|UniProtKB=P45531	P45531	tusC	PTHR38780:SF1	PROTEIN TUSC	PROTEIN TUSC		RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA thio-modification#GO:0034227;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;tRNA wobble position uridine thiolation#GO:0002143;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467	intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;sulfurtransferase complex#GO:1990228;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b2369|UniProtKB=P0ACZ4	P0ACZ4	evgA	PTHR44688:SF16	DNA-BINDING TRANSCRIPTIONAL ACTIVATOR DEVR_DOSR	DNA-BINDING TRANSCRIPTIONAL ACTIVATOR EVGA				gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b3375|UniProtKB=P45544	P45544	frlR	PTHR44846:SF18	MANNOSYL-D-GLYCERATE TRANSPORT/METABOLISM SYSTEM REPRESSOR MNGR-RELATED	FRUCTOSELYSINE UTILIZATION OPERON TRANSCRIPTIONAL REPRESSOR-RELATED		regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141		helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b1613|UniProtKB=P00946	P00946	manA	PTHR10309:SF0	MANNOSE-6-PHOSPHATE ISOMERASE	MANNOSE-6-PHOSPHATE ISOMERASE	catalytic activity#GO:0003824;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853	organophosphate biosynthetic process#GO:0090407;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleotide-sugar metabolic process#GO:0009225;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;isomerase#PC00135	Mannose metabolism#P02752>Mannose 6-P isomerase#P03017
ECOLI|EnsemblGenome=b1674|UniProtKB=P0AAL6	P0AAL6	ydhY	PTHR42859:SF17	OXIDOREDUCTASE	ELECTRON TRANSPORT PROTEIN HYDN-RELATED				metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2346|UniProtKB=P76506	P76506	mlaA	PTHR30035:SF3	LIPOPROTEIN VACJ-RELATED	INTERMEMBRANE PHOSPHOLIPID TRANSPORT SYSTEM LIPOPROTEIN MLAA		transport#GO:0006810;lipid localization#GO:0010876;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;macromolecule localization#GO:0033036;intermembrane phospholipid transfer#GO:0120010;membrane organization#GO:0061024;phospholipid transport#GO:0015914;lipid transport#GO:0006869;organophosphate ester transport#GO:0015748			
ECOLI|EnsemblGenome=b2025|UniProtKB=P60664	P60664	hisF	PTHR21235:SF2	IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISF/H  IGP SYNTHASE SUBUNIT HISF/H	IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE HISHF	pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757			lyase#PC00144;metabolite interconversion enzyme#PC00262	Histidine biosynthesis#P02747>Imidazol glycerol phosphate synthase#P02992
ECOLI|EnsemblGenome=b1430|UniProtKB=P25397	P25397	tehB	PTHR43464:SF97	METHYLTRANSFERASE	TELLURITE METHYLTRANSFERASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741			methyltransferase#PC00155;transferase#PC00220	
ECOLI|EnsemblGenome=b2571|UniProtKB=P0AFX9	P0AFX9	rseB	PTHR38782:SF1	SIGMA-E FACTOR REGULATORY PROTEIN RSEB	SIGMA-E FACTOR REGULATORY PROTEIN RSEB	binding#GO:0005488;protein binding#GO:0005515	regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of polysaccharide metabolic process#GO:0032881;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of carbohydrate metabolic process#GO:0006109;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885	cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;extracellular region#GO:0005576;periplasmic space#GO:0042597		
ECOLI|EnsemblGenome=b0676|UniProtKB=P0AF20	P0AF20	nagC	PTHR18964:SF175	ROK (REPRESSOR, ORF, KINASE) FAMILY	DNA-BINDING TRANSCRIPTIONAL DUAL REGULATOR NAGC	DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255		winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b0002|UniProtKB=P00561	P00561	thrA	PTHR43070:SF13	FAMILY NOT NAMED	BIFUNCTIONAL ASPARTOKINASE_HOMOSERINE DEHYDROGENASE 1	kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987			
ECOLI|EnsemblGenome=b2822|UniProtKB=P07648	P07648	recC	PTHR30591:SF1	RECBCD ENZYME SUBUNIT RECC	RECBCD ENZYME SUBUNIT RECC		macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304		exodeoxyribonuclease#PC00098	
ECOLI|EnsemblGenome=b0154|UniProtKB=P23893	P23893	hemL	PTHR43713:SF8	GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE	GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE	anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;intramolecular transferase activity#GO:0016866;ion binding#GO:0043167;catalytic activity#GO:0003824;isomerase activity#GO:0016853;heterocyclic compound binding#GO:1901363			mutase#PC00160	Heme biosynthesis#P02746>Glutamate-1-semialdehyde aminotransferase#P02981
ECOLI|EnsemblGenome=b0479|UniProtKB=P52067	P52067	fsr	PTHR43129:SF1	FOSMIDOMYCIN RESISTANCE PROTEIN	FOSMIDOMYCIN RESISTANCE PROTEIN			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b0809|UniProtKB=P10346	P10346	glnQ	PTHR43166:SF14	AMINO ACID IMPORT ATP-BINDING PROTEIN	GLUTAMINE TRANSPORT ATP-BINDING PROTEIN GLNQ	ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b2714|UniProtKB=P24242	P24242	ascG	PTHR30146:SF67	LACI-RELATED TRANSCRIPTIONAL REPRESSOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR ASCG	transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889		Lambda repressor-like transcription factor#PC00245;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b4243|UniProtKB=P0AF93	P0AF93	ridA	PTHR11803:SF58	2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA	2-IMINOBUTANOATE_2-IMINOPROPANOATE DEAMINASE-RELATED	catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;deaminase activity#GO:0019239		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	hydrolase#PC00121;deaminase#PC00088;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0775|UniProtKB=P12996	P12996	bioB	PTHR22976:SF2	BIOTIN SYNTHASE	BIOTIN SYNTHASE, MITOCHONDRIAL	small molecule binding#GO:0036094;transferase activity#GO:0016740;catalytic activity#GO:0003824;binding#GO:0005488;sulfurtransferase activity#GO:0016783;iron-sulfur cluster binding#GO:0051536;transferase activity, transferring sulphur-containing groups#GO:0016782	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;monocarboxylic acid metabolic process#GO:0032787;sulfur compound metabolic process#GO:0006790;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;biotin metabolic process#GO:0006768;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058		transferase#PC00220;metabolite interconversion enzyme#PC00262	Biotin biosynthesis#P02731>Biotin synthase#P02857
ECOLI|EnsemblGenome=b0155|UniProtKB=P37019	P37019	clcA	PTHR45711:SF11	CHLORIDE CHANNEL PROTEIN	H(+)_CL(-) EXCHANGE TRANSPORTER CLCA	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;chloride transmembrane transporter activity#GO:0015108;monoatomic ion transmembrane transporter activity#GO:0015075	monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transport#GO:0006810;chloride transport#GO:0006821	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227;ion channel#PC00133	
ECOLI|EnsemblGenome=b0656|UniProtKB=P0CE51	P0CE51	insH3	PTHR35604:SF2	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824	nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b3727|UniProtKB=P0AGH8	P0AGH8	pstC	PTHR30425:SF1	PHOSPHATE TRANSPORT SYSTEM PERMEASE PROTEIN PST	PHOSPHATE TRANSPORT SYSTEM PERMEASE PROTEIN PSTC		establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;phosphate ion transport#GO:0006817;inorganic anion transport#GO:0015698;transport#GO:0006810;cellular process#GO:0009987	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b0094|UniProtKB=P0ABH0	P0ABH0	ftsA	PTHR32432:SF4	CELL DIVISION PROTEIN FTSA-RELATED	CELL DIVISION PROTEIN FTSA	molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495	cell division#GO:0051301;cellular process#GO:0009987	side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell division site#GO:0032153;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b2065|UniProtKB=P28248	P28248	dcd	PTHR42680:SF3	DCTP DEAMINASE	DCTP DEAMINASE	catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814	nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;organophosphate metabolic process#GO:0019637;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238		metabolite interconversion enzyme#PC00262;deaminase#PC00088	De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCTP deaminase#P02920
ECOLI|EnsemblGenome=b4529|UniProtKB=P0ACW2	P0ACW2	ydbJ	PTHR38008:SF1	HEMOLYSIN-RELATED	LIPOPROTEIN					
ECOLI|EnsemblGenome=b3982|UniProtKB=P0AFG0	P0AFG0	nusG	PTHR30265:SF2	RHO-INTERACTING TRANSCRIPTION TERMINATION FACTOR NUSG	TRANSCRIPTION TERMINATION_ANTITERMINATION PROTEIN NUSG	transcription regulator activity#GO:0140110	positive regulation of biosynthetic process#GO:0009891;negative regulation of protein-containing complex disassembly#GO:0043242;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular component organization#GO:0051129;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of cellular component organization#GO:0051128;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of biological process#GO:0048518	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b3176|UniProtKB=P31120	P31120	glmM	PTHR42946:SF8	PHOSPHOHEXOSE MUTASE	PHOSPHOGLUCOSAMINE MUTASE	intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;intramolecular phosphotransferase activity#GO:0016868;isomerase activity#GO:0016853	phosphorus metabolic process#GO:0006793;peptidoglycan biosynthetic process#GO:0009252;small molecule metabolic process#GO:0044281;aminoglycan metabolic process#GO:0006022;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell wall organization or biogenesis#GO:0071554;metabolic process#GO:0008152;peptidoglycan metabolic process#GO:0000270;nucleobase-containing compound biosynthetic process#GO:0034654;peptidoglycan-based cell wall biogenesis#GO:0009273;nucleobase-containing small molecule metabolic process#GO:0055086;cellular component organization or biogenesis#GO:0071840;glycosaminoglycan biosynthetic process#GO:0006024;carbohydrate derivative biosynthetic process#GO:1901137;primary metabolic process#GO:0044238;glycosaminoglycan metabolic process#GO:0030203;aminoglycan biosynthetic process#GO:0006023;nucleoside phosphate metabolic process#GO:0006753;amino sugar metabolic process#GO:0006040;UDP-N-acetylglucosamine biosynthetic process#GO:0006048;cell wall macromolecule metabolic process#GO:0044036;cell wall biogenesis#GO:0042546;UDP-N-acetylglucosamine metabolic process#GO:0006047;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;organophosphate metabolic process#GO:0019637;cell wall macromolecule biosynthetic process#GO:0044038;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;macromolecule metabolic process#GO:0043170;nucleoside phosphate biosynthetic process#GO:1901293	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	mutase#PC00160;isomerase#PC00135	O-antigen biosynthesis#P02757>Phosphoglucosamine mutase#P03044;N-acetylglucosamine metabolism#P02756>Phosphoglucosamine mutase#P03035
ECOLI|EnsemblGenome=b1596|UniProtKB=P43531	P43531	ynfM	PTHR43271:SF1	BLL2771 PROTEIN	INNER MEMBRANE TRANSPORT PROTEIN YNFM				transporter#PC00227	
ECOLI|EnsemblGenome=b2720|UniProtKB=P16432	P16432	hycF	PTHR10849:SF35	NADH DEHYDROGENASE  UBIQUINONE  IRON-SULFUR PROTEIN 8, MITOCHONDRIAL	FORMATE HYDROGENLYASE SUBUNIT 6-RELATED	oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;NADH dehydrogenase activity#GO:0003954;catalytic activity#GO:0003824	metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060		metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0730|UniProtKB=P13669	P13669	mngR	PTHR44846:SF1	MANNOSYL-D-GLYCERATE TRANSPORT/METABOLISM SYSTEM REPRESSOR MNGR-RELATED	HTH-TYPE TRANSCRIPTIONAL REGULATOR GGAR-RELATED		negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355		winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b3042|UniProtKB=Q46868	Q46868	ubiK	PTHR38040:SF1	UBIQUINONE BIOSYNTHESIS ACCESSORY FACTOR UBIK	UBIQUINONE BIOSYNTHESIS ACCESSORY FACTOR UBIK					
ECOLI|EnsemblGenome=b3323|UniProtKB=P45756	P45756	gspA	PTHR35894:SF1	GENERAL SECRETION PATHWAY PROTEIN A-RELATED	GENERAL SECRETION PATHWAY PROTEIN A-RELATED					
ECOLI|EnsemblGenome=b3902|UniProtKB=P32169	P32169	rhaD	PTHR22789:SF16	FUCULOSE PHOSPHATE ALDOLASE	RHAMNULOSE-1-PHOSPHATE ALDOLASE	catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832	carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996		lyase#PC00144;aldolase#PC00044	
ECOLI|EnsemblGenome=b3778|UniProtKB=P09980	P09980	rep	PTHR11070:SF64	UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER	ATP-DEPENDENT DNA HELICASE REP	ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097	macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA recombination#GO:0006310;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b2257|UniProtKB=P76473	P76473	arnT	PTHR33908:SF12	MANNOSYLTRANSFERASE YKCB-RELATED	UNDECAPRENYL PHOSPHATE-ALPHA-4-AMINO-4-DEOXY-L-ARABINOSE ARABINOSYL TRANSFERASE	glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763	lipid metabolic process#GO:0006629;response to metal ion#GO:0010038;metabolic process#GO:0008152;response to iron ion#GO:0010039;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;response to chemical#GO:0042221;polysaccharide biosynthetic process#GO:0000271;lipopolysaccharide metabolic process#GO:0008653;primary metabolic process#GO:0044238;lipopolysaccharide biosynthetic process#GO:0009103;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;response to stimulus#GO:0050896;liposaccharide metabolic process#GO:1903509	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;transferase#PC00220	
ECOLI|EnsemblGenome=b3888|UniProtKB=P0ADQ2	P0ADQ2	fabY	PTHR43072:SF8	N-ACETYLTRANSFERASE	ACYLTRANSFERASE FABY-RELATED	acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824			acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1011|UniProtKB=P75897	P75897	rutB	PTHR43540:SF6	PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED	ISOCHORISMATASE-LIKE DOMAIN-CONTAINING PROTEIN				hydrolase#PC00121	
ECOLI|EnsemblGenome=b1441|UniProtKB=P77795	P77795	ydcT	PTHR42781:SF10	SPERMIDINE/PUTRESCINE IMPORT ATP-BINDING PROTEIN POTA	SPERMIDINE_PUTRESCINE IMPORT ATP-BINDING PROTEIN POTA	transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;polyamine transmembrane transporter activity#GO:0015203		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227	
ECOLI|EnsemblGenome=b4349|UniProtKB=P08957	P08957	hsdM	PTHR42933:SF4	SLR6095 PROTEIN	TYPE I RESTRICTION ENZYME ECOKI METHYLASE SUBUNIT	catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170	cellular process#GO:0009987;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;nucleobase-containing compound metabolic process#GO:0006139;defense response to other organism#GO:0098542;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;defense response#GO:0006952;response to external stimulus#GO:0009605;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;macromolecule modification#GO:0043412			
ECOLI|EnsemblGenome=b3636|UniProtKB=P0A7N9	P0A7N9	rpmG	PTHR15238:SF2	54S RIBOSOMAL PROTEIN L39, MITOCHONDRIAL	LARGE RIBOSOMAL SUBUNIT PROTEIN BL33	structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735		intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165	ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b4301|UniProtKB=P39362	P39362	sgcE	PTHR11749:SF5	RIBULOSE-5-PHOSPHATE-3-EPIMERASE	EPIMERASE SGCE-RELATED	D-ribulose-phosphate 3-epimerase activity#GO:0004750;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853	purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt, non-oxidative branch#GO:0009052;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;NADPH regeneration#GO:0006740;glyceraldehyde-3-phosphate metabolic process#GO:0019682;pyridine-containing compound metabolic process#GO:0072524;pentose-phosphate shunt#GO:0006098;nucleotide metabolic process#GO:0009117;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829		Ascorbate degradation#P02729>L-xylulose-5-phosphate-3-epimerase#P02852
ECOLI|EnsemblGenome=b2299|UniProtKB=P65556	P65556	yfcD	PTHR43758:SF6	7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE	NUDIX HYDROLASE 3	hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity#GO:0016787		cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	phosphatase#PC00181;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1493|UniProtKB=P69910	P69910	gadB	PTHR43321:SF3	GLUTAMATE DECARBOXYLASE	GLUTAMATE DECARBOXYLASE	carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	decarboxylase#PC00089;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2690|UniProtKB=P77475	P77475	yqaB	PTHR43481:SF4	FRUCTOSE-1-PHOSPHATE PHOSPHATASE	FRUCTOSE-1-PHOSPHATE PHOSPHATASE YQAB	catalytic activity#GO:0003824;sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578	cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975		hydrolase#PC00121;carbohydrate phosphatase#PC00066	
ECOLI|EnsemblGenome=b1733|UniProtKB=P37794	P37794	chbG	PTHR31609:SF2	YDJC DEACETYLASE FAMILY MEMBER	CHITOOLIGOSACCHARIDE DEACETYLASE CHBG	deacetylase activity#GO:0019213;deacylase activity#GO:0160215;catalytic activity#GO:0003824	cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;metabolic process#GO:0008152;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056			
ECOLI|EnsemblGenome=b0232|UniProtKB=Q47156	Q47156	yafN	PTHR33713:SF10	ANTITOXIN YAFN-RELATED	ANTITOXIN YAFN	transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677	regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255			
ECOLI|EnsemblGenome=b0078|UniProtKB=P00894	P00894	ilvH	PTHR30239:SF0	ACETOLACTATE SYNTHASE SMALL SUBUNIT	ACETOLACTATE SYNTHASE SMALL SUBUNIT 1, CHLOROPLASTIC	transketolase or transaldolase activity#GO:0016744;catalytic activity#GO:0003824;transferase activity#GO:0016740	proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;branched-chain amino acid biosynthetic process#GO:0009082;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	transferase#PC00220	
ECOLI|EnsemblGenome=b1183|UniProtKB=P0AG11	P0AG11	umuD	PTHR33516:SF2	LEXA REPRESSOR	LEXA REPRESSOR-RELATED	binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;DNA-binding transcription repressor activity#GO:0001217;sequence-specific DNA binding#GO:0043565	cellular response to stress#GO:0033554;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;SOS response#GO:0009432;negative regulation of macromolecule metabolic process#GO:0010605;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219	protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993	helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218;Lambda repressor-like transcription factor#PC00245	
ECOLI|EnsemblGenome=b0529|UniProtKB=P24186	P24186	folD	PTHR48099:SF33	C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED	BIFUNCTIONAL PROTEIN FOLD	hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;oxidoreductase activity#GO:0016491;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824	cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152;tetrahydrofolate metabolic process#GO:0046653	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262	Formyltetrahydrofolate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952
ECOLI|EnsemblGenome=b2270|UniProtKB=P76481	P76481	yfbK	PTHR10166:SF70	VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED	VWFA DOMAIN-CONTAINING PROTEIN				voltage-gated ion channel#PC00241;transporter#PC00227	
ECOLI|EnsemblGenome=b4358|UniProtKB=P39400	P39400	lgoD	PTHR43401:SF3	L-THREONINE 3-DEHYDROGENASE	L-GALACTONATE-5-DEHYDROGENASE	catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614	primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0048|UniProtKB=P0ABQ4	P0ABQ4	folA	PTHR48069:SF7	DIHYDROFOLATE REDUCTASE	DIHYDROFOLATE REDUCTASE	nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;binding#GO:0005488;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;purine nucleotide binding#GO:0017076	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;tetrahydrofolate biosynthetic process#GO:0046654;tetrahydrofolate metabolic process#GO:0046653;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;biosynthetic process#GO:0009058		reductase#PC00198;oxidoreductase#PC00176	Tetrahydrofolate biosynthesis#P02742>Dihydrofolate reductase#P02948;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943;Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate reductase#P02957
ECOLI|EnsemblGenome=b1599|UniProtKB=P69210	P69210	mdtI	PTHR30561:SF6	SMR FAMILY PROTON-DEPENDENT DRUG EFFLUX TRANSPORTER SUGE	SPERMIDINE EXPORT PROTEIN MDTI	active transmembrane transporter activity#GO:0022804;polyamine transmembrane transporter activity#GO:0015203;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297	nitrogen compound transport#GO:0071705;quaternary ammonium group transport#GO:0015697;cellular process#GO:0009987;xenobiotic detoxification by transmembrane export across the plasma membrane#GO:1990961;response to toxic substance#GO:0009636;response to chemical#GO:0042221;response to stimulus#GO:0050896;export from cell#GO:0140352;detoxification#GO:0098754;xenobiotic transport#GO:0042908;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b0160|UniProtKB=P15723	P15723	dgt	PTHR11373:SF32	DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE	DEOXYGUANOSINETRIPHOSPHATE TRIPHOSPHOHYDROLASE	catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787	primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleotide metabolic process#GO:0006163;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;purine nucleotide catabolic process#GO:0006195;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086		hydrolase#PC00121	
ECOLI|EnsemblGenome=b3831|UniProtKB=P12758	P12758	udp	PTHR43691:SF11	URIDINE PHOSPHORYLASE	FI09636P-RELATED			intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172	Salvage pyrimidine ribonucleotides#P02775>Uridine phosphorylase#P03152
ECOLI|EnsemblGenome=b3946|UniProtKB=P32669	P32669	fsaB	PTHR10683:SF40	TRANSALDOLASE	FRUCTOSE-6-PHOSPHATE ALDOLASE 1-RELATED				metabolite interconversion enzyme#PC00262;aldolase#PC00044;lyase#PC00144	Pentose phosphate pathway#P02762>Transaldolase#P03081
ECOLI|EnsemblGenome=b2336|UniProtKB=P77599	P77599	yfcS	PTHR30251:SF6	PILUS ASSEMBLY CHAPERONE	FIMBRIAL CHAPERONE YFCS-RELATED		macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538	extracellular region#GO:0005576;periplasmic space#GO:0042597;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313	chaperone#PC00072	
ECOLI|EnsemblGenome=b0606|UniProtKB=P35340	P35340	ahpF	PTHR48105:SF6	THIOREDOXIN REDUCTASE 1-RELATED-RELATED	ALKYL HYDROPEROXIDE REDUCTASE SUBUNIT F	antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;disulfide oxidoreductase activity#GO:0015036	cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	oxidoreductase#PC00176;reductase#PC00198	
ECOLI|EnsemblGenome=b3265|UniProtKB=P24180	P24180	acrE	PTHR30158:SF21	ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER	MULTIDRUG EXPORT PROTEIN ACRE		establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;response to antibiotic#GO:0046677;xenobiotic transport#GO:0042908;detoxification#GO:0098754;response to toxic substance#GO:0009636;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular process#GO:0009987	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b1748|UniProtKB=P77581	P77581	astC	PTHR11986:SF123	AMINOTRANSFERASE CLASS III	SUCCINYLORNITHINE TRANSAMINASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483	carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;L-arginine biosynthetic process#GO:0006526;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;proteinogenic amino acid biosynthetic process#GO:0170038	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	transaminase#PC00216	Lysine biosynthesis#P02751>N-succinyldiaminopimelate  aminotransferase#P03011;Arginine biosynthesis#P02728>N-acetylornithine aminotransferase#P02842
ECOLI|EnsemblGenome=b4182|UniProtKB=P0AF78	P0AF78	yjfJ	PTHR31088:SF9	MEMBRANE-ASSOCIATED PROTEIN VIPP1, CHLOROPLASTIC	PSPA_IM30 FAMILY PROTEIN					
ECOLI|EnsemblGenome=b2174|UniProtKB=P76445	P76445	lpxT	PTHR14969:SF53	SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE	LIPID A 1-DIPHOSPHATE SYNTHASE				phosphatase#PC00181;hydrolase#PC00121	
ECOLI|EnsemblGenome=b3724|UniProtKB=P0A9K7	P0A9K7	phoU	PTHR42930:SF3	PHOSPHATE-SPECIFIC TRANSPORT SYSTEM ACCESSORY PROTEIN PHOU	PHOSPHATE-SPECIFIC TRANSPORT SYSTEM ACCESSORY PROTEIN PHOU		negative regulation of cellular process#GO:0048523;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;regulation of transmembrane transport#GO:0034762;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	protein-binding activity modulator#PC00095	
ECOLI|EnsemblGenome=b2488|UniProtKB=P77423	P77423	hyfH	PTHR10849:SF35	NADH DEHYDROGENASE  UBIQUINONE  IRON-SULFUR PROTEIN 8, MITOCHONDRIAL	FORMATE HYDROGENLYASE SUBUNIT 6-RELATED	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;NADH dehydrogenase activity#GO:0003954	energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091		metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0470|UniProtKB=P06710	P06710	dnaX	PTHR11669:SF0	REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT	PROTEIN STICHEL-LIKE 3		nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;DNA replication#GO:0006260;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;metabolic process#GO:0008152;DNA metabolic process#GO:0006259		DNA-directed DNA polymerase#PC00018	
ECOLI|EnsemblGenome=b1696|UniProtKB=P77402	P77402	ydiP	PTHR43280:SF17	ARAC-FAMILY TRANSCRIPTIONAL REGULATOR	TRANSCRIPTION REGULATOR, ARAC FAMILY	DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355		helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b0997|UniProtKB=P33225	P33225	torA	PTHR43742:SF4	TRIMETHYLAMINE-N-OXIDE REDUCTASE	TRIMETHYLAMINE-N-OXIDE REDUCTASE 1	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	anaerobic respiration#GO:0009061;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152	periplasmic space#GO:0042597;extracellular region#GO:0005576;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313	reductase#PC00198	
ECOLI|EnsemblGenome=b2491|UniProtKB=P71229	P71229	hyfR	PTHR32071:SF123	TRANSCRIPTIONAL REGULATORY PROTEIN	DNA-BINDING TRANSCRIPTIONAL ACTIVATOR HYFR-RELATED	DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789	protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991	DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b2209|UniProtKB=P23827	P23827	eco	PTHR35890:SF4	FAMILY NOT NAMED	ECOTIN	enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678		periplasmic space#GO:0042597;extracellular region#GO:0005576;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313	protease inhibitor#PC00191	
ECOLI|EnsemblGenome=b2546|UniProtKB=P77315	P77315	yphD	PTHR32196:SF21	ABC TRANSPORTER PERMEASE PROTEIN YPHD-RELATED-RELATED	ABC TRANSPORTER PERMEASE PROTEIN YPHD-RELATED			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0015|UniProtKB=P08622	P08622	dnaJ	PTHR43096:SF48	DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED	CHAPERONE PROTEIN DNAJ		primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein refolding#GO:0042026	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	chaperone#PC00072	
ECOLI|EnsemblGenome=b2349|UniProtKB=P37326	P37326	intS	PTHR30629:SF2	PROPHAGE INTEGRASE	PROPHAGE INTEGRASE INTS-RELATED					
ECOLI|EnsemblGenome=b2947|UniProtKB=P04425	P04425	gshB	PTHR21621:SF4	RIBOSOMAL PROTEIN S6 MODIFICATION PROTEIN	GLUTATHIONE SYNTHETASE	ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879	metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;biosynthetic process#GO:0009058;peptide metabolic process#GO:0006518	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	translational protein#PC00263;ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b1634|UniProtKB=P77304	P77304	dtpA	PTHR11654:SF99	OLIGOPEPTIDE TRANSPORTER-RELATED	DIPEPTIDE AND TRIPEPTIDE PERMEASE A	monoatomic cation transmembrane transporter activity#GO:0008324;solute:proton symporter activity#GO:0015295;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;oligopeptide transmembrane transporter activity#GO:0035673;proton transmembrane transporter activity#GO:0015078;dipeptide transmembrane transporter activity#GO:0071916;transporter activity#GO:0005215;tripeptide transmembrane transporter activity#GO:0042937;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291	establishment of localization#GO:0051234;dipeptide transport#GO:0042938;transmembrane transport#GO:0055085;localization#GO:0051179;oligopeptide transport#GO:0006857;transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;cellular process#GO:0009987;oligopeptide transmembrane transport#GO:0035672	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b4084|UniProtKB=P32718	P32718	alsK	PTHR18964:SF174	ROK (REPRESSOR, ORF, KINASE) FAMILY	D-ALLOSE KINASE-RELATED	hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740			winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b2509|UniProtKB=P04994	P04994	xseA	PTHR30008:SF0	EXODEOXYRIBONUCLEASE 7 LARGE SUBUNIT	EXODEOXYRIBONUCLEASE 7 LARGE SUBUNIT				exodeoxyribonuclease#PC00098	
ECOLI|EnsemblGenome=b0396|UniProtKB=P23910	P23910	araJ	PTHR43124:SF6	PURINE EFFLUX PUMP PBUE	TRANSPORTER ARAJ-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b1163|UniProtKB=P75990	P75990	bluF	PTHR33121:SF15	CYCLIC DI-GMP PHOSPHODIESTERASE PDEF	BLUE LIGHT- AND TEMPERATURE-REGULATED ANTIREPRESSOR BLUF	hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578	regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular process#GO:0050794	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121	
ECOLI|EnsemblGenome=b1895|UniProtKB=P46888	P46888	uspC	PTHR46268:SF16	STRESS RESPONSE PROTEIN NHAX	UNIVERSAL STRESS PROTEIN C		response to stimulus#GO:0050896;response to stress#GO:0006950			
ECOLI|EnsemblGenome=b2908|UniProtKB=P15034	P15034	pepP	PTHR43226:SF9	XAA-PRO AMINOPEPTIDASE 3	XAA-PRO AMINOPEPTIDASE	peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824	protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987		metalloprotease#PC00153	
ECOLI|EnsemblGenome=b0523|UniProtKB=P0AG18	P0AG18	purE	PTHR23046:SF2	PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC SUBUNIT	PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE	isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824		cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;lyase#PC00144	De novo purine biosynthesis#P02738>N5-carboxyaminoimidazole ribonucleotide synthase#P02906;De novo purine biosynthesis#P02738>N5-carboxyaminoimidazole ribonucleotide mutase#P02911
ECOLI|EnsemblGenome=b0592|UniProtKB=P0AEL6	P0AEL6	fepB	PTHR30532:SF24	IRON III  DICITRATE-BINDING PERIPLASMIC PROTEIN	FERRIC ENTEROBACTIN-BINDING PERIPLASMIC PROTEIN FEPB		cellular process#GO:0009987;establishment of localization in cell#GO:0051649;monoatomic ion homeostasis#GO:0050801;siderophore-iron import into cell#GO:0033214;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;iron coordination entity transport#GO:1901678;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;import into cell#GO:0098657;intracellular monoatomic ion homeostasis#GO:0006873;iron import into cell#GO:0033212;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular iron ion homeostasis#GO:0006879;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;iron ion transport#GO:0006826;monoatomic ion transport#GO:0006811;siderophore-dependent iron import pathway#GO:0180060;cellular localization#GO:0051641;monoatomic cation transport#GO:0006812;localization#GO:0051179	cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313;extracellular region#GO:0005576;periplasmic space#GO:0042597		
ECOLI|EnsemblGenome=b3247|UniProtKB=P0A9J0	P0A9J0	rng	PTHR30001:SF0	RIBONUCLEASE	RIBONUCLEASE G	catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540	ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	endoribonuclease#PC00094;RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b3703|UniProtKB=P0A7P5	P0A7P5	rpmH	PTHR14503:SF14	MITOCHONDRIAL RIBOSOMAL PROTEIN 34 FAMILY MEMBER	LARGE RIBOSOMAL SUBUNIT PROTEIN BL34				ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b2037|UniProtKB=P37746	P37746	rfbX	PTHR30250:SF11	PST FAMILY PREDICTED COLANIC ACID TRANSPORTER	INNER MEMBRANE PROTEIN YGHQ-RELATED			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b1520|UniProtKB=P76146	P76146	yneE	PTHR33281:SF24	UPF0187 PROTEIN YNEE	VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE	monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic anion channel activity#GO:0008308;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;voltage-gated channel activity#GO:0022832;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b2378|UniProtKB=P0ACV2	P0ACV2	lpxP	PTHR30606:SF7	LIPID A BIOSYNTHESIS LAUROYL ACYLTRANSFERASE	LIPID A BIOSYNTHESIS PALMITOLEOYLTRANSFERASE	acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740	lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;liposaccharide metabolic process#GO:1903509;lipid A biosynthetic process#GO:0009245;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247	membrane#GO:0016020;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;acyltransferase#PC00042	
ECOLI|EnsemblGenome=b0507|UniProtKB=P0AEP7	P0AEP7	gcl	PTHR18968:SF14	THIAMINE PYROPHOSPHATE ENZYMES	GLYOXYLATE CARBOLIGASE	nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;transketolase or transaldolase activity#GO:0016744;carboxy-lyase activity#GO:0016831;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363	carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;branched-chain amino acid biosynthetic process#GO:0009082;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038	catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	metabolite interconversion enzyme#PC00262;ligase#PC00142	Allantoin degradation#P02725>Glyoxylate carboligase#P02819
ECOLI|EnsemblGenome=b3184|UniProtKB=P0AA73	P0AA73	yhbE	PTHR22911:SF134	ACYL-MALONYL CONDENSING ENZYME-RELATED	GLR1986 PROTEIN			cellular anatomical structure#GO:0110165;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b4198|UniProtKB=P39306	P39306	ulaF	PTHR22789:SF9	FUCULOSE PHOSPHATE ALDOLASE	L-RIBULOSE-5-PHOSPHATE 4-EPIMERASE ULAF	carbon-carbon lyase activity#GO:0016830;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;aldehyde-lyase activity#GO:0016832;isomerase activity#GO:0016853;lyase activity#GO:0016829	carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;cellular process#GO:0009987	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	aldolase#PC00044;lyase#PC00144	Ascorbate degradation#P02729>L-ribulose-5-phosphate-4-epimerase#P02851
ECOLI|EnsemblGenome=b0210|UniProtKB=P30866	P30866	yafE	PTHR42912:SF93	METHYLTRANSFERASE	THIOL S-METHYLTRANSFERASE TMT1A	transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;catalytic activity#GO:0003824			methyltransferase#PC00155;transferase#PC00220	
ECOLI|EnsemblGenome=b1103|UniProtKB=P0ACE7	P0ACE7	hinT	PTHR23089:SF53	HISTIDINE TRIAD  HIT  PROTEIN	PURINE NUCLEOSIDE PHOSPHORAMIDASE	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	nucleotide phosphatase#PC00173	
ECOLI|EnsemblGenome=b3701|UniProtKB=P0A988	P0A988	dnaN	PTHR30478:SF0	DNA POLYMERASE III SUBUNIT BETA	BETA SLIDING CLAMP		nucleobase-containing compound metabolic process#GO:0006139;DNA strand elongation involved in DNA replication#GO:0006271;cellular process#GO:0009987;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259		DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b3829|UniProtKB=P25665	P25665	metE	PTHR30519:SF0	5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE	5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168	small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;proteinogenic amino acid biosynthetic process#GO:0170038;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;aspartate family amino acid biosynthetic process#GO:0009067;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	methyltransferase#PC00155;transferase#PC00220	
ECOLI|EnsemblGenome=b3935|UniProtKB=P17888	P17888	priA	PTHR30580:SF0	PRIMOSOMAL PROTEIN N	REPLICATION RESTART PROTEIN PRIA	macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094	cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA replication initiation#GO:0006270;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139			
ECOLI|EnsemblGenome=b2287|UniProtKB=P0AFC7	P0AFC7	nuoB	PTHR11995:SF14	NADH DEHYDROGENASE	NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL	electron transfer activity#GO:0009055;oxidoreductase activity, acting on NAD(P)H#GO:0016651;monoatomic cation transmembrane transporter activity#GO:0008324;NADH dehydrogenase activity#GO:0003954;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	monoatomic ion transport#GO:0006811;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;establishment of localization#GO:0051234;cellular respiration#GO:0045333;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987	respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351	oxidoreductase#PC00176;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b1713|UniProtKB=P07395	P07395	pheT	PTHR10947:SF0	PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47	PHENYLALANINE--TRNA LIGASE BETA SUBUNIT	ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101	tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070	catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165	translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047	
ECOLI|EnsemblGenome=b3010|UniProtKB=Q46855	Q46855	yqhC	PTHR43436:SF2	ARAC-FAMILY TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR YQHC	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789		DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b0576|UniProtKB=P24207	P24207	pheP	PTHR43495:SF3	GABA PERMEASE	PHENYLALANINE-SPECIFIC PERMEASE	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227;secondary carrier transporter#PC00258;amino acid transporter#PC00046	
ECOLI|EnsemblGenome=b3363|UniProtKB=P0AFL3	P0AFL3	ppiA	PTHR43246:SF13	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE CYP38, CHLOROPLASTIC	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A	peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824		periplasmic space#GO:0042597;extracellular region#GO:0005576;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313	chaperone#PC00072	
ECOLI|EnsemblGenome=b0023|UniProtKB=P0A7U7	P0A7U7	rpsT	PTHR33398:SF7	30S RIBOSOMAL PROTEIN S20	SMALL RIBOSOMAL SUBUNIT PROTEIN BS20	nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;binding#GO:0005488;RNA binding#GO:0003723		cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622	ribosomal protein#PC00202;translational protein#PC00263	
ECOLI|EnsemblGenome=b3627|UniProtKB=P27128	P27128	waaO	PTHR13778:SF76	GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN	LIPOPOLYSACCHARIDE GLUCOSYLTRANSFERASE WAAO	hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757			transferase#PC00220;glycosyltransferase#PC00111	
ECOLI|EnsemblGenome=b1204|UniProtKB=P0A7D1	P0A7D1	pth	PTHR17224:SF1	PEPTIDYL-TRNA HYDROLASE	PEPTIDYL-TRNA HYDROLASE	hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787			hydrolase#PC00121;esterase#PC00097	
ECOLI|EnsemblGenome=b1201|UniProtKB=P76016	P76016	dhaR	PTHR32071:SF117	TRANSCRIPTIONAL REGULATORY PROTEIN	PTS-DEPENDENT DIHYDROXYACETONE KINASE OPERON REGULATORY PROTEIN-RELATED	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110	regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252	protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991	DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b1022|UniProtKB=P75905	P75905	pgaC	PTHR43630:SF1	POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE SYNTHASE	POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE SYNTHASE	catalytic activity#GO:0003824;transferase activity#GO:0016740			glycosyltransferase#PC00111	
ECOLI|EnsemblGenome=b0679|UniProtKB=P09323	P09323	nagE	PTHR30009:SF4	CYTOCHROME C-TYPE SYNTHESIS PROTEIN AND PTS TRANSMEMBRANE COMPONENT	PTS SYSTEM N-ACETYLGLUCOSAMINE-SPECIFIC EIICBA COMPONENT	carbohydrate transmembrane transporter activity#GO:0015144;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein-phosphocysteine-sugar phosphotransferase activity#GO:0090563;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824	carbohydrate transport#GO:0008643;transport#GO:0006810;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;localization#GO:0051179;transmembrane transport#GO:0055085;import into cell#GO:0098657;establishment of localization#GO:0051234;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;import across plasma membrane#GO:0098739;carbohydrate transmembrane transport#GO:0034219	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b1078|UniProtKB=P0ABX5	P0ABX5	flgG	PTHR30435:SF19	FLAGELLAR PROTEIN	FLAGELLAR BASAL-BODY ROD PROTEIN FLGG		bacterial-type flagellum-dependent cell motility#GO:0071973;cell motility#GO:0048870;archaeal or bacterial-type flagellum-dependent cell motility#GO:0097588;bacterial-type flagellum-dependent swarming motility#GO:0071978;cilium or flagellum-dependent cell motility#GO:0001539;cellular process#GO:0009987	bacterial-type flagellum#GO:0009288;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;cell projection#GO:0042995	structural protein#PC00211	
ECOLI|EnsemblGenome=b1317|UniProtKB=P77366	P77366	ycjU	PTHR18901:SF38	2-DEOXYGLUCOSE-6-PHOSPHATE PHOSPHATASE 2	BETA-PHOSPHOGLUCOMUTASE				phosphatase#PC00181;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3047|UniProtKB=P77616	P77616	yqiH	PTHR30251:SF5	PILUS ASSEMBLY CHAPERONE	FIMBRIAL CHAPARONE PROTEIN		gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152	periplasmic space#GO:0042597;extracellular region#GO:0005576;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313	chaperone#PC00072	
ECOLI|EnsemblGenome=b1588|UniProtKB=P77783	P77783	ynfF	PTHR43742:SF1	TRIMETHYLAMINE-N-OXIDE REDUCTASE	DIMETHYL SULFOXIDE REDUCTASE CHAIN YNFF-RELATED	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;anaerobic respiration#GO:0009061;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333	cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;extracellular region#GO:0005576;periplasmic space#GO:0042597	reductase#PC00198	
ECOLI|EnsemblGenome=b1393|UniProtKB=P76082	P76082	paaF	PTHR11941:SF54	ENOYL-COA HYDRATASE-RELATED	2,3-DEHYDROADIPYL-COA HYDRATASE-RELATED		metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282		metabolite interconversion enzyme#PC00262;lyase#PC00144;hydratase#PC00120	Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163
ECOLI|EnsemblGenome=b3812|UniProtKB=P0ADP0	P0ADP0	yigB	PTHR46470:SF4	N-ACYLNEURAMINATE-9-PHOSPHATASE	5-AMINO-6-(5-PHOSPHO-D-RIBITYLAMINO)URACIL PHOSPHATASE YIGB		metabolic process#GO:0008152;cellular process#GO:0009987;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;flavin-containing compound metabolic process#GO:0042726;biosynthetic process#GO:0009058		metabolite interconversion enzyme#PC00262;phosphatase#PC00181	
ECOLI|EnsemblGenome=b0965|UniProtKB=P75874	P75874	yccU	PTHR33303:SF2	CYTOPLASMIC PROTEIN-RELATED	COA-BINDING DOMAIN-CONTAINING PROTEIN			cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		
ECOLI|EnsemblGenome=b4472|UniProtKB=P46474	P46474	yhdP	PTHR38690:SF1	PROTEASE-RELATED	INTERMEMBRANE PHOSPHOLIPID TRANSPORTER YHDP		phospholipid transport#GO:0015914;lipid transport#GO:0006869;organophosphate ester transport#GO:0015748;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;lipid localization#GO:0010876		protease#PC00190	
ECOLI|EnsemblGenome=b2995|UniProtKB=P37180	P37180	hybB	PTHR30074:SF4	FORMATE DEHYDROGENASE, NITRATE-INDUCIBLE, CYTOCHROME B556 FDN  SUBUNIT	NI_FE-HYDROGENASE 2 B-TYPE CYTOCHROME SUBUNIT-RELATED	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;anaerobic respiration#GO:0009061;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3211|UniProtKB=P0ADW6	P0ADW6	yhcC	PTHR11135:SF1	HISTONE ACETYLTRANSFERASE-RELATED	PROTEIN YHCC				histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077	
ECOLI|EnsemblGenome=b0243|UniProtKB=P07004	P07004	proA	PTHR11063:SF8	GLUTAMATE SEMIALDEHYDE DEHYDROGENASE	GAMMA-GLUTAMYL PHOSPHATE REDUCTASE	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491			dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	Proline biosynthesis#P02768>Glutamate semialdehyde dehydrogenase#P03112
ECOLI|EnsemblGenome=b4231|UniProtKB=P37772	P37772	yjfF	PTHR32196:SF63	ABC TRANSPORTER PERMEASE PROTEIN YPHD-RELATED-RELATED	INNER MEMBRANE ABC TRANSPORTER PERMEASE PROTEIN YJFF			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b3366|UniProtKB=P0A9I8	P0A9I8	nirD	PTHR40562:SF1	FAMILY NOT NAMED	NITRITE REDUCTASE (NADH) SMALL SUBUNIT	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491		catalytic complex#GO:1902494;protein-containing complex#GO:0032991		
ECOLI|EnsemblGenome=b3221|UniProtKB=P45424	P45424	nanQ	PTHR34986:SF5	EVOLVED BETA-GALACTOSIDASE SUBUNIT BETA	N-ACETYLNEURAMINATE ANOMERASE NANQ			intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;galactosidase#PC00104	
ECOLI|EnsemblGenome=b2895|UniProtKB=P0ABY4	P0ABY4	fldB	PTHR42809:SF3	FLAVODOXIN 2	FLAVODOXIN 2					
ECOLI|EnsemblGenome=b4475|UniProtKB=P46849	P46849	rtcA	PTHR11096:SF3	RNA 3' TERMINAL PHOSPHATE CYCLASE	RNA 3'-TERMINAL PHOSPHATE CYCLASE	catalytic activity, acting on RNA#GO:0140098;cyclase activity#GO:0009975;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640			RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b1687|UniProtKB=P77748	P77748	ydiJ	PTHR11748:SF119	D-LACTATE DEHYDROGENASE	D-2-HYDROXYGLUTARATE DEHYDROGENASE				dehydrogenase#PC00092;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3750|UniProtKB=P0AGI1	P0AGI1	rbsC	PTHR32196:SF21	ABC TRANSPORTER PERMEASE PROTEIN YPHD-RELATED-RELATED	ABC TRANSPORTER PERMEASE PROTEIN YPHD-RELATED			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0773|UniProtKB=P12994	P12994	ybhB	PTHR30289:SF12	UNCHARACTERIZED PROTEIN YBCL-RELATED	UPF0098 PROTEIN YBHB			extracellular region#GO:0005576;periplasmic space#GO:0042597;cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288		
ECOLI|EnsemblGenome=b1423|UniProtKB=P76097	P76097	ydcJ	PTHR39479:SF2	FAMILY NOT NAMED	2-OXOADIPATE DIOXYGENASE_DECARBOXYLASE					
ECOLI|EnsemblGenome=b1237|UniProtKB=P0ACF8	P0ACF8	hns	PTHR38097:SF1	FAMILY NOT NAMED	DNA-BINDING PROTEIN H-NS	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110		protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b3607|UniProtKB=P0A9D4	P0A9D4	cysE	PTHR42811:SF5	SERINE ACETYLTRANSFERASE	SERINE ACETYLTRANSFERASE-RELATED	acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747	proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	transferase#PC00220;acetyltransferase#PC00038	Cysteine biosynthesis#P02737>Serine acetyltransferase#P02888
ECOLI|EnsemblGenome=b3468|UniProtKB=P0ADI9	P0ADI9	yhhN	PTHR31885:SF6	GH04784P	LYSOPLASMALOGENASE	catalytic activity#GO:0003824;hydrolase activity#GO:0016787		cellular anatomical structure#GO:0110165;membrane#GO:0016020		
ECOLI|EnsemblGenome=b3033|UniProtKB=P0ADU7	P0ADU7	yqiB	PTHR38774:SF1	CYTOPLASMIC PROTEIN-RELATED	DUF1249 DOMAIN-CONTAINING PROTEIN					
ECOLI|EnsemblGenome=b0722|UniProtKB=P0AC44	P0AC44	sdhD	PTHR38689:SF1	SUCCINATE DEHYDROGENASE HYDROPHOBIC MEMBRANE ANCHOR SUBUNIT	SUCCINATE DEHYDROGENASE HYDROPHOBIC MEMBRANE ANCHOR SUBUNIT	tetrapyrrole binding#GO:0046906;heme binding#GO:0020037;binding#GO:0005488	cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	
ECOLI|Gene_OrderedLocusName=JW3386|UniProtKB=P0ACL0	P0ACL0	glpR	PTHR30363:SF4	HTH-TYPE TRANSCRIPTIONAL REGULATOR SRLR-RELATED	GLYCEROL-3-PHOSPHATE REGULON REPRESSOR	transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252		helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b3336|UniProtKB=P0ABD3	P0ABD3	bfr	PTHR30295:SF0	BACTERIOFERRITIN	BACTERIOFERRITIN	oxidoreductase activity#GO:0016491;iron ion binding#GO:0005506;oxidoreductase activity, acting on metal ions#GO:0016722;catalytic activity#GO:0003824;heme binding#GO:0020037;metal ion binding#GO:0046872;tetrapyrrole binding#GO:0046906;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	storage protein#PC00210	
ECOLI|EnsemblGenome=b3315|UniProtKB=P61175	P61175	rplV	PTHR13501:SF8	CHLOROPLAST 50S RIBOSOMAL PROTEIN L22-RELATED	LARGE RIBOSOMAL SUBUNIT PROTEIN UL22	structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735	biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152	ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904	ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b3043|UniProtKB=P39834	P39834	ygiL	PTHR33420:SF11	FIMBRIAL SUBUNIT ELFA-RELATED	FIMBRIAL-LIKE PROTEIN		cell-substrate adhesion#GO:0031589;single-species biofilm formation#GO:0044010;cell adhesion#GO:0007155;cellular process#GO:0009987	cell projection#GO:0042995;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0866|UniProtKB=P0A8C1	P0A8C1	ybjQ	PTHR34068:SF1	UPF0145 PROTEIN YBJQ	UPF0145 PROTEIN YBJQ					
ECOLI|EnsemblGenome=b3341|UniProtKB=P02359	P02359	rpsG	PTHR11205:SF69	RIBOSOMAL PROTEIN S7	SMALL RIBOSOMAL SUBUNIT PROTEIN US7	RNA binding#GO:0003723;structural molecule activity#GO:0005198;nucleic acid binding#GO:0003676;binding#GO:0005488;rRNA binding#GO:0019843;structural constituent of ribosome#GO:0003735;mRNA binding#GO:0003729	biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152	cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622	translational protein#PC00263;ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b0771|UniProtKB=P75764	P75764	ybhJ	PTHR43160:SF5	ACONITATE HYDRATASE B	ACONITATE HYDRATASE A	catalytic activity#GO:0003824;binding#GO:0005488;small molecule binding#GO:0036094;hydro-lyase activity#GO:0016836;iron-sulfur cluster binding#GO:0051536;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829	generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238		lyase#PC00144;hydratase#PC00120	TCA cycle#P00051>Aconitase#P01268
ECOLI|EnsemblGenome=b1941|UniProtKB=P52612	P52612	fliI	PTHR15184:SF81	ATP SYNTHASE	FLAGELLUM-SPECIFIC ATP SYNTHASE	channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;ligase activity#GO:0016874;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;proton channel activity#GO:0015252		transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting ATP synthase complex#GO:0045259;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020	ATP synthase#PC00002	
ECOLI|EnsemblGenome=b2751|UniProtKB=P23845	P23845	cysN	PTHR23115:SF307	TRANSLATION FACTOR	SULFATE ADENYLYLTRANSFERASE SUBUNIT 1		metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987		translation factor#PC00223	
ECOLI|EnsemblGenome=b2799|UniProtKB=P0A9S1	P0A9S1	fucO	PTHR11496:SF106	ALCOHOL DEHYDROGENASE	LACTALDEHYDE REDUCTASE	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491			dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b1654|UniProtKB=P0AC69	P0AC69	grxD	PTHR10293:SF72	GLUTAREDOXIN FAMILY MEMBER	MONOTHIOL GLUTAREDOXIN-S14, CHLOROPLASTIC	disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824	iron-sulfur cluster assembly#GO:0016226;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043		oxidoreductase#PC00176;reductase#PC00198	
ECOLI|EnsemblGenome=b3342|UniProtKB=P0A7S3	P0A7S3	rpsL	PTHR11652:SF1	30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER	SMALL RIBOSOMAL SUBUNIT PROTEIN US12M	structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198	macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170	cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;ribosome#GO:0005840;intracellular organelle#GO:0043229	ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b3147|UniProtKB=P45464	P45464	lpoA	PTHR38038:SF1	PENICILLIN-BINDING PROTEIN ACTIVATOR LPOA	PENICILLIN-BINDING PROTEIN ACTIVATOR LPOA	enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772	carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;cell wall macromolecule biosynthetic process#GO:0044038;biosynthetic process#GO:0009058;cell wall organization or biogenesis#GO:0071554;peptidoglycan metabolic process#GO:0000270;metabolic process#GO:0008152;peptidoglycan-based cell wall biogenesis#GO:0009273;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;glycosaminoglycan biosynthetic process#GO:0006024;carbohydrate derivative biosynthetic process#GO:1901137;glycosaminoglycan metabolic process#GO:0030203;aminoglycan biosynthetic process#GO:0006023;peptidoglycan biosynthetic process#GO:0009252;aminoglycan metabolic process#GO:0006022;cell wall macromolecule metabolic process#GO:0044036;cell wall biogenesis#GO:0042546	side of membrane#GO:0098552;outer membrane#GO:0019867;extracellular region#GO:0005576;cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;membrane#GO:0016020;cell outer membrane#GO:0009279;external encapsulating structure#GO:0030312		
ECOLI|EnsemblGenome=b1409|UniProtKB=P76091	P76091	ynbB	PTHR43535:SF1	PHOSPHATIDATE CYTIDYLYLTRANSFERASE	PHOSPHATIDATE CYTIDYLYLTRANSFERASE YNBB-RELATED			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transferase#PC00220	
ECOLI|EnsemblGenome=b3849|UniProtKB=P0AFZ7	P0AFZ7	trkH	PTHR32024:SF2	TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKG-RELATED	TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKG-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324	transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1007|UniProtKB=P75893	P75893	rutF	PTHR30466:SF1	FLAVIN REDUCTASE	FMN REDUCTASE (NADH) RUTF	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			oxidoreductase#PC00176;reductase#PC00198	
ECOLI|EnsemblGenome=b4096|UniProtKB=P16679	P16679	phnL	PTHR42798:SF9	LIPOPROTEIN-RELEASING SYSTEM ATP-BINDING PROTEIN LOLD	ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE SYNTHASE SUBUNIT PHNL		localization#GO:0051179;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;transport#GO:0006810		ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b3532|UniProtKB=P37652	P37652	bcsB	PTHR39083:SF1	CYCLIC DI-GMP-BINDING PROTEIN	CYCLIC DI-GMP-BINDING PROTEIN			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b1776|UniProtKB=P77539	P77539	ydjL	PTHR43350:SF19	NAD-DEPENDENT ALCOHOL DEHYDROGENASE	D-GULOSIDE 3-DEHYDROGENASE	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1655|UniProtKB=P76190	P76190	mepH	PTHR47053:SF1	MUREIN DD-ENDOPEPTIDASE MEPH-RELATED	MUREIN DD-ENDOPEPTIDASE MEPH-RELATED	catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787	macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;peptidoglycan metabolic process#GO:0000270;aminoglycan metabolic process#GO:0006022;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987			
ECOLI|EnsemblGenome=b4166|UniProtKB=P39288	P39288	queG	PTHR30002:SF4	EPOXYQUEUOSINE REDUCTASE	EPOXYQUEUOSINE REDUCTASE	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble base modification#GO:0002097;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059		oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b4233|UniProtKB=P37773	P37773	mpl	PTHR43445:SF5	UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE-RELATED	UDP-N-ACETYLMURAMATE--L-ALANYL-GAMMA-D-GLUTAMYL-MESO-2,6-DIAMINOHEPTANDIOATE LIGASE	catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879	macromolecule metabolic process#GO:0043170;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;peptidoglycan metabolic process#GO:0000270;peptidoglycan turnover#GO:0009254;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycosaminoglycan metabolic process#GO:0030203	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	ligase#PC00142	
ECOLI|EnsemblGenome=b1489|UniProtKB=P76129	P76129	dosP	PTHR33121:SF70	CYCLIC DI-GMP PHOSPHODIESTERASE PDEF	OXYGEN SENSOR PROTEIN DOSP	phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	hydrolase#PC00121;phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3346|UniProtKB=P64624	P64624	yheO	PTHR35568:SF1	TRANSCRIPTIONAL REGULATOR DAUR	TRANSCRIPTIONAL REGULATOR DAUR			cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b1512|UniProtKB=P76141	P76141	lsrR	PTHR34294:SF1	TRANSCRIPTIONAL REGULATOR-RELATED	TRANSCRIPTIONAL REGULATOR LSRR	binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of DNA-templated transcription initiation#GO:2000142;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889		DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b4383|UniProtKB=P0A6K6	P0A6K6	deoB	PTHR21110:SF0	PHOSPHOPENTOMUTASE	PHOSPHOPENTOMUTASE	catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;intramolecular phosphotransferase activity#GO:0016868;isomerase activity#GO:0016853	response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	mutase#PC00160;isomerase#PC00135	PRPP biosynthesis#P02760>Phosphopentose mutase#P03064
ECOLI|EnsemblGenome=b1270|UniProtKB=P0A9H5	P0A9H5	btuR	PTHR46638:SF1	CORRINOID ADENOSYLTRANSFERASE	CORRINOID ADENOSYLTRANSFERASE		tetrapyrrole biosynthetic process#GO:0033014;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;cellular process#GO:0009987;small molecule biosynthetic process#GO:0044283		metabolite interconversion enzyme#PC00262;transferase#PC00220	
ECOLI|EnsemblGenome=b1772|UniProtKB=P77493	P77493	ydjH	PTHR43085:SF1	HEXOKINASE FAMILY MEMBER	L-GLYCERO-L-GALACTO-OCTULURONATE KINASE-RELATED	kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740			transferase#PC00220;metabolite interconversion enzyme#PC00262;carbohydrate kinase#PC00065	
ECOLI|EnsemblGenome=b2717|UniProtKB=P0AEV9	P0AEV9	hycI	PTHR30302:SF4	HYDROGENASE 1 MATURATION PROTEASE	HYDROGENASE 3 MATURATION PROTEASE	catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787	protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238		protease#PC00190;aspartic protease#PC00053	
ECOLI|EnsemblGenome=b2315|UniProtKB=P08192	P08192	folC	PTHR11136:SF0	FOLYLPOLYGLUTAMATE SYNTHASE-RELATED	DIHYDROFOLATE SYNTHETASE-RELATED	catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879	pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;biosynthetic process#GO:0009058;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	ligase#PC00142	Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate synthase#P02958;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943
ECOLI|EnsemblGenome=b0180|UniProtKB=P0A6Q6	P0A6Q6	fabZ	PTHR30272:SF1	3-HYDROXYACYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE	3-HYDROXYACYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE	catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836	small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283		dehydratase#PC00091	
ECOLI|EnsemblGenome=b3386|UniProtKB=P0AG07	P0AG07	rpe	PTHR11749:SF3	RIBULOSE-5-PHOSPHATE-3-EPIMERASE	RIBULOSE-PHOSPHATE 3-EPIMERASE	isomerase activity#GO:0016853;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;D-ribulose-phosphate 3-epimerase activity#GO:0004750	nucleotide metabolic process#GO:0009117;pentose-phosphate shunt#GO:0006098;pyridine-containing compound metabolic process#GO:0072524;glyceraldehyde-3-phosphate metabolic process#GO:0019682;NADPH regeneration#GO:0006740;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt, non-oxidative branch#GO:0009052;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		Ascorbate degradation#P02729>L-xylulose-5-phosphate-3-epimerase#P02852
ECOLI|EnsemblGenome=b2290|UniProtKB=P0A959	P0A959	alaA	PTHR43488:SF3	GLUTAMATE-PYRUVATE AMINOTRANSFERASE ALAA	GLUTAMATE-PYRUVATE AMINOTRANSFERASE ALAA	catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483	carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283		transaminase#PC00216	
ECOLI|EnsemblGenome=b1866|UniProtKB=P21889	P21889	aspS	PTHR22594:SF5	ASPARTYL/LYSYL-TRNA SYNTHETASE	ASPARTATE--TRNA LIGASE	catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640	tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307		aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263	
ECOLI|EnsemblGenome=b3917|UniProtKB=P0AG78	P0AG78	sbp	PTHR30368:SF2	SULFATE-BINDING PROTEIN	SULFATE-BINDING PROTEIN	binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167	sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987	cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;extracellular region#GO:0005576;periplasmic space#GO:0042597		
ECOLI|EnsemblGenome=b3404|UniProtKB=P0AEJ4	P0AEJ4	envZ	PTHR44936:SF5	SENSOR PROTEIN CREC	SENSOR HISTIDINE KINASE ENVZ	transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphorelay sensor kinase activity#GO:0000155;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein histidine kinase activity#GO:0004673;catalytic activity, acting on a protein#GO:0140096;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b1478|UniProtKB=P39451	P39451	adhP	PTHR42683:SF78	ALDEHYDE REDUCTASE	ALCOHOL DEHYDROGENASE, PROPANOL-PREFERRING	oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824	metabolic process#GO:0008152;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;catabolic process#GO:0009056;aldehyde catabolic process#GO:0046185		oxidoreductase#PC00176	
ECOLI|Gene_OrderedLocusName=JW5571|UniProtKB=P0DTT0	P0DTT0	bipA	PTHR42908:SF8	TRANSLATION ELONGATION FACTOR-RELATED	TR-TYPE G DOMAIN-CONTAINING PROTEIN	ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462		cytosol#GO:0005829;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	translation elongation factor#PC00222	
ECOLI|EnsemblGenome=b2776|UniProtKB=P55138	P55138	ygcE	PTHR43095:SF5	SUGAR KINASE	XYLULOSE KINASE	transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824			carbohydrate kinase#PC00065	Ascorbate degradation#P02729>L-xylulose kinase#P02849
ECOLI|EnsemblGenome=b3141|UniProtKB=P42912	P42912	agaI	PTHR11280:SF5	GLUCOSAMINE-6-PHOSPHATE ISOMERASE	GLUCOSAMINE-6-PHOSPHATE DEAMINASE	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;protein binding#GO:0005515;hydrolase activity#GO:0016787;deaminase activity#GO:0019239;identical protein binding#GO:0042802;binding#GO:0005488;catalytic activity#GO:0003824	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino sugar catabolic process#GO:0046348;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;amino sugar metabolic process#GO:0006040;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	isomerase#PC00135	N-acetylglucosamine metabolism#P02756>Glucosamine-6-phosphate deaminase#P03041
ECOLI|EnsemblGenome=b4334|UniProtKB=P39383	P39383	yjiL	PTHR32329:SF2	BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED	BADF_BADG_BCRA_BCRD ATPASE				dehydratase#PC00091;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1145|UniProtKB=P75974	P75974	cohE	PTHR33516:SF2	LEXA REPRESSOR	LEXA REPRESSOR-RELATED	transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;DNA-binding transcription repressor activity#GO:0001217;DNA binding#GO:0003677	DNA damage response#GO:0006974;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;SOS response#GO:0009432;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to stress#GO:0033554;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794	protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991	Lambda repressor-like transcription factor#PC00245;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b1008|UniProtKB=P75894	P75894	rutE	PTHR43543:SF2	MALONIC SEMIALDEHYDE REDUCTASE RUTE-RELATED	MALONIC SEMIALDEHYDE REDUCTASE RUTE-RELATED				oxidoreductase#PC00176;peroxidase#PC00180;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b4081|UniProtKB=P32715	P32715	mdtO	PTHR30509:SF9	P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT-RELATED	P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0928|UniProtKB=P00509	P00509	aspC	PTHR11879:SF59	ASPARTATE AMINOTRANSFERASE	ASPARTATE AMINOTRANSFERASE	transaminase activity#GO:0008483;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;protein binding#GO:0005515;transferase activity#GO:0016740;catalytic activity#GO:0003824;identical protein binding#GO:0042802;heterocyclic compound binding#GO:1901363	cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;aromatic amino acid biosynthetic process#GO:0009073;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	metabolite interconversion enzyme#PC00262;transferase#PC00220;transaminase#PC00216	Asparagine and aspartate biosynthesis#P02730>Aspartate aminotransferase#P02854
ECOLI|EnsemblGenome=b0355|UniProtKB=P51025	P51025	frmB	PTHR10061:SF0	S-FORMYLGLUTATHIONE HYDROLASE	S-FORMYLGLUTATHIONE HYDROLASE	hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790		cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	serine protease#PC00203;protein modifying enzyme#PC00260	
ECOLI|EnsemblGenome=b1232|UniProtKB=P37051	P37051	purU	PTHR42706:SF6	FORMYLTETRAHYDROFOLATE DEFORMYLASE	FORMYLTETRAHYDROFOLATE DEFORMYLASE	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811	cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;tetrahydrofolate metabolic process#GO:0046653;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;hydrolase#PC00121	Tetrahydrofolate biosynthesis#P02742>Phosphoribosylglycinamide formyltransferase#P02944;Formyltetrahydrofolate biosynthesis#P02743>Formyl tetrahydrofolate deformylase#P02956
ECOLI|EnsemblGenome=b1939|UniProtKB=P0ABZ1	P0ABZ1	fliG	PTHR30534:SF0	FLAGELLAR MOTOR SWITCH PROTEIN FLIG	FLAGELLAR MOTOR SWITCH PROTEIN FLIG				structural protein#PC00211	
ECOLI|EnsemblGenome=b2213|UniProtKB=P06134	P06134	ada	PTHR10815:SF14	METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE	BIFUNCTIONAL TRANSCRIPTIONAL ACTIVATOR_DNA REPAIR ENZYME ADA				DNA methyltransferase#PC00013;DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b2888|UniProtKB=Q46821	Q46821	uacT	PTHR42810:SF4	PURINE PERMEASE C1399.01C-RELATED	URIC ACID TRANSPORTER UACT	nucleobase transmembrane transporter activity#GO:0015205;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	localization#GO:0051179;establishment of localization#GO:0051234;nucleobase transport#GO:0015851;nitrogen compound transport#GO:0071705;transport#GO:0006810	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b2241|UniProtKB=P0A9C0	P0A9C0	glpA	PTHR11985:SF36	GLYCEROL-3-PHOSPHATE DEHYDROGENASE	ANAEROBIC GLYCEROL-3-PHOSPHATE DEHYDROGENASE SUBUNIT A				dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b4287|UniProtKB=P15031	P15031	fecE	PTHR42771:SF12	IRON(3+)-HYDROXAMATE IMPORT ATP-BINDING PROTEIN FHUC	FE(3+) DICITRATE TRANSPORT ATP-BINDING PROTEIN FECE-RELATED	siderophore-iron transmembrane transporter activity#GO:0015343;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	chemical homeostasis#GO:0048878;iron coordination entity transport#GO:1901678;response to iron ion#GO:0010039;import into cell#GO:0098657;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;monoatomic ion homeostasis#GO:0050801;response to chemical#GO:0042221;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;iron ion transport#GO:0006826;cellular response to chemical stimulus#GO:0070887;monoatomic ion transport#GO:0006811;siderophore-dependent iron import pathway#GO:0180060;cellular localization#GO:0051641;intracellular monoatomic ion homeostasis#GO:0006873;iron import into cell#GO:0033212;intracellular iron ion homeostasis#GO:0006879;response to stimulus#GO:0050896;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;response to metal ion#GO:0010038;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;siderophore-iron import into cell#GO:0033214;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular response to stimulus#GO:0051716;homeostatic process#GO:0042592;metal ion transport#GO:0030001	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b4269|UniProtKB=P27250	P27250	ahr	PTHR42683:SF38	ALDEHYDE REDUCTASE	ALDEHYDE REDUCTASE AHR	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3190|UniProtKB=P0A9W6	P0A9W6	ibaG	PTHR46229:SF4	BOLA TRANSCRIPTION REGULATOR	ACID STRESS PROTEIN IBAG					
ECOLI|EnsemblGenome=b3298|UniProtKB=P0A7S9	P0A7S9	rpsM	PTHR10871:SF52	30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18	SMALL RIBOSOMAL SUBUNIT PROTEIN US13	structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198		small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226	ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b1325|UniProtKB=P51981	P51981	ycjG	PTHR48080:SF3	D-GALACTONATE DEHYDRATASE-RELATED	ENOLASE SUPERFAMILY MEMBER DDB_G0284701	isomerase activity#GO:0016853;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854	metabolic process#GO:0008152;cellular process#GO:0009987;peptide metabolic process#GO:0006518		dehydratase#PC00091	
ECOLI|EnsemblGenome=b0796|UniProtKB=P0ACU0	P0ACU0	cecR	PTHR30055:SF146	HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR	HTH-TYPE TRANSCRIPTIONAL DUAL REGULATOR CECR	DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252		Tet repressor-like transcription factor#PC00266	
ECOLI|EnsemblGenome=b1813|UniProtKB=P43337	P43337	nudL	PTHR12992:SF47	NUDIX HYDROLASE	NUDIX HYDROLASE DR_1184	hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817			phosphatase#PC00181;hydrolase#PC00121	
ECOLI|EnsemblGenome=b0065|UniProtKB=P30149	P30149	yabI	PTHR30353:SF15	INNER MEMBRANE PROTEIN DEDA-RELATED	INNER MEMBRANE PROTEIN YABI	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cytokinesis#GO:0000910;FtsZ-dependent cytokinesis#GO:0043093;transport#GO:0006810;reproductive process in single-celled organism#GO:0022413;reproductive process#GO:0022414;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;cell division#GO:0051301	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b4189|UniProtKB=P39297	P39297	bsmA	PTHR34156:SF11	OUTER MEMBRANE PROTEIN-RELATED-RELATED	LIPOPROTEIN BSMA		response to stimulus#GO:0050896;response to stress#GO:0006950			
ECOLI|EnsemblGenome=b3959|UniProtKB=P0A6C8	P0A6C8	argB	PTHR23342:SF25	N-ACETYLGLUTAMATE SYNTHASE	ACETYLGLUTAMATE KINASE, CHLOROPLASTIC	catalytic activity#GO:0003824;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772	proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;L-arginine biosynthetic process#GO:0006526;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283			Arginine biosynthesis#P02728>N-acetylglutamate synthase#P02848
ECOLI|EnsemblGenome=b3612|UniProtKB=P37689	P37689	gpmI	PTHR31637:SF16	2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE	2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE	binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;intramolecular transferase activity#GO:0016866;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;catalytic activity#GO:0003824;intramolecular phosphotransferase activity#GO:0016868;isomerase activity#GO:0016853;phosphoglycerate mutase activity#GO:0004619	primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	mutase#PC00160;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3966|UniProtKB=P06129	P06129	btuB	PTHR30069:SF60	TONB-DEPENDENT OUTER MEMBRANE RECEPTOR	VITAMIN B12 TRANSPORTER BTUB	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;siderophore-iron transmembrane transporter activity#GO:0015343	monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;iron coordination entity transport#GO:1901678;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;transport#GO:0006810;metal ion transport#GO:0030001	membrane#GO:0016020;cell outer membrane#GO:0009279;external encapsulating structure#GO:0030312;outer membrane#GO:0019867;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313		
ECOLI|EnsemblGenome=b1448|UniProtKB=P76112	P76112	mnaT	PTHR43072:SF23	N-ACETYLTRANSFERASE	UPF0039 PROTEIN C11D3.02C	acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746			acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0009|UniProtKB=P0AF03	P0AF03	mog	PTHR43764:SF1	MOLYBDENUM COFACTOR BIOSYNTHESIS	MOLYBDOPTERIN MOLYBDOTRANSFERASE	nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772	organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cellular process#GO:0009987;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		
ECOLI|EnsemblGenome=b0655|UniProtKB=P37902	P37902	gltI	PTHR30085:SF2	AMINO ACID ABC TRANSPORTER PERMEASE	GLUTAMATE_ASPARTATE IMPORT SOLUTE-BINDING PROTEIN		transport#GO:0006810;amino acid transport#GO:0006865;localization#GO:0051179;establishment of localization#GO:0051234	cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;extracellular region#GO:0005576;periplasmic space#GO:0042597	primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b3877|UniProtKB=P32137	P32137	yihP	PTHR11328:SF39	MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN	2,3-DIHYDROXYPROPANE-1-SULFONATE EXPORTER-RELATED		transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	primary active transporter#PC00068	
ECOLI|EnsemblGenome=b4225|UniProtKB=P33647	P33647	chpB	PTHR33988:SF3	ENDORIBONUCLEASE MAZF-RELATED	ENDORIBONUCLEASE TOXIN CHPB-RELATED	catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098	RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890		endoribonuclease#PC00094	
ECOLI|EnsemblGenome=b2150|UniProtKB=P0AEE5	P0AEE5	mglB	PTHR30036:SF2	D-XYLOSE-BINDING PERIPLASMIC PROTEIN	D-GALACTOSE_METHYL-GALACTOSIDE BINDING PERIPLASMIC PROTEIN MGLB	carbohydrate binding#GO:0030246;binding#GO:0005488		periplasmic space#GO:0042597;extracellular region#GO:0005576;cell envelope#GO:0030313;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b3132|UniProtKB=P0C8K0	P0C8K0	kbaZ	PTHR32502:SF2	N-ACETYLGALACTOSAMINE PERMEASE II COMPONENT-RELATED	D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE SUBUNIT KBAZ	enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047	transport#GO:0006810;carbohydrate transport#GO:0008643;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;import into cell#GO:0098657;localization#GO:0051179;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b2484|UniProtKB=P77416	P77416	hyfD	PTHR42829:SF2	NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5	NAD(P)H-QUINONE OXIDOREDUCTASE SUBUNIT 5, CHLOROPLASTIC		transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655		oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1012|UniProtKB=P75898	P75898	rutA	PTHR42847:SF4	ALKANESULFONATE MONOOXYGENASE	ALKANESULFONATE MONOOXYGENASE-RELATED	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491	catabolic process#GO:0009056;sulfur compound catabolic process#GO:0044273;cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790		oxygenase#PC00177	
ECOLI|Gene_OrderedLocusName=b4524|UniProtKB=P77481	P77481	ycjV	PTHR43875:SF1	MALTODEXTRIN IMPORT ATP-BINDING PROTEIN MSMX	MALTOSE IMPORT ATP-BINDING PROTEIN YCJV	active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657		membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;ATP-binding cassette (ABC) transporter complex#GO:0043190;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;ATPase dependent transmembrane transport complex#GO:0098533	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227	
ECOLI|EnsemblGenome=b4261|UniProtKB=P0AF98	P0AF98	lptF	PTHR33529:SF7	SLR0882 PROTEIN-RELATED	LIPOPOLYSACCHARIDE EXPORT SYSTEM PERMEASE PROTEIN LPTF		carbohydrate derivative transport#GO:1901264;transport#GO:0006810;macromolecule localization#GO:0033036;lipid localization#GO:0010876;localization#GO:0051179;lipid transport#GO:0006869;establishment of localization#GO:0051234	ATPase dependent transmembrane transport complex#GO:0098533;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;ATP-binding cassette (ABC) transporter complex#GO:0043190;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b3314|UniProtKB=P0A7V3	P0A7V3	rpsC	PTHR11760:SF19	30S/40S RIBOSOMAL PROTEIN S3	SMALL RIBOSOMAL SUBUNIT PROTEIN US3	structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198		ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737	ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b1099|UniProtKB=P28631	P28631	holB	PTHR11669:SF74	REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT	DNA POLYMERASE III SUBUNIT DELTA'		DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139	transferase complex#GO:1990234;catalytic complex#GO:1902494;DNA polymerase complex#GO:0042575;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991	DNA-directed DNA polymerase#PC00018	
ECOLI|EnsemblGenome=b3142|UniProtKB=P42913	P42913	yraH	PTHR33420:SF26	FIMBRIAL SUBUNIT ELFA-RELATED	MANNOSE-RESISTANT_PROTEUS-LIKE FIMBRIAL PROTEIN		single-species biofilm formation#GO:0044010;cell adhesion#GO:0007155;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589	cell projection#GO:0042995;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0577|UniProtKB=P0AAT4	P0AAT4	ybdG	PTHR30414:SF0	MINICONDUCTANCE MECHANOSENSITIVE CHANNEL YBDG	MECHANOSENSING SYSTEM COMPONENT YBDG	channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;gated channel activity#GO:0022836;passive transmembrane transporter activity#GO:0022803	response to abiotic stimulus#GO:0009628;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to environmental stimulus#GO:0104004;cellular response to chemical stimulus#GO:0070887;cellular response to osmotic stress#GO:0071470;response to osmotic stress#GO:0006970;cellular response to stress#GO:0033554;cellular response to chemical stress#GO:0062197;cellular response to abiotic stimulus#GO:0071214	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b3066|UniProtKB=P0ABS5	P0ABS5	dnaG	PTHR30313:SF2	DNA PRIMASE	DNA PRIMASE		RNA metabolic process#GO:0016070;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260;macromolecule biosynthetic process#GO:0009059	DNA helicase complex#GO:0033202;chromosome#GO:0005694;replisome#GO:0030894;replication fork#GO:0005657;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622	primase#PC00189	
ECOLI|EnsemblGenome=b4042|UniProtKB=P0ABN1	P0ABN1	dgkA	PTHR34299:SF1	DIACYLGLYCEROL KINASE	DIACYLGLYCEROL KINASE	lipid kinase activity#GO:0001727;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	metabolite interconversion enzyme#PC00262;kinase#PC00137	
ECOLI|EnsemblGenome=b4296|UniProtKB=P39357	P39357	yjhF	PTHR30354:SF22	GNT FAMILY GLUCONATE TRANSPORTER	HIGH-AFFINITY GLUCONATE TRANSPORTER	carbohydrate transmembrane transporter activity#GO:0015144;monocarboxylic acid transmembrane transporter activity#GO:0008028;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857	carbohydrate transport#GO:0008643;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;carboxylic acid transmembrane transport#GO:1905039	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227;secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b0199|UniProtKB=P30750	P30750	metN	PTHR43166:SF30	AMINO ACID IMPORT ATP-BINDING PROTEIN	METHIONINE IMPORT ATP-BINDING PROTEIN METN	ATPase-coupled transmembrane transporter activity#GO:0042626;carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;amino acid transport#GO:0006865;localization#GO:0051179;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227;primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0845|UniProtKB=P75810	P75810	ybjJ	PTHR23514:SF13	BYPASS OF STOP CODON PROTEIN 6	INNER MEMBRANE PROTEIN YBJJ			cellular anatomical structure#GO:0110165;membrane#GO:0016020		
ECOLI|EnsemblGenome=b2923|UniProtKB=P11667	P11667	argO	PTHR30086:SF23	ARGININE EXPORTER PROTEIN ARGO	ARGININE EXPORTER PROTEIN ARGO	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171	transport#GO:0006810;amino acid transport#GO:0006865;localization#GO:0051179;establishment of localization#GO:0051234	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|Gene_OrderedLocusName=b4285|UniProtKB=Q47718	Q47718	insO2	PTHR46889:SF8	TRANSPOSASE INSF FOR INSERTION SEQUENCE IS3B-RELATED	TRANSPOSASE INSO FOR INSERTION SEQUENCE ELEMENT IS911A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b1983|UniProtKB=P0A8A2	P0A8A2	yeeN	PTHR12532:SF0	TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1	TRANSCRIPTIONAL REGULATORY PROTEIN YEEN-RELATED		post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of translation#GO:0045727;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794			
ECOLI|EnsemblGenome=b3229|UniProtKB=P0ACA3	P0ACA3	sspA	PTHR43968:SF17	FAMILY NOT NAMED	STRINGENT STARVATION PROTEIN A			cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b0190|UniProtKB=P0AA97	P0AA97	yaeQ	PTHR38784:SF1	SUCROSE PHOSPHORYLASE	YAEQ FAMILY PROTEIN					
ECOLI|EnsemblGenome=b1277|UniProtKB=P0A7I7	P0A7I7	ribA	PTHR21327:SF49	GTP CYCLOHYDROLASE II-RELATED	GTP CYCLOHYDROLASE-2	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity#GO:0016787;lyase activity#GO:0016829;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824	small molecule metabolic process#GO:0044281;flavin-containing compound metabolic process#GO:0042726;biosynthetic process#GO:0009058;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;cellular process#GO:0009987	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	hydrolase#PC00121	Flavin biosynthesis#P02741>GTP cyclohydrolase#P02935
ECOLI|EnsemblGenome=b0120|UniProtKB=P0A7F6	P0A7F6	speD	PTHR33866:SF1	S-ADENOSYLMETHIONINE DECARBOXYLASE PROENZYME	S-ADENOSYLMETHIONINE DECARBOXYLASE PROENZYME	lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824	polyamine biosynthetic process#GO:0006596;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;amine metabolic process#GO:0009308;metabolic process#GO:0008152;cellular process#GO:0009987;polyamine metabolic process#GO:0006595	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	decarboxylase#PC00089;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0391|UniProtKB=P0C037	P0C037	ppnP	PTHR36540:SF1	PYRIMIDINE/PURINE NUCLEOSIDE PHOSPHORYLASE	PYRIMIDINE_PURINE NUCLEOSIDE PHOSPHORYLASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757		cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b0813|UniProtKB=P0AA67	P0AA67	rhtA	PTHR22911:SF37	ACYL-MALONYL CONDENSING ENZYME-RELATED	THREONINE_HOMOSERINE EXPORTER RHTA	neutral L-amino acid transmembrane transporter activity#GO:0015175;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179;efflux transmembrane transporter activity#GO:0015562		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b3191|UniProtKB=P64602	P64602	mlaB	PTHR35849:SF1	BLR2341 PROTEIN	INTERMEMBRANE PHOSPHOLIPID TRANSPORT SYSTEM BINDING PROTEIN MLAB	lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319	intermembrane phospholipid transfer#GO:0120010;membrane organization#GO:0061024;phospholipid transport#GO:0015914;lipid transport#GO:0006869;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;intermembrane lipid transfer#GO:0120009;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;DNA damage response#GO:0006974;response to stimulus#GO:0050896;organophosphate ester transport#GO:0015748;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;localization#GO:0051179;cellular response to stress#GO:0033554;lipid localization#GO:0010876	protein-containing complex#GO:0032991;transporter complex#GO:1990351		
ECOLI|EnsemblGenome=b0948|UniProtKB=P75864	P75864	rlmL	PTHR47313:SF1	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L	S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a rRNA#GO:0140102;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;rRNA (guanine) methyltransferase activity#GO:0016435			RNA processing factor#PC00147;RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b2218|UniProtKB=P0DMC5	P0DMC5	rcsC	PTHR43711:SF26	TWO-COMPONENT HISTIDINE KINASE	SENSOR HISTIDINE KINASE RCSC	protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;protein histidine kinase activity#GO:0004673;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphorelay sensor kinase activity#GO:0000155;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775	intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;phosphorelay signal transduction system#GO:0000160	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	histidine kinase receptor of two-component system#PC00265;transmembrane signal receptor#PC00197	
ECOLI|EnsemblGenome=b2957|UniProtKB=P00805	P00805	ansB	PTHR43828:SF17	ASPARAGINASE	L-ASPARAGINASE 2	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;amidase activity#GO:0004040;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787	oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520		hydrolase#PC00121	
ECOLI|EnsemblGenome=b0042|UniProtKB=P31574	P31574	fixB	PTHR43153:SF5	ELECTRON TRANSFER FLAVOPROTEIN ALPHA	PROTEIN FIXB-RELATED	heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660	lipid modification#GO:0030258;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787		oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3711|UniProtKB=P31463	P31463	yidZ	PTHR30118:SF11	HTH-TYPE TRANSCRIPTIONAL REGULATOR LEUO-RELATED	HTH-TYPE TRANSCRIPTIONAL REGULATOR YIDZ	transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468	protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991	helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b3738|UniProtKB=P0AB98	P0AB98	atpB	PTHR42823:SF5	ATP SYNTHASE SUBUNIT A, CHLOROPLASTIC	ATP SYNTHASE SUBUNIT A	proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton channel activity#GO:0015252;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803	ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;organophosphate biosynthetic process#GO:0090407;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;ATP biosynthetic process#GO:0006754;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165	membrane protein complex#GO:0098796;membrane#GO:0016020;respiratory chain complex#GO:0098803;cell periphery#GO:0071944;proton-transporting ATP synthase complex#GO:0045259;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;catalytic complex#GO:1902494;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351	ATP synthase#PC00002	
ECOLI|Gene_OrderedLocusName=JW5170|UniProtKB=P75981	P75981	jayE	PTHR37829:SF3	PHAGE-LIKE ELEMENT PBSX PROTEIN XKDT	PROTEIN JAYE-RELATED					
ECOLI|EnsemblGenome=b0779|UniProtKB=P0A8F8	P0A8F8	uvrB	PTHR24029:SF0	UVRABC SYSTEM PROTEIN B	UVRABC SYSTEM PROTEIN B		response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259	catalytic complex#GO:1902494;DNA repair complex#GO:1990391;endonuclease complex#GO:1905348;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991	DNA metabolism protein#PC00009;exodeoxyribonuclease#PC00098	
ECOLI|EnsemblGenome=b1302|UniProtKB=P50457	P50457	puuE	PTHR43206:SF3	AMINOTRANSFERASE	4-AMINOBUTYRATE AMINOTRANSFERASE PUUE	ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;heterocyclic compound binding#GO:1901363	carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	transferase#PC00220;transaminase#PC00216;metabolite interconversion enzyme#PC00262	Aminobutyrate degradation#P02726>4-aminobutyrate aminotransferase#P02825
ECOLI|EnsemblGenome=b4463|UniProtKB=Q46911	Q46911	ygcU	PTHR11748:SF122	D-LACTATE DEHYDROGENASE	ARYL-ALCOHOL OXIDASE VANILLYL-ALCOHOL OXIDASE (AFU_ORTHOLOGUE AFUA_3G09500)-RELATED	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614	oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752		dehydrogenase#PC00092;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3312|UniProtKB=P0A7M6	P0A7M6	rpmC	PTHR10916:SF0	60S RIBOSOMAL PROTEIN L35/50S RIBOSOMAL PROTEIN L29	LARGE RIBOSOMAL SUBUNIT PROTEIN UL29	structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198		intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991	translational protein#PC00263;ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b4365|UniProtKB=P0ADD7	P0ADD7	yjjQ	PTHR43214:SF30	TWO-COMPONENT RESPONSE REGULATOR	TRANSCRIPTION FACTOR YJJQ-RELATED	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007		helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b2029|UniProtKB=P00350	P00350	gnd	PTHR11811:SF25	6-PHOSPHOGLUCONATE DEHYDROGENASE	6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING	nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824;purine nucleotide binding#GO:0017076;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;phosphogluconate dehydrogenase (decarboxylating) activity#GO:0004616;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;binding#GO:0005488;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265	nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;pentose-phosphate shunt, oxidative branch#GO:0009051;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;pentose-phosphate shunt#GO:0006098;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	dehydrogenase#PC00092	Pentose phosphate pathway#P02762>Gluconate Dehydrogenase#P03070
ECOLI|EnsemblGenome=b1875|UniProtKB=P52007	P52007	yecM	PTHR37519:SF1	FAMILY NOT NAMED	PROTEIN YECM			cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b0169|UniProtKB=P0A7V0	P0A7V0	rpsB	PTHR12534:SF2	30S RIBOSOMAL PROTEIN S2  PROKARYOTIC AND ORGANELLAR	SMALL RIBOSOMAL SUBUNIT PROTEIN US2	structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735			ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b2370|UniProtKB=P30855	P30855	evgS	PTHR43719:SF28	TWO-COMPONENT HISTIDINE KINASE	PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK1-RELATED	phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphorelay sensor kinase activity#GO:0000155;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein histidine kinase activity#GO:0004673;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299	signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;phosphorelay signal transduction system#GO:0000160;intracellular signal transduction#GO:0035556;cell communication#GO:0007154	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	histidine kinase receptor of two-component system#PC00265;transmembrane signal receptor#PC00197	
ECOLI|EnsemblGenome=b3836|UniProtKB=P69428	P69428	tatA	PTHR42982:SF1	SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATA	SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATA	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transmembrane protein transporter activity#GO:0008320	intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;protein transmembrane transport#GO:0071806;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b2787|UniProtKB=P0AES2	P0AES2	gudD	PTHR48080:SF4	D-GALACTONATE DEHYDRATASE-RELATED	GLUCARATE DEHYDRATASE	catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835	carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436		dehydratase#PC00091	
ECOLI|EnsemblGenome=b1062|UniProtKB=P05020	P05020	pyrC	PTHR43137:SF1	DIHYDROOROTASE	DIHYDROOROTASE	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812	nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;pyrimidine nucleobase metabolic process#GO:0006206;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753		hydrolase#PC00121;metabolite interconversion enzyme#PC00262	De novo pyrimidine ribonucleotides biosythesis#P02740>Dihydroorotase#P02928
ECOLI|EnsemblGenome=b1765|UniProtKB=P0ACY1	P0ACY1	ydjA	PTHR43821:SF1	NAD(P)H NITROREDUCTASE YDJA-RELATED	NAD(P)H NITROREDUCTASE YDJA-RELATED			cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	reductase#PC00198;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3518|UniProtKB=P37197	P37197	ccp	PTHR30600:SF7	CYTOCHROME C PEROXIDASE-RELATED	CYTOCHROME C PEROXIDASE CCP	catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491	anaerobic electron transport chain#GO:0019645;hydrogen peroxide metabolic process#GO:0042743;anaerobic respiration#GO:0009061;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593		oxidoreductase#PC00176;peroxidase#PC00180	
ECOLI|EnsemblGenome=b0763|UniProtKB=P37329	P37329	modA	PTHR30632:SF17	MOLYBDATE-BINDING PERIPLASMIC PROTEIN	MOLYBDATE-BINDING PROTEIN MODA	small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167	transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;inorganic anion transport#GO:0015698	periplasmic space#GO:0042597;extracellular region#GO:0005576;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313		
ECOLI|EnsemblGenome=b1503|UniProtKB=P77294	P77294	ydeR	PTHR33420:SF27	FIMBRIAL SUBUNIT ELFA-RELATED	PROTEIN FIMG		single-species biofilm formation#GO:0044010;cell adhesion#GO:0007155;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589	cellular anatomical structure#GO:0110165;cell projection#GO:0042995		
ECOLI|EnsemblGenome=b2841|UniProtKB=P0AE24	P0AE24	araE	PTHR48023:SF10	D-XYLOSE-PROTON SYMPORTER-LIKE 2	ARABINOSE-PROTON SYMPORTER				transporter#PC00227;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b2562|UniProtKB=P52102	P52102	yfhL	PTHR24960:SF88	PHOTOSYSTEM I IRON-SULFUR CENTER-RELATED	FERREDOXIN YFHL			cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b3718|UniProtKB=P31470	P31470	yieK	PTHR11280:SF5	GLUCOSAMINE-6-PHOSPHATE ISOMERASE	GLUCOSAMINE-6-PHOSPHATE DEAMINASE	binding#GO:0005488;catalytic activity#GO:0003824;deaminase activity#GO:0019239;identical protein binding#GO:0042802;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;protein binding#GO:0005515;hydrolase activity#GO:0016787	amino sugar catabolic process#GO:0046348;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	isomerase#PC00135	N-acetylglucosamine metabolism#P02756>Glucosamine-6-phosphate deaminase#P03041
ECOLI|EnsemblGenome=b3011|UniProtKB=Q46856	Q46856	yqhD	PTHR43633:SF2	ALCOHOL DEHYDROGENASE YQHD	NADPH-DEPENDENT ALDEHYDE REDUCTASE YQHD	alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491		cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b2013|UniProtKB=P33015	P33015	tsuA	PTHR30574:SF1	INNER MEMBRANE PROTEIN YEDE	THIOSULFATE TRANSPORTER TSUA-RELATED			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b1885|UniProtKB=P07018	P07018	tap	PTHR43531:SF14	PROTEIN ICFG	METHYL-ACCEPTING CHEMOTAXIS PROTEIN I-RELATED	molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888	chemotaxis#GO:0006935;taxis#GO:0042330;response to chemical#GO:0042221;response to stimulus#GO:0050896;locomotion#GO:0040011;response to external stimulus#GO:0009605	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b1663|UniProtKB=P37340	P37340	mdtK	PTHR11206:SF283	MULTIDRUG RESISTANCE PROTEIN	MULTIDRUG RESISTANCE PROTEIN MDTK	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;xenobiotic transmembrane transporter activity#GO:0042910	response to stimulus#GO:0050896;response to chemical#GO:0042221;response to antibiotic#GO:0046677	cellular anatomical structure#GO:0110165;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b2266|UniProtKB=P0AEH5	P0AEH5	elaB	PTHR35893:SF1	INNER MEMBRANE PROTEIN-RELATED	PROTEIN ELAB		cellular response to stress#GO:0033554;DNA damage response#GO:0006974;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to stimulus#GO:0050896	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b1259|UniProtKB=P21361	P21361	yciG	PTHR36569:SF5	FAMILY NOT NAMED	CONIDIATION-SPECIFIC PROTEIN 10 (EUROFUNG)					
ECOLI|EnsemblGenome=b0570|UniProtKB=P77485	P77485	cusS	PTHR45436:SF5	SENSOR HISTIDINE KINASE YKOH	SENSOR HISTIDINE KINASE CUSS				transmembrane signal receptor#PC00197;histidine kinase receptor of two-component system#PC00265	
ECOLI|EnsemblGenome=b2130|UniProtKB=P33361	P33361	yehY	PTHR30177:SF30	GLYCINE BETAINE/L-PROLINE TRANSPORT SYSTEM PERMEASE PROTEIN PROW	GLYCINE BETAINE UPTAKE SYSTEM PERMEASE PROTEIN YEHY		establishment of localization#GO:0051234;localization#GO:0051179;nitrogen compound transport#GO:0071705;quaternary ammonium group transport#GO:0015697;transport#GO:0006810			
ECOLI|EnsemblGenome=b0876|UniProtKB=P75828	P75828	ybjD	PTHR32182:SF19	DNA REPLICATION AND REPAIR PROTEIN RECF	OLD PROTEIN-LIKE TOPRIM DOMAIN-CONTAINING PROTEIN		DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA repair#GO:0006281;metabolic process#GO:0008152;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;recombinational repair#GO:0000725;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896		DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b4381|UniProtKB=P0A6L0	P0A6L0	deoC	PTHR10889:SF3	DEOXYRIBOSE-PHOSPHATE ALDOLASE	DEOXYRIBOSE-PHOSPHATE ALDOLASE	carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829	primary metabolic process#GO:0044238;glycosyl compound catabolic process#GO:1901658;nucleobase-containing small molecule catabolic process#GO:0034656;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleoside catabolic process#GO:0009164;nucleobase-containing small molecule metabolic process#GO:0055086		aldolase#PC00044;lyase#PC00144	
ECOLI|EnsemblGenome=b0084|UniProtKB=P0AD68	P0AD68	ftsI	PTHR30627:SF1	PEPTIDOGLYCAN D,D-TRANSPEPTIDASE	PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI	carboxylic acid binding#GO:0031406;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;organic acid binding#GO:0043177;heterocyclic compound binding#GO:1901363	cellular process#GO:0009987;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;cell wall organization#GO:0071555;cell wall organization or biogenesis#GO:0071554	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	hydrolase#PC00121	
ECOLI|EnsemblGenome=b3447|UniProtKB=P18956	P18956	ggt	PTHR43199:SF1	GLUTATHIONE HYDROLASE	GLUTATHIONE HYDROLASE PROENZYME	hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824			protease#PC00190	
ECOLI|EnsemblGenome=b1262|UniProtKB=P00909	P00909	trpC	PTHR22854:SF2	TRYPTOPHAN BIOSYNTHESIS PROTEIN	INDOLE-3-GLYCEROL-PHOSPHATE SYNTHASE	carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;lyase activity#GO:0016829	amine metabolic process#GO:0009308;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;aromatic amino acid biosynthetic process#GO:0009073;indole-containing compound metabolic process#GO:0042430;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436		isomerase#PC00135	Tryptophan biosynthesis#P02783>Indole-3-glycerol phosphate synthase#P03210
ECOLI|EnsemblGenome=b0130|UniProtKB=P31666	P31666	yadE	PTHR34216:SF13	POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE N-DEACETYLASE-RELATED	POLYSACCHARIDE DEACETYLASE YADE-RELATED	catalytic activity#GO:0003824;hydrolase activity#GO:0016787				
ECOLI|EnsemblGenome=b1768|UniProtKB=P21369	P21369	pncA	PTHR11080:SF2	PYRAZINAMIDASE/NICOTINAMIDASE	NICOTINAMIDASE	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;amidase activity#GO:0004040;catalytic activity#GO:0003824				
ECOLI|EnsemblGenome=b3328|UniProtKB=P41442	P41442	gspG	PTHR30093:SF48	GENERAL SECRETION PATHWAY PROTEIN G	TYPE II SECRETION SYSTEM CORE PROTEIN G		establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;protein secretion by the type II secretion system#GO:0015628;establishment of localization#GO:0051234;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;secretion by cell#GO:0032940;protein transport#GO:0015031;localization#GO:0051179;protein secretion#GO:0009306;transmembrane transport#GO:0055085;secretion#GO:0046903	type II protein secretion system complex#GO:0015627;protein-containing complex#GO:0032991		
ECOLI|EnsemblGenome=b3783|UniProtKB=P0AG30	P0AG30	rho	PTHR46425:SF1	TRANSCRIPTION TERMINATION FACTOR RHO	TRANSCRIPTION TERMINATION FACTOR RHO		nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription termination#GO:0006353;gene expression#GO:0010467;DNA-templated transcription#GO:0006351;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058			
ECOLI|EnsemblGenome=b1942|UniProtKB=P52613	P52613	fliJ	PTHR38786:SF1	FLAGELLAR FLIJ PROTEIN	FLAGELLAR FLIJ PROTEIN				structural protein#PC00211	
ECOLI|EnsemblGenome=b1033|UniProtKB=P75913	P75913	ghrA	PTHR10996:SF114	2-HYDROXYACID DEHYDROGENASE-RELATED	GLYOXYLATE_HYDROXYPYRUVATE REDUCTASE A	catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614		cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b3255|UniProtKB=P0ABD8	P0ABD8	accB	PTHR43416:SF38	DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED	BIOTIN CARBOXYL CARRIER PROTEIN OF ACETYL-COA CARBOXYLASE	catalytic activity#GO:0003824;ligase activity#GO:0016874	oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058		transferase#PC00220	
ECOLI|EnsemblGenome=b3834|UniProtKB=P0ADP7	P0ADP7	ubiJ	PTHR38693:SF1	UBIQUINONE BIOSYNTHESIS PROTEIN UBIJ	UBIQUINONE BIOSYNTHESIS ACCESSORY FACTOR UBIJ		small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;ubiquinone biosynthetic process#GO:0006744;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ketone metabolic process#GO:0042180;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281			
ECOLI|EnsemblGenome=b4467|UniProtKB=P52074	P52074	glcF	PTHR32479:SF17	GLYCOLATE OXIDASE IRON-SULFUR SUBUNIT	GLYCOLATE OXIDASE IRON-SULFUR SUBUNIT	catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;alcohol metabolic process#GO:0006066;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid catabolic process#GO:0072329;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2133|UniProtKB=P06149	P06149	dld	PTHR43716:SF4	D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL	QUINONE-DEPENDENT D-LACTATE DEHYDROGENASE	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614	generation of precursor metabolites and energy#GO:0006091;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;metabolic process#GO:0008152;electron transport chain#GO:0022900;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333	cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562	dehydrogenase#PC00092;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0831|UniProtKB=P75798	P75798	gsiC	PTHR43163:SF5	DIPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN DPPB-RELATED	GLUTATHIONE TRANSPORT SYSTEM PERMEASE PROTEIN GSIC	oligopeptide transmembrane transporter activity#GO:0035673;transporter activity#GO:0005215;tripeptide transmembrane transporter activity#GO:0042937;transmembrane transporter activity#GO:0022857		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b3143|UniProtKB=P42914	P42914	yraI	PTHR30251:SF11	PILUS ASSEMBLY CHAPERONE	CHAPERONE PROTEIN FIMC-RELATED		metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604	extracellular region#GO:0005576;periplasmic space#GO:0042597;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313	chaperone#PC00072	
ECOLI|EnsemblGenome=b1027|UniProtKB=P0CF69	P0CF69	insE4	PTHR33215:SF6	PROTEIN DISTAL ANTENNA	TRANSPOSASE INSE FOR INSERTION SEQUENCE IS3A-RELATED					
ECOLI|EnsemblGenome=b2051|UniProtKB=P32056	P32056	gmm	PTHR43046:SF12	GDP-MANNOSE MANNOSYL HYDROLASE	GDP-MANNOSE MANNOSYL HYDROLASE	catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787			hydrolase#PC00121;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0842|UniProtKB=P0AEY8	P0AEY8	mdfA	PTHR23502:SF43	MAJOR FACILITATOR SUPERFAMILY	MULTIDRUG TRANSPORTER MDFA	monoatomic cation transmembrane transporter activity#GO:0008324;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;metal cation:proton antiporter activity#GO:0051139;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078	response to stimulus#GO:0050896;response to chemical#GO:0042221;response to toxic substance#GO:0009636;export from cell#GO:0140352;detoxification#GO:0098754;xenobiotic detoxification by transmembrane export across the plasma membrane#GO:1990961;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;xenobiotic transport#GO:0042908;transport#GO:0006810	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b1750|UniProtKB=P76219	P76219	ydjX	PTHR46826:SF1	FAMILY NOT NAMED	TVP38_TMEM64 FAMILY MEMBRANE PROTEIN YDJX					
ECOLI|EnsemblGenome=b2861|UniProtKB=P0CF43	P0CF43	insC4	PTHR37936:SF3	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b0425|UniProtKB=P0A9J4	P0A9J4	panE	PTHR43765:SF2	2-DEHYDROPANTOATE 2-REDUCTASE-RELATED	2-DEHYDROPANTOATE 2-REDUCTASE	nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;binding#GO:0005488;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265		cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	reductase#PC00198;metabolite interconversion enzyme#PC00262	Pantothenate biosynthesis#P02761>2-Dehydropantoate reductase#P03069
ECOLI|EnsemblGenome=b4538|UniProtKB=Q2EES3	Q2EES3	yoeF	PTHR40453:SF3	PROTEIN YOEF	PROTEIN YOEF			intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229		
ECOLI|EnsemblGenome=b0149|UniProtKB=P02919	P02919	mrcB	PTHR32282:SF11	BINDING PROTEIN TRANSPEPTIDASE, PUTATIVE-RELATED	PENICILLIN-BINDING PROTEIN 1B	catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757	cell wall macromolecule metabolic process#GO:0044036;cell wall biogenesis#GO:0042546;aminoglycan metabolic process#GO:0006022;peptidoglycan biosynthetic process#GO:0009252;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;glycosaminoglycan biosynthetic process#GO:0006024;peptidoglycan-based cell wall biogenesis#GO:0009273;metabolic process#GO:0008152;peptidoglycan metabolic process#GO:0000270;biosynthetic process#GO:0009058;cell wall organization or biogenesis#GO:0071554;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;cell wall macromolecule biosynthetic process#GO:0044038;cellular component biogenesis#GO:0044085	extracellular region#GO:0005576;periplasmic space#GO:0042597;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313		
ECOLI|EnsemblGenome=b3173|UniProtKB=P42640	P42640	yhbX	PTHR30443:SF4	INNER MEMBRANE PROTEIN	PHOSPHOETHANOLAMINE TRANSFERASE OPGE-RELATED	phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824	primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;lipopolysaccharide core region biosynthetic process#GO:0009244;lipopolysaccharide biosynthetic process#GO:0009103;liposaccharide metabolic process#GO:1903509;polysaccharide metabolic process#GO:0005976;polysaccharide biosynthetic process#GO:0000271;lipopolysaccharide metabolic process#GO:0008653;oligosaccharide biosynthetic process#GO:0009312;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oligosaccharide metabolic process#GO:0009311;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b0350|UniProtKB=P77608	P77608	mhpD	PTHR30143:SF0	ACID HYDRATASE	2-KETO-4-PENTENOATE HYDRATASE	catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835		cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;hydratase#PC00120	
ECOLI|EnsemblGenome=b3613|UniProtKB=P37690	P37690	envC	PTHR21666:SF295	PEPTIDASE-RELATED	MUREIN HYDROLASE ACTIVATOR ENVC	hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237	cellular process#GO:0009987;cell division#GO:0051301		metalloprotease#PC00153;protease#PC00190	
ECOLI|EnsemblGenome=b2462|UniProtKB=P63746	P63746	eutS	PTHR40449:SF2	ETHANOLAMINE UTILIZATION PROTEIN EUTS	BACTERIAL MICROCOMPARTMENT SHELL PROTEIN EUTS			intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229		
ECOLI|EnsemblGenome=b3075|UniProtKB=P06846	P06846	ebgR	PTHR30146:SF149	LACI-RELATED TRANSCRIPTIONAL REPRESSOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR EBGR	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219		Lambda repressor-like transcription factor#PC00245;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b2327|UniProtKB=P0AD30	P0AD30	yfcA	PTHR30269:SF0	TRANSMEMBRANE PROTEIN YFCA	MEMBRANE TRANSPORTER PROTEIN YFCA-RELATED					
ECOLI|EnsemblGenome=b2688|UniProtKB=P0A6W9	P0A6W9	gshA	PTHR38761:SF1	GLUTAMATE--CYSTEINE LIGASE	GLUTAMATE--CYSTEINE LIGASE	ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;metal ion binding#GO:0046872;cation binding#GO:0043169;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874	metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;cellular process#GO:0009987;peptide metabolic process#GO:0006518;biosynthetic process#GO:0009058	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	ligase#PC00142	
ECOLI|EnsemblGenome=b0631|UniProtKB=P0A8J4	P0A8J4	ybeD	PTHR38036:SF1	UPF0250 PROTEIN YBED	UPF0250 PROTEIN YBED					
ECOLI|Gene_OrderedLocusName=JW5383|UniProtKB=P77326	P77326	tfaS	PTHR34413:SF2	PROPHAGE TAIL FIBER ASSEMBLY PROTEIN HOMOLOG TFAE-RELATED-RELATED	PROPHAGE TAIL FIBER ASSEMBLY PROTEIN HOMOLOG TFAE-RELATED				chaperone#PC00072	
ECOLI|EnsemblGenome=b3179|UniProtKB=P0C0R7	P0C0R7	rlmE	PTHR10920:SF18	RIBOSOMAL RNA METHYLTRANSFERASE	RRNA METHYLTRANSFERASE 2, MITOCHONDRIAL	catalytic activity, acting on a rRNA#GO:0140102;O-methyltransferase activity#GO:0008171;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741	biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;ribosomal large subunit assembly#GO:0000027;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;organelle assembly#GO:0070925;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;protein-RNA complex organization#GO:0071826;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;ribonucleoprotein complex biogenesis#GO:0022613;rRNA modification#GO:0000154;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;methylation#GO:0032259;RNA metabolic process#GO:0016070;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254		RNA methyltransferase#PC00033	
ECOLI|EnsemblGenome=b1600|UniProtKB=P69212	P69212	mdtJ	PTHR30561:SF2	SMR FAMILY PROTON-DEPENDENT DRUG EFFLUX TRANSPORTER SUGE	SPERMIDINE EXPORT PROTEIN MDTJ	secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804;polyamine transmembrane transporter activity#GO:0015203	detoxification#GO:0098754;export from cell#GO:0140352;response to toxic substance#GO:0009636;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular process#GO:0009987;xenobiotic detoxification by transmembrane export across the plasma membrane#GO:1990961;nitrogen compound transport#GO:0071705;quaternary ammonium group transport#GO:0015697;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;xenobiotic transport#GO:0042908	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b4018|UniProtKB=P16528	P16528	iclR	PTHR30136:SF22	HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY	TRANSCRIPTIONAL REPRESSOR ICLR	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b4000|UniProtKB=P0ACF0	P0ACF0	hupA	PTHR33175:SF12	DNA-BINDING PROTEIN HU	DNA-BINDING PROTEIN HU-ALPHA	DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110	regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090	bacterial nucleoid#GO:0043590;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoid#GO:0009295;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;chromosome#GO:0005694;replisome#GO:0030894;replication fork#GO:0005657	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b1679|UniProtKB=P76194	P76194	sufE	PTHR43597:SF3	SULFUR ACCEPTOR PROTEIN CSDE	CYSTEINE DESULFURATION PROTEIN SUFE	molecular carrier activity#GO:0140104;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234		protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;sulfurtransferase complex#GO:1990228;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234		
ECOLI|EnsemblGenome=b3723|UniProtKB=P11989	P11989	bglG	PTHR30185:SF15	CRYPTIC BETA-GLUCOSIDE BGL OPERON ANTITERMINATOR	CRYPTIC BETA-GLUCOSIDE BGL OPERON ANTITERMINATOR					
ECOLI|EnsemblGenome=b3931|UniProtKB=P0A6H5	P0A6H5	hslU	PTHR48102:SF3	ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED	ATP-DEPENDENT PROTEASE ATPASE SUBUNIT HSLU	ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265	primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538	endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytosol#GO:0005829;proteasome complex#GO:0000502;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;peptidase complex#GO:1905368	protease#PC00190	
ECOLI|EnsemblGenome=b0033|UniProtKB=P00968	P00968	carB	PTHR11405:SF53	CARBAMOYLTRANSFERASE FAMILY MEMBER	MULTIFUNCTIONAL PROTEIN PYR1-3	ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874	oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;ligase#PC00142	Arginine biosynthesis#P02728>Carbamoyl phosphate synthase#P02845;De novo pyrimidine ribonucleotides biosythesis#P02740>Carbamoyl phosphate synthetase#P02925
ECOLI|EnsemblGenome=b0635|UniProtKB=P0AD65	P0AD65	mrdA	PTHR30627:SF2	PEPTIDOGLYCAN D,D-TRANSPEPTIDASE	PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA	organic acid binding#GO:0043177;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;small molecule binding#GO:0036094;serine-type peptidase activity#GO:0008236;binding#GO:0005488;ion binding#GO:0043167;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;heterocyclic compound binding#GO:1901363	cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell wall organization or biogenesis#GO:0071554;cell wall organization#GO:0071555;external encapsulating structure organization#GO:0045229	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	hydrolase#PC00121	
ECOLI|EnsemblGenome=b3153|UniProtKB=P45470	P45470	yhbO	PTHR42733:SF2	DJ-1 PROTEIN	DJ-1_THIJ_PFPI FAMILY PROTEIN	carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824	cellular response to stimulus#GO:0051716;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170		protein modifying enzyme#PC00260;cysteine protease#PC00081	
ECOLI|EnsemblGenome=b4162|UniProtKB=P0A784	P0A784	orn	PTHR11046:SF30	OLIGORIBONUCLEASE, MITOCHONDRIAL	OLIGORIBONUCLEASE				endoribonuclease#PC00094;RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b4111|UniProtKB=P0C0L7	P0C0L7	proP	PTHR43528:SF5	ALPHA-KETOGLUTARATE PERMEASE	PROLINE_BETAINE TRANSPORTER	monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	import into cell#GO:0098657;cellular response to abiotic stimulus#GO:0071214;cellular response to chemical stress#GO:0062197;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;transmembrane transport#GO:0055085;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;import across plasma membrane#GO:0098739;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;establishment of localization#GO:0051234;transport#GO:0006810;response to osmotic stress#GO:0006970;biological regulation#GO:0065007;nitrogen compound transport#GO:0071705;intracellular signal transduction#GO:0035556;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;cell communication#GO:0007154;cellular response to osmotic stress#GO:0071470;carboxylic acid transmembrane transport#GO:1905039;regulation of cellular process#GO:0050794;cellular response to environmental stimulus#GO:0104004;cellular response to stimulus#GO:0051716;osmosensory signaling pathway#GO:0007231	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b1391|UniProtKB=P76080	P76080	paaD	PTHR42831:SF3	FE-S PROTEIN MATURATION AUXILIARY FACTOR YITW	1,2-PHENYLACETYL-COA EPOXIDASE, SUBUNIT D-RELATED					
ECOLI|EnsemblGenome=b2384|UniProtKB=P77585	P77585	ypdE	PTHR32481:SF0	AMINOPEPTIDASE	AMINOPEPTIDASE YPDE-RELATED	metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096			metalloprotease#PC00153	
ECOLI|EnsemblGenome=b2606|UniProtKB=P0A7K6	P0A7K6	rplS	PTHR15680:SF9	RIBOSOMAL PROTEIN L19	LARGE RIBOSOMAL SUBUNIT PROTEIN BL19	structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735			translational protein#PC00263;ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b4071|UniProtKB=P0ABL1	P0ABL1	nrfB	PTHR35038:SF5	DISSIMILATORY SULFITE REDUCTASE SIRA	CYTOCHROME C-TYPE PROTEIN NRFB	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			reductase#PC00198;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3396|UniProtKB=P02918	P02918	mrcA	PTHR32282:SF27	BINDING PROTEIN TRANSPEPTIDASE, PUTATIVE-RELATED	PENICILLIN-BINDING PROTEIN 1A	catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757	cell wall macromolecule metabolic process#GO:0044036;cell wall biogenesis#GO:0042546;aminoglycan metabolic process#GO:0006022;peptidoglycan biosynthetic process#GO:0009252;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;glycosaminoglycan biosynthetic process#GO:0006024;macromolecule metabolic process#GO:0043170;peptidoglycan-based cell wall biogenesis#GO:0009273;peptidoglycan metabolic process#GO:0000270;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cell wall organization or biogenesis#GO:0071554;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;cell wall macromolecule biosynthetic process#GO:0044038;cellular component biogenesis#GO:0044085	cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;extracellular region#GO:0005576;periplasmic space#GO:0042597		
ECOLI|EnsemblGenome=b2577|UniProtKB=P33634	P33634	yfiE	PTHR30126:SF5	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL ACTIVATOR CMPR	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690	regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468		gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b2111|UniProtKB=P33343	P33343	yehD	PTHR33420:SF32	FIMBRIAL SUBUNIT ELFA-RELATED	FIMBRIAL-LIKE PROTEIN		single-species biofilm formation#GO:0044010;cellular process#GO:0009987;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589	cell projection#GO:0042995;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0884|UniProtKB=P69222	P69222	infA	PTHR33370:SF7	TRANSLATION INITIATION FACTOR IF-1, CHLOROPLASTIC	TRANSLATION INITIATION FACTOR IF-1	molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-RNA adaptor activity#GO:0140517	macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223	
ECOLI|EnsemblGenome=b0207|UniProtKB=P30863	P30863	dkgB	PTHR43827:SF15	2,5-DIKETO-D-GLUCONIC ACID REDUCTASE	METHYLGLYOXAL REDUCTASE DKGB	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616	metabolic process#GO:0008152;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;detoxification#GO:0098754;aldehyde catabolic process#GO:0046185;cellular response to toxic substance#GO:0097237;response to chemical#GO:0042221;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;cellular response to chemical stimulus#GO:0070887;cellular response to stimulus#GO:0051716;cellular detoxification of aldehyde#GO:0110095;ketone metabolic process#GO:0042180;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;response to toxic substance#GO:0009636		reductase#PC00198	
ECOLI|EnsemblGenome=b2512|UniProtKB=P77774	P77774	bamB	PTHR32303:SF26	QUINOPROTEIN ALCOHOL DEHYDROGENASE (CYTOCHROME C)	OUTER MEMBRANE PROTEIN ASSEMBLY FACTOR BAMB		localization within membrane#GO:0051668;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular component organization#GO:0016043;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024	cellular anatomical structure#GO:0110165;membrane#GO:0016020	metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b0132|UniProtKB=P31665	P31665	rpnC	PTHR34611:SF5	INACTIVE RECOMBINATION-PROMOTING NUCLEASE-LIKE PROTEIN RPNE	RECOMBINATION-PROMOTING NUCLEASE RPNA-RELATED	endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520	DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139			
ECOLI|EnsemblGenome=b2463|UniProtKB=P76558	P76558	maeB	PTHR43237:SF4	NADP-DEPENDENT MALIC ENZYME	NADP-DEPENDENT MALIC ENZYME	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3973|UniProtKB=P06709	P06709	birA	PTHR12835:SF5	BIOTIN PROTEIN LIGASE	BIOTIN--PROTEIN LIGASE	ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on a protein#GO:0140096;ligase activity#GO:0016874;catalytic activity#GO:0003824		intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	ligase#PC00142	
ECOLI|EnsemblGenome=b2976|UniProtKB=P37330	P37330	glcB	PTHR42739:SF1	MALATE SYNTHASE G	MALATE SYNTHASE G					
ECOLI|EnsemblGenome=b0407|UniProtKB=P0ADZ7	P0ADZ7	yajC	PTHR33909:SF1	SEC TRANSLOCON ACCESSORY COMPLEX SUBUNIT YAJC	SEC TRANSLOCON ACCESSORY COMPLEX SUBUNIT YAJC			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1697|UniProtKB=P76201	P76201	ydiQ	PTHR21294:SF17	ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT	ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT YDIQ-RELATED				metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2542|UniProtKB=P77650	P77650	hcaD	PTHR43557:SF2	APOPTOSIS-INDUCING FACTOR 1	RIESKE DOMAIN-CONTAINING PROTEIN-RELATED	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1913|UniProtKB=P0A8G0	P0A8G0	uvrC	PTHR30562:SF1	UVRC/OXIDOREDUCTASE	UVRABC SYSTEM PROTEIN C	DNA endonuclease activity#GO:0004520;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;nuclease activity#GO:0004518;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536	DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289	DNA repair complex#GO:1990391;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991	DNA metabolism protein#PC00009;endodeoxyribonuclease#PC00093	
ECOLI|EnsemblGenome=b3028|UniProtKB=P0AEY5	P0AEY5	mdaB	PTHR46305:SF4	FAMILY NOT NAMED	NADPH:QUINONE OXIDOREDUCTASE MDAB	oxidoreductase activity, acting on NAD(P)H#GO:0016651;NAD(P)H dehydrogenase (quinone) activity#GO:0003955;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2872|UniProtKB=P65807	P65807	ygeY	PTHR43808:SF31	ACETYLORNITHINE DEACETYLASE	SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE	hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;catalytic activity#GO:0003824;deacylase activity#GO:0160215;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;L-arginine biosynthetic process#GO:0006526;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525		metabolite interconversion enzyme#PC00262;deacetylase#PC00087	Arginine biosynthesis#P02728>N-actetylornithine deacetylase#P02847
ECOLI|EnsemblGenome=b2890|UniProtKB=P0A8N3	P0A8N3	lysS	PTHR42918:SF17	LYSYL-TRNA SYNTHETASE	LYSINE--TRNA LIGASE-RELATED	binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098	tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047	
ECOLI|EnsemblGenome=b2783|UniProtKB=P0AE72	P0AE72	mazE	PTHR40516:SF1	ANTITOXIN CHPS-RELATED	ANTITOXIN CHPS-RELATED		regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141	protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;transcription repressor complex#GO:0017053		
ECOLI|EnsemblGenome=b3495|UniProtKB=P0AED0	P0AED0	uspA	PTHR46268:SF23	STRESS RESPONSE PROTEIN NHAX	UNIVERSAL STRESS PROTEIN A-RELATED		response to stimulus#GO:0050896;response to stress#GO:0006950			
ECOLI|EnsemblGenome=b2675|UniProtKB=P39452	P39452	nrdE	PTHR11573:SF6	RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN	RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT	nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;catalytic activity#GO:0003824;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ATP binding#GO:0005524;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167	biosynthetic process#GO:0009058;cellular process#GO:0009987;metabolic process#GO:0008152	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;cytosol#GO:0005829;oxidoreductase complex#GO:1990204	oxidoreductase#PC00176;reductase#PC00198	De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo purine biosynthesis#P02738>GDP reductase#P02909;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921
ECOLI|EnsemblGenome=b0463|UniProtKB=P0AE06	P0AE06	acrA	PTHR30158:SF3	ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER	MULTIDRUG EFFLUX PUMP SUBUNIT ACRA-RELATED		response to antibiotic#GO:0046677;xenobiotic transport#GO:0042908;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to toxic substance#GO:0009636;detoxification#GO:0098754	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b0637|UniProtKB=P0AAT6	P0AAT6	rsfS	PTHR21043:SF4	IOJAP SUPERFAMILY ORTHOLOG	RIBOSOMAL SILENCING FACTOR RSFS	ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;ribosomal large subunit binding#GO:0043023;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488	protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;mitochondrial large ribosomal subunit assembly#GO:1902775;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;protein-RNA complex assembly#GO:0022618;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;ribosomal large subunit assembly#GO:0000027;cellular component assembly#GO:0022607;mitochondrial ribosome assembly#GO:0061668;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826			
ECOLI|EnsemblGenome=b0772|UniProtKB=P46130	P46130	ybhC	PTHR31321:SF143	ACYL-COA THIOESTER HYDROLASE YBHC-RELATED	ACYL-COA THIOESTER HYDROLASE YBHC-RELATED	hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689			hydrolase#PC00121	
ECOLI|EnsemblGenome=b2007|UniProtKB=P0A8M6	P0A8M6	tmaR	PTHR39591:SF1	UPF0265 PROTEIN YEEX	POLE-LOCALIZER PROTEIN TMAR			cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b3233|UniProtKB=P0ADW3	P0ADW3	zapG	PTHR39579:SF1	INNER MEMBRANE PROTEIN YHCB	Z-RING ASSOCIATED PROTEIN G			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1822|UniProtKB=P36999	P36999	rlmA	PTHR42912:SF103	METHYLTRANSFERASE	23S RRNA (GUANINE(745)-N(1))-METHYLTRANSFERASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168			methyltransferase#PC00155;transferase#PC00220	
ECOLI|EnsemblGenome=b2843|UniProtKB=Q46938	Q46938	kduI	PTHR38461:SF1	4-DEOXY-L-THREO-5-HEXOSULOSE-URONATE KETOL-ISOMERASE	4-DEOXY-L-THREO-5-HEXOSULOSE-URONATE KETOL-ISOMERASE	metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861	carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;monosaccharide metabolic process#GO:0005996		isomerase#PC00135;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2564|UniProtKB=P0A794	P0A794	pdxJ	PTHR30456:SF0	PYRIDOXINE 5'-PHOSPHATE SYNTHASE	PYRIDOXINE 5'-PHOSPHATE SYNTHASE	catalytic activity#GO:0003824;transferase activity#GO:0016740	metabolic process#GO:0008152;pyridine-containing compound metabolic process#GO:0072524;small molecule biosynthetic process#GO:0044283;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	transferase#PC00220	
ECOLI|EnsemblGenome=b3248|UniProtKB=P25536	P25536	yhdE	PTHR43213:SF5	BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED	BIFUNCTIONAL DTTP_UTP PYROPHOSPHATASE_METHYLTRANSFERASE PROTEIN-RELATED	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;nucleoside triphosphate diphosphatase activity#GO:0047429				
ECOLI|EnsemblGenome=b2780|UniProtKB=P0A7E5	P0A7E5	pyrG	PTHR11550:SF43	CTP SYNTHASE	CTP SYNTHASE	ligase activity, forming carbon-nitrogen bonds#GO:0016879;identical protein binding#GO:0042802;protein binding#GO:0005515;ligase activity#GO:0016874;binding#GO:0005488;catalytic activity#GO:0003824	nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;pyrimidine nucleobase metabolic process#GO:0006206;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	ligase#PC00142;metabolite interconversion enzyme#PC00262	De novo pyrimidine ribonucleotides biosythesis#P02740>CTP synthase#P02931
ECOLI|EnsemblGenome=b3351|UniProtKB=P0A756	P0A756	kefG	PTHR47307:SF1	GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYSTEM ANCILLARY PROTEIN KEFG	GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYSTEM ANCILLARY PROTEIN KEFG	ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;catalytic activity#GO:0003824;NAD(P)H dehydrogenase (quinone) activity#GO:0003955;nucleotide binding#GO:0000166;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;oxidoreductase activity, acting on NAD(P)H#GO:0016651				
ECOLI|EnsemblGenome=b1653|UniProtKB=P30015	P30015	lhr	PTHR47962:SF5	ATP-DEPENDENT HELICASE LHR-RELATED-RELATED	LHR HELICASE_URACIL GLYCOSYLASE	ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;DNA binding#GO:0003677;ATP hydrolysis activity#GO:0016887;nucleic acid binding#GO:0003676;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657				
ECOLI|EnsemblGenome=b0481|UniProtKB=P0AAR3	P0AAR3	ybaK	PTHR30411:SF10	CYTOPLASMIC PROTEIN	CYS-TRNA(PRO)_CYS-TRNA(CYS) DEACYLASE YBAK	catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;deacylase activity#GO:0160215;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101;carboxylic ester hydrolase activity#GO:0052689	tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007			
ECOLI|EnsemblGenome=b3367|UniProtKB=P0AC26	P0AC26	nirC	PTHR30520:SF8	FORMATE TRANSPORTER-RELATED	NITRITE TRANSPORTER NIRC	carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monocarboxylic acid transmembrane transporter activity#GO:0008028;nitrate transmembrane transporter activity#GO:0015112;active transmembrane transporter activity#GO:0022804	carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;inorganic anion transport#GO:0015698;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;establishment of localization#GO:0051234;nitrogen compound transport#GO:0071705	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b1463|UniProtKB=P77567	P77567	nhoA	PTHR11786:SF12	N-HYDROXYARYLAMINE O-ACETYLTRANSFERASE	ARYLAMINE N-ACETYLTRANSFERASE	acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080			acetyltransferase#PC00038	
ECOLI|EnsemblGenome=b0283|UniProtKB=P77183	P77183	paoD	PTHR30388:SF4	ALDEHYDE OXIDOREDUCTASE MOLYBDENUM COFACTOR ASSEMBLY PROTEIN	MOLYBDENUM COFACTOR INSERTION CHAPERONE PAOD	binding#GO:0005488			chaperone#PC00072	
ECOLI|EnsemblGenome=b2317|UniProtKB=P0ABP6	P0ABP6	dedA	PTHR30353:SF0	INNER MEMBRANE PROTEIN DEDA-RELATED	TRANSMEMBRANE PROTEIN					
ECOLI|EnsemblGenome=b2454|UniProtKB=P77277	P77277	eutJ	PTHR32432:SF3	CELL DIVISION PROTEIN FTSA-RELATED	ETHANOLAMINE UTILIZATION PROTEIN EUTJ		cellular process#GO:0009987;type IV pilus-dependent motility#GO:0043107;cell motility#GO:0048870	type IV pilus#GO:0044096;cellular anatomical structure#GO:0110165;cell projection#GO:0042995		
ECOLI|EnsemblGenome=b2480|UniProtKB=P0AE52	P0AE52	bcp	PTHR42801:SF4	THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE	THIOREDOXIN-DEPENDENT PEROXIREDOXIN	peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491	response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;response to stimulus#GO:0050896;homeostatic process#GO:0042592;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	peroxidase#PC00180	
ECOLI|EnsemblGenome=b1870|UniProtKB=P76290	P76290	cmoA	PTHR43861:SF2	TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED	CARBOXY-S-ADENOSYL-L-METHIONINE SYNTHASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168	macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	methyltransferase#PC00155	
ECOLI|EnsemblGenome=b1025|UniProtKB=P75908	P75908	dgcT	PTHR46663:SF4	DIGUANYLATE CYCLASE DGCT-RELATED	DIGUANYLATE CYCLASE DGCT-RELATED	transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779	cell communication#GO:0007154;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular process#GO:0009987		lyase#PC00144;cyclase#PC00079	
ECOLI|EnsemblGenome=b1234|UniProtKB=P0AFR0	P0AFR0	rssA	PTHR14226:SF76	NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER	NTE FAMILY PROTEIN RSSA				hydrolase#PC00121;esterase#PC00097	
ECOLI|EnsemblGenome=b3425|UniProtKB=P0A6V5	P0A6V5	glpE	PTHR43031:SF6	FAD-DEPENDENT OXIDOREDUCTASE	THIOSULFATE SULFURTRANSFERASE GLPE	catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;transferase activity, transferring sulphur-containing groups#GO:0016782	response to stimulus#GO:0050896;response to nutrient levels#GO:0031667		oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b4041|UniProtKB=P0A7A7	P0A7A7	plsB	PTHR12563:SF26	GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE	GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE	acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747	lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;oxoacid metabolic process#GO:0043436;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;small molecule metabolic process#GO:0044281		metabolite interconversion enzyme#PC00262;acyltransferase#PC00042	
ECOLI|EnsemblGenome=b2461|UniProtKB=P76556	P76556	eutP	PTHR40453:SF2	PROTEIN YOEF	ACETATE KINASE EUTP-RELATED					
ECOLI|EnsemblGenome=b1732|UniProtKB=P21179	P21179	katE	PTHR42821:SF1	CATALASE	CATALASE-B	oxidoreductase activity#GO:0016491;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;heme binding#GO:0020037;tetrapyrrole binding#GO:0046906;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;binding#GO:0005488	response to stress#GO:0006950;cellular process#GO:0009987;response to stimulus#GO:0050896;catabolic process#GO:0009056;hydrogen peroxide metabolic process#GO:0042743;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;response to oxidative stress#GO:0006979	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	peroxidase#PC00180	
ECOLI|EnsemblGenome=b2028|UniProtKB=P76373	P76373	ugd	PTHR43750:SF2	UDP-GLUCOSE 6-DEHYDROGENASE TUAD	UDP-GLUCOSE 6-DEHYDROGENASE	catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614			dehydrogenase#PC00092;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0933|UniProtKB=P0AAI1	P0AAI1	ssuB	PTHR42788:SF17	TAURINE IMPORT ATP-BINDING PROTEIN-RELATED	ALIPHATIC SULFONATES IMPORT ATP-BINDING PROTEIN SSUB				ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b0540|UniProtKB=P0CF68	P0CF68	insE3	PTHR33215:SF6	PROTEIN DISTAL ANTENNA	TRANSPOSASE INSE FOR INSERTION SEQUENCE IS3A-RELATED					
ECOLI|EnsemblGenome=b2311|UniProtKB=P0AG03	P0AG03	ubiX	PTHR43374:SF1	FLAVIN PRENYLTRANSFERASE	FLAVIN PRENYLTRANSFERASE UBIX	prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740	metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ubiquinone biosynthetic process#GO:0006744		transferase#PC00220	
ECOLI|EnsemblGenome=b3991|UniProtKB=P30139	P30139	thiG	PTHR34266:SF2	THIAZOLE SYNTHASE	THIAZOLE SYNTHASE		organophosphate biosynthetic process#GO:0090407;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793;alcohol biosynthetic process#GO:0046165;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987	catalytic complex#GO:1902494;protein-containing complex#GO:0032991		
ECOLI|EnsemblGenome=b0936|UniProtKB=P75853	P75853	ssuA	PTHR30024:SF42	ALIPHATIC SULFONATES-BINDING PROTEIN-RELATED	ALIPHATIC SULFONATES-BINDING PROTEIN-RELATED					
ECOLI|EnsemblGenome=b2987|UniProtKB=P43676	P43676	pitB	PTHR11101:SF65	PHOSPHATE TRANSPORTER	LOW-AFFINITY INORGANIC PHOSPHATE TRANSPORTER PITA-RELATED	active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;phosphate transmembrane transporter activity#GO:0005315;secondary active transmembrane transporter activity#GO:0015291	phosphate ion transport#GO:0006817;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b2441|UniProtKB=P0AEJ6	P0AEJ6	eutB	PTHR39329:SF1	ETHANOLAMINE AMMONIA-LYASE HEAVY CHAIN	ETHANOLAMINE AMMONIA-LYASE LARGE SUBUNIT	lyase activity#GO:0016829;catalytic activity#GO:0003824	amine catabolic process#GO:0009310;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;amine metabolic process#GO:0009308;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;catalytic complex#GO:1902494	metabolite interconversion enzyme#PC00262;lyase#PC00144	
ECOLI|EnsemblGenome=b3842|UniProtKB=P0AFW0	P0AFW0	rfaH	PTHR30265:SF7	RHO-INTERACTING TRANSCRIPTION TERMINATION FACTOR NUSG	TRANSCRIPTION ANTITERMINATION PROTEIN RFAH	transcription regulator activity#GO:0140110	negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;negative regulation of metabolic process#GO:0009892;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of DNA-templated transcription#GO:0006355;negative regulation of protein-containing complex disassembly#GO:0043242;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of cellular component organization#GO:0051129;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b1340|UniProtKB=P76053	P76053	smrA	PTHR35562:SF2	DNA ENDONUCLEASE SMRA-RELATED	DNA ENDONUCLEASE SMRA-RELATED	endonuclease activity#GO:0004519;nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640			DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b0112|UniProtKB=P15993	P15993	aroP	PTHR43495:SF4	GABA PERMEASE	AROMATIC AMINO ACID TRANSPORT PROTEIN AROP	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	secondary carrier transporter#PC00258;amino acid transporter#PC00046;transporter#PC00227	
ECOLI|EnsemblGenome=b0062|UniProtKB=P08202	P08202	araA	PTHR38464:SF1	L-ARABINOSE ISOMERASE	L-ARABINOSE ISOMERASE	catalytic activity#GO:0003824;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853		cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	isomerase#PC00135	
ECOLI|EnsemblGenome=b2076|UniProtKB=P76399	P76399	mdtC	PTHR32063:SF34	SWARMING MOTILITY PROTEIN SWRC-RELATED	MULTIDRUG RESISTANCE PROTEIN MDTC					
ECOLI|EnsemblGenome=b1630|UniProtKB=P76182	P76182	rsxD	PTHR30578:SF0	ELECTRON TRANSPORT COMPLEX PROTEIN RNFD	ION-TRANSLOCATING OXIDOREDUCTASE COMPLEX SUBUNIT D			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b2604|UniProtKB=P46139	P46139	dgcN	PTHR45138:SF28	REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM	DIGUANYLATE CYCLASE DGCN	catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772	cell adhesion#GO:0007155;single-species biofilm formation#GO:0044010;negative regulation of cellular process#GO:0048523;cell-substrate adhesion#GO:0031589;regulation of cell motility#GO:2000145;cellular process#GO:0009987;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;regulation of cellular process#GO:0050794	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b1328|UniProtKB=P77333	P77333	pgrR	PTHR30537:SF1	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR PGRR	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789		helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b2870|UniProtKB=Q46803	Q46803	ygeW	PTHR45753:SF3	ORNITHINE CARBAMOYLTRANSFERASE, MITOCHONDRIAL	CARBAMOYLTRANSFERASE YGEW-RELATED	transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;L-arginine biosynthetic process#GO:0006526;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525		transferase#PC00220	Arginine biosynthesis#P02728>Ornithine carbamoyl transferase#P02846
ECOLI|EnsemblGenome=b3996|UniProtKB=P32664	P32664	nudC	PTHR42904:SF6	NUDIX HYDROLASE, NUDC SUBFAMILY	NAD-CAPPED RNA HYDROLASE NUDT12	hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818	organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;pyridine nucleotide catabolic process#GO:0019364;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;NADP+ metabolic process#GO:0006739;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496		hydrolase#PC00121	
ECOLI|EnsemblGenome=b0419|UniProtKB=P77735	P77735	yajO	PTHR43364:SF4	NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED	NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN				oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1233|UniProtKB=P37052	P37052	ychJ	PTHR33747:SF1	UPF0225 PROTEIN SCO1677	ADENYLATE CYCLASE-ASSOCIATED CAP C-TERMINAL DOMAIN-CONTAINING PROTEIN					
ECOLI|EnsemblGenome=b0683|UniProtKB=P0A9A9	P0A9A9	fur	PTHR33202:SF2	ZINC UPTAKE REGULATION PROTEIN	FERRIC UPTAKE REGULATION PROTEIN	sequence-specific DNA binding#GO:0043565;metal ion binding#GO:0046872;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific double-stranded DNA binding#GO:1990837;zinc ion binding#GO:0008270;double-stranded DNA binding#GO:0003690;cation binding#GO:0043169;DNA binding#GO:0003677;transition metal ion binding#GO:0046914;transcription cis-regulatory region binding#GO:0000976;ion binding#GO:0043167;small molecule binding#GO:0036094;nucleic acid binding#GO:0003676	negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b1331|UniProtKB=P0CE52	P0CE52	insH4	PTHR35604:SF2	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097	cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b4022|UniProtKB=P32684	P32684	rluF	PTHR21600:SF75	MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE	DUAL-SPECIFICITY RNA PSEUDOURIDINE SYNTHASE RLUF	intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;isomerase activity#GO:0016853	metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA modification#GO:0000154;pseudouridine synthesis#GO:0001522;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613		RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b3300|UniProtKB=P0AGA2	P0AGA2	secY	PTHR10906:SF2	SECY/SEC61-ALPHA FAMILY MEMBER	PROTEIN TRANSLOCASE SUBUNIT SECY	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transmembrane protein transporter activity#GO:0008320	protein targeting#GO:0006605;localization within membrane#GO:0051668;protein transport#GO:0015031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of protein localization to endoplasmic reticulum#GO:0072599;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;transport#GO:0006810;intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612;protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594		transporter#PC00227	
ECOLI|EnsemblGenome=b0469|UniProtKB=P69503	P69503	apt	PTHR11776:SF38	ADENINE PHOSPHORIBOSYLTRANSFERASE	ADENINE PHOSPHORIBOSYLTRANSFERASE	glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740	nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	transferase#PC00220	Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphoribosyl transferase#P02810
ECOLI|EnsemblGenome=b3374|UniProtKB=P45543	P45543	frlD	PTHR43085:SF41	HEXOKINASE FAMILY MEMBER	FRUCTOSELYSINE 6-KINASE	transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824			carbohydrate kinase#PC00065;metabolite interconversion enzyme#PC00262;transferase#PC00220	
ECOLI|EnsemblGenome=b1798|UniProtKB=P76249	P76249	leuE	PTHR30086:SF15	ARGININE EXPORTER PROTEIN ARGO	LEUCINE EFFLUX PROTEIN	amino acid transmembrane transporter activity#GO:0015171;branched-chain amino acid transmembrane transporter activity#GO:0015658;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;neutral L-amino acid transmembrane transporter activity#GO:0015175;L-amino acid transmembrane transporter activity#GO:0015179	branched-chain amino acid transport#GO:0015803;localization#GO:0051179;neutral amino acid transport#GO:0015804;establishment of localization#GO:0051234;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;amino acid transport#GO:0006865;L-leucine transport#GO:0015820;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b4245|UniProtKB=P0A786	P0A786	pyrB	PTHR11405:SF16	CARBAMOYLTRANSFERASE FAMILY MEMBER	ASPARTATE CARBAMOYLTRANSFERASE, CHLOROPLASTIC	ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	metabolite interconversion enzyme#PC00262;ligase#PC00142	De novo pyrimidine ribonucleotides biosythesis#P02740>Aspartate carbamoyltransferase#P02926
ECOLI|EnsemblGenome=b2809|UniProtKB=P65292	P65292	ygdI	PTHR37011:SF2	POT FAMILY PEPTIDE TRANSPORT PROTEIN-RELATED	OUTER MEMBRANE LIPOPROTEIN					
ECOLI|EnsemblGenome=b0453|UniProtKB=P77717	P77717	ybaY	PTHR38013:SF1	GLYCOPROTEIN/POLYSACCHARIDE METABOLISM	LIPOPROTEIN					
ECOLI|EnsemblGenome=b4375|UniProtKB=P0A7I4	P0A7I4	prfC	PTHR43556:SF2	PEPTIDE CHAIN RELEASE FACTOR RF3	PEPTIDE CHAIN RELEASE FACTOR RF3	translation factor activity#GO:0180051	protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;translation#GO:0006412;translational termination#GO:0006415;protein-containing complex disassembly#GO:0032984;protein biosynthetic process#GO:0160307;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	translational protein#PC00263;translation factor#PC00223;translation release factor#PC00225	
ECOLI|EnsemblGenome=b2514|UniProtKB=P60906	P60906	hisS	PTHR43707:SF7	HISTIDYL-TRNA SYNTHETASE	HISTIDINE--TRNA LIGASE	ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098	translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	aminoacyl-tRNA synthetase#PC00047	
ECOLI|EnsemblGenome=b0490|UniProtKB=P77279	P77279	fetA	PTHR43423:SF12	ABC TRANSPORTER I FAMILY MEMBER 17	IRON EXPORT ATP-BINDING PROTEIN FETA-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b3438|UniProtKB=P0ACP5	P0ACP5	gntR	PTHR30146:SF2	LACI-RELATED TRANSCRIPTIONAL REPRESSOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR GNTR	double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468		Lambda repressor-like transcription factor#PC00245;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b4315|UniProtKB=P39264	P39264	fimI	PTHR33420:SF12	FIMBRIAL SUBUNIT ELFA-RELATED	FIMBRIN-LIKE PROTEIN FIMI-RELATED		cell-substrate adhesion#GO:0031589;cell adhesion#GO:0007155;cellular process#GO:0009987;single-species biofilm formation#GO:0044010	cell projection#GO:0042995;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1902|UniProtKB=P0A9A2	P0A9A2	ftnB	PTHR11431:SF40	FERRITIN	BACTERIAL NON-HEME FERRITIN-LIKE PROTEIN	ferrous iron binding#GO:0008198;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;iron ion binding#GO:0005506;oxidoreductase activity, acting on metal ions#GO:0016722;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169		cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	storage protein#PC00210	
ECOLI|EnsemblGenome=b2805|UniProtKB=P0ACK8	P0ACK8	fucR	PTHR30363:SF49	HTH-TYPE TRANSCRIPTIONAL REGULATOR SRLR-RELATED	L-FUCOSE OPERON ACTIVATOR	double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789		DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b3264|UniProtKB=P0ACT2	P0ACT2	envR	PTHR43479:SF11	ACREF/ENVCD OPERON REPRESSOR-RELATED	ACREF_ENVCD OPERON REPRESSOR-RELATED	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110				
ECOLI|EnsemblGenome=b0989|UniProtKB=P0A982	P0A982	cspH	PTHR11544:SF138	COLD SHOCK DOMAIN CONTAINING PROTEINS	COLD SHOCK PROTEIN CSPA-RELATED					
ECOLI|EnsemblGenome=b0815|UniProtKB=P75785	P75785	opgE	PTHR30443:SF4	INNER MEMBRANE PROTEIN	PHOSPHOETHANOLAMINE TRANSFERASE OPGE-RELATED	phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772	carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;oligosaccharide metabolic process#GO:0009311;primary metabolic process#GO:0044238;liposaccharide metabolic process#GO:1903509;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;lipopolysaccharide biosynthetic process#GO:0009103;lipopolysaccharide core region biosynthetic process#GO:0009244;polysaccharide biosynthetic process#GO:0000271;lipopolysaccharide metabolic process#GO:0008653;oligosaccharide biosynthetic process#GO:0009312	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b0016|UniProtKB=P0CF91	P0CF91	insL1	PTHR33258:SF1	TRANSPOSASE INSL FOR INSERTION SEQUENCE ELEMENT IS186A-RELATED	TRANSPOSASE INSL FOR INSERTION SEQUENCE ELEMENT IS186A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b3639|UniProtKB=P0ABQ0	P0ABQ0	coaBC	PTHR14359:SF6	HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY	PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE	nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;carbon-carbon lyase activity#GO:0016830;ribonucleotide binding#GO:0032553;carboxy-lyase activity#GO:0016831;carbohydrate derivative binding#GO:0097367;catalytic activity#GO:0003824;lyase activity#GO:0016829;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094	nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152	catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991	metabolite interconversion enzyme#PC00262;decarboxylase#PC00089	Coenzyme A biosynthesis#P02736>Pantothenoylcysteine decarboxylase#P02883;Coenzyme A biosynthesis#P02736>Pantothenate cysteine ligase#P02882
ECOLI|EnsemblGenome=b3820|UniProtKB=P0ADP2	P0ADP2	yigI	PTHR43240:SF20	1,4-DIHYDROXY-2-NAPHTHOYL-COA THIOESTERASE 1	MEDIUM_LONG-CHAIN ACYL-COA THIOESTERASE YIGI				metabolite interconversion enzyme#PC00262;esterase#PC00097	
ECOLI|EnsemblGenome=b1996|UniProtKB=P0CF55	P0CF55	insD3	PTHR37936:SF3	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b0575|UniProtKB=P38054	P38054	cusA	PTHR32063:SF19	SWARMING MOTILITY PROTEIN SWRC-RELATED	CATION EFFLUX SYSTEM PROTEIN CUSA					
ECOLI|EnsemblGenome=b2134|UniProtKB=P0AFI5	P0AFI5	pbpG	PTHR21581:SF26	D-ALANYL-D-ALANINE CARBOXYPEPTIDASE	D-ALANYL-D-ALANINE ENDOPEPTIDASE				protease#PC00190;serine protease#PC00203	
ECOLI|EnsemblGenome=b3980|UniProtKB=P0CE48	P0CE48	tufB	PTHR43721:SF22	ELONGATION FACTOR TU-RELATED	ELONGATION FACTOR TU 1-RELATED	translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051	protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987		translation elongation factor#PC00222	
ECOLI|EnsemblGenome=b1105|UniProtKB=P0AB38	P0AB38	lpoB	PTHR40593:SF1	PENICILLIN-BINDING PROTEIN ACTIVATOR LPOB	PENICILLIN-BINDING PROTEIN ACTIVATOR LPOB	enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234	cell wall organization or biogenesis#GO:0071554;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cell wall macromolecule biosynthetic process#GO:0044038;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycosaminoglycan biosynthetic process#GO:0006024;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;peptidoglycan metabolic process#GO:0000270;peptidoglycan-based cell wall biogenesis#GO:0009273;peptidoglycan biosynthetic process#GO:0009252;glycosaminoglycan metabolic process#GO:0030203;aminoglycan biosynthetic process#GO:0006023;cell wall biogenesis#GO:0042546;cell wall macromolecule metabolic process#GO:0044036;aminoglycan metabolic process#GO:0006022	outer membrane#GO:0019867;extracellular region#GO:0005576;side of membrane#GO:0098552;external encapsulating structure#GO:0030312;cell outer membrane#GO:0009279;membrane#GO:0016020;cell envelope#GO:0030313;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1890|UniProtKB=P09348	P09348	motA	PTHR30433:SF4	CHEMOTAXIS PROTEIN MOTA	MOTILITY PROTEIN A		cilium or flagellum-dependent cell motility#GO:0001539;cellular process#GO:0009987;archaeal or bacterial-type flagellum-dependent cell motility#GO:0097588;bacterial-type flagellum-dependent swarming motility#GO:0071978;bacterial-type flagellum-dependent cell motility#GO:0071973;cell motility#GO:0048870	cell projection#GO:0042995;plasma membrane#GO:0005886;bacterial-type flagellum#GO:0009288;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;membraneless organelle#GO:0043228		
ECOLI|EnsemblGenome=b2212|UniProtKB=P05050	P05050	alkB	PTHR16557:SF2	ALKYLATED DNA REPAIR PROTEIN ALKB-RELATED	DNA N(6)-METHYLADENINE DEMETHYLASE ALKBH1B-RELATED	2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;cation binding#GO:0043169;dioxygenase activity#GO:0051213;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;ion binding#GO:0043167;catalytic activity, acting on RNA#GO:0140098;demethylase activity#GO:0032451;iron ion binding#GO:0005506;catalytic activity, acting on DNA#GO:0140097;ferrous iron binding#GO:0008198;metal ion binding#GO:0046872;binding#GO:0005488	cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;RNA modification#GO:0009451;metabolic process#GO:0008152;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b3440|UniProtKB=P46853	P46853	yhhX	PTHR43708:SF7	CONSERVED EXPRESSED OXIDOREDUCTASE (EUROFUNG)	OXIDOREDUCTASE	oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824	biosynthetic process#GO:0009058;metabolic process#GO:0008152;antibiotic biosynthetic process#GO:0017000;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3706|UniProtKB=P25522	P25522	mnmE	PTHR42714:SF2	TRNA MODIFICATION GTPASE GTPBP3	TRNA MODIFICATION GTPASE MNME		tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	RNA metabolism protein#PC00031;RNA methyltransferase#PC00033	
ECOLI|EnsemblGenome=b4320|UniProtKB=P08191	P08191	fimH	PTHR33420:SF14	FIMBRIAL SUBUNIT ELFA-RELATED	TYPE 1 FIMBRIN D-MANNOSE SPECIFIC ADHESIN		cell adhesion#GO:0007155;cellular process#GO:0009987;single-species biofilm formation#GO:0044010;cell-substrate adhesion#GO:0031589	cellular anatomical structure#GO:0110165;cell projection#GO:0042995		
ECOLI|EnsemblGenome=b4077|UniProtKB=P21345	P21345	gltP	PTHR42865:SF7	PROTON/GLUTAMATE-ASPARTATE SYMPORTER	GLUTAMATE_ASPARTATE-PROTON SYMPORTER GLTP	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	dicarboxylic acid transport#GO:0006835;establishment of localization#GO:0051234;localization#GO:0051179;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	primary active transporter#PC00068	Ionotropic glutamate receptor pathway#P00037>EAAT#P01011
ECOLI|EnsemblGenome=b1742|UniProtKB=P76214	P76214	ves	PTHR37943:SF1	PROTEIN VES	PROTEIN VES					
ECOLI|EnsemblGenome=b1215|UniProtKB=P0A715	P0A715	kdsA	PTHR21057:SF3	PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE	2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765	carbohydrate biosynthetic process#GO:0016051;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;lipopolysaccharide biosynthetic process#GO:0009103;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;small molecule metabolic process#GO:0044281;liposaccharide metabolic process#GO:1903509;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;lipopolysaccharide metabolic process#GO:0008653;polysaccharide biosynthetic process#GO:0000271;oxoacid metabolic process#GO:0043436	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	lyase#PC00144;aldolase#PC00044;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b4292|UniProtKB=P23485	P23485	fecR	PTHR30273:SF3	PERIPLASMIC SIGNAL SENSOR AND SIGMA FACTOR ACTIVATOR FECR-RELATED	FERRIC CITRATE UPTAKE SIGMA FACTOR REGULATOR FECR					
ECOLI|EnsemblGenome=b4502|UniProtKB=P0AFT8	P0AFT8	yeiW	PTHR36931:SF1	UPF0153 PROTEIN YEIW	UPF0153 PROTEIN YEIW					
ECOLI|EnsemblGenome=b1536|UniProtKB=P31130	P31130	ydeI	PTHR36571:SF2	PROTEIN YGIW	PERIPLASMIC PROTEIN		response to metal ion#GO:0010038;response to cadmium ion#GO:0046686;detoxification of inorganic compound#GO:0061687;response to stress#GO:0006950;detoxification#GO:0098754;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;response to chemical#GO:0042221			
ECOLI|EnsemblGenome=b3092|UniProtKB=P0A8G3	P0A8G3	uxaC	PTHR30068:SF4	URONATE ISOMERASE	URONATE ISOMERASE				isomerase#PC00135;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1292|UniProtKB=P0AGH5	P0AGH5	sapC	PTHR43386:SF5	OLIGOPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN APPC	PUTRESCINE EXPORT SYSTEM PERMEASE PROTEIN SAPC	polyamine transmembrane transporter activity#GO:0015203;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b0881|UniProtKB=P0A8Q6	P0A8Q6	clpS	PTHR33473:SF19	ATP-DEPENDENT CLP PROTEASE ADAPTER PROTEIN CLPS1, CHLOROPLASTIC	ATP-DEPENDENT CLP PROTEASE ADAPTER PROTEIN CLPS				scaffold/adaptor protein#PC00226	
ECOLI|EnsemblGenome=b2726|UniProtKB=P0A700	P0A700	hypA	PTHR34535:SF3	HYDROGENASE MATURATION FACTOR HYPA	HYDROGENASE MATURATION FACTOR HYPA	metal ion binding#GO:0046872;cation binding#GO:0043169;zinc ion binding#GO:0008270;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914	primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170			
ECOLI|EnsemblGenome=b1435|UniProtKB=P76104	P76104	rlhA	PTHR30217:SF14	PEPTIDASE U32 FAMILY	23S RRNA 5-HYDROXYCYTIDINE C2501 SYNTHASE		macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238		protease#PC00190	
ECOLI|EnsemblGenome=b4106|UniProtKB=P16677	P16677	phnC	PTHR43166:SF6	AMINO ACID IMPORT ATP-BINDING PROTEIN	PHOSPHONATES IMPORT ATP-BINDING PROTEIN PHNC	active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857			primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b3195|UniProtKB=P63386	P63386	mlaF	PTHR43023:SF6	PROTEIN TRIGALACTOSYLDIACYLGLYCEROL 3, CHLOROPLASTIC	INTERMEMBRANE PHOSPHOLIPID TRANSPORT SYSTEM ATP-BINDING PROTEIN MLAF	ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;lipid transfer activity#GO:0120013;ATP hydrolysis activity#GO:0016887;phospholipid transfer activity#GO:0120014;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;transporter activity#GO:0005215;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111	membrane organization#GO:0061024;phospholipid transport#GO:0015914;intermembrane phospholipid transfer#GO:0120010;lipid transport#GO:0006869;organophosphate ester transport#GO:0015748;cellular process#GO:0009987;cellular component organization#GO:0016043;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;intermembrane lipid transfer#GO:0120009;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;lipid localization#GO:0010876	transporter complex#GO:1990351;protein-containing complex#GO:0032991	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b0898|UniProtKB=P21503	P21503	ycaD	PTHR23521:SF2	TRANSPORTER MFS SUPERFAMILY	MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b0587|UniProtKB=P26266	P26266	fepE	PTHR32309:SF13	TYROSINE-PROTEIN KINASE	FERRIC ENTEROBACTIN TRANSPORT PROTEIN FEPE	protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;catalytic activity, acting on a protein#GO:0140096		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	non-receptor tyrosine protein kinase#PC00168	
ECOLI|EnsemblGenome=b4179|UniProtKB=P21499	P21499	rnr	PTHR23355:SF9	RIBONUCLEASE	RIBONUCLEASE R		RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007		exoribonuclease#PC00099	
ECOLI|EnsemblGenome=b0197|UniProtKB=P28635	P28635	metQ	PTHR30429:SF1	D-METHIONINE-BINDING LIPOPROTEIN METQ	D-METHIONINE-BINDING LIPOPROTEIN METQ-RELATED		import across plasma membrane#GO:0098739;carboxylic acid transmembrane transport#GO:1905039;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;import into cell#GO:0098657;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;amino acid transport#GO:0006865	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0968|UniProtKB=P0AB65	P0AB65	yccX	PTHR10029:SF3	ACYLPHOSPHATASE	ACYLPHOSPHATASE-1	hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817			metabolite interconversion enzyme#PC00262;phosphatase#PC00181	
ECOLI|EnsemblGenome=b3988|UniProtKB=P0A8T7	P0A8T7	rpoC	PTHR19376:SF54	DNA-DIRECTED RNA POLYMERASE	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'				DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b0758|UniProtKB=P09148	P09148	galT	PTHR11943:SF1	GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE	GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772	primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	nucleotidyltransferase#PC00174	Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992;Fructose galactose metabolism#P02744>Hexose 1-P uridyltransferase#P02964
ECOLI|EnsemblGenome=b1179|UniProtKB=P0AB43	P0AB43	ycgL	PTHR38109:SF1	PROTEIN YCGL	PROTEIN YCGL					
ECOLI|EnsemblGenome=b1181|UniProtKB=P0A8L5	P0A8L5	ycgN	PTHR37421:SF1	UPF0260 PROTEIN YCGN	UPF0260 PROTEIN YCGN					
ECOLI|EnsemblGenome=b2383|UniProtKB=P77439	P77439	fryA	PTHR46244:SF4	PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE	MULTIPHOSPHORYL TRANSFER PROTEIN 1-RELATED	transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;transferase activity, transferring phosphorus-containing groups#GO:0016772	transport#GO:0006810;carbohydrate derivative transport#GO:1901264;localization#GO:0051179;establishment of localization#GO:0051234		protein modifying enzyme#PC00260	
ECOLI|EnsemblGenome=b0630|UniProtKB=P60720	P60720	lipB	PTHR10993:SF20	OCTANOYLTRANSFERASE	OCTANOYLTRANSFERASE				transferase#PC00220	Lipoate_biosynthesis#P02750>Lipoyl-protein ligase#P03003
ECOLI|EnsemblGenome=b1529|UniProtKB=P0AEY1	P0AEY1	marC	PTHR33508:SF2	UPF0056 MEMBRANE PROTEIN YHCE	UPF0056 INNER MEMBRANE PROTEIN MARC			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b2583|UniProtKB=Q47319	Q47319	tapT	PTHR21392:SF1	TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2	TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE					
ECOLI|EnsemblGenome=b4546|UniProtKB=P0AD40	P0AD40	ypeB	PTHR40613:SF1	FAMILY NOT NAMED	DUF3820 FAMILY PROTEIN					
ECOLI|EnsemblGenome=b1729|UniProtKB=P77529	P77529	tcyP	PTHR42865:SF5	PROTON/GLUTAMATE-ASPARTATE SYMPORTER	L-CYSTINE TRANSPORTER TCYP	L-amino acid transmembrane transporter activity#GO:0015179;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	primary active transporter#PC00068	
ECOLI|EnsemblGenome=b3006|UniProtKB=P0ABU7	P0ABU7	exbB	PTHR30625:SF16	PROTEIN TOLQ	BIOPOLYMER TRANSPORT PROTEIN EXBB		siderophore-iron import into cell#GO:0033214;monoatomic ion homeostasis#GO:0050801;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;iron coordination entity transport#GO:1901678;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;intracellular iron ion homeostasis#GO:0006879;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;iron import into cell#GO:0033212;cellular localization#GO:0051641;siderophore-dependent iron import pathway#GO:0180060;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;iron ion transport#GO:0006826	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1296|UniProtKB=P76037	P76037	puuP	PTHR42770:SF8	AMINO ACID TRANSPORTER-RELATED	PUTRESCINE IMPORTER PUUP	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227;secondary carrier transporter#PC00258;amino acid transporter#PC00046	
ECOLI|EnsemblGenome=b2723|UniProtKB=P16429	P16429	hycC	PTHR42682:SF3	HYDROGENASE-4 COMPONENT F	FORMATE HYDROGENLYASE SUBUNIT 3-RELATED		generation of precursor metabolites and energy#GO:0006091;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;electron transport chain#GO:0022900;anaerobic electron transport chain#GO:0019645;anaerobic respiration#GO:0009061;small molecule metabolic process#GO:0044281	protein-containing complex#GO:0032991;oxidoreductase complex#GO:1990204;catalytic complex#GO:1902494	oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0896|UniProtKB=P18777	P18777	dmsC	PTHR38095:SF2	ANAEROBIC DIMETHYL SULFOXIDE REDUCTASE CHAIN YNFH	ANAEROBIC DIMETHYL SULFOXIDE REDUCTASE CHAIN C	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824	metabolic process#GO:0008152;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;anaerobic respiration#GO:0009061	cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	reductase#PC00198	
ECOLI|EnsemblGenome=b3614|UniProtKB=P37691	P37691	yibQ	PTHR30105:SF2	UNCHARACTERIZED YIBQ-RELATED	HYPOTHETICAL EXPORTED PROTEIN					
ECOLI|Gene_OrderedLocusName=JW4040|UniProtKB=P07658	P07658	fdhF	PTHR43105:SF13	RESPIRATORY NITRATE REDUCTASE	NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL			cellular anatomical structure#GO:0110165;membrane#GO:0016020	reductase#PC00198;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0837|UniProtKB=P75804	P75804	yliI	PTHR19328:SF13	HEDGEHOG-INTERACTING PROTEIN	HIPL1 PROTEIN				protein-binding activity modulator#PC00095	
ECOLI|EnsemblGenome=b2153|UniProtKB=P0A6T5	P0A6T5	folE	PTHR11109:SF7	GTP CYCLOHYDROLASE I	GTP CYCLOHYDROLASE 1	catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787	small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;biosynthetic process#GO:0009058;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	hydrolase#PC00121;metabolite interconversion enzyme#PC00262	Tetrahydrofolate biosynthesis#P02742>GTP cyclohydrolase#P02951
ECOLI|EnsemblGenome=b2302|UniProtKB=P77526	P77526	yfcG	PTHR44051:SF25	GLUTATHIONE S-TRANSFERASE-RELATED	DISULFIDE-BOND OXIDOREDUCTASE YFCG	disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;transferase activity#GO:0016740;glutathione transferase activity#GO:0004364		cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	transferase#PC00220;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0525|UniProtKB=P23869	P23869	ppiB	PTHR43246:SF11	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE CYP38, CHLOROPLASTIC	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE B	catalytic activity#GO:0003824;cis-trans isomerase activity#GO:0016859;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096			chaperone#PC00072	
ECOLI|EnsemblGenome=b0959|UniProtKB=P75869	P75869	sxy	PTHR36121:SF1	PROTEIN SXY	PROTEIN SXY		regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789			
ECOLI|EnsemblGenome=b3992|UniProtKB=P30138	P30138	thiF	PTHR10953:SF240	UBIQUITIN-ACTIVATING ENZYME E1	SULFUR CARRIER PROTEIN THIS ADENYLYLTRANSFERASE	sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234	
ECOLI|EnsemblGenome=b3056|UniProtKB=P06961	P06961	cca	PTHR47545:SF1	MULTIFUNCTIONAL CCA PROTEIN	MULTIFUNCTIONAL CCA PROTEIN	transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101	primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;catabolic process#GO:0009056;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;tRNA 3'-end processing#GO:0042780;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170			
ECOLI|EnsemblGenome=b3557|UniProtKB=P19768	P19768	insJ	PTHR33795:SF1	INSERTION ELEMENT IS150 PROTEIN INSJ	INSERTION ELEMENT IS150 PROTEIN INSJ					
ECOLI|EnsemblGenome=b2066|UniProtKB=P0A8F4	P0A8F4	udk	PTHR10285:SF235	URIDINE KINASE	URIDINE KINASE	nucleoside kinase activity#GO:0019206;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205		intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	kinase#PC00137;nucleotide kinase#PC00172	Salvage pyrimidine ribonucleotides#P02775>Uridine kinase#P03150;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;Salvage pyrimidine ribonucleotides#P02775>Cytidine kinase#P03149
ECOLI|EnsemblGenome=b2689|UniProtKB=P0ADR0	P0ADR0	yqaA	PTHR42709:SF4	ALKALINE PHOSPHATASE LIKE PROTEIN	INNER MEMBRANE PROTEIN YQAA		bacterial-type flagellum-dependent cell motility#GO:0071973;cell motility#GO:0048870;archaeal or bacterial-type flagellum-dependent cell motility#GO:0097588;bacterial-type flagellum-dependent swarming motility#GO:0071978;cilium or flagellum-dependent cell motility#GO:0001539;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	phosphatase#PC00181	
ECOLI|EnsemblGenome=b0270|UniProtKB=P75683	P75683	yagG	PTHR11328:SF52	MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN	INNER MEMBRANE SYMPORTER YICJ-RELATED		localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	primary active transporter#PC00068	
ECOLI|EnsemblGenome=b0859|UniProtKB=P75817	P75817	rlmC	PTHR11061:SF50	RNA M5U METHYLTRANSFERASE	23S RRNA (URACIL(747)-C(5))-METHYLTRANSFERASE RLMC	catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640	macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;rRNA base methylation#GO:0070475;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;methylation#GO:0032259;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA modification#GO:0000154		RNA methyltransferase#PC00033	
ECOLI|EnsemblGenome=b1269|UniProtKB=P37765	P37765	rluB	PTHR47683:SF3	PSEUDOURIDINE SYNTHASE FAMILY PROTEIN-RELATED	RIBOSOMAL LARGE SUBUNIT PSEUDOURIDINE SYNTHASE B					
ECOLI|EnsemblGenome=b0338|UniProtKB=P27111	P27111	cynR	PTHR30346:SF28	TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED	HTH-TYPE TRANSCRIPTIONAL REGULATOR CYNR	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141	protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991	winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b0049|UniProtKB=P05637	P05637	apaH	PTHR42850:SF11	METALLOPHOSPHOESTERASE	BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE [SYMMETRICAL]	phosphatase activity#GO:0016791;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on ester bonds#GO:0016788;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787	metabolic process#GO:0008152;RNA decapping#GO:0110154;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	phosphatase#PC00181;hydrolase#PC00121	
ECOLI|EnsemblGenome=b1241|UniProtKB=P0A9Q7	P0A9Q7	adhE	PTHR11496:SF112	ALCOHOL DEHYDROGENASE	BIFUNCTIONAL ALDEHYDE-ALCOHOL DEHYDROGENASE ADHE	alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455			dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b2271|UniProtKB=P76482	P76482	yfbL	PTHR12147:SF59	METALLOPEPTIDASE M28 FAMILY MEMBER	ALKALINE PHOSPHATASE ISOZYME CONVERSION PROTEIN		protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152		protease#PC00190;metalloprotease#PC00153	
ECOLI|EnsemblGenome=b0340|UniProtKB=P00816	P00816	cynS	PTHR34186:SF2	CYANATE HYDRATASE	CYANATE HYDRATASE	hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824	catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152		lyase#PC00144;hydratase#PC00120	
ECOLI|EnsemblGenome=b1970|UniProtKB=P76341	P76341	hiuH	PTHR10395:SF7	URICASE AND TRANSTHYRETIN-RELATED	5-HYDROXYISOURATE HYDROLASE		primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086		hydrolase#PC00121	
ECOLI|EnsemblGenome=b3752|UniProtKB=P0A9J6	P0A9J6	rbsK	PTHR10584:SF166	SUGAR KINASE	RIBOKINASE	phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200		cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	kinase#PC00137;carbohydrate kinase#PC00065	
ECOLI|EnsemblGenome=b2827|UniProtKB=P0A884	P0A884	thyA	PTHR11548:SF9	THYMIDYLATE SYNTHASE 1	THYMIDYLATE SYNTHASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741	nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside monophosphate biosynthetic process#GO:0009124;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;small molecule metabolic process#GO:0044281	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262	Tetrahydrofolate biosynthesis#P02742>Dihydrofolate reductase#P02948;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>Thymidylate synthase#P02913;Formyltetrahydrofolate biosynthesis#P02743>Thymidylate synthase#P02954;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943;Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate reductase#P02957
ECOLI|EnsemblGenome=b2677|UniProtKB=P14175	P14175	proV	PTHR43869:SF1	GLYCINE BETAINE/PROLINE BETAINE TRANSPORT SYSTEM ATP-BINDING PROTEIN PROV	GLYCINE BETAINE_PROLINE BETAINE TRANSPORT SYSTEM ATP-BINDING PROTEIN PROV	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;membrane#GO:0016020;membrane protein complex#GO:0098796;ATP-binding cassette (ABC) transporter complex#GO:0043190;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227	
ECOLI|EnsemblGenome=b0686|UniProtKB=P75736	P75736	ybfF	PTHR46118:SF7	PROTEIN ABHD11	ESTERASE YBFF					
ECOLI|EnsemblGenome=b1956|UniProtKB=P76330	P76330	dgcQ	PTHR45138:SF9	REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM	DIGUANYLATE CYCLASE DGCQ-RELATED	catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772				
ECOLI|EnsemblGenome=b2529|UniProtKB=P0ACD4	P0ACD4	iscU	PTHR10093:SF32	IRON-SULFUR CLUSTER ASSEMBLY ENZYME  NIFU HOMOLOG	IRON-SULFUR CLUSTER ASSEMBLY SCAFFOLD PROTEIN ISCU	cation binding#GO:0043169;iron-sulfur cluster binding#GO:0051536;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;iron ion binding#GO:0005506;ferrous iron binding#GO:0008198	intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	chaperone#PC00072	
ECOLI|EnsemblGenome=b2344|UniProtKB=P10384	P10384	fadL	PTHR35093:SF3	OUTER MEMBRANE PROTEIN NMB0088-RELATED	LONG-CHAIN FATTY ACID TRANSPORT PROTEIN	wide pore channel activity#GO:0022829;channel activity#GO:0015267;monocarboxylic acid transmembrane transporter activity#GO:0008028;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943				
ECOLI|EnsemblGenome=b0756|UniProtKB=P0A9C3	P0A9C3	galM	PTHR10091:SF51	ALDOSE-1-EPIMERASE	ALDOSE 1-EPIMERASE	isomerase activity#GO:0016853;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824	small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;hexose metabolic process#GO:0019318;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glucose metabolic process#GO:0006006;carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	epimerase/racemase#PC00096	
ECOLI|EnsemblGenome=b2136|UniProtKB=P33366	P33366	yohD	PTHR42709:SF2	ALKALINE PHOSPHATASE LIKE PROTEIN	INNER MEMBRANE PROTEIN YOHD		FtsZ-dependent cytokinesis#GO:0043093;cytokinesis#GO:0000910;reproductive process#GO:0022414;reproductive process in single-celled organism#GO:0022413;cell division#GO:0051301;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	phosphatase#PC00181	
ECOLI|EnsemblGenome=b1958|UniProtKB=P46125	P46125	yedI	PTHR30503:SF3	INNER MEMBRANE PROTEIN YEDI	INNER MEMBRANE PROTEIN YEDI			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b2416|UniProtKB=P08839	P08839	ptsI	PTHR46244:SF6	PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE	PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE	phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772	localization#GO:0051179;establishment of localization#GO:0051234;carbohydrate derivative transport#GO:1901264;transport#GO:0006810		protein modifying enzyme#PC00260	
ECOLI|EnsemblGenome=b3183|UniProtKB=P42641	P42641	obgE	PTHR11702:SF39	DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED	GTPASE OBGE_CGTA	binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166				
ECOLI|EnsemblGenome=b0825|UniProtKB=P78055	P78055	fsaA	PTHR10683:SF40	TRANSALDOLASE	FRUCTOSE-6-PHOSPHATE ALDOLASE 1-RELATED				lyase#PC00144;aldolase#PC00044;metabolite interconversion enzyme#PC00262	Pentose phosphate pathway#P02762>Transaldolase#P03081
ECOLI|EnsemblGenome=b3605|UniProtKB=P33232	P33232	lldD	PTHR10578:SF85	S -2-HYDROXY-ACID OXIDASE-RELATED	L-LACTATE DEHYDROGENASE	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491	energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091		oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b4147|UniProtKB=P0A6N4	P0A6N4	efp	PTHR30053:SF12	ELONGATION FACTOR P	ELONGATION FACTOR P (EF-P) FAMILY PROTEIN	translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051		cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	translational protein#PC00263;translation factor#PC00223;translation elongation factor#PC00222	
ECOLI|EnsemblGenome=b1341|UniProtKB=P77302	P77302	dgcM	PTHR45138:SF31	REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM	DIGUANYLATE CYCLASE DGCM-RELATED	catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772	negative regulation of cellular process#GO:0048523;single-species biofilm formation#GO:0044010;cell adhesion#GO:0007155;regulation of cell motility#GO:2000145;cell-substrate adhesion#GO:0031589;negative regulation of biological process#GO:0048519;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of locomotion#GO:0040012;negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;biological regulation#GO:0065007	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b2000|UniProtKB=P39180	P39180	flu	PTHR12338:SF5	AUTOTRANSPORTER	ANTIGEN 43-RELATED				protease#PC00190	
ECOLI|EnsemblGenome=b1450|UniProtKB=P76114	P76114	mcbR	PTHR43537:SF39	TRANSCRIPTIONAL REGULATOR, GNTR FAMILY	HTH-TYPE TRANSCRIPTIONAL REGULATOR MCBR	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110	regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255		helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b1671|UniProtKB=P77375	P77375	ydhX	PTHR43177:SF3	PROTEIN NRFC	PROTEIN NRFC HOMOLOG	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1275|UniProtKB=P0A9F3	P0A9F3	cysB	PTHR30126:SF6	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR CYSB-RELATED	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976	carboxylic acid biosynthetic process#GO:0046394;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;sulfur compound metabolic process#GO:0006790;regulation of primary metabolic process#GO:0080090;amino acid metabolic process#GO:0006520;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;proteinogenic amino acid metabolic process#GO:0170039;regulation of nucleobase-containing compound metabolic process#GO:0019219;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;proteinogenic amino acid biosynthetic process#GO:0170038		gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b1992|UniProtKB=P36561	P36561	cobS	PTHR34148:SF1	ADENOSYLCOBINAMIDE-GDP RIBAZOLETRANSFERASE	ADENOSYLCOBINAMIDE-GDP RIBAZOLETRANSFERASE	phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824	biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;tetrapyrrole biosynthetic process#GO:0033014;cellular process#GO:0009987;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transferase#PC00220;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1648|UniProtKB=P64474	P64474	ydhL	PTHR35175:SF1	DUF1289 DOMAIN-CONTAINING PROTEIN	FE-S PROTEIN					
ECOLI|EnsemblGenome=b4363|UniProtKB=P0ADD2	P0ADD2	yjjB	PTHR34390:SF1	UPF0442 PROTEIN YJJB-RELATED	SUCCINATE TRANSPORTER SUBUNIT YJJB-RELATED		localization#GO:0051179;establishment of localization#GO:0051234;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740;succinate transport#GO:0015744;dicarboxylic acid transport#GO:0006835	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0363|UniProtKB=Q47536	Q47536	yaiP	PTHR43630:SF1	POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE SYNTHASE	POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE SYNTHASE	transferase activity#GO:0016740;catalytic activity#GO:0003824			glycosyltransferase#PC00111	
ECOLI|EnsemblGenome=b3008|UniProtKB=P06721	P06721	metC	PTHR43500:SF1	CYSTATHIONINE BETA-LYASE-RELATED	CYSTATHIONINE BETA-LYASE-RELATED	catalytic activity#GO:0003824;carbon-sulfur lyase activity#GO:0016846;lyase activity#GO:0016829	carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;sulfur compound catabolic process#GO:0044273		metabolite interconversion enzyme#PC00262;lyase#PC00144	Methionine biosynthesis#P02753>Cystathionine lyase#P03025
ECOLI|EnsemblGenome=b0764|UniProtKB=P0AF01	P0AF01	modB	PTHR30183:SF10	MOLYBDENUM TRANSPORT SYSTEM PERMEASE PROTEIN MODB	MOLYBDENUM TRANSPORT SYSTEM PERMEASE PROTEIN MODB	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0545|UniProtKB=P77368	P77368	ybcL	PTHR30289:SF14	UNCHARACTERIZED PROTEIN YBCL-RELATED	UPF0098 PROTEIN YBCL			extracellular region#GO:0005576;periplasmic space#GO:0042597;cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288		
ECOLI|EnsemblGenome=b2240|UniProtKB=P08194	P08194	glpT	PTHR43826:SF6	GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4	GLYCEROL-3-PHOSPHATE TRANSPORTER	active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;carbohydrate derivative transmembrane transporter activity#GO:1901505;organophosphate ester transmembrane transporter activity#GO:0015605;phosphate transmembrane transporter activity#GO:0005315	cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;phosphate ion transport#GO:0006817;organophosphate ester transport#GO:0015748;transport#GO:0006810;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	primary active transporter#PC00068	
ECOLI|EnsemblGenome=b2727|UniProtKB=P0AAN3	P0AAN3	hypB	PTHR30134:SF2	HYDROGENASE PROTEIN ASSEMBLY PROTEIN, NICKEL CHAPERONE	HYDROGENASE MATURATION FACTOR HYPB	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;GTPase activity#GO:0003924;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;cation binding#GO:0043169;catalytic activity#GO:0003824;zinc ion binding#GO:0008270;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111			chaperone#PC00072	
ECOLI|EnsemblGenome=b3868|UniProtKB=P0AFB8	P0AFB8	glnG	PTHR32071:SF95	TRANSCRIPTIONAL REGULATORY PROTEIN	DNA-BINDING TRANSCRIPTIONAL REGULATOR NTRC	sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488	regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794	protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993	DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b2036|UniProtKB=P37747	P37747	glf	PTHR21197:SF0	UDP-GALACTOPYRANOSE MUTASE	UDP-GALACTOPYRANOSE MUTASE	isomerase activity#GO:0016853;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824;anion binding#GO:0043168;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;ion binding#GO:0043167;intramolecular transferase activity#GO:0016866;nucleoside phosphate binding#GO:1901265		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	metabolite interconversion enzyme#PC00262;mutase#PC00160	O-antigen biosynthesis#P02757>UDP-galacto-pyranose mutase#P03048
ECOLI|EnsemblGenome=b3063|UniProtKB=P39414	P39414	ttdT	PTHR42826:SF2	DICARBOXYLATE TRANSPORTER 2.1, CHLOROPLASTIC	CITRATE_SUCCINATE ANTIPORTER-RELATED			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	primary active transporter#PC00068;transporter#PC00227	
ECOLI|EnsemblGenome=b3244|UniProtKB=P0AGG8	P0AGG8	tldD	PTHR30624:SF4	UNCHARACTERIZED PROTEIN TLDD AND PMBA	METALLOPROTEASE TLDD	metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096	cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	protein modifying enzyme#PC00260;protease#PC00190	
ECOLI|EnsemblGenome=b4172|UniProtKB=P0A6X3	P0A6X3	hfq	PTHR34772:SF1	RNA-BINDING PROTEIN HFQ	RNA-BINDING PROTEIN HFQ	binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723	regulation of RNA stability#GO:0043487;regulation of biological quality#GO:0065008;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0405|UniProtKB=P0A7F9	P0A7F9	queA	PTHR30307:SF0	S-ADENOSYLMETHIONINE:TRNA RIBOSYLTRANSFERASE-ISOMERASE	S-ADENOSYLMETHIONINE:TRNA RIBOSYLTRANSFERASE-ISOMERASE	glycosyltransferase activity#GO:0016757;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824	macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA wobble base modification#GO:0002097;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987		metabolite interconversion enzyme#PC00262;isomerase#PC00135	
ECOLI|EnsemblGenome=b0864|UniProtKB=P0AAF6	P0AAF6	artP	PTHR43166:SF25	AMINO ACID IMPORT ATP-BINDING PROTEIN	ARGININE TRANSPORT ATP-BINDING PROTEIN ARTP	primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b1972|UniProtKB=P76343	P76343	msrQ	PTHR36964:SF1	PROTEIN-METHIONINE-SULFOXIDE REDUCTASE HEME-BINDING SUBUNIT MSRQ	PROTEIN-METHIONINE-SULFOXIDE REDUCTASE HEME-BINDING SUBUNIT MSRQ	tetrapyrrole binding#GO:0046906;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;catalytic activity#GO:0003824;oxidoreductase activity, acting on diphenols and related substances as donors#GO:0016679;ribonucleotide binding#GO:0032553;heme binding#GO:0020037		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b2521|UniProtKB=P31142	P31142	sseA	PTHR11364:SF38	THIOSULFATE SULFERTANSFERASE	3-MERCAPTOPYRUVATE SULFURTRANSFERASE	transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783;transferase activity#GO:0016740;catalytic activity#GO:0003824		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	transferase#PC00220	
ECOLI|EnsemblGenome=b3032|UniProtKB=P0AEW4	P0AEW4	cpdA	PTHR12905:SF33	METALLOPHOSPHOESTERASE	3',5'-CYCLIC ADENOSINE MONOPHOSPHATE PHOSPHODIESTERASE CPDA	hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788			metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097	
ECOLI|EnsemblGenome=b0868|UniProtKB=P75821	P75821	ybjS	PTHR43245:SF46	BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA	DEHYDROGENASE					
ECOLI|EnsemblGenome=b0172|UniProtKB=P0A805	P0A805	frr	PTHR20982:SF15	RIBOSOME RECYCLING FACTOR	RIBOSOME-RECYCLING FACTOR	binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;ribosomal large subunit binding#GO:0043023;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022	organelle disassembly#GO:1903008;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;translational termination#GO:0006415;translation#GO:0006412;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;protein-containing complex disassembly#GO:0032984;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;organelle organization#GO:0006996;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	translation release factor#PC00225	
ECOLI|EnsemblGenome=b3617|UniProtKB=P0AB77	P0AB77	kbl	PTHR13693:SF106	CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE	2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE	transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747		intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	transaminase#PC00216	
ECOLI|EnsemblGenome=b0471|UniProtKB=P0A8B5	P0A8B5	ybaB	PTHR33449:SF13	NUCLEOID-ASSOCIATED PROTEIN YBAB	NUCLEOID-ASSOCIATED PROTEIN YBAB	nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677		intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b0308|UniProtKB=P77433	P77433	ykgG	PTHR43682:SF1	LACTATE UTILIZATION PROTEIN C	LACTATE UTILIZATION PROTEIN C	catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b3578|UniProtKB=P37675	P37675	yiaN	PTHR33362:SF4	SIALIC ACID TRAP TRANSPORTER PERMEASE PROTEIN SIAT-RELATED	2,3-DIKETO-L-GULONATE TRAP TRANSPORTER LARGE PERMEASE PROTEIN YIAN	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate transmembrane transporter activity#GO:0015144		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b2926|UniProtKB=P0A799	P0A799	pgk	PTHR11406:SF23	PHOSPHOGLYCERATE KINASE	PHOSPHOGLYCERATE KINASE 1, CHLOROPLASTIC-RELATED	nucleotide binding#GO:0000166;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;phosphoglycerate kinase activity#GO:0004618;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;kinase activity#GO:0016301;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;transferase activity#GO:0016740;carbohydrate derivative binding#GO:0097367;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265	generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate catabolic process#GO:1901292;ADP catabolic process#GO:0046032;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate biosynthetic process#GO:0016051;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;purine nucleotide metabolic process#GO:0006163;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090;small molecule biosynthetic process#GO:0044283;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;purine nucleotide catabolic process#GO:0006195;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine ribonucleotide catabolic process#GO:0009154;hexose biosynthetic process#GO:0019319;nucleoside diphosphate catabolic process#GO:0009134;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;nicotinamide nucleotide metabolic process#GO:0046496;gluconeogenesis#GO:0006094;ATP metabolic process#GO:0046034;oxoacid metabolic process#GO:0043436;ribonucleoside diphosphate metabolic process#GO:0009185;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	carbohydrate kinase#PC00065	Glycolysis#P00024>Phosphoglycerate kinase#P00671
ECOLI|EnsemblGenome=b0110|UniProtKB=P13016	P13016	ampD	PTHR30417:SF4	N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMID	1,6-ANHYDRO-N-ACETYLMURAMYL-L-ALANINE AMIDASE AMPD	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811	metabolic process#GO:0008152;peptidoglycan metabolic process#GO:0000270;aminoglycan metabolic process#GO:0006022;macromolecule metabolic process#GO:0043170;glycosaminoglycan metabolic process#GO:0030203;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;peptidoglycan turnover#GO:0009254	cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;cell wall#GO:0005618;external encapsulating structure#GO:0030312;extracellular region#GO:0005576	hydrolase#PC00121	
ECOLI|EnsemblGenome=b0522|UniProtKB=P09029	P09029	purK	PTHR11609:SF14	PURINE BIOSYNTHESIS PROTEIN 6/7, PUR6/7	BIFUNCTIONAL PURINE SYNTHESIS PROTEIN PURC_E	lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824	primary metabolic process#GO:0044238;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	ligase#PC00142	
ECOLI|EnsemblGenome=b2747|UniProtKB=Q46893	Q46893	ispD	PTHR32125:SF4	2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC	2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC	transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779			transferase#PC00220	
ECOLI|EnsemblGenome=b0083|UniProtKB=P0AEN4	P0AEN4	ftsL	PTHR37479:SF1	CELL DIVISION PROTEIN FTSL	CELL DIVISION PROTEIN FTSL		cell division#GO:0051301;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;reproductive process#GO:0022414;reproductive process in single-celled organism#GO:0022413;FtsZ-dependent cytokinesis#GO:0043093;cytokinesis#GO:0000910	plasma membrane#GO:0005886;cell division site#GO:0032153;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b1987|UniProtKB=Q47083	Q47083	cbl	PTHR30126:SF6	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR CYSB-RELATED	double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;proteinogenic amino acid biosynthetic process#GO:0170038;regulation of biosynthetic process#GO:0009889;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;regulation of nucleobase-containing compound metabolic process#GO:0019219;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;sulfur compound metabolic process#GO:0006790		helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b2624|UniProtKB=P33997	P33997	alpA	PTHR36154:SF1	DNA-BINDING TRANSCRIPTIONAL ACTIVATOR ALPA	DNA-BINDING TRANSCRIPTIONAL ACTIVATOR ALPA				gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b1636|UniProtKB=P77150	P77150	pdxY	PTHR10534:SF2	PYRIDOXAL KINASE	PYRIDOXAL KINASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773	organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;metabolic process#GO:0008152;pyridine-containing compound metabolic process#GO:0072524;small molecule biosynthetic process#GO:0044283;organophosphate biosynthetic process#GO:0090407	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	kinase#PC00137	Pyridoxal phosphate salvage pathway#P02770>Pyridoxamine kinase#P03122;Vitamin B6 metabolism#P02787>Pyridoxal kinase#P03244;Pyridoxal phosphate salvage pathway#P02770>Pyridoxal kinase#P03121
ECOLI|EnsemblGenome=b2501|UniProtKB=P0A7B1	P0A7B1	ppk	PTHR30218:SF0	POLYPHOSPHATE KINASE	POLYPHOSPHATE KINASE	phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740	small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;membrane#GO:0016020	kinase#PC00137	
ECOLI|EnsemblGenome=b1100|UniProtKB=P0AFQ7	P0AFQ7	ycfH	PTHR46124:SF2	D-AMINOACYL-TRNA DEACYLASE	D-AMINOACYL-TRNA DEACYLASE			cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b2198|UniProtKB=P0ABM5	P0ABM5	ccmD	PTHR37531:SF1	HEME EXPORTER PROTEIN D	HEME EXPORTER PROTEIN D		macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170			
ECOLI|EnsemblGenome=b3238|UniProtKB=P64614	P64614	yhcN	PTHR34156:SF5	OUTER MEMBRANE PROTEIN-RELATED-RELATED	EXPORTED PROTEIN		response to stress#GO:0006950;response to stimulus#GO:0050896			
ECOLI|EnsemblGenome=b0970|UniProtKB=P0AAC6	P0AAC6	yccA	PTHR23291:SF115	BAX INHIBITOR-RELATED	MODULATOR OF FTSH PROTEASE YCCA	passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;calcium channel activity#GO:0005262;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267	regulation of proteolysis#GO:0030162;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of biological process#GO:0050789	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227;ion channel#PC00133	
ECOLI|EnsemblGenome=b1516|UniProtKB=P76142	P76142	lsrB	PTHR46847:SF4	D-ALLOSE-BINDING PERIPLASMIC PROTEIN-RELATED	AUTOINDUCER 2-BINDING PROTEIN LSRB		transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179			
ECOLI|EnsemblGenome=b1745|UniProtKB=P76216	P76216	astB	PTHR30420:SF2	N-SUCCINYLARGININE DIHYDROLASE	N-SUCCINYLARGININE DIHYDROLASE	catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;arginine metabolic process#GO:0006525;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987		hydrolase#PC00121;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2323|UniProtKB=P0A953	P0A953	fabB	PTHR11712:SF306	POLYKETIDE SYNTHASE-RELATED	3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1	acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747	cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;monocarboxylic acid biosynthetic process#GO:0072330	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b4021|UniProtKB=P0A7C6	P0A7C6	pepE	PTHR20842:SF0	PROTEASE S51 ALPHA-ASPARTYL DIPEPTIDASE	DIPEPTIDASE E				serine protease#PC00203;protease#PC00190	
ECOLI|EnsemblGenome=b3690|UniProtKB=P31456	P31456	cbrA	PTHR42685:SF22	GERANYLGERANYL DIPHOSPHATE REDUCTASE	CONDITIONED MEDIUM FACTOR RECEPTOR 1				oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0063|UniProtKB=P08204	P08204	araB	PTHR43435:SF4	RIBULOKINASE	FGGY CARBOHYDRATE KINASE DOMAIN-CONTAINING PROTEIN	phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200	small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;primary metabolic process#GO:0044238;monosaccharide metabolic process#GO:0005996;cellular process#GO:0009987	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	transferase#PC00220;carbohydrate kinase#PC00065;metabolite interconversion enzyme#PC00262;kinase#PC00137	Ascorbate degradation#P02729>L-xylulose kinase#P02849;Pentose phosphate pathway#P02762>D-Ribulo Kinase#P03077
ECOLI|EnsemblGenome=b2206|UniProtKB=P33937	P33937	napA	PTHR43105:SF11	RESPIRATORY NITRATE REDUCTASE	PERIPLASMIC NITRATE REDUCTASE	ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491		cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;oxidoreductase complex#GO:1990204;membrane#GO:0016020;catalytic complex#GO:1902494	oxidoreductase#PC00176;reductase#PC00198	
ECOLI|EnsemblGenome=b0314|UniProtKB=P0ABC9	P0ABC9	betT	PTHR30047:SF7	HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN-RELATED	HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b2586|UniProtKB=P46126	P46126	yfiM	PTHR35462:SF2	FAMILY NOT NAMED	TRANSMEMBRANE PROTEIN					
ECOLI|EnsemblGenome=b1345|UniProtKB=P76056	P76056	intR	PTHR30349:SF96	PHAGE INTEGRASE-RELATED	PROPHAGE INTEGRASE INTR-RELATED	catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640	metabolic process#GO:0008152;DNA metabolic process#GO:0006259;chromosome segregation#GO:0007059;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle process#GO:0022402;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139		viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b1379|UniProtKB=P52644	P52644	hslJ	PTHR35535:SF1	HEAT SHOCK PROTEIN HSLJ	HEAT SHOCK PROTEIN HSLJ					
ECOLI|EnsemblGenome=b1020|UniProtKB=P0A9K1	P0A9K1	phoH	PTHR30473:SF3	PROTEIN PHOH	PROTEIN PHOH	nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;ATP binding#GO:0005524;small molecule binding#GO:0036094;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166		cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2009|UniProtKB=P33012	P33012	sbmC	PTHR40055:SF2	TRANSCRIPTIONAL REGULATOR YGIV-RELATED	DNA GYRASE INHIBITOR	enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857	negative regulation of DNA-templated DNA replication#GO:2000104;negative regulation of cellular process#GO:0048523;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA replication#GO:0006275;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255		DNA-binding transcription factor#PC00218	
ECOLI|Gene_OrderedLocusName=b4500|UniProtKB=P76464	P76464	yfaS	PTHR11412:SF199	MACROGLOBULIN / COMPLEMENT	ALPHA-2-MACROGLOBULIN HOMOLOG-RELATED			extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494;extracellular region#GO:0005576;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165	protease inhibitor#PC00191	
ECOLI|EnsemblGenome=b3365|UniProtKB=P08201	P08201	nirB	PTHR43809:SF3	NITRITE REDUCTASE (NADH) LARGE SUBUNIT	NITRITE REDUCTASE (NADH) LARGE SUBUNIT	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	anaerobic respiration#GO:0009061;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;nitrate metabolic process#GO:0042126;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152		oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;reductase#PC00198	
ECOLI|EnsemblGenome=b0855|UniProtKB=P31134	P31134	potG	PTHR42781:SF5	SPERMIDINE/PUTRESCINE IMPORT ATP-BINDING PROTEIN POTA	PUTRESCINE TRANSPORT ATP-BINDING PROTEIN POTG	ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227	
ECOLI|EnsemblGenome=b1658|UniProtKB=P0ACP7	P0ACP7	purR	PTHR30146:SF148	LACI-RELATED TRANSCRIPTIONAL REPRESSOR	HTH-TYPE TRANSCRIPTIONAL REPRESSOR PURR-RELATED	double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355		Lambda repressor-like transcription factor#PC00245;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b4351|UniProtKB=P24202	P24202	mrr	PTHR30015:SF8	MRR RESTRICTION SYSTEM PROTEIN	TYPE IV METHYL-DIRECTED RESTRICTION ENZYME ECOKMRR	DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519		intracellular anatomical structure#GO:0005622;bacterial nucleoid#GO:0043590;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;nucleoid#GO:0009295;cellular anatomical structure#GO:0110165	endodeoxyribonuclease#PC00093	
ECOLI|EnsemblGenome=b2883|UniProtKB=P76641	P76641	guaD	PTHR11271:SF6	GUANINE DEAMINASE	GUANINE DEAMINASE	transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;zinc ion binding#GO:0008270;catalytic activity#GO:0003824;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810	catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;purine nucleobase catabolic process#GO:0006145;purine-containing compound catabolic process#GO:0072523;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	deaminase#PC00088	Purine metabolism#P02769>Guanine Deaminase#P03118;Xanthine and guanine salvage pathway#P02788>Guanine deaminase#P03249
ECOLI|EnsemblGenome=b3026|UniProtKB=P40719	P40719	qseC	PTHR45436:SF14	SENSOR HISTIDINE KINASE YKOH	SENSOR PROTEIN QSEC		phosphorelay signal transduction system#GO:0000160;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;intracellular signal transduction#GO:0035556	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transmembrane signal receptor#PC00197;histidine kinase receptor of two-component system#PC00265	
ECOLI|EnsemblGenome=b3916|UniProtKB=P0A796	P0A796	pfkA	PTHR13697:SF4	PHOSPHOFRUCTOKINASE	ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE	kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;carbohydrate derivative binding#GO:0097367;carbohydrate kinase activity#GO:0019200;phosphotransferase activity, alcohol group as acceptor#GO:0016773;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167	purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide catabolic process#GO:0006195;pyridine-containing compound metabolic process#GO:0072524;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate metabolic process#GO:0005975;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139	intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829	transferase#PC00220;kinase#PC00137;carbohydrate kinase#PC00065	Glycolysis#P00024>Phosphofructokinase-1#P00672
ECOLI|EnsemblGenome=b0316|UniProtKB=P77700	P77700	yahB	PTHR30126:SF18	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR PUNR	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976	regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355		gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b4345|UniProtKB=P15006	P15006	mcrC	PTHR38733:SF1	PROTEIN MCRC	TYPE IV METHYL-DIRECTED RESTRICTION ENZYME ECOKMCRBC	hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520		intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;endonuclease complex#GO:1905348		
ECOLI|EnsemblGenome=b2937|UniProtKB=P60651	P60651	speB	PTHR11358:SF44	ARGINASE/AGMATINASE	AGMATINASE	catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810	biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;polyamine biosynthetic process#GO:0006596;polyamine metabolic process#GO:0006595;cellular process#GO:0009987;metabolic process#GO:0008152;amine metabolic process#GO:0009308	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	hydrolase#PC00121	
ECOLI|EnsemblGenome=b3271|UniProtKB=P45769	P45769	yhdZ	PTHR43166:SF4	AMINO ACID IMPORT ATP-BINDING PROTEIN	GLUTAMINE TRANSPORT ATP-BINDING PROTEIN GLNQ	ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b3733|UniProtKB=P0ABA6	P0ABA6	atpG	PTHR11693:SF47	ATP SYNTHASE GAMMA CHAIN	ATP SYNTHASE GAMMA CHAIN	catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;proton channel activity#GO:0015252;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933	purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside phosphate biosynthetic process#GO:1901293;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;ATP biosynthetic process#GO:0006754;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522	cation channel complex#GO:0034703;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;respiratory chain complex#GO:0098803;proton-transporting ATP synthase complex#GO:0045259;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702	ATP synthase#PC00002	ATP synthesis#P02721>F1 gamma#P02796
ECOLI|EnsemblGenome=b3954|UniProtKB=P32677	P32677	yijO	PTHR43280:SF10	ARAC-FAMILY TRANSCRIPTIONAL REGULATOR	TRANSCRIPTIONAL REGULATOR	DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789		helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b1406|UniProtKB=P25906	P25906	pdxI	PTHR43625:SF40	AFLATOXIN B1 ALDEHYDE REDUCTASE	ALDO-KETO REDUCTASE YAKC [NADP(+)]	catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614		cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	oxidoreductase#PC00176;reductase#PC00198	
ECOLI|EnsemblGenome=b2350|UniProtKB=P77682	P77682	yfdG	PTHR38459:SF1	PROPHAGE BACTOPRENOL-LINKED GLUCOSE TRANSLOCASE HOMOLOG	PROPHAGE BACTOPRENOL-LINKED GLUCOSE TRANSLOCASE HOMOLOG			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b2597|UniProtKB=P0AD49	P0AD49	raiA	PTHR33231:SF3	30S RIBOSOMAL PROTEIN	RIBOSOME-ASSOCIATED INHIBITOR A	translation regulator activity#GO:0045182	regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;developmental process#GO:0032502;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of translation#GO:0017148;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b2196|UniProtKB=P33927	P33927	ccmF	PTHR43653:SF5	CYTOCHROME C ASSEMBLY PROTEIN-RELATED	CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCMF			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	chaperone#PC00072	
ECOLI|EnsemblGenome=b2492|UniProtKB=P77733	P77733	focB	PTHR30520:SF10	FORMATE TRANSPORTER-RELATED	FORMATE CHANNEL FOCA-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;secondary active transmembrane transporter activity#GO:0015291;monocarboxylic acid transmembrane transporter activity#GO:0008028;nitrate transmembrane transporter activity#GO:0015112;active transmembrane transporter activity#GO:0022804	nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;localization#GO:0051179;monocarboxylic acid transport#GO:0015718;inorganic anion transport#GO:0015698;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b1784|UniProtKB=P76235	P76235	yeaH	PTHR30510:SF2	UPF0229 PROTEIN YEAH	UPF0229 PROTEIN YEAH					
ECOLI|EnsemblGenome=b3385|UniProtKB=P32662	P32662	gph	PTHR43434:SF1	PHOSPHOGLYCOLATE PHOSPHATASE	PHOSPHOGLYCOLATE PHOSPHATASE	catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578	nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152		phosphatase#PC00181;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0077|UniProtKB=P00893	P00893	ilvI	PTHR18968:SF13	THIAMINE PYROPHOSPHATE ENZYMES	ACETOLACTATE SYNTHASE CATALYTIC SUBUNIT, MITOCHONDRIAL	nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;small molecule binding#GO:0036094;transketolase or transaldolase activity#GO:0016744;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363	proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;branched-chain amino acid biosynthetic process#GO:0009082;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;catalytic complex#GO:1902494	metabolite interconversion enzyme#PC00262;ligase#PC00142	Valine biosynthesis#P02785>Acetolactate synthase#P03216;Isoleucine biosynthesis#P02748>Acetolactate synthase#P02997
ECOLI|EnsemblGenome=b1917|UniProtKB=P37774	P37774	tcyN	PTHR43166:SF9	AMINO ACID IMPORT ATP-BINDING PROTEIN	L-CYSTINE TRANSPORT SYSTEM ATP-BINDING PROTEIN TCYN	ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227	
ECOLI|EnsemblGenome=b2268|UniProtKB=P0A8V0	P0A8V0	rbn	PTHR46018:SF8	ZINC PHOSPHODIESTERASE ELAC PROTEIN 1	RIBONUCLEASE BN	hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787			phosphodiesterase#PC00185	
ECOLI|EnsemblGenome=b3455|UniProtKB=P0A9S7	P0A9S7	livG	PTHR45772:SF11	CONSERVED COMPONENT OF ABC TRANSPORTER FOR NATURAL AMINO ACIDS-RELATED	HIGH-AFFINITY BRANCHED-CHAIN AMINO ACID TRANSPORT ATP-BINDING PROTEIN LIVG	neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;branched-chain amino acid transmembrane transporter activity#GO:0015658;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179;carboxylic acid transmembrane transporter activity#GO:0046943;aromatic amino acid transmembrane transporter activity#GO:0015173	amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;localization#GO:0051179;L-alpha-amino acid transmembrane transport#GO:1902475;import across plasma membrane#GO:0098739;carboxylic acid transmembrane transport#GO:1905039;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;alanine transport#GO:0032328;establishment of localization#GO:0051234;import into cell#GO:0098657;branched-chain amino acid transport#GO:0015803;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227;primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b1394|UniProtKB=P77467	P77467	paaG	PTHR11941:SF133	ENOYL-COA HYDRATASE-RELATED	1,2-EPOXYPHENYLACETYL-COA ISOMERASE		fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;lipid modification#GO:0030258;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282		metabolite interconversion enzyme#PC00262;hydratase#PC00120;lyase#PC00144	
ECOLI|EnsemblGenome=b2232|UniProtKB=P17993	P17993	ubiG	PTHR43464:SF100	METHYLTRANSFERASE	UBIQUINONE BIOSYNTHESIS O-METHYLTRANSFERASE	methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824			methyltransferase#PC00155;transferase#PC00220	
ECOLI|EnsemblGenome=b3339|UniProtKB=P0CE47	P0CE47	tufA	PTHR43721:SF22	ELONGATION FACTOR TU-RELATED	ELONGATION FACTOR TU 1-RELATED	translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051	protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;translational elongation#GO:0006414;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238		translation elongation factor#PC00222	
ECOLI|EnsemblGenome=b2423|UniProtKB=P0AEB0	P0AEB0	cysW	PTHR30406:SF9	SULFATE TRANSPORT SYSTEM PERMEASE PROTEIN	SULFATE TRANSPORT SYSTEM PERMEASE PROTEIN CYSW			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b2319|UniProtKB=P08390	P08390	usg	PTHR46278:SF2	DEHYDROGENASE, PUTATIVE-RELATED	USG-1 PROTEIN	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491	proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;L-lysine biosynthetic process#GO:0009085;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;aspartate family amino acid biosynthetic process#GO:0009067;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	Threonine biosynthesis#P02781>Aspartate semialdehyde dehydrogenase#P03192;Lysine biosynthesis#P02751>Aspartate semialdehyde dehydrogenase#P03013
ECOLI|EnsemblGenome=b4051|UniProtKB=P28304	P28304	qorA	PTHR48106:SF13	QUINONE OXIDOREDUCTASE PIG3-RELATED	ZETA-CRYSTALLIN	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;mRNA 3'-UTR binding#GO:0003730;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729		cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	Huntington disease#P00029>PIG3#G01535
ECOLI|EnsemblGenome=b4331|UniProtKB=P39380	P39380	kptA	PTHR12684:SF3	PUTATIVE PHOSPHOTRANSFERASE	RNA 2'-PHOSPHOTRANSFERASE	catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101	gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187		transferase#PC00220;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1486|UniProtKB=P77308	P77308	ddpB	PTHR43163:SF8	DIPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN DPPB-RELATED	D,D-DIPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN DDPB-RELATED	oligopeptide transmembrane transporter activity#GO:0035673;dipeptide transmembrane transporter activity#GO:0071916;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b2121|UniProtKB=P33352	P33352	yehP	PTHR30634:SF16	OUTER MEMBRANE LOLAB LIPOPROTEIN INSERTION APPARATUS	OUTER-MEMBRANE LIPOPROTEIN LOLB				transporter#PC00227	
ECOLI|EnsemblGenome=b4258|UniProtKB=P07118	P07118	valS	PTHR11946:SF93	VALYL-TRNA SYNTHETASES	VALINE--TRNA LIGASE-RELATED	catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101	primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170		aminoacyl-tRNA synthetase#PC00047	
ECOLI|EnsemblGenome=b2032|UniProtKB=P37751	P37751	wbbK	PTHR46401:SF2	GLYCOSYLTRANSFERASE WBBK-RELATED	GLYCOSYLTRANSFERASE WBBK-RELATED	catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757	primary metabolic process#GO:0044238;lipopolysaccharide biosynthetic process#GO:0009103;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;liposaccharide metabolic process#GO:1903509;polysaccharide biosynthetic process#GO:0000271;lipopolysaccharide metabolic process#GO:0008653;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170		glycosyltransferase#PC00111	
ECOLI|EnsemblGenome=b2261|UniProtKB=P29208	P29208	menC	PTHR48073:SF8	O-SUCCINYLBENZOATE SYNTHASE-RELATED	O-SUCCINYLBENZOATE SYNTHASE	hydro-lyase activity#GO:0016836;isomerase activity#GO:0016853;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824	peptide metabolic process#GO:0006518;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;menaquinone biosynthetic process#GO:0009234;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181			
ECOLI|EnsemblGenome=b4105|UniProtKB=P16682	P16682	phnD	PTHR30043:SF10	PHOSPHONATES TRANSPORT SYSTEM PERMEASE PROTEIN	PHOSPHONATES-BINDING PERIPLASMIC PROTEIN					
ECOLI|EnsemblGenome=b0636|UniProtKB=P0A8I8	P0A8I8	rlmH	PTHR33603:SF1	METHYLTRANSFERASE	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE H	S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649	RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA base methylation#GO:0070475;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467		methyltransferase#PC00155;transferase#PC00220	
ECOLI|EnsemblGenome=b2561|UniProtKB=P37767	P37767	yfhH	PTHR30514:SF17	GLUCOKINASE	HTH-TYPE TRANSCRIPTIONAL REGULATOR MURR	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355	protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993	kinase#PC00137	
ECOLI|EnsemblGenome=b0506|UniProtKB=P0ACN4	P0ACN4	allR	PTHR30136:SF24	HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY	HTH-TYPE TRANSCRIPTIONAL REPRESSOR ALLR	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b1449|UniProtKB=P76113	P76113	curA	PTHR43205:SF7	PROSTAGLANDIN REDUCTASE	PROSTAGLANDIN REDUCTASE 1-RELATED	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824			reductase#PC00198	
ECOLI|EnsemblGenome=b2041|UniProtKB=P37759	P37759	rfbB	PTHR43000:SF55	DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED	DTDP-GLUCOSE 4,6-DEHYDRATASE 1	carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824			dehydratase#PC00091	O-antigen biosynthesis#P02757>dTDP-glucose 4,6-dehydratase#P03045
ECOLI|EnsemblGenome=b2493|UniProtKB=P0AFI9	P0AFI9	perM	PTHR21716:SF53	TRANSMEMBRANE PROTEIN	PERMEASE PERM-RELATED		transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic hydroxy compound transport#GO:0015850	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b2736|UniProtKB=Q46888	Q46888	ltnD	PTHR43060:SF17	3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED	L-THREONATE DEHYDROGENASE	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824			oxidoreductase#PC00176;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b1682|UniProtKB=P77499	P77499	sufC	PTHR43204:SF1	ABC TRANSPORTER I FAMILY MEMBER 6, CHLOROPLASTIC	ATP-DEPENDENT TRANSPORTER SUFC-RELATED	ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818	cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;iron-sulfur cluster assembly#GO:0016226	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165	transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b3445|UniProtKB=P0CF29	P0CF29	insB6	PTHR33293:SF1	INSERTION ELEMENT IS1 1 PROTEIN INSB-RELATED	INSERTION ELEMENT IS1 1 PROTEIN INSB-RELATED					
ECOLI|EnsemblGenome=b3220|UniProtKB=P45423	P45423	yhcG	PTHR30547:SF5	UNCHARACTERIZED PROTEIN YHCG-RELATED	NUCLEASE YHCG-RELATED					
ECOLI|EnsemblGenome=b2729|UniProtKB=P24192	P24192	hypD	PTHR30149:SF0	HYDROGENASE PROTEIN ASSEMBLY PROTEIN HYPD	HYDROGENASE MATURATION FACTOR HYPD	iron ion binding#GO:0005506;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;iron-sulfur cluster binding#GO:0051536;cation binding#GO:0043169;metal ion binding#GO:0046872	protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059		chaperone#PC00072	
ECOLI|EnsemblGenome=b1094|UniProtKB=P0A6A8	P0A6A8	acpP	PTHR20863:SF76	ACYL CARRIER PROTEIN	ACYL CARRIER PROTEIN	small molecule binding#GO:0036094;binding#GO:0005488;molecular carrier activity#GO:0140104	lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;lipid A biosynthetic process#GO:0009245;liposaccharide metabolic process#GO:1903509;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	transfer/carrier protein#PC00219	
ECOLI|EnsemblGenome=b3407|UniProtKB=P46837	P46837	yhgF	PTHR10724:SF13	30S RIBOSOMAL PROTEIN S1	PROTEIN YHGF	mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;RNA binding#GO:0003723	macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b0992|UniProtKB=P52636	P52636	yccM	PTHR30224:SF4	ELECTRON TRANSPORT PROTEIN	ELECTRON TRANSPORT PROTEIN YCCM-RELATED			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b2684|UniProtKB=P0ACR9	P0ACR9	mprA	PTHR33164:SF56	TRANSCRIPTIONAL REGULATOR, MARR FAMILY	TRANSCRIPTIONAL REPRESSOR MPRA		regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141		winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b3258|UniProtKB=P16256	P16256	panF	PTHR48086:SF4	SODIUM/PROLINE SYMPORTER-RELATED	SODIUM_PANTOTHENATE SYMPORTER	monocarboxylic acid transmembrane transporter activity#GO:0008028;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215	organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;carboxylic acid transmembrane transport#GO:1905039;vitamin transport#GO:0051180	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	primary active transporter#PC00068	
ECOLI|EnsemblGenome=b2530|UniProtKB=P0A6B7	P0A6B7	iscS	PTHR11601:SF34	CYSTEINE DESULFURYLASE FAMILY MEMBER	CYSTEINE DESULFURASE ISCS				lyase#PC00144;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1210|UniProtKB=P0A6X1	P0A6X1	hemA	PTHR43013:SF1	GLUTAMYL-TRNA REDUCTASE	GLUTAMYL-TRNA REDUCTASE	oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101	metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;cellular process#GO:0009987;tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058		translational protein#PC00263	
ECOLI|EnsemblGenome=b2893|UniProtKB=P0AEG6	P0AEG6	dsbC	PTHR35272:SF3	THIOL:DISULFIDE INTERCHANGE PROTEIN DSBC-RELATED	THIOL:DISULFIDE INTERCHANGE PROTEIN DSBC	catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756;intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853	protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059	cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;periplasmic space#GO:0042597		
ECOLI|EnsemblGenome=b3295|UniProtKB=P0A7Z4	P0A7Z4	rpoA	PTHR32108:SF13	DNA-DIRECTED RNA POLYMERASE SUBUNIT ALPHA	DNA-DIRECTED RNA POLYMERASE SUBUNIT ALPHA			cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	DNA-directed RNA polymerase#PC00019	
ECOLI|EnsemblGenome=b2476|UniProtKB=P0A7D7	P0A7D7	purC	PTHR43599:SF3	MULTIFUNCTIONAL PROTEIN ADE2	BIFUNCTIONAL PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE_PHOSPHORIBOSYLAMINOIMIDAZOLE SUCCINOCARBOXAMIDE SYNTHETASE	catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879	purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;IMP metabolic process#GO:0046040;primary metabolic process#GO:0044238;IMP biosynthetic process#GO:0006188;organophosphate biosynthetic process#GO:0090407;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside phosphate biosynthetic process#GO:1901293	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b2566|UniProtKB=P06616	P06616	era	PTHR42698:SF3	GTPASE ERA	GTPASE ERA		cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;ribosomal small subunit biogenesis#GO:0042274;ribonucleoprotein complex biogenesis#GO:0022613;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein-RNA complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosome assembly#GO:0042255		RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b1661|UniProtKB=P0A9H7	P0A9H7	cfa	PTHR43667:SF1	CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE	CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE	S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;catalytic activity#GO:0003824;transferase activity#GO:0016740	cellular process#GO:0009987;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610		methyltransferase#PC00155	
ECOLI|EnsemblGenome=b1761|UniProtKB=P00370	P00370	gdhA	PTHR43571:SF1	NADP-SPECIFIC GLUTAMATE DEHYDROGENASE 1-RELATED	NADP-SPECIFIC GLUTAMATE DEHYDROGENASE 1-RELATED	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	dehydrogenase#PC00092	Glutamine glutamate conversion#P02745>Glutamate Dehydrogenase#P02967
ECOLI|EnsemblGenome=b2474|UniProtKB=P76562	P76562	tmcA	PTHR10925:SF8	N-ACETYLTRANSFERASE 10	TRNA(MET) CYTIDINE ACETYLTRANSFERASE TMCA	catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on RNA#GO:0140098;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a tRNA#GO:0140101	ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA modification#GO:0000154;tRNA wobble base modification#GO:0002097;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;ribonucleoprotein complex biogenesis#GO:0022613		RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b3306|UniProtKB=P0A7W7	P0A7W7	rpsH	PTHR11758:SF4	40S RIBOSOMAL PROTEIN S15A	SMALL RIBOSOMAL SUBUNIT PROTEIN US8	structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735		protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229	translational protein#PC00263;ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b3700|UniProtKB=P0A7H0	P0A7H0	recF	PTHR32182:SF0	DNA REPLICATION AND REPAIR PROTEIN RECF	DNA REPLICATION AND REPAIR PROTEIN RECF		macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA repair#GO:0006281;metabolic process#GO:0008152;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;recombinational repair#GO:0000725		DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b0399|UniProtKB=P0AFJ5	P0AFJ5	phoB	PTHR48111:SF40	REGULATOR OF RPOS	PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN PHOB	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;molecular transducer activity#GO:0060089;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976	regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993	helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b2420|UniProtKB=P78271	P78271	yfeS	PTHR30634:SF13	OUTER MEMBRANE LOLAB LIPOPROTEIN INSERTION APPARATUS	PROTEIN YEHF				transporter#PC00227	
ECOLI|EnsemblGenome=b1316|UniProtKB=P77154	P77154	ycjT	PTHR11051:SF8	GLYCOSYL HYDROLASE-RELATED	MIP16835P1	hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824	cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975		glycosidase#PC00110;hydrolase#PC00121	
ECOLI|EnsemblGenome=b1650|UniProtKB=P77258	P77258	nemA	PTHR22893:SF142	NADH OXIDOREDUCTASE-RELATED	N-ETHYLMALEIMIDE REDUCTASE				metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3151|UniProtKB=P45468	P45468	yraQ	PTHR43299:SF1	UPF0718 PROTEIN YRAQ	UPF0718 PROTEIN YRAQ			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b0372|UniProtKB=P0CF80	P0CF80	insF2	PTHR46889:SF4	TRANSPOSASE INSF FOR INSERTION SEQUENCE IS3B-RELATED	TRANSPOSASE INSF FOR INSERTION SEQUENCE IS3B				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b0872|UniProtKB=P75824	P75824	hcr	PTHR47354:SF6	NADH OXIDOREDUCTASE HCR	NADH OXIDOREDUCTASE HCR	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2840|UniProtKB=P03813	P03813	ygeA	PTHR21198:SF7	GLUTAMATE RACEMASE	ASPARTATE-GLUTAMATE RACEMASE FAMILY	isomerase activity#GO:0016853;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854				
ECOLI|EnsemblGenome=b2600|UniProtKB=P07023	P07023	tyrA	PTHR21363:SF0	PREPHENATE DEHYDROGENASE	PREPHENATE DEHYDROGENASE [NADP(+)]	catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491	small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;aromatic amino acid biosynthetic process#GO:0009073;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039		dehydrogenase#PC00092;oxidoreductase#PC00176	Tyrosine biosynthesis#P02784>Prephenate dehydrogenase#P03214
ECOLI|EnsemblGenome=b4195|UniProtKB=P69820	P69820	ulaC	PTHR36203:SF1	ASCORBATE-SPECIFIC PTS SYSTEM EIIA COMPONENT	ASCORBATE-SPECIFIC PTS SYSTEM EIIA COMPONENT	active transmembrane transporter activity#GO:0022804;transferase activity, transferring phosphorus-containing groups#GO:0016772;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate transmembrane transporter activity#GO:0015144;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein-phosphocysteine-sugar phosphotransferase activity#GO:0090563	phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;transmembrane transport#GO:0055085;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;carbohydrate transport#GO:0008643;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739;cellular process#GO:0009987			
ECOLI|EnsemblGenome=b2039|UniProtKB=P37744	P37744	rfbA	PTHR43532:SF1	GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE	GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE 1	catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772	macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;polysaccharide biosynthetic process#GO:0000271;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	metabolite interconversion enzyme#PC00262;nucleotidyltransferase#PC00174	O-antigen biosynthesis#P02757>dTDP-glucose pyrophosphorylase#P03046
ECOLI|Gene_OrderedLocusName=JW2016|UniProtKB=P36667	P36667	wbbL	PTHR43179:SF7	RHAMNOSYLTRANSFERASE WBBL	RHAMNOSYLTRANSFERASE WBBL	glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740	polysaccharide metabolic process#GO:0005976;carbohydrate biosynthetic process#GO:0016051;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;polysaccharide biosynthetic process#GO:0000271		glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262;transferase#PC00220	
ECOLI|EnsemblGenome=b3137|UniProtKB=P0AB74	P0AB74	kbaY	PTHR30304:SF12	D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE	D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE SUBUNIT GATY-RELATED	carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	aldolase#PC00044;lyase#PC00144	
ECOLI|EnsemblGenome=b0307|UniProtKB=P77536	P77536	ykgF	PTHR47153:SF2	LACTATE UTILIZATION PROTEIN B	LACTATE UTILIZATION PROTEIN B	oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824	oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752			
ECOLI|EnsemblGenome=b2395|UniProtKB=P23842	P23842	pdeA	PTHR33121:SF74	CYCLIC DI-GMP PHOSPHODIESTERASE PDEF	CYCLIC DI-GMP PHOSPHODIESTERASE PDEA-RELATED	hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787	regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular process#GO:0050794	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185	
ECOLI|EnsemblGenome=b3487|UniProtKB=P37626	P37626	yhiI	PTHR30438:SF2	36 KDA ANTIGEN-RELATED	EFFLUX PUMP, RND FAMILY, MEMBRANE FUSION PROTEIN			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b0980|UniProtKB=P07102	P07102	appA	PTHR11567:SF212	ACID PHOSPHATASE-RELATED	PHYTASE APPA	phosphatase activity#GO:0016791;sugar-phosphatase activity#GO:0050308;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578		extracellular region#GO:0005576;periplasmic space#GO:0042597;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;cell envelope#GO:0030313	phosphatase#PC00181	
ECOLI|EnsemblGenome=b1384|UniProtKB=Q47129	Q47129	feaR	PTHR46796:SF10	HTH-TYPE TRANSCRIPTIONAL ACTIVATOR RHAS-RELATED	TRANSCRIPTIONAL ACTIVATOR FEAR	transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889		helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b0116|UniProtKB=P0A9P0	P0A9P0	lpdA	PTHR22912:SF160	DISULFIDE OXIDOREDUCTASE	DIHYDROLIPOYL DEHYDROGENASE	oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;binding#GO:0005488;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;catalytic activity#GO:0003824	small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;monocarboxylic acid metabolic process#GO:0032787;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987		oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0581|UniProtKB=P77213	P77213	ybdK	PTHR36510:SF1	GLUTAMATE--CYSTEINE LIGASE 2-RELATED	GLUTAMATE--CYSTEINE LIGASE 2-RELATED	ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874			ligase#PC00142	
ECOLI|EnsemblGenome=b1738|UniProtKB=P69795	P69795	chbB	PTHR34581:SF2	PTS SYSTEM N,N'-DIACETYLCHITOBIOSE-SPECIFIC EIIB COMPONENT	PTS SYSTEM N,N'-DIACETYLCHITOBIOSE-SPECIFIC EIIB COMPONENT	protein-phosphocysteine-sugar phosphotransferase activity#GO:0090563;carbohydrate transmembrane transporter activity#GO:0015144;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;transferase activity#GO:0016740;active transmembrane transporter activity#GO:0022804	cellular process#GO:0009987;import across plasma membrane#GO:0098739;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643;transport#GO:0006810;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;localization#GO:0051179;import into cell#GO:0098657;transmembrane transport#GO:0055085;establishment of localization#GO:0051234			
ECOLI|EnsemblGenome=b2557|UniProtKB=P15254	P15254	purL	PTHR10099:SF1	PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE	PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE	ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879	nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165		De novo purine biosynthesis#P02738>Phosphoribosylformylglycinamide  synthase#P02898
ECOLI|EnsemblGenome=b0954|UniProtKB=P0A6Q3	P0A6Q3	fabA	PTHR30272:SF8	3-HYDROXYACYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE	3-HYDROXYDECANOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE	lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824	monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	dehydratase#PC00091	
ECOLI|EnsemblGenome=b1223|UniProtKB=P10903	P10903	narK	PTHR23515:SF9	HIGH-AFFINITY NITRATE TRANSPORTER 2.3	NITRATE_NITRITE ANTIPORTER NARK				transporter#PC00227	
ECOLI|EnsemblGenome=b2909|UniProtKB=P0A8C4	P0A8C4	ygfB	PTHR37528:SF1	UPF0149 PROTEIN YGFB	UPF0149 PROTEIN YGFB			cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b2503|UniProtKB=P77172	P77172	pdeF	PTHR33121:SF64	CYCLIC DI-GMP PHOSPHODIESTERASE PDEF	CYCLIC DI-GMP PHOSPHODIESTERASE PDEF	hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578	regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular process#GO:0050794	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262;hydrolase#PC00121	
ECOLI|EnsemblGenome=b0782|UniProtKB=P0AEZ9	P0AEZ9	moaB	PTHR43232:SF2	MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN B	MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN B			cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b0674|UniProtKB=P22106	P22106	asnB	PTHR11772:SF2	ASPARAGINE SYNTHETASE	ASPARAGINE SYNTHETASE B [GLUTAMINE-HYDROLYZING]	ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879	primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;aspartate family amino acid biosynthetic process#GO:0009067;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038		ligase#PC00142	Asparagine and aspartate biosynthesis#P02730>Asparagine synthetase#P02853
ECOLI|EnsemblGenome=b4049|UniProtKB=P32695	P32695	dusA	PTHR42907:SF9	FMN-LINKED OXIDOREDUCTASES SUPERFAMILY PROTEIN	TRNA-DIHYDROURIDINE(20_20A) SYNTHASE	catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824	RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3879|UniProtKB=P32139	P32139	yihR	PTHR10091:SF0	ALDOSE-1-EPIMERASE	GALACTOSE MUTAROTASE	racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;isomerase activity#GO:0016853	carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate catabolic process#GO:0016052;glucose metabolic process#GO:0006006;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996		epimerase/racemase#PC00096	
ECOLI|EnsemblGenome=b0994|UniProtKB=P38683	P38683	torT	PTHR30146:SF60	LACI-RELATED TRANSCRIPTIONAL REPRESSOR	PERIPLASMIC PROTEIN TORT	nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222		Lambda repressor-like transcription factor#PC00245;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b0892|UniProtKB=P0AAZ4	P0AAZ4	rarA	PTHR13779:SF8	WERNER HELICASE-INTERACTING PROTEIN 1 FAMILY MEMBER	REPLICATION-ASSOCIATED RECOMBINATION PROTEIN A	ATP-dependent activity#GO:0140657;enzyme regulator activity#GO:0030234;ATP-dependent activity, acting on DNA#GO:0008094;molecular function activator activity#GO:0140677;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;enzyme activator activity#GO:0008047;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;molecular function regulator activity#GO:0098772	response to stimulus#GO:0050896;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated DNA replication#GO:0006261;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259		DNA metabolism protein#PC00009;DNA helicase#PC00011	
ECOLI|EnsemblGenome=b2312|UniProtKB=P0AG16	P0AG16	purF	PTHR11907:SF28	AMIDOPHOSPHORIBOSYLTRANSFERASE	AMIDOPHOSPHORIBOSYLTRANSFERASE	glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824	nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	metabolite interconversion enzyme#PC00262;transferase#PC00220	De novo purine biosynthesis#P02738>Amidophosphoribosyl transferase#P02905
ECOLI|EnsemblGenome=b0998|UniProtKB=P36662	P36662	torD	PTHR34227:SF11	CHAPERONE PROTEIN YCDY	CHAPERONE PROTEIN TORD		macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	chaperone#PC00072	
ECOLI|EnsemblGenome=b3838|UniProtKB=P69425	P69425	tatB	PTHR33162:SF1	SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATA, CHLOROPLASTIC	SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATA, CHLOROPLASTIC	active transmembrane transporter activity#GO:0022804;transmembrane protein transporter activity#GO:0008320;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein transmembrane transport#GO:0065002			
ECOLI|EnsemblGenome=b3801|UniProtKB=P25549	P25549	aslA	PTHR42693:SF53	ARYLSULFATASE FAMILY MEMBER	SULFATASE ASLA-RELATED	hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824			hydrolase#PC00121	
ECOLI|EnsemblGenome=b1396|UniProtKB=P76084	P76084	paaI	PTHR42856:SF1	ACYL-COENZYME A THIOESTERASE PAAI	ACYL-COENZYME A THIOESTERASE PAAI	hydrolase activity#GO:0016787;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;deacylase activity#GO:0160215;acyl-CoA hydrolase activity#GO:0016289;catalytic activity#GO:0003824			esterase#PC00097	
ECOLI|EnsemblGenome=b0925|UniProtKB=P22525	P22525	ycbB	PTHR41533:SF1	L,D-TRANSPEPTIDASE HI_1667-RELATED	L,D-TRANSPEPTIDASE YCBB-RELATED	serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233	peptidoglycan-based cell wall biogenesis#GO:0009273;peptidoglycan metabolic process#GO:0000270;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;glycosaminoglycan biosynthetic process#GO:0006024;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;cell wall macromolecule biosynthetic process#GO:0044038;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;cell wall organization or biogenesis#GO:0071554;aminoglycan metabolic process#GO:0006022;cell wall macromolecule metabolic process#GO:0044036;cell wall biogenesis#GO:0042546;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan metabolic process#GO:0030203;peptidoglycan biosynthetic process#GO:0009252		protease#PC00190	
ECOLI|EnsemblGenome=b3709|UniProtKB=P23173	P23173	tnaB	PTHR46997:SF1	LOW AFFINITY TRYPTOPHAN PERMEASE-RELATED	LOW AFFINITY TRYPTOPHAN PERMEASE-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	cellular process#GO:0009987;transport#GO:0006810;amino acid transport#GO:0006865;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2278|UniProtKB=P33607	P33607	nuoL	PTHR42829:SF3	NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5	NADH-QUINONE OXIDOREDUCTASE SUBUNIT L		monoatomic cation transport#GO:0006812;localization#GO:0051179;proton transmembrane transport#GO:1902600;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271	oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1766|UniProtKB=P08395	P08395	sppA	PTHR33209:SF3	PROTEASE 4	PEPTIDASE S49 DOMAIN-CONTAINING PROTEIN				protease#PC00190;serine protease#PC00203	
ECOLI|EnsemblGenome=b2768|UniProtKB=Q46906	Q46906	ygcP	PTHR35787:SF1	GLYCEROL UPTAKE OPERON ANTITERMINATOR REGULATORY PROTEIN	ANTI-TERMINATOR REGULATORY PROTEIN YGCP-RELATED					
ECOLI|EnsemblGenome=b1897|UniProtKB=P31678	P31678	otsB	PTHR43768:SF3	TREHALOSE 6-PHOSPHATE PHOSPHATASE	TREHALOSE 6-PHOSPHATE PHOSPHATASE				hydrolase#PC00121;phosphatase#PC00181	
ECOLI|EnsemblGenome=b0731|UniProtKB=P54745	P54745	mngA	PTHR30505:SF28	FRUCTOSE-LIKE PERMEASE	PTS SYSTEM 2-O-ALPHA-MANNOSYL-D-GLYCERATE-SPECIFIC EIIABC COMPONENT	active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate transmembrane transporter activity#GO:0015144;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein-phosphocysteine-sugar phosphotransferase activity#GO:0090563	import across plasma membrane#GO:0098739;carbohydrate transmembrane transport#GO:0034219;cellular process#GO:0009987;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;import into cell#GO:0098657;carbohydrate transport#GO:0008643;transport#GO:0006810	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b0741|UniProtKB=P0A912	P0A912	pal	PTHR30128:SF86	OUTER MEMBRANE PROTEIN, OMPA-RELATED	PEPTIDOGLYCAN-ASSOCIATED LIPOPROTEIN			cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;cell outer membrane#GO:0009279;membrane#GO:0016020;external encapsulating structure#GO:0030312;outer membrane#GO:0019867;extracellular region#GO:0005576		
ECOLI|EnsemblGenome=b2774|UniProtKB=P76633	P76633	ygcW	PTHR42760:SF5	SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER	2-DEHYDRO-3-DEOXY-D-GLUCONATE 5-DEHYDROGENASE	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1208|UniProtKB=P62615	P62615	ispE	PTHR43527:SF2	4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE, CHLOROPLASTIC	4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE, CHLOROPLASTIC	kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773			metabolite interconversion enzyme#PC00262;kinase#PC00137;amino acid kinase#PC00045	
ECOLI|EnsemblGenome=b1785|UniProtKB=P76236	P76236	cdgI	PTHR45138:SF31	REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM	DIGUANYLATE CYCLASE DGCM-RELATED	nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772	negative regulation of cellular process#GO:0048523;single-species biofilm formation#GO:0044010;cell adhesion#GO:0007155;regulation of cell motility#GO:2000145;cell-substrate adhesion#GO:0031589;negative regulation of biological process#GO:0048519;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of locomotion#GO:0040012;negative regulation of cell motility#GO:2000146;biological regulation#GO:0065007;negative regulation of locomotion#GO:0040013	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b1082|UniProtKB=P33235	P33235	flgK	PTHR30033:SF1	FLAGELLAR HOOK-ASSOCIATED PROTEIN 1	FLAGELLAR HOOK-ASSOCIATED PROTEIN 1		cellular component assembly#GO:0022607;cell projection organization#GO:0030030;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;bacterial-type flagellum assembly#GO:0044780;organelle assembly#GO:0070925		structural protein#PC00211	
ECOLI|EnsemblGenome=b0833|UniProtKB=P75800	P75800	pdeI	PTHR33121:SF71	CYCLIC DI-GMP PHOSPHODIESTERASE PDEF	CYCLIC DI-GMP PHOSPHODIESTERASE PDEL-RELATED	hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121	
ECOLI|EnsemblGenome=b1526|UniProtKB=P77309	P77309	yneJ	PTHR30126:SF40	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR NMOR	binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468		helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b3482|UniProtKB=P16917	P16917	rhsB	PTHR32305:SF18	FAMILY NOT NAMED	PROTEIN RHSA-RELATED					
ECOLI|EnsemblGenome=b0046|UniProtKB=P0A754	P0A754	kefF	PTHR47307:SF2	GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYSTEM ANCILLARY PROTEIN KEFG	GLUTATHIONE-REGULATED POTASSIUM-EFFLUX SYSTEM ANCILLARY PROTEIN KEFF	oxidoreductase activity, acting on NAD(P)H#GO:0016651;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;NAD(P)H dehydrogenase (quinone) activity#GO:0003955;nucleotide binding#GO:0000166;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;carbohydrate derivative binding#GO:0097367;catalytic activity#GO:0003824;ribonucleotide binding#GO:0032553				
ECOLI|EnsemblGenome=b3304|UniProtKB=P0C018	P0C018	rplR	PTHR12899:SF22	39S RIBOSOMAL PROTEIN L18, MITOCHONDRIAL	LARGE RIBOSOMAL SUBUNIT PROTEIN UL18	rRNA binding#GO:0019843;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723		membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840	translational protein#PC00263;ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b2124|UniProtKB=P33355	P33355	yehS	PTHR37805:SF1	CYTOPLASMIC PROTEIN-RELATED	DUF1456 DOMAIN-CONTAINING PROTEIN					
ECOLI|EnsemblGenome=b4230|UniProtKB=P39328	P39328	ytfT	PTHR32196:SF19	ABC TRANSPORTER PERMEASE PROTEIN YPHD-RELATED-RELATED	GALACTOFURANOSE TRANSPORTER PERMEASE PROTEIN YTFT			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0158|UniProtKB=P37028	P37028	btuF	PTHR42860:SF4	VITAMIN B12-BINDING PROTEIN	VITAMIN B12-BINDING PROTEIN		nitrogen compound transport#GO:0071705;transport#GO:0006810;establishment of localization#GO:0051234;vitamin transport#GO:0051180;localization#GO:0051179	transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;ATPase dependent transmembrane transport complex#GO:0098533;membrane protein complex#GO:0098796;membrane#GO:0016020;ATP-binding cassette (ABC) transporter complex#GO:0043190;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b0421|UniProtKB=P22939	P22939	ispA	PTHR43281:SF36	FARNESYL DIPHOSPHATE SYNTHASE	FARNESYL DIPHOSPHATE SYNTHASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659	primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987;terpenoid metabolic process#GO:0006721;isoprenoid metabolic process#GO:0006720		acyltransferase#PC00042;transferase#PC00220	
ECOLI|EnsemblGenome=b3943|UniProtKB=P0ABT8	P0ABT8	yijE	PTHR22911:SF132	ACYL-MALONYL CONDENSING ENZYME-RELATED	CYSTINE TRANSPORTER YIJE-RELATED			cellular anatomical structure#GO:0110165;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b1717|UniProtKB=P0A7Q1	P0A7Q1	rpmI	PTHR33343:SF1	54S RIBOSOMAL PROTEIN BL35M	LARGE RIBOSOMAL SUBUNIT PROTEIN BL35M	structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735	metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229	ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b1554|UniProtKB=P76159	P76159	rrrQ	PTHR38107:SF3	FAMILY NOT NAMED	LYSOZYME RRRD-RELATED					
ECOLI|EnsemblGenome=b0393|UniProtKB=P36767	P36767	rdgC	PTHR38103:SF1	RECOMBINATION-ASSOCIATED PROTEIN RDGC	RECOMBINATION-ASSOCIATED PROTEIN RDGC					
ECOLI|EnsemblGenome=b1752|UniProtKB=P76221	P76221	ydjZ	PTHR12677:SF60	GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED	TVP38_TMEM64 FAMILY INNER MEMBRANE PROTEIN YDJZ			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1802|UniProtKB=P0ABR7	P0ABR7	yeaW	PTHR43756:SF5	CHOLINE MONOOXYGENASE, CHLOROPLASTIC	CHOLINE MONOOXYGENASE, CHLOROPLASTIC				oxidoreductase#PC00176;oxygenase#PC00177	
ECOLI|EnsemblGenome=b0784|UniProtKB=P30748	P30748	moaD	PTHR33359:SF1	MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT	MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT		metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;biosynthetic process#GO:0009058	transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737	transfer/carrier protein#PC00219	
ECOLI|EnsemblGenome=b3550|UniProtKB=P37664	P37664	yiaC	PTHR43420:SF51	ACETYLTRANSFERASE	PEPTIDYL-LYSINE N-ACETYLTRANSFERASE YIAC	protein N-acyltransferase activity#GO:0140186;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;N-acetyltransferase activity#GO:0008080;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740			acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b4129|UniProtKB=P0A8N5	P0A8N5	lysU	PTHR42918:SF17	LYSYL-TRNA SYNTHETASE	LYSINE--TRNA LIGASE-RELATED	catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049	cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263	
ECOLI|EnsemblGenome=b1799|UniProtKB=P76250	P76250	dmlR	PTHR30537:SF5	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL ACTIVATOR TTDR-RELATED	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794		helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b2868|UniProtKB=Q46801	Q46801	xdhC	PTHR44379:SF8	OXIDOREDUCTASE WITH IRON-SULFUR SUBUNIT	XANTHINE DEHYDROGENASE IRON-SULFUR-BINDING SUBUNIT XDHC-RELATED				oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2372|UniProtKB=P0AA49	P0AA49	yfdV	PTHR36838:SF1	AUXIN EFFLUX CARRIER FAMILY PROTEIN	AUXIN EFFLUX CARRIER			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b3805|UniProtKB=P06983	P06983	hemC	PTHR11557:SF0	PORPHOBILINOGEN DEAMINASE	PORPHOBILINOGEN DEAMINASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765	porphyrin-containing compound biosynthetic process#GO:0006779;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;heme biosynthetic process#GO:0006783;pigment metabolic process#GO:0042440;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	metabolite interconversion enzyme#PC00262;deaminase#PC00088	Heme biosynthesis#P02746>Hydroxymethylbilane synthase#P02983
ECOLI|EnsemblGenome=b0041|UniProtKB=P60566	P60566	fixA	PTHR21294:SF22	ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT	PROTEIN FIXA-RELATED				metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0632|UniProtKB=P0AEB2	P0AEB2	dacA	PTHR21581:SF27	D-ALANYL-D-ALANINE CARBOXYPEPTIDASE	D-ALANYL-D-ALANINE CARBOXYPEPTIDASE DACA				protease#PC00190;serine protease#PC00203	
ECOLI|EnsemblGenome=b0427|UniProtKB=P77726	P77726	yajR	PTHR23510:SF81	INNER MEMBRANE TRANSPORT PROTEIN YAJR	MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN					
ECOLI|EnsemblGenome=b2024|UniProtKB=P10371	P10371	hisA	PTHR43090:SF8	1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE	1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO)METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE	intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860	proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;aromatic amino acid biosynthetic process#GO:0009073;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	isomerase#PC00135;metabolite interconversion enzyme#PC00262	Histidine biosynthesis#P02747>Phosphoribosylformimino-5-amino-1-phosphoribosyl-4 imadazol carboxamide isomerase#P02993
ECOLI|EnsemblGenome=b4295|UniProtKB=P39356	P39356	yjhU	PTHR34294:SF1	TRANSCRIPTIONAL REGULATOR-RELATED	TRANSCRIPTIONAL REGULATOR LSRR	double-stranded DNA binding#GO:0003690;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription initiation#GO:2000142;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222		DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b1718|UniProtKB=P0A707	P0A707	infC	PTHR10938:SF0	TRANSLATION INITIATION FACTOR IF-3	TRANSLATION INITIATION FACTOR IF-3	translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051	metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058		translation initiation factor#PC00224	
ECOLI|EnsemblGenome=b0752|UniProtKB=P75757	P75757	zitB	PTHR11562:SF17	CATION EFFLUX PROTEIN/ ZINC TRANSPORTER	LD05335P	metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385	transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b3187|UniProtKB=P0AD57	P0AD57	ispB	PTHR12001:SF69	GERANYLGERANYL PYROPHOSPHATE SYNTHASE	OCTAPRENYL DIPHOSPHATE SYNTHASE	transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;catalytic activity#GO:0003824	lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;metabolic process#GO:0008152;isoprenoid biosynthetic process#GO:0008299;lipid metabolic process#GO:0006629		metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0108|UniProtKB=P36647	P36647	ppdD	PTHR30093:SF34	GENERAL SECRETION PATHWAY PROTEIN G	PREPILIN PEPTIDASE-DEPENDENT PROTEIN D		cell motility#GO:0048870;type IV pilus-dependent motility#GO:0043107;cellular process#GO:0009987	cell projection#GO:0042995;cellular anatomical structure#GO:0110165;type IV pilus#GO:0044096		
ECOLI|EnsemblGenome=b1976|UniProtKB=P76346	P76346	mtfA	PTHR30164:SF2	MTFA PEPTIDASE	MLC TITRATION FACTOR A	hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	protein modifying enzyme#PC00260;metalloprotease#PC00153	
ECOLI|EnsemblGenome=b1096|UniProtKB=P28305	P28305	pabC	PTHR42743:SF2	AMINO-ACID AMINOTRANSFERASE	AMINODEOXYCHORISMATE LYASE	carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;lyase activity#GO:0016829	monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;aromatic amino acid biosynthetic process#GO:0009073;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1869|UniProtKB=P64515	P64515	yecN	PTHR35814:SF1	FAMILY NOT NAMED	GLUTATHIONE S-TRANSFERASE			cellular anatomical structure#GO:0110165;membrane#GO:0016020		
ECOLI|EnsemblGenome=b1451|UniProtKB=P76115	P76115	pqqU	PTHR30069:SF28	TONB-DEPENDENT OUTER MEMBRANE RECEPTOR	PYRROLOQUINOLINE QUINONE TRANSPORTER	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;siderophore-iron transmembrane transporter activity#GO:0015343	metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;transition metal ion transport#GO:0000041;transport#GO:0006810;iron ion transport#GO:0006826;iron coordination entity transport#GO:1901678	external encapsulating structure#GO:0030312;cell outer membrane#GO:0009279;membrane#GO:0016020;extracellular region#GO:0005576;outer membrane#GO:0019867;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313		
ECOLI|EnsemblGenome=b1710|UniProtKB=P06610	P06610	btuE	PTHR11592:SF40	GLUTATHIONE PEROXIDASE	THIOREDOXIN_GLUTATHIONE PEROXIDASE BTUE	antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684	cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197		oxidoreductase#PC00176;peroxidase#PC00180	
ECOLI|EnsemblGenome=b0990|UniProtKB=P0A978	P0A978	cspG	PTHR11544:SF138	COLD SHOCK DOMAIN CONTAINING PROTEINS	COLD SHOCK PROTEIN CSPA-RELATED					
ECOLI|EnsemblGenome=b1492|UniProtKB=P63235	P63235	gadC	PTHR42770:SF15	AMINO ACID TRANSPORTER-RELATED	GLUTAMATE_GAMMA-AMINOBUTYRATE ANTIPORTER-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	secondary carrier transporter#PC00258;amino acid transporter#PC00046;transporter#PC00227	
ECOLI|Gene_OrderedLocusName=JW5024|UniProtKB=P75679	P75679	insN1	PTHR33215:SF12	PROTEIN DISTAL ANTENNA	TRANSPOSASE INSN FOR INSERTION SEQUENCE ELEMENT IS911A-RELATED					
ECOLI|EnsemblGenome=b3288|UniProtKB=P23882	P23882	fmt	PTHR11138:SF6	METHIONYL-TRNA FORMYLTRANSFERASE	METHIONYL-TRNA FORMYLTRANSFERASE	catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741	nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170		RNA processing factor#PC00147;RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b4059|UniProtKB=P0AGE0	P0AGE0	ssb	PTHR10302:SF27	SINGLE-STRANDED DNA-BINDING PROTEIN	SINGLE-STRANDED DNA-BINDING PROTEIN	single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488;molecular function activator activity#GO:0140677;DNA binding#GO:0003677;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772	cellular process#GO:0009987;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170	nucleoid#GO:0009295;cellular anatomical structure#GO:0110165	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b0897|UniProtKB=P21367	P21367	ycaC	PTHR43559:SF3	HYDROLASE YCAC-RELATED	HYDROLASE YCAC-RELATED				hydrolase#PC00121;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1840|UniProtKB=P76278	P76278	yebZ	PTHR34820:SF4	INNER MEMBRANE PROTEIN YEBZ	COPPER TRANSPORTER YEBZ			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2549|UniProtKB=P76585	P76585	yphG	PTHR12558:SF52	CELL DIVISION CYCLE 16,23,27	LIPOPROTEIN NLPI				ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260	
ECOLI|EnsemblGenome=b0111|UniProtKB=P0AE14	P0AE14	ampE	PTHR38684:SF1	PROTEIN AMPE	PROTEIN AMPE		response to stimulus#GO:0050896;response to chemical#GO:0042221;response to antibiotic#GO:0046677	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b0623|UniProtKB=P0A972	P0A972	cspE	PTHR11544:SF138	COLD SHOCK DOMAIN CONTAINING PROTEINS	COLD SHOCK PROTEIN CSPA-RELATED					
ECOLI|EnsemblGenome=b3891|UniProtKB=P13024	P13024	fdhE	PTHR37689:SF1	PROTEIN FDHE	PROTEIN FDHE	transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;iron ion binding#GO:0005506	macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2499|UniProtKB=P08178	P08178	purM	PTHR10520:SF12	TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3-RELATED	TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3	ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824	nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;purine nucleobase metabolic process#GO:0006144;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		De novo purine biosynthesis#P02738>Phosphoribosylamine glycine ligase#P02908
ECOLI|EnsemblGenome=b1601|UniProtKB=P0AFS5	P0AFS5	tqsA	PTHR21716:SF64	TRANSMEMBRANE PROTEIN	AI-2 TRANSPORT PROTEIN TQSA		cell communication#GO:0007154;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organic hydroxy compound transport#GO:0015850;transport#GO:0006810;response to stimulus#GO:0050896;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;response to biotic stimulus#GO:0009607;detection of stimulus#GO:0051606;regulation of biological process#GO:0050789;cellular process#GO:0009987	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b4210|UniProtKB=P39314	P39314	ytfF	PTHR42920:SF11	OS03G0707200 PROTEIN-RELATED	INNER MEMBRANE PROTEIN YTFF			membrane#GO:0016020;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b3506|UniProtKB=P37194	P37194	slp	PTHR37530:SF1	OUTER MEMBRANE PROTEIN SLP	OUTER MEMBRANE PROTEIN SLP			cellular anatomical structure#GO:0110165;outer membrane#GO:0019867;membrane#GO:0016020		
ECOLI|EnsemblGenome=b3972|UniProtKB=P08373	P08373	murB	PTHR21071:SF4	UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINE REDUCTASE	UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINE REDUCTASE	catalytic activity#GO:0003824;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627	cellular component organization#GO:0016043;cellular process#GO:0009987;cell wall organization#GO:0071555;cell wall organization or biogenesis#GO:0071554;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;reductase#PC00198	Peptidoglycan biosynthesis#P02763>UDP-N-acetylmuramate dehydrogenase#P03088
ECOLI|EnsemblGenome=b0323|UniProtKB=P77624	P77624	yahI	PTHR30409:SF1	CARBAMATE KINASE	CARBAMATE KINASE-LIKE PROTEIN YAHI-RELATED	kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	kinase#PC00137;transferase#PC00220	
ECOLI|EnsemblGenome=b0472|UniProtKB=P0A7H6	P0A7H6	recR	PTHR30446:SF0	RECOMBINATION PROTEIN RECR	RECOMBINATION PROTEIN RECR		response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310			
ECOLI|EnsemblGenome=b0693|UniProtKB=P24169	P24169	speF	PTHR45229:SF1	CONSTITUTIVE ORNITHINE DECARBOXYLASE	INDUCIBLE ORNITHINE DECARBOXYLASE	lyase activity#GO:0016829;ornithine decarboxylase activity#GO:0004586;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;heterocyclic compound binding#GO:1901363;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;lyase#PC00144;decarboxylase#PC00089	
ECOLI|EnsemblGenome=b1403|UniProtKB=P0CF41	P0CF41	insC2	PTHR37936:SF3	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b3780|UniProtKB=P0A8J8	P0A8J8	rhlB	PTHR47959:SF10	ATP-DEPENDENT RNA HELICASE RHLE-RELATED	ATP-DEPENDENT RNA HELICASE RHLB	ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	RNA helicase#PC00032	
ECOLI|EnsemblGenome=b3747|UniProtKB=P63183	P63183	kup	PTHR30540:SF79	OSMOTIC STRESS POTASSIUM TRANSPORTER	LOW AFFINITY POTASSIUM TRANSPORT SYSTEM PROTEIN KUP				transporter#PC00227	
ECOLI|EnsemblGenome=b3956|UniProtKB=P00864	P00864	ppc	PTHR30523:SF6	PHOSPHOENOLPYRUVATE CARBOXYLASE	PHOSPHOENOLPYRUVATE CARBOXYLASE	catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829	glucose metabolic process#GO:0006006;small molecule biosynthetic process#GO:0044283;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;cellular process#GO:0009987;gluconeogenesis#GO:0006094;oxoacid metabolic process#GO:0043436;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;hexose biosynthetic process#GO:0019319;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;lyase#PC00144	
ECOLI|EnsemblGenome=b3492|UniProtKB=P37631	P37631	rdsA	PTHR42887:SF3	OS12G0638800 PROTEIN	RIBOSOMAL RNA DIHYDROURIDINE SYNTHASE	catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491	gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA modification#GO:0000154;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0917|UniProtKB=P0AAZ7	P0AAZ7	ycaR	PTHR33505:SF8	ZGC:162634	METHYLTRANSFERASE ACTIVATOR TRM112 HOMOLOG			cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		
ECOLI|EnsemblGenome=b3146|UniProtKB=P67087	P67087	rsmI	PTHR46111:SF3	RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I	RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I	transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;O-methyltransferase activity#GO:0008171;catalytic activity, acting on a rRNA#GO:0140102	rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774		RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b1000|UniProtKB=P36659	P36659	cbpA	PTHR43096:SF52	DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED	DNAJ HOMOLOG 1, MITOCHONDRIAL		primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein refolding#GO:0042026	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	chaperone#PC00072	
ECOLI|EnsemblGenome=b0595|UniProtKB=P0ADI4	P0ADI4	entB	PTHR43540:SF3	PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED	ENTEROBACTIN SYNTHASE COMPONENT B			intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	hydrolase#PC00121	
ECOLI|EnsemblGenome=b2959|UniProtKB=P38521	P38521	yggL	PTHR38778:SF1	CYTOPLASMIC PROTEIN-RELATED	RIBOSOME ASSEMBLY FACTOR YGGL			cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		
ECOLI|EnsemblGenome=b1628|UniProtKB=P77223	P77223	rsxB	PTHR42859:SF3	OXIDOREDUCTASE	ION-TRANSLOCATING OXIDOREDUCTASE COMPLEX SUBUNIT B				oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b4298|UniProtKB=P39359	P39359	yjhH	PTHR12128:SF28	DIHYDRODIPICOLINATE SYNTHASE	2-DEHYDRO-3-DEOXY-D-GLUCONATE ALDOLASE YAGE-RELATED	lyase activity#GO:0016829;catalytic activity#GO:0003824		cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	lyase#PC00144	Lysine biosynthesis#P02751>Dihydrodipicolinate synthase#P03008
ECOLI|EnsemblGenome=b4070|UniProtKB=P0ABK9	P0ABK9	nrfA	PTHR30633:SF0	CYTOCHROME C-552 RESPIRATORY NITRITE REDUCTASE	CYTOCHROME C-552	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;anaerobic respiration#GO:0009061;anaerobic electron transport chain#GO:0019645;electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904	periplasmic space#GO:0042597;extracellular region#GO:0005576;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313	metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0822|UniProtKB=P75792	P75792	ybiV	PTHR10000:SF53	PHOSPHOSERINE PHOSPHATASE	5-AMINO-6-(5-PHOSPHO-D-RIBITYLAMINO)URACIL PHOSPHATASE YBJI-RELATED	small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;magnesium ion binding#GO:0000287;cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578		cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	protein phosphatase#PC00195	
ECOLI|EnsemblGenome=b1304|UniProtKB=P0AFM6	P0AFM6	pspA	PTHR31088:SF15	MEMBRANE-ASSOCIATED PROTEIN VIPP1, CHLOROPLASTIC	PHAGE SHOCK PROTEIN A		response to stress#GO:0006950;response to stimulus#GO:0050896	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2409|UniProtKB=P0ACR7	P0ACR7	yfeR	PTHR30419:SF14	HTH-TYPE TRANSCRIPTIONAL REGULATOR YBHD	POSSIBLE TRANSCRIPTIONAL REGULATOR	nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677	biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b2807|UniProtKB=P0ADR2	P0ADR2	ygdD	PTHR43461:SF2	TRANSMEMBRANE PROTEIN 256	UPF0382 INNER MEMBRANE PROTEIN YGDD			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b4300|UniProtKB=P39361	P39361	sgcR	PTHR30363:SF24	HTH-TYPE TRANSCRIPTIONAL REGULATOR SRLR-RELATED	SGC REGION TRANSCRIPTIONAL REGULATOR-RELATED	nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355		DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b1780|UniProtKB=P39173	P39173	yeaD	PTHR11122:SF61	APOSPORY-ASSOCIATED PROTEIN C-RELATED	GLUCOSE-6-PHOSPHATE 1-EPIMERASE-RELATED					
ECOLI|EnsemblGenome=b2026|UniProtKB=P06989	P06989	hisI	PTHR42945:SF9	HISTIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN	HISTIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN HISIE	catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814	proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;aromatic amino acid biosynthetic process#GO:0009073		metabolite interconversion enzyme#PC00262;hydrolase#PC00121	Histidine biosynthesis#P02747>Phosphoribosyl AMP cyclohydrolase#P02989;Histidine biosynthesis#P02747>Phosphoribosyl ATP pyrophosphatase#P02986
ECOLI|EnsemblGenome=b2167|UniProtKB=P20966	P20966	fruA	PTHR30505:SF32	FRUCTOSE-LIKE PERMEASE	PTS SYSTEM FRUCTOSE-SPECIFIC EIIB'BC COMPONENT	protein-phosphocysteine-sugar phosphotransferase activity#GO:0090563;phosphotransferase activity, alcohol group as acceptor#GO:0016773;carbohydrate transmembrane transporter activity#GO:0015144;catalytic activity#GO:0003824;transferase activity#GO:0016740;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transferase activity, transferring phosphorus-containing groups#GO:0016772;active transmembrane transporter activity#GO:0022804	carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739;cellular process#GO:0009987;import into cell#GO:0098657;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;transport#GO:0006810;carbohydrate transport#GO:0008643	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b3611|UniProtKB=P0AG27	P0AG27	yibN	PTHR43031:SF18	FAD-DEPENDENT OXIDOREDUCTASE	RHODANESE-RELATED SULFURTRANSFERASES	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2570|UniProtKB=P46187	P46187	rseC	PTHR35867:SF1	PROTEIN RSEC	PROTEIN RSEC			catalytic complex#GO:1902494;cell periphery#GO:0071944;membrane#GO:0016020;oxidoreductase complex#GO:1990204;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991		
ECOLI|EnsemblGenome=b0369|UniProtKB=P0ACB2	P0ACB2	hemB	PTHR11458:SF1	DELTA-AMINOLEVULINIC ACID DEHYDRATASE	DELTA-AMINOLEVULINIC ACID DEHYDRATASE	carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824	tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;cellular process#GO:0009987;porphyrin-containing compound biosynthetic process#GO:0006779;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	dehydratase#PC00091	Heme biosynthesis#P02746>porphobilinogen synthase#P02979
ECOLI|EnsemblGenome=b0890|UniProtKB=P46889	P46889	ftsK	PTHR22683:SF41	SPORULATION PROTEIN RELATED	DNA TRANSLOCASE FTSK				DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b2574|UniProtKB=P10902	P10902	nadB	PTHR42716:SF2	L-ASPARTATE OXIDASE	L-ASPARTATE OXIDASE	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;oxoacid metabolic process#GO:0043436;pyridine-containing compound metabolic process#GO:0072524;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086		oxidase#PC00175	
ECOLI|EnsemblGenome=b4267|UniProtKB=P39346	P39346	idnD	PTHR43189:SF1	ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C1198.01-RELATED	L-IDONATE 5-DEHYDROGENASE (NAD(P)(+))	oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824	small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;monocarboxylic acid catabolic process#GO:0072329;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carbohydrate catabolic process#GO:0016052;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152		dehydrogenase#PC00092;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0768|UniProtKB=P52696	P52696	ybhD	PTHR30419:SF30	HTH-TYPE TRANSCRIPTIONAL REGULATOR YBHD	DHCR, TRANSCRIPTIONAL REGULATOR	sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676	regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b3437|UniProtKB=P46859	P46859	gntK	PTHR43442:SF1	GLUCONOKINASE-RELATED	THERMORESISTANT GLUCONOKINASE	kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773	cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;pentose-phosphate shunt#GO:0006098;oxoacid metabolic process#GO:0043436;nucleotide metabolic process#GO:0009117		kinase#PC00137	
ECOLI|EnsemblGenome=b4237|UniProtKB=P0A9N8	P0A9N8	nrdG	PTHR30352:SF2	PYRUVATE FORMATE-LYASE-ACTIVATING ENZYME	ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE-ACTIVATING PROTEIN	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound metabolic process#GO:0006139	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;catalytic complex#GO:1902494		
ECOLI|EnsemblGenome=b2667|UniProtKB=P77295	P77295	ygaV	PTHR33154:SF28	TRANSCRIPTIONAL REGULATOR, ARSR FAMILY	HTH-TYPE TRANSCRIPTIONAL REGULATOR YGAV		regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468		winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b0513|UniProtKB=P77328	P77328	ybbY	PTHR42810:SF6	PURINE PERMEASE C1399.01C-RELATED	PURINE PERMEASE YBBY-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;nucleobase transmembrane transporter activity#GO:0015205	transport#GO:0006810;nitrogen compound transport#GO:0071705;nucleobase transport#GO:0015851;establishment of localization#GO:0051234;localization#GO:0051179	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b3230|UniProtKB=P0A7X3	P0A7X3	rpsI	PTHR21569:SF46	RIBOSOMAL PROTEIN S9	SMALL RIBOSOMAL SUBUNIT PROTEIN US9M	RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735		cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622	ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b1197|UniProtKB=P13482	P13482	treA	PTHR23403:SF1	TREHALASE	TREHALASE	hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824	catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;oligosaccharide metabolic process#GO:0009311;metabolic process#GO:0008152			
ECOLI|EnsemblGenome=b1424|UniProtKB=P40120	P40120	mdoD	PTHR30504:SF3	GLUCANS BIOSYNTHESIS PROTEIN	GLUCANS BIOSYNTHESIS PROTEIN D		polysaccharide metabolic process#GO:0005976;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975;carbohydrate biosynthetic process#GO:0016051;beta-glucan metabolic process#GO:0051273;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;beta-glucan biosynthetic process#GO:0051274;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;glucan biosynthetic process#GO:0009250;metabolic process#GO:0008152;polysaccharide biosynthetic process#GO:0000271	periplasmic space#GO:0042597;extracellular region#GO:0005576;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313		
ECOLI|EnsemblGenome=b2412|UniProtKB=P77173	P77173	zipA	PTHR38685:SF1	CELL DIVISION PROTEIN ZIPA	CELL DIVISION PROTEIN ZIPA		cellular component assembly#GO:0022607;cell septum assembly#GO:0090529;cellular component biogenesis#GO:0044085;cell cycle#GO:0007049;cellular component organization#GO:0016043;cell cycle process#GO:0022402;cellular process#GO:0009987;cell division#GO:0051301;cellular component organization or biogenesis#GO:0071840;division septum assembly#GO:0000917;cytokinesis#GO:0000910;cytokinetic process#GO:0032506	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell division site#GO:0032153		
ECOLI|EnsemblGenome=b0818|UniProtKB=P75788	P75788	ybiR	PTHR43568:SF1	P PROTEIN	CITRATE TRANSPORTER-LIKE DOMAIN-CONTAINING PROTEIN-RELATED				primary active transporter#PC00068;transporter#PC00227	
ECOLI|EnsemblGenome=b0014|UniProtKB=P0A6Y8	P0A6Y8	dnaK	PTHR19375:SF586	HEAT SHOCK PROTEIN 70KDA	CHAPERONE PROTEIN DNAK	ribonucleoside triphosphate phosphatase activity#GO:0017111;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818	protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein refolding#GO:0042026;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059		Hsp70 family chaperone#PC00027;chaperone#PC00072	Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208
ECOLI|EnsemblGenome=b0356|UniProtKB=P25437	P25437	frmA	PTHR43880:SF12	ALCOHOL DEHYDROGENASE	ALCOHOL DEHYDROGENASE CLASS-3	transition metal ion binding#GO:0046914;ion binding#GO:0043167;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;metal ion binding#GO:0046872;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;zinc ion binding#GO:0008270;catalytic activity#GO:0003824;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491	cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;cellular response to oxygen-containing compound#GO:1901701;aldehyde catabolic process#GO:0046185;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;response to chemical#GO:0042221;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;cellular detoxification of aldehyde#GO:0110095;small molecule catabolic process#GO:0044282;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b1835|UniProtKB=P76273	P76273	rsmF	PTHR22807:SF53	NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN  DOMAIN-CONTAINING	RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE F	catalytic activity, acting on a rRNA#GO:0140102;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740	nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;rRNA base methylation#GO:0070475;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;methylation#GO:0032259;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774		RNA metabolism protein#PC00031;RNA methyltransferase#PC00033	
ECOLI|EnsemblGenome=b1854|UniProtKB=P21599	P21599	pykA	PTHR11817:SF125	PYRUVATE KINASE	PYRUVATE KINASE II	phosphotransferase activity, alcohol group as acceptor#GO:0016773;pyruvate kinase activity#GO:0004743;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772	purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;ADP catabolic process#GO:0046032;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;ribonucleoside diphosphate metabolic process#GO:0009185;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	kinase#PC00137	Pyruvate metabolism#P02772>Pyruvate Kinase#P03132
ECOLI|EnsemblGenome=b0400|UniProtKB=P08400	P08400	phoR	PTHR45453:SF1	PHOSPHATE REGULON SENSOR PROTEIN PHOR	PHOSPHATE REGULON SENSOR PROTEIN PHOR	phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;phosphorelay sensor kinase activity#GO:0000155;transferase activity#GO:0016740;kinase activity#GO:0016301;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;protein histidine kinase activity#GO:0004673;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772	cellular response to starvation#GO:0009267;cellular response to stress#GO:0033554;cellular response to nutrient levels#GO:0031669;response to stimulus#GO:0050896;response to starvation#GO:0042594;response to nutrient levels#GO:0031667;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b2048|UniProtKB=P24175	P24175	manB	PTHR43771:SF1	PHOSPHOMANNOMUTASE	PHOSPHOMANNOMUTASE	intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;intramolecular phosphotransferase activity#GO:0016868;isomerase activity#GO:0016853			mutase#PC00160;isomerase#PC00135	
ECOLI|EnsemblGenome=b0937|UniProtKB=P80644	P80644	ssuE	PTHR43408:SF1	FMN REDUCTASE (NADPH)	FMN REDUCTASE (NADPH)	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	response to stress#GO:0006950;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896	cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;cytosol#GO:0005829;catalytic complex#GO:1902494	metabolite interconversion enzyme#PC00262;reductase#PC00198	
ECOLI|EnsemblGenome=b0104|UniProtKB=P60560	P60560	guaC	PTHR43170:SF6	GMP REDUCTASE	GMP REDUCTASE			cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176;reductase#PC00198	
ECOLI|EnsemblGenome=b1009|UniProtKB=P75895	P75895	rutD	PTHR43329:SF168	EPOXIDE HYDROLASE	CARBAMATE HYDROLASE RUTD-RELATED	catalytic activity#GO:0003824;hydrolase activity#GO:0016787			hydrolase#PC00121	
ECOLI|Gene_OrderedLocusName=b4580|UniProtKB=P77199	P77199	yaiT	PTHR35037:SF2	C-TERMINAL REGION OF AIDA-LIKE PROTEIN	SUBFAMILY NOT NAMED					
ECOLI|EnsemblGenome=b2567|UniProtKB=P0A7Y0	P0A7Y0	rnc	PTHR11207:SF0	RIBONUCLEASE III	RIBONUCLEASE 3	binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725;hydrolase activity#GO:0016787;RNA binding#GO:0003723;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519	nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468		RNA metabolism protein#PC00031;endoribonuclease#PC00094	
ECOLI|EnsemblGenome=b2949|UniProtKB=P0A8I1	P0A8I1	yqgF	PTHR33317:SF4	POLYNUCLEOTIDYL TRANSFERASE, RIBONUCLEASE H-LIKE SUPERFAMILY PROTEIN	POLYNUCLEOTIDYL TRANSFERASE, RIBONUCLEASE H-LIKE SUPERFAMILY PROTEIN	exonuclease activity#GO:0004527;hydrolase activity#GO:0016787;3'-5'-DNA exonuclease activity#GO:0008296;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;DNA exonuclease activity#GO:0004529;catalytic activity, acting on DNA#GO:0140097;3'-5' exonuclease activity#GO:0008408	cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304		RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b1757|UniProtKB=P78067	P78067	ynjE	PTHR11364:SF41	THIOSULFATE SULFERTANSFERASE	THIOSULFATE SULFURTRANSFERASE YNJE	transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783;catalytic activity#GO:0003824;transferase activity#GO:0016740			transferase#PC00220	
ECOLI|EnsemblGenome=b1700|UniProtKB=P77714	P77714	ydiT	PTHR43082:SF3	FERREDOXIN-LIKE	FERREDOXIN-LIKE PROTEIN YDIT				metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2015|UniProtKB=P76369	P76369	yeeY	PTHR30126:SF4	HTH-TYPE TRANSCRIPTIONAL REGULATOR	TRANSCRIPTIONAL REGULATOR	double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252		gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b0311|UniProtKB=P17444	P17444	betA	PTHR11552:SF232	GLUCOSE-METHANOL-CHOLINE  GMC  OXIDOREDUCTASE	OXYGEN-DEPENDENT CHOLINE DEHYDROGENASE	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824			metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b2292|UniProtKB=P0AFU2	P0AFU2	yfbS	PTHR43652:SF1	BASIC AMINO ACID ANTIPORTER YFCC-RELATED	CATION TRANSPORTER			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227;primary active transporter#PC00068	
ECOLI|Gene_OrderedLocusName=JW2655|UniProtKB=P76628	P76628	ygaY	PTHR42910:SF1	TRANSPORTER SCO4007-RELATED	MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN				transporter#PC00227	
ECOLI|EnsemblGenome=b4168|UniProtKB=P0AF67	P0AF67	tsaE	PTHR33540:SF2	TRNA THREONYLCARBAMOYLADENOSINE BIOSYNTHESIS PROTEIN TSAE	TRNA THREONYLCARBAMOYLADENOSINE BIOSYNTHESIS PROTEIN TSAE		metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400		RNA processing factor#PC00147;RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b3414|UniProtKB=P63020	P63020	nfuA	PTHR11178:SF51	IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED	FE_S BIOGENESIS PROTEIN NFUA					
ECOLI|EnsemblGenome=b3282|UniProtKB=P45748	P45748	tsaC	PTHR17490:SF18	SUA5	THREONYLCARBAMOYL-AMP SYNTHASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;tRNA binding#GO:0000049	RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b0759|UniProtKB=P09147	P09147	galE	PTHR43725:SF57	UDP-GLUCOSE 4-EPIMERASE	UDP-GLUCOSE 4-EPIMERASE	catalytic activity#GO:0003824;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;racemase and epimerase activity#GO:0016854;isomerase activity#GO:0016853	small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;primary metabolic process#GO:0044238;monosaccharide metabolic process#GO:0005996;cellular process#GO:0009987	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	epimerase/racemase#PC00096	Fructose galactose metabolism#P02744>UDP Glucose 4 epimerase#P02965
ECOLI|EnsemblGenome=b4324|UniProtKB=P39161	P39161	uxuR	PTHR43537:SF55	TRANSCRIPTIONAL REGULATOR, GNTR FAMILY	UXU OPERON TRANSCRIPTIONAL REGULATOR	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976	regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889		helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b3001|UniProtKB=Q46851	Q46851	gpr	PTHR43150:SF4	HYPERKINETIC, ISOFORM M	L-GLYCERALDEHYDE 3-PHOSPHATE REDUCTASE		cellular detoxification of aldehyde#GO:0110095;ketone metabolic process#GO:0042180;cellular response to stimulus#GO:0051716;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;small molecule catabolic process#GO:0044282;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;cellular response to oxygen-containing compound#GO:1901701;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;response to chemical#GO:0042221;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;aldehyde catabolic process#GO:0046185;metabolic process#GO:0008152			
ECOLI|EnsemblGenome=b3961|UniProtKB=P0ACQ4	P0ACQ4	oxyR	PTHR30346:SF26	TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED	DNA-BINDING TRANSCRIPTIONAL DUAL REGULATOR OXYR	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789	protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993	winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b0247|UniProtKB=Q47685	Q47685	ykfG	PTHR30471:SF3	DNA REPAIR PROTEIN RADC	UPF0758 PROTEIN YEES-RELATED				DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b0107|UniProtKB=P36645	P36645	hofB	PTHR30258:SF1	TYPE II SECRETION SYSTEM PROTEIN GSPE-RELATED	PROTEIN TRANSPORT PROTEIN HOFB HOMOLOG	ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b1519|UniProtKB=P76145	P76145	tam	PTHR43861:SF8	TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED	TRANS-ACONITATE 2-METHYLTRANSFERASE	S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;catalytic activity#GO:0003824;transferase activity#GO:0016740		intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	methyltransferase#PC00155	
ECOLI|EnsemblGenome=b1978|UniProtKB=P76347	P76347	yeeJ	PTHR39576:SF2	ATTACHING AND EFFACING PROTEIN HOMOLOG-RELATED-RELATED	INVERSE AUTOTRANSPORTER ADHESIN YEEJ-RELATED			membrane#GO:0016020;cell outer membrane#GO:0009279;external encapsulating structure#GO:0030312;outer membrane#GO:0019867;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313		
ECOLI|EnsemblGenome=b3018|UniProtKB=P26647	P26647	plsC	PTHR10434:SF68	1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE	1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE	acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747	metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058	endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886	acyltransferase#PC00042;transferase#PC00220	
ECOLI|EnsemblGenome=b4299|UniProtKB=P39360	P39360	yjhI	PTHR30136:SF7	HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY	HTH-TYPE TRANSCRIPTIONAL REGULATOR KDGR-RELATED	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789		winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b1522|UniProtKB=P76147	P76147	dgcF	PTHR45138:SF31	REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM	DIGUANYLATE CYCLASE DGCM-RELATED	nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772	regulation of cell motility#GO:2000145;cell-substrate adhesion#GO:0031589;single-species biofilm formation#GO:0044010;negative regulation of cellular process#GO:0048523;cell adhesion#GO:0007155;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of cell motility#GO:2000146;negative regulation of locomotion#GO:0040013;regulation of locomotion#GO:0040012;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b2554|UniProtKB=P0AFU4	P0AFU4	glrR	PTHR32071:SF116	TRANSCRIPTIONAL REGULATORY PROTEIN	TRANSCRIPTIONAL REGULATORY PROTEIN GLRR	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;double-stranded DNA binding#GO:0003690	regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468	protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991	DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b1002|UniProtKB=P19926	P19926	agp	PTHR11567:SF135	ACID PHOSPHATASE-RELATED	GLUCOSE-1-PHOSPHATASE	catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787		periplasmic space#GO:0042597;extracellular region#GO:0005576;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313	phosphatase#PC00181	
ECOLI|EnsemblGenome=b1429|UniProtKB=P25396	P25396	tehA	PTHR37955:SF1	TELLURITE RESISTANCE PROTEIN TEHA	DEP DOMAIN-CONTAINING PROTEIN	efflux transmembrane transporter activity#GO:0015562;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b0863|UniProtKB=P30859	P30859	artI	PTHR35936:SF20	MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE F	ABC TRANSPORTER ARGININE-BINDING PROTEIN 2-RELATED	amino acid binding#GO:0016597;binding#GO:0005488		cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;extracellular region#GO:0005576;periplasmic space#GO:0042597		
ECOLI|EnsemblGenome=b2102|UniProtKB=P76421	P76421	yegX	PTHR34135:SF2	LYSOZYME	LYSOZYME		cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056			
ECOLI|EnsemblGenome=b4222|UniProtKB=P0AE48	P0AE48	ytfP	PTHR12510:SF4	TROPONIN C-AKIN-1 PROTEIN	GAMMA-GLUTAMYLAMINECYCLOTRANSFERASE			cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		
ECOLI|EnsemblGenome=b1034|UniProtKB=P75914	P75914	ycdX	PTHR36928:SF2	PHOSPHATASE YCDX-RELATED	PHOSPHATASE YCDX-RELATED	transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;hydrolase activity, acting on ester bonds#GO:0016788;zinc ion binding#GO:0008270;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578	cilium or flagellum-dependent cell motility#GO:0001539;cellular process#GO:0009987;archaeal or bacterial-type flagellum-dependent cell motility#GO:0097588;bacterial-type flagellum-dependent swarming motility#GO:0071978;bacterial-type flagellum-dependent cell motility#GO:0071973;cell motility#GO:0048870	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	phosphatase#PC00181	
ECOLI|EnsemblGenome=b3844|UniProtKB=P0AEN1	P0AEN1	fre	PTHR43644:SF1	NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT	NAD(P)H-FLAVIN REDUCTASE	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			secondary carrier transporter#PC00258;transporter#PC00227	
ECOLI|EnsemblGenome=b0712|UniProtKB=P75745	P75745	pxpC	PTHR43309:SF6	5-OXOPROLINASE SUBUNIT C	5-OXOPROLINASE SUBUNIT C			cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b2505|UniProtKB=P65290	P65290	yfgH	PTHR35603:SF1	FAMILY NOT NAMED	OUTER MEMBRANE LIPOPROTEIN SLYB			extracellular region#GO:0005576;outer membrane#GO:0019867;membrane#GO:0016020;cell outer membrane#GO:0009279;external encapsulating structure#GO:0030312;cell envelope#GO:0030313;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2269|UniProtKB=Q47013	Q47013	elaD	PTHR12606:SF141	SENTRIN/SUMO-SPECIFIC PROTEASE	GH15225P-RELATED	cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096	macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987	intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622	protease#PC00190	
ECOLI|EnsemblGenome=b0644|UniProtKB=P77234	P77234	ybeQ	PTHR43628:SF1	ACTIVATOR OF C KINASE PROTEIN 1-RELATED	B BOX-TYPE DOMAIN-CONTAINING PROTEIN-RELATED					
ECOLI|EnsemblGenome=b1642|UniProtKB=P0A8W2	P0A8W2	slyA	PTHR33164:SF64	TRANSCRIPTIONAL REGULATOR, MARR FAMILY	TRANSCRIPTIONAL REGULATOR SLYA		regulation of biological process#GO:0050789;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355		winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b0974|UniProtKB=P0AAM1	P0AAM1	hyaC	PTHR30485:SF0	NI/FE-HYDROGENASE 1 B-TYPE CYTOCHROME SUBUNIT	NI_FE-HYDROGENASE 1 B-TYPE CYTOCHROME SUBUNIT-RELATED	binding#GO:0005488;heme binding#GO:0020037;tetrapyrrole binding#GO:0046906		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b0601|UniProtKB=P77174	P77174	ybdM	PTHR30083:SF1	TRANSCRIPTIONAL REGULATOR-RELATED	LMO1309 PROTEIN		cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to chemical stimulus#GO:0070887;response to oxygen levels#GO:0070482;response to abiotic stimulus#GO:0009628;response to stimulus#GO:0050896;response to chemical#GO:0042221			
ECOLI|EnsemblGenome=b0590|UniProtKB=P23876	P23876	fepD	PTHR30472:SF1	FERRIC ENTEROBACTIN TRANSPORT SYSTEM PERMEASE PROTEIN	FE(3+) DICITRATE TRANSPORT SYSTEM PERMEASE PROTEIN FECC-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	cellular process#GO:0009987;establishment of localization in cell#GO:0051649;monoatomic ion homeostasis#GO:0050801;siderophore-iron import into cell#GO:0033214;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;iron coordination entity transport#GO:1901678;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;import into cell#GO:0098657;iron import into cell#GO:0033212;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;iron ion transport#GO:0006826;monoatomic ion transport#GO:0006811;cellular localization#GO:0051641;siderophore-dependent iron import pathway#GO:0180060;localization#GO:0051179;monoatomic cation transport#GO:0006812	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b3792|UniProtKB=P0AAA7	P0AAA7	wzxE	PTHR30250:SF30	PST FAMILY PREDICTED COLANIC ACID TRANSPORTER	LIPID III FLIPPASE			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b3294|UniProtKB=P0AG44	P0AG44	rplQ	PTHR14413:SF16	RIBOSOMAL PROTEIN L17	LARGE RIBOSOMAL SUBUNIT PROTEIN BL17	structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198	protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412		ribosomal protein#PC00202;translational protein#PC00263	
ECOLI|EnsemblGenome=b2264|UniProtKB=P17109	P17109	menD	PTHR42916:SF1	2-SUCCINYL-5-ENOLPYRUVYL-6-HYDROXY-3-CYCLOHEXENE-1-CARBOXYLATE SYNTHASE	2-SUCCINYL-5-ENOLPYRUVYL-6-HYDROXY-3-CYCLOHEXENE-1-CARBOXYLATE SYNTHASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;transketolase or transaldolase activity#GO:0016744	cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ketone metabolic process#GO:0042180;menaquinone biosynthetic process#GO:0009234;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152		transferase#PC00220;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1581|UniProtKB=P38104	P38104	rspA	PTHR48080:SF6	D-GALACTONATE DEHYDRATASE-RELATED	STARVATION-SENSING PROTEIN RSPA	lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824			dehydratase#PC00091	
ECOLI|EnsemblGenome=b2575|UniProtKB=P31825	P31825	yfiC	PTHR47739:SF1	TRNA1(VAL) (ADENINE(37)-N6)-METHYLTRANSFERASE	TRNA1(VAL) (ADENINE(37)-N6)-METHYLTRANSFERASE				RNA metabolism protein#PC00031;RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b1559|UniProtKB=P76161	P76161	quuQ	PTHR15852:SF54	PLASTID TRANSCRIPTIONALLY ACTIVE PROTEIN	PROTEIN SSUH2 HOMOLOG					
ECOLI|EnsemblGenome=b3296|UniProtKB=P0A7V8	P0A7V8	rpsD	PTHR11831:SF4	30S 40S RIBOSOMAL PROTEIN	SMALL RIBOSOMAL SUBUNIT PROTEIN US4M	structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of ribosome#GO:0003735;binding#GO:0005488;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676	cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;ribosomal small subunit biogenesis#GO:0042274;cellular process#GO:0009987	ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622	ribosomal protein#PC00202;translational protein#PC00263	
ECOLI|EnsemblGenome=b1635|UniProtKB=P0A9D2	P0A9D2	gstA	PTHR44051:SF8	GLUTATHIONE S-TRANSFERASE-RELATED	GLUTATHIONE S-TRANSFERASE GSTA	glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765		cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;transferase#PC00220	
ECOLI|EnsemblGenome=b2766|UniProtKB=Q46904	Q46904	ygcN	PTHR43624:SF2	ELECTRON TRANSFER FLAVOPROTEIN-QUINONE OXIDOREDUCTASE YDIS-RELATED	ELECTRON TRANSFER FLAVOPROTEIN-QUINONE OXIDOREDUCTASE YDIS-RELATED				oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0569|UniProtKB=P0AFA5	P0AFA5	nfrB	PTHR30258:SF27	TYPE II SECRETION SYSTEM PROTEIN GSPE-RELATED	BACTERIOPHAGE ADSORPTION PROTEIN B-RELATED	ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111	export from cell#GO:0140352;protein localization to extracellular region#GO:0071692;localization#GO:0051179;protein secretion#GO:0009306;transmembrane transport#GO:0055085;secretion#GO:0046903;secretion by cell#GO:0032940;protein transport#GO:0015031;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein secretion by the type II secretion system#GO:0015628;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;transport#GO:0006810;protein transmembrane transport#GO:0071806	type II protein secretion system complex#GO:0015627;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b0473|UniProtKB=P0A6Z3	P0A6Z3	htpG	PTHR11528:SF97	HEAT SHOCK PROTEIN 90 FAMILY MEMBER	ENDOPLASMIN HOMOLOG	pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657	biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152		Hsp90 family chaperone#PC00028;chaperone#PC00072	
ECOLI|EnsemblGenome=b0651|UniProtKB=P41409	P41409	rihA	PTHR12304:SF61	INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE	PYRIMIDINE-SPECIFIC RIBONUCLEOSIDE HYDROLASE RIHA-RELATED	catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798	metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;purine-containing compound catabolic process#GO:0072523;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;purine nucleoside metabolic process#GO:0042278;nucleoside catabolic process#GO:0009164;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;nucleoside metabolic process#GO:0009116;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	hydrolase#PC00121	
ECOLI|EnsemblGenome=b1464|UniProtKB=P37757	P37757	yddE	PTHR13774:SF39	PHENAZINE BIOSYNTHESIS PROTEIN	PHZF FAMILY PHENAZINE BIOSYNTHESIS PROTEIN					
ECOLI|EnsemblGenome=b0096|UniProtKB=P0A725	P0A725	lpxC	PTHR33694:SF1	UDP-3-O-ACYL-N-ACETYLGLUCOSAMINE DEACETYLASE 1, MITOCHONDRIAL-RELATED	UDP-3-O-ACYL-N-ACETYLGLUCOSAMINE DEACETYLASE	hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824	metabolic process#GO:0008152;lipid metabolic process#GO:0006629;carbohydrate derivative biosynthetic process#GO:1901137;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;liposaccharide metabolic process#GO:1903509;lipid A biosynthetic process#GO:0009245;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;phospholipid metabolic process#GO:0006644	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	deacetylase#PC00087	Peptidoglycan biosynthesis#P02763>N-Acetylglucosaminyl transferase#P03090
ECOLI|EnsemblGenome=b4032|UniProtKB=P68183	P68183	malG	PTHR32243:SF50	MALTOSE TRANSPORT SYSTEM PERMEASE-RELATED	MALTOSE_MALTODEXTRIN TRANSPORT SYSTEM PERMEASE PROTEIN MALG	transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399	establishment of localization#GO:0051234;localization#GO:0051179;macromolecule localization#GO:0033036;transport#GO:0006810;carbohydrate transport#GO:0008643	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	primary active transporter#PC00068;transporter#PC00227	
ECOLI|EnsemblGenome=b2902|UniProtKB=P52037	P52037	ygfF	PTHR43639:SF1	OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G02870)	SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0342|UniProtKB=P07464	P07464	lacA	PTHR43017:SF1	GALACTOSIDE O-ACETYLTRANSFERASE	ACETYLTRANSFERASE YJL218W-RELATED	acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;catalytic activity#GO:0003824			acetyltransferase#PC00038	
ECOLI|EnsemblGenome=b0534|UniProtKB=P38052	P38052	sfmF	PTHR33420:SF4	FIMBRIAL SUBUNIT ELFA-RELATED	FIMBRIAL-LIKE PROTEIN FIMF		cell-substrate adhesion#GO:0031589;single-species biofilm formation#GO:0044010;cellular process#GO:0009987;cell adhesion#GO:0007155	cell projection#GO:0042995;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b3731|UniProtKB=P0A6E6	P0A6E6	atpC	PTHR13822:SF27	ATP SYNTHASE DELTA/EPSILON CHAIN	ATP SYNTHASE EPSILON CHAIN	channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;proton channel activity#GO:0015252;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075	purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;organophosphate biosynthetic process#GO:0090407;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206	transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494;cation channel complex#GO:0034703;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;proton-transporting ATP synthase complex#GO:0045259;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803	ATP synthase#PC00002	
ECOLI|EnsemblGenome=b3522|UniProtKB=P37642	P37642	yhjD	PTHR30213:SF1	INNER MEMBRANE PROTEIN YHJD	INNER MEMBRANE PROTEIN YHJD			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b0226|UniProtKB=Q47150	Q47150	dinJ	PTHR38781:SF1	ANTITOXIN DINJ-RELATED	ANTITOXIN DINJ-RELATED		macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059			
ECOLI|EnsemblGenome=b1914|UniProtKB=P0AED5	P0AED5	uvrY	PTHR43214:SF3	TWO-COMPONENT RESPONSE REGULATOR	RESPONSE REGULATOR UVRY	DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468		winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b3520|UniProtKB=P37640	P37640	yhjB	PTHR45566:SF1	HTH-TYPE TRANSCRIPTIONAL REGULATOR YHJB-RELATED	HTH-TYPE TRANSCRIPTIONAL REGULATOR YHJB-RELATED				helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b0795|UniProtKB=P75777	P75777	ybhG	PTHR32347:SF29	EFFLUX SYSTEM COMPONENT YKNX-RELATED	UPF0194 MEMBRANE PROTEIN YBHG		response to stimulus#GO:0050896;response to chemical#GO:0042221;response to antibiotic#GO:0046677			
ECOLI|EnsemblGenome=b3405|UniProtKB=P0AA16	P0AA16	ompR	PTHR48111:SF79	REGULATOR OF RPOS	DNA-BINDING DUAL TRANSCRIPTIONAL REGULATOR OMPR	transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b1452|UniProtKB=P76116	P76116	yncE	PTHR47197:SF3	PROTEIN NIRF	PROTEIN YWHK					
ECOLI|EnsemblGenome=b1838|UniProtKB=P55798	P55798	pphA	PTHR42850:SF10	METALLOPHOSPHOESTERASE	SERINE_THREONINE-PROTEIN PHOSPHATASE 1	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578	cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;RNA decapping#GO:0110154;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	hydrolase#PC00121;phosphatase#PC00181	
ECOLI|EnsemblGenome=b3327|UniProtKB=P41441	P41441	gspF	PTHR30012:SF0	GENERAL SECRETION PATHWAY PROTEIN	TYPE II SECRETION SYSTEM PROTEIN F-RELATED				transporter#PC00227	
ECOLI|EnsemblGenome=b3012|UniProtKB=Q46857	Q46857	dkgA	PTHR11732:SF542	ALDO/KETO REDUCTASE	METHYLGLYOXAL REDUCTASE DKGA	oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455	cellular response to chemical stimulus#GO:0070887;cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700;ketone metabolic process#GO:0042180;cellular detoxification of aldehyde#GO:0110095;cellular response to stimulus#GO:0051716;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;response to chemical#GO:0042221;cellular response to toxic substance#GO:0097237;aldehyde catabolic process#GO:0046185;detoxification#GO:0098754	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	reductase#PC00198;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b4348|UniProtKB=P05719	P05719	hsdS	PTHR43140:SF1	TYPE-1 RESTRICTION ENZYME ECOKI SPECIFICITY PROTEIN	TYPE I RESTRICTION ENZYME ECOKI SPECIFICITY SUBUNIT		primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;macromolecule modification#GO:0043412;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to other organism#GO:0051707;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;defense response#GO:0006952;response to external stimulus#GO:0009605	cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;endonuclease complex#GO:1905348		
ECOLI|EnsemblGenome=b0454|UniProtKB=P0AFP2	P0AFP2	atl	PTHR42942:SF1	6-O-METHYLGUANINE DNA METHYLTRANSFERASE	ALKYLTRANSFERASE-LIKE PROTEIN 1	nucleic acid binding#GO:0003676;binding#GO:0005488;damaged DNA binding#GO:0003684;DNA binding#GO:0003677	DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896		DNA methyltransferase#PC00013	
ECOLI|EnsemblGenome=b0224|UniProtKB=P0AA99	P0AA99	dpaA	PTHR36699:SF2	LD-TRANSPEPTIDASE	PEPTIDOGLYCAN MESO-DIAMINOPIMELIC ACID PROTEIN AMIDASE A	catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787	macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycosaminoglycan metabolic process#GO:0030203;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;peptidoglycan metabolic process#GO:0000270		cysteine protease#PC00081	
ECOLI|EnsemblGenome=b1440|UniProtKB=P76108	P76108	ydcS	PTHR30222:SF18	SPERMIDINE/PUTRESCINE-BINDING PERIPLASMIC PROTEIN	BIFUNCTIONAL POLYHYDROXYBUTYRATE SYNTHASE _ ABC TRANSPORTER PERIPLASMIC BINDING PROTEIN-RELATED	ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169	transport#GO:0006810;nitrogen compound transport#GO:0071705;localization#GO:0051179;establishment of localization#GO:0051234	periplasmic space#GO:0042597;extracellular region#GO:0005576;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313		
ECOLI|EnsemblGenome=b3526|UniProtKB=P37647	P37647	kdgK	PTHR43085:SF15	HEXOKINASE FAMILY MEMBER	2-DEHYDRO-3-DEOXYGLUCONOKINASE	carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773	cellular response to stress#GO:0033554;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;cellular response to stimulus#GO:0051716;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;DNA damage response#GO:0006974;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;response to stress#GO:0006950;monocarboxylic acid catabolic process#GO:0072329	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;carbohydrate kinase#PC00065;transferase#PC00220	
ECOLI|EnsemblGenome=b1135|UniProtKB=P75966	P75966	rluE	PTHR21600:SF85	MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE	RIBOSOMAL LARGE SUBUNIT PSEUDOURIDINE SYNTHASE E	isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866	metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613		RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b0212|UniProtKB=P0AC84	P0AC84	gloB	PTHR43705:SF1	HYDROXYACYLGLUTATHIONE HYDROLASE	HYDROXYACYLGLUTATHIONE HYDROLASE GLOB	hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790			hydrolase#PC00121	
ECOLI|EnsemblGenome=b3200|UniProtKB=P0ADV1	P0ADV1	lptA	PTHR36504:SF1	LIPOPOLYSACCHARIDE EXPORT SYSTEM PROTEIN LPTA	LIPOPOLYSACCHARIDE EXPORT SYSTEM PROTEIN LPTA	lipid transfer activity#GO:0120013;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319	transport#GO:0006810;carbohydrate derivative transport#GO:1901264;lipid localization#GO:0010876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;lipid transport#GO:0006869;localization#GO:0051179	external encapsulating structure#GO:0030312;membrane#GO:0016020;cell outer membrane#GO:0009279;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;periplasmic space#GO:0042597;extracellular region#GO:0005576;outer membrane#GO:0019867;outer membrane-bounded periplasmic space#GO:0030288		
ECOLI|EnsemblGenome=b0811|UniProtKB=P0AEQ3	P0AEQ3	glnH	PTHR35936:SF38	MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE F	GLUTAMINE-BINDING PERIPLASMIC PROTEIN	binding#GO:0005488;amino acid binding#GO:0016597		extracellular region#GO:0005576;periplasmic space#GO:0042597;cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288		
ECOLI|EnsemblGenome=b1088|UniProtKB=P0AB28	P0AB28	yceD	PTHR38099:SF1	LARGE RIBOSOMAL RNA SUBUNIT ACCUMULATION PROTEIN YCED	LARGE RIBOSOMAL RNA SUBUNIT ACCUMULATION PROTEIN YCED					
ECOLI|EnsemblGenome=b1801|UniProtKB=P0ABD1	P0ABD1	yeaV	PTHR30047:SF12	HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN-RELATED	BCCT-FAMILY TRANSPORTER	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b4064|UniProtKB=P0AF52	P0AF52	ghxP	PTHR43337:SF5	XANTHINE/URACIL PERMEASE C887.17-RELATED	GUANINE_HYPOXANTHINE PERMEASE GHXP	nucleobase transmembrane transporter activity#GO:0015205;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b1280|UniProtKB=P0AB58	P0AB58	lapB	PTHR12558:SF47	CELL DIVISION CYCLE 16,23,27	LIPOPOLYSACCHARIDE ASSEMBLY PROTEIN B				protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234	
ECOLI|EnsemblGenome=b2183|UniProtKB=P0AA43	P0AA43	rsuA	PTHR21600:SF19	MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE	RIBOSOMAL SMALL SUBUNIT PSEUDOURIDINE SYNTHASE A	catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853	metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b2008|UniProtKB=P33011	P33011	yeeA	PTHR30509:SF42	P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT-RELATED	INNER MEMBRANE PROTEIN YEEA			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b0019|UniProtKB=P13738	P13738	nhaA	PTHR30341:SF0	SODIUM ION/PROTON ANTIPORTER NHAA-RELATED	NA(+)_H(+) ANTIPORTER NHAA	monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;metal cation:proton antiporter activity#GO:0051139;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	secondary carrier transporter#PC00258;transporter#PC00227	
ECOLI|EnsemblGenome=b0792|UniProtKB=P0AFP9	P0AFP9	ybhR	PTHR30294:SF44	MEMBRANE COMPONENT OF ABC TRANSPORTER YHHJ-RELATED	MULTIDRUG ABC TRANSPORTER PERMEASE YBHR-RELATED			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b2410|UniProtKB=P39836	P39836	yfeH	PTHR18640:SF5	SOLUTE CARRIER FAMILY 10 MEMBER 7	SODIUM_BILE ACID COTRANSPORTER 7			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227;secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b1809|UniProtKB=P0AEB7	P0AEB7	yoaB	PTHR47328:SF2	FAMILY NOT NAMED	RUTC FAMILY PROTEIN YOAB		single-species biofilm formation#GO:0044010;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b2943|UniProtKB=P0AEP1	P0AEP1	galP	PTHR48023:SF9	D-XYLOSE-PROTON SYMPORTER-LIKE 2	GALACTOSE-PROTON SYMPORTER	symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804	cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085	membrane#GO:0016020;cellular anatomical structure#GO:0110165	primary active transporter#PC00068;transporter#PC00227	
ECOLI|EnsemblGenome=b4518|UniProtKB=P56614	P56614	ymdF	PTHR36569:SF4	FAMILY NOT NAMED	CYTOPLASMIC PROTEIN					
ECOLI|EnsemblGenome=b1640|UniProtKB=P77570	P77570	anmK	PTHR30605:SF0	ANHYDRO-N-ACETYLMURAMIC ACID KINASE	ANHYDRO-N-ACETYLMURAMIC ACID KINASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772			metabolite interconversion enzyme#PC00262;kinase#PC00137	
ECOLI|EnsemblGenome=b2170|UniProtKB=P33026	P33026	setB	PTHR23535:SF2	SUGAR EFFLUX TRANSPORTER A-RELATED	SUGAR EFFLUX TRANSPORTER A-RELATED	active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate transmembrane transporter activity#GO:0015144;symporter activity#GO:0015293;solute:proton symporter activity#GO:0015295	response to stimulus#GO:0050896;response to chemical#GO:0042221;carbohydrate transmembrane transport#GO:0034219;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular response to chemical stress#GO:0062197;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;carbohydrate transport#GO:0008643;cellular response to stress#GO:0033554;transport#GO:0006810;cellular response to chemical stimulus#GO:0070887	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b2731|UniProtKB=P19323	P19323	fhlA	PTHR32071:SF123	TRANSCRIPTIONAL REGULATORY PROTEIN	DNA-BINDING TRANSCRIPTIONAL ACTIVATOR HYFR-RELATED	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;double-stranded DNA binding#GO:0003690	regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252	protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991	DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b1133|UniProtKB=P25745	P25745	mnmA	PTHR11933:SF7	TRNA  5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE	TRNA-SPECIFIC 2-THIOURIDYLASE MNMA	sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824	macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;tRNA thio-modification#GO:0034227;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;tRNA wobble position uridine thiolation#GO:0002143;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987	catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytoplasm#GO:0005737;sulfurtransferase complex#GO:1990228;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991	RNA methyltransferase#PC00033	
ECOLI|EnsemblGenome=b1339|UniProtKB=P77744	P77744	abgR	PTHR30126:SF97	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR ABGR	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219		helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b1692|UniProtKB=P0A6D5	P0A6D5	ydiB	PTHR21089:SF1	SHIKIMATE DEHYDROGENASE	BIFUNCTIONAL 3-DEHYDROQUINATE DEHYDRATASE_SHIKIMATE DEHYDROGENASE, CHLOROPLASTIC	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491	small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283		dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	Chorismate biosynthesis#P02734>Shikimate dehydrogenase#P02873
ECOLI|EnsemblGenome=b4052|UniProtKB=P0ACB0	P0ACB0	dnaB	PTHR30153:SF2	REPLICATIVE DNA HELICASE DNAB	REPLICATIVE DNA HELICASE DNAB	ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543	DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA replication initiation#GO:0006270;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260	intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-DNA complex#GO:0032993;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;replisome#GO:0030894;replication fork#GO:0005657;cytosol#GO:0005829;chromosome#GO:0005694;DNA helicase complex#GO:0033202	DNA helicase#PC00011;DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b2017|UniProtKB=P69346	P69346	yefM	PTHR33713:SF6	ANTITOXIN YAFN-RELATED	ANTITOXIN YEFM	DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219			
ECOLI|EnsemblGenome=b0799|UniProtKB=P27296	P27296	dinG	PTHR11472:SF59	DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER	ATP-DEPENDENT DNA HELICASE DING	binding#GO:0005488;small molecule binding#GO:0036094;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;iron-sulfur cluster binding#GO:0051536;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;DNA helicase activity#GO:0003678	DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;SOS response#GO:0009432;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139		DNA helicase#PC00011;DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b2440|UniProtKB=P19636	P19636	eutC	PTHR39330:SF1	ETHANOLAMINE AMMONIA-LYASE LIGHT CHAIN	ETHANOLAMINE AMMONIA-LYASE SMALL SUBUNIT			catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991	metabolite interconversion enzyme#PC00262;lyase#PC00144	
ECOLI|EnsemblGenome=b3958|UniProtKB=P11446	P11446	argC	PTHR32338:SF10	N-ACETYL-GAMMA-GLUTAMYL-PHOSPHATE REDUCTASE, CHLOROPLASTIC-RELATED-RELATED	N-ACETYL-GAMMA-GLUTAMYL-PHOSPHATE REDUCTASE, CHLOROPLASTIC-RELATED	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491	cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;L-arginine biosynthetic process#GO:0006526;proteinogenic amino acid biosynthetic process#GO:0170038		reductase#PC00198;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1792|UniProtKB=P76243	P76243	yeaO	PTHR36849:SF1	CYTOPLASMIC PROTEIN-RELATED	DUF488 FAMILY PROTEIN					
ECOLI|EnsemblGenome=b4516|UniProtKB=P0CF10	P0CF10	insA4	PTHR47923:SF1	INSERTION ELEMENT IS1 1 PROTEIN INSA-RELATED	INSERTION ELEMENT IS1 1 PROTEIN INSA-RELATED		macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304			
ECOLI|EnsemblGenome=b0352|UniProtKB=P51020	P51020	mhpE	PTHR10277:SF9	HOMOCITRATE SYNTHASE-RELATED	4-HYDROXY-2-OXOVALERATE ALDOLASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746	amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;branched-chain amino acid biosynthetic process#GO:0009082;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436		transferase#PC00220	Phenylpropionate degradation#P02767>4-Hydroxy-2-ketovalerate aldolase#P03106;Leucine biosynthesis#P02749>2-Isopropylmalate synthase#P02999
ECOLI|EnsemblGenome=b0916|UniProtKB=P75843	P75843	ycaQ	PTHR30528:SF0	CYTOPLASMIC PROTEIN	INTERSTRAND DNA CROSS-LINK REPAIR GLYCOSYLASE	catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA N-glycosylase activity#GO:0019104;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097	response to stimulus#GO:0050896;interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554			
ECOLI|EnsemblGenome=b3826|UniProtKB=P27848	P27848	yigL	PTHR47267:SF4	FAMILY NOT NAMED	PHOSPHOSUGAR PHOSPHATASE YIGL	phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;magnesium ion binding#GO:0000287;cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167				
ECOLI|EnsemblGenome=b0761|UniProtKB=P0A9G8	P0A9G8	modE	PTHR30432:SF1	TRANSCRIPTIONAL REGULATOR MODE	DNA-BINDING TRANSCRIPTIONAL DUAL REGULATOR MODE	metal ion binding#GO:0046872;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;double-stranded DNA binding#GO:0003690;cation binding#GO:0043169;nucleic acid binding#GO:0003676;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transcription cis-regulatory region binding#GO:0000976;transition metal ion binding#GO:0046914;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355		DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b3542|UniProtKB=P0AEG1	P0AEG1	dppC	PTHR43386:SF28	OLIGOPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN APPC	D,D-DIPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN DDPC-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;dipeptide transmembrane transporter activity#GO:0071916;oligopeptide transmembrane transporter activity#GO:0035673		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b3790|UniProtKB=P27832	P27832	wecD	PTHR43877:SF9	AMINOALKYLPHOSPHONATE N-ACETYLTRANSFERASE-RELATED-RELATED	DTDP-FUCOSAMINE ACETYLTRANSFERASE	N-acetyltransferase activity#GO:0008080;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747				
ECOLI|EnsemblGenome=b3773|UniProtKB=P05827	P05827	ilvY	PTHR30126:SF81	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR ILVY	sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676	biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355		gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b0706|UniProtKB=P28916	P28916	ybfD	PTHR30298:SF0	H REPEAT-ASSOCIATED PREDICTED TRANSPOSASE	PROTEIN YBFL-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b0814|UniProtKB=P0A917	P0A917	ompX	PTHR35892:SF3	OUTER MEMBRANE PROTEIN PAGN-RELATED	OUTER MEMBRANE PROTEIN X			extracellular region#GO:0005576;outer membrane#GO:0019867;cell outer membrane#GO:0009279;membrane#GO:0016020;external encapsulating structure#GO:0030312;cell envelope#GO:0030313;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2828|UniProtKB=P60955	P60955	lgt	PTHR30589:SF0	PROLIPOPROTEIN DIACYLGLYCERYL TRANSFERASE	PHOSPHATIDYLGLYCEROL--PROLIPOPROTEIN DIACYLGLYCERYL TRANSFERASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757	cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipoprotein metabolic process#GO:0042157;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transferase#PC00220	
ECOLI|EnsemblGenome=b1773|UniProtKB=P77704	P77704	ydjI	PTHR30304:SF12	D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE	D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE SUBUNIT GATY-RELATED	aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824		cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	lyase#PC00144;aldolase#PC00044	
ECOLI|EnsemblGenome=b2320|UniProtKB=P05459	P05459	pdxB	PTHR42938:SF52	FORMATE DEHYDROGENASE 1	ERYTHRONATE-4-PHOSPHATE DEHYDROGENASE	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491	biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;pyridine-containing compound metabolic process#GO:0072524;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	dehydrogenase#PC00092;oxidoreductase#PC00176	Pyridoxal-5-phosphate biosynthesis#P02759>Erythronate-4-phosphate dehydrogenase#P03059
ECOLI|EnsemblGenome=b0268|UniProtKB=P75682	P75682	yagE	PTHR12128:SF28	DIHYDRODIPICOLINATE SYNTHASE	2-DEHYDRO-3-DEOXY-D-GLUCONATE ALDOLASE YAGE-RELATED	catalytic activity#GO:0003824;lyase activity#GO:0016829		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	lyase#PC00144	Lysine biosynthesis#P02751>Dihydrodipicolinate synthase#P03008
ECOLI|EnsemblGenome=b3450|UniProtKB=P10907	P10907	ugpC	PTHR43875:SF12	MALTODEXTRIN IMPORT ATP-BINDING PROTEIN MSMX	SN-GLYCEROL-3-PHOSPHATE IMPORT ATP-BINDING PROTEIN UGPC	ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;organophosphate ester transmembrane transporter activity#GO:0015605	carbohydrate derivative transport#GO:1901264;transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;organophosphate ester transport#GO:0015748;localization#GO:0051179	membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;ATP-binding cassette (ABC) transporter complex#GO:0043190;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533	ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b3150|UniProtKB=P64596	P64596	dolP	PTHR34606:SF4	BON DOMAIN-CONTAINING PROTEIN	OUTER MEMBRANE LIPOPROTEIN DOLP					
ECOLI|EnsemblGenome=b3728|UniProtKB=P0AG82	P0AG82	pstS	PTHR42996:SF1	PHOSPHATE-BINDING PROTEIN PSTS	PHOSPHATE-BINDING PROTEIN PSTS		inorganic anion transport#GO:0015698;phosphate ion transport#GO:0006817;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810		ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b4092|UniProtKB=P16692	P16692	phnP	PTHR42663:SF19	HYDROLASE C777.06C-RELATED-RELATED	PHOSPHORIBOSYL 1,2-CYCLIC PHOSPHATE PHOSPHODIESTERASE	catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578	phosphorus metabolic process#GO:0006793;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281		hydrolase#PC00121	
ECOLI|EnsemblGenome=b2088|UniProtKB=P0CF70	P0CF70	insE5	PTHR33215:SF6	PROTEIN DISTAL ANTENNA	TRANSPOSASE INSE FOR INSERTION SEQUENCE IS3A-RELATED					
ECOLI|EnsemblGenome=b0942|UniProtKB=P75859	P75859	ycbU	PTHR33420:SF5	FIMBRIAL SUBUNIT ELFA-RELATED	FIMBRIAL SUBUNIT		cell-substrate adhesion#GO:0031589;single-species biofilm formation#GO:0044010;cellular process#GO:0009987;cell adhesion#GO:0007155	cell projection#GO:0042995;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0847|UniProtKB=P60869	P60869	ybjL	PTHR30445:SF10	K(+)_H(+) ANTIPORTER SUBUNIT KHTT	TRANSPORT PROTEIN YBJL-RELATED			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b3570|UniProtKB=P27297	P27297	bax	PTHR40572:SF1	PROTEIN BAX	PROTEIN BAX					
ECOLI|EnsemblGenome=b1195|UniProtKB=P76011	P76011	ymgE	PTHR33884:SF3	UPF0410 PROTEIN YMGE	UPF0410 PROTEIN YMGE					
ECOLI|EnsemblGenome=b3384|UniProtKB=P00954	P00954	trpS	PTHR43766:SF1	TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL	TRYPTOPHAN--TRNA LIGASE	catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874	tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538		aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263	
ECOLI|EnsemblGenome=b2535|UniProtKB=P54901	P54901	csiE	PTHR30185:SF14	CRYPTIC BETA-GLUCOSIDE BGL OPERON ANTITERMINATOR	STATIONARY PHASE-INDUCIBLE PROTEIN CSIE-RELATED					
ECOLI|EnsemblGenome=b0927|UniProtKB=P75849	P75849	gloC	PTHR46233:SF5	HYDROXYACYLGLUTATHIONE HYDROLASE GLOC	HYDROXYACYLGLUTATHIONE HYDROLASE GLOC	hydrolase activity#GO:0016787;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	hydrolase#PC00121	
ECOLI|EnsemblGenome=b2609|UniProtKB=P0A7T3	P0A7T3	rpsP	PTHR12919:SF20	30S RIBOSOMAL PROTEIN S16	SMALL RIBOSOMAL SUBUNIT PROTEIN BS16M_BS16C	structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735		ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232	ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b1827|UniProtKB=P76268	P76268	kdgR	PTHR30136:SF7	HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY	HTH-TYPE TRANSCRIPTIONAL REGULATOR KDGR-RELATED	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519		helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b1392|UniProtKB=P76081	P76081	paaE	PTHR47354:SF8	NADH OXIDOREDUCTASE HCR	1,2-PHENYLACETYL-COA EPOXIDASE, SUBUNIT E	catalytic activity#GO:0003824;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536			oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3898|UniProtKB=P32153	P32153	frvX	PTHR32481:SF0	AMINOPEPTIDASE	AMINOPEPTIDASE YPDE-RELATED	peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237			metalloprotease#PC00153	
ECOLI|EnsemblGenome=b1677|UniProtKB=P69776	P69776	lpp	PTHR38763:SF1	MAJOR OUTER MEMBRANE PROLIPOPROTEIN LPP	MAJOR OUTER MEMBRANE LIPOPROTEIN LPP					
ECOLI|EnsemblGenome=b2788|UniProtKB=Q46915	Q46915	gudX	PTHR48080:SF1	D-GALACTONATE DEHYDRATASE-RELATED	GLUCARATE DEHYDRATASE-RELATED PROTEIN	catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836	small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436		dehydratase#PC00091	
ECOLI|EnsemblGenome=b4094|UniProtKB=P16690	P16690	phnN	PTHR23117:SF8	GUANYLATE KINASE-RELATED	RIBOSE 1,5-BISPHOSPHATE PHOSPHOKINASE PHNN	phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740	nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine ribonucleoside diphosphate metabolic process#GO:0009179;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;organophosphate biosynthetic process#GO:0090407;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	kinase#PC00137;transferase#PC00220	
ECOLI|EnsemblGenome=b1216|UniProtKB=P31801	P31801	chaA	PTHR37958:SF1	SODIUM-POTASSIUM/PROTON ANTIPORTER CHAA	SODIUM-POTASSIUM_PROTON ANTIPORTER CHAA	monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0141|UniProtKB=P37050	P37050	yadN	PTHR33420:SF3	FIMBRIAL SUBUNIT ELFA-RELATED	FIMBRIAL SUBUNIT ELFA					
ECOLI|EnsemblGenome=b1647|UniProtKB=P76187	P76187	ydhF	PTHR43364:SF1	NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED	OXIDOREDUCTASE YDHF			cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3729|UniProtKB=P17169	P17169	glmS	PTHR10937:SF19	GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING	GLUTAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING]	transaminase activity#GO:0008483;catalytic activity#GO:0003824;transferase activity#GO:0016740	organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;amino sugar metabolic process#GO:0006040;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;UDP-N-acetylglucosamine biosynthetic process#GO:0006048;UDP-N-acetylglucosamine metabolic process#GO:0006047;organophosphate biosynthetic process#GO:0090407	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	transaminase#PC00216	O-antigen biosynthesis#P02757>Fructose-6-phosphate aminotransferase#P03051;N-acetylglucosamine metabolism#P02756>Fructose-6-phosphate aminotransferase#P03042
ECOLI|EnsemblGenome=b4366|UniProtKB=P39404	P39404	bglJ	PTHR43214:SF31	TWO-COMPONENT RESPONSE REGULATOR	TRANSCRIPTIONAL ACTIVATOR PROTEIN BGLJ	transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252		helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b0118|UniProtKB=P36683	P36683	acnB	PTHR43160:SF4	ACONITATE HYDRATASE B	ACONITATE HYDRATASE B	carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;iron-sulfur cluster binding#GO:0051536;small molecule binding#GO:0036094;catalytic activity#GO:0003824;binding#GO:0005488	monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;aerobic respiration#GO:0009060;fatty acid catabolic process#GO:0009062;short-chain fatty acid catabolic process#GO:0019626;cellular respiration#GO:0045333;oxoacid metabolic process#GO:0043436	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	hydratase#PC00120;lyase#PC00144	
ECOLI|EnsemblGenome=b3640|UniProtKB=P06968	P06968	dut	PTHR11241:SF0	DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE	DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE	hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;nucleoside triphosphate diphosphatase activity#GO:0047429;binding#GO:0005488;small molecule binding#GO:0036094;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ion binding#GO:0043167;magnesium ion binding#GO:0000287;cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787	phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;nucleoside monophosphate biosynthetic process#GO:0009124;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;nucleotide biosynthetic process#GO:0009165;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086		phosphatase#PC00181;hydrolase#PC00121	De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUTP pyrophosphatase#P02918
ECOLI|EnsemblGenome=b1134|UniProtKB=P0AEI6	P0AEI6	nudJ	PTHR43222:SF11	NUDIX HYDROLASE 23	PHOSPHATASE NUDJ	pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787			hydrolase#PC00121	
ECOLI|EnsemblGenome=b4314|UniProtKB=P04128	P04128	fimA	PTHR33420:SF12	FIMBRIAL SUBUNIT ELFA-RELATED	FIMBRIN-LIKE PROTEIN FIMI-RELATED		cellular process#GO:0009987;cell adhesion#GO:0007155;single-species biofilm formation#GO:0044010;cell-substrate adhesion#GO:0031589	cellular anatomical structure#GO:0110165;cell projection#GO:0042995		
ECOLI|EnsemblGenome=b2465|UniProtKB=P33570	P33570	tktB	PTHR43522:SF13	TRANSKETOLASE	TRANSKETOLASE 2	catalytic activity#GO:0003824;transferase activity#GO:0016740;transketolase or transaldolase activity#GO:0016744;transketolase activity#GO:0004802	nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;pentose-phosphate shunt#GO:0006098;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;transketolase#PC00221;transferase#PC00220	
ECOLI|EnsemblGenome=b3781|UniProtKB=P0AA25	P0AA25	trxA	PTHR45663:SF15	GEO12009P1	THIOREDOXIN Y1, CHLOROPLASTIC-RELATED	protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824	cellular homeostasis#GO:0019725;homeostatic process#GO:0042592;cell redox homeostasis#GO:0045454	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	Hypoxia response via HIF activation#P00030>Thioredoxin#P00825
ECOLI|EnsemblGenome=b3721|UniProtKB=P11988	P11988	bglB	PTHR10353:SF349	GLYCOSYL HYDROLASE	6-PHOSPHO-BETA-GLUCOSIDASE ASCB-RELATED	catalytic activity#GO:0003824;glucosidase activity#GO:0015926;beta-glucosidase activity#GO:0008422;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787	primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;hydrolase#PC00121;glycosidase#PC00110	
ECOLI|EnsemblGenome=b0887|UniProtKB=P29018	P29018	cydD	PTHR24221:SF261	ATP-BINDING CASSETTE SUB-FAMILY B	GLUTATHIONE_L-CYSTEINE TRANSPORT SYSTEM ATP-BINDING_PERMEASE PROTEIN CYDD	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399	transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810		ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b3634|UniProtKB=P0A6I6	P0A6I6	coaD	PTHR21342:SF1	PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE	PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE	nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772	purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293		acetyltransferase#PC00038;transferase#PC00220	Coenzyme A biosynthesis#P02736>Pantetheine-phosphate adenyltransferase#P02886
ECOLI|EnsemblGenome=b0211|UniProtKB=P0AEZ7	P0AEZ7	mltD	PTHR33734:SF22	LYSM DOMAIN-CONTAINING GPI-ANCHORED PROTEIN 2	MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE D	peptidoglycan lytic transglycosylase activity#GO:0008933;catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783;carbon-oxygen lyase activity, acting on polysaccharides#GO:0016837;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829	carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;metabolic process#GO:0008152;peptidoglycan metabolic process#GO:0000270;aminoglycan metabolic process#GO:0006022;glycosaminoglycan metabolic process#GO:0030203;macromolecule metabolic process#GO:0043170			
ECOLI|EnsemblGenome=b3199|UniProtKB=P0ADV9	P0ADV9	lptC	PTHR37481:SF1	LIPOPOLYSACCHARIDE EXPORT SYSTEM PROTEIN LPTC	LIPOPOLYSACCHARIDE EXPORT SYSTEM PROTEIN LPTC	lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;lipid transfer activity#GO:0120013	lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234;lipid localization#GO:0010876;macromolecule localization#GO:0033036;carbohydrate derivative transport#GO:1901264;transport#GO:0006810	outer membrane-bounded periplasmic space#GO:0030288;periplasmic space#GO:0042597;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell envelope#GO:0030313;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b2305|UniProtKB=P77768	P77768	rpnB	PTHR34611:SF5	INACTIVE RECOMBINATION-PROMOTING NUCLEASE-LIKE PROTEIN RPNE	RECOMBINATION-PROMOTING NUCLEASE RPNA-RELATED	hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519	cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170			
ECOLI|EnsemblGenome=b3065|UniProtKB=P68679	P68679	rpsU	PTHR21109:SF22	MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S21	SMALL RIBOSOMAL SUBUNIT PROTEIN BS21				ribosomal protein#PC00202;translational protein#PC00263	
ECOLI|EnsemblGenome=b1321|UniProtKB=P76046	P76046	ycjX	PTHR38605:SF1	ATPASE-RELATED	RAS-LIKE GTPASE YCJX	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111				
ECOLI|EnsemblGenome=b3193|UniProtKB=P64604	P64604	mlaD	PTHR33371:SF4	INTERMEMBRANE PHOSPHOLIPID TRANSPORT SYSTEM BINDING PROTEIN MLAD-RELATED	INTERMEMBRANE PHOSPHOLIPID TRANSPORT SYSTEM BINDING PROTEIN MLAD	lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104	cellular process#GO:0009987;macromolecule localization#GO:0033036;cellular component organization#GO:0016043;membrane organization#GO:0061024;phospholipid transport#GO:0015914;intermembrane phospholipid transfer#GO:0120010;lipid transport#GO:0006869;organophosphate ester transport#GO:0015748;transport#GO:0006810;lipid localization#GO:0010876;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b3997|UniProtKB=P29680	P29680	hemE	PTHR21091:SF169	METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED	UROPORPHYRINOGEN DECARBOXYLASE	carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;lyase activity#GO:0016829	porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;porphyrin-containing compound biosynthetic process#GO:0006779;cellular process#GO:0009987;heme biosynthetic process#GO:0006783;pigment metabolic process#GO:0042440;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058;tetrapyrrole biosynthetic process#GO:0033014	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	methyltransferase#PC00155	Heme biosynthesis#P02746>Uroporphyrinogen decarboxylase#P02975
ECOLI|EnsemblGenome=b2618|UniProtKB=P52119	P52119	ratB	PTHR37483:SF1	UPF0125 PROTEIN RATB	UPF0125 PROTEIN RATB					
ECOLI|EnsemblGenome=b3998|UniProtKB=P68739	P68739	nfi	PTHR28511:SF4	ENDONUCLEASE V	ENDONUCLEASE V	RNA binding#GO:0003723;hydrolase activity#GO:0016787;nucleic acid binding#GO:0003676;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity, acting on DNA#GO:0140097;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;single-stranded RNA binding#GO:0003727				
ECOLI|EnsemblGenome=b1496|UniProtKB=P31826	P31826	yddA	PTHR11384:SF72	ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER	INNER MEMBRANE ABC TRANSPORTER ATP-BINDING PROTEIN YDDA	active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b2220|UniProtKB=Q06065	Q06065	atoC	PTHR32071:SF117	TRANSCRIPTIONAL REGULATORY PROTEIN	PTS-DEPENDENT DIHYDROXYACETONE KINASE OPERON REGULATORY PROTEIN-RELATED	double-stranded DNA binding#GO:0003690;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090	protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993	DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b3052|UniProtKB=P76658	P76658	hldE	PTHR46969:SF1	BIFUNCTIONAL PROTEIN HLDE	BIFUNCTIONAL PROTEIN HLDE	nucleotidyltransferase activity#GO:0016779;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		
ECOLI|EnsemblGenome=b2936|UniProtKB=P25894	P25894	loiP	PTHR22726:SF4	METALLOENDOPEPTIDASE OMA1	METALLOPROTEASE LOIP	metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096	primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170	cellular anatomical structure#GO:0110165;membrane#GO:0016020	protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190	
ECOLI|EnsemblGenome=b2734|UniProtKB=P55799	P55799	pphB	PTHR42850:SF8	METALLOPHOSPHOESTERASE	SERINE_THREONINE-PROTEIN PHOSPHATASE 2	hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462	nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;RNA decapping#GO:0110154	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	hydrolase#PC00121;phosphatase#PC00181	
ECOLI|EnsemblGenome=b3606|UniProtKB=P0AGJ7	P0AGJ7	trmL	PTHR42971:SF2	TRNA (CYTIDINE(34)-2'-O)-METHYLTRANSFERASE	TRNA (CYTIDINE(34)-2'-O)-METHYLTRANSFERASE		primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;methylation#GO:0032259;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033		RNA metabolism protein#PC00031;RNA methyltransferase#PC00033	
ECOLI|EnsemblGenome=b1534|UniProtKB=P31126	P31126	ydeE	PTHR23535:SF1	SUGAR EFFLUX TRANSPORTER A-RELATED	MFS FAMILY TRANSPORT PROTEIN	oligopeptide transmembrane transporter activity#GO:0035673;dipeptide transmembrane transporter activity#GO:0071916;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	peptide transport#GO:0015833;nitrogen compound transport#GO:0071705;oligopeptide transmembrane transport#GO:0035672;cellular process#GO:0009987;localization#GO:0051179;dipeptide transport#GO:0042938;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;oligopeptide transport#GO:0006857;transport#GO:0006810	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b4112|UniProtKB=P30844	P30844	basS	PTHR45436:SF7	SENSOR HISTIDINE KINASE YKOH	SENSOR PROTEIN BASS		signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;phosphorelay signal transduction system#GO:0000160;intracellular signal transduction#GO:0035556;cell communication#GO:0007154	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	histidine kinase receptor of two-component system#PC00265;transmembrane signal receptor#PC00197	
ECOLI|EnsemblGenome=b3685|UniProtKB=P60872	P60872	yidE	PTHR30445:SF8	K(+)_H(+) ANTIPORTER SUBUNIT KHTT	TRANSPORT PROTEIN YIDE-RELATED			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b0330|UniProtKB=P77743	P77743	prpR	PTHR32071:SF57	TRANSCRIPTIONAL REGULATORY PROTEIN	PROPIONATE CATABOLISM OPERON REGULATORY PROTEIN	double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription activator activity#GO:0001216;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355	protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991	DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b2022|UniProtKB=P06987	P06987	hisB	PTHR23133:SF2	IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE HIS7	IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE	hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824	carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;aromatic amino acid biosynthetic process#GO:0009073;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038		lyase#PC00144;dehydratase#PC00091	Histidine biosynthesis#P02747>Imidazol glycerol phosphate dehydratase#P02984
ECOLI|EnsemblGenome=b0561|UniProtKB=P77699	P77699	tfaD	PTHR34413:SF2	PROPHAGE TAIL FIBER ASSEMBLY PROTEIN HOMOLOG TFAE-RELATED-RELATED	PROPHAGE TAIL FIBER ASSEMBLY PROTEIN HOMOLOG TFAE-RELATED				chaperone#PC00072	
ECOLI|EnsemblGenome=b1209|UniProtKB=P61320	P61320	lolB	PTHR30634:SF16	OUTER MEMBRANE LOLAB LIPOPROTEIN INSERTION APPARATUS	OUTER-MEMBRANE LIPOPROTEIN LOLB				transporter#PC00227	
ECOLI|EnsemblGenome=b1944|UniProtKB=P0ABX8	P0ABX8	fliL	PTHR35091:SF2	FLAGELLAR PROTEIN FLIL	FLAGELLAR PROTEIN FLIL		bacterial-type flagellum-dependent swarming motility#GO:0071978;archaeal or bacterial-type flagellum-dependent cell motility#GO:0097588;cellular process#GO:0009987;cilium or flagellum-dependent cell motility#GO:0001539;cell motility#GO:0048870;bacterial-type flagellum-dependent cell motility#GO:0071973		structural protein#PC00211	
ECOLI|EnsemblGenome=b1010|UniProtKB=P0AFQ5	P0AFQ5	rutC	PTHR11803:SF58	2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA	2-IMINOBUTANOATE_2-IMINOPROPANOATE DEAMINASE-RELATED	catalytic activity#GO:0003824;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787		cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	hydrolase#PC00121;deaminase#PC00088;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0273|UniProtKB=P06960	P06960	argF	PTHR45753:SF4	ORNITHINE CARBAMOYLTRANSFERASE, MITOCHONDRIAL	ORNITHINE CARBAMOYLTRANSFERASE SUBUNIT F-RELATED	catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741	carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;L-arginine biosynthetic process#GO:0006526;proteinogenic amino acid biosynthetic process#GO:0170038		transferase#PC00220	Arginine biosynthesis#P02728>Ornithine carbamoyl transferase#P02846
ECOLI|EnsemblGenome=b2281|UniProtKB=P0AFD6	P0AFD6	nuoI	PTHR10849:SF36	NADH DEHYDROGENASE  UBIQUINONE  IRON-SULFUR PROTEIN 8, MITOCHONDRIAL	NADH-QUINONE OXIDOREDUCTASE SUBUNIT I	catalytic activity#GO:0003824;NADH dehydrogenase activity#GO:0003954;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651	metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271	oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2892|UniProtKB=P21893	P21893	recJ	PTHR30255:SF2	SINGLE-STRANDED-DNA-SPECIFIC EXONUCLEASE RECJ	SINGLE-STRANDED-DNA-SPECIFIC EXONUCLEASE RECJ	exonuclease activity#GO:0004527;hydrolase activity#GO:0016787;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA exonuclease activity#GO:0004529;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097	DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139		exodeoxyribonuclease#PC00098	
ECOLI|EnsemblGenome=b3434|UniProtKB=P67143	P67143	yhgN	PTHR33508:SF10	UPF0056 MEMBRANE PROTEIN YHCE	UPF0056 INNER MEMBRANE PROTEIN YHGN			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b0177|UniProtKB=P0A940	P0A940	bamA	PTHR12815:SF23	SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER	OUTER MEMBRANE PROTEIN ASSEMBLY FACTOR BAMA		intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;cellular component assembly#GO:0022607;protein insertion into membrane#GO:0051205;localization within membrane#GO:0051668;external encapsulating structure organization#GO:0045229;localization#GO:0051179;cellular localization#GO:0051641;membrane assembly#GO:0071709;cellular component organization#GO:0016043	membrane#GO:0016020;cell outer membrane#GO:0009279;membrane protein complex#GO:0098796;external encapsulating structure#GO:0030312;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;extracellular region#GO:0005576;outer membrane#GO:0019867;extracellular protein-containing complex#GO:0140392;side of membrane#GO:0098552		
ECOLI|EnsemblGenome=b0903|UniProtKB=P09373	P09373	pflB	PTHR30191:SF0	FORMATE ACETYLTRANSFERASE	FORMATE ACETYLTRANSFERASE 1	acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	transferase#PC00220;acetyltransferase#PC00038	
ECOLI|EnsemblGenome=b0958|UniProtKB=P0AFZ5	P0AFZ5	sulA	PTHR35369:SF4	BLR3025 PROTEIN-RELATED	CELL DIVISION INHIBITOR SULA		cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896			
ECOLI|EnsemblGenome=b2177|UniProtKB=P33913	P33913	yejA	PTHR30290:SF64	PERIPLASMIC BINDING COMPONENT OF ABC TRANSPORTER	OLIGOPEPTIDE-BINDING PROTEIN YEJA	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	transport#GO:0006810;nitrogen compound transport#GO:0071705;peptide transport#GO:0015833;establishment of localization#GO:0051234;localization#GO:0051179	cell envelope#GO:0030313;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;periplasmic space#GO:0042597;extracellular region#GO:0005576	transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b1584|UniProtKB=P0A951	P0A951	speG	PTHR43415:SF6	SPERMIDINE N(1)-ACETYLTRANSFERASE	SPERMIDINE N(1)-ACETYLTRANSFERASE	N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747			transferase#PC00220;acetyltransferase#PC00038	
ECOLI|EnsemblGenome=b3652|UniProtKB=P24230	P24230	recG	PTHR47964:SF1	ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC	ATP-DEPENDENT DNA HELICASE HOMOLOG RECG1, CHLOROPLASTIC_MITOCHONDRIAL	ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824	cellular response to stimulus#GO:0051716;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170		DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b2722|UniProtKB=P16430	P16430	hycD	PTHR43359:SF1	FORMATE HYDROGENLYASE SUBUNIT 4	FORMATE HYDROGENLYASE SUBUNIT 4-RELATED		electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;anaerobic electron transport chain#GO:0019645;anaerobic respiration#GO:0009061;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333	catalytic complex#GO:1902494;cell periphery#GO:0071944;oxidoreductase complex#GO:1990204;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991	oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3623|UniProtKB=P27242	P27242	waaU	PTHR30160:SF1	TETRAACYLDISACCHARIDE 4'-KINASE-RELATED	LIPOPOLYSACCHARIDE HEPTOSYLTRANSFERASE 3-RELATED	glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824	carbohydrate metabolic process#GO:0005975;lipopolysaccharide core region biosynthetic process#GO:0009244;lipopolysaccharide biosynthetic process#GO:0009103;liposaccharide metabolic process#GO:1903509;polysaccharide metabolic process#GO:0005976;primary metabolic process#GO:0044238;lipopolysaccharide metabolic process#GO:0008653;oligosaccharide biosynthetic process#GO:0009312;polysaccharide biosynthetic process#GO:0000271;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;lipid biosynthetic process#GO:0008610;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;oligosaccharide metabolic process#GO:0009311;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;lipid metabolic process#GO:0006629;metabolic process#GO:0008152	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	kinase#PC00137;carbohydrate kinase#PC00065	
ECOLI|EnsemblGenome=b3786|UniProtKB=P27828	P27828	wecB	PTHR43174:SF2	UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE	UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE	isomerase activity#GO:0016853;racemase and epimerase activity#GO:0016854;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;catalytic activity#GO:0003824	primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;polysaccharide metabolic process#GO:0005976;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975;carbohydrate biosynthetic process#GO:0016051;metabolic process#GO:0008152;polysaccharide biosynthetic process#GO:0000271;macromolecule metabolic process#GO:0043170	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	epimerase/racemase#PC00096	
ECOLI|EnsemblGenome=b2538|UniProtKB=P0ABR5	P0ABR5	hcaE	PTHR43756:SF1	CHOLINE MONOOXYGENASE, CHLOROPLASTIC	3-PHENYLPROPIONATE_CINNAMIC ACID DIOXYGENASE SUBUNIT ALPHA				oxygenase#PC00177;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b4254|UniProtKB=P04391	P04391	argI	PTHR45753:SF4	ORNITHINE CARBAMOYLTRANSFERASE, MITOCHONDRIAL	ORNITHINE CARBAMOYLTRANSFERASE SUBUNIT F-RELATED	transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;L-arginine biosynthetic process#GO:0006526;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520		transferase#PC00220	Arginine biosynthesis#P02728>Ornithine carbamoyl transferase#P02846
ECOLI|EnsemblGenome=b0318|UniProtKB=P77736	P77736	yahD	PTHR24184:SF11	SI:CH211-189E2.2	WD40 REPEAT-CONTAINING PROTEIN					
ECOLI|EnsemblGenome=b0591|UniProtKB=P24077	P24077	entS	PTHR23513:SF9	INTEGRAL MEMBRANE EFFLUX PROTEIN-RELATED	ENTEROBACTIN EXPORTER ENTS	efflux transmembrane transporter activity#GO:0015562;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	response to antibiotic#GO:0046677;response to chemical#GO:0042221;response to stimulus#GO:0050896	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b1856|UniProtKB=P0AFS9	P0AFS9	mepM	PTHR21666:SF292	PEPTIDASE-RELATED	MUREIN DD-ENDOPEPTIDASE MEPM				protease#PC00190;metalloprotease#PC00153	
ECOLI|EnsemblGenome=b2716|UniProtKB=P24240	P24240	ascB	PTHR10353:SF349	GLYCOSYL HYDROLASE	6-PHOSPHO-BETA-GLUCOSIDASE ASCB-RELATED	hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;beta-glucosidase activity#GO:0008422;glucosidase activity#GO:0015926;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787	cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;carbohydrate catabolic process#GO:0016052	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;hydrolase#PC00121;glycosidase#PC00110	
ECOLI|EnsemblGenome=b3177|UniProtKB=P0AC13	P0AC13	folP	PTHR20941:SF11	FOLATE SYNTHESIS PROTEINS	DIHYDROPTEROATE SYNTHASE	transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824	tetrahydrofolate metabolic process#GO:0046653;metabolic process#GO:0008152;tetrahydrofolate biosynthetic process#GO:0046654;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;biosynthetic process#GO:0009058;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		Tetrahydrofolate biosynthesis#P02742>Dihydropteroate synthase#P02945
ECOLI|EnsemblGenome=b2078|UniProtKB=P30847	P30847	baeS	PTHR43711:SF1	TWO-COMPONENT HISTIDINE KINASE	HISTIDINE KINASE	protein kinase activity#GO:0004672;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;transferase activity#GO:0016740;phosphorelay sensor kinase activity#GO:0000155;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;protein histidine kinase activity#GO:0004673;catalytic activity, acting on a protein#GO:0140096	cell communication#GO:0007154;intracellular signal transduction#GO:0035556;phosphorelay signal transduction system#GO:0000160;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transmembrane signal receptor#PC00197;histidine kinase receptor of two-component system#PC00265	
ECOLI|EnsemblGenome=b0167|UniProtKB=P27249	P27249	glnD	PTHR47320:SF1	BIFUNCTIONAL URIDYLYLTRANSFERASE/URIDYLYL-REMOVING ENZYME	BIFUNCTIONAL URIDYLYLTRANSFERASE_URIDYLYL-REMOVING ENZYME					
ECOLI|EnsemblGenome=b3671|UniProtKB=P08142	P08142	ilvB	PTHR18968:SF170	THIAMINE PYROPHOSPHATE ENZYMES	ACETOLACTATE SYNTHASE ISOZYME 1 LARGE SUBUNIT	binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;transferase activity#GO:0016740;catalytic activity#GO:0003824;transketolase or transaldolase activity#GO:0016744;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;branched-chain amino acid biosynthetic process#GO:0009082;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520	transferase complex#GO:1990234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	metabolite interconversion enzyme#PC00262;ligase#PC00142	Isoleucine biosynthesis#P02748>Acetolactate synthase#P02997;Valine biosynthesis#P02785>Acetolactate synthase#P03216
ECOLI|EnsemblGenome=b0025|UniProtKB=P0AG40	P0AG40	ribF	PTHR22749:SF6	RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE	BIFUNCTIONAL RIBOFLAVIN KINASE_FMN ADENYLYLTRANSFERASE	phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824	ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;flavin-containing compound metabolic process#GO:0042726;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165			Flavin biosynthesis#P02741>Riboflavin kinase#P02934;Flavin biosynthesis#P02741>FAD synthetase#P02936
ECOLI|EnsemblGenome=b2413|UniProtKB=P0A6J3	P0A6J3	cysZ	PTHR37468:SF1	SULFATE TRANSPORTER CYSZ	SULFATE TRANSPORTER CYSZ	active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:proton symporter activity#GO:0015295	carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b3615|UniProtKB=P11290	P11290	yibD	PTHR22916:SF51	GLYCOSYLTRANSFERASE	GLYCOSYLTRANSFERASE EPSH-RELATED	glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;glucuronosyltransferase activity#GO:0015020;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758			glycosyltransferase#PC00111;transferase#PC00220	
ECOLI|EnsemblGenome=b3105|UniProtKB=P67660	P67660	yhaJ	PTHR30126:SF22	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR YHAJ-RELATED	sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219		helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b0408|UniProtKB=P0AG90	P0AG90	secD	PTHR30081:SF1	PROTEIN-EXPORT MEMBRANE PROTEIN SEC	PROTEIN TRANSLOCASE SUBUNIT SECD		localization#GO:0051179;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein transport#GO:0015031;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;transport#GO:0006810	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1582|UniProtKB=P76169	P76169	ynfA	PTHR36116:SF1	UPF0060 MEMBRANE PROTEIN YNFA	UPF0060 MEMBRANE PROTEIN YNFA			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2990|UniProtKB=P0AAM7	P0AAM7	hybG	PTHR35177:SF2	HYDROGENASE MATURATION FACTOR HYBG	HYDROGENASE MATURATION FACTOR HYBG	transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872;iron ion binding#GO:0005506	primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538			
ECOLI|EnsemblGenome=b4039|UniProtKB=P26602	P26602	ubiC	PTHR38683:SF1	CHORISMATE PYRUVATE-LYASE	CHORISMATE PYRUVATE-LYASE	lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824	small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;ubiquinone biosynthetic process#GO:0006744;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ketone metabolic process#GO:0042180	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	lyase#PC00144	
ECOLI|EnsemblGenome=b2277|UniProtKB=P0AFE8	P0AFE8	nuoM	PTHR43507:SF1	NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4	NADH-QUINONE OXIDOREDUCTASE SUBUNIT M	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651;binding#GO:0005488;small molecule binding#GO:0036094;catalytic activity#GO:0003824;NADH dehydrogenase activity#GO:0003954	generation of precursor metabolites and energy#GO:0006091;transport#GO:0006810;metabolic process#GO:0008152;aerobic respiration#GO:0009060;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;proton transmembrane transport#GO:1902600;localization#GO:0051179;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220		oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1994|UniProtKB=P0CE53	P0CE53	insH6	PTHR35604:SF2	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	TRANSPOSASE INSH FOR INSERTION SEQUENCE ELEMENT IS5A-RELATED	catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824	DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b3985|UniProtKB=P0A7J3	P0A7J3	rplJ	PTHR11560:SF16	39S RIBOSOMAL PROTEIN L10, MITOCHONDRIAL	LARGE RIBOSOMAL SUBUNIT PROTEIN UL10	structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198	macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170	intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934	translational protein#PC00263;ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b1123|UniProtKB=P0AFK9	P0AFK9	potD	PTHR30222:SF17	SPERMIDINE/PUTRESCINE-BINDING PERIPLASMIC PROTEIN	SPERMIDINE_PUTRESCINE-BINDING PERIPLASMIC PROTEIN		transport#GO:0006810;nitrogen compound transport#GO:0071705;localization#GO:0051179;establishment of localization#GO:0051234			
ECOLI|EnsemblGenome=b2246|UniProtKB=P76470	P76470	rhmT	PTHR43791:SF30	PERMEASE-RELATED	INNER MEMBRANE TRANSPORT PROTEIN RHMT	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	primary active transporter#PC00068	
ECOLI|EnsemblGenome=b0957|UniProtKB=P0A910	P0A910	ompA	PTHR30128:SF84	OUTER MEMBRANE PROTEIN, OMPA-RELATED	OUTER MEMBRANE PROTEIN A			cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;external encapsulating structure#GO:0030312;membrane#GO:0016020;cell outer membrane#GO:0009279;outer membrane#GO:0019867;extracellular region#GO:0005576		
ECOLI|EnsemblGenome=b0381|UniProtKB=P0A6J8	P0A6J8	ddlA	PTHR23132:SF25	D-ALANINE--D-ALANINE LIGASE	D-ALANINE--D-ALANINE LIGASE A	ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824	peptidoglycan-based cell wall biogenesis#GO:0009273;peptidoglycan metabolic process#GO:0000270;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycosaminoglycan biosynthetic process#GO:0006024;cellular component organization or biogenesis#GO:0071840;cell wall macromolecule biosynthetic process#GO:0044038;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;cell wall organization or biogenesis#GO:0071554;biosynthetic process#GO:0009058;aminoglycan metabolic process#GO:0006022;cell wall biogenesis#GO:0042546;cell wall macromolecule metabolic process#GO:0044036;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan metabolic process#GO:0030203;peptidoglycan biosynthetic process#GO:0009252	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;ligase#PC00142	Peptidoglycan biosynthesis#P02763>D-alanine-D-alanine ligase#P03091
ECOLI|EnsemblGenome=b3642|UniProtKB=P0A7E3	P0A7E3	pyrE	PTHR46683:SF1	OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED	OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED	transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757	organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carbohydrate derivative biosynthetic process#GO:1901137;pyrimidine nucleobase metabolic process#GO:0006206;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	transferase#PC00220	De novo pyrimidine ribonucleotides biosythesis#P02740>Orotate phosphoribosyltransferase#P02922
ECOLI|EnsemblGenome=b3734|UniProtKB=P0ABB0	P0ABB0	atpA	PTHR48082:SF2	ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL	ATP SYNTHASE F(1) COMPLEX SUBUNIT ALPHA, MITOCHONDRIAL	proton channel activity#GO:0015252;nucleotide binding#GO:0000166;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;monoatomic ion channel activity#GO:0005216;heterocyclic compound binding#GO:1901363;monoatomic ion transmembrane transporter activity#GO:0015075;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;ligase activity#GO:0016874;transporter activity#GO:0005215;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;proton transmembrane transporter activity#GO:0015078;carbohydrate derivative binding#GO:0097367;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265	purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;organophosphate biosynthetic process#GO:0090407;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ATP biosynthetic process#GO:0006754;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522	respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;proton-transporting ATP synthase complex#GO:0045259;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;catalytic complex#GO:1902494;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351	primary active transporter#PC00068;ATP synthase#PC00002	ATP synthesis#P02721>F1 alpha#P02791
ECOLI|EnsemblGenome=b2279|UniProtKB=P0AFE4	P0AFE4	nuoK	PTHR11434:SF16	NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT ND4L	NAD(P)H-QUINONE OXIDOREDUCTASE SUBUNIT 4L, CHLOROPLASTIC				oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0713|UniProtKB=P75746	P75746	pxpA	PTHR30292:SF0	UNCHARACTERIZED PROTEIN YBGL-RELATED	5-OXOPROLINASE SUBUNIT A					
ECOLI|EnsemblGenome=b4480|UniProtKB=P0A8R9	P0A8R9	hdfR	PTHR30579:SF8	TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR HDFR	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141		gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b1828|UniProtKB=P76269	P76269	yebQ	PTHR23501:SF5	MAJOR FACILITATOR SUPERFAMILY	DRUG RESISTANCE TRANSPORTER, EMRB_QACA SUBFAMILY	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b3952|UniProtKB=P32675	P32675	pflC	PTHR30352:SF4	PYRUVATE FORMATE-LYASE-ACTIVATING ENZYME	PYRUVATE FORMATE-LYASE 2-ACTIVATING ENZYME	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824				
ECOLI|EnsemblGenome=b4252|UniProtKB=P0AF96	P0AF96	tabA	PTHR34986:SF4	EVOLVED BETA-GALACTOSIDASE SUBUNIT BETA	EVOLVED BETA-GALACTOSIDASE SUBUNIT BETA-RELATED		single-species biofilm formation#GO:0044010;cellular process#GO:0009987	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	galactosidase#PC00104;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1907|UniProtKB=P0AAD4	P0AAD4	tyrP	PTHR46997:SF2	LOW AFFINITY TRYPTOPHAN PERMEASE-RELATED	TYROSINE-SPECIFIC TRANSPORT SYSTEM	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	transport#GO:0006810;amino acid transport#GO:0006865;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2897|UniProtKB=P64559	P64559	sdhE	PTHR39585:SF1	FAD ASSEMBLY FACTOR SDHE	FAD ASSEMBLY FACTOR SDHE		protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;metabolic process#GO:0008152		chaperone#PC00072	
ECOLI|EnsemblGenome=b3753|UniProtKB=P0ACQ0	P0ACQ0	rbsR	PTHR30146:SF145	LACI-RELATED TRANSCRIPTIONAL REPRESSOR	RIBOSE OPERON REPRESSOR	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789		Lambda repressor-like transcription factor#PC00245;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b4108|UniProtKB=P0AFJ1	P0AFJ1	yjdM	PTHR30305:SF3	PROTEIN YJDM-RELATED	PHOSPHONOACETATE HYDROLASE YJDM			cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b3040|UniProtKB=P0A8H3	P0A8H3	zupT	PTHR11040:SF234	ZINC/IRON TRANSPORTER	ZINC TRANSPORTER ZUPT	zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873		cellular anatomical structure#GO:0110165;membrane#GO:0016020	secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b3651|UniProtKB=P0AGJ2	P0AGJ2	trmH	PTHR43453:SF1	RRNA METHYLASE-LIKE	TRNA_RRNA METHYLTRANSFERASE SPOU TYPE DOMAIN-CONTAINING PROTEIN		nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396		RNA methyltransferase#PC00033;RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b3584|UniProtKB=P37681	P37681	yiaT	PTHR38776:SF1	MLTA-INTERACTING PROTEIN-RELATED	MLTA-INTERACTING PROTEIN-RELATED		cell wall organization or biogenesis#GO:0071554;biosynthetic process#GO:0009058;cell wall macromolecule biosynthetic process#GO:0044038;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;glycosaminoglycan biosynthetic process#GO:0006024;peptidoglycan-based cell wall biogenesis#GO:0009273;peptidoglycan metabolic process#GO:0000270;metabolic process#GO:0008152;peptidoglycan biosynthetic process#GO:0009252;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan metabolic process#GO:0030203;cell wall biogenesis#GO:0042546;cell wall macromolecule metabolic process#GO:0044036;aminoglycan metabolic process#GO:0006022	cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;external encapsulating structure#GO:0030312;cell outer membrane#GO:0009279;membrane#GO:0016020;extracellular region#GO:0005576;outer membrane#GO:0019867		
ECOLI|EnsemblGenome=b0074|UniProtKB=P09151	P09151	leuA	PTHR10277:SF78	HOMOCITRATE SYNTHASE-RELATED	2-ISOPROPYLMALATE SYNTHASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746	branched-chain amino acid biosynthetic process#GO:0009082;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	transferase#PC00220	
ECOLI|EnsemblGenome=b2605|UniProtKB=P07021	P07021	yfiB	PTHR30329:SF17	STATOR ELEMENT OF FLAGELLAR MOTOR COMPLEX	LIPOPROTEIN YFIB-RELATED				structural protein#PC00211	
ECOLI|EnsemblGenome=b1227|UniProtKB=P11350	P11350	narI	PTHR30598:SF3	NITRATE REDUCTASE PRIVATE CHAPERONE, REDOX ENZYME MATURATION PROTEIN  REMP  FAMILY	RESPIRATORY NITRATE REDUCTASE 1 GAMMA CHAIN	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;nitrate metabolic process#GO:0042126;electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;anaerobic electron transport chain#GO:0019645;anaerobic respiration#GO:0009061	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;cell periphery#GO:0071944;membrane#GO:0016020;oxidoreductase complex#GO:1990204	chaperone#PC00072	
ECOLI|EnsemblGenome=b1072|UniProtKB=P75933	P75933	flgA	PTHR36307:SF2	FLAGELLA BASAL BODY P-RING FORMATION PROTEIN FLGA	FLAGELLA BASAL BODY P-RING FORMATION PROTEIN FLGA		archaeal or bacterial-type flagellum-dependent cell motility#GO:0097588;cilium or flagellum-dependent cell motility#GO:0001539;cellular process#GO:0009987;bacterial-type flagellum-dependent cell motility#GO:0071973;cell motility#GO:0048870		structural protein#PC00211	
ECOLI|EnsemblGenome=b0918|UniProtKB=P04951	P04951	kdsB	PTHR42866:SF13	3-DEOXY-MANNO-OCTULOSONATE CYTIDYLYLTRANSFERASE	3-DEOXY-MANNO-OCTULOSONATE CYTIDYLYLTRANSFERASE	transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740	carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;polysaccharide metabolic process#GO:0005976;small molecule metabolic process#GO:0044281;liposaccharide metabolic process#GO:1903509;lipopolysaccharide biosynthetic process#GO:0009103;carbohydrate metabolic process#GO:0005975;oxoacid metabolic process#GO:0043436;polysaccharide biosynthetic process#GO:0000271;lipopolysaccharide metabolic process#GO:0008653;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;lipid biosynthetic process#GO:0008610;carbohydrate biosynthetic process#GO:0016051;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	transferase#PC00220;nucleotidyltransferase#PC00174	
ECOLI|EnsemblGenome=b3320|UniProtKB=P60438	P60438	rplC	PTHR11229:SF16	50S RIBOSOMAL PROTEIN L3	LARGE RIBOSOMAL SUBUNIT PROTEIN UL3	structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198			ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b3197|UniProtKB=P45395	P45395	kdsD	PTHR42745:SF1	ARABINOSE 5-PHOSPHATE ISOMERASE KDSD	ARABINOSE 5-PHOSPHATE ISOMERASE KDSD					
ECOLI|EnsemblGenome=b1090|UniProtKB=P27247	P27247	plsX	PTHR30100:SF1	FATTY ACID/PHOSPHOLIPID SYNTHESIS PROTEIN PLSX	PHOSPHATE ACYLTRANSFERASE				transferase#PC00220	
ECOLI|EnsemblGenome=b2224|UniProtKB=P76461	P76461	atoB	PTHR18919:SF164	ACETYL-COA C-ACYLTRANSFERASE	ACETYL-COA ACETYLTRANSFERASE	catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747			transferase#PC00220;acyltransferase#PC00042	
ECOLI|EnsemblGenome=b4132|UniProtKB=P0AAE8	P0AAE8	cadB	PTHR42770:SF5	AMINO ACID TRANSPORTER-RELATED	CADAVERINE_LYSINE ANTIPORTER	active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;antiporter activity#GO:0015297;amino acid transmembrane transporter activity#GO:0015171		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	amino acid transporter#PC00046;secondary carrier transporter#PC00258;transporter#PC00227	
ECOLI|EnsemblGenome=b1867|UniProtKB=P0ADI7	P0ADI7	yecD	PTHR43540:SF7	PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED	ISOCHORISMATASE FAMILY PROTEIN YECD			cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	hydrolase#PC00121	
ECOLI|EnsemblGenome=b3986|UniProtKB=P0A7K2	P0A7K2	rplL	PTHR45987:SF28	39S RIBOSOMAL PROTEIN L12	LARGE RIBOSOMAL SUBUNIT PROTEIN BL12	RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;mRNA binding#GO:0003729	translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467	protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229	ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b4303|UniProtKB=P39364	P39364	sgcQ	PTHR21381:SF3	ZGC:162297	SGC REGION PROTEIN SGCQ-RELATED					
ECOLI|EnsemblGenome=b0720|UniProtKB=P0ABH7	P0ABH7	gltA	PTHR42871:SF1	CITRATE SYNTHASE	CITRATE SYNTHASE	catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746	tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;transferase#PC00220	Pyruvate metabolism#P02772>Citrate Synthetase#P03141;TCA cycle#P00051>Citrate Synthase#P01267
ECOLI|EnsemblGenome=b3210|UniProtKB=P0AEC3	P0AEC3	arcB	PTHR43719:SF27	TWO-COMPONENT HISTIDINE KINASE	AEROBIC RESPIRATION CONTROL SENSOR PROTEIN ARCB	catalytic activity#GO:0003824;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein histidine kinase activity#GO:0004673;catalytic activity, acting on a protein#GO:0140096;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;phosphorelay sensor kinase activity#GO:0000155;transferase activity#GO:0016740;kinase activity#GO:0016301;phosphoric ester hydrolase activity#GO:0042578;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672	phosphorelay signal transduction system#GO:0000160;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transmembrane signal receptor#PC00197;histidine kinase receptor of two-component system#PC00265	
ECOLI|EnsemblGenome=b2045|UniProtKB=P71242	P71242	wcaK	PTHR36836:SF1	COLANIC ACID BIOSYNTHESIS PROTEIN WCAK	COLANIC ACID BIOSYNTHESIS PROTEIN WCAK					
ECOLI|EnsemblGenome=b0364|UniProtKB=P71311	P71311	yaiS	PTHR12993:SF30	N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE-RELATED	N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE DEACETYLASE 1	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810			deacetylase#PC00087	
ECOLI|EnsemblGenome=b4085|UniProtKB=P32719	P32719	alsE	PTHR11749:SF3	RIBULOSE-5-PHOSPHATE-3-EPIMERASE	RIBULOSE-PHOSPHATE 3-EPIMERASE	metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;D-ribulose-phosphate 3-epimerase activity#GO:0004750;isomerase activity#GO:0016853;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854	phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;pentose-phosphate shunt, non-oxidative branch#GO:0009052;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt#GO:0006098;glyceraldehyde-3-phosphate metabolic process#GO:0019682;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;nucleotide metabolic process#GO:0009117;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing small molecule metabolic process#GO:0055086	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		Ascorbate degradation#P02729>L-xylulose-5-phosphate-3-epimerase#P02852
ECOLI|EnsemblGenome=b0409|UniProtKB=P0AG93	P0AG93	secF	PTHR30081:SF8	PROTEIN-EXPORT MEMBRANE PROTEIN SEC	PROTEIN TRANSLOCASE SUBUNIT SECF		macromolecule localization#GO:0033036;transport#GO:0006810;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b0527|UniProtKB=P45570	P45570	ybcI	PTHR35531:SF1	INNER MEMBRANE PROTEIN YBCI-RELATED	INNER MEMBRANE PROTEIN YBCI-RELATED			membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|EnsemblGenome=b2871|UniProtKB=P66899	P66899	ygeX	PTHR42937:SF1	FAMILY NOT NAMED	DIAMINOPROPIONATE AMMONIA-LYASE					
ECOLI|EnsemblGenome=b3687|UniProtKB=P0C054	P0C054	ibpA	PTHR47062:SF1	SMALL HEAT SHOCK PROTEIN IBPA	SMALL HEAT SHOCK PROTEIN IBPA			intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b3167|UniProtKB=P0A7G2	P0A7G2	rbfA	PTHR33515:SF2	RIBOSOME-BINDING FACTOR A, CHLOROPLASTIC-RELATED	30S RIBOSOME-BINDING FACTOR	ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488	ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b3071|UniProtKB=P64588	P64588	yqjI	PTHR43252:SF7	TRANSCRIPTIONAL REGULATOR YQJI	TRANSCRIPTIONAL REGULATOR YQJI	transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA binding#GO:0003677	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007		gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b2551|UniProtKB=P0A825	P0A825	glyA	PTHR11680:SF50	SERINE HYDROXYMETHYLTRANSFERASE	SERINE HYDROXYMETHYLTRANSFERASE	transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488	amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;oxoacid metabolic process#GO:0043436;tetrahydrofolate metabolic process#GO:0046653;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;methyltransferase#PC00155	Serine glycine biosynthesis#P02776>Glycine hydroxymethyltransferase#P03158
ECOLI|EnsemblGenome=b2096|UniProtKB=P0C8J6	P0C8J6	gatY	PTHR30304:SF12	D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE	D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE SUBUNIT GATY-RELATED	aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	lyase#PC00144;aldolase#PC00044	
ECOLI|EnsemblGenome=b2496|UniProtKB=P69931	P69931	hda	PTHR30050:SF5	CHROMOSOMAL REPLICATION INITIATOR PROTEIN DNAA	DNAA REGULATORY INACTIVATOR HDA	DNA replication origin binding#GO:0003688;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837	regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of DNA-templated DNA replication#GO:0090329;regulation of DNA metabolic process#GO:0051052;DNA replication#GO:0006260;regulation of DNA replication#GO:0006275;DNA-templated DNA replication#GO:0006261;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of DNA-templated DNA replication initiation#GO:0030174;negative regulation of DNA metabolic process#GO:0051053;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;negative regulation of DNA-templated DNA replication#GO:2000104;negative regulation of cellular process#GO:0048523;DNA replication initiation#GO:0006270	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b4212|UniProtKB=P0ACN2	P0ACN2	ytfH	PTHR33204:SF37	TRANSCRIPTIONAL REGULATOR, MARR FAMILY	HTH-TYPE TRANSCRIPTIONAL REGULATOR YODB	transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700	regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252	protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991	helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b2703|UniProtKB=P56580	P56580	srlE	PTHR39427:SF2	FAMILY NOT NAMED	PTS SYSTEM GLUCITOL_SORBITOL-SPECIFIC EIIB COMPONENT	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;active transmembrane transporter activity#GO:0022804;protein-phosphocysteine-sugar phosphotransferase activity#GO:0090563;carbohydrate transmembrane transporter activity#GO:0015144;phosphotransferase activity, alcohol group as acceptor#GO:0016773	carbohydrate transport#GO:0008643;transport#GO:0006810;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;cellular process#GO:0009987;import across plasma membrane#GO:0098739;carbohydrate transmembrane transport#GO:0034219	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b2951|UniProtKB=P67080	P67080	yggS	PTHR10146:SF14	PROLINE SYNTHETASE CO-TRANSCRIBED BACTERIAL HOMOLOG PROTEIN	PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEIN	ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;heterocyclic compound binding#GO:1901363		intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1285|UniProtKB=P77334	P77334	pdeR	PTHR44757:SF11	DIGUANYLATE CYCLASE DGCP	CYCLIC DI-GMP PHOSPHODIESTERASE PDER	phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788			cyclase#PC00079;lyase#PC00144	
ECOLI|EnsemblGenome=b1851|UniProtKB=P0ADF6	P0ADF6	edd	PTHR43661:SF1	D-XYLONATE DEHYDRATASE	PHOSPHOGLUCONATE DEHYDRATASE	catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835		cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	dehydratase#PC00091	
ECOLI|EnsemblGenome=b2094|UniProtKB=P69828	P69828	gatA	PTHR47738:SF4	PTS SYSTEM FRUCTOSE-LIKE EIIA COMPONENT-RELATED	PTS SYSTEM GALACTITOL-SPECIFIC EIIA COMPONENT	enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295				
ECOLI|EnsemblGenome=b0304|UniProtKB=P77212	P77212	rclA	PTHR43014:SF4	MERCURIC REDUCTASE	PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE RCLA-RELATED	binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;NAD(P)H dehydrogenase (quinone) activity#GO:0003955;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363			reductase#PC00198;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0274|UniProtKB=P0CF27	P0CF27	insB3	PTHR33293:SF1	INSERTION ELEMENT IS1 1 PROTEIN INSB-RELATED	INSERTION ELEMENT IS1 1 PROTEIN INSB-RELATED					
ECOLI|EnsemblGenome=b1997|UniProtKB=P0CF42	P0CF42	insC3	PTHR37936:SF3	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED	TRANSPOSASE INSC FOR INSERTION ELEMENT IS2A-RELATED				viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b0027|UniProtKB=P00804	P00804	lspA	PTHR33695:SF1	LIPOPROTEIN SIGNAL PEPTIDASE	LIPOPROTEIN SIGNAL PEPTIDASE	catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	aspartic protease#PC00053;protease#PC00190	
ECOLI|EnsemblGenome=b0603|UniProtKB=P77746	P77746	ybdO	PTHR30118:SF14	HTH-TYPE TRANSCRIPTIONAL REGULATOR LEUO-RELATED	LYSR FAMILY TRANSCRIPTIONAL REGULATOR	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789	protein-containing complex#GO:0032991;protein-DNA complex#GO:0032993	helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b3316|UniProtKB=P0A7U3	P0A7U3	rpsS	PTHR11880:SF8	RIBOSOMAL PROTEIN S19P FAMILY MEMBER	SMALL RIBOSOMAL SUBUNIT PROTEIN US19	structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198			ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b1670|UniProtKB=P77409	P77409	ydhU	PTHR30485:SF1	NI/FE-HYDROGENASE 1 B-TYPE CYTOCHROME SUBUNIT	CYTOCHROME YDHU-RELATED	binding#GO:0005488;heme binding#GO:0020037;tetrapyrrole binding#GO:0046906		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b3604|UniProtKB=P0ACL7	P0ACL7	lldR	PTHR43537:SF18	TRANSCRIPTIONAL REGULATOR, GNTR FAMILY	L-LACTATE DEHYDROGENASE OPERON REGULATORY PROTEIN-RELATED	transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468		gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b1053|UniProtKB=P25744	P25744	mdtG	PTHR43414:SF6	MULTIDRUG RESISTANCE PROTEIN MDTG	MULTIDRUG RESISTANCE PROTEIN MDTG					
ECOLI|EnsemblGenome=b0605|UniProtKB=P0AE08	P0AE08	ahpC	PTHR10681:SF121	THIOREDOXIN PEROXIDASE	ALKYL HYDROPEROXIDE REDUCTASE C	oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824	cellular process#GO:0009987;response to stress#GO:0006950;homeostatic process#GO:0042592;hydrogen peroxide metabolic process#GO:0042743;catabolic process#GO:0009056;response to stimulus#GO:0050896;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725;response to oxidative stress#GO:0006979	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829	peroxidase#PC00180;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3474|UniProtKB=P0AGM0	P0AGM0	yhhT	PTHR21716:SF21	TRANSMEMBRANE PROTEIN	TRANSPORT PROTEIN YHHT-RELATED		transport#GO:0006810;organic hydroxy compound transport#GO:0015850;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cell communication#GO:0007154;cellular process#GO:0009987;regulation of biological process#GO:0050789;response to biotic stimulus#GO:0009607;detection of stimulus#GO:0051606;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886		
ECOLI|Gene_OrderedLocusName=JW1451|UniProtKB=P24211	P24211	rhsE	PTHR32305:SF18	FAMILY NOT NAMED	PROTEIN RHSA-RELATED					
ECOLI|EnsemblGenome=b0807|UniProtKB=P75782	P75782	rlmF	PTHR13393:SF1	SAM-DEPENDENT METHYLTRANSFERASE	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE F				metabolite interconversion enzyme#PC00262;methyltransferase#PC00155;transferase#PC00220	
ECOLI|EnsemblGenome=b3515|UniProtKB=P63201	P63201	gadW	PTHR43280:SF33	ARAC-FAMILY TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR APPY-RELATED	transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468		helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b0738|UniProtKB=P0ABV6	P0ABV6	tolR	PTHR30558:SF7	EXBD MEMBRANE COMPONENT OF PMF-DRIVEN MACROMOLECULE IMPORT SYSTEM	TOL-PAL SYSTEM PROTEIN TOLR			cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b0426|UniProtKB=P0A8E7	P0A8E7	yajQ	PTHR30476:SF0	UPF0234 PROTEIN YAJQ	NUCLEOTIDE-BINDING PROTEIN YAJQ	nucleoside phosphate binding#GO:1901265;binding#GO:0005488;small molecule binding#GO:0036094;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		
ECOLI|EnsemblGenome=b2592|UniProtKB=P63284	P63284	clpB	PTHR11638:SF18	ATP-DEPENDENT CLP PROTEASE	AAA ATPASE DOMAIN-CONTAINING PROTEIN	ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824	response to temperature stimulus#GO:0009266;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;cellular response to heat#GO:0034605;response to heat#GO:0009408;cellular response to stress#GO:0033554	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	protein modifying enzyme#PC00260;protease#PC00190	
ECOLI|EnsemblGenome=b3899|UniProtKB=P32154	P32154	frvB	PTHR30505:SF0	FRUCTOSE-LIKE PERMEASE	FRUCTOSE-LIKE PTS SYSTEM EIIBC COMPONENT-RELATED	transferase activity#GO:0016740;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transferase activity, transferring phosphorus-containing groups#GO:0016772;active transmembrane transporter activity#GO:0022804;protein-phosphocysteine-sugar phosphotransferase activity#GO:0090563;phosphotransferase activity, alcohol group as acceptor#GO:0016773;carbohydrate transmembrane transporter activity#GO:0015144	transport#GO:0006810;carbohydrate transport#GO:0008643;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;import across plasma membrane#GO:0098739	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2887|UniProtKB=Q46820	Q46820	uacF	PTHR42783:SF3	GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN	GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN-RELATED	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824			oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2047|UniProtKB=P71241	P71241	wcaJ	PTHR30576:SF21	COLANIC BIOSYNTHESIS UDP-GLUCOSE LIPID CARRIER TRANSFERASE	UDP-GLUCOSE:UNDECAPRENYL-PHOSPHATE GLUCOSE-1-PHOSPHATE TRANSFERASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772	biosynthetic process#GO:0009058;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;metabolic process#GO:0008152	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	transferase#PC00220	
ECOLI|EnsemblGenome=b3326|UniProtKB=P45759	P45759	gspE	PTHR30258:SF27	TYPE II SECRETION SYSTEM PROTEIN GSPE-RELATED	BACTERIOPHAGE ADSORPTION PROTEIN B-RELATED	ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657	secretion by cell#GO:0032940;protein transport#GO:0015031;localization#GO:0051179;protein secretion#GO:0009306;transmembrane transport#GO:0055085;secretion#GO:0046903;protein localization to extracellular region#GO:0071692;export from cell#GO:0140352;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;protein secretion by the type II secretion system#GO:0015628;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;type II protein secretion system complex#GO:0015627	transporter#PC00227	
ECOLI|EnsemblGenome=b3843|UniProtKB=P0AAB4	P0AAB4	ubiD	PTHR30108:SF17	3-OCTAPRENYL-4-HYDROXYBENZOATE CARBOXY-LYASE-RELATED	3-OCTAPRENYL-4-HYDROXYBENZOATE CARBOXY-LYASE	carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829	biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;ubiquinone biosynthetic process#GO:0006744;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ketone metabolic process#GO:0042180;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	decarboxylase#PC00089	
ECOLI|EnsemblGenome=b4065|UniProtKB=P32703	P32703	yjcE	PTHR10110:SF86	SODIUM/HYDROGEN EXCHANGER	SODIUM_HYDROGEN EXCHANGER 7	metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324	intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;import into cell#GO:0098657;establishment of localization#GO:0051234;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	secondary carrier transporter#PC00258	
ECOLI|EnsemblGenome=b4377|UniProtKB=P39407	P39407	yjjU	PTHR14226:SF25	NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER	PHOSPHOESTERASE				esterase#PC00097;hydrolase#PC00121	
ECOLI|EnsemblGenome=b3163|UniProtKB=P0AFB1	P0AFB1	nlpI	PTHR12558:SF52	CELL DIVISION CYCLE 16,23,27	LIPOPROTEIN NLPI				ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260	
ECOLI|EnsemblGenome=b0036|UniProtKB=P31551	P31551	caiD	PTHR11941:SF54	ENOYL-COA HYDRATASE-RELATED	2,3-DEHYDROADIPYL-COA HYDRATASE-RELATED		cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;monocarboxylic acid catabolic process#GO:0072329;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440		hydratase#PC00120;lyase#PC00144;metabolite interconversion enzyme#PC00262	Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163
ECOLI|EnsemblGenome=b2963|UniProtKB=P0C066	P0C066	mltC	PTHR37423:SF2	SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE-RELATED	MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE C	peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824;carbon-oxygen lyase activity, acting on polysaccharides#GO:0016837;peptidoglycan lytic transglycosylase activity#GO:0008933;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829	cellular process#GO:0009987;cell division#GO:0051301	extracellular region#GO:0005576;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b0794|UniProtKB=P0A9U1	P0A9U1	ybhF	PTHR43038:SF3	ATP-BINDING CASSETTE, SUB-FAMILY H, MEMBER 1	ABC TRANSPORTER G FAMILY MEMBER 23 ISOFORM X1			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227;primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b2906|UniProtKB=P25535	P25535	ubiI	PTHR43876:SF27	UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL	2-OCTAPRENYLPHENOL HYDROXYLASE	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;oxidoreductase activity#GO:0016491	metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;ketone metabolic process#GO:0042180;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058		oxygenase#PC00177;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b4088|UniProtKB=P39265	P39265	alsB	PTHR46847:SF1	D-ALLOSE-BINDING PERIPLASMIC PROTEIN-RELATED	D-ALLOSE-BINDING PERIPLASMIC PROTEIN-RELATED	carbohydrate binding#GO:0030246;monosaccharide binding#GO:0048029;small molecule binding#GO:0036094;binding#GO:0005488	localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810	periplasmic space#GO:0042597;extracellular region#GO:0005576;outer membrane-bounded periplasmic space#GO:0030288;cellular anatomical structure#GO:0110165;cell envelope#GO:0030313		
ECOLI|EnsemblGenome=b3650|UniProtKB=P0AG24	P0AG24	spoT	PTHR21262:SF36	GUANOSINE-3',5'-BIS DIPHOSPHATE  3'-PYROPHOSPHOHYDROLASE	BIFUNCTIONAL (P)PPGPP SYNTHASE_HYDROLASE SPOT	transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;transferase activity#GO:0016740;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578	nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;response to stress#GO:0006950;response to nutrient levels#GO:0031667;organophosphate metabolic process#GO:0019637;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;nucleoside phosphate metabolic process#GO:0006753;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;response to starvation#GO:0042594		pyrophosphatase#PC00196;hydrolase#PC00121;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1746|UniProtKB=P76217	P76217	astD	PTHR11699:SF299	ALDEHYDE DEHYDROGENASE-RELATED	N-SUCCINYLGLUTAMATE 5-SEMIALDEHYDE DEHYDROGENASE	catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491	catabolic process#GO:0009056;cellular process#GO:0009987;amine catabolic process#GO:0009310;amine metabolic process#GO:0009308;metabolic process#GO:0008152		dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3125|UniProtKB=P0ABQ2	P0ABQ2	garR	PTHR43060:SF3	3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED	2-HYDROXY-3-OXOPROPIONATE REDUCTASE	oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281		dehydrogenase#PC00092;oxidoreductase#PC00176	Allantoin degradation#P02725>Tartronate semi-aldehyde dehydrogenase#P02823
ECOLI|EnsemblGenome=b1927|UniProtKB=P26612	P26612	amyA	PTHR43447:SF58	ALPHA-AMYLASE	CYTOPLASMIC ALPHA-AMYLASE	hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553			amylase#PC00048	
ECOLI|EnsemblGenome=b3770|UniProtKB=P0AB80	P0AB80	ilvE	PTHR42743:SF24	AMINO-ACID AMINOTRANSFERASE	BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE	transaminase activity#GO:0008483;catalytic activity#GO:0003824;transferase activity#GO:0016740	biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;aspartate family amino acid biosynthetic process#GO:0009067;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;proteinogenic amino acid biosynthetic process#GO:0170038;branched-chain amino acid biosynthetic process#GO:0009082;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	metabolite interconversion enzyme#PC00262;transaminase#PC00216;transferase#PC00220	Isoleucine biosynthesis#P02748>Branched chain amino acid aminotransferase#P02994;Valine biosynthesis#P02785>Branched chain amino acid aminotransferase#P03215;Alanine biosynthesis#P02724>Branched chain amino acid aminotransferase#P02815;Leucine biosynthesis#P02749>Branched chain amino acid aminotransferase#P03000
ECOLI|EnsemblGenome=b1168|UniProtKB=P75995	P75995	pdeG	PTHR33121:SF71	CYCLIC DI-GMP PHOSPHODIESTERASE PDEF	CYCLIC DI-GMP PHOSPHODIESTERASE PDEL-RELATED	hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788		membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121	
ECOLI|EnsemblGenome=b2845|UniProtKB=P63340	P63340	yqeG	PTHR35334:SF3	SERINE TRANSPORTER	INNER MEMBRANE TRANSPORT PROTEIN YQEG	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;amino acid transport#GO:0006865	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b1967|UniProtKB=P31658	P31658	hchA	PTHR48094:SF20	PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED	PROTEIN_NUCLEIC ACID DEGLYCASE 1	hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824	metabolic process#GO:0008152;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;aldehyde catabolic process#GO:0046185;response to chemical#GO:0042221;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;cellular response to chemical stimulus#GO:0070887;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;cellular response to stimulus#GO:0051716;cellular detoxification of aldehyde#GO:0110095;ketone metabolic process#GO:0042180	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b1004|UniProtKB=P0A8G6	P0A8G6	wrbA	PTHR30546:SF23	FLAVODOXIN-RELATED PROTEIN WRBA-RELATED	FLAVOPROTEIN-LIKE PROTEIN YCP4-RELATED	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;oxidoreductase activity, acting on NAD(P)H#GO:0016651;NAD(P)H dehydrogenase (quinone) activity#GO:0003955;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824		membrane#GO:0016020;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3118|UniProtKB=P0ACQ7	P0ACQ7	tdcA	PTHR30419:SF7	HTH-TYPE TRANSCRIPTIONAL REGULATOR YBHD	HTH-TYPE TRANSCRIPTIONAL REGULATOR TDCA	binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b2393|UniProtKB=P0AFF2	P0AFF2	nupC	PTHR10590:SF21	SODIUM/NUCLEOSIDE COTRANSPORTER	NUCLEOSIDE PERMEASE NUPC	solute:proton symporter activity#GO:0015295;symporter activity#GO:0015293;nucleobase-containing compound transmembrane transporter activity#GO:0015932;monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate derivative transmembrane transporter activity#GO:1901505;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;nucleoside transmembrane transporter activity#GO:0005337;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804	transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nitrogen compound transport#GO:0071705;nucleobase-containing compound transport#GO:0015931	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b3284|UniProtKB=P0A828	P0A828	smg	PTHR38692:SF1	PROTEIN SMG	PROTEIN SMG					
ECOLI|EnsemblGenome=b2526|UniProtKB=P0A6Z1	P0A6Z1	hscA	PTHR19375:SF176	HEAT SHOCK PROTEIN 70KDA	CHAPERONE PROTEIN HSCA	hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;protein binding#GO:0005515	protein refolding#GO:0042026;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238		Hsp70 family chaperone#PC00027;chaperone#PC00072	
ECOLI|EnsemblGenome=b0050|UniProtKB=P62672	P62672	apaG	PTHR14289:SF17	F-BOX ONLY PROTEIN 3	PROTEIN APAG	protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198	metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;translesion synthesis#GO:0019985;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA synthesis involved in DNA replication#GO:0090592;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896			
ECOLI|EnsemblGenome=b3389|UniProtKB=P07639	P07639	aroB	PTHR43622:SF7	3-DEHYDROQUINATE SYNTHASE	3-DEHYDROQUINATE SYNTHASE, CHLOROPLASTIC	catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835	small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;aromatic amino acid biosynthetic process#GO:0009073;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238		lyase#PC00144	Chorismate biosynthesis#P02734>3-Dehydroquinate synthase#P02872
ECOLI|EnsemblGenome=b0346|UniProtKB=P77569	P77569	mhpR	PTHR30136:SF23	HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY	DNA-BINDING TRANSCRIPTIONAL ACTIVATOR MHPR	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b0911|UniProtKB=P0AG67	P0AG67	rpsA	PTHR10724:SF14	30S RIBOSOMAL PROTEIN S1	SMALL RIBOSOMAL SUBUNIT PROTEIN BS1	nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;mRNA binding#GO:0003729;structural molecule activity#GO:0005198;RNA binding#GO:0003723	metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058	membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840	ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b4203|UniProtKB=P0A7R1	P0A7R1	rplI	PTHR21368:SF18	50S RIBOSOMAL PROTEIN L9	LARGE RIBOSOMAL SUBUNIT PROTEIN BL9	structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198	translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467		translational protein#PC00263;ribosomal protein#PC00202	
ECOLI|EnsemblGenome=b3529|UniProtKB=P37649	P37649	pdeK	PTHR33121:SF77	CYCLIC DI-GMP PHOSPHODIESTERASE PDEF	CYCLIC DI-GMP PHOSPHODIESTERASE PDEK-RELATED	hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578	regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	hydrolase#PC00121;phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2097|UniProtKB=P0A991	P0A991	fbaB	PTHR47916:SF4	FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 1	FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 1	carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;aldehyde-lyase activity#GO:0016832;fructose-bisphosphate aldolase activity#GO:0004332;lyase activity#GO:0016829			lyase#PC00144;aldolase#PC00044	
ECOLI|EnsemblGenome=b2543|UniProtKB=P0AD47	P0AD47	yphA	PTHR33452:SF1	OXIDOREDUCTASE CATD-RELATED	INNER MEMBRANE PROTEIN YPHA-RELATED			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b3158|UniProtKB=P45527	P45527	ubiU	PTHR30217:SF3	PEPTIDASE U32 FAMILY	UBIQUINONE BIOSYNTHESIS HYDROXYLASE UBIU		small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;ubiquinone biosynthetic process#GO:0006744;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283		protease#PC00190	
ECOLI|EnsemblGenome=b3266|UniProtKB=P24181	P24181	acrF	PTHR32063:SF72	SWARMING MOTILITY PROTEIN SWRC-RELATED	MULTIDRUG EXPORT PROTEIN ACRF					
ECOLI|EnsemblGenome=b3061|UniProtKB=P05847	P05847	ttdA	PTHR30389:SF17	FUMARATE HYDRATASE-RELATED	L(+)-TARTRATE DEHYDRATASE SUBUNIT ALPHA	catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836	tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;cellular process#GO:0009987;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	lyase#PC00144;hydratase#PC00120	
ECOLI|EnsemblGenome=b0829|UniProtKB=P75796	P75796	gsiA	PTHR43776:SF15	TRANSPORT ATP-BINDING PROTEIN	GLUTATHIONE IMPORT ATP-BINDING PROTEIN GSIA	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;tripeptide transmembrane transporter activity#GO:0042937;oligopeptide transmembrane transporter activity#GO:0035673		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b4264|UniProtKB=P39343	P39343	idnR	PTHR30146:SF37	LACI-RELATED TRANSCRIPTIONAL REPRESSOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR IDNR	DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794		Lambda repressor-like transcription factor#PC00245;DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b1399|UniProtKB=P76086	P76086	paaX	PTHR30319:SF1	PHENYLACETIC ACID REGULATOR-RELATED TRANSCRIPTIONAL REPRESSOR	TRANSCRIPTIONAL REPRESSOR PAAX		gene expression#GO:0010467;DNA-templated transcription#GO:0006351;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187		DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b2347|UniProtKB=P37327	P37327	yfdC	PTHR30520:SF2	FORMATE TRANSPORTER-RELATED	INNER MEMBRANE PROTEIN YFDC	secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;active transmembrane transporter activity#GO:0022804;nitrate transmembrane transporter activity#GO:0015112;monocarboxylic acid transmembrane transporter activity#GO:0008028	nitrogen compound transport#GO:0071705;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monocarboxylic acid transport#GO:0015718	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b1267|UniProtKB=P0AFR4	P0AFR4	yciO	PTHR42828:SF4	DHBP SYNTHASE RIBB-LIKE ALPHA/BETA DOMAIN-CONTAINING PROTEIN	THREONYLCARBAMOYL-AMP SYNTHASE YCIO			cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b2866|UniProtKB=Q46799	Q46799	xdhA	PTHR11908:SF132	XANTHINE DEHYDROGENASE	ALDEHYDE OXIDASE 1-RELATED	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491			oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3730|UniProtKB=P0ACC7	P0ACC7	glmU	PTHR43584:SF3	NUCLEOTIDYL TRANSFERASE	BIFUNCTIONAL PROTEIN GLMU	acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746	primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;nucleoside phosphate metabolic process#GO:0006753;UDP-N-acetylglucosamine biosynthetic process#GO:0006048;UDP-N-acetylglucosamine metabolic process#GO:0006047;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-sugar metabolic process#GO:0009225;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	transferase#PC00220;nucleotidyltransferase#PC00174	N-acetylglucosamine metabolism#P02756>Glucosamine-1-phosphate acetyltransferase#P03039;N-acetylglucosamine metabolism#P02756>N-acetylglucosamine-1-phosphate uridyltransferase#P03043;O-antigen biosynthesis#P02757>N-acetylglucosamine-1-phosphate uridyltransferase#P03052;Peptidoglycan biosynthesis#P02763>N-acetylglucosamine-1-phosphate uridyltransferase#P03086;O-antigen biosynthesis#P02757>Glucosamine-1-phosphate acetyltransferase#P03049
ECOLI|EnsemblGenome=b2844|UniProtKB=Q46939	Q46939	yqeF	PTHR18919:SF107	ACETYL-COA C-ACYLTRANSFERASE	ACETYL-COA ACETYLTRANSFERASE, CYTOSOLIC	catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747			acyltransferase#PC00042;transferase#PC00220	
ECOLI|EnsemblGenome=b0281|UniProtKB=P71298	P71298	intF	PTHR30629:SF6	PROPHAGE INTEGRASE	PROPHAGE INTEGRASE INTA-RELATED	catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097				
ECOLI|EnsemblGenome=b3155|UniProtKB=P45472	P45472	yhbQ	PTHR34477:SF1	UPF0213 PROTEIN YHBQ	UPF0213 PROTEIN YHBQ					
ECOLI|EnsemblGenome=b2098|UniProtKB=P76417	P76417	yegT	PTHR23522:SF4	BLL5896 PROTEIN	NUCLEOSIDE PERMEASE NUPG-RELATED	carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleoside transmembrane transporter activity#GO:0005337;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b1235|UniProtKB=P0AEV1	P0AEV1	rssB	PTHR48111:SF22	REGULATOR OF RPOS	REGULATOR OF RPOS	molecular transducer activity#GO:0060089;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165	helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b4124|UniProtKB=P0AD01	P0AD01	dcuR	PTHR45526:SF1	TRANSCRIPTIONAL REGULATORY PROTEIN DPIA	TRANSCRIPTIONAL REGULATORY PROTEIN DCUR-RELATED	molecular transducer activity#GO:0060089			DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b2627|UniProtKB=P52126	P52126	abpB	PTHR12131:SF1	ATP-DEPENDENT RNA AND DNA HELICASE	ANTI-BACTERIOPHAGE PROTEIN B				DNA metabolism protein#PC00009	
ECOLI|EnsemblGenome=b4294|UniProtKB=P19767	P19767	insA7	PTHR47923:SF1	INSERTION ELEMENT IS1 1 PROTEIN INSA-RELATED	INSERTION ELEMENT IS1 1 PROTEIN INSA-RELATED		macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA recombination#GO:0006310;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987			
ECOLI|EnsemblGenome=b1515|UniProtKB=P0AFS1	P0AFS1	lsrD	PTHR32196:SF71	ABC TRANSPORTER PERMEASE PROTEIN YPHD-RELATED-RELATED	AUTOINDUCER 2 IMPORT SYSTEM PERMEASE PROTEIN LSRD			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0404|UniProtKB=P21515	P21515	acpH	PTHR38764:SF1	ACYL CARRIER PROTEIN PHOSPHODIESTERASE	ACYL CARRIER PROTEIN PHOSPHODIESTERASE	hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824	lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283		hydrolase#PC00121;phosphodiesterase#PC00185	
ECOLI|EnsemblGenome=b2178|UniProtKB=P0AFU0	P0AFU0	yejB	PTHR30465:SF66	INNER MEMBRANE ABC TRANSPORTER	OLIGOPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN YEJB	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;nitrogen compound transport#GO:0071705	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b2975|UniProtKB=Q46839	Q46839	glcA	PTHR30003:SF0	L-LACTATE PERMEASE	GLYCOLATE PERMEASE GLCA-RELATED	active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:proton symporter activity#GO:0015295		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	transporter#PC00227	
ECOLI|EnsemblGenome=b4340|UniProtKB=P39389	P39389	yjiR	PTHR42790:SF7	AMINOTRANSFERASE	TRANSCRIPTIONAL REGULATOR-RELATED	catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483			transaminase#PC00216	
ECOLI|EnsemblGenome=b0532|UniProtKB=P77468	P77468	sfmD	PTHR30451:SF6	OUTER MEMBRANE USHER PROTEIN	OUTER MEMBRANE USHER PROTEIN SFMD	wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	cell adhesion#GO:0007155;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;membrane#GO:0016020;cell outer membrane#GO:0009279;external encapsulating structure#GO:0030312;outer membrane#GO:0019867;extracellular region#GO:0005576		
ECOLI|EnsemblGenome=b0900|UniProtKB=P75836	P75836	ycaN	PTHR30537:SF1	HTH-TYPE TRANSCRIPTIONAL REGULATOR	HTH-TYPE TRANSCRIPTIONAL REGULATOR PGRR	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090		helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b3198|UniProtKB=P0ABZ4	P0ABZ4	kdsC	PTHR21485:SF3	HAD SUPERFAMILY MEMBERS CMAS AND KDSC	N-ACYLNEURAMINATE CYTIDYLYLTRANSFERASE	nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772			nucleotidyltransferase#PC00174;transferase#PC00220	
ECOLI|EnsemblGenome=b1884|UniProtKB=P07364	P07364	cheR	PTHR24422:SF19	CHEMOTAXIS PROTEIN METHYLTRANSFERASE	CHEMOTAXIS PROTEIN METHYLTRANSFERASE	protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096	response to external stimulus#GO:0009605;locomotion#GO:0040011;response to chemical#GO:0042221;response to stimulus#GO:0050896;taxis#GO:0042330;chemotaxis#GO:0006935	protein-containing complex#GO:0032991	protein modifying enzyme#PC00260	
ECOLI|EnsemblGenome=b0026|UniProtKB=P00956	P00956	ileS	PTHR42765:SF1	SOLEUCYL-TRNA SYNTHETASE	ISOLEUCINE--TRNA LIGASE, CHLOROPLASTIC_MITOCHONDRIAL	catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640	translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263	
ECOLI|EnsemblGenome=b2340|UniProtKB=P76502	P76502	sixA	PTHR48100:SF78	BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED	PHOSPHOHISTIDINE PHOSPHATASE SIXA	hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788		cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	hydrolase#PC00121;phosphatase#PC00181	
ECOLI|EnsemblGenome=b2438|UniProtKB=P76540	P76540	eutK	PTHR33941:SF6	PROPANEDIOL UTILIZATION PROTEIN PDUA	BACTERIAL MICROCOMPARTMENT SHELL PROTEIN EUTK					
ECOLI|EnsemblGenome=b3432|UniProtKB=P07762	P07762	glgB	PTHR43651:SF14	1,4-ALPHA-GLUCAN-BRANCHING ENZYME	1,4-ALPHA-GLUCAN BRANCHING ENZYME GLGB	hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757	energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;glycogen biosynthetic process#GO:0005978;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glucan biosynthetic process#GO:0009250;polysaccharide biosynthetic process#GO:0000271;energy reserve metabolic process#GO:0006112;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977	cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	amylase#PC00048	
ECOLI|EnsemblGenome=b3825|UniProtKB=P07000	P07000	pldB	PTHR11614:SF186	PHOSPHOLIPASE-RELATED	LYSOPHOSPHOLIPASE L2	hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;phosphatidylcholine lysophospholipase A1 activity#GO:0004622		membrane#GO:0016020;cellular anatomical structure#GO:0110165	lipase#PC00143;phospholipase#PC00186	
ECOLI|Gene_OrderedLocusName=b4496|UniProtKB=P76335	P76335	yedS	PTHR34501:SF8	PROTEIN YDDL-RELATED	OUTER MEMBRANE PORIN N-RELATED	passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;wide pore channel activity#GO:0022829;channel activity#GO:0015267		protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane#GO:0016020		
ECOLI|EnsemblGenome=b2945|UniProtKB=P25736	P25736	endA	PTHR33607:SF2	ENDONUCLEASE-1	ENDONUCLEASE-1	catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;nuclease activity#GO:0004518	catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;DNA catabolic process#GO:0006308;metabolic process#GO:0008152			
ECOLI|EnsemblGenome=b0530|UniProtKB=P0ABW5	P0ABW5	sfmA	PTHR33420:SF12	FIMBRIAL SUBUNIT ELFA-RELATED	FIMBRIN-LIKE PROTEIN FIMI-RELATED		cell-substrate adhesion#GO:0031589;cell adhesion#GO:0007155;cellular process#GO:0009987;single-species biofilm formation#GO:0044010	cellular anatomical structure#GO:0110165;cell projection#GO:0042995		
ECOLI|EnsemblGenome=b0801|UniProtKB=P30178	P30178	hcxB	PTHR11091:SF0	OXIDOREDUCTASE-RELATED	MALATE DEHYDROGENASE				oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	Allantoin degradation#P02725>Ureidoglycolate dehydrogenase#P02820;TCA cycle#P00051>Malate Dehydrogenase#P01270;Pyruvate metabolism#P02772>Malate Dehydrogenase#P03138
ECOLI|EnsemblGenome=b0333|UniProtKB=P31660	P31660	prpC	PTHR11739:SF25	CITRATE SYNTHASE	2-METHYLCITRATE SYNTHASE	acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824	generation of precursor metabolites and energy#GO:0006091;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;energy derivation by oxidation of organic compounds#GO:0015980;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;aerobic respiration#GO:0009060;fatty acid catabolic process#GO:0009062;short-chain fatty acid catabolic process#GO:0019626;cellular respiration#GO:0045333;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056	membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974	transferase#PC00220;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3668|UniProtKB=P09835	P09835	uhpB	PTHR24421:SF58	NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED	SIGNAL TRANSDUCTION HISTIDINE-PROTEIN KINASE_PHOSPHATASE UHPB	phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;phosphorelay sensor kinase activity#GO:0000155;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, nitrogenous group as acceptor#GO:0016775;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein histidine kinase activity#GO:0004673;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772	cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944		
ECOLI|EnsemblGenome=b0465|UniProtKB=P77338	P77338	mscK	PTHR30347:SF10	POTASSIUM CHANNEL RELATED	MECHANOSENSITIVE CHANNEL MSCK	channel activity#GO:0015267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;gated channel activity#GO:0022836;passive transmembrane transporter activity#GO:0022803	regulation of cellular component size#GO:0032535;cellular process#GO:0009987;cellular component organization#GO:0016043;homeostatic process#GO:0042592;biological regulation#GO:0065007;chemical homeostasis#GO:0048878;regulation of anatomical structure size#GO:0090066;intracellular chemical homeostasis#GO:0055082;regulation of cell size#GO:0008361;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725;cellular component organization or biogenesis#GO:0071840	cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	ion channel#PC00133	
ECOLI|EnsemblGenome=b3411|UniProtKB=P31667	P31667	rpnA	PTHR34611:SF5	INACTIVE RECOMBINATION-PROMOTING NUCLEASE-LIKE PROTEIN RPNE	RECOMBINATION-PROMOTING NUCLEASE RPNA-RELATED	DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520	primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170			
ECOLI|EnsemblGenome=b3530|UniProtKB=P37650	P37650	bcsC	PTHR44943:SF13	CELLULOSE SYNTHASE OPERON PROTEIN C	CELLULOSE SYNTHASE OPERON PROTEIN C					
ECOLI|EnsemblGenome=b2040|UniProtKB=P37760	P37760	rfbD	PTHR10491:SF4	DTDP-4-DEHYDRORHAMNOSE REDUCTASE	DTDP-4-DEHYDRORHAMNOSE REDUCTASE				reductase#PC00198	O-antigen biosynthesis#P02757>dTDP-4-dehydrorhamnose reductase#P03050
ECOLI|EnsemblGenome=b4161|UniProtKB=P39286	P39286	rsgA	PTHR32120:SF11	SMALL RIBOSOMAL SUBUNIT BIOGENESIS GTPASE RSGA	SMALL RIBOSOMAL SUBUNIT BIOGENESIS GTPASE RSGA 1, MITOCHONDRIAL-RELATED	GTPase activity#GO:0003924;binding#GO:0005488;nucleic acid binding#GO:0003676;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;RNA binding#GO:0003723;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;rRNA binding#GO:0019843;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111	ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-RNA complex assembly#GO:0022618;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;ribosome biogenesis#GO:0042254;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;ribosomal small subunit assembly#GO:0000028;ribosomal small subunit biogenesis#GO:0042274		RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b4160|UniProtKB=P0A8K1	P0A8K1	psd	PTHR10067:SF22	PHOSPHATIDYLSERINE DECARBOXYLASE	PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME	catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829	lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650		decarboxylase#PC00089;lyase#PC00144;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0939|UniProtKB=P75856	P75856	elfD	PTHR30251:SF0	PILUS ASSEMBLY CHAPERONE	FIMBRIAL CHAPERONE PROTEIN ELFD-RELATED		protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152	cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288;extracellular region#GO:0005576;periplasmic space#GO:0042597	chaperone#PC00072	
ECOLI|EnsemblGenome=b1289|UniProtKB=P45736	P45736	ycjD	PTHR38590:SF1	BLL0828 PROTEIN	DUF559, PUTATIVE-RELATED					
ECOLI|EnsemblGenome=b1363|UniProtKB=P23849	P23849	trkG	PTHR32024:SF2	TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKG-RELATED	TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKG-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;potassium ion transmembrane transporter activity#GO:0015079;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324	potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020		
ECOLI|EnsemblGenome=b3933|UniProtKB=P29131	P29131	ftsN	PTHR38687:SF2	CELL DIVISION PROTEIN DEDD-RELATED	CELL DIVISION PROTEIN FTSN		cellular component organization or biogenesis#GO:0071840;division septum assembly#GO:0000917;cytokinesis#GO:0000910;cytokinetic process#GO:0032506;cellular component assembly#GO:0022607;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell septum assembly#GO:0090529;cellular component biogenesis#GO:0044085;cell cycle process#GO:0022402;cell division#GO:0051301;cellular process#GO:0009987	cell septum#GO:0030428;division septum#GO:0000935;cellular anatomical structure#GO:0110165;cell division site#GO:0032153		
ECOLI|EnsemblGenome=b3787|UniProtKB=P27829	P27829	wecC	PTHR43491:SF1	UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE	UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824	polysaccharide metabolic process#GO:0005976;carbohydrate biosynthetic process#GO:0016051;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;polysaccharide biosynthetic process#GO:0000271		dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	Mannose metabolism#P02752>GDP Mannose 6-dehydrogenase#P03021
ECOLI|EnsemblGenome=b3775|UniProtKB=P0A9L5	P0A9L5	ppiC	PTHR43629:SF3	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE C	catalytic activity#GO:0003824;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;cis-trans isomerase activity#GO:0016859;catalytic activity, acting on a protein#GO:0140096			chaperone#PC00072	
ECOLI|EnsemblGenome=b0102|UniProtKB=P36680	P36680	zapD	PTHR39455:SF1	CELL DIVISION PROTEIN ZAPD	CELL DIVISION PROTEIN ZAPD		cell cycle process#GO:0022402;cell division#GO:0051301;cellular process#GO:0009987;cell cycle#GO:0007049;reproductive process#GO:0022414;reproductive process in single-celled organism#GO:0022413;cytokinesis#GO:0000910;FtsZ-dependent cytokinesis#GO:0043093	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cell division site#GO:0032153;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b2523|UniProtKB=P37095	P37095	pepB	PTHR11963:SF20	LEUCINE AMINOPEPTIDASE-RELATED	PEPTIDASE B	hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824	proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	metalloprotease#PC00153;protease#PC00190	
ECOLI|EnsemblGenome=b2166|UniProtKB=P30235	P30235	psuK	PTHR43085:SF1	HEXOKINASE FAMILY MEMBER	L-GLYCERO-L-GALACTO-OCTULURONATE KINASE-RELATED	kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824			carbohydrate kinase#PC00065;metabolite interconversion enzyme#PC00262;transferase#PC00220	
ECOLI|EnsemblGenome=b2091|UniProtKB=P0A9S3	P0A9S3	gatD	PTHR43161:SF26	SORBITOL DEHYDROGENASE	GALACTITOL 1-PHOSPHATE 5-DEHYDROGENASE				oxidoreductase#PC00176;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b3719|UniProtKB=P31471	P31471	yieL	PTHR48098:SF1	ENTEROCHELIN ESTERASE-RELATED	DIACYLGLYCEROL ACYLTRANSFERASE_MYCOLYLTRANSFERASE AG85B	acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740			hydrolase#PC00121;esterase#PC00097;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b4063|UniProtKB=P0ACS2	P0ACS2	soxR	PTHR30204:SF0	REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR	REDOX-SENSITIVE TRANSCRIPTIONAL ACTIVATOR SOXR	DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110	regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789		gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b1781|UniProtKB=P76234	P76234	yeaE	PTHR43638:SF3	OXIDOREDUCTASE, ALDO/KETO REDUCTASE FAMILY PROTEIN	METHYLGLYOXAL REDUCTASE YEAE	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824			oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2784|UniProtKB=P0AG20	P0AG20	relA	PTHR21262:SF31	GUANOSINE-3',5'-BIS DIPHOSPHATE  3'-PYROPHOSPHOHYDROLASE	GTP DIPHOSPHOKINASE RSH3, CHLOROPLASTIC-RELATED				metabolite interconversion enzyme#PC00262;pyrophosphatase#PC00196;hydrolase#PC00121	
ECOLI|EnsemblGenome=b2955|UniProtKB=P52062	P52062	hemW	PTHR13932:SF5	COPROPORPHYRINIGEN III OXIDASE	RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL	iron-sulfur cluster binding#GO:0051536;binding#GO:0005488;small molecule binding#GO:0036094	tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;porphyrin-containing compound metabolic process#GO:0006778;cellular process#GO:0009987;porphyrin-containing compound biosynthetic process#GO:0006779;tetrapyrrole biosynthetic process#GO:0033014;biosynthetic process#GO:0009058	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	oxidase#PC00175	Heme biosynthesis#P02746>Coproporphyrinogen oxidase (oxygen independent)#P02970
ECOLI|EnsemblGenome=b0766|UniProtKB=P21829	P21829	ybhA	PTHR10000:SF8	PHOSPHOSERINE PHOSPHATASE	HAD SUPERFAMILY HYDROLASE-LIKE, TYPE 3	phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;magnesium ion binding#GO:0000287;cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167		cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	protein phosphatase#PC00195	
ECOLI|EnsemblGenome=b2664|UniProtKB=P37338	P37338	glaR	PTHR43537:SF20	TRANSCRIPTIONAL REGULATOR, GNTR FAMILY	HTH-TYPE TRANSCRIPTIONAL REPRESSOR GLAR	DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565	regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141		helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b0800|UniProtKB=P30177	P30177	ybiB	PTHR43285:SF4	ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE	DNA-BINDING PROTEIN YBIB		proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;amine metabolic process#GO:0009308;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;indole-containing compound metabolic process#GO:0042430;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;aromatic amino acid biosynthetic process#GO:0009073	cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829	transferase#PC00220;glycosyltransferase#PC00111	
ECOLI|EnsemblGenome=b4031|UniProtKB=P0AGF4	P0AGF4	xylE	PTHR48020:SF12	PROTON MYO-INOSITOL COTRANSPORTER	METABOLITE TRANSPORT PROTEIN YFL040W-RELATED	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215	establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987	cellular anatomical structure#GO:0110165;membrane#GO:0016020	transporter#PC00227	
ECOLI|EnsemblGenome=b3543|UniProtKB=P0AEF8	P0AEF8	dppB	PTHR43163:SF10	DIPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN DPPB-RELATED	DIPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN DPPB-RELATED	oligopeptide transmembrane transporter activity#GO:0035673;dipeptide transmembrane transporter activity#GO:0071916;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	transporter#PC00227	
ECOLI|EnsemblGenome=b1513|UniProtKB=P77257	P77257	lsrA	PTHR43790:SF2	CARBOHYDRATE TRANSPORT ATP-BINDING PROTEIN MG119-RELATED	AUTOINDUCER 2 IMPORT ATP-BINDING PROTEIN LSRA	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215		cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b3232|UniProtKB=P64612	P64612	zapE	PTHR12169:SF34	ATPASE N2B	CELL DIVISION PROTEIN ZAPE	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111	cellular process#GO:0009987;cell division#GO:0051301	cellular anatomical structure#GO:0110165;cell division site#GO:0032153;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737		
ECOLI|EnsemblGenome=b3680|UniProtKB=P31449	P31449	yidL	PTHR43280:SF31	ARAC-FAMILY TRANSCRIPTIONAL REGULATOR	ARAC FAMILY REGULATORY PROTEIN	sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976	regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090		DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116	
ECOLI|EnsemblGenome=b2761|UniProtKB=P38036	P38036	ygcB	PTHR47963:SF9	DEAD-BOX ATP-DEPENDENT RNA HELICASE 47, MITOCHONDRIAL	CRISPR-ASSOCIATED ENDONUCLEASE_HELICASE CAS3	macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723			RNA helicase#PC00032;RNA metabolism protein#PC00031	
ECOLI|EnsemblGenome=b2944|UniProtKB=P39902	P39902	sprT	PTHR38773:SF1	PROTEIN SPRT	PROTEIN SPRT					
ECOLI|EnsemblGenome=b0492|UniProtKB=P77395	P77395	cnoX	PTHR43601:SF3	THIOREDOXIN, MITOCHONDRIAL	THIOREDOXIN M3, CHLOROPLASTIC		cellular homeostasis#GO:0019725;homeostatic process#GO:0042592;cell redox homeostasis#GO:0045454		oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b1333|UniProtKB=P0AAC0	P0AAC0	uspE	PTHR47892:SF1	UNIVERSAL STRESS PROTEIN E	UNIVERSAL STRESS PROTEIN E					
ECOLI|EnsemblGenome=b1646|UniProtKB=P0AGD1	P0AGD1	sodC	PTHR10003:SF97	SUPEROXIDE DISMUTASE  CU-ZN -RELATED	SUPEROXIDE DISMUTASE [CU-ZN]	cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;oxidoreductase activity#GO:0016491;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;copper ion binding#GO:0005507	cellular oxidant detoxification#GO:0098869;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to stress#GO:0006950;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;response to reactive oxygen species#GO:0000302;cellular response to chemical stress#GO:0062197;superoxide metabolic process#GO:0006801;response to oxidative stress#GO:0006979;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;cellular response to chemical stimulus#GO:0070887	extracellular region#GO:0005576;periplasmic space#GO:0042597;cellular anatomical structure#GO:0110165	oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b1388|UniProtKB=P76077	P76077	paaA	PTHR30458:SF2	PHENYLACETIC ACID DEGRADATION PROTEIN PAA	1,2-PHENYLACETYL-COA EPOXIDASE, SUBUNIT A		catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular response to stimulus#GO:0051716;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;response to chemical#GO:0042221;cellular response to xenobiotic stimulus#GO:0071466;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152	oxidoreductase complex#GO:1990204;cytosol#GO:0005829;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b4017|UniProtKB=P23325	P23325	arpA	PTHR24121:SF23	NO MECHANORECEPTOR POTENTIAL C, ISOFORM D-RELATED	ANKYRIN REPEAT PROTEIN A					
ECOLI|EnsemblGenome=b3670|UniProtKB=P0ADF8	P0ADF8	ilvN	PTHR30239:SF4	ACETOLACTATE SYNTHASE SMALL SUBUNIT	ACETOLACTATE SYNTHASE ISOZYME 1 SMALL SUBUNIT	transketolase or transaldolase activity#GO:0016744;catalytic activity#GO:0003824;transferase activity#GO:0016740	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;branched-chain amino acid biosynthetic process#GO:0009082;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	transferase#PC00220	
ECOLI|EnsemblGenome=b0516|UniProtKB=P77425	P77425	allC	PTHR32494:SF5	ALLANTOATE DEIMINASE-RELATED	ALLANTOATE AMIDOHYDROLASE	hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824	metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056			
ECOLI|EnsemblGenome=b2306|UniProtKB=P07109	P07109	hisP	PTHR43166:SF15	AMINO ACID IMPORT ATP-BINDING PROTEIN	HISTIDINE_LYSINE_ARGININE_ORNITHINE TRANSPORT ATP-BINDING PROTEIN HISP	primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215		plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b1116|UniProtKB=P0ADC3	P0ADC3	lolC	PTHR30489:SF8	LIPOPROTEIN-RELEASING SYSTEM TRANSMEMBRANE PROTEIN LOLE	LIPOPROTEIN-RELEASING SYSTEM TRANSMEMBRANE PROTEIN LOLC		cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;localization within membrane#GO:0051668;macromolecule localization#GO:0033036	plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020		
ECOLI|EnsemblGenome=b0258|UniProtKB=Q47688	Q47688	ykfC	PTHR34047:SF8	NUCLEAR INTRON MATURASE 1, MITOCHONDRIAL-RELATED	PROTEIN YKFC					
ECOLI|EnsemblGenome=b1097|UniProtKB=P28306	P28306	mltG	PTHR30518:SF2	ENDOLYTIC MUREIN TRANSGLYCOSYLASE	ENDOLYTIC MUREIN TRANSGLYCOSYLASE					
ECOLI|EnsemblGenome=b1286|UniProtKB=P30850	P30850	rnb	PTHR23355:SF37	RIBONUCLEASE	EXORIBONUCLEASE 2		RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556	cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	exoribonuclease#PC00099	
ECOLI|EnsemblGenome=b0765|UniProtKB=P09833	P09833	modC	PTHR43514:SF4	ABC TRANSPORTER I FAMILY MEMBER 10	MOLYBDENUM IMPORT ATP-BINDING PROTEIN MODC				ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227	
ECOLI|EnsemblGenome=b2753|UniProtKB=P10423	P10423	iap	PTHR12147:SF59	METALLOPEPTIDASE M28 FAMILY MEMBER	ALKALINE PHOSPHATASE ISOZYME CONVERSION PROTEIN		primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170		metalloprotease#PC00153;protease#PC00190	
ECOLI|EnsemblGenome=b1202|UniProtKB=P76017	P76017	ycgV	PTHR12338:SF5	AUTOTRANSPORTER	ANTIGEN 43-RELATED				protease#PC00190	
ECOLI|EnsemblGenome=b2368|UniProtKB=P52599	P52599	emrK	PTHR30386:SF19	MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP	MULTIDRUG EXPORT PROTEIN EMRA-RELATED	carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;bile acid transmembrane transporter activity#GO:0015125	export from cell#GO:0140352;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;organic hydroxy compound transport#GO:0015850;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;transmembrane transport#GO:0055085;bile acid and bile salt transport#GO:0015721;lipid localization#GO:0010876;detoxification#GO:0098754;lipid transport#GO:0006869;response to chemical#GO:0042221;xenobiotic detoxification by transmembrane export across the plasma membrane#GO:1990961;cellular process#GO:0009987;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;xenobiotic transport#GO:0042908	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	transporter#PC00227	
ECOLI|EnsemblGenome=b4483|UniProtKB=P27859	P27859	tatD	PTHR10060:SF48	TATD FAMILY DEOXYRIBONUCLEASE	DEOXYRIBONUCLEASE TATDN1				DNA metabolism protein#PC00009;endodeoxyribonuclease#PC00093	
ECOLI|EnsemblGenome=b3368|UniProtKB=P0AEA8	P0AEA8	cysG	PTHR45790:SF1	SIROHEME SYNTHASE-RELATED	SIROHEME SYNTHASE	S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;catalytic activity#GO:0003824;transferase activity#GO:0016740	cellular process#GO:0009987;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;heme metabolic process#GO:0042168;biosynthetic process#GO:0009058;tetrapyrrole biosynthetic process#GO:0033014;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;porphyrin-containing compound biosynthetic process#GO:0006779		methyltransferase#PC00155	
ECOLI|EnsemblGenome=b4177|UniProtKB=P0A7D4	P0A7D4	purA	PTHR11846:SF0	ADENYLOSUCCINATE SYNTHETASE	ADENYLOSUCCINATE SYNTHETASE	catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879	organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;IMP metabolic process#GO:0046040;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;ligase#PC00142	Wnt signaling pathway#P00057>NFAT Target Genes#G01559;De novo purine biosynthesis#P02738>Adenylosuccinate synthase#P02890
ECOLI|EnsemblGenome=b4175|UniProtKB=P0ABC3	P0ABC3	hflC	PTHR42911:SF1	MODULATOR OF FTSH PROTEASE HFLC	MODULATOR OF FTSH PROTEASE HFLC			cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991		
ECOLI|EnsemblGenome=b2381|UniProtKB=P0AE39	P0AE39	ypdB	PTHR48111:SF17	REGULATOR OF RPOS	TRANSCRIPTIONAL REGULATORY PROTEIN YPDB	double-stranded DNA binding#GO:0003690;molecular transducer activity#GO:0060089;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837	regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468	cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b1514|UniProtKB=P77672	P77672	lsrC	PTHR32196:SF29	ABC TRANSPORTER PERMEASE PROTEIN YPHD-RELATED-RELATED	AUTOINDUCER 2 IMPORT SYSTEM PERMEASE PROTEIN LSRC			plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020	ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068	
ECOLI|EnsemblGenome=b0422|UniProtKB=P0A8G9	P0A8G9	xseB	PTHR34137:SF1	EXODEOXYRIBONUCLEASE 7 SMALL SUBUNIT	EXODEOXYRIBONUCLEASE 7 SMALL SUBUNIT	catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;DNA exonuclease activity#GO:0004529;hydrolase activity#GO:0016787;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;exonuclease activity#GO:0004527		cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829	exodeoxyribonuclease#PC00098	
ECOLI|EnsemblGenome=b3235|UniProtKB=P0AEE3	P0AEE3	degS	PTHR43019:SF62	SERINE ENDOPROTEASE DEGS	SERINE ENDOPROTEASE DEGS				protein modifying enzyme#PC00260;serine protease#PC00203	
ECOLI|EnsemblGenome=b0906|UniProtKB=P75839	P75839	ycaP	PTHR34582:SF6	UPF0702 TRANSMEMBRANE PROTEIN YCAP	UPF0702 TRANSMEMBRANE PROTEIN YCAP					
ECOLI|Gene_OrderedLocusName=b0553|UniProtKB=P21420	P21420	nmpC	PTHR34501:SF2	PROTEIN YDDL-RELATED	OUTER MEMBRANE PORIN F-RELATED	channel activity#GO:0015267;wide pore channel activity#GO:0022829;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803		membrane protein complex#GO:0098796;membrane#GO:0016020;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b2839|UniProtKB=P03030	P03030	lysR	PTHR30427:SF1	TRANSCRIPTIONAL ACTIVATOR PROTEIN LYSR	TRANSCRIPTIONAL ACTIVATOR PROTEIN LYSR	DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488	positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;positive regulation of macromolecule metabolic process#GO:0010604;regulation of cellular process#GO:0050794		DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264	
ECOLI|EnsemblGenome=b4219|UniProtKB=P0A744	P0A744	msrA	PTHR42799:SF2	MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE	MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE	catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491	response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165	metabolite interconversion enzyme#PC00262;reductase#PC00198	
ECOLI|EnsemblGenome=b2298|UniProtKB=P39263	P39263	yfcC	PTHR43652:SF2	BASIC AMINO ACID ANTIPORTER YFCC-RELATED	BASIC AMINO ACID ANTIPORTER YFCC-RELATED			cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944	primary active transporter#PC00068;transporter#PC00227	
ECOLI|EnsemblGenome=b1894|UniProtKB=P0CF11	P0CF11	insA5	PTHR47923:SF1	INSERTION ELEMENT IS1 1 PROTEIN INSA-RELATED	INSERTION ELEMENT IS1 1 PROTEIN INSA-RELATED		macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA recombination#GO:0006310;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987			
ECOLI|EnsemblGenome=b1850|UniProtKB=P0A955	P0A955	eda	PTHR30246:SF2	2-KETO-3-DEOXY-6-PHOSPHOGLUCONATE ALDOLASE	KHG_KDPG ALDOLASE	catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832			aldolase#PC00044;lyase#PC00144	
ECOLI|EnsemblGenome=b3213|UniProtKB=P09832	P09832	gltD	PTHR42783:SF3	GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN	GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN-RELATED	oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824			metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176	
ECOLI|EnsemblGenome=b0441|UniProtKB=P0ADY1	P0ADY1	ppiD	PTHR47529:SF1	PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D	PERIPLASMIC CHAPERONE PPID		protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152		chaperone#PC00072	
ECOLI|EnsemblGenome=b1552|UniProtKB=P0A986	P0A986	cspI	PTHR11544:SF138	COLD SHOCK DOMAIN CONTAINING PROTEINS	COLD SHOCK PROTEIN CSPA-RELATED					
ECOLI|EnsemblGenome=b4120|UniProtKB=P02921	P02921	melB	PTHR11328:SF36	MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN	MELIBIOSE PERMEASE		cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179	membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886	primary active transporter#PC00068	
ECOLI|EnsemblGenome=b1084|UniProtKB=P21513	P21513	rne	PTHR30001:SF1	RIBONUCLEASE	RIBONUCLEASE E_G-LIKE PROTEIN, CHLOROPLASTIC	catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;catalytic activity, acting on RNA#GO:0140098	primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170	cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	RNA metabolism protein#PC00031;endoribonuclease#PC00094	
ECOLI|EnsemblGenome=b4239|UniProtKB=P28904	P28904	treC	PTHR10357:SF239	ALPHA-GLUCOSIDASE FAMILY MEMBER	TREHALOSE-6-PHOSPHATE HYDROLASE	hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824	metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052;oligosaccharide metabolic process#GO:0009311;primary metabolic process#GO:0044238;cellular process#GO:0009987;oligosaccharide catabolic process#GO:0009313;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975		amylase#PC00048;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3893|UniProtKB=P0AAJ5	P0AAJ5	fdoH	PTHR43545:SF7	FORMATE DEHYDROGENASE, NITRATE-INDUCIBLE, IRON-SULFUR SUBUNIT	FORMATE DEHYDROGENASE-O IRON-SULFUR SUBUNIT	catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491	monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;anaerobic respiration#GO:0009061;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980	catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991	oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b2143|UniProtKB=P0ABF6	P0ABF6	cdd	PTHR11644:SF2	CYTIDINE DEAMINASE	CYTIDINE DEAMINASE	catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239	catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;nucleobase-containing small molecule catabolic process#GO:0034656;primary metabolic process#GO:0044238;nucleoside catabolic process#GO:0009164;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule biosynthetic process#GO:0044283	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737	deaminase#PC00088	Pyrimidine Metabolism#P02771>Cytidine Deaminase#P03130;Salvage pyrimidine ribonucleotides#P02775>Cytidine deaminase#P03154;Salvage pyrimidine deoxyribonucleotides#P02774>Cytidine deaminase#P03144
ECOLI|EnsemblGenome=b4397|UniProtKB=P0AE91	P0AE91	creA	PTHR37952:SF2	FAMILY NOT NAMED	PROTEIN CREA			cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		
ECOLI|EnsemblGenome=b4005|UniProtKB=P15640	P15640	purD	PTHR43472:SF1	PHOSPHORIBOSYLAMINE--GLYCINE LIGASE	PHOSPHORIBOSYLAMINE--GLYCINE LIGASE, CHLOROPLASTIC	ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874			ligase#PC00142	De novo purine biosynthesis#P02738>Phosphoribosylamine glycine ligase#P02908
ECOLI|EnsemblGenome=b2525|UniProtKB=P0A9R4	P0A9R4	fdx	PTHR23426:SF80	FERREDOXIN/ADRENODOXIN	2FE-2S FERREDOXIN		metabolic process#GO:0008152;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622	oxidoreductase#PC00176	Vitamin D metabolism and pathway#P04396>FDX#P04607
ECOLI|EnsemblGenome=b1140|UniProtKB=P75969	P75969	intE	PTHR30349:SF99	PHAGE INTEGRASE-RELATED	PROPHAGE INTEGRASE INTD-RELATED	catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097	nucleobase-containing compound metabolic process#GO:0006139;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle process#GO:0022402;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;chromosome segregation#GO:0007059		viral or transposable element protein#PC00237	
ECOLI|EnsemblGenome=b0021|UniProtKB=P0CF25	P0CF25	insB1	PTHR33293:SF1	INSERTION ELEMENT IS1 1 PROTEIN INSB-RELATED	INSERTION ELEMENT IS1 1 PROTEIN INSB-RELATED					
ECOLI|EnsemblGenome=b4318|UniProtKB=P08189	P08189	fimF	PTHR33420:SF25	FIMBRIAL SUBUNIT ELFA-RELATED	PROTEIN FIMF		cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;cell adhesion#GO:0007155;single-species biofilm formation#GO:0044010	cell projection#GO:0042995;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b3609|UniProtKB=P0AG86	P0AG86	secB	PTHR36918:SF1	FAMILY NOT NAMED	PROTEIN-EXPORT PROTEIN SECB					
ECOLI|EnsemblGenome=b4479|UniProtKB=P31460	P31460	dgoR	PTHR43537:SF21	TRANSCRIPTIONAL REGULATOR, GNTR FAMILY	GALACTONATE OPERON TRANSCRIPTIONAL REPRESSOR	sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067	regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252		helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b1830|UniProtKB=P23865	P23865	prc	PTHR32060:SF22	TAIL-SPECIFIC PROTEASE	CARBOXYL-TERMINAL-PROCESSING PEPTIDASE 1, CHLOROPLASTIC	catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233			serine protease#PC00203	
ECOLI|EnsemblGenome=b0736|UniProtKB=P0A8Z3	P0A8Z3	ybgC	PTHR31793:SF37	4-HYDROXYBENZOYL-COA THIOESTERASE FAMILY MEMBER	ACYL-COA THIOESTER HYDROLASE YBGC	hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;fatty acyl-CoA hydrolase activity#GO:0047617;deacylase activity#GO:0160215;acyl-CoA hydrolase activity#GO:0016289;catalytic activity#GO:0003824			esterase#PC00097;hydrolase#PC00121;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b3084|UniProtKB=P42596	P42596	rlmG	PTHR47816:SF5	RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE C	RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE G	S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a rRNA#GO:0140102;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;rRNA (guanine) methyltransferase activity#GO:0016435;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173	macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;rRNA base methylation#GO:0070475;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;methylation#GO:0032259;macromolecule modification#GO:0043412;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304		RNA metabolism protein#PC00031;RNA processing factor#PC00147	
ECOLI|EnsemblGenome=b3571|UniProtKB=P25718	P25718	malS	PTHR10357:SF209	ALPHA-GLUCOSIDASE FAMILY MEMBER	PERIPLASMIC ALPHA-AMYLASE	hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824			amylase#PC00048;metabolite interconversion enzyme#PC00262	
ECOLI|EnsemblGenome=b0620|UniProtKB=P0AEF4	P0AEF4	dpiA	PTHR45526:SF1	TRANSCRIPTIONAL REGULATORY PROTEIN DPIA	TRANSCRIPTIONAL REGULATORY PROTEIN DCUR-RELATED	molecular transducer activity#GO:0060089			DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b1812|UniProtKB=P05041	P05041	pabB	PTHR11236:SF50	AMINOBENZOATE/ANTHRANILATE SYNTHASE	AMINODEOXYCHORISMATE SYNTHASE COMPONENT 1	catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483	oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;indole-containing compound metabolic process#GO:0042430;aromatic amino acid biosynthetic process#GO:0009073;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038;cellular process#GO:0009987;amine metabolic process#GO:0009308;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039			Tryptophan biosynthesis#P02783>Anthranilate synthase#P03206
ECOLI|EnsemblGenome=b3875|UniProtKB=P76773	P76773	ompL	PTHR38105:SF2	OUTER MEMBRANE PROTEIN-RELATED-RELATED	N-ACETYLNEURAMINIC ACID OUTER MEMBRANE CHANNEL PROTEIN NANC-RELATED	passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;channel activity#GO:0015267	establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;carbohydrate transport#GO:0008643	cellular anatomical structure#GO:0110165;cell envelope#GO:0030313;external encapsulating structure#GO:0030312;cell outer membrane#GO:0009279;membrane#GO:0016020;extracellular region#GO:0005576;outer membrane#GO:0019867		
ECOLI|EnsemblGenome=b0817|UniProtKB=P0A9F1	P0A9F1	mntR	PTHR33238:SF11	IRON (METAL) DEPENDENT REPRESSOR, DTXR FAMILY	TRANSCRIPTIONAL REGULATOR MNTR				helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246	
ECOLI|EnsemblGenome=b0596|UniProtKB=P15047	P15047	entA	PTHR24321:SF13	DEHYDROGENASES, SHORT CHAIN	2,3-DIHYDRO-2,3-DIHYDROXYBENZOATE DEHYDROGENASE				metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092	
ECOLI|EnsemblGenome=b4006|UniProtKB=P15639	P15639	purH	PTHR11692:SF0	BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH	BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN ATIC	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741	nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;IMP biosynthetic process#GO:0006188;organophosphate biosynthetic process#GO:0090407;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;IMP metabolic process#GO:0046040;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793	cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622		De novo purine biosynthesis#P02738>AICAR transformylase#P02900;De novo purine biosynthesis#P02738>IMP cyclohydrolase#P02894
ECOLI|EnsemblGenome=b1294|UniProtKB=Q47622	Q47622	sapA	PTHR30290:SF28	PERIPLASMIC BINDING COMPONENT OF ABC TRANSPORTER	ABC TRANSPORTER PERIPLASMIC-BINDING PROTEIN SAPA-RELATED	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;peptide transport#GO:0015833		transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b3023|UniProtKB=Q46866	Q46866	ygiV	PTHR40055:SF3	TRANSCRIPTIONAL REGULATOR YGIV-RELATED	TRANSCRIPTIONAL REGULATOR YGIV-RELATED		negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219		DNA-binding transcription factor#PC00218	
ECOLI|EnsemblGenome=b0418|UniProtKB=P18200	P18200	pgpA	PTHR36305:SF1	PHOSPHATIDYLGLYCEROPHOSPHATASE A	PHOSPHATIDYLGLYCEROPHOSPHATASE A	catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787	organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid biosynthetic process#GO:0008654;phosphatidylglycerol metabolic process#GO:0046471;glycerolipid metabolic process#GO:0046486;phosphatidylglycerol biosynthetic process#GO:0006655;phospholipid metabolic process#GO:0006644;organophosphate biosynthetic process#GO:0090407		phosphatase#PC00181;hydrolase#PC00121	
ECOLI|EnsemblGenome=b0830|UniProtKB=P75797	P75797	gsiB	PTHR30290:SF32	PERIPLASMIC BINDING COMPONENT OF ABC TRANSPORTER	GLUTATHIONE-BINDING PROTEIN GSIB	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857	peptide transport#GO:0015833;nitrogen compound transport#GO:0071705;transport#GO:0006810;localization#GO:0051179;dipeptide transport#GO:0042938;establishment of localization#GO:0051234;oligopeptide transport#GO:0006857	extracellular region#GO:0005576;periplasmic space#GO:0042597;cell envelope#GO:0030313;cellular anatomical structure#GO:0110165;outer membrane-bounded periplasmic space#GO:0030288	transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003	
ECOLI|EnsemblGenome=b0907|UniProtKB=P23721	P23721	serC	PTHR43247:SF1	PHOSPHOSERINE AMINOTRANSFERASE	PHOSPHOSERINE AMINOTRANSFERASE	transferase activity#GO:0016740;catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363;transaminase activity#GO:0008483;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167	cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038	intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165	transaminase#PC00216	Vitamin B6 metabolism#P02787>Phosphoserine transaminase#P03227;Serine glycine biosynthesis#P02776>Phosphoserine aminotransferase#P03157;Pyridoxal-5-phosphate biosynthesis#P02759>Phosphohydroxythreonine aminotransferase#P03058
ECOLI|EnsemblGenome=b4322|UniProtKB=P24215	P24215	uxuA	PTHR30387:SF2	MANNONATE DEHYDRATASE	MANNONATE DEHYDRATASE	hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824	metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282		lyase#PC00144;dehydratase#PC00091	
ECOLI|EnsemblGenome=b2417|UniProtKB=P69783	P69783	crr	PTHR45008:SF1	PTS SYSTEM GLUCOSE-SPECIFIC EIIA COMPONENT	PTS SYSTEM GLUCOSE-SPECIFIC EIIA COMPONENT	catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772	import across plasma membrane#GO:0098739;carbohydrate transmembrane transport#GO:0034219;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;import into cell#GO:0098657;establishment of localization#GO:0051234;phosphoenolpyruvate-dependent sugar phosphotransferase system#GO:0009401;carbohydrate transport#GO:0008643;transport#GO:0006810			
ECOLI|EnsemblGenome=b1860|UniProtKB=P0A812	P0A812	ruvB	PTHR42848:SF1	HOLLIDAY JUNCTION BRANCH MIGRATION COMPLEX SUBUNIT RUVB	HOLLIDAY JUNCTION BRANCH MIGRATION COMPLEX SUBUNIT RUVB	catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657	primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular process#GO:0009987;SOS response#GO:0009432;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170	protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;endonuclease complex#GO:1905348;DNA helicase complex#GO:0033202;catalytic complex#GO:1902494		
ECOLI|EnsemblGenome=b2660|UniProtKB=P37339	P37339	lhgD	PTHR43104:SF5	L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL	L-2-HYDROXYGLUTARATE DEHYDROGENASE	catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491	cellular process#GO:0009987;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281	cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165	dehydrogenase#PC00092	Ornithine degradation#P02758>Aminobutyraldehyde dehydrogenase#P03055
ECOLI|EnsemblGenome=b0241|UniProtKB=P02932	P02932	phoE	PTHR34501:SF5	PROTEIN YDDL-RELATED	OUTER MEMBRANE PORIN PHOE	transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829		membrane#GO:0016020;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165		
ECOLI|EnsemblGenome=b1864|UniProtKB=P0A8A0	P0A8A0	yebC	PTHR12532:SF6	TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1	TRANSCRIPTIONAL REGULATORY PROTEIN YEBC-RELATED		post-transcriptional regulation of gene expression#GO:0010608;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein metabolic process#GO:0051247;positive regulation of translation#GO:0045727;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794	cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829		
ECOLI|EnsemblGenome=b4156|UniProtKB=P39282	P39282	yjeM	PTHR43243:SF4	INNER MEMBRANE TRANSPORTER YGJI-RELATED	CATIONIC AMINO ACID TRANSPORTER 2, VACUOLAR	transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171	transport#GO:0006810;amino acid transport#GO:0006865;localization#GO:0051179;establishment of localization#GO:0051234		secondary carrier transporter#PC00258;amino acid transporter#PC00046	
ECOLI|EnsemblGenome=b0071|UniProtKB=P30126	P30126	leuD	PTHR43345:SF5	3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT 2-RELATED-RELATED	3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT	hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824	cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;branched-chain amino acid biosynthetic process#GO:0009082;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;proteinogenic amino acid biosynthetic process#GO:0170038	catalytic complex#GO:1902494;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165	dehydratase#PC00091	Leucine biosynthesis#P02749>Isopropylmalate isomerase#P03002
ECOLI|EnsemblGenome=b1706|UniProtKB=P77649	P77649	selO	PTHR32057:SF14	PROTEIN ADENYLYLTRANSFERASE SELO, MITOCHONDRIAL	SELENOPROTEIN O	transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779			protein modifying enzyme#PC00260	
